LOCUS       DACCVH010000001       130086 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.001, whole genome shotgun sequence.
ACCESSION   DACCVH010000001 DACCVH010000000
VERSION     DACCVH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 130086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 130086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..130086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.001"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            212..604
                     /locus_tag="IVV98_000001"
     CDS             212..604
                     /locus_tag="IVV98_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7805693.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IVV98_000002"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IVV98_000002"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP7805694.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IVV98_000003"
     CDS             3165..4775
                     /locus_tag="IVV98_000003"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP7805695.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IVV98_000004"
     CDS             5067..5936
                     /locus_tag="IVV98_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP7805696.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IVV98_000005"
     CDS             6101..7372
                     /locus_tag="IVV98_000005"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP7805697.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IVV98_000006"
     CDS             7369..8664
                     /locus_tag="IVV98_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP7805698.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IVV98_000007"
     CDS             8763..9026
                     /locus_tag="IVV98_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP7805699.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IVV98_000008"
     CDS             9471..9920
                     /locus_tag="IVV98_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7805700.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IVV98_000009"
     CDS             9977..11395
                     /locus_tag="IVV98_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7805701.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IVV98_000010"
     CDS             11395..12255
                     /locus_tag="IVV98_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP7805702.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IVV98_000011"
     CDS             12429..13202
                     /locus_tag="IVV98_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7805703.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IVV98_000012"
     CDS             13349..13714
                     /locus_tag="IVV98_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP7805704.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IVV98_000013"
     CDS             complement(13862..15070)
                     /locus_tag="IVV98_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7805705.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IVV98_000014"
     CDS             complement(15089..15367)
                     /locus_tag="IVV98_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805706.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IVV98_000015"
     CDS             15560..16216
                     /locus_tag="IVV98_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7805707.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IVV98_000016"
     CDS             complement(16658..17455)
                     /locus_tag="IVV98_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP7805708.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IVV98_000017"
     CDS             complement(17452..18636)
                     /locus_tag="IVV98_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP7805709.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IVV98_000018"
     CDS             complement(18661..19908)
                     /locus_tag="IVV98_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP7805710.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IVV98_000019"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IVV98_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP7805711.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IVV98_000020"
     CDS             21888..22202
                     /locus_tag="IVV98_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP7805712.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IVV98_000021"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IVV98_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP7805713.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IVV98_000022"
     CDS             22887..23531
                     /locus_tag="IVV98_000022"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP7805714.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IVV98_000023"
     CDS             23546..23875
                     /locus_tag="IVV98_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805715.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IVV98_000024"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IVV98_000024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP7805716.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IVV98_000025"
     CDS             24863..25687
                     /locus_tag="IVV98_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP7805717.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IVV98_000026"
     CDS             25680..26027
                     /locus_tag="IVV98_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP7805718.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IVV98_000027"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IVV98_000027"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP7805719.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IVV98_000028"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IVV98_000028"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP7805720.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVV98_000029"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVV98_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP7805721.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVV98_000030"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVV98_000030"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP7805722.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IVV98_000031"
     CDS             31684..32451
                     /locus_tag="IVV98_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7805723.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IVV98_000032"
     CDS             32441..34483
                     /locus_tag="IVV98_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7805724.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IVV98_000033"
     CDS             34764..34913
                     /locus_tag="IVV98_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP7805725.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IVV98_000034"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IVV98_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP7805726.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IVV98_000035"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IVV98_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP7805727.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IVV98_000036"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IVV98_000036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP7805728.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IVV98_000037"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IVV98_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP7805729.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IVV98_000038"
     CDS             39330..40412
                     /locus_tag="IVV98_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP7805730.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IVV98_000039"
     CDS             40412..41215
                     /locus_tag="IVV98_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP7805731.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IVV98_000040"
     CDS             41285..42025
                     /locus_tag="IVV98_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7805732.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IVV98_000041"
     CDS             42036..43040
                     /locus_tag="IVV98_000041"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP7805733.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="IVV98_000042"
     CDS             complement(43085..44929)
                     /locus_tag="IVV98_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805734.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="IVV98_000043"
     CDS             45140..45658
                     /locus_tag="IVV98_000043"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7805735.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="IVV98_000044"
     CDS             45786..46469
                     /locus_tag="IVV98_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP7805736.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="IVV98_000045"
     tRNA            46778..46851
                     /locus_tag="IVV98_000045"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="IVV98_000046"
     CDS             47010..47369
                     /locus_tag="IVV98_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAP7805737.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="IVV98_000047"
     CDS             47492..49123
                     /locus_tag="IVV98_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP7805738.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="IVV98_000048"
     CDS             complement(49185..49826)
                     /locus_tag="IVV98_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP7805739.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="IVV98_000049"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="IVV98_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP7805740.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="IVV98_000050"
     CDS             50443..50787
                     /locus_tag="IVV98_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP7805741.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="IVV98_000051"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="IVV98_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP7805742.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51500..54334
                     /locus_tag="IVV98_000052"
     CDS             51500..54334
                     /locus_tag="IVV98_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7805743.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="IVV98_000053"
     CDS             54525..55016
                     /locus_tag="IVV98_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP7805744.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /gene="manX"
                     /locus_tag="IVV98_000054"
     CDS             55119..56108
                     /gene="manX"
                     /locus_tag="IVV98_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP7805745.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="IVV98_000055"
     CDS             56141..56944
                     /locus_tag="IVV98_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP7805746.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="IVV98_000056"
     CDS             56965..57879
                     /locus_tag="IVV98_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP7805747.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="IVV98_000057"
     CDS             57962..58336
                     /locus_tag="IVV98_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP7805748.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="IVV98_000058"
     CDS             58475..58720
                     /locus_tag="IVV98_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7805749.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="IVV98_000059"
     CDS             58892..59956
                     /locus_tag="IVV98_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP7805750.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="IVV98_000060"
     CDS             60202..60627
                     /locus_tag="IVV98_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7805751.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="IVV98_000061"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="IVV98_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP7805752.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="IVV98_000062"
     CDS             61166..62020
                     /locus_tag="IVV98_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP7805753.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /locus_tag="IVV98_000063"
     CDS             62021..63358
                     /locus_tag="IVV98_000063"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP7805754.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="IVV98_000064"
     CDS             63363..63587
                     /locus_tag="IVV98_000064"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP7805755.1"
                     /translation="MENPTFEKSLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="IVV98_000065"
     CDS             63589..64479
                     /locus_tag="IVV98_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP7805756.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="IVV98_000066"
     CDS             64488..65306
                     /locus_tag="IVV98_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP7805757.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="IVV98_000067"
     CDS             65413..65862
                     /locus_tag="IVV98_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP7805758.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="IVV98_000068"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="IVV98_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP7805759.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="IVV98_000069"
     CDS             complement(67617..67733)
                     /locus_tag="IVV98_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP7805760.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="IVV98_000070"
     CDS             complement(67806..68762)
                     /locus_tag="IVV98_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP7805761.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="IVV98_000071"
     CDS             68933..69301
                     /locus_tag="IVV98_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP7805762.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="IVV98_000072"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="IVV98_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP7805763.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="IVV98_000073"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="IVV98_000073"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP7805764.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71288
                     /gene="ftsL"
                     /locus_tag="IVV98_000074"
     CDS             70887..71288
                     /gene="ftsL"
                     /locus_tag="IVV98_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP7805765.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71289..73481
                     /locus_tag="IVV98_000075"
     CDS             71289..73481
                     /locus_tag="IVV98_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP7805766.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMKDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73507..74469
                     /locus_tag="IVV98_000076"
     CDS             73507..74469
                     /locus_tag="IVV98_000076"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP7805767.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74483..75844
                     /locus_tag="IVV98_000077"
     CDS             74483..75844
                     /locus_tag="IVV98_000077"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP7805768.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75870..76958
                     /gene="murG"
                     /locus_tag="IVV98_000078"
     CDS             75870..76958
                     /gene="murG"
                     /locus_tag="IVV98_000078"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7805769.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76973..78193
                     /locus_tag="IVV98_000079"
     CDS             76973..78193
                     /locus_tag="IVV98_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP7805770.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78349..79674
                     /gene="ftsA"
                     /locus_tag="IVV98_000080"
     CDS             78349..79674
                     /gene="ftsA"
                     /locus_tag="IVV98_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP7805771.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79697..80938
                     /gene="ftsZ"
                     /locus_tag="IVV98_000081"
     CDS             79697..80938
                     /gene="ftsZ"
                     /locus_tag="IVV98_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP7805772.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80955..81632
                     /locus_tag="IVV98_000082"
     CDS             80955..81632
                     /locus_tag="IVV98_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP7805773.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81646..82245
                     /locus_tag="IVV98_000083"
     CDS             81646..82245
                     /locus_tag="IVV98_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP7805774.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82260..82547
                     /locus_tag="IVV98_000084"
     CDS             82260..82547
                     /locus_tag="IVV98_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP7805775.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82596..83378
                     /locus_tag="IVV98_000085"
     CDS             82596..83378
                     /locus_tag="IVV98_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP7805776.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83399..84106
                     /locus_tag="IVV98_000086"
     CDS             83399..84106
                     /locus_tag="IVV98_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP7805777.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84368..87166
                     /gene="ileS"
                     /locus_tag="IVV98_000087"
     CDS             84368..87166
                     /gene="ileS"
                     /locus_tag="IVV98_000087"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP7805778.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87215..88741)
                     /locus_tag="IVV98_000088"
     CDS             complement(87215..88741)
                     /locus_tag="IVV98_000088"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP7805779.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88756..89403)
                     /locus_tag="IVV98_000089"
     CDS             complement(88756..89403)
                     /locus_tag="IVV98_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP7805780.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89587..89916)
                     /locus_tag="IVV98_000090"
     CDS             complement(89587..89916)
                     /locus_tag="IVV98_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP7805781.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90093..90821
                     /gene="sfsA"
                     /locus_tag="IVV98_000091"
     CDS             90093..90821
                     /gene="sfsA"
                     /locus_tag="IVV98_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP7805782.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90837..91850
                     /locus_tag="IVV98_000092"
     CDS             90837..91850
                     /locus_tag="IVV98_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7805783.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91850..93127
                     /locus_tag="IVV98_000093"
     CDS             91850..93127
                     /locus_tag="IVV98_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7805784.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93190..95892
                     /locus_tag="IVV98_000094"
     CDS             93190..95892
                     /locus_tag="IVV98_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7805785.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96044..96361
                     /locus_tag="IVV98_000095"
     CDS             96044..96361
                     /locus_tag="IVV98_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7805786.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96391..96711
                     /locus_tag="IVV98_000096"
     CDS             96391..96711
                     /locus_tag="IVV98_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7805787.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96819..98279
                     /locus_tag="IVV98_000097"
     CDS             96819..98279
                     /locus_tag="IVV98_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7805788.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98347..98568
                     /locus_tag="IVV98_000098"
     CDS             98347..98568
                     /locus_tag="IVV98_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805789.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98599..98781
                     /locus_tag="IVV98_000099"
     CDS             98599..98781
                     /locus_tag="IVV98_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP7805790.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98781..99194
                     /locus_tag="IVV98_000100"
     CDS             98781..99194
                     /locus_tag="IVV98_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP7805791.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99317..100498
                     /locus_tag="IVV98_000101"
     CDS             99317..100498
                     /locus_tag="IVV98_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7805792.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            100887..100960
                     /locus_tag="IVV98_000102"
     tRNA            100887..100960
                     /locus_tag="IVV98_000102"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100921..100923,aa:Arg,seq:cct)
     gene            complement(101029..102168)
                     /locus_tag="IVV98_000103"
     CDS             complement(101029..102168)
                     /locus_tag="IVV98_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7805793.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(102467..103102)
                     /locus_tag="IVV98_000104"
     CDS             complement(102467..103102)
                     /locus_tag="IVV98_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805794.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103215..103850)
                     /locus_tag="IVV98_000105"
     CDS             complement(103215..103850)
                     /locus_tag="IVV98_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAP7805795.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103884..104345)
                     /locus_tag="IVV98_000106"
     CDS             complement(103884..104345)
                     /locus_tag="IVV98_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAP7805796.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104475..104906)
                     /locus_tag="IVV98_000107"
     CDS             complement(104475..104906)
                     /locus_tag="IVV98_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7805797.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104924..105244)
                     /locus_tag="IVV98_000108"
     CDS             complement(104924..105244)
                     /locus_tag="IVV98_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7805798.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105543..106319
                     /locus_tag="IVV98_000109"
     CDS             105543..106319
                     /locus_tag="IVV98_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP7805799.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106334..106537
                     /locus_tag="IVV98_000110"
     CDS             106334..106537
                     /locus_tag="IVV98_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7805800.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106553..106891
                     /locus_tag="IVV98_000111"
     CDS             106553..106891
                     /locus_tag="IVV98_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAP7805801.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            106878..107057
                     /locus_tag="IVV98_000112"
     CDS             106878..107057
                     /locus_tag="IVV98_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805802.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(107100..107570)
                     /locus_tag="IVV98_000113"
     CDS             complement(107100..107570)
                     /locus_tag="IVV98_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805803.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            107657..108355
                     /locus_tag="IVV98_000114"
     CDS             107657..108355
                     /locus_tag="IVV98_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP7805804.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            108533..108874
                     /locus_tag="IVV98_000115"
     CDS             108533..108874
                     /locus_tag="IVV98_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805805.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            108867..109538
                     /locus_tag="IVV98_000116"
     CDS             108867..109538
                     /locus_tag="IVV98_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP7805806.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109544..110236
                     /locus_tag="IVV98_000117"
     CDS             109544..110236
                     /locus_tag="IVV98_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805807.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            110233..110982
                     /locus_tag="IVV98_000118"
     CDS             110233..110982
                     /locus_tag="IVV98_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7805808.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            110994..111263
                     /locus_tag="IVV98_000119"
     CDS             110994..111263
                     /locus_tag="IVV98_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805809.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            111426..111725
                     /locus_tag="IVV98_000120"
     CDS             111426..111725
                     /locus_tag="IVV98_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805810.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            111725..112027
                     /locus_tag="IVV98_000121"
     CDS             111725..112027
                     /locus_tag="IVV98_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805811.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            112067..112432
                     /locus_tag="IVV98_000122"
     CDS             112067..112432
                     /locus_tag="IVV98_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805812.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            113059..113241
                     /locus_tag="IVV98_000123"
     CDS             113059..113241
                     /locus_tag="IVV98_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805813.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            113254..113448
                     /locus_tag="IVV98_000124"
     CDS             113254..113448
                     /locus_tag="IVV98_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805814.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(113481..113693)
                     /locus_tag="IVV98_000125"
     CDS             complement(113481..113693)
                     /locus_tag="IVV98_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805815.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            113818..114021
                     /locus_tag="IVV98_000126"
     CDS             113818..114021
                     /locus_tag="IVV98_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805816.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            114018..114290
                     /locus_tag="IVV98_000127"
     CDS             114018..114290
                     /locus_tag="IVV98_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAP7805817.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            114291..114476
                     /locus_tag="IVV98_000128"
     CDS             114291..114476
                     /locus_tag="IVV98_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805818.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            114463..114810
                     /locus_tag="IVV98_000129"
     CDS             114463..114810
                     /locus_tag="IVV98_000129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805819.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            114770..115246
                     /locus_tag="IVV98_000130"
     CDS             114770..115246
                     /locus_tag="IVV98_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HAP7805820.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(115392..116120)
                     /locus_tag="IVV98_000131"
     CDS             complement(115392..116120)
                     /locus_tag="IVV98_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAP7805821.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            116168..116446
                     /locus_tag="IVV98_000132"
     CDS             116168..116446
                     /locus_tag="IVV98_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805822.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            116448..116834
                     /locus_tag="IVV98_000133"
     CDS             116448..116834
                     /locus_tag="IVV98_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805823.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            116831..117211
                     /locus_tag="IVV98_000134"
     CDS             116831..117211
                     /locus_tag="IVV98_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP7805824.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            117323..117775
                     /locus_tag="IVV98_000135"
     CDS             117323..117775
                     /locus_tag="IVV98_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAP7805825.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            117772..119499
                     /locus_tag="IVV98_000136"
     CDS             117772..119499
                     /locus_tag="IVV98_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP7805826.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            119563..120750
                     /locus_tag="IVV98_000137"
     CDS             119563..120750
                     /locus_tag="IVV98_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7805827.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            120716..121291
                     /locus_tag="IVV98_000138"
     CDS             120716..121291
                     /locus_tag="IVV98_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAP7805828.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            121304..122668
                     /locus_tag="IVV98_000139"
     CDS             121304..122668
                     /locus_tag="IVV98_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP7805829.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            122670..122948
                     /locus_tag="IVV98_000140"
     CDS             122670..122948
                     /locus_tag="IVV98_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP7805830.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            122929..123255
                     /locus_tag="IVV98_000141"
     CDS             122929..123255
                     /locus_tag="IVV98_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP7805831.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            123245..123583
                     /locus_tag="IVV98_000142"
     CDS             123245..123583
                     /locus_tag="IVV98_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805832.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            123573..123938
                     /locus_tag="IVV98_000143"
     CDS             123573..123938
                     /locus_tag="IVV98_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP7805833.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            123945..124571
                     /locus_tag="IVV98_000144"
     CDS             123945..124571
                     /locus_tag="IVV98_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7805834.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            124571..125035
                     /locus_tag="IVV98_000145"
     CDS             124571..125035
                     /locus_tag="IVV98_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805835.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            125230..127539
                     /locus_tag="IVV98_000146"
     CDS             125230..127539
                     /locus_tag="IVV98_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP7805836.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            127551..128255
                     /locus_tag="IVV98_000147"
     CDS             127551..128255
                     /locus_tag="IVV98_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7805837.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            128252..>130086
                     /locus_tag="IVV98_000148"
     CDS             128252..>130086
                     /locus_tag="IVV98_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805838.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        43161 a        21840 c        27229 g        37856 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggtg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg taataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaaaagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tacattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt gatttttaaa
    69361 aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg gtagaaagtg
    69421 ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag
    71281 tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa aatctaaatc
    71341 cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt ggattgttct
    71401 ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct ggtacctcat
    71461 tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa
    71521 cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat tcaattaaag
    71581 cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa gaaaagaatt
    71641 ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa gatgcactga
    71701 atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt agctatggga
    71761 aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg
    71821 ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc ttttcttctc
    71881 attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt aaactaggtt
    71941 tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt tatcaaaaag
    72001 ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct gtcgacggac
    72061 aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca ctgatggatc
    72121 aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg
    72181 gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg gaaggattga
    72241 ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa ccaggatcaa
    72301 ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac gagaatgaaa
    72361 ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat gactttggtg
    72421 aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc gggatggtca
    72481 tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg ggatttggac
    72541 aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca ttaaatattg
    72601 tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc caaatgatga
    72661 aagctttcac ttctattgcg aataacggta caatgattca acctcgatat atcagcaaag
    72721 tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta gggcaacctt
    72781 tttcaaaaga aacaacagaa aaagtccgtg aatatatgaa agatgttgtc gaaagcgaaa
    72841 actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg gcaaaaaacg
    72901 gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca gcctacctgt
    72961 attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat ctaacaatga
    73021 aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac
    73081 gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa acagaaaaag
    73141 tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat gctcaaaaaa
    73201 gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca
    73261 acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt gataagctga
    73321 tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa atcctcggta
    73381 ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct ccatatgaaa
    73441 aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa taggagagaa
    73501 aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc aatgacaatt
    73561 gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca ggcgattcgt
    73621 gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg cggcttagtg
    73681 tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa acagctaact
    73741 cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg ctttcttgat
    73801 gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca gaaattgatt
    73861 ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg ttatccaggt
    73921 gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat tttcgctctc
    73981 ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga tggattagtt
    74041 gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca tcagcatcag
    74101 tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt cttcgtctac
    74161 aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt gggcggactt
    74221 ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat tggtttgatc
    74281 tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct tacaggaaaa
    74341 cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg gtcggagtgg
    74401 aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac attatggatc
    74461 gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct
    74521 tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg aattgggcgc
    74581 acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac aagagctgct
    74641 ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg atgaagaatt
    74701 ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag caaaagccca
    74761 agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag cggaatgccc
    74821 aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga caggactact
    74881 actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg ggtatccagc
    74941 aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat tgtctagctt
    75001 ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca atatctatga
    75061 agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat ggaaccttca
    75121 aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag aactacaaga
    75181 attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag tgttggaaga
    75241 cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa tggaaatatc
    75301 tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta tttctgtagc
    75361 aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt tccatggcgt
    75421 accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata atgattcaaa
    75481 agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt
    75541 gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc cttcattaaa
    75601 aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg atgctggaaa
    75661 aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag ttcctttagc
    75721 attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg ccagctggga
    75781 tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga accgattaaa
    75841 atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag
    75901 ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa gaaccgaatg
    75961 ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag
    76021 gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc atgcataaca
    76081 tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt
    76141 ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta gtgtacgctg
    76201 cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca ggtgttacca
    76261 ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat gcggcttcct
    76321 tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa gtagcagata
    76381 ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa acagtcttga
    76441 tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg
    76501 aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat tatgaagaga
    76561 tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat atcaaaaata
    76621 tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca acttcgatcg
    76681 cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat gttacgaatg
    76741 atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa atgattgcag
    76801 ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag
    76861 aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat gcttcaaaac
    76921 gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct tagtgagtaa
    76981 gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt tgactccttg
    77041 gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag agccaaaaaa
    77101 agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa cggttcaaga
    77161 ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag agatcaagca
    77221 aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca atttaaaaag
    77281 tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat tgggtatacc
    77341 gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc
    77401 aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt cattaggaga
    77461 aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta aaaaagcaca
    77521 gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg atttggatgt
    77581 aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc cagtgattga
    77641 aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga
    77701 agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc agttatcatc
    77761 agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca ataaaaatct
    77821 gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata atcttgcgaa
    77881 ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg tgatcgacat
    77941 ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag aatcgggcca
    78001 atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga
    78061 ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat catctgattc
    78121 aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc cgtcaagttt
    78181 aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa aaccagtaat
    78241 ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta aaacggacgc
    78301 tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat ggcaaaaaca
    78361 ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt ggctgaatat
    78421 atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg gattaaccga
    78481 ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt acgacaagca
    78541 gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt
    78601 gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga aatcaccgat
    78661 gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa
    78721 atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat caaagatcct
    78781 cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg acctaaaacg
    78841 atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg
    78901 attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg
    78961 atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga taagcaattg
    79021 aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat ctctattgta
    79081 ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga tgcataccca
    79141 gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc agaaccagtg
    79201 aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca gattttcaac
    79261 aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg
    79321 acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat cttcggcgta
    79381 aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt tacaaatgta
    79441 ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc aaaaattgct
    79501 gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac aacaaacaca
    79561 tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc aaaagagtcc
    79621 ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga ttaattcatc
    79681 ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg gcgcagtaat
    79741 caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa
    79801 cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa aaaattcaaa
    79861 agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg ctggttctca
    79921 gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg aagctttaga
    79981 cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta caggtgctgc
    80041 accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg tcgtgacacg
    80101 tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt
    80161 gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag aagttgtaga
    80221 taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac gacaaggtgt
    80281 acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact ttgctgacgt
    80341 gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg ctagtggaga
    80401 agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg aaacatctat
    80461 tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga cattgttcga
    80521 agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct
    80581 aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg
    80641 tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag cacaaatgca
    80701 atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt cttcagaaga
    80761 agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc ctagagttga
    80821 tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac
    80881 aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta aaaaataaag
    80941 gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa attcaggatt
    81001 cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta acaaaatctg
    81061 ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt gcagaaaacc
    81121 gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa ataaagtggc
    81181 atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa attgattact
    81241 ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta gagaaagaat
    81301 tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga atttcaccag
    81361 atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag gttgttgggt
    81421 tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg tttggtacgc
    81481 tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat
    81541 taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca acatttatcc
    81601 gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac
    81661 agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga ataccaagat
    81721 tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac acagaatcaa
    81781 tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc gacttcacgt
    81841 cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga actacatcaa
    81901 tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac acaacctaaa
    81961 gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga agctatggcg
    82021 attgctaaac gaatcattgc tggagaagca accttagtga attttcattt agtagaagaa
    82081 aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact agatggagat
    82141 atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga gattgacagt
    82201 tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga ggaactacga
    82261 tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc tatagcatta
    82321 tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca gggctaggac
    82381 gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg cctttgagga
    82441 ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta gccgtacaag
    82501 gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg aagcaacaaa
    82561 atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta taccagcact
    82621 ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa caggttcaag
    82681 gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat attttagaaa
    82741 cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat gaacaggcag
    82801 aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa gattttgaaa
    82861 cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat gggaaaatcc
    82921 ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc atctcggacg
    82981 gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct gcacaagtaa
    83041 caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa atgattatgc
    83101 cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta gacagtgtga
    83161 tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa gctggtaaag
    83221 taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta ttagatatta
    83281 tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag acgaaaaaag
    83341 aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg gtttactcat
    83401 ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc ggggatataa
    83461 tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg aattgactca
    83521 aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg agtacttcaa
    83581 tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg ctgataaagt
    83641 aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa acaaagcaga
    83701 tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg cagaagaaaa
    83761 agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga cagaaactga
    83821 agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc ttgagtctca
    83881 attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct ccagctacgt
    83941 gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga
    84001 tactgatgta aactcagaca caggagtcat agaagcacct atgacggcat ttgatacaca
    84061 ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca gaaaagcact
    84121 ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg catggtgaaa
    84181 gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg ctgacctcgt
    84241 tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg taccacggca
    84301 tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata aaggagtgta
    84361 tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg
    84421 taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc gaatctacca
    84481 aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg gacctccata
    84541 tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag acattatcat
    84601 tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg atacacatgg
    84661 attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc
    84721 agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc aacgagcaga
    84781 tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat tagatccttc
    84841 ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaggct atatttacaa
    84901 aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg aagctgaaat
    84961 tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca aagacggcaa
    85021 agatattctt gatgaagata cagcttttgt catttggacg acaacaccat ggacattgcc
    85081 agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg aagccgatgg
    85141 ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa tcggttggga
    85201 aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga ctgcaagtca
    85261 tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt tagacgctgg
    85321 tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg ctggtagcaa
    85381 atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag aagaagcacc
    85441 tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc tattaaaaga
    85501 aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg attggcggac
    85561 gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg ataaattccg
    85621 tcagaatatt ttggatgaag tagaaaaagt agagtgggtt atcccatggg gtaaaacacg
    85681 tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg
    85741 agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac cagaaacaat
    85801 cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg aaaaagaagc
    85861 gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg aatttacaaa
    85921 agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag ctgttttacg
    85981 tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag accaatatcg
    86041 tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag caccatacaa
    86101 atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt
    86161 aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata tccttcgctt
    86221 atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata tcttaagtca
    86281 agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag cgaatacaga
    86341 agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg tagacaaata
    86401 tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt acgacaaata
    86461 taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc tatcgtcatt
    86521 ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt atcaacgtcg
    86581 ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat tgactcctat
    86641 cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg agtacgttca
    86701 gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga tggatacctg
    86761 gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag caagaaacag
    86821 caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac aacaagttcg
    86881 tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt caccagacta
    86941 ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat ttgatgatgt
    87001 tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa
    87061 agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa aaatcgttga
    87121 agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg
    87181 tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt ccacgttcac
    87241 gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt agttcgaaag
    87301 ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt gtttggtccc
    87361 aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc caatgagaga
    87421 agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct tctgggctat
    87481 tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt tcaaatcctt
    87541 gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga atatagatcg
    87601 ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat gttttgaata
    87661 cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca gtcaaacgtt
    87721 tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata gtgaatttgc
    87781 ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg cgatagccct
    87841 tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag ttttctaaca
    87901 cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct gtacggattt
    87961 ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat
    88021 gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg cgatcttcta
    88081 caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg ttccattgag
    88141 cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt tcttttccta
    88201 aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt tgctggttca
    88261 attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa cgattgaagc
    88321 cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca aaaaattgag
    88381 gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca tctaatcggt
    88441 cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg gattgatagt
    88501 aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca cggattgttt
    88561 ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt ccgattacag
    88621 caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg tacaatttac
    88681 gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt tcattagaca
    88741 tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct taaagctgac
    88801 ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg cgatgtcaac
    88861 gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca acaattcttt
    88921 ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact ccaatgtttg
    88981 tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat gaggacaatg
    89041 ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag tcacatgttc
    89101 caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt caactaaaaa
    89161 aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc cgcttgcagt
    89221 caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa gtttagaaat
    89281 catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt tattgttgac
    89341 tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc gatttggtgt
    89401 catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg
    89461 ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt acaacaaaaa
    89521 acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat atacattggg
    89581 agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt cataaagagt
    89641 ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga ctaaacgata
    89701 ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc
    89761 agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg taccttgata
    89821 ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa taaaacttga
    89881 gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca aatcactcct
    89941 ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt accgaataaa
    90001 agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac aaattatgat
    90061 aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg gaaatagctt
    90121 tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac ggagaaataa
    90181 ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca ggcgctgaag
    90241 tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa
    90301 aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg gcaattgatg
    90361 gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg gtatacaagc
    90421 gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg gtcggacaaa
    90481 aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt gcttttcctg
    90541 atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc gcacaagatg
    90601 gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg gcaacgatcc
    90661 atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa agcggagttc
    90721 aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag caggccattc
    90781 catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt aaaataatga
    90841 tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa gcagctttaa
    90901 gcacaaaaaa atatgaattg acagcggtat attctagaca tttggaaaaa gcacaggaat
    90961 ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact tttttcaata
    91021 ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt agtcaagcta
    91081 agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa
    91141 aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt tttgaagcag
    91201 caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca ttaaaagacg
    91261 agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac caagtattag
    91321 atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg atggatttag
    91381 gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa gtccattatt
    91441 tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta cgttatgaga
    91501 attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg tcagagattt
    91561 attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc
    91621 atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa aatccaatgg
    91681 cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca gcttggggat
    91741 tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa
    91801 gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa tgaacgaatt
    91861 tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt ttatctcacc
    91921 ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta tagtagcggt
    91981 ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac taaacgtgga
    92041 accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag ctattcaagt
    92101 agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat ctttggtggg
    92161 cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa tcttgattgg
    92221 tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa
    92281 aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc aaatcattga
    92341 tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag cgacagcaga
    92401 tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac
    92461 agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac cgatacgaaa
    92521 gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc tgattttctt
    92581 taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt
    92641 aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag aacaattcaa
    92701 aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt tagatattac
    92761 aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt atttgcatcg
    92821 ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg tacaagataa
    92881 taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg aagagatttt
    92941 tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag ctcctgcagt
    93001 aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat ataacaaaga
    93061 aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag gagcaaggcg
    93121 caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg ttgccagagg
    93181 aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga aaaccaacaa
    93241 ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa tgcaagccga
    93301 tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg accagtcgtt
    93361 tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa
    93421 gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat acagcaggca
    93481 aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg agaaactggt
    93541 acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc agagatgctt
    93601 tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg
    93661 ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc tcaagatagt
    93721 cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat ccaccgttta
    93781 ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta ccgtccgctt
    93841 ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac gactgaatct
    93901 tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac cttgccgaat
    93961 cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat caaacaagaa
    94021 gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc cttcatgctt
    94081 tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa
    94141 tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa agaagaactt
    94201 tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg tctcgaccga
    94261 ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga tgttgtctgg
    94321 tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa agtcacttct
    94381 ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa agatgtggat
    94441 gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa agatcttttg
    94501 ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa acggttagac
    94561 cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag tacattggat
    94621 cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg gaaaaatttt
    94681 aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga agaacaagtt
    94741 gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa tctaggagaa
    94801 agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg cagacagact
    94861 gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg gaaagctttt
    94921 aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca atatgtcaaa
    94981 aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg atcattaaac
    95041 accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat cacgatgaca
    95101 agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag cttagaagat
    95161 atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa
    95221 aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac tggtgaagga
    95281 gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa ggtagaactg
    95341 atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc cttattggaa
    95401 gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa tatcccattt
    95461 ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg tatagctgat
    95521 gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag cgatgtcttt
    95581 tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca gaccgatttg
    95641 tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc cttcatgtta
    95701 gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat tttctcaaaa
    95761 atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga acgaaaatat
    95821 caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct tgaaaataaa
    95881 ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg tgcgcactat
    95941 aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt ggcatgcttc
    96001 ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat
    96061 catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc
    96121 agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag atgcagataa
    96181 taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac gtttcatgaa
    96241 agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca tcaatatgca
    96301 agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata
    96361 aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaatct agaagccatc
    96421 atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc gattgcggct
    96481 gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga agaatcactt
    96541 atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg aaatcatatg
    96601 caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat tgcgtttact
    96661 gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata aatacaactt
    96721 cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt ataaggagaa
    96781 ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta tcaagttgga
    96841 tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt
    96901 tgcgtgatgc ttttatcggc atactgcccg caacaatggc gggatcagtc gctgtaatga
    96961 tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct gacagtttag
    97021 cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat ggttttgtct
    97081 ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg tataatcttg
    97141 cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct accttgattc
    97201 aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt ccttcaaatg
    97261 tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc acactgtcag
    97321 ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat tttacagtta
    97381 tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc aacattacga
    97441 tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc attttaccag
    97501 cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt gtagctgatg
    97561 ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta ggattatctc
    97621 aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg ttctttggta
    97681 ttcatggatc aaatgtattg gcaccagtgc tagagggaat ctggggacaa gcacaactaa
    97741 tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca gccgtgttag
    97801 atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat gcttttgcat
    97861 ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt ttctctaaac
    97921 gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc aatatcaacg
    97981 aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc ccattcttga
    98041 ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc ctagtcgctc
    98101 cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc ttagcaacag
    98161 gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact ttcttgattt
    98221 gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag
    98281 atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga
    98341 actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa
    98401 ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc
    98461 tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa
    98521 gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa
    98581 aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg
    98641 atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca
    98701 ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa
    98761 gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt
    98821 tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag
    98881 taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg
    98941 ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa
    99001 cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg
    99061 ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt
    99121 taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg
    99181 aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc
    99241 tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt
    99301 aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga
    99361 aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg
    99421 ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct
    99481 aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat
    99541 ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca
    99601 gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc
    99661 gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag
    99721 ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg
    99781 tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa
    99841 ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg
    99901 caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta
    99961 tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt
   100021 ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc
   100081 atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat
   100141 gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc
   100201 atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg
   100261 gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga
   100321 acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg
   100381 gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga
   100441 agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact atttttgata
   100501 aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa
   100561 ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt
   100621 ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt
   100681 ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag
   100741 gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa
   100801 cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa
   100861 caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct
   100921 cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tataaataac ccctgtatcc
   100981 tttgcggtac aggggtttgt tttgtatttg tgccaaaaat gtgccaaact agttatcatt
   101041 tttatataaa ctatcgaaca cagtattgat tttttcttta tcctgatctt caagctctcg
   101101 aacaatatga agataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga
   101161 tacgctaagt atatttactc cttgataaag taaaatagat gcatgtgtat gccttagtcc
   101221 atgcaaagta aattgctttt caatccctaa ttcttttaat tttttgcgca aatatttgct
   101281 gacggcgttt gatgaaacta atccattttt taagttgaaa aaaacaaaat tatgagggtt
   101341 tttgatttca aaattctcga ataattcttt ttgattgatt ttaaactttt ttaagagatc
   101401 aatcgtatgt ttatcaatgg aaattttcct atttgaagtt tcgttttttg tttttcccca
   101461 ttcatttaat ttataattcc atgttttatt aatagtgatg atttgatctt cgaaatcgat
   101521 atcttcccat gttaatccta gaagttcagc aaatcgcatt ccagtggcac cagcaactaa
   101581 cacgagcata ggagaagagt actgcgcaga aaggttttct tctacgagtt tcattaaaga
   101641 tttaaattga tcataatcta aatatttatc ttcttttggc ttcaatgaat cttttccttt
   101701 gattactgct tttctagttg gatcaaacgg aattaatcct tcttctacgg catctttcaa
   101761 cgacgctcta atatggttat taaacttaat aacggtagat tttacatggt ctttagcata
   101821 cttatttaaa aagcgttgat atcccactct atctaaatca gaaatcaata ccgctggcat
   101881 atatttcttt atgttcatta acgtatcttc gtattttcta taagtgatag gagatactgt
   101941 tccttcttta taaagttgca tccaatcctc aaagtaatct gataataata gatttttgcg
   102001 atccccttta aggcctttgt tcaagttata ttctaattcg ttggcggcat cttttgcttc
   102061 tccttttgtc ttaaatcctg attttcttat cttcgtgtat tttccgtcat cttttttgta
   102121 tgaaatttcg tattgccaac tatttccacg tttgactaat cttgccataa ttgaatcagc
   102181 tctctttctc tgatacaata ggaactataa agaagcccat tgtttgggtt ttattatttt
   102241 ttgcacatcc tttttgcttg ccggcgcaag gatgtgctat ttgtcgtttt aatggtataa
   102301 ttggatgtgt attagatcat ccaatcagag gtgtttatta tgattaaagt gatttttaaa
   102361 agaataactg aacttccaga gtttagatta tttgttgatt attggtatgt ctggtttttt
   102421 attgttgcat tgctgatagg tctagatgtc atattagaaa gaaaacttaa gtaagagttg
   102481 agttaataaa ttgaattcct aaatgagata ttttgtagcc catattttgt ttgccgacat
   102541 cacctaatac tatggagcta atcgtttttt ctaacagacc aaaatcagat aatctattta
   102601 agctaccatc tattagctct tgtgaatagc cagacatgct gatatttcca gtgaaatttt
   102661 cgtttccacg actcattaag catgctaaca attgaatctc aatcgatgtt aattgattca
   102721 gtacaagaag ataatactcc tcgttatccc atgaagcgtt gttaattcga agtaaacaat
   102781 tcttataaag atttttatac atatctattt tattttgtgc ctttgatttt tctacctcgt
   102841 catttatccc ttcgaatatt ccaatgagtt ggtccttgtt ctctaagttg aaaacatctt
   102901 ctggaatttg atcgcgaatg ttttctaatg attcgtttaa atttttgtag aatttctcga
   102961 tgcgtttgaa acgcttctcg tttttagacc caaaataaag tgactgcaca acgccaccaa
   103021 tataaggaat tgctccaata ccgccttcaa ctattaattc aagatattct tttttggtta
   103081 gtttttcatt gctattatcc atagttacct cctattttgt catttccttt acaagcattg
   103141 tgactcctga tggcactctt ttgtataggt tttattattg tgcacaatct aactcttagt
   103201 ggggcgtggt tcatttattt tttacttact ttactattaa tcatatccca ttgagcatag
   103261 gatttttcta tgttcgatcc tcttgaacta atttctcctg taaaagttac tttatcgccc
   103321 tttgtaaagg tatcagcatt gtttaagtcc ttcgcaaaaa ttacatatga aactttaggt
   103381 gttgcagaaa tatcattcca acttttatca tcgtactctt tgtctgctat aatggctatt
   103441 ctagtagtca ttgattcgat aacagttcct tcaaaagtat atgttttacc actaatatat
   103501 ttagtaaaag ctgtattttg ctcagtagct ggagtaatag aataataact atctaagaaa
   103561 gcaccccagt catgattatt tgtctctaaa aattcttcaa attgagttag gcttttattg
   103621 ctgctgttag atgtagtagt ttgagtatca gatgatgagc tttcctgttt gttattgtca
   103681 tttgcctcgt ttgatgagga aagcgagaaa cctacggtag taaaaataat cccgataata
   103741 aggagaatca taggtgtttt cttatttgtt tttttgataa atcttacaat taacatgatt
   103801 aaacctataa taaataaaac aataccagta aaaccaaata taccgtccat taatagatcc
   103861 tctttctctt ttgatattga atattataaa ccaagcaatt cttttttctt aaaatcgaat
   103921 tcttcttgat taataatccc ttcatctaac aactctttat actttttaat ttcatctgca
   103981 cttgaaattt gtgtttcttt ggaattatta tctaatatag attgttgctt ctctatatat
   104041 ttttttaaat tttccatttc attccaatat ttttttgtaa acataacggt gttttcatct
   104101 ttcgtggccg ctaatatacc tccgcgactt tcgtttccgc ctagcaaggt aaattgtata
   104161 taaccattac tcatacctgg tttttttaat tgtacggctg atatattttt aaaggggata
   104221 gttttttctc ctttaatacc ttgattaact aaatttataa atccttttct aataattgaa
   104281 atagaatcat cagttacttt aatcaaggtt tttcctggag attttattaa aatctctttt
   104341 tccatttttt cttcctcatt tctgtgatat gatttttttt gtagaagctc atatatgagg
   104401 aaagagcccg tgttgcagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat
   104461 aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat
   104521 tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata ctccataaat
   104581 ttttcgagat taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa
   104641 attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta
   104701 tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa
   104761 tgaaaggctt ctgcagtttc accgtataga ttttcattca aaaaaatgat tctgggtttt
   104821 ggatagtaga aaccaggctc tttcatctcc atataaacta ctttcaaatt gtattcgctc
   104881 aacatttctt tcaatttcaa atacatacaa accatcactc caactattca ttttcctcta
   104941 aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct tttccatcaa
   105001 aagaaaaaac agtatcgtct tctgataaat ccacatgttt aggggtttct ctttcttctc
   105061 tacctagaag gtagtctaca gagacatcga aatagtcagc aatccgactt aattcatctg
   105121 aattaggagt attatttttc cactttgcta gataaccgtt agaatatcca aaattaattt
   105181 ctaactgccg tatagatatc tttttcctct tcgccaagtc ttttattatt tcataggtat
   105241 tcatcgataa aacaaccttt ctaaatgttt acaaaaaaag tttagaaaaa tacgcagaaa
   105301 taatttgact aattctgagt aatgagctat actatatctt gtaaacagat ttaacaacta
   105361 aaaagacaac aaaaaacact attgatatgt aaatgcagac cgccaagaaa gctttaaaat
   105421 caatgttttt atgtcttatt taattatgct cttagtatag agtattactc agatactgtc
   105481 aattgaattt agaaaaaagt tgttaaattt gtttacgaat ataaaagaaa ggaatgagaa
   105541 atatgaacac accgcaaatt tttaatttcg aacaaaacga agttcggaca attttagtaa
   105601 atgatgaacc atattttgta ggcaaagacg ttgcgagtgt tttgggttat tcaaacacta
   105661 aagatgcttt gtcgcggcat gtagatttgg aagataagat ggggtcgcga atcacgacct
   105721 caggtcaatc aagagagatg acaatcatca acgaatctgg tttgtacagt ttaatcttaa
   105781 aatcaaaact tccctctgcc aaaaaattta aacgttgggt aacaagtgaa gtgttgccag
   105841 caattagaaa acatggaggt tatctaactc cagaaaaagt agaagaagct ttgcttaatc
   105901 cagatacaat cattcaatta gcaactcaac taaaagaaga aagaactgga agattaatcg
   105961 cagaacaaaa gattgcagag tacgaaccta aaatctccta tttagatagc atattatctt
   106021 ctacagattc agtaacaatt agtcagattg cagcagatta tgggatgtct ccacaacaga
   106081 tgaataaatt acttcataaa ctaggtattc agaaaaaagt cggtaaccaa tggttattgt
   106141 gcaaaaaaca catgaaccaa ggatacacaa aatctcatac aactgagatc ccgaaagccg
   106201 atggtggcac taaaattgta atgaatacca aatggacaca gaaagggcgt ctatttatct
   106261 acgaattact aaaaaaagaa ggatattacc ctcaaatgga tttagaggaa attggttaga
   106321 aaggagtttt agtatgactg acattgcaga aatcactcaa cgagatagag aaaaaatcaa
   106381 agaatatgtc gaaagttcaa agttcttaac ttacaccatg cttgctgaaa gatttggaat
   106441 tagcaaaagc tacttatctt taattttaaa cggtaaaaag acttctgcag aagcaaacag
   106501 aattatagat tcgattatca ctatgtacga attgtaaagg gaggaacagc taatgcaata
   106561 tctagaagca aaaatcccaa ttccagaagg ctatgtaatt atctcccaag tggattatga
   106621 ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag tgctagaacg
   106681 gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa gatatagaaa
   106741 tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg aaggaagaga
   106801 cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt tttcggaaat
   106861 cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc gcaccgctaa
   106921 tcatctacgc tttaggactt tggggaagca ggcaagcgtt gataggaacg attgtttaca
   106981 tggtttggat ttttatgggg cttgatgaag ctgaagctga gtacagagcg aaaaagccaa
   107041 ccgagggggc tgactaaaaa tgaatagaaa agagaaacta gaatgtatat tactattact
   107101 cagtttaatt ctttcactaa tttctctatt gggaagtttg tatttttgat atcaacaatt
   107161 ttgtggattt gggttctatt tagagtaaat atcatttttg tttggtgatt aaggagttta
   107221 ttaaaattaa ttttccctac ttcaaatgca aggtaacaag atatagcact tttaggagga
   107281 atatttagcg gtacagcttc agagtatatt ctattatcat cgactgatcc tcctttagca
   107341 attaatttct taaatggagt agctgaccat ctgcggttta agttagcgga tgaaagttct
   107401 aaattaacta acatagctgg ttctgttgaa tagttagaaa tgattacttt tgtataaatc
   107461 atatctgcag cgaagtaaga agcattaagt tcaacttcta gttgagggcg cattcctttt
   107521 atttttatcc ctgttaaaaa cgtactcaat ataaaactta ttattgacat ccattgaaaa
   107581 attgttaagt gaaaaaaatt caaaataaac accaccagtt tttaactaaa ttataccaaa
   107641 aaggagagaa gaaataatgc aagaattagt aattttgaaa aataaagaag ctgtgactac
   107701 gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa gagatattga
   107761 tgcactaaaa aaagatgtgt ccaattttgg acagatgttt gtagaaggta atgaaccaga
   107821 ttcatatggc agaaatcgac gagttttctt cattagtaga gatggatttt tcttgctggc
   107881 tatggggttt acaggaaaga aagctatcta cttcaaacaa aaatacattg aagcattcaa
   107941 cgaaatggaa gatgttattc gcaagaatac tgttcctcaa acaattgaag atatgatgat
   108001 ctatcaatta gaagaaatga aagatgttaa aaaagatgtt tccatgctta aagatactat
   108061 gcgaattagc ggacaacaag agtttgaaat taagcaaaaa ggaaatatga aagttatggg
   108121 agttctaggg ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag tattctcaaa
   108181 attttggtct gaatttaaac gtaccttttc aatcccaaga tatggcgagt tacctcgtaa
   108241 gagattcgat gatgctgttt catttattga aatgtggttg ccagaaactg cgatccgtat
   108301 ggaaattgat caactgaaca gacaacagag actttttggt gatgacaatg aatagagctg
   108361 aagcgctaag aatagggacg gcaattgcta attgctggtg gaaatactat aaaccaatca
   108421 tcctaagcca acaacatatt gacaagcaaa aagcatggca acaaataaaa aagtgactcc
   108481 gccggcaagc aaagagtcac aaagaaaaca catcataagg agattttagc atatggaaaa
   108541 agaactttcc actctagatc aatatttgat tgatcctgat tggggcaagc cgaaaattga
   108601 ggaaacaagt ggtcgaaaaa tcagacgaaa tcttttgacg aatgaagaac tagcttggga
   108661 tcaagatgat ttaggcaacc atgtaactat ttgggatcat gtttatctta tccatctatc
   108721 gaagcattcg aataaacctg aatatattta cgtcatcgaa gatggcttga ttgatgcgct
   108781 agaagagtac gacagagata acttgattga tatctcttat tacggaccag gtaagaaata
   108841 cattgctgaa atggaggcag aatttgatga gtgaaatcaa agggacaacg aactttgaaa
   108901 aactttttag tcgtaagtta aataaaattc tcaagaaaaa aggaaatttt gattatttat
   108961 cttgggctca cgcgtgggag attatgaaaa agaatgatcc acaggcaacg gtaactatta
   109021 atgagtacaa acactacagg gttgtttctg gaactcatca agactttctt gttgaggaat
   109081 ataaaccttt tcttatggat gaaactggga cttatgtatc tgtctcagta acggttaaag
   109141 gacacacgga aaccgaatta tttcctgttt tagattatcg aaaccaacca gttgttaaac
   109201 caaatgcaat gcaaatcaat aactcattga agcgatgctt tgtgaaagca ttggctctac
   109261 acggactggg attatatgta tttcaagggg aagatattcc aacaccacct agaatcgata
   109321 caaagaaatt aaacatgcta gagacgattc tagaagcttt caatgagcag atgggtaaag
   109381 atatgaccaa aaccttaatc gaatatgtta atgagcagac agataaatta gggctcttag
   109441 ctgataacgt tgaaactatt gaacagttaa gctatgagca atgtgccttg atggagcgag
   109501 caatagcagc taagagaaaa gaattagata agaagtgata tgagtgttta aaccattaat
   109561 cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa gacataagcg caaccatcaa
   109621 tgaggaagtg aacattgatc gactaaagac gatgtatgac ggctacgatg gtgatcgagt
   109681 cattgaaatt cgttttattg atcctagacg tttcaccgta cagcaacgaa acttcatcta
   109741 tgcgctgata ggcgatattt ttatcgatac aggcatgcca acggacttct ggaaggaatt
   109801 cttctacttt cgttttgaag gtgtcacagg gcgcaaaata agcctgaaag acgaatcgaa
   109861 tacaactgtg agtgatgcca atgtcttagc aaatatcatc ttagatttca tctttgaaca
   109921 tcatattcct ttcaaagaag gctatgagat tttacctgcg aatcaagaat attacttcta
   109981 caaatgcatc acaaaaagag tctgctgcat ctgtggcaaa acaggagctg acatcgatca
   110041 ctttgacaaa gcgctaggaa gacgaaagcg caaagaagtt gatcatgcag agtacacatt
   110101 tgcagcactc tgcagaatcc atcacacaga gaagcacaaa ataggtgtga ttaatttcaa
   110161 aaataaatat caaatcaaag ggatcaaatt aaaccagaaa acaatcaaaa agttaaatat
   110221 tggaggggaa aaatgacaga acatcgaagt tattatgcga ttataccagc caacgtaagg
   110281 tacgacaaaa gacttaaacc aaatactaag ttgttatacg gagagataac ggccttgtgt
   110341 aatgaaagag gcttttgttg ggcaggcaat gagtactttg cagatttata tggtgtgaat
   110401 aaagagacca tatcgcgatg ggtaagtgat ttgattaagt ttggatactt gaatcgggaa
   110461 atcatttaca aagagggtac caatcaaata atcaataggt acctacgaat taatcaatac
   110521 cctattgacg aaaaacgcaa tacccctatt gacgaaaaag tcaaagataa taatacatct
   110581 attaataata catttaataa tacaaaagaa tatataagag agttaccgcc ttcgaaaaaa
   110641 tcgaaggcta agcccgtccg tcataaatac ggagagtata aaaatgttct tttgtcagat
   110701 gagcagatgg agaaactcaa aacagaattc cctaatgatt accaagagcg aatcgaacga
   110761 ctgtcagagt attgtgaatc atctggtaag acttataaaa actatttggc aactattcga
   110821 agttgggcaa ggaaagaaaa aagtgaacct aagaacgcaa gcagtggata caagcgcaca
   110881 ggaagacgag agaagcttcc tgaatgggca atcgaccaag aagcctatct caagaaaaaa
   110941 gcgctagaac gagctaatag acaatcaaaa gcaccattct aagaggtgga aaaatgaaga
   111001 tcgattatct agaactaatt aatgaaatag cgaattataa aaagggcgag gaattagacg
   111061 tcctgagaga cgtatatgat caactcgaag aagctggaat tgaaggaatt aagaatgatc
   111121 gttcgagttg gagtaaactc agatactatt tcgcactcta tatcgatgga acgcaattaa
   111181 gaaatttagc atataccaaa ttactattca ttgattgtgt taaaggcttg caaaaacatc
   111241 ttaatgaact tgagcaggtg taaacaagat ggacctaaag acatttacag cacagatcga
   111301 attaatgcat caagaagctt taagacaaag tgtgtcgtac gaagacaagt ggctcaacac
   111361 atttcatggc ggacgtgaga gcgcacttga tcaagtactc aaattactga aaggagaatg
   111421 tcgggatgga taagaaagcg gcaatgcagc gaattatcga attgacttat tcagaagatt
   111481 ggcaggaaga taaaaaaata gttgcagaag tccaaaagct cggtaaatca atgtggactg
   111541 aaaagcccaa acggagaacg ccgagaaaga ttgcaatctg gcatggtgat cgaattctag
   111601 taacgggtac cgctaaacag ttatctgaaa ttactggtct gagcaaaaat attatttggg
   111661 atagagctag gagcttatgg attgattcaa aaggaagaca gtttaggtat gtggaggaga
   111721 aataatggac gaactaatcg cgaaagtaga gcagtgggca aaagataagg gattggatca
   111781 agcggatttc agcaagcaaa tgttaaaaac ggtcgaagaa atcggggaag ttgccgcttc
   111841 tctagctaga aaagatgaac atggtttaag agacggaatt ggcgatgtag tagtaacctt
   111901 gatcatcttg gcaatgcaaa atgatatgga tttatacgag tgcttggatt ttgcttatga
   111961 cgaaatcaaa ggtcggactg gaaagatggt caatggtgtt ttcgttaagt ccagtgacct
   112021 gaaataattc cattaatgga agaaataact gaataggagg atagacatga ttgatgcaaa
   112081 acaagtgcaa aaacagaaag atggaatgtt gatgtttgaa gcatatgttc taccatttct
   112141 taatcaattt gaagttttgg aatgctctgc cagcggagaa gaattggagt atgttgtaat
   112201 tcgtgaaacc aaagaaaacg ttcagaagct aaacgaattt ctttgcacta ttaactgttg
   112261 ggatatgata gctccaggat ttttatgtcc agctatggga gaatttttgg aatattgtcg
   112321 tcttgaagat gcaggcactt tggatttagc ttatctggta tacaactacc taaacatcaa
   112381 cacagatcat ttgtggtttg gcactgccga aagaaaatgg gtagtccgct aaccaccaat
   112441 atcaatgaaa aaaggcggtt tcctgaaagt ggaattgccg ccattgctgt aaggttcttt
   112501 acgcgactca aggtcacaga aatataaatg caaatctctt ttgaagtgat ccaaagctct
   112561 cggaaaatgg aagttttttg tttcaaagaa taaatgagat ttgcgtcaag aacctgagag
   112621 ttatttccaa aaaagcttcc aaagaaccga atgagctaag gacatcatgt gtaaacacat
   112681 aatatagctc tcctttcacg gctaatcata acatgaaaaa tattcgatgt cagtaggaaa
   112741 aaaggtgaat tatgaaaaga atattaaatt atcccggcag taacagattc tgcaattaaa
   112801 ctccgaagct gatgtatcag tatcaactgt agaatattat gagcgtggag aaagtcaagc
   112861 agtcacaaat gtaaaaatcg ataacgtcaa cggtcttatc tgtttagatg aaggcgatag
   112921 tatgaatgaa attgctgcag accatgaatt atcagaaact gctttaattg atcaaatcga
   112981 attagctaga caatactttg ttccatatgc agatacctgg tccaagcata agaatgacat
   113041 catttttcca gaggaacaat gagagcaact gatccagtaa ttatccttga ggaagccaaa
   113101 tttatttgga ctcacgaaga gatagagcaa gcacgcttgc tcttttctca aggagttaag
   113161 ccgagcaaag tagctgaaat aatgggtcaa aagattcttg atgtcggatt gcttttgctc
   113221 catctagcag aaaaaatttg atttgaggtg aaaatgatga ttcaacttgc aggcatccaa
   113281 acagggaaaa tttatttttc tggagaaagc aaaagcgaag ccaaccaatg gctattgaaa
   113341 acttacacga acaataagaa gctaaggaaa aaatatcctg atttgttgct aaaggatgat
   113401 cagattatgc cggaaccgat gattttgacc cgtaaggagg gaagttgaaa ctaaaaaacc
   113461 agccgtgtgg gctggagttg ctatttcttt ttaataatga gtttttctaa atttaattca
   113521 ttctcacgag tttgcgtcca ataatcagaa taatatttta attgtttaag agtaggaatg
   113581 tcgtcttcgg taaaattaga aaataattct ggagaattat ctttttttaa ttgttctaat
   113641 cctgattctt taaaacgttg ttcaacgagt tttactaaat tgttgatatt catgataaat
   113701 caccttttta aatttaattt cgatttgatt aatcgataca agtattatat caaataaaaa
   113761 agctgattta gggggtctta caaaaacact aaaatttttt caaaaagagg aggaacggtg
   113821 gtgaaagtca gagaacaatt caagatagtg agcgacgaag gtaatgttta caaaataaag
   113881 atcgttaata ttaatgaata tcgagaagca gatcacaaat atttggttga cttatacatg
   113941 aacgataaat atttgggaga aggattttgt ggagattcac tttttgatga tgagcgaatt
   114001 ttgaaggagg aaacagaatg atccacgaac taaaaatact accagaatat tttgaagcag
   114061 tgacgagcgg acgcaaacaa ttcgagatcc gcaagaatga tcgtgacttc aaagttggtg
   114121 atcagttaat actacgtgaa tataaaaaat acattaaaca tgaattacct ggactaacga
   114181 gaccaacatt tagttacact ggtgactcat acaaagcaga gatcacttat attactgatt
   114241 acatgcagaa gtccggatat gtagtgttgg ggattaaagg ggtgaattaa atgaaagtat
   114301 acatcttagc tatcacagag ggcacatgga tgttcccagt cggttccgga aaaatctata
   114361 aatcaaaaac agctgcttat aaagcatttg aaaaatacaa aaaagaaaac ggtggcggca
   114421 ctaacgcaaa gattctagtg gctgataact ggcatgaaga aggtgaacgt aattgattta
   114481 cctgttcatt ttcgtggtac taactatttt tatgctagta atcttattca aaaaaagatg
   114541 agtaaagacg aacgaaaaat tctggccaac ttttatttag tattaaaaat cgaacaaaat
   114601 gtgttttcgg aaaggagaat tgtatgggaa aaacaaaatc aaagattaag aagaaaaaac
   114661 gacgtttgga acaaaaggca atccagaatg gaacggctaa gaaaaaataa aaaagctacc
   114721 cctttcgaga tagcagcgca atactattct accataaggg gtggcgtttg tgagatttca
   114781 ttggttaaaa gattaccaag aactagatga gcagattctt tacttaaagt ggaatcttaa
   114841 taaaagtaag cttgaattga atcgatgggt ctgtggtgat ttagcaaacg tccgcatcga
   114901 aaagaattcg agaacttctt ctttagaaga gaatatccaa aagatagaaa atgaattgga
   114961 attgttgatc gagcaaaaag aagaaatgtt attgctgata gatagctttt ctggtatcga
   115021 taatcaaatt gttaagatga aatatgttga tcaaatgagc ttagaagata ttgctgaatc
   115081 tgttgggtat agctcatcgt atgtcagaca gcgacatgca gaaattagaa agacattgaa
   115141 ctttttagat gagtatgaac acagacaagc tgaccgattg aaaaaagaaa acgaaattga
   115201 tttttacaat agcgagaagt acaaagaaca actctcttta ttctaaaatt acactgttca
   115261 ctaaatgttc ggtcattgta gctatgtaaa cattgttagc agcatgatat tctattagtg
   115321 tcaaaaaaat atgaaagagc caagatatcc caaccgtttt attaattggt atctgtggct
   115381 cttttattct tttaattagt agttggcata aagttatttc catttataaa ttgatcagct
   115441 aaatcagcat cataatcagc cgcgataaat tgcgctgctg atttaataaa tgcatccata
   115501 tcatgaacat ctttattagt atgtctacga acatagtgcg tttcatcatt accaatccaa
   115561 gtagcagctt tggctaatct ttggagttta ggaaaatcat tcaaataatt ttcaattgtt
   115621 ttacctaata acattttttt tattttatct tcatcctctg aatttttaga tattgcataa
   115681 tctttaatta gaaattctag agcttttcta taaccaactc cagcaatttg ttccaattgc
   115741 tcagatttag cttgtgtggc ttgagtataa atatcaacaa atgtaggaga aactttttca
   115801 atattttctg gtaaatctat tttaatcggc ggacggtaat aatctttaat taaaatattt
   115861 tcagaatatc cttcatcttc attaaacgta tttataaatt gtaaactata aaatttgttg
   115921 cactcatcat ttatacactg tactaatacg ccaaagattc tatcattatc gaacgcacta
   115981 tatgatgaaa ccccaaaata cacatacgga gtcattatat ttccgcaatg cggacaacta
   116041 tttggcaaat aaattgtctc tgtattttga cgatcacgat acttaatatt aacttcttga
   116101 agcattaaaa cacctcgcat cttttttata aatcatacca caaaatatct gataggagag
   116161 taaacaaatg aatgattttc atgaagcggt acttagtatt gaagtagaat caagtttggc
   116221 taaagtttat aagaaagcaa ttgaagcaga gaatagtccg tacagagaaa attggaatgg
   116281 taatcatgca catgtgcaag tggagaatga tgattacaga actggaatga atacgttagt
   116341 tatttcttta ttgtcacaca ctctacccaa tctgcaggaa acgattgaat ggtatgagcg
   116401 aatgggcgca aaagtaatcc gtacaaatta caaaggagag aattaaaatg gcaatgatca
   116461 aaattagaac atccattagt ggaacagagt attgggattc agaaaagaaa aggacagtag
   116521 ttgttccgaa agatcaagaa ccaaattttg aagtaaaaga agaaaaagga attttgagtg
   116581 atggcaaatc atttgttgct gtcaatggcg aactcatagc tcatagcagt gaaattcttg
   116641 atagcgatgg aaacactgct gctaattttg atggagacga agctactaat gatcagtcca
   116701 ctgaagatac ggatgaactg gacaatatga ctgcaaaaga attgcgtgca tatgctaaga
   116761 aacatggtat tgatattcct ggtgctatcc gtgcaaaagg cgatatcata aatcttattc
   116821 gtgaagtaga atgaaatact gtcagtttga cggatgcacg aacaaaatag caaagggtat
   116881 ctactgtact gaacacaaga gatcaagcag atcacgcaag aagaagcagc aagcaaagtc
   116941 tgtttatcat catgagaaca aaccattcta tcgaacgcaa gcatggaaag atatgcgtca
   117001 atttatttat gaaagagaag gtggtcattg tcagcggtgt ggtcagttca tatttggaaa
   117061 gagagcacac gtccatcaca ttgtaccaat caaagacaac gaactgctta agcttgatcc
   117121 aaacaatctc atgctattat gttcaaaatg tcatccaatt gttgaaaacg aaacggaaga
   117181 caaaaaagtt tttccttcgt atttcaattg aagcccccct attcattttc aaaatttttt
   117241 cgcgtgggga gatagggtag cggggagtca cgcgcatcgt taggtcaaat ttttcaaaaa
   117301 acaaaggggg gtgtatacaa aaatgacgac taaagcgcaa cgtaaagcga ttattgatga
   117361 aaaagtaagt gctgaaaaag ctcgtatctt agaaataatg aatttgtctg atttgtacac
   117421 catcactctt gatccattaa tcgaatcata cttggatatt tttgaaattt accaacacaa
   117481 atatttattg tggaaggaaa aaggatttcc ggagacgcaa aaattcacga ataaatcagg
   117541 agctactaat caatcaaaac atccattggc acaacaagta gaaacttggg cagataagaa
   117601 gatgaaagct ctagatttat taggattaac aaacaaagca aaaactggta gactaattgc
   117661 tggaggatcg accgcaagaa aagatgaaga aattacacgc ccagaagtaa agccagtaga
   117721 tgaactagca gcgcacagaa ataaatggcg taagaaggca ggtgctgaaa aatgattgaa
   117781 cctggtgtaa attatgctga tttatttgca aaagaagtaa gaaagaaacc taagaagtat
   117841 cctaagaccg ttcgtttagc aatagatcgc tggtatcagt ggaaaaaaag aaaagatatt
   117901 tggtttgatg tagatcgcgc gaatgaaatg atggattggg tagaatcatt tattgttcac
   117961 acaaaaggag aaatggtggg aaaaccgttt cttttagaac cctgggaaaa atttatttat
   118021 tcttggattt atggttgggt taaagaaaat gaaaaaggcc aaattgtacg cgttactcgt
   118081 gaggcttatg tccagattcc aaaaaagaat ggtaaaacat tgattgctgt cggttcatta
   118141 ggatatgcaa tgtacggaga aggggcgtta tcagttgatt gctatgcttg cgcatctgat
   118201 tttgctcaag cgcaatatgc tgccaaacct tttgcagtta caatcttaaa caatccaatc
   118261 ctacttgaag gaactaaaat atttaggggg ccaaagggaa ctgtttctag tattacttat
   118321 gactatattc atgaagatat ggcttactca aataaattta ttgttcaaac caagaatatt
   118381 gataatatcg agggatccaa tccatatttt gtattgaacg atgaattgca taaacaggag
   118441 aaaatggaac agtatgacaa ttttaagtct gctcagatat ctttaccaca gccattgatg
   118501 tttaatatct caactgctgg gaaaggttcg tcgtctgttg gaatgcgtgt atatcgcgaa
   118561 gcaaaagaag tgttgaaacg tgatgataat gattcaaact ttgttctaat ctatgagcca
   118621 aataaaaatt atgattggac ggatagaaaa gtctgggaaa tgtgcaatcc taactgggga
   118681 atatcagtcg atttatctgc tttagaatcg gcatttaaaa cagcgcaacg gtcagctcat
   118741 tccaaagctg aatttctaac gaaacacttg gatgtatttg tgaacggcgc ggataatttc
   118801 tttgaacagg atcaagtaga gccatgttta gttaccacac aagaacttgg tgatttaagt
   118861 ggcgaaccat gttatatcgg tttagattta tcacgtacac gagatttgac ctgtgtatct
   118921 ttaaacttcc caacatggga tgaagatggt aaagcggttc ttaaagtaaa gcaactttat
   118981 tttattccga atgaagattt agagtttcga gaaaaagaag ataatgttcc ttacagtgat
   119041 ttggctgaac aaggtttcgt tgaattttgc gacggaaaaa tgattgatca agatcagatt
   119101 ttgcagtaca tagaggactg catgaattta tatgatattc agcaagtgaa ttatgatcca
   119161 gcgatgagtg acaaacttgt tgagaaatta gaaaacttag gattggaatg cgttgaagtt
   119221 gctcaatatc ctaaagtatt gaatgctcct tttgacgatg tcgaacggtt gttttatgag
   119281 aaacgaattc aatttgataa tccattattc ctttattgca ctttgaacgt tgtagcaatt
   119341 actaacatca atggacaaaa agcgccaagt aaacgtcaat caaagaaaaa gattgatggg
   119401 ttcgtggcgt ttttgtgtgg tcataaggaa acgatgaatc aaatgacaga tattgattca
   119461 gatgagttag atgattacct aagttccatc tatagataaa tagaaaggcg gtgaaaaaaa
   119521 ttgaaattac gtgatcggtt atcgaatgca gtctattctt ttatggaaaa acgtggatat
   119581 atcgaggata tttttggaca ctacacacgt tatggtcaaa gatatgtgac ggattcatct
   119641 atcatggaat cttctgatgt ttatgaatta gttcaagaca tatctaatca ggtggcattg
   119701 gccacaccaa ttgttattgg tcccgacggc aacgaagtca aagatcatca cttactaaat
   119761 attttgaaga gtcccaatga ttatttgaca ggattcgaat ttaccaaatt ggaaacaaat
   119821 actttattga tcaatggtga gacattccca ttaacggata gggatcagct tcatttggcg
   119881 tacggtgtaa caactaaaat caatgaacga cttcaagaag aatttgaaat gaatggtcaa
   119941 aaaatacctg gtcaaatgat tcgacacatt aagaacatcg gaactgattc attaaaaggt
   120001 gctggaataa ttgatcttgc aagaaacact ctagaaggcg ttctgagcgc tgaaaaagtt
   120061 ttgacggaca aatatactaa aggcggttta cttgcgttca tgcttaaact agacgcccac
   120121 atcaatccaa ataatagcgc ccaaacaaaa attgtcaaag ctatattgga tcaactggaa
   120181 ggaacgcaaa atgagagtga tcattctgtt aagatgattc ctttgggaaa aggatattcc
   120241 atcgagacat taaaaagtcc tgttgatgac gcggcaattt tgaattattt aggtgtttac
   120301 aaaaaagact taggaaaatt tctaggaatc aatgttgata cgtatcaatc gctgatgaag
   120361 acagatattg aaaaagcgat gatgtatctg cacaacaaag caatcaaacc aatattgaaa
   120421 aacaagagcg aacattacac cgctcttttt tttatgccta attctggcta tagagtggaa
   120481 tggaaaatta atattttgga ttttgttcct tactcaacaa aaacaaatat tggctacaac
   120541 atcgttcgta ccgggattac aagtccagat aacgtggcag aaatgcttgg ttttcctaaa
   120601 cagaatactc cagaaacaca agctatctat atttcaaatg acttatctag gattggccag
   120661 aaaaatgcaa cagatgattc cttaccaacg aatgatcaag acttgaaagg aggtgatgga
   120721 aatgaagaag aaggaaattc gcacgattga catcaccaat ctttcaacac gttccgatga
   120781 agaaactcat acgaggacca ttagcggcta cgctgctgta ttcaacagtc aaacactttt
   120841 atgggatgac ttaagcgaag tgattgttcc tggtgcattc tcaaaggcaa ttagtaattc
   120901 ggatgttcgt tgtttgttca atcacgattg gtccaatgtg ctaggacgta ctaaaagcgg
   120961 aacccttcgc cttgaagaag atgaacgtgg tttgaaattc gaagttgatt taccggacac
   121021 aacggtagca agggacttag ttaaatctat ggaacgagga gacatcaacc aatgtagttt
   121081 tggttttgtg ccgactgaag aaacgtggga ctacaattct gaaccaatgc ttcgaacaat
   121141 ccatgaagtg gaattatacg aggtttctat tgtgcctttg ccagcatacg aagatacaga
   121201 agctgcatta agaagtcgtg atgaattaga aaaaaacgtc gaagaaagaa aaaaattaat
   121261 caaaaaaatt aatcaagcgc tagaagcgta ggaggaaaaa tacatggata aagaattatt
   121321 gaaaaaaatg aaggcacgtc gtgagcaacg attgactgaa ttacgtgaaa aagttgaatc
   121381 aggagaatta cgcgaagcag atttagaagc cgtgaaagaa gaaattgaca gtgttattga
   121441 tgaattgaac ggaattaaag acgaattagg cgcagattct ggaactgatg aaacagacga
   121501 caatacagat gatcaatcga atagtacgga ttcagacgaa agccgttctg gtgaagacaa
   121561 cgatcaagaa gaagattcag acagtgaaga tagttcagaa aatcgttctg gaatgattac
   121621 tcaacagcaa cgagatggat tacttggatc aattaagaac ggattggagg cacgtgcaaa
   121681 aatgaccaag aaacaaaaag atcaacaact acgaaaagca tttgctaatt ttgtagctgg
   121741 aaatatttct gaagcagaag ctcgagcttt agggattgaa gctggcaacg gttcagttac
   121801 tgtcccagaa gtaattgcat ctgaagttat tacttatgct caagaagaaa atttacttcg
   121861 taaatacgga acagtggtgc gaacatcagg agatgtcaaa tatccaattc ttgtgaagaa
   121921 agcagatgcg aatgtaaaca agaaagagcg ttcaactgat attgctgaaa cagctattca
   121981 gtttgatgaa attttgctta atcctgccga attcgatgct ttggcaacag taactaaaaa
   122041 attattaaaa atgtctggtg ttccagttga agatattgtt gtggaagaat tgaaaaaagc
   122101 ttatgtgcgt aaagaaatca attatatgtt caatggtgat gacgctggaa atgaaaatcc
   122161 tggtgcatta gccaaaaagg ctgtagcatt taaaaaacct ttagatctaa ctgcttcagg
   122221 tgctgggcaa aaattatatg atgcattaat cgaatttaaa aatacaccag tgacagaagt
   122281 gatgaaaaag ggacgcttta ttattaatcg agctgctttg actgccattg aaaaaatgaa
   122341 aacagatgat ggatttcctt tgttgcggcc attcacacaa gcagaaggtg gaattggtta
   122401 ccaattagtt ggctatcctg tggattggac agatgcagca gataaaaagg gtgaaccaga
   122461 cacgccagtt ttatattttg gcgatttttc tgcatttaaa attcaagaag ttattggtgc
   122521 cttggaaatt caaaaacttg ttgaaaaatt ctctggtaaa aatcaaattg gattccaaat
   122581 ttacaacttg ctagatggtc aattggttta ttctccattt gaaccggcag tatatcgcta
   122641 cgaaattaca aaaccagttg gtggttaaga tggaagagca aactaaagaa ttgtctttag
   122701 aggaaaaatt caaatcacat attcattttg aagagggcat ggatgattct ttgctctctt
   122761 tttatttaaa tatggcaaaa gattatgtca aaacagcaac tggtggccaa caagaatatc
   122821 ttattttgat ggttgccggc attgcctatg aatatagagt ttcagaggat gaactcgaca
   122881 aagctatgaa tgccatgacg ccatttatcg tgcaaggagc gattcaaaat gccgaagaga
   122941 cagactaata atctcagatg gaaagccgaa ttgctagaca tcaaaacagg aacagacgga
   123001 aacgatcgtc caactacaat ttacgaattt aagcgtctaa tattctatga agaactcggt
   123061 gtgacttctc aagaaaaata tttatcacag caagccaaga cagacgttgt cagacgaatt
   123121 aaagtcagat gggataaatc catcacagag aaattaagtg cgctcaaaat tgattctgta
   123181 acgtataaca ttactcgcat ttatacgaat cccgatgcaa gagaaatgga gttgagttta
   123241 gcttatgtcg attagctttg atgaattgaa aacagcgctg aaatcaacaa agttagcagt
   123301 gttcagagac aaagccagat tagggacgat gtatccatac attgtgtact caaatgtgag
   123361 taacagcaaa aaaatggcat ccggtaaagt ctataaaaaa ttaccttatt accaagtctc
   123421 tttttttaca cttggaacag aacaggattt agttgttatt gaacaagcgc tgcaaaatgc
   123481 tggcattcca tattcagatt ttacaggtat acaaggtgat gagaacgacg ataccgtaac
   123541 caactattac acatatgtga ggtgtgtgga aaatgccaag taataagaat ggtttttctg
   123601 aaatatcgga ttatttagga aacctttcaa aagttgatcc gaaaaaatta tcgttggaat
   123661 ctttagaaga agcagctaac ttttatctaa agcagttgct tcctaatatt cctaagtcgc
   123721 tcttaaaaaa gaaacatatg cgcgatcaaa taaaagtagt agttgaaaac gatcaagtga
   123781 aagttcaatt tgaagagacg gccttttact ggcgctttgc cgaaaatggc acaacaaatc
   123841 aacgtgccca acattttgca agtggtacgt atgaacaaaa caaagaaaaa attgaagaaa
   123901 ttatgactag aaaaatactt gatttatggg aagggtgatt ttaattggga aaacaagata
   123961 ctttttattt tgaaggattg gacgacattt taattgcgat gatggcaacg ccagattctg
   124021 ttggaactgc accgacttat agtgaagttt tacgattgcc aattgccaca aaaatcggtg
   124081 tcaaagggaa tggaacagca ttagaaaaat gggcatccag caaaatgttt cgtcgtgtgt
   124141 cgcgagaaac aaaacatgaa cttgcgttgg atcacgtggg tattccgata gaagtgatgg
   124201 atgaaatcaa aggattagtt gctaaaagcg gagtaacgtt tagcaaaaat accgcacgag
   124261 aatttccgta cttcgccttt ggatttattg gaaatattga aaatggcggt aaaaaagcag
   124321 tttggtatcc taatacacaa ctatccaatg tgattgacga agagtatgcc actgcagagg
   124381 aagaaacaaa aattgacgat gtaactgcaa atctggtttc catcggactg aaatacaata
   124441 atgtgatgta tgcaagtttt gattcaaata gagacggagc ttctctagaa ttatttaata
   124501 aattcattgc tcaacctgta tacgatgaag aacagtggaa aacattggct aaagttggag
   124561 gtgcgggtta atggctcggt tatctgatta tggaattcac gttgaagact taaaaaattc
   124621 tgctgttgta attattcaag gcgcagaatt ccctatttca tttactatgc aaacgatgga
   124681 atttatagca gatgtgtatg gtggagatta ttcgcaattt gaatctgata tgaacgccat
   124741 gctatctaaa aaagaaggac aaatttcttc tgctaactta tcgcctagtg atctaaaaat
   124801 catgcgtgcc ttgatttatg ccatgctgcg tactggtggt ttagaggaag atccagaaac
   124861 tattttcaaa tttttgggaa tgagtggaga ggtgttgtct gcttatagta cctgtatgga
   124921 aatttttgct agccagacat ttcaggtgga agacctaaaa aaatccaaga agccacaaga
   124981 ctttcaaaaa gcgcaagcaa aaagaaagaa aaacaaaaag aatcggaaga gataggaact
   125041 ccttggagtt tttatattta cgttgctctc actctattga attggagtga gagtttcttt
   125101 ttaaagtcta cacctaactt gtggctcaaa tcttatttac agtggttaca acaaaacacc
   125161 gattttgaac cacctcaatc tgtaactatg gataaatcgc cttggtggta gaaaggagcg
   125221 ctaagataaa tggctggtaa agaatctgat gtcgttctta attttaaaac gaatggcgaa
   125281 gtcagttatt cgaaaacaat caaagaaatc aacaaagaaa tgaacttagc cgctgccgag
   125341 tacaaaaacc aagtgtctgc gatggacaag gatgcaactc aaacagaaaa attgcgagcg
   125401 gctaaacaaa aattagaaaa acaattagga ttggctgaac aacgatctca aatgctgaga
   125461 gaggaatatg aaaaatctgt caaagaaacc ggtgaatatt ctgctgaatc agaaaaactt
   125521 tataaacaat tactcaattc tgaaaccgga gaaaataaac ttcgtacagc attagaacag
   125581 acgaacgatg cacttaaaga acaaggtgac gtttctgttg atacagcaaa aaaactccag
   125641 aaaatcgaag aaacaggtga gaaagtaaaa ggcgttggtg aaaaaatgtc tgttggagta
   125701 accgcgccta ttgtagcggc aggagcagca ggacttgcag catttggtga agttgacgag
   125761 gcacttgata ccatcattac aaaaaccgga gcaacaggtg atcaagctga tagactttca
   125821 cagtctttca aaaacgttgg ttcaaatact catttacctt tacaaacggt tggggaagct
   125881 attggtgagg taaatacaca atttggattc atggataaaa aactggaaga ttcaaccaat
   125941 tatctcctac agtacgctga aatcaatgat acagatgttt cgcaatcagc aatatctgct
   126001 cgacaagcta ttgatgctta tggactagaa tatgatgatt tgaattctgt ccttgatgta
   126061 acaacgaaaa catcgcagaa tactggtcaa tctgtagacg acttgatgca aaaagcaatt
   126121 gatggcgcac cacaaattaa acaattaggg ttgagctttg gtgaaggggt cactttactt
   126181 ggacaatttg agcaatctgg tgttgattca agcgcagctt taagtagttt atctaaagca
   126241 acagtggctt atgcgaaaga cggaaaatct ttaagtcaag gactagaaga actacaagac
   126301 aaggtaaaaa atgcaggttc tgaaacagaa gccatcaatg cagcagcaga agtattcggg
   126361 actaaaggcg gtcctagaat ggccgatgca attcgtagag gtactttgaa cctggaagat
   126421 ttagcaaaaa ctgctggaga aagtggggga gctgtaggag acacattcga tgctactctc
   126481 gacccaattg atcaagccga tcaagctatg aacaatgcaa aattagcaat ggctgacgta
   126541 ggtgaagcag tccaagtaag ccttttgcct ttttttgaaa aagcaacttc cttattacag
   126601 gaattctcta aatggtgggg gtctctagat caagatacaa agaattggat cataacaatt
   126661 gctggtatag cggcagcagt tggaccagta ctaatcgttc ttggttcact tatgggatct
   126721 gttacaaaaa tcgttgggga agttaaaagt tttataggag tttggcaagg acttgctggt
   126781 ttatttggaa tgtcgggagg ctggtttgca ttagcagtta tagctattgg cgcattagtt
   126841 actggactaa tttgggcata taataacgtt aaatggtttc atgatggagt gaattctttc
   126901 ttcaaaggtg tttcagatgt agctgttgaa atatttaatt ttttaagtgg ttattttggt
   126961 ggatttttcg atggtgttat agcaaatttc aataattttt ataatgctgg aaaacgaatt
   127021 ttcagtggtt ttctagattt tatcactgga gtatttacag ggaattggtc aaaagcatgg
   127081 caaggtctag ttgatatttt tggaggtatt ttcgatggta ttgttgctgt agggaaagct
   127141 cctattaatg ccatgattgg attgatcaat ggatttattg gtggattgaa taatataaag
   127201 ataccaaaat gggttcctgg tgtaggtgga aaatcatttt ctatttcaaa actgccttat
   127261 ttagcacaag gcggtcatct aatcaatgga caagcgattg ttggtgaagc tggacctgag
   127321 ttactgactg ccaagaatgg taaaaccaca gttactccat tatcagacga agaaaaacgc
   127381 aaagggatca gtggaagagt ttctggaggt agcattgaac agcatataca cattggcaaa
   127441 gtcgatgcaa acaatccatc tgagttagat cgtatgaatc gtaaatttgc taaagcaaac
   127501 aaacaggcta ttcgtgattt gggaggtgtt cctatttgag tcgacaattt atgaatccag
   127561 atgaaccaaa ttttatttgg aaaaatcgga atgcagtaat tgatatgaat tgcatcattg
   127621 aggcagagct tccagatatt atgccgaaca agcgatacga aacttacacg attcagggcc
   127681 gaagcggaga attgacggag acgtttgatg actatgaacc ttttgatttg gaaatagaag
   127741 ggatcactat tccacattcg aaactgagag aagtcaaacg atggctcact ggtaaaagcc
   127801 aattaatcac acataatgat ccagacaagt atctagaggc tatctgcagc atggataaag
   127861 aagtcccttt cgaaaacgag tggggcttct tttatacatt cgatgttact tttcgttgtc
   127921 agccactcaa aagaaaaatc ggtgaagcac ctaaaatttt tcattctagt gttatggata
   127981 tttttgatca tggtgacgaa attgcacatc cctatctgga aatagaatcg aacggaggag
   128041 atataacgat cgctgtcggt gataaaagcc taacaatact taatacgtta gctgcaacaa
   128101 tcgtggttga tactcagctt ggaaaagcaa tacaagaagg tttgaattta tttacgcgtg
   128161 gtgattggcc agtattgcag cctgaatgga atcaggtaaa aatatccgga aaatttaaag
   128221 aagtgcggtt ttggaatagg agtgtgtatc tgtgacgcaa gaatttattt atgcttataa
   128281 aaaaatgcca gatgatttga gcgtgaacgg agcgtcgtta gttgattggg aagatttgcc
   128341 agaaatcaat cgtgtgctga atggccaata tcgtttttat ggtaactatt caagaagcgg
   128401 acagtatcgc tcttatttaa aaaaaggaaa ttttataaaa gcgaaggtac cagatggatc
   128461 atggcaatat tttgaaattt ataatgtcaa aaagaatttg acctccgttt ctgtaacagc
   128521 tcggcatatt ggttttatgg ccaataagaa ctttattgtc aagtcgttta cggataacgg
   128581 caatgggtct cagatcatga ccaatcttaa aaacagtttg gcatttgatc aaaaatttaa
   128641 ctatctttcg aatgtaggga caacgcacca atttacagca agacaagtcg cgccagttga
   128701 agcaatcatt ggttcaaata acggtaatca aaatttgact ggcgtgacta gcgcggaact
   128761 tgatatggat aactatgatt tgaaactggt aaaacagatt ggatcagata atggttttcg
   128821 gattgatttt ggcatcaatt tagaagcaat cgaagaagaa attgatgaag aatcaattgt
   128881 caatagtttg tatttggttg gcggtgttcc tgataacgat tatgatgaag acaaagaacc
   128941 tatcgaatat ggttatttag aaattgatgg agtaaccaac gagaatcgac gtattgccaa
   129001 acgtgaaaac ggagattgta aaacagttga tgaattgatc aaatggggca aaaccttatt
   129061 tgacaatgat cgtatccatg agccaaaagc tactcataca gtcagtatgg tggcgttgga
   129121 acacacactc gaatacggtg acatgtatca agagctagcg tctttacact ttggtgatgt
   129181 cgctcatgtt agggcgaaag agctagatat cgagataaaa gagcgtatgg tcgaatacac
   129241 ttatttccca acgcttggga aatataagga tattgtttta ggtaatgatt tatcactgta
   129301 cacttcggca gtaaatactc aagcacaaga attgaaaaag aaaatcgaca atcgaacaga
   129361 aacgttagtt caaaatgtgt tgaatgcgac ggcatggatc actggtaatt ctggtgggca
   129421 tgtcgttttt cgtccagaaa aagctccatc agagattctt atcatggata ctccaaatgt
   129481 ggcgaatgca aagcgagtgt ggcgttggaa tttaaatggc ttaggttatt cagacaacgg
   129541 agtaaatggc ccgttcggta ttgctatcac atcaaaagga gaaattgttg ctgacttcat
   129601 caaagtagga acaataaatg cagaagtatt cgaaacttcc tttaatgctt atggtgatgt
   129661 gttaaaactt gtaaaaggca cgcttcaaat ttggaatgaa aacaaaaaaa tcatggagct
   129721 aaccaaaaaa ggtatggaat tctggaatag aaaagaatcc attggaacga tcggaacaac
   129781 agattcagca ggaaatccat ttccaaatgc tgtaacacct acacctcttg aggaaaattc
   129841 tttggtaata cgtacaaatg gcgatggaaa atacatttta atttctccaa ctgcagaaaa
   129901 aggatttgtg ttattaggaa acggaaaagc atattatttc ggtgatttag atattcaggg
   129961 aaaacttact gttagaggta aagaagtgat accaggacaa aatggcggtc catctggcgg
   130021 aggagaaaca cctggtgggt atcctgatga attaaaaaca gatgcagaaa agagagcttg
   130081 gagaat
//
LOCUS       DACCVH010000002       106592 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.002, whole genome shotgun sequence.
ACCESSION   DACCVH010000002 DACCVH010000000
VERSION     DACCVH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.002"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1420)
                     /locus_tag="IVV98_000149"
     CDS             complement(<1..1420)
                     /locus_tag="IVV98_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP7805839.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1672..2853
                     /locus_tag="IVV98_000150"
     CDS             1672..2853
                     /locus_tag="IVV98_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7805840.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2913..4541)
                     /gene="treC"
                     /locus_tag="IVV98_000151"
     CDS             complement(2913..4541)
                     /gene="treC"
                     /locus_tag="IVV98_000151"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP7805841.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4992..7703)
                     /locus_tag="IVV98_000152"
     CDS             complement(4992..7703)
                     /locus_tag="IVV98_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP7805842.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7713..8414)
                     /locus_tag="IVV98_000153"
     CDS             complement(7713..8414)
                     /locus_tag="IVV98_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7805843.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8600..9199
                     /locus_tag="IVV98_000154"
     CDS             8600..9199
                     /locus_tag="IVV98_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7805844.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9280..10293
                     /locus_tag="IVV98_000155"
     CDS             9280..10293
                     /locus_tag="IVV98_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7805845.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10401..11318
                     /gene="rbsK"
                     /locus_tag="IVV98_000156"
     CDS             10401..11318
                     /gene="rbsK"
                     /locus_tag="IVV98_000156"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP7805846.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11346..11741
                     /gene="rbsD"
                     /locus_tag="IVV98_000157"
     CDS             11346..11741
                     /gene="rbsD"
                     /locus_tag="IVV98_000157"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP7805847.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11741..13117
                     /locus_tag="IVV98_000158"
                     /pseudo
     CDS             11741..13117
                     /locus_tag="IVV98_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            13474..15618
                     /locus_tag="IVV98_000159"
     CDS             13474..15618
                     /locus_tag="IVV98_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7805848.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15670..16710)
                     /locus_tag="IVV98_000160"
     CDS             complement(15670..16710)
                     /locus_tag="IVV98_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7805849.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16987..18789)
                     /locus_tag="IVV98_000161"
     CDS             complement(16987..18789)
                     /locus_tag="IVV98_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7805850.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18803..19555)
                     /locus_tag="IVV98_000162"
     CDS             complement(18803..19555)
                     /locus_tag="IVV98_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7805851.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19564..19926)
                     /locus_tag="IVV98_000163"
     CDS             complement(19564..19926)
                     /locus_tag="IVV98_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7805852.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20102..20974)
                     /locus_tag="IVV98_000164"
     CDS             complement(20102..20974)
                     /locus_tag="IVV98_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP7805853.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21025..21513)
                     /locus_tag="IVV98_000165"
     CDS             complement(21025..21513)
                     /locus_tag="IVV98_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP7805854.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21651..22481)
                     /locus_tag="IVV98_000166"
     CDS             complement(21651..22481)
                     /locus_tag="IVV98_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP7805855.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            complement(22497..23105)
                     /locus_tag="IVV98_000167"
     CDS             complement(22497..23105)
                     /locus_tag="IVV98_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP7805856.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23098..23415)
                     /locus_tag="IVV98_000168"
     CDS             complement(23098..23415)
                     /locus_tag="IVV98_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7805857.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23571..24299)
                     /locus_tag="IVV98_000169"
     CDS             complement(23571..24299)
                     /locus_tag="IVV98_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP7805858.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24458..25339
                     /locus_tag="IVV98_000170"
     CDS             24458..25339
                     /locus_tag="IVV98_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7805859.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25576..26619)
                     /locus_tag="IVV98_000171"
     CDS             complement(25576..26619)
                     /locus_tag="IVV98_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7805860.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26622..27290)
                     /locus_tag="IVV98_000172"
     CDS             complement(26622..27290)
                     /locus_tag="IVV98_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7805861.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27432..29768
                     /locus_tag="IVV98_000173"
     CDS             27432..29768
                     /locus_tag="IVV98_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7805862.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29883..30194)
                     /locus_tag="IVV98_000174"
     CDS             complement(29883..30194)
                     /locus_tag="IVV98_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805863.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30375..31850
                     /locus_tag="IVV98_000175"
     CDS             30375..31850
                     /locus_tag="IVV98_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP7805864.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31897..32481
                     /locus_tag="IVV98_000176"
     CDS             31897..32481
                     /locus_tag="IVV98_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP7805865.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32483..32866
                     /locus_tag="IVV98_000177"
     CDS             32483..32866
                     /locus_tag="IVV98_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP7805866.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33183..33467)
                     /locus_tag="IVV98_000178"
     CDS             complement(33183..33467)
                     /locus_tag="IVV98_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP7805867.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33819..34529)
                     /locus_tag="IVV98_000179"
     CDS             complement(33819..34529)
                     /locus_tag="IVV98_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP7805868.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34526..35998)
                     /locus_tag="IVV98_000180"
     CDS             complement(34526..35998)
                     /locus_tag="IVV98_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7805869.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36136..36609
                     /locus_tag="IVV98_000181"
     CDS             36136..36609
                     /locus_tag="IVV98_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7805870.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36762..37313)
                     /locus_tag="IVV98_000182"
     CDS             complement(36762..37313)
                     /locus_tag="IVV98_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7805871.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37418..37948
                     /locus_tag="IVV98_000183"
     CDS             37418..37948
                     /locus_tag="IVV98_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP7805872.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38431..38874)
                     /locus_tag="IVV98_000184"
     CDS             complement(38431..38874)
                     /locus_tag="IVV98_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7805873.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38890..40050)
                     /locus_tag="IVV98_000185"
     CDS             complement(38890..40050)
                     /locus_tag="IVV98_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7805874.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40557..42257
                     /locus_tag="IVV98_000186"
     CDS             40557..42257
                     /locus_tag="IVV98_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805875.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42359..43192)
                     /locus_tag="IVV98_000187"
     CDS             complement(42359..43192)
                     /locus_tag="IVV98_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP7805876.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43496..45661)
                     /locus_tag="IVV98_000188"
     CDS             complement(43496..45661)
                     /locus_tag="IVV98_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7805877.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45921..48215
                     /locus_tag="IVV98_000189"
     CDS             45921..48215
                     /locus_tag="IVV98_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP7805878.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48208..48873
                     /gene="pgmB"
                     /locus_tag="IVV98_000190"
     CDS             48208..48873
                     /gene="pgmB"
                     /locus_tag="IVV98_000190"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP7805879.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48866..49873
                     /locus_tag="IVV98_000191"
     CDS             48866..49873
                     /locus_tag="IVV98_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7805880.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49895..50914
                     /locus_tag="IVV98_000192"
     CDS             49895..50914
                     /locus_tag="IVV98_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7805881.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51195..52562)
                     /gene="nhaC"
                     /locus_tag="IVV98_000193"
     CDS             complement(51195..52562)
                     /gene="nhaC"
                     /locus_tag="IVV98_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP7805882.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52671..54092)
                     /locus_tag="IVV98_000194"
     CDS             complement(52671..54092)
                     /locus_tag="IVV98_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7805883.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54335..56212)
                     /gene="tdc"
                     /locus_tag="IVV98_000195"
     CDS             complement(54335..56212)
                     /gene="tdc"
                     /locus_tag="IVV98_000195"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP7805884.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56503..57759)
                     /locus_tag="IVV98_000196"
     CDS             complement(56503..57759)
                     /locus_tag="IVV98_000196"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP7805885.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            58339..59640
                     /locus_tag="IVV98_000197"
     CDS             58339..59640
                     /locus_tag="IVV98_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP7805886.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59709..60308)
                     /locus_tag="IVV98_000198"
     CDS             complement(59709..60308)
                     /locus_tag="IVV98_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7805887.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60562..61443
                     /locus_tag="IVV98_000199"
     CDS             60562..61443
                     /locus_tag="IVV98_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7805888.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61456..63066
                     /locus_tag="IVV98_000200"
     CDS             61456..63066
                     /locus_tag="IVV98_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP7805889.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63143..63802)
                     /locus_tag="IVV98_000201"
     CDS             complement(63143..63802)
                     /locus_tag="IVV98_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7805890.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64085..64750)
                     /locus_tag="IVV98_000202"
     CDS             complement(64085..64750)
                     /locus_tag="IVV98_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805891.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(64897..65502)
                     /gene="dhaL"
                     /locus_tag="IVV98_000203"
     CDS             complement(64897..65502)
                     /gene="dhaL"
                     /locus_tag="IVV98_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP7805892.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(65530..66513)
                     /gene="dhaK"
                     /locus_tag="IVV98_000204"
     CDS             complement(65530..66513)
                     /gene="dhaK"
                     /locus_tag="IVV98_000204"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP7805893.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(66515..66910)
                     /gene="dhaM"
                     /locus_tag="IVV98_000205"
     CDS             complement(66515..66910)
                     /gene="dhaM"
                     /locus_tag="IVV98_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP7805894.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            67064..67384
                     /locus_tag="IVV98_000206"
     CDS             67064..67384
                     /locus_tag="IVV98_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP7805895.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(67496..68365)
                     /locus_tag="IVV98_000207"
     CDS             complement(67496..68365)
                     /locus_tag="IVV98_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7805896.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(68461..69765)
                     /locus_tag="IVV98_000208"
     CDS             complement(68461..69765)
                     /locus_tag="IVV98_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7805897.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(69762..70271)
                     /locus_tag="IVV98_000209"
     CDS             complement(69762..70271)
                     /locus_tag="IVV98_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805898.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(70446..72581)
                     /locus_tag="IVV98_000210"
     CDS             complement(70446..72581)
                     /locus_tag="IVV98_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7805899.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(72664..74319)
                     /locus_tag="IVV98_000211"
     CDS             complement(72664..74319)
                     /locus_tag="IVV98_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7805900.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(74321..74635)
                     /locus_tag="IVV98_000212"
     CDS             complement(74321..74635)
                     /locus_tag="IVV98_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7805901.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            74805..75065
                     /locus_tag="IVV98_000213"
     CDS             74805..75065
                     /locus_tag="IVV98_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP7805902.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            75079..75393
                     /locus_tag="IVV98_000214"
     CDS             75079..75393
                     /locus_tag="IVV98_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP7805903.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(76123..76677)
                     /locus_tag="IVV98_000215"
     CDS             complement(76123..76677)
                     /locus_tag="IVV98_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP7805904.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(76803..78732)
                     /locus_tag="IVV98_000216"
                     /pseudo
     CDS             complement(76803..78732)
                     /locus_tag="IVV98_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(79038..79754)
                     /locus_tag="IVV98_000217"
     CDS             complement(79038..79754)
                     /locus_tag="IVV98_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP7805905.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(79755..81578)
                     /gene="glpO"
                     /locus_tag="IVV98_000218"
     CDS             complement(79755..81578)
                     /gene="glpO"
                     /locus_tag="IVV98_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP7805906.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(81592..83088)
                     /gene="glpK"
                     /locus_tag="IVV98_000219"
     CDS             complement(81592..83088)
                     /gene="glpK"
                     /locus_tag="IVV98_000219"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP7805907.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(83224..84684)
                     /locus_tag="IVV98_000220"
     CDS             complement(83224..84684)
                     /locus_tag="IVV98_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7805908.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(84674..85969)
                     /locus_tag="IVV98_000221"
     CDS             complement(84674..85969)
                     /locus_tag="IVV98_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7805909.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(86301..86978)
                     /locus_tag="IVV98_000222"
     CDS             complement(86301..86978)
                     /locus_tag="IVV98_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP7805910.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(87008..88099)
                     /locus_tag="IVV98_000223"
     CDS             complement(87008..88099)
                     /locus_tag="IVV98_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP7805911.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(88200..88634)
                     /locus_tag="IVV98_000224"
     CDS             complement(88200..88634)
                     /locus_tag="IVV98_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7805912.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(89218..90675)
                     /gene="ascB"
                     /locus_tag="IVV98_000225"
     CDS             complement(89218..90675)
                     /gene="ascB"
                     /locus_tag="IVV98_000225"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7805913.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(90672..92567)
                     /locus_tag="IVV98_000226"
     CDS             complement(90672..92567)
                     /locus_tag="IVV98_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7805914.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(92625..94400)
                     /locus_tag="IVV98_000227"
     CDS             complement(92625..94400)
                     /locus_tag="IVV98_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7805915.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(94450..95946)
                     /locus_tag="IVV98_000228"
     CDS             complement(94450..95946)
                     /locus_tag="IVV98_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7805916.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(96140..97762)
                     /locus_tag="IVV98_000229"
     CDS             complement(96140..97762)
                     /locus_tag="IVV98_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP7805917.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(98090..99403)
                     /locus_tag="IVV98_000230"
     CDS             complement(98090..99403)
                     /locus_tag="IVV98_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP7805918.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(99648..99872)
                     /locus_tag="IVV98_000231"
     CDS             complement(99648..99872)
                     /locus_tag="IVV98_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805919.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(99892..100260)
                     /locus_tag="IVV98_000232"
     CDS             complement(99892..100260)
                     /locus_tag="IVV98_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7805920.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(100456..101166)
                     /locus_tag="IVV98_000233"
     CDS             complement(100456..101166)
                     /locus_tag="IVV98_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805921.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(101184..101681)
                     /locus_tag="IVV98_000234"
     CDS             complement(101184..101681)
                     /locus_tag="IVV98_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7805922.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(101718..102170)
                     /locus_tag="IVV98_000235"
     CDS             complement(101718..102170)
                     /locus_tag="IVV98_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7805923.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(102305..102910)
                     /locus_tag="IVV98_000236"
     CDS             complement(102305..102910)
                     /locus_tag="IVV98_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP7805924.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(103360..103980)
                     /locus_tag="IVV98_000237"
     CDS             complement(103360..103980)
                     /locus_tag="IVV98_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7805925.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(103982..104851)
                     /locus_tag="IVV98_000238"
     CDS             complement(103982..104851)
                     /locus_tag="IVV98_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP7805926.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(104874..105281)
                     /locus_tag="IVV98_000239"
     CDS             complement(104874..105281)
                     /locus_tag="IVV98_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP7805927.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(105300..106589)
                     /locus_tag="IVV98_000240"
     CDS             complement(105300..106589)
                     /locus_tag="IVV98_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7805928.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        31217 a        22201 c        18727 g        34447 t
ORIGIN      
        1 ttcctgcata taaatgaaaa tgttcggagt cagccggtgc aatcgtgtga tcactgaatt
       61 gaatatatct aaaagcgcca ctttccttat cttctgcttc gaatagatac cttacgccac
      121 ggtttcctgc ctcgtaggtc aagatttctt tccctacata acgataattt gaacgtttcg
      181 ttgttccatt cttaaacgta aatgccatct ctttctcact gatcttgatt gaagcaatat
      241 ctgtttgata gcccttcgta taatattctt tatattcttg tgctgtctta tcctgattca
      301 atttttcttt atattcaaaa acaggatcaa aagtcccatc ttctacatac gtatctactg
      361 tttgccaagt tcctgcccaa tctgaaagag agcgatcttg tacatcctcg tcttcaaaat
      421 aaccgttgta gacgctcttt tcttttttgg gggtcaaagt atcttctagc gggttttctg
      481 tctctgtcgt ttttttcaac gcttcgaggt ttgcttccat gatagaaaga tagttttctc
      541 cattttctat ttgttcattc gtcaatcctt ccaaaggatt caatacttct aaagatacac
      601 ctgcttcgtt tgctaacgtt ctggcaatac tatctttggc gttttcttca aaataaatat
      661 agttgattcc atgttcttta acaaagtgtt tcagttcagc aattctcgcc gcagacggtt
      721 cttcactaga agaaagacca gcaatcgata cttgattcaa tccatattct aacgctagat
      781 agttgaatgc agcatgttgc gtgacaaaag atctttgttt tgcttgctta aaggtttctt
      841 gataaagctg atggagtgct tgaagtttct cggtataggc tgctgcattt tttgtccata
      901 cttcctgttt ttctgggtaa gcttcaatca gctgatcacg tatgtttgct acctgcttga
      961 ttgctaaact tggagctagc catacatgtg ggtctagctc atgtgtatgg ccttcttccc
     1021 cgtgttcatg gtcatgatca tgtccttctt cacttcccgg aagtaaaagc ataccttctg
     1081 tcgcttttat cgtatggaca ttgccttctt gtaatgtttt ttggattgcg gggacccatg
     1141 tttccatgtt ttcatcatta taaacaaaga tatctgtatc ttggatcttt gccatgtctt
     1201 tagcagaagg ttcataatcg tgggaatcag tccctgctgg aatcaataac tctacttctc
     1261 cttcatcccc gacgattgct tttgtaaaat catacatggg ataaaaggtc gtcatcacgc
     1321 tcaatttttc tttactgtcc tcggctttcc cacttgcccc gcaagcagtt aacatacctg
     1381 ctaaaaccag catggccaat atacctatca atcgtttcat ttatgacact cctcttctca
     1441 tcttctttca tttgaatgtt ccgattcgct tttcgcaaac cgtaatagtt acgttttagc
     1501 aacaggattt aatttatcat atggttaaaa gaactgtcaa gcgttttctt attttaattg
     1561 atgagaaagt ttatatgaat gattgacgat atttttgcaa tcaacctcta tcattttcct
     1621 tttatacccg cttttgtcta taatgaagtt atagataaag gaggaaaaag agtgaaaaaa
     1681 gaaacagata caacgaatcg tttgatccgc tttttaggag gaaaaacctc ttactatgtt
     1741 ttaggaatag ttatcttact tgcgctgatc atttattttt tccatcagat ctcgtttata
     1801 ttcaagcctg tcggaatcat tatcgctact atcttgcccc cattattgtt tgcactgatc
     1861 ttgtattatc ttttggaacc agtcatcaaa cgtttgagca agcacctttc gaggaacttg
     1921 tcagtcatta tcgtttatgt gattatttta tttttattgg ggcttggaag catatggctt
     1981 attccttttc ttgaagaaca ggcaaagaca ttgatcagta gtttgccaga tttgtttcaa
     2041 gattttcaag agagtctccg acaatttttg gagaaaacac cttttgccga ttcatttaat
     2101 caatttttcg cttctattga cgacgtgacg tctgatatag ctggatttat tggaaattat
     2161 tgggaaagtg gcgcacaacg gatcagcaac attttttcaa ctgttacagc tatttttatt
     2221 actttattta ctggtccaat tgtcgctttt ttccttttga gagatcctca aaaattttat
     2281 cagtcagttt tagcgattgt cccaccagca tttcgtacag attttaaaaa tttgacaaag
     2341 attgctaatc aacaattggg ttcatttcta aaggggcaaa tcattgcttc atttatcctt
     2401 ggagcagtct actgggtttg tttcttactg atcggattag aatttgctag tgttttagct
     2461 atttctgctg ggttgttatg tatcattcca tatattgggc cgtttatcgc cttctttcca
     2521 ggtttgatca ttgcattcca agactctact tttatggctg tcaaatttgt cattgtctgg
     2581 tttgccgtac aacttctcca cggtgacttg gtgattcctc gagtaatggg tgatcgttta
     2641 cagatccatc cgattacgat cttaatcgtt ttacttgtca tgggtgatct aatgggaatt
     2701 gtgggcgtta tttttggtat tcctatctat acgttagtca aattactcgt tacttttatt
     2761 ttccgtaaat tcaaacaacg ctacaataaa ttttatggcg ataaaggaga gtatgaaaac
     2821 tcttcatttt ctgaagaaga ttattttaaa taaaacacaa aacgtcgatc ttacgagaat
     2881 agctcgtagg aacgacgttt tgtgtttttg ttttaatttt tcagcaaagc aattgcctgg
     2941 tatggtttta gctccagact ttgatgaaga acagtatcgg aataattatc gataagaata
     3001 ttggcttctg tgaatccttc tgggatggcg atccttgtat ctttatcata gaaatttgtt
     3061 aatacaagca gctgctgtcc ttcaaattgg cgaagaaagc cataaacttc cggatgattt
     3121 gcttcataag catgataatc tccttgtgca acgattggat atgtttttct cagccgaatc
     3181 aatttcttgt aataggacaa aatagaatct tcagaagata gttctttttc tacattaatc
     3241 tcttctagct tgcctccaac ttttaaccaa ggtttccctg tagtaaatcc tgcttgttct
     3301 gtgtctgacc attgcatggg tgttcgagag ttatcgcgag attttgcttt gatccgacga
     3361 aacgcttctt tttctgtgaa tccttgttca aggagtaact tataagcatt caaactttct
     3421 acgtcaatat agtcggaaat cgatgaatag tctgggtcga tcatgccgat ttcttctccc
     3481 atataaatat agggcgtccc acggttcaaa tggatcatgg ttgctagcat ctctgctcct
     3541 tgttttcgat actgatcgat agctacaaat cgattgagcg cacgtggctg atcatgatta
     3601 ttaaaaaata gagcattcca gccgttaccc tcactcatct tttctcccca tgtatgaaat
     3661 agtcgcttta attctgcaaa atcaaatgga ggagtagacc atttattccc attttcataa
     3721 tcgactttca aatgatggaa attaaagacc attgataatt cttctctact aggttctgta
     3781 tacaagatac aattttcgat cgtcgtagag ctcatttcac cgactgtgat gatagtggaa
     3841 tccgtcccaa acgttgcttg gttcaattct tttagatacg tatgggtgat tggtttgtcc
     3901 gtatattcag gtttgccatc attttcttta ttatttttca attgttcgtc tttaccgata
     3961 acattgataa catcgaaacg gaatcctttt accccttttt ccatccaaaa acgaacaact
     4021 ttgaatagtt cctctcttac tgcttggttc cgccagttca agtcagcttg tgtccgatca
     4081 tataagtgca aataatattt ccccgtatct ccaaatggcg accaagcact tccaccaaat
     4141 tttgataccc aatccgttgg ctcttctctt aaaatgaaga agtcctgata atgctggtcc
     4201 cctgctagtg cttttttgaa ccattcatgt tctgtcgaaa cgtgattcag caccatatcg
     4261 agcatgattt ctatccggta tttctttgct tcggctatta gctgttcgaa ttcctccatc
     4321 gtaccaaaga taggatcgat ggctgtgtaa tcagagatat cataaccgtt gtctttttga
     4381 gggcttggat aaatagggtt tagccaaatc atgtcgatgc ctagatcatt cagatacggg
     4441 agtttttctt tgattccttt taaatctcca attccatcac cattactgtc tttgtaagat
     4501 ttgggataga tttggtaaat gactttgtct ttaaatgtca tggatattta cctccattca
     4561 actgatttat tacctaccac aacttatata tacaagttat catttattat tataactgaa
     4621 ccgaaagcgt ttgtaaaatt tatctttata cattctaaga ggtctgttgc ccaataaaaa
     4681 acaagagatc agacatgtat ttgtctatcc tcttgtttaa aatagcaaaa tattcttgtt
     4741 tcttctataa atggtgttca aaagctttta tctacggcaa tcagtcttct caaatgtaaa
     4801 acatgaggag ctaattttat ttgagtattc tttttgctcg atgcaggacg gcttttttac
     4861 aacctctgat tcatggtgtt caatcagctg tccttcggta ttagctcaaa aaacggcaaa
     4921 atatgaaaaa ctattttgcc gtttgtttct ctaatactca ggtcaaaccg ctgatttcac
     4981 aacctctgtt tttattcatt cgatttcaac gcatcaatca tatcgatatg ctttaatttg
     5041 aaatgggtaa caatcatcac aataaccgta aatacgatag ttaatcctgc tgataagaca
     5101 taagcccacc atgtgatcac taatggaaag atgacattct ccatagacgc ttgttgcaag
     5161 atgaagtcag tcaatatata tcctacacca aatcctccga tgattcctaa aagagtaaag
     5221 atgatatttt ctcgaacaat gtacatcgtg acttctttat caaaaaatcc aaggactttt
     5281 attgtagata attcgcgtac acgctcggaa atattgatat tagttagatt atacaagacg
     5341 ataaaagcca gcagtcctga taatacgaca aagattaaga caaccgagtc taagttcgcc
     5401 attgattctt cttgcgtttc gatttgtttg gacatgaaag acgtatttgt cacagcgtct
     5461 gtggcaagca gtttctcgga aagcatttct tcttcttttg ttgtcatctt atctgtacgc
     5521 agcaaaaatg cattatccat catcgattga tcagtaactg aagcataata ttcaggggac
     5581 atataaataa agctacctag atagtttttc acgatttctt ttacttcgac tttccattct
     5641 ttttgatctt catcataaag cgaaatatga tctcctgtag ataagtcaaa tagttctgct
     5701 actttttgcg taatagcgat tcctgtttta ggcaaggagc gtgggttctc ttcaagatca
     5761 gttaaatgga taaaacgatc caaatcagct gttttacttg gtacgatcac tgtcagactt
     5821 tgcgaagcat gtcctttttt tctcaattct acggtttgag tatgaatagc taggatctca
     5881 tttacttttt cttgcttctg cagcatatcc gctgcttttt gacgactatc ttccgtggat
     5941 gaatccaatg taacgattgc ttgatagtca atgatcggtc caaattgttt ggctgaaaca
     6001 gaacttagag aatctttcaa tcccacgcct gcaaccatca gcccggcaca tccagcaatt
     6061 ccgataatcg ccataagcat tcttgactta tatcggaaga gatttcggta actgattttt
     6121 tgattaaagc taaggcgtga ccacagcgga gtgatgtatt caagaaaaat gcgtttccct
     6181 ggcttcggtg ctttcggttg aagcaatgca gcaggccgtt ctcttaaatc tttgaataaa
     6241 acgatcattg cagcgccaaa tgcggcaatg aagaatgcgg cagctgcttg taaaatcggc
     6301 ggccagtcat aaaaaataag cgcactccca atatcatacc gctcgttaga cagctcaaaa
     6361 atgatccttg gcaaaagatt cgttcctaat atcgttccta aaacaatacc tatccctgag
     6421 gctagacttg catagattgc atattttttt gcgatttcaa ctttcgtata acctaacgcc
     6481 tttaatgtcc cgatttccct gcggttttct tctaccatac gtgtcattgt cgtaaaggtg
     6541 atcaatgcgg caataaagaa aaagaaaaca ggaaaaacat tggcaatcgc agcgatacga
     6601 tcagacagat caccaaattc ttgaaaaccg acattttctg aacgttcatt gtataggtat
     6661 gatggtttag ttaaattttc aattttttct gcatttcgat tcaattcttc ctctgcagag
     6721 gccagttcac gttctttctc aactaattgc ctttcttgtt cagcaagttg agcttcttgt
     6781 tgagataatg tttgaacagc gattgttcgt tgcgcttcag gaagctgctg gatagttgct
     6841 gactgttgcg ctaactgttt tttagcatct tctaaccgtg ttcttgcttg cgttgtttgt
     6901 gctttgccat ccgctatttt ttgctgtgcc ggttctaatt cttcgttggc cgattttttc
     6961 agctcttcta agcgttcttc gggtcgatct tgtaaatact tttctgcctt ttcttgattt
     7021 tgctccattt tatctttgta agctttgctg tacgtattca aattctttac gtttgtaaaa
     7081 tcaagatata agacagaata aatatctgtt ttaaaaacgg attcaggtaa atagacaaaa
     7141 taatcgacgc taccatttcc gacgttcgcg tatcctctct ccaaattgtt gatgaacaat
     7201 ggagaacgga caaagcccgt gatggtatac tctttttctt tcaattcatc tgaatcaatc
     7261 tgataaatat caccgatttt atacccttca tcttccgctt tttcatccaa tacaagctgg
     7321 tttggttttt ccgggagttt tccatcagtt aattgtagct tgttctgctt gttatttttg
     7381 ttataagaaa atatttgaat cacttcgttt ttgccagtat tggaataata gatctgtttt
     7441 cctgtttcta cttttgcatc tgggatcttt tctgcttgag caatatcttt ttgtgtcaag
     7501 ccaccagtag aaacgatttg caaatcagaa agtcctgctg taccaacata gtgatccatc
     7561 gttttttgca tgacaggtcc agcagttttg acacctacaa ataaaagtgt tcctagcatg
     7621 acaataagga tgattgcaat gaatcgtcct ttagattgcc gaatttcgcg aaaacctgct
     7681 ttaagatatg ttcttgtttt cataaaatcc ccctaccata caatctcatc aatggatgaa
     7741 ggatgatcat ttaattcaac agaccttact ttagcatcat taatgtgaat gactctatca
     7801 gcgatgggcg ctaaagcaga attatgtgta atgatcaaaa cggtattgcc gtgttgtctg
     7861 ctagcgtttt gcaataattt caatacttgc ttgcccgttt caaaatccag cgcgcctgtc
     7921 ggttcatcac ataaaagaag tttgggattt ttagctagtg cacgagcaat tgaaaccctc
     7981 tgctgttcgc ctcctgataa ttgggacgga aagttattca atcgatgagc taggcccact
     8041 tgcctcaata cctctacagg atcaagcgca tcaggagaaa cttccgttgc caattccaca
     8101 ttttcttttg ctgttagatt aggaacgaga ttgtagaatt ggaaaacgaa ccctacatct
     8161 gttcgtcggt aagcagtaag ctgtttatct gaaaattgcg caatatctgt gtcatcaata
     8221 atgatctgac cttcatcagg tgtatccatc ccacctaaaa tattaagaat cgttgacttt
     8281 cctgctccac ttggaccaag tataatcact aattcgcctt tttcaattga aaaagaaata
     8341 tcgtcatttg ctgtaatggt cgtttctccc attttgtatc gtttgtattc attttttact
     8401 tcgacatact tcactctgat tcctccattt tcacgatatt tctcgctata tctatgcatc
     8461 gaatgcgttt tctcacactt atttatttta ccactgaatt tctctagact aaagaaagga
     8521 atcctttaat ttagttgaca aataaacgat ttatgattta cttacataaa aaacattgtt
     8581 atttgaaaga aggaacatca tgaatgattt aaaggaaaat atgatttttg atttatcaaa
     8641 aactgctttt gtcgcgatcg acatgcaaaa agagatcgta aataacggta cactctctcc
     8701 acacactgca gcatctattc tgacaaacaa tgatttgtta gtaagaacat tgaaacgtac
     8761 cgctgccttg aaagttttag tgaacgtaga catctccact ttcccttatt tgagtcaaca
     8821 aactgatatg ggtggaatga ctgcttctgt acctccagaa ttcactgatt tacttttgaa
     8881 ggattctttg aaagatacag ataatatgtt gactatcaca aaatacaatc caagtgcttt
     8941 ttttggtact tctcttgatc ttcaacttcg ccggcgtgga atcgaaacta tcattttaag
     9001 cggtgtagcg acaacaaacg gtgtatatgc tactgcatta gatgcctttc aacacgggta
     9061 ccatatcgtg cttgctgaag atgcttgcag tgatcgtgac aaagaatccc atcaattgtt
     9121 cataaaaaag atatttccga aaactgcacg agtacgctca acgaaacaaa taatcgaagc
     9181 tatccaacaa agcaaataag tactggcaca cgtgattttc atttacttct ttttgatttc
     9241 atgggaaaat aaccacagga tttagatagg agtatgaaca tggtgaaaaa aaagatcaca
     9301 atcaaagaag tcgctaaact ttccggcgtt tcaatcacaa ctgtctcctt gatattaaat
     9361 ggaaatacgg agaaattcag tccgaaaact gttcagaaag ttttagctgc caaagaagaa
     9421 ttaggctatc agcctgacta ttttgctaga caaatgatta ccaaggaaac gaaaacaatt
     9481 ggtgtactcg ttcctgatat cacgaatcca ttcttcagta cactgatgcg aggaattgag
     9541 gatatcttgt ataagcagaa tttcgtcacg atattatgta atgctgattc tgatcatcaa
     9601 aaagaaatcg aatatctagc cgagctcaca cgtcgaggtg tggatggatt cattatcgcg
     9661 acttctgctg tctctacaga tgcaatcaac gaaaatttga aaaaacaagg ccggcccttc
     9721 attgttttgg atcagaaaaa atctgaagga tttagtgatg ccgtacgaac agacgatttt
     9781 cgcggtggtt acctagcggg catgcacttg cttagtctag gacatcaaac gatcgccctt
     9841 gtctatcctg aaaatccacc ggaaaatgtc cacgctcgga ttgaggggtt taaatctgct
     9901 cttgatgttt accaaatccc tcacgaccaa ctgatcctct tacctacaca gttctcaaaa
     9961 caaggtggct accagatcac agcagaactt cttgattctg ctgcaactgg tgtgtttgct
    10021 ttaaatgatg aattagcttt tggattatat cgcggattag aggaagctgg aaaaagcatc
    10081 cctgaagact acagcattat tggctatgat aatatagata tgtgcgagta tatcaagccg
    10141 aaactgacaa cgatcgcaca accaatcttc gaattgggac aaacatctgc caagttattg
    10201 ttagatcgga tccaattccc agaaaaagaa tgggaagaaa aaagattacc tgtacgatta
    10261 gaaaaaagat tttcaactgc acccttgaaa tagctttcaa ggtgtgctat atttttatcg
    10321 aactattaaa acgttttact aaaacgtttt aaaaaataat tttcccatca aaataaatga
    10381 gatagttgga ggtttgtaaa atgaacacgg ttacagtaat tggaagtatt aatatggaca
    10441 ctacccttcg tttaaccaac atgcccaagc caggcgaaac gatgcatgcg catgagattt
    10501 ttcacgctgg cggaggtaaa ggtgccaacc aagcagtggc agccaaacgt tcaggcgcac
    10561 ggacatcttt tattggaggc gttggggctg acagcgaagg acaacagtta ttagatctac
    10621 tgacaaaaga aaacatcgat acatctggga tagctgaaat ccaaggcgcc acaaccggac
    10681 aagcaatgat tatggtagac gcagcaggag aaaatagtat cttgatccat gcaggggcaa
    10741 ataatgcttt ccatgaacaa gaagtcctaa aaaacaagca actgattaca aacagtgact
    10801 ttattattgc tcagtttgaa agtagcttag atgcgacgat cctagctttt tctattgcaa
    10861 aagacgcagg aaaaacaacg atcctgaatc ctgcaccagc tcgtgaaacg attcctactg
    10921 aactacttga aaagacagat atcattatac caaatgaaac agaaacagaa atcattacag
    10981 gaatcagagt gacagatcat aacagtttgg tcgcagcagc cgaaaaactc catgaattag
    11041 gtattggaac agtaatcatt acactaggca gtgccggcgc tttctatcat acagaaaaag
    11101 aacacggtat cgtccctgct tttaaagtgg atgccgttga cacaacagcc gcaggtgata
    11161 catttattgg cgcattaagc agcacacttc agccagacct tagtaacttg aaagaagcga
    11221 tcctttatgg aaatctagcc tcttctgttg ctgtgcagtc ttatggtgcg caaccttcta
    11281 tcccttaccg cgaagcttta gaacaatcag cagtctaaaa ttaacaatga gaggaagaaa
    11341 caaacatgaa aaaaggaaaa gtaatcaatt cagatatttc acgagtaatc gcacaaatgg
    11401 ggcactttga taaattaagt atcggggatg caggcatgcc tgtccccttt ggtactgaaa
    11461 aaatagattt ggctgtctca aacggtcttc caagtttttt atctgtttta gaaaacgttt
    11521 tagaagaact tgaggtacaa tcgattgaat tggcggaaga aataaagaca atgaacccgg
    11581 aaatattgga aaaaatcaaa ttattgttac cagatacacc gattagcttt atcccacatg
    11641 aagaaatgaa aaaagagttg aataactgtc atgcatttat tcgtacaggc gaaatgacac
    11701 cttacgccaa tattatatta gtgagtggag tggtcttcta atggaaacga caatgaatcc
    11761 tgaacagatg gtactgtccg agcagattca tatgctgatt gaacagttgg gaggaaaaga
    11821 caatattgat tctgtccttc catgtgcgac tcggcttcgt atcaaattga aaaaacagcc
    11881 agtagccaat gcagaaaaat taaaacagca aatcccttcc attaagtatt tcattttact
    11941 cgatagatat gcagaaataa tcatggatca gggattggct cctgcttaca aggaattgac
    12001 gcgtcaaatc gatcattcag ctccgaaaga aaagctaaat ccgatcgaaa aactatttgg
    12061 tttgatatcg gaaatcttta cgccgatcat tccgctgttt gccggttctg gtatattaaa
    12121 aggtctggtt gttttagcga ctacgattgg ctggcttagt gaaacaagcg gaacttatca
    12181 tattttgtct gctgcgtcga atgccgtctt ttattttctg ccaatctttc ttgctttttc
    12241 tgctgccaaa acgtttaaag tgaatggata tattgcggct gtcattgctg cagcactgat
    12301 tgaaccgaat ctgacctctt tactttcaga cagtggcaaa gcagctactg attttctggg
    12361 gattcctgta gtactgatgc agtagtatac gtctactgtc atgccggcga ttttaggtat
    12421 tttcttttat tcttttgttg aaaaattcct caaaaaatat attcgcgaaa atatgcaatt
    12481 agtatttgta cctttacttt cattagttat cacggttcct ttgacgttaa tggtattcgg
    12541 gcctgcgggt gtttaccttg gcgaaggttt agctgccgca attacttgga tgatggatat
    12601 taacggaccg atcagtggcg caatcatcgc tggtggttgg aatattttgg taatatttgg
    12661 tatccaatgg gctgtaaacc ctgtcatgat cagtaatatc tctgcttatg ggttcgaccg
    12721 aatcgttccg ttgacaggag cagccaattt tggaatggct ggtgcagctt taggtgtatt
    12781 tctgcgaagt aaacgttcaa aaacccgttc gatctccggt tctgcttttg cttcgatttt
    12841 acttgcggga gtgaccgaac caactgttta cggaattgcg atcccattga aaaaaccatt
    12901 tgttgctgct tgcattggtg cagctgctgg tggagctgta atgggatttg cccaagtgaa
    12961 agcgatcgct tttgtatttg gtagtctgac cacattgcct gcattcattt ccggtacttt
    13021 tttctggtac ttagcaggac tggctgttag tctagtcgta gcaatgatca ctactctcgt
    13081 tagcgggttt gatgaagacc taatgtctta tgaatagtta atgaaaaaga ctgaagtatg
    13141 agatgtttat cacatatttc agtctttttc tttttaggat cattattttt ataaattttt
    13201 gtgatacttt ccaaactttg gtataattta catatgcata accattttta tccccacttg
    13261 tttatcccca aacaaaggtg gtctatgcaa taaaatgaac gtcaaagaaa aacgaatgaa
    13321 tgctcgttgc ttatttacaa attgttttat ttagaataca cagacagatt tatgaaaaga
    13381 aaaagctttt cgacacgatt atctgttcca aaaaatgtct aatgaatgct gaataagaca
    13441 gaaaatcaat gaaaggaaaa ggactagttt attatgaaaa ataaaaaaac gatacgtttg
    13501 ctagctgcta cttggctgat tgctccgtct gttttgtcga ccaataccgt atttgccgta
    13561 gataatcaaa tagctgatca aacagtcaca acagatacga ctacatccag ctcagctact
    13621 agtgaaacaa cggattcttt tacagaagac ccaactggaa caactaactc aacaacagga
    13681 tcgaccgagc caactgaaat tgatccggct gatccatcag aaaatgaaaa gccagccgag
    13741 acatattccc ttacaattgc tccttctttg attggtaaga tccaactgac tgcttcgaca
    13801 gcggattccc ctgaacagca acctttggat attacggaaa gtggaacggt agaaggttta
    13861 ttagcggaaa cgaaggtaac ttacactatt acgccagctg aaggtgaaca aattgcttca
    13921 gtcgctgtta atggtgccaa agaagtaaat tatgatgcaa agacctttac agtaggtacg
    13981 aacaatttat ctattactgc agaatttaaa gctggaccgg atacttcaac agagaaacca
    14041 actgatccta gtgaagaagt ccctagtaca ccagatccgg aaacgccaaa caaaccagat
    14101 gtgggtaata acaacaataa taatggttca aataattcaa acaataataa caataattcg
    14161 aacagcggga attcttcgaa tcaaacaaac ccatctggat cgaataacaa tggaaatact
    14221 cagagagaac caaaccatcc aaacaatggt tcatcgaatg gcggaacgaa caatgcttca
    14281 tctcgtccaa atacagcaaa tcaaagcggt atagagaatc catcttctgc ttcttctgat
    14341 tttgttgtaa aatcaccaat tgatgctgta ttgcctacaa atacaacgaa tgtccaacaa
    14401 gcaatcgttc gagaagcatt caagcatctt ggaaaaccat atgtatgggg agcaaaaggt
    14461 ccaaatactt ttgactgttc tggtttgact tattacgtat atatgaaagc aaccggtcat
    14521 tatatcggtg gctggacagg cgaacagcaa tatgcaggta cgcagattcc agtaagtcag
    14581 gcccaacctg gcgacctcgt cttctgggga ccttcttccg gtgttactca ccatgtaggt
    14641 atctatattg ggaacggaca atttatccat gcgcctcaac caggagataa agttcgagta
    14701 acttctattt cagatttcac gcctgatttt gctgtccgag taaacttagc aggtttacct
    14761 gctgcttcag gttcgctgac aggcggctca tctattttag atggattaga tggctcgttc
    14821 catttcagtc aaaaccaaac aactgatcag ttcttgaaaa agattgcaga tgatgcacag
    14881 gaaatcgggc aaaaagaagg aatctacgca tcagtcatga tggctcaagc tatccttgaa
    14941 agtggatctg gaaacagctt attatcaagc gaaccaaatc ataacctttt tggtatcaaa
    15001 ggatcatata aaggaagcag cgtgaccttc aatacacttg aacaagatag ttccggacaa
    15061 agctaccaaa tccgcgcaca attccgtaaa tatccttctt acaaggaaag tttggaagac
    15121 tatgccgact tgatcaaaaa tggactgact ggcaatcctg atttctacaa accaacttgg
    15181 aagtcggaaa caaaagacta caaagaagca accaaatatt tggaaggacg ttatgctaca
    15241 gatcgccaat attcacaaaa attgaacgcg atcatcgaag cgtacgacct gacaaaatat
    15301 gatgaaccga aaaaagaagc agcaacaact gaagaagcaa acgctgaaat cctcaatatg
    15361 tctaagcgat tcgatgtgcc aatcaaatgg acaacagatg gcgtgccaat cacaggatta
    15421 gaattttcaa cgataaaacg cgtcaacaac gcttcttcca tcttccgtgt cgcttcaatc
    15481 tgggatttgt ggaacaattt tacggcaaga cagataccag aaacaactac tcgtacagtt
    15541 aaagctgcaa ctgttcctgt actaaccttg ttaaggttag acaaatcatt ctggcttgat
    15601 ctgcctttaa agaaatagaa taaattaaaa aggggatgtg acactgtcac actccctttt
    15661 taatttattc tatttcttta tatttatttt gtattccgtt acaaactcgc gtacttggtt
    15721 aggttccaga gtgacatctc caaaactttc aagtcgctcc gctcctggca gttcttgagt
    15781 ctcaaatgtg ataccgccat gatttactaa tttattcccg cgcatttccg gtccatcttc
    15841 tccaaaattt gctgtaaaaa tcacgattcc tgaagcatct gtttttactt ggatcgatac
    15901 tttttcatct gggcttgtca attccgcagc atttagtaaa ccagattgtt ttttcaacaa
    15961 aaatggatga tcgatgccgc ccactatcat tgattggcga aaatcactgg caaagacctc
    16021 acctaatttt ttaggacgtt ggaagtcaaa tgctgtgcca cttactgaaa ctacttctcc
    16081 tgtaggcgtt gtatctttat tgagcgtagc aaataatcgg ctattcaacc aaagtatatg
    16141 ttcgtcgatt gactgtgctg gatcaccggt taaattgaaa tagacatgat ttgtaggatt
    16201 gaatactgtt ttgcggtcac tgatcccttg gaccgtcact cgccatgtat catcgttcgt
    16261 cagcgtatac cgtacttcta catctaaagt tccaggaaat ccgttttcca tatctgggct
    16321 agtctgatag aaaatgaccg atgcttcgtt ttcaccattg atgactgtat aatgccactg
    16381 cttggcttca aagctaggtg caccaccatg taaacaatga ccagtgtccg ggtctgtttt
    16441 tacttcgaac gtttcatcat ctaatttgaa tgtgccattc gtaatccgtc cagccatacg
    16501 tccgattgaa gcaccgatat aagggtcttt ttctagatat tcttttgctt catcaaaacc
    16561 taagatcaac tctcgttttt cattatcgat tattgtttga aaatgaacaa cccgtgcccc
    16621 aagatcactg acagacaaag atgtcccatt ttgattcgtg atcgtaatca agtgatagtt
    16681 ttcgccaaaa ttttgttcat tgatttccat gttccttgca ccctcttttc tttcatttgc
    16741 actgattcca gtatacatgg aaaccgtttt cttaacagct tattccgtga gtaacgagaa
    16801 aaaatttact atattctaat aaaagaccgt gaaaaaaagg ttgtgacaaa aatattgtca
    16861 caacctcttt ttccgaacaa acggtgttca aaagcttgca tctgcggtaa taagcccaac
    16921 caaacgaaaa atatgaggag ctatttttgc ttggctgttc ttattacttg atgcaggaca
    16981 gctttttcac aatctctttt tcaatacgat tccagtatat aaccatgtcg tcagtacata
    17041 gtagatgaaa tacaatacga agaatatcgt aaacggaacc caaatatctt tgtatggatt
    17101 ttgcatgaat agaccaaaca tttgtaatcc gaataagaca tggactacac ctaagattcc
    17161 tggtgctaag aataacacgc ctacttctct acggatcgat tgtttaagca acccgcgtcg
    17221 tgttcctatc ttttcaagca tttcataacg agcaatgtca ctcttgcttc ctgacaagat
    17281 cttgaacatc aaacagctag caagcatggt caagaaagct aaacctagga agaatcccat
    17341 aaattcaaaa ccagagaata gaccattata cacttcatac atttcatatt tctggttgct
    17401 gtactctact ttttgcaaag atggattgtt cattttattt tgagcaacaa gtgtttcgat
    17461 tggtttcagg tttgcttgga agtcttttac ctgaactagc tgtaaagtgg attgtggcaa
    17521 gttcagttga tcaaattctg attgactgac taccttgatt tctttttctt gctgttccgg
    17581 caattcatag cttcgaagtt cctcttgtac agtcagttca ttcatttttt tagcaggaac
    17641 tttttctttc gtgatcttcg gcggtgttcc atcttcatgt tttatcatga tcaatggttg
    17701 agccgcaaat tcacttgcat tatagtaaat cgttcccgca tcttcttttt gagtataaga
    17761 agcagaaagt gttggtgaaa gttctttgat tttttgctga tcttctgccc gaggattatt
    17821 catcactaga tcatatccag aattgttttc tgtcaagtct gcaatttcat ttttaaaacc
    17881 taatcctacc gtcaaagcgc ccagtgccaa ggcaaacagc atagcgacca ttgagagcat
    17941 ttgtgtatat tcacgaatac gaaagtttaa ctgtgacaat gtgaaattgt tcaatttttt
    18001 caatgaaatc tgttctgatt tctttagtaa tgataaaaag aaaatgatca cagaatggaa
    18061 aatgaaataa gttcctaata cgatcgtaac taaggctacc cctataccaa agacttgata
    18121 ggtccccacg tgtttcatca tatagtaacc gcagcctaga aaagcaattc ccagtactac
    18181 ttcaaggaaa aacaagaatt tatgctgctt gattcttgtt ggtgtctgat ccgcacgaat
    18241 caatgctaaa atcggttttt tgacaatcga aaaagcattg acaacagcag ctaataaaaa
    18301 caaaacagca aaaaacaaaa cagtgatcaa caacccgtga atactaaaag gtgtaaaatg
    18361 cgaaatattg agatctaact gatccactaa taatcggtgg acgatacttg tcaatcctac
    18421 accgacagct gaacccacta aagtagctgc gatccctact aagaatgttt cagaaaaaat
    18481 catctgtgcg atttttctgc cttttgctcc cagcatcata aacattgcat agtctttttg
    18541 ccgcatcgtc atcaaaaagg aatttgcata taaaatataa acgaatgtga tgatccctag
    18601 taaaacagaa ccgaatcgga aaatgataac tgtagccgca acgatcgtat tacttttcaa
    18661 aaaagcttcg ttgcttgcca ttgattcaaa catgtaaaaa atagcagatg ccataactaa
    18721 tcctgagaat aacaccaagt agtctcttaa acggctcttg atcccagtaa gtgataattt
    18781 ccaaagcata gtcaatctcc ccctactgtt ccaagtttcc aagaatagat agtatttctc
    18841 gatagaagga atcacggctt tgatctccac gtttcacttc ttgatggata ccgccatcct
    18901 tgatgaataa aatacgttgg caataacttg cagaaaacgg atcatgcgtc acaagaagaa
    18961 tcgatacatg atcttttgta ttcaattcgt ccatcgtatc taaaagatcc cgggcacttt
    19021 tggaatccag cgcacctgta ggctcatccc ctaatagaat cgttggttgt gtgatcaatg
    19081 cacgtgcggc ggcgacccgt tgtttttgtc caccggaaat ctcagaagga tagctttcca
    19141 aaatatgaga gatggataaa cgttctgcaa ttttttggac acgttgcttg atttcttttg
    19201 gtctgacgcc ttgtaaagaa agaggaacag cgatattttc ttgtgctgtc aagctttcta
    19261 ataaattgaa atcttggaaa ataaagccaa tctcattcgc acgaaaatct gctagttgat
    19321 ttccttttaa tgtggtcaca tctttttgat tgattcggat atgcccatct gttggtttat
    19381 ctaatgtgga taaaatattc aaaagtgtcg acttaccaga accagaagcg cccatgatcc
    19441 caataaattc gcctttttct acatcgaagc tgatgccgct taatgcttgc gtctttttct
    19501 cattgttttt tccgtatact tttgttacat tctgtacttc gactattttg ttcatttctt
    19561 tccctaccct ttaattagtt tttccagtgc tgttttcggc acgtcttttt tttcgacttc
    19621 ttcatacgaa gtgacacctt tatttttgtt ccaggtgatt tttaaatatg ctcctttacg
    19681 aagcggtcga gtcaattgtc ccttgaagtc cagttctttt tccttaccct ctttcgtata
    19741 gccaggcagg atatatctat agttgactgt ttcttgtcca gagtctgatt ttgaaactgt
    19801 ttttgtacca tctgtcgtaa tttgtacata gtattcttct ccacccataa ctacgtaatc
    19861 tgcgattttc acccctgcaa gtaccacaac gatgaaaaca agtagaccga tcagaagttt
    19921 tttcactttt tccccttctc tcttacttta tatactgatt atagaaaaaa gcgaacaatt
    19981 ctgccttcga atcaactatc attcttcttt caattttgtc attttcttta aaacaactaa
    20041 aaaaagagtt caagacaata atccgtccta aactccttct tcctatctta caaaaagtat
    20101 gtcacttacg gtctttcatg tcgcctgtat tgataacagg ttgcgttcct ttgtctgtaa
    20161 tgattgagac aagtaaatta ttgatcaatt ggactttccg atcatcggtg aaattgattt
    20221 cttgtccatc ttcgatttgc tctaaggcca tttgagtgat tgtgacagct ccttcaacaa
    20281 tggtttgtcg agcagacaaa atggcttttg cttgttgacg ttggagcatg gcactagcga
    20341 tttctgttgc ataggctaaa tggttcaagc gtgtttcgat tacttcgaca cctgctactg
    20401 ctaaacgctc ttgcagctct ttttgcaact cgtcagacac tgccgtcgtg tttcctcgaa
    20461 gcgtcaaatc attctcattg aatgtatcat acgggtattg gctagcgata tgccgaatgg
    20521 ctgtctcact ttggatttct acaaaatctt gataatacgc tacatcgaat aatgcctttg
    20581 ctgtatcaac gactttaaag actactactg ctgagatttc gatggggttt ccatccaaat
    20641 cattgacttt taaaacagaa ctattgaaat tccgaacttt caacgaaaca gtcatttttt
    20701 gtgccaaagg tatcgtaagg aaaaagccat tttctcgaat cgtacctaaa tattgtccaa
    20761 aaaacaaaat tacttttgct tgattaggac tgactacagt tgccgaactt aacaacaata
    20821 acgtgatcaa ccaaagaaaa atacttaaaa aaagtgccca aactttcgct tgccacatac
    20881 ctaaatagaa gaaaaacaat ccaactaaag ctaatacgac caatccgaca atccctgcat
    20941 aaccattgat ataaaatgct cttttttctc tcatgctact tcctgcgctc ctttatcctt
    21001 caataaatat ctaatgttac ttttttaatt tttttttcga atacgcgcca ttacaccttc
    21061 tagttctaac tctttgtctt cagtgatgta ccaaccgctt gcctgtgtcc ctccggctgc
    21121 ctgcggtaaa taatccaatt ttgttcgaac ccagtgcttt tcttctgtaa aatagtcttc
    21181 taccaagacc tctagatcca tccctgctga aagaggcaaa tcttcccgaa cagatttaaa
    21241 gataaatcgt tccttcttcc catcatactt caatattcct gtatcgataa tcggtaaaga
    21301 ataataatcc agctctttct tcaccgtcaa taaatgtttg aaaacttcat ggtacacttg
    21361 ctctaattgg cgaccttctg aattgttcgg gtaattaacc atcacttttt ctttgtctgg
    21421 atcatagaag gtttggctta gttgagtgat ataagtatgt aatctttcca tttctgtttt
    21481 taacttttct ctttgacctt cttctacctt catatactct ttcaccctgt tttcttttta
    21541 gatattttct ttcttatttt actatagtta tgtgcgttaa gcgatgaaaa acagcaaaga
    21601 ttggaaggat ctttgctgtt ttttcttaaa atatccagtt gagtacagga tcaatctgtt
    21661 tcattgtcct cttgatccgt cgtaatattg atcgatgtgt ctttagcagt gatctttagc
    21721 tttttctgtc cttgttctaa caaagtattt gttattggct ggtagtcttt ttcaatataa
    21781 gattcaccag acgtttggat agtatagcca ctgttttcca tctcatgcaa agataaattg
    21841 ccaccgttta ggatgacttt tccttctttg ctgatcaaac tgtcttctag atggaagttg
    21901 ctgttttcac ctgtgacgat caagttatcc acattggcct catctaatcg aagtgagcct
    21961 aattcatctt tcgcagttat tgttcctcct gtaaattcat tgaacgatac ccagccatca
    22021 tgtgtcttag tattcacttt tttgattgat acttcgttga tatcaattgc actattattc
    22081 ccttcgattg tcaattcaga taattcatga tctgcaggga caacaatagt gatttgtgca
    22141 cttgtgtctt ctaaactaat gattgcacct gttgattttt tgactgcatt cacagtcaac
    22201 acgccatttt tctcctttat ttctggcttt tctgtcttat cataagtcgt ttttatctca
    22261 aaatccaatc cgcgtatgac cgaaactgtt tgattttctg catggatgac gattttgttt
    22321 gcatccttga ttttttttgt ctcagtaacc atatcgatca accgaggacc attatcccaa
    22381 gtcagactct tttgagcgcc taatgtataa gttgcacctg ctaggaggcc accagtaagc
    22441 atcagaccaa taccggtaat caaaaaatgt ttcaatctca atttatgtgt cctccttcaa
    22501 acgcccgctg aatgcagatc tctttttgta ataaaacgtc gtcccatcca tttaacaaag
    22561 ttcatcatga cataaaaaag cccttttgtt cctttcagca acagtggcga aataaatact
    22621 gcgcttcctg tggcgaacag accgacaccg ataaagaata atccactcag aatcgattgt
    22681 ccaaacacac tgattcctga gatgatcatg aataggccaa cacctaagat actgatacat
    22741 aaaacataga tactaaaaat gagcgctagt aaagcaacca atagtccccc aataaccaat
    22801 ataaacccca gtgctagtgg aatgaggaca ggagaagcaa ataaaccgat aatgattaac
    22861 caaatcaggc gaatttgtct ttttggattt ttcactaact cgttttctgc ttgttcttct
    22921 tctgaaaagt aactgatttt taattttaag gcaaactgct ttggtgtacc atattcatca
    22981 atgatctgat ctaatgtttt tccagaatct aaaaaatatt cctcataata ctggatcaaa
    23041 tcaaaacgat cgtcttcagg aatttcttga agatgatcca caacttcatt caaatattca
    23101 ttcatttgtg ctctcctcca ataaccggtc taaagaatct cgaaaaacaa tccattcatc
    23161 aataatttct tctaaatgac gacttcccat tggtgtcaac gagtaatatc gacggtttct
    23221 gccttcaaaa ggttcatcat aggtctcaag atatccttct tttttcaatc ttctcaaaac
    23281 cggatatagt gtagattcac tgacagagag actttcttgt acgatttttg ttaaggcata
    23341 cccatacata tcttccttgc ttaatgctgc tagcacagta ccatcaagaa gaacagttgg
    23401 aatctggatg tgcattacgt caccttctat tctcaagtgt aatattttat ttcaatctat
    23461 attatacaac atataatata gtttcaaaat cagtttgtca aatacaaaaa aactgactaa
    23521 aagatttgat cctttttagt cagcaaaaaa tggcttctct ttgattttta ttataacagt
    23581 ggcataatcc aatttgtcca catccagctc agtggcatga taacgatcat tgcaggtatc
    23641 atgtcagcta ctgggaacat tttcacgttg atcattctaa aaccggtagc gaccatcaag
    23701 aatccgccgc aagctttaaa atctaagatc atgtctggtg tagtcaatgg ataaataaat
    23761 tttgccaata agaacaaaat ataaaaaata atgaattggg gaattgctat cacagaaacg
    23821 acatacccta aattacacgc aaaaatagct gctgtgaaaa aatcaaggac agatttagaa
    23881 atcaaaatcg tactgtctcc tgtcatccca gaatctaaac ttccatagat ccccgtacca
    23941 cttgcacaaa atagaacaat gaccgtcact aatgtgctga taaattcatc gtgggtcata
    24001 ccaagctttt cactagggaa gattttagaa ataggtactt gcatcagcgc agccccctta
    24061 tttatcccat tacctaaatg aacaatcaaa ccaatcgctg ttcctatcac taaagcaaaa
    24121 ataacagccg gcatattttt catcggcgca atggaataga ttcccatccc catcgaacac
    24181 acaccaaaaa ccatcgtcag ctgtgcttta aaatgttcac ttaatttatt tcctactaat
    24241 ccgccaatta gtccgccaaa caaaacggaa cctacattga tcaaaactcc agttggcatc
    24301 aaaaaactcc tctctttttc tacgaagcga aaaaaatcag aaaaatttct gtaattattg
    24361 ctttcgctgc aagaaagatt gtaacagaca gagaagatta caccaattca ttttttgtgt
    24421 taaagtattc tttattggaa taagtaggag gaatatgatg gatatccata aattcgaagt
    24481 ttttcttgat ttagccgaaa caatgaattt caccaaaact gctgatcgac aattcaccac
    24541 ccaaggaaat atttctaaac agattctttc gttagaaaca gaattagacg tcaaattatt
    24601 cgaacgcgcc catagaaaaa tcgaattgac cgaagctgga agcttattgc tcccatatgt
    24661 aaaaaatgtc gtagaacaat accatgctat gcaagaagtg cttgaaacct atacgaaaga
    24721 caacaatctt tcattaaata tcttaacgat accgacaatg atcaattata aaggtttttc
    24781 caaaatcacc gagtttttga aacgccatcc tgaatttaca gtccagttga aagaagtgga
    24841 aagtgtcgaa ttaacttaca atgacgccaa tgaacatagt gacacgatcc actttgctag
    24901 aagtttccag gccccaccaa gttcgattga gtggttgcct actgaaacag acgattttgt
    24961 agcagttcta cctaaaaatc atcctttagc tagtaaaaag aaattggatc taagcgaact
    25021 gaaaaaggag aactttttgc tccttggccc cactacgaac ttgtatcaac ctgtactaga
    25081 tctgtgtcgc gaagctggat ttgaaccaaa aatctcttat aaaggagcaa gaatcgactt
    25141 gatcatcaat atgattgcaa atgacatggg gattgctatt gttatggaaa aaacagtcaa
    25201 gaatctatta aaagaaaata ctgtgattct ccctatttct ccaacaacag agagttatct
    25261 tgcatttact cgtaaagtcg gtgagcattc tttggcttca gatacatttt gggagtattt
    25321 aaatcaagaa gaaaactaag ccctacattt tctgtccatc tatccaccca aaaaaagaga
    25381 gcgacgcatg actttcgctc tctttcttgc atcatgtcct tgtttcaatg acacctctaa
    25441 catttctcgt agttcaataa gaaagcagcg atttttatgc caaaagaacc gtaagaacat
    25501 ttccctaatc acaaaaaaac gactaaaaac ccctaaaaac cttcaataga atttttaggg
    25561 gttttattct ttttcctatt gtttacttaa ccgtatcatt gctgtcgttc ctactccttc
    25621 gatactgcta taatcaatac gtccatcatg cagttctaga atttttttaa ccagtgaaag
    25681 tcctagccca ttcccagaaa tttgacgact tgtatctcct tgataaaatt tttcaaacat
    25741 tcgatctctg gtctcttcat tcattcctac acctgaatcg gtcacttcca gtacaatctc
    25801 tgtggctgtc tcaaatagtt tgatatgaat ctgtccattg atttgattgt actttatggc
    25861 gttatccatg atattcagcc acacttggta caaaaactct tcattgcctg tgtaatttac
    25921 tgcagcaagt tcgatatcca attctagctg ttctttctcc catttaggct gaaaaaaaac
    25981 gattacttct ctgatttgtt catctaatcg atactctttc ttttccagtt ggatacgctg
    26041 gttttccagt ttgttcaatt ttaagatgtt ctctgttaat tgtgaaagct gcgtgatact
    26101 ttcgataatc cgatataaaa atatttggcg ttcttcgtca gagagatttg gggcttgtaa
    26161 caattgaaca tatccttgga ttgttgctag tggtgttttg aattcatggg atacactgga
    26221 cacaaagtca ttcctcagtg tctcgatact attgagttct tggaccataa cgttgaaatc
    26281 tttatacagt tgctgtactt ctgctacttt ctgctgttca tccattcgaa tcgaaaaatc
    26341 tcccgttgct accagactca tatttgtccc tagcgcactg attggatgca ggatacgccg
    26401 cccaacaaaa atcgatattc ctgtacccac gaccatactg aaccccgcaa agacgaataa
    26461 cgggtataac gttggttttc cagccgattc agcaggcgag atagaatgtc gagacaataa
    26521 gaaaataaaa ccgagaaaac acagcagtgt cactaagatc gaaatgaaga caatactagc
    26581 aaaatagatc cataattgtg aaaatagctt ttttttcatc tttaaataac cgccttatag
    26641 cctagtcccc gtactgtgat gatttgaaaa tcttccgtct tttcaaaacg ggtccttaaa
    26701 cgtttgatat gtacatcgat cgttcgttct tctgtattcg tatctaatcc ccaaatatca
    26761 tccatcaact gttggcgagt gaagatcttg ttgggataag acagtaattt atacagaagc
    26821 agaaattctt tttgaggcag aatcaacgaa tgctgatctt gtaacactgt ataagcatct
    26881 agctctaatt ttgtttgtcc gattatcaag ctactgctgt aattgatctt tgaacgtcga
    26941 agcaatgctt ccacacgtag gatcatctca ttgacatcga tgggttttgt catataatca
    27001 tctgctccta atttgaaccc gcgtttctta tcctcaaaat cggcctttgc cgtaatcatt
    27061 agaacaggtg tgtcaaatct ggtgctacgt aatgagtcta gcaagtcata gccatccatt
    27121 ttcggcatca tgatatctgt aatgattaat tctatacgtg tcgcttctag ttttttcagc
    27181 gcatcctctc cattcaatgc ggtgatgact gaaaagcccg ctcgttccaa cacagaacgg
    27241 taaagcaact gtaattgcgg atcatcttct actactaaaa tacgattcat tgatctccct
    27301 ctgttttttg aaaaatttct agattttttc ttgtagttca tcttcagtta acatttattt
    27361 cgtatactac gatcattgtt ctgatatact tattagtata ccgaatattt caatacggga
    27421 gaagggtgat tatgcttcaa ttaaaagata taaaaaaata ttataaagtc ggcgaaacca
    27481 ccaccaaagc attggatggt gtgtctgtcg ctttcagaca aaaagaattc gtagcgattt
    27541 taggtcctag tggttctggt aaaacgacta tgctgaatgt gattggtgga ctagataatt
    27601 atgattccgg tgatatggta atcaacggaa agtctactaa agactttaag gacagtgact
    27661 gggatgccta ccgaaacaac tctatcggtt tcatttttca aagttacaac ttgattggtc
    27721 atctaggcat tattgaaaac gttgaacttg ggatgacatt aagtggtgtt tctaaagacg
    27781 aaaaacgaaa acgggcagaa gatgcattgc accgagtcgg cttgacaaat catatgcata
    27841 aaaagccaaa tcagttatct ggtggacaaa tgcagcgagt ggccatcgct cgagcactag
    27901 ccaatgaccc agatatcctt ttgtgcgatg aaccaaccgg agcgttagat acagaaacaa
    27961 gtatccagat catggaattg atccaagagt tatcgaaaga aaaattagtg atcatggtca
    28021 cacataatcc tgaactggcc catcaatacg cagatcgaat cattgaattt tctgatggta
    28081 agatcttaac agattcccat cctcacatcg aacgaccaaa agatgatcaa tttaacttac
    28141 gcagaacaaa gatgagtttt tggacagcgt taaagctttc cttcaacaat atccgaacaa
    28201 aaaaaggacg tactttcttg acctcctttg cttccagtat tgggatcatc ggaatcgcga
    28261 tcgttctgtc cctttcttct ggattccaaa aacaaatcga taacacgcaa gctgaaacga
    28321 tggcgaaatt tccgattact atttctaagg taacgactaa ccagactcgt gacgatgccg
    28381 gattgggtgc aagcaaagcg gattatccag acagcaaaac gattactgca aaagtcagcg
    28441 aagaagataa agcacagcac acgaataaga ttgatcaaac atacgtcgat tacgtaacag
    28501 acatcgatcc taacttaagt aataatatcg gatttacccg tactacagga atcaatcttt
    28561 tacgtgatgt aaatggcaaa gtacagcctg tcagcttctc gaatcaaaat cctgatacgg
    28621 aatctctttc tttatctagt acgatgtcag caatgacagg tgtgggagtg tcaagtttcc
    28681 ctacacagct tgacactagc aaagaaaact ttttaaaaga caattattct ttacttgccg
    28741 gaagttatcc agcctcagca acagatgtcg tgctgatcgt agacggcaat aataatacta
    28801 atatcaacgc attgaagaat cttggatttg atgtgaaaga agacgaaaaa cttgattttg
    28861 atgatatcgt tggtacaaca ttcaaattag taaacaacaa tacttactat acaaaacttc
    28921 caactgggaa ttttatccct aatacagatt atgatgcgat gtatcagaat gcttctgatg
    28981 aattgaagat ctcggggatc ctacgcgtga aatcttcttc tacaatgaat ctcttatctc
    29041 caggaatcgc ttatagcgat caattaacga ctcaaatcgt caacgaaaac aaagaatcag
    29101 aaatcgtcaa agctcaaaga gacagtggtg taaatgtctt aactactgaa aaagttgacg
    29161 aaaatgccaa acaaacattg cttagttatt taggtggaga cagcttgcct tcaagtatca
    29221 tgatttatcc gaacaatttt gaagacaaag aaaagatctt ggattatcta gatgattaca
    29281 ataaaggcaa atcagatgaa gataaaatca tttatactga tttagctgga acgatgactg
    29341 aactgactgg cggattgatg gatgctatca cttatgtcct tattgctttt gcagggatct
    29401 ctttagtaac aagtatgatc atgatcagta tcattactta tacatctgtg attgaacgga
    29461 caaaagaaat cggtgtacta aaagctttag gtgcacgtaa aaaagacatc actcgcgtat
    29521 ttgacgcaga aacgtgtatt ttaggtattt cttctgggat attaggtgtg tttattgcat
    29581 ggctagctac gttccctatc aatagcatct tatacaacat gacggatcta aaaaatgttg
    29641 ctcaactaaa tcctgtccat gcgattattc tagtgatcgt ctctactata ttgacgatgc
    29701 ttggcggtca tcttcctgca cgaatggcag cgaaaaaaga cgccgctatc gctttgcgtg
    29761 cagaataagg ttgtgacaac cacatttaga tttgagtcat aagagcgctg aaatagtaga
    29821 aaacagcaag aaacgaggaa gtaatatgtt ccttgtttcg cgctgttttt tttaattatt
    29881 ttttataatt ctggtatact tttctttcct ttgtaccaca actcttctgg cgtatacctg
    29941 tcttttccat ttatgaatac tgttccatct gcttcaatcg ttacttcagt cccaatccac
    30001 atattacgag aaagtgcgag aagatttttt ctttttcctc ttcctttttt tccaaattgc
    30061 aaggcatcgg ttatctcttc tgtccaatga gatttcacgt attttacttc tccgttttca
    30121 aatgtaactt tcaaaatatt cgctatattt tccactttta ctgctttagg aaatgactcc
    30181 tccatttttt tcactttcct tcctccaaca ctaagtatgc gctttctttt agtgataagt
    30241 atatcatagt ttattctatt atcaaaaaaa cgcatccatt ccattgtaga atactttacc
    30301 gaacaagttg aattgttttc ctctttttca ccttttacta tagataggta aagacaacta
    30361 aggaggaatc tctcatgaca gatcaaccgt atgatttaag aaaagtcatc gaagaactaa
    30421 aaacacttcc aggtcaatat cacgaaacag atattgaaat cgatcctgaa gcagaattat
    30481 ctggtgttta ccgttatatc ggtgctggcg gtacagtaaa acgtccgact caagaaggac
    30541 cagctatgac tttcaacaat atcaaaggtt tccccggcac acgtgtgaac atcggaacaa
    30601 tggctagtcg taaacgtgta ggtgaaattt tgcaccatga ttatcgaaca cttggtcgtt
    30661 tcttgaaaga cgctgtagaa aatccaatca aacctgtgaa agtagacaaa gcagacgctc
    30721 cagcacaaga agtcgttcat ctagctaccg atgcagactt cgatattcgc aacattttgc
    30781 ctgcacctac aaatactcct gaagatgctg gtccatacat cacaatgggt gtagtcttag
    30841 gatcagatcc agaaaaaaca atgagcgatg taacgatcca tcgtatggtt ctagaagata
    30901 aagatacgat cggtatgtac atcatgcctg gcggacgcca cattggtcac ttccaaaaac
    30961 aattcgaagc cttgaataaa ccaatgccta tcactatcaa tattggttta gatccagcaa
    31021 ttgccattgg cacgactttc gaaccaccta ccactccact tggctacaat gaactatggt
    31081 gtgcaggagc tttgcgtaac gaacctattc aaatcgttga tggtatagca gtcgatgaag
    31141 tgggtattgc tcgtgctgaa ttcatcattg aagcagaaat catgccaaat gaaacaatgc
    31201 aagaagatat caacacgaac tcaggaaaag caatgccaga atttcctggc tatactgggg
    31261 atgctaatcc agctgtacaa gtagtgaaag tcaaagcagt tactcaccga aaagacaatc
    31321 caatcatgca aacaacgatt ggtcccagtg aagaacacgt atctatggcc ggtattccta
    31381 cagaagcaag tattcttgcc ttggtcgata aagctattcc aggaaaagta gtaaatgtct
    31441 acaatcctcc tgcaggtggt ggtaaattga tgaccatcat gcaaatccgt aaagaaaacg
    31501 aagcggatga aggtattcag cgtcaagcag ctattcttgc tttatcagcc ttcaaagaat
    31561 tgaagacagt cattttagtc gatgaagatg ttgatatttt cgacatgaac gatgtagttt
    31621 ggactttcaa cactcgtttc caaggagata aagatatcat cgtgatccca ggaatgagga
    31681 accatccatt ggacccatca gaattaccag aatataatcc tggctctatt cgtttccgtg
    31741 ggataagtgc aaaaactatc tttgacggta cagttccttt cgatatgaaa gaacattttg
    31801 tacgtgcaaa attccaagaa gtagaagatt gggaaaaata tttgaaataa tgaatgatct
    31861 gcaactgttt tgacatcata aaaaggagtg cggaaaatgg aacaattggc acaacggaag
    31921 aaaaaaatcg tgattggtgt aagtggcgct tcaggcacca tttatgccat caacctagtg
    31981 aagaaactaa aagaatatcc gatgatagaa acacacggaa tcatcagtcc atgggcaaaa
    32041 cagaacttaa agctggaatc cgacttatca ctaactgaat tcgaaagcct gtttgattac
    32101 cattattcaa acaaagattt aggtgctgct gtcgccagcg gatcattttt gaccgatgga
    32161 atgatcatcg taccggcaag tatgaaaaca gtcgcaggta tctctgttgg tttaggcgac
    32221 aacctgattg cacgtgctgc tgatgtaaca atgaaggagc aacgaaagtt agtcattgtt
    32281 cctcgtgaaa cgccattaaa tgccattcac ttggaaaact tgactaaatt agcacgacta
    32341 ggtgtgcaaa tcataccacc aattcctgct ttttataatc agcctcaaac gatccaagat
    32401 cttgttaatc accatacaat gaaacttttg gatcaatttg aaattgtaaa tgagcattca
    32461 aaacgttggc agggtgatta atatggaaaa agaaacgata gttgaagtaa ccaaactagg
    32521 tttcacgatc caagctgctg ttaaagtaat cggtaaagac ttattgatca ctttaacagg
    32581 cggagataca ccacatatcg gaacagtcac tacattttct cgtgatacag agatgcaaac
    32641 tgtacgtttc cctagccacg atggtcggtt ccataaagac gatgtcttag ccgaaaaaat
    32701 agctgtgatc atcaaaactg ccgttccggg aagttgtacg atcacttccg gtatccatgt
    32761 tgaccatatc tccaatgcac aaatcaacgc ctcttttccg atgtcagaag agttaggtta
    32821 caagatttta gattggttgg aaaaaataga tttccatatc aaataaccag tttattataa
    32881 agatggtgaa aaaccattat gaaagaagag gttgtgaaat cagcgttatg acctgagtat
    32941 gagagaaaaa aatggaaaaa tagcttctca tattttgccg tttttgagct aataccgagg
    33001 gacagctgat tgaacgccgt ttatcaagag gttgtgataa agccgcttcg tttcgagtag
    33061 taagaaaaat tttgtaaaca tgggtttcca catttttgca taaatttgac ttactaccga
    33121 gaaactggct tttgaacacc gtttatcaag aggttgtgac acgtcttttg tcacaacctc
    33181 ttttattttt gcttcactgt aactgctaca atatcaccga tttcttttcc gatgttttta
    33241 cgaatatctt ttcgtagtcc aaggatgtag cagactgaac catctggatt tttcacgccc
    33301 atattcacga tactgccttc atacggcaca ttgtcaaaag ttgcttggac tttaactctt
    33361 ccagcaccga attcttttct tatatcatac ggaaaaataa tatatgcccc gcccttgccg
    33421 acttcggaag catagatttt tgattcaaaa gaataaattt ccctcatttt atttctccta
    33481 ttttttacat ctagtatagc atagcaaaaa aaagaaggaa ctgtgacaaa agtcttgtcg
    33541 cagttccttt tttcgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat
    33601 agtcaacaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttaaacgg
    33661 caggctcaca acctcttcct taaacggtgt tcaaaagctt gcatctacgg cactaagccc
    33721 aatcagatga aaaatatgga gtgctatttt tatctgattg ttcttactgc ttgatgcaga
    33781 gcagcttttt cacaacctcc tacatggtgt tcaaaatatt attcgccttt tgcttctttc
    33841 actaattttg cgaatgcttg ttgttggaat tcagcagcta aggctttcgt acgttgttct
    33901 tgctctgctt tgctcatttt tggattttca gtcattgctt ttaccatacc gtcttgaaca
    33961 taagcttttg cttcactttc catcgtactt tgctgtttct tcactaattc agctaacttg
    34021 gctgcttggt ccgtacttaa ttctacccat gtctctggga ttttgaatgt attcactcgg
    34081 ctgtcatatt cgtgattgtt atcagcaata ttgaaccaga atttatacat gtcgtttttg
    34141 tattcccaat aagtagtttt cgtcactttt tcagcatcgc cgtctgtctt ttctacttta
    34201 tttgtttcgt tatccgtacc agttgctttt ggtttttctt gtttttcatt tgttcggtaa
    34261 agatacactt tttcttttcc attccctaaa gctttataca aaagcatatc tgctccttgg
    34321 gaatcagcac tggaaacaat tttttctgtt tttgtttccg ttactttttc cattccaaag
    34381 tgattggaca aattagcgac gatcaaactt agtgaagcga cgaagattag tccgaaaatc
    34441 aaagataaaa aggtttgcca tgttttttta gcgaacacgt tcgttaaagc aaaagcaagc
    34501 aagctgacaa tcaaaactcc aataatcatg cattatcccc cgctttcatt agaacaggtt
    34561 cttttttctt caataaaaag gcaataataa agccaagaat cccaaagatg atcgctacga
    34621 taaacgcggc atggtaacct gacagtgtgg cattgattgc ctgatcttta taagctaatg
    34681 gcgtattatc caatacagat ttgcttggga tatttgcttt tgtcacattc gtcaacacac
    34741 tgatcaaaat agctgtacca atcgagcttg cgatttgacg gaatgtatta tttaccgctg
    34801 tcccatgact gatcaagtta tttggcaatg cattcatacc agaagtcgtt accggcatca
    34861 tgaccatgga gatcccaaac atacggatcg cataaaggat cacgatatat aaaactggag
    34921 tcgtttttgt caagaaagca aatggtgcag ttgccgctgt caaaatgaac atccctgtga
    34981 tggctaaacg tttcgcgccg tatttatcga aaatcgcacc cgtcacaggc atcatagccc
    35041 ccatgatcaa tgcacccggc aacaacatca agccagaatg gaatgctgat tctccacgaa
    35101 tattttgaat atacaatggt acgaccattt ctgcccctac catcgccata tttgttacac
    35161 cagctaaaac agctgcaatc gtgaatgtag atgatttgaa tacacgaagt tccaagaatg
    35221 gatgttccaa atgtaattga cgccatgaga acaaggcgat gaaaatcaca ccaacaacta
    35281 agaaaccaat tactttcaag cttccccagc cgtcatctcc tacactagaa aatccgtaaa
    35341 gtaaactacc gaatccaatc gttgataaaa tagcggataa aatatcaatg ctaggatttg
    35401 acaatggaat aacacttttc attaggaaga atgctaaaac caagacaaga acaacgattg
    35461 gcagtaccat accaaacaag tcacgccaat ggtagttatc aatgatataa ccagataatg
    35521 tagggcctaa agcaggagca agtccaataa cgatccctga catccccatt gctgatcctc
    35581 ttttttctgg cgggaaaata gatagcatga tattttgcaa taatggcatc gatactccca
    35641 caccgcaagc ttggatcaaa cgaccgatta gtaatgtact aaaattaggt gctgtaaagc
    35701 aagtaatcgt tccgatcaaa aagatcgtca tggcagaaag atataaattt cttgaactga
    35761 atttattgat cagccatgct gttattggga tcatgatccc gttgactagc aagaaaccag
    35821 tcgttaacca ttgcacatca gacgctgaaa tatcgaaagc tttcatcaat gtaggaaaag
    35881 ctgtcgtcaa taaggtctga ttcaaaacgg tacaaaatgt accaattaat aagacaacaa
    35941 ctaaaagtgt ccgattatat ggttttccgt aaatatctac gggttggttg ttactcatat
    36001 ttctccttct ttctgaattt tttctgaaac tactagaata ctttagtcct aaattcgcta
    36061 tttgtcaacc tacttgacac ataagttaat acggatataa ttaagggaag caagaggaca
    36121 aaaggagtga caaaaatggt tggggcttcc cttaaacgtt tgttggaaaa tgatcaattg
    36181 gttgttggca tcagtgaatt aagtgatatc gtaggtgtgt ctccacgtca attaaggtat
    36241 tgggaacaaa agggattcat tcgttcgatc gaagctgatg cgaattgtcc tagaaaatat
    36301 cgtttaccta cagtcataaa agtagaactg atcaaaaaat atttagatga cggatttact
    36361 ttgtcaaaag ctgcagaaaa ggcagaaatc cgccaaaaga aaatgcacca tgtccgtaaa
    36421 gttttttcaa aagcaatcaa agatatcgaa ttgatcgacg aacgctatac gattttacaa
    36481 atcggtaact tcaaagaaga gaatgctaag atgtacatca ttcatgacaa cgagacagac
    36541 gaattaactt acaagctcct tcctgtcgat gaaaaagctg actacgaaca gttgttaaaa
    36601 gaactctaaa cgccactaat ctcctaagta ccaagctttt taataagtag atgctacata
    36661 aatacttgaa aaaaggcctg tttgaacata agaatatccg aacggtgatc tgcgtttctt
    36721 tcatatagaa aggaattctc catcactgtt cggatatttt tttatttttt tcggttactt
    36781 tcttctaata catctgttag ccaatttgca tattctgttt cccgattgat cgcatgcgct
    36841 aaaatcaggt agtgtccgta attttcatgt ttttcttttt cagtaggaaa gatcgttttt
    36901 tttcgctcta atagatgaag tcgtttttct tcatgaaggt cacgctgctg ctgaataatt
    36961 tctactaatg ccggatcatt cacgtctttg acgaaataca atttcagaac aaattcgtct
    37021 cgattaaccg gtagttcatt ggtgggtgta tgaatccact ctgccaattg ttccttccct
    37081 tcttctgtta attcataaac tttcttttcc aatttttcac ctgtgatctc tacttgatgc
    37141 tgaatgattc cttgctcttc catttttgca agttcaggat aaatctgact atgttttgct
    37201 tgccaaaatt ctcctatttc atttttgaac gattgattca attcatatcc tgtcatcttc
    37261 ttcttactta ataaccctaa caaaatatat cgaagtgtat tttttcttgc catcagtttt
    37321 ccctccttga caaatcttta aatccattct atcataaatg agtaatcgaa aacatgtagt
    37381 ttattacatg ttttaattta taaggagatg cttaaacatg aaagaattta aagaattgga
    37441 agattttatt ggaactcact ttatctatac gtatgacaat ggttgggaat atgaatggta
    37501 tgccaaaaat gaccatactg ttgattaccg tatccatggc ggaatggtca aaggccgttg
    37561 ggtaaaagac caagaagctg atatcgttaa attgacggac ggcgtattca aaatcacttg
    37621 gacagagcca acagggacag acgtggcatt ggactttatg ccaaatgaaa agaaacttca
    37681 cggaatgatc tttttcccta aatgggttga agaacatcca gaaatcactg ttactttcca
    37741 aaacgaacat atcgcagaaa tggaagcagc tcgtgaaaaa tatgaaactt atccaaaatt
    37801 acttgttcct gaatttgcta cgatcactta tatgggtgat gcaggtatag acaatgaaga
    37861 tgttattagc gaagaaccat acgatggaat gccagatgat atccgtagcg gaaaatactt
    37921 cgatgaaaat tataaacgag taaaataagg ttgtgaaaga gaggttgtga aatcagcgtt
    37981 ctgacctgag tattagagaa agaaacggaa aaatagttcc tcatgttttg ccgttttttg
    38041 agctaatacc gagggtcagc tgattgaaca ccgtttatca agaggttgtg aaatcagcgt
    38101 tatgctttga gtaataagaa cgctagttag aaaatagctt ttcatatttt ctaggctagt
    38161 gggcttatta ccgagaagca gccgtttgaa caccgtttat caagaggttg tgaaatcagc
    38221 gttttgacct gagtattaga gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt
    38281 ttgagctaat accgagggtc agctgattga acaccgttta tcaaagattg taacaactgc
    38341 atattcacac agttaaatta gtgacttcaa aatgaaataa tgctcccagc aaaaaattag
    38401 gctgggagca ttatttcgtt attctgttca tcaaaaatca gcgttttgat tccatttcat
    38461 cacaagttcc tcctcattta ctgcttcatc tttttgctgt gtttgaattg taaaaccttg
    38521 tgaaagatag aaatgaatag ctgattgatt tttttgatag actgtcaaag tcagtgtttt
    38581 attggtttct tttatttttt tcattagttg cgtaccgatt ctttgttgcc ggtattccct
    38641 tttcacaaag attcctgcga taaactgatc aatcacccca gcaaaaccaa taatttcttg
    38701 atctatttct gctaagtaaa tcactgcatc tggtaaagct ttcctaacag attctacttg
    38761 attctcccaa taagttgatg gaatgaattc atgagaatcc aagttagcat gcagccaaat
    38821 cgatagaaca gattccagtt ctttggcaga caattttgtt gttgtgcgga tcattttttc
    38881 tctccttact tattcattga ttttaaaata aaaaccattt ttttgaagct cttttacaag
    38941 ttttcgcccc tcaaaaaagt atatcttctc ttgttttact tttctaatac caaaagaaac
    39001 agcaacttta ggatcatcag ctgaaacgat tcgataagtt ccaccaggca attgatccag
    39061 cttgactttc ccatgatggt cgctttgtac tgaaaacggc acaccatttc tagtaagtgt
    39121 ttttttctta tgtttcaaaa tgaatgaact accatttacc ggtttccctg acgaatcact
    39181 aataataaat gaaaaatcaa gcactttttt acttaatcta tactgataga ttagtcgtcc
    39241 gataaacact aacagtatga ctacagctat tatcgttcct gcaagaataa accattgccg
    39301 catggttctt tcctgatttc cttttccttc ttcttttttt accgattcgt tataaggaat
    39361 ccgatgtcct gtcactagca aacgatgcgt gttgatcata tacggcgtac atgtaagcaa
    39421 ggtaactaag tcttctcctt ctgaaatcgt tagaacagac gtgtcatctg gcagtaccac
    39481 ttgtatattt ttaacttgat aagccaattt ctcccccaaa acagtcaaaa taaacgtgtc
    39541 tccgttttct aaacgatcta attcggtaaa taaccgtcga ttaggtaaac cgctgtgagc
    39601 agagatcact gaatgcgtcg aatttccacc aagcgggaaa gaggttcctt gcaagacgcc
    39661 tgctccattt tcaaggatcc taccattgag ccgatcataa agtgaaatat ttaattggat
    39721 cttaggtata ttgatacttc cgatcagcca ttcctctaat tggctggatg ttgtactttc
    39781 atttctgttc ttttcattga aaggatcagt accaggattg aatccttggt cagttaatcg
    39841 ttggtttttc tcctccattt tctttcgctg cacttcaatt tcagctgcgg tccgtttttg
    39901 tacttgttcg atacgttttt gatcaataaa actatttaaa gaatccacat aaaatggata
    39961 taaagcgatc agtaacccta cgacgataca tattaataaa aacaaacgaa acaaaagtcg
    40021 acgagactgt ttttgcttac tctgcttcac atgtgtcctc ccttgcaagt ttttttgttc
    40081 tttcttttat tatatgggtt caggaaaaaa atagaaaatg aaagccgatg aggttgtgaa
    40141 aaagctgtcc tgcatcaagt aataagtaca gcccaaaaaa atagctactc atattttttg
    40201 ttgggttggg cttattaccg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt
    40261 gaaaactgcg ttatgctttg agtaataaga gcgctagtca gaaaatagct tctcatattt
    40321 tctaggctag tgagcttatt accgagaagc agctgattga acaccgttta ccgagaggtc
    40381 atgaaaaagc tactttgttt cgagtattaa gaaaaattct gtttcaaaac aaggagatgc
    40441 aacaaaactt atgtcgcatc ctctctcctt agaactttca cttatgtttt tcttgtaaaa
    40501 ttcataaata ttttcatgaa ttttctaatt tcttgcctac ctctcgcata ggatatatga
    40561 tgaatttatc taaagtttgc aaaggagttc gacaattgaa aaaatatggc ccatttttag
    40621 caattttttt cattgctttg gcatttctca tgcctcattt attcacacat aaactaattt
    40681 tgggtgctga tgccccattc cattacaatc ggttctatga tgccgcgcaa caaattaaat
    40741 atggggattt ccattatttt ccttcccttt atggattcca gcaaagtggc aggatcgtga
    40801 atgccgttta cggcccattt ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta
    40861 gctggtttca ttatcagatt ctttcaaatt tcattcttta tcttatttca ggattttcta
    40921 tgctgatttt actgagatat gtcaatgttc gaaattgggt aagtgtacca gtagccgttt
    40981 tattcatgag tacgtattct attcaatact ggtctatcaa ccaaggattc actagctggg
    41041 ggacttgttt ttatccttta tgtatgatcc ctattgctga tttcgtcctt cataaaaagt
    41101 tccctgttat caaagtcgct gtctcagtgg gacttatgac acagatccat ttactgtctt
    41161 cgatcatgtt agctttgatg tatatccctt tttatcttta ttactttttt aaccagactg
    41221 aaaaaggaaa agcactgctt caactgatta agtcggtctt gctttatttt gttctgacag
    41281 caaatatttg ggcaggatta gctattgttt acagtgggaa taagattctt cctccctttg
    41341 ttaacagaga aatgagtcaa aaggcgatag atctggatgg cagttattgg ctccattacc
    41401 ctaaggcctt tcctatattg atattatcag gttttttgct ttttattttc tttcaacaaa
    41461 agaacacctt attccaaaaa atcgtgttgt acacaagtct tgttttcttt tttctttcta
    41521 ctagcttgat tccatggacg acattgatcg aaaaaaatgt gccttttatt agtttgatcc
    41581 agtttccatt tcgatttttc gtgccattta cgctattgct tctactttac cttgcccttt
    41641 cactgaacca gtggtctgaa caaaagtggt tccgtctttt aagtatattt ggcattctta
    41701 ttttttcagc acagacgatc cagaacttat accagcatct ggaaaagtgg gaaaatgaaa
    41761 catttgtcag tcgacatact tatctattcg atacgccgga agaagcaagg aaaacattct
    41821 tcagcaaaga tatgtctacc agcttgttcg ttttccaaaa aaccacacct gactatctgc
    41881 caatctataa ggagacaaaa gacaataaat acgaccggta taacgaagaa atactagaaa
    41941 acgaaacaac ttttataaaa acacatccag gcggtctttt gacaatcaag tggaaaaaca
    42001 ctggggacaa aactgttcat atccctgtta tcgtctacga tcggactgtg ctacagcaaa
    42061 atggaaaaac attgactgat tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc
    42121 aaaaaggaat caacgagctc acgcttcatt atcaaacgcc aatctatttc tatttcattc
    42181 tttctcttac tttgattggc tggtttacct tgctatgttt atttatttat catagataca
    42241 agcttttacg tgcttaggca aaagggataa atacatccga tcaaaaaact ctccaaacgg
    42301 tataatcgtt tggagagttt tattttaatc agttttttta tgttatatgt tatatttttt
    42361 attcgttcac atctaattcg atttccaccc cgtagtgatc actgatgatt ggactatcga
    42421 tcccatcaaa aatccgttga tattttttaa cctgcattcc ttcagggacg aaaataaaat
    42481 ctatacgcaa tttttctgta ttttgttccc aaccatctat tttcttttcc acagtagctg
    42541 cttttccttt ttcattcgcg acaacatacg aatcttgaag aagaaggcaa ctttctctta
    42601 cagtataata accttgagag tctactggat tattgaaatc acctaggaaa aaaagtggta
    42661 cgcgagtttc caaaaagtag ttttccaagt ttttccactc aaaataaaag ccactttttt
    42721 tatctgtcca ccaagaaaag tggcagctcg agacaaaaat gtcctgatca tctatctttg
    42781 ttttcccaat caagatcttg cgtgtctgat aatcttcttt cttttgaaat tgggagacgg
    42841 taaggacctg actttccaat gtttttttcg taagcagtgc atttccttct tcatatttat
    42901 cataaccgat gtggctcatt tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa
    42961 gctgaactaa acggtaggca aaattatctt tacggatagg tacttgattc tttaccggac
    43021 agaacttcat tagcttcgca ggttctactt cttcagattc cagtaattgg ttgatttctt
    43081 gtaaagcaat cacttcataa tcttctaaca ggatcttatc tgctaattct tgcaattttt
    43141 tctctggttc tggctcaagc cagctatgcg tgttgagtgt catgaatttc attggttttc
    43201 tccttgtctt catttcgaaa caaaagggtt gtgacaaaat ttttgtcaca acctctccag
    43261 caaatagtgt tctcctgcta actcctcagt aataagctca atggaccagg agctattttt
    43321 tgtttggctg tttttatcac ttggtgcagg gcagcttttt cacgacctct ccactaaaca
    43381 gtattcaaac tgctgcttct cggtaataag cccaaccaaa cgaaaaatag gaggagctat
    43441 ttttgtttgg ctgttcttat gacttgatgc aggacagctt tttcacaacc tctccttaca
    43501 ttttaatgga gccgatcact ttaccagctg tcactgtacc taattgcttg atcactactt
    43561 cttctacttt atcgtttgta aatacgatca tgatcgttgg atctttttct tcgttttgga
    43621 tcacatcaag atccatctca gctaatttcg ttcctgttcc tacttcttgg ccttctttga
    43681 cagcaatctc aaaagctggc tgattcattt ggactgtatc gattcccata tggatcaaaa
    43741 cttcgatacc atctttcgtt tccagcccaa ttgcatgttt gctagggaaa atacttgtca
    43801 cttttccagc gatcggcgca acaacttctc ttgatgttgg aataacagca aagccgtcac
    43861 ccatcatttt ttgtgagaat accggatctt ttacttcaga taaaggaatc acttctccag
    43921 aagctgcgga aactagttct tgttctatac ctaagtattg cttactacct gcttgtccat
    43981 ttcctgtaga aaccatttct ggctctggaa tctctgctcc tgattgcagc agatcttcga
    44041 tatctgattt caagacatct gcttttggtc cataaactgc ttggactcca ttgtctttga
    44101 cgatcaatcc catcgcccct gctcgtttcc aggcttcttc agtccctact ttttctcgat
    44161 catttacact tacgcgtaac cgagtcatac aagcatcgac atctttgata ttttcttttc
    44221 ctcccagcaa atgaatgatc tggaccactt gctgatctgc tgttcctgtt ccgctgttag
    44281 atacaacggt ttcttcactg tcattgtcgt aatttccgtt acgtcccggt gtagcaaagt
    44341 tgaatttttt gatcaagaaa tttgctaaga aatacgtaac aacaccaaaa gcgatcacac
    44401 acaacacgaa gttgataaga tctccaccta gacccgcttt gatagctaac ggtgtccgag
    44461 tcagcaattc gatattccca aatgaatgga cccgcaatgg caagatatct gccatcgcaa
    44521 atgcagcccc ttggatcact gaataaatga catataatgg cacagcagca aacataaaca
    44581 tgaactccaa tggttctgtt acacctgtta gaaagacagc caacgctgct gaaaaataca
    44641 ttgatttata tcttgctttc ttatcaggat cgacattacg atacatcgca aaagccattc
    44701 ccatcaagat acctgaagaa ccaatcattt gtcctacttt gaaacgagcc ggcgtccagt
    44761 tatgcaacac aaactcatat tgcgacatat cccctgcacc tttaagattc actaaatcag
    44821 tggcccaagc caaccataac ggatcttgcc caaatacttg tgtccccgcc tgtgcgcctg
    44881 ataaaatctc atacgatccg ccaagctgtg tatagttgat aggaatcgtc agcatatgat
    44941 gcaatccaaa tggcaatagt aaacgttcta atgttccaaa taaaaacggt gctagaatcg
    45001 gtgcgctttc ttgtgattct gcaatccata aaccaaaatt attgattcca gcctgtacgt
    45061 ttggccacac cacagcaaga atcaatgcca cgattgttga ccataagata acaacaaacg
    45121 gaacaaagcg ctttccattg aaaaatgaca aagcatccgg caattttcta taattatagt
    45181 acttattata agccattgcc ccgacaaatc cagcgatgat ccctacgaat actcccatat
    45241 tcaaagctgg tgcttccaat acacttgtaa aaaatccttt aaccatgatc ttcgtaccga
    45301 acagagtgtg ggtaaatgca tcttcattcg caagcatgtc acttgtgaca ccaaagatag
    45361 ccccagtgat ccgattgatt aaaataaatg agatcccagc tgcaaatgct ccgcctgctc
    45421 tttcttttgc ccaacttcct cctattgcta aagcaaataa aatatgaaga ttaccaataa
    45481 ttgcccaacc aatattttca attactccgc ccgttgtgac aagcggcgtc caatcaggat
    45541 tgatcaaggg aattgatttc cctatactga tcatcaaccc agctgccggc ataactgcta
    45601 ccacaaccat taaagccttt ccaaattttt gccaaaactc aaaactaaat atctttttca
    45661 ttccgtttag ctcctttacg caatcggttt cgttaaacgt attatagcgt gcgttttctt
    45721 ttttgtaaat gctttatttt ttatttttct gtctatacca ttctataaaa cctataatac
    45781 gtgtgttccc ttctataatt ttctcctaaa aatttatttt tttaagcttt tttctatgaa
    45841 atattttctt ttgtctattg acttgtgcaa tcggttgcgt ttattatgaa cgtataaaac
    45901 agctcattag gaggagaaaa atgaaacaga tcaaacgact atttgctatt gatccatgga
    45961 aaatcagcac gacacaatta gataaaaaaa atcttcgact gcaagaatct ttaacaagta
    46021 ttggaaacgg ttatatgggg atgcgcggga actttgaaga aacttactca ggggaccacc
    46081 atcaaggtac ttatttggcg ggtgtctggt atcccgataa gacacgtgtc ggctggtgga
    46141 aaaatggtta tccagaatac tttggaaaag tgatcaacgc cttgaacttt atcgcgatag
    46201 atatttcgat caacgatcag ctgatcgact tggcttcttt ggaaccagaa gacttttact
    46261 gggaattaga tatgaaaaat ggtgtattat ctcgtacatt cacaatcact acttctacta
    46321 ataaagtacg catttccttc gaacgttttc tgagcattgt caaaaaagaa tcagcttata
    46381 tctatttaac tatagaaatg cttgaaggta gcggaacagt caaactcgta tcaaaattgg
    46441 atggaaatgt tcaaaacgaa gacagcaact atgatgaaca tttttggaat gagattgatc
    46501 gtggaactat agaagaaatc ggctatttga cgactaaaac tattccaaac aactttggga
    46561 ttgaacaatt tactgttact gcagcaatgc gccatttcgt taatggaaaa tcagtcatcc
    46621 ctgactatca cgaagatact ttagcattac atggttgctt gtctgcagaa ttatctcaag
    46681 gtgagacatg gtcagtggaa aaagaaatta tcgttcttac tagtagagat attccagaag
    46741 cgcagcaagc agaaaaagct gtctcagaat taacgaacca gacaaacaat tatatccaag
    46801 caaaagaaga gcaaacagcg gcttgggcag aacgatggaa gcttgccgat gtggtcatcg
    46861 aaggagacga agaagcacaa caaggtattc gattcaattt gttccaacta ttctctactt
    46921 actacggcga agatgaacga ttgaatatcg gccccaaagg attcacagga gaaaaatacg
    46981 gcggagccac ttactgggat acagaagcgt atgctgtccc tctttatctt gctttagcca
    47041 aacctgaagt aactaagaat ctgctgaaat atcggcataa tcaactgccg caagcaatcc
    47101 acaacgctca gcaacaagga ttaaaaggcg cgctttatcc tatggtcacc ttcactggtg
    47161 tcgaatgcca taacgagtgg gaaatcacat tcgaggagat tcaccgaaat ggcgcgattg
    47221 cctatgcaat ctacaattat acgaattaca ccggcgatac ggaatatttg aaaaatgaag
    47281 gactggaagt tttagcagaa atcgcacgct tctgggcaga ccgtgtccat ttttcaaaac
    47341 gagcaaataa atacatgatc cacggtgtga ccggcccaaa cgaatatgag aacaatatca
    47401 ataacaattg gtatacaaat acgatcgcag cttgggtctt gcgttacacg cgagaaaatt
    47461 atttaactta tcaaaaagaa gctgctatca ctatcagcga agaagaacta gccaaatgga
    47521 aagatatcgc agagaacatg tacttcccag ttgacgaaga attaggaatc tttgtccagc
    47581 atgacacatt cttagataaa gatctcatgc ctgtatccga tattcccaca agcgatcttc
    47641 ctctgaatca gcattggtct tgggacaaaa tccttagatc ttgcttcatc aagcaggcag
    47701 atgtactaca ggggatttat ttcttcaatg atacttttac aaaagaagaa aagcaaaaaa
    47761 actttgattt ctatgaacca atgactgtcc atgagtcttc cctttcgcca agtatccatt
    47821 cgattttagc agcagaatta ggaatggaaa gcaaagctgt agaaatgtac cagcgaacag
    47881 ctcgcttgga tttggataat tacaataacg acacagaaga cggcttgcac atcacttcca
    47941 tgactggtag ctggttgtcg attgtccaag gatttgctca aatgaaaact gcccatgatc
    48001 agttgagatt cgcaccattt ctgccaaaaa cttggaaagc ttattctttc catatcaatt
    48061 atcgcggacg tttattgttc atctcagtca cagatgaaca agttactttc gagttattag
    48121 aaggttctcc tctagaaatt tacgtctatg aacagtctta ttctttagcg gatcgtctag
    48181 aaataacgct aagaaaggag gaagcaaatg tttaaagggg tattgtttga tttagacggt
    48241 gtcattaccg atactgctga attccattat cgtgcttggc gaaagcttgg tcaggaaatc
    48301 ggcattacga tcgaccacac attcaacgaa cagctaaaag gcgtcagccg agaagactca
    48361 ctctctttgc ttttagctta tggcggaaaa gaacactctt tttcaaagga agaatttgca
    48421 gaattagcga aaagaaaaaa cgattattat ttagagatga tccagacgat cgaaccaaaa
    48481 gatgtcttcc ccggggtcgt gcctttactg gattctttaa aagaagaaaa aatcaagatt
    48541 gctcttgctt ctgcaagtaa aaacgggcca ttcctacttg aaaaaatggg tcttacacct
    48601 tactttgatg ctattgccga cccggcagaa gcaacaaacg gaaaacctgc gccagatatc
    48661 ttcctccttg cagcaaaagc tgtcggacta aaagcagaag aatgtatcgg gatcgaagac
    48721 gcgcaagccg gtatccaagc catcctctca agtggcgctc aaccaattgg cgtgggacgt
    48781 gctgaagacc ttggagagga gatcccgctt gtccctgata cgacttttct tacgatcgat
    48841 tacttgaaag aaaagtggca tgaccatgga taatccagag atctccgtcg taccagttcc
    48901 agagactgaa ataaagaaaa tcacattgaa gaacgactac ttagaagtcg ttcttctcaa
    48961 ttacggtgcc cgcctgcacc aaatcttcgc accagacaaa gaaggaaaat cagaaaatgt
    49021 tttattgtct tacgatcgtt tcgaagatgt tctaacagac aaaagctttt ttggagcaac
    49081 tgtcggacct gtagccggaa ggatccggga tgcttcttgg ggtgagcata gattggagaa
    49141 aaactgcgga tcacaccata tccacggtgg cacgaaaggc tggtctttcc aattttggga
    49201 agtagaagtt ttcaaaactc catcatcaat aggtgtggtc ttttacttaa aagatgaatt
    49261 ttctacctat ccaggaccaa tcactgctac gatcacttac cgtttaacaa aaaacgaatt
    49321 agagatgaca acctctgcta gtagccttgt tgaaaccatc tgcaatccga ccaaccatgc
    49381 ctacttcaac ctttcaggaa atggaacaag agacatctat gaacatcagt taacggtctt
    49441 tttagatggt gtgcttgaat tagatcaaga aaaactgcct actggaaatt ggacaaaaaa
    49501 agaaaaactg ccaatcgact ttagaaaatc cccaacactg caagagatcc ttgcatgtta
    49561 tccagatgga ctagatgatg tatttctttt gcatcatcct aggctttcca aaacttcctt
    49621 acaattattc gagaagcatt ctggtcgcca aatgactata gcaacttcta ataaaagtat
    49681 ggtattattt tctacgactg gattcgaagc tgatttctct gtcaatggaa aacagatgca
    49741 ttcaaactac ggattagcaa tcgaaccgca agaaatccct gatatcgttc atttccccaa
    49801 atttggatcg atcaacctcc atcctggtca agaacggatc agtcagacga tttatcggtt
    49861 ctctgcacaa taacaagaga aaggtgtttt tatcatggct attaccgtaa aagatgtggc
    49921 gaaaaaagcc ggtgttgcca cctcgaccgt ctctcgtgtc atcaacgatc atcctagtat
    49981 ttccgagaca acaaagaaga aagtccgaaa aattatggat gaactaggtt atgttcctaa
    50041 catgactgcc cgcaatctag gaaaacgcat ttccagtgcc atcggcgtaa tcttaccccc
    50101 tcttgattca aaagagcgga tcggtaaccc attttatctt gagatcatgg aagcaatcaa
    50161 cgaagaagcg cggaattatg atatgactac agcaatcgct actgctaaaa attttgaatt
    50221 gctgttagag aacgtccagc gtatgcattt acaaaaacaa gtagatggtt ttattctagt
    50281 gtattcagat agtcaagata ctgtcattga ttatttatac caaaaccaca tccctttcac
    50341 tttgatcgga cagccttatc atcatgagaa cgaaatcgtt tatgtagata atgataacca
    50401 gcttctaggt aaacaagcaa cagaattttt gatccagaat ggacataaga atatcctgtt
    50461 tgtgacaaac acgactcatg aaagtttgta tttcgaacga tatttcggtt atcaaaaagc
    50521 aatgatgatg gctggtcttc ctgcgttatc cagtgtagta ctagagcatc cggaggatta
    50581 tctgtccttt gagaaaacgt tgaaagaaaa cgaagccaca gcattggtgg tcattgacga
    50641 tatcttcgcc cttcgcacga tgcagttggc gcaaatgtat ggctatgtca ttccagagac
    50701 actctccgtc attagcttca acaactcgat cttctcaaca ttaacacacc cttaccttac
    50761 aagtatcgat atcgatatct ccgaattagg acgtgtcgct atgcaaaagc tgcgcgaatt
    50821 gatccatgaa gaattgagca gtggcgtacg tttggtcatc cctcatcgct tgatcaaaag
    50881 agagacagtc gttcctttag aaaacccata ctaaatagct gactcactaa atacgctgac
    50941 catttatcct atggtcagct ttttatgtaa aagaagatac tacttctaac acattgttta
    51001 tctgtaaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
    51061 tataaacggc ggaagcagaa gcaactcctt cggaaataag ctgaaattca caaaaattta
    51121 aaaagcaatt ttcttgagtt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
    51181 cttttttcct tccttcaatt ttttacacgt cgacgattca ataaaaaacc gcctaatatt
    51241 gtaaagacag gtgcaagaat cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact
    51301 ttcatcgttc ccataatgaa tgtgccgctg actccccacg gtacgagaga attgacggtc
    51361 gcacctgaat ccgctagtgt tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa
    51421 gaacgcttga atgtttctcc tggaagaatg atggacagat actgttctcc aacgatcaga
    51481 ttgattccga tacagctcaa ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt
    51541 tcttttaatt cttgaacgat ggtatcaacg atcagatatt tgatcagtaa cccacctaat
    51601 gccaatgcaa gtaaaatcaa actagcagaa cctaacatac tcatgatccc gcctcgagaa
    51661 agcagttcat ctagctttgg atcaggtgta tttgcgacat aaccattcat caagatgtct
    51721 gctgcttttc cgaccgtcaa acttttctca tggataaaag aaagaacgag agcagctgtc
    51781 gatcccgcta gtaatgtagg gatagccgga atttttttga ttgccccccc aaataaaata
    51841 actagtggaa tcaatgtcca aggagagatc caaaagctcg ctttcatgtt ttggatcatt
    51901 tcattgatac tagctagatc ggctgaatga ctgttatgtc ctaatatcgt ataaaaaatc
    51961 aacgaaagga cgaatgctgg gaaatccgta taacgcatac cagcgatatg ttcgaataga
    52021 ttaactcctc caatacccgc tgccaagttg gtcgtatctg ataaaggcga gcagttattc
    52081 cctaaaaagg caccggaaac gactgcgcct gtagtcattg catcattgaa tccaagtaaa
    52141 tgaccgatcc ccaaaaaagc aattccaatc gtcgaaatcg ttgtaaatga actgccgaca
    52201 gtcactccga caattgcaca aacaagaaat gctgtcggta aaaagaaacg cacagaaaca
    52261 agtttaaatc cataaaccat aatcgtaggg atggttccag ataaaatcca tgaagcaact
    52321 aagacaccaa tcaaaagaaa aatcaggatt ggaatgatcc ctggagtgat tcctttgatg
    52381 atcccgtcat ggatctcatc ccatgtgaac tttttaaatc tgccataaaa caacaaacac
    52441 atgaaagctg caaggatcgg gatatgtggc gagagctgga atccgatgat cagtactcct
    52501 aggagtgcca acaacacgat caatacagcg atactttctt ttaaagaaat atttttattc
    52561 atcgtcgatc tcctatttca aatgaaaagg ccctgccatg aaaaaactat tcacttggca
    52621 ggacctccta ctaaatcagc gacaaaacgt cggctgaaag acttattttt ttatttttct
    52681 tctaaacttt tttctacctc aatcccccaa gaatctttct tgaagtgatt gatgatcaat
    52741 ggaataacga acatgaccac tgtgatagct gctactaata atgcatcact caatgtcgct
    52801 gtacctaatg tagcaaatac gacaacgatg atagagaaga tcagcatgca gctgactacc
    52861 caagctaatc cgtttccgtt tttaccaatt cggtaaggac gttcgaattc tggatgtttc
    52921 ttacgcattt taagcaatga aacagcaatc aaaatgtaca cgatacaata aataacagtt
    52981 gtagcatttg taagtgtcaa gaatacagca cttacgtcat ccattacacc ataaagcaaa
    53041 gcaaataatg aaataacgat tgattgtgtt agaacgacat ttctagatac gccgtatttg
    53101 ttttctttat ggaatccgaa ttttggtgga aggaatcctt cacgagctac ttggatgatt
    53161 gtttttgatg gtccagtaac ccaagctgat aattgtaaaa gcacaccaat aaataccatg
    53221 aagctgaaga tatttccgat cacttctggt aagcctagga tttgacagtc aatcaagata
    53281 ggctgcgtga tatttgctaa ttccattttt ccatctggta cgacatttgc tacaagcatc
    53341 gcattgatga cattcaataa aactaatccg atcaaagcga taaatacgcc ttttgtataa
    53401 ttttttgttg cgtctttcaa acgaggcatg taaacagaac tcatttcgat cccaacaaaa
    53461 ataaatgtga taccagctaa gtatttcaat gaatcaatat gttccaagtc agggaaagct
    53521 tttgaccatg aaaagtcacc tagatagccg tttgagacta gtccgacttt gaaggctgcc
    53581 aaaacaccta aaacgaacat gatgactact gggatatata cccctagcca tacaccgatg
    53641 ttcccgccga cttttgccat atcgaatttc aagttcaaga tcgtgatgat ccagtagata
    53701 actaaaatac aacctaaaac gaaccagtga ttattgccaa gttctacatt accaaatgtg
    53761 tttcctaaca atggtcctaa agtagaagcg accattacca tacctgggaa catttgcacc
    53821 cataatagcc atgcaacgac aaatccccat ttgctgccca gtgctgtttt tacccataac
    53881 tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac cggaaaccat tgatatcgga
    53941 ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca atgtccaacc gactgcggct
    54001 aacgtaggaa tactccgaac cgttgcacac agtgccattg tcagaccgat aaaggtccca
    54061 agacccattt tacttacttc agatttactc accgttgaca ctctccttga ttttttggat
    54121 aaaataacgg tgtctttgaa gtagtttcag caataaacga aacaattcag cgaatatttg
    54181 aggggattct ttgagtttat tgcttgaagg gtttcttcaa agacaacctc aaaacaaagg
    54241 gatcgaagag cttaggtctc cccttgctct tcagatccaa acatgcgtca gaaacagtta
    54301 gtattcaagc tgttttctaa catgattacc ttgcttattt tgcttcgctt gccaataatt
    54361 ggtctgcgta gattttttcc aatttttctt gaagagctgc tttgattttt tcagcatatt
    54421 cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac gctggcacgc aatacagtta
    54481 cttttccggc acggttccat tcttcatctg agaatcctag ttggttcaca aattgtaatg
    54541 ggctgttgcc atagtctggg atagcaaagt cagtatgtga agttaagaac tcattaccgt
    54601 aaatgcttcc tttcacgtat gaagaataat catatacgtc atggttcaat ttattcattg
    54661 caactaagtc atcgttgcct ttttctttga atacatagtc taccatattg aaatctggat
    54721 aagttaatgg atgaacttcg atttctttgt ctcctacttt aaatgacaag tcattcaaga
    54781 agttgtagaa acgatgtgca ccttcgattg atgcacccat taatttacca tatcctgtga
    54841 cattcaaagg taagacatgg tgtgctgccc aaacgctggc tgctgttgcc cctgcttttg
    54901 aaccttccaa gatataagcc ccaagtaatg ctgggatatc tgcgcctttt tcaaatacat
    54961 atgtcgcaaa gtaagagata acgtctctca tgcggatatc tttgatgacg ataccaccgg
    55021 cagaatatgg aacatagccc attttatgtg ggtcaatcgt tacagattct gcttcttcga
    55081 ttgctttata tgcactgtgt acttcttcta agatataatc tttgttttct gtaaagacat
    55141 tgtatttgta atgaacatct tttaaatctt caaatggaat gaagttgttg tcttcgtcta
    55201 agaaaatcgc acggccgtat ccgccataag cagcatctac gtgtaagtag aagtaaatac
    55261 cgtctttttc taatacgcga cgcaatgcaa cgattttatc gataccgtcg attgctcctt
    55321 cttctgttga tcctacaaca ccgactacac ctaggattgg tgttttttca gctgctagac
    55381 cacgaacgat tttttcaagt tcgttgatgt ccatgcgata gttgtggtca actggcactg
    55441 gaatcacttg gtctaaaccg ataccgatga tgtcggcagc ttttagccat gaatagtgtt
    55501 tagtttgtgg aaccaaccat tttcctaatt tttctaaatg ttttccgcta cgtgctgagt
    55561 gagctttgat ttcgtcgatt ttttctggga cgctgtctaa cagattcatg atttcttctg
    55621 ttgacaagtt cattaattcc caatcgcttt ttccagcaac tagttcaggt gtcacttctt
    55681 tcattgcaag cggcaatgat ttgatgttgc gggcatacca aagtccttct aagtttgcta
    55741 aagaaccatc agcaacgatg tggccccagc catctttata gctcattaat tttgcaaatt
    55801 ccattcctac ttcttcttcc atttggcttg ttgcaggaga agattcatag gcaacgttat
    55861 taccattcca tagcatagca aaattgtacg ctagtaaaga tggcatcaat gtttcagagt
    55921 tcatatgacc ccagtaacgt ccggcattat gccaaggaac ggaatgggta cgcatccgcg
    55981 ctgaaatttc tgatagaaca tcctttgttt tattcacagt gtgttcaaaa ctagcactgc
    56041 ttttttcttc tggcgtaata ataggcatgt cttgaggcat gtagttttga cgccagccta
    56101 aatgttcatc caccaattca ttcaacaaag ctttatagat ttggccgttc tcagctttgt
    56161 ccccaatgaa tagggcattt aggtttagat ctttcgacaa tgattcactc atagtgaaac
    56221 cctcctaaaa aaatatttaa attttgtcga gccctacatt acacctgttc ttctattctg
    56281 taaactaagt tttggcctga tttttaatca tattttaata tgtatcaatt atccgaattg
    56341 ttcacacttt tgaaataatt aaaaaaaacg agggaattta caaatgtaaa ctccctcgca
    56401 aagattgtat taacgacaac cagcgttcta ttttaggatg ggtttcaaaa ttggaatgtt
    56461 gtaatagtat ttcccttttt caaggtaaaa acttactaaa ttctaatcaa ttactttggc
    56521 caaaaagtaa tttttcttac cttttcgaat aaccacaaac ttaccatcga attcatcgga
    56581 tggatttatg acaaaattta aatcggtaac gcggtcaccg ttaatactta tagctccgtt
    56641 tgaaacatct tcacgtgctt gacgtttaga tggttcaatt tttgtggaaa caagcagttc
    56701 cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc attttaccga atccttgcgc
    56761 gatttcttcc gcatttagtt ctttaatatt tccagagaac aatgcttgcg ttattttttg
    56821 cgcttctttc aagtcttctt cactatgcac aaatcttgta acttcttctg ccaaacggcg
    56881 ttgtgcttca cgtttctcag gttctgtctc tacttttttc gctaagtctt cgatttcttc
    56941 ttgagacaag aaagtaaaga atttcaagta tttcactaca tcgcgatcat cttgattcaa
    57001 ccagaattgg tagaactcaa atggtgaagt tttcttcgga tcaagccaaa cggcaccgcc
    57061 tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc aatgggatcg ttaaaccgaa
    57121 cgcttctgct tctggtcctt ctaattttcg gattaggtct aatccagctg tgatatttcc
    57181 ccattggtct gctccaccga tttgcaattg cacatcgtat gttttatgca gatgcaaaaa
    57241 gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat gagattccta cttccaaacg
    57301 gctggcaacg atatcttttg ctaacatcgt gttgatgttg aagtttttac cgtagtctct
    57361 caaaaattca agtaaagaga tttttgacaa ccagtcgtag ttgttcacaa atgtgatatt
    57421 tgcatcttta ccaaacaatt ttctcatttg attggaaagt gcgtccacgt tatgttgcac
    57481 ttgttccatc gtttgcaaca cacgttctgt tttgcggccg cttgggtcgc cgatcgttcc
    57541 tgttccgccg ccaatcagaa tatatggatg atggcctgcc aattggaatc ttttcatcat
    57601 cataaatgga atcaaatgtc cgatatgcat cgaatcacca gttggatcaa cgccgcaata
    57661 aagtgaaatg ctcttttctt caacgagctc gcgaagtctt tcttcgtttg tttgctgatt
    57721 aatggcgtcg cgccaagtta attcatcaat aatattcatt ttactgacct ccgtgtagtt
    57781 tttttatgaa agcaggaacc tgctagcata tgtaattaat tatttcttca ggataggata
    57841 ggaaataaaa aaagtccctt ggcatataag ccaagggacg aaatctcgcg gtaccaccca
    57901 atttgtatgt ctagatatcc aacatacctc tcgaacattt aacgctgtcg cgtggcaatc
    57961 actgccaaag actcctgaaa tgtaattcgc tttaaagcat gtactggttt gcagcgacca
    58021 ccagctttct gaaacattgg ctttaacaac tacttcgttt cgatcttcgt cttgttatta
    58081 ttaatatgtg tctatcatag agcgcaactt tttctttgtc aacagaaaaa ggatattttt
    58141 tttaaattcc tcattttttc ttttttgaat ccgctctaat tccgaacatt ttattttcaa
    58201 ttattgttaa aagaaataac tttttctgta ttttttctgc aatttatcga gaagtcactt
    58261 tactttgcct cttattcttt cttcgttaca ataaggaatg ggacaagtaa aaaaatgaaa
    58321 aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta ttttaggagc cacttctgct
    58381 ttaactatcg ttattttaat tctaagtttg ttttttgtca tccgatcatc tacaaaaaaa
    58441 gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa aagaaccgac agatgataag
    58501 caacaactag ttactcaagc aaaaaatctg gctcaaagct acgattatga ccaagcgatt
    58561 gcgttattgg aaaaagatag taagaacgga tctactgaaa cacaacagct tcttcaaaca
    58621 ctaaaaaagg agaaagaaca actgatcgac tggtctgatc ctactcagat ctctcatgtc
    58681 tttttccaca gcttgatcgt ggacccgcaa aaagccttcc actctcaaca ggcacaagga
    58741 tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt cgatcgaaca actttatcaa
    58801 aatgattttg ttttagttaa tttgaatgat ttgatccaaa aagacgaaca aggaaatctt
    58861 tcctttaacg ggcttgcgct acctgaagga aaaaaaccat tggttctttc acaagatgat
    58921 gtcagctatt atgaatatat ggataattcc ggttttccta gccgattggt cgtatcaaat
    58981 aacaatgaaa tcaaaaatgt ctataaagag aaagataaag aagaaatcgg tgactttgac
    59041 atggttcctc tgatcgatgc ctttgtcaag aaacatcctg atttttctta tcgaggcgca
    59101 aaaggtacct tggccctgac aggttacaac ggagttttag gttatcgaac atcaaaatct
    59161 caatatggag acaatgaaaa aacaaaaaaa gagattaaag aagctaaaaa agtggcggaa
    59221 cagttgaaga aagacggctg gagctttgct tcccatacat ggggtcactt gaatatgact
    59281 caagcttcac tagaagatgt aaaaaaagac aatgaattgt ggcagcaaga agttgcacct
    59341 atcctaggaa aaacaaatat tctgatttat ccatttggtg cagacatcag cgactggcag
    59401 ccttattcag cagaaaatca aaaatttgct tacttgaaga gtcaaggttt cgatattttc
    59461 tgtaatgtcg atgcttctac accagcttgg ggacaattag gtacggattt ctatcgaaat
    59521 gctcggatca atatcgatgg cattcgtttt caatctgatt tagacggaaa aaatcctatt
    59581 cttgatccat tcatcaatgt ccatgatgtc tatgacaaag aagcacgcga atctgcttga
    59641 ttttacgtca tttatgaacc aaaaaagccg aactgacatt ttatcgtcag tttcggcttt
    59701 tttatgcttt atttcttctt cggtgcgatt cccttgatca ggacttctgt ccattctgct
    59761 gtatatggaa gcagttttgc gtatatctcc ggcttagaaa ttccttctac cattgcttga
    59821 aaatagagga tcaagaactc atccgaatat ttcaaatcca cttttccttc tttccgccct
    59881 cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg tatacgcatc catcgcgtca
    59941 gaaaattctt ttttttcttt ttttgtatag tatgtcatca aatcgatata aaattgtttg
    60001 ttcactcgat tgagataacg gattttgttt tcactcatgg caatcagtgt ttcttcaaat
    60061 ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta aatcattcat aaatgcaaaa
    60121 aatacttcat aaatcagccc ttccttgctg ccaaaatatt taaaaatcgt cgctttactt
    60181 acctgagcgt tctcagctac cttatccatt gtcactccag cggttcctat gtctgtgttc
    60241 atcaagtcaa aagctgcttg taaaatctct ttctttttct cttgtgctct cttttcaaaa
    60301 ccgttcattt gtagagcctc ccgtaatttt aaacttttat aatatatata gttcaaattt
    60361 attctgaggt ttattataac tatctattga gaaagtatca agctagcaat tccttgttta
    60421 tgaattcatt gacagaaatt tataaaaaga atattatgta ctaaaataat aaaaaaagtt
    60481 ttataaaaag gtataaaacc tttttattaa actatttaat cttgtttagt atatattttt
    60541 agaaaaagga gtggggtttt tatggcagaa atcgtcaaag tcacacattt gaaaaagagc
    60601 tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg tacattcagg tgaagtcgtt
    60661 ggatttatcg gaccaaatgg ttctggaaaa tccacgacga ttcggacact tttagggatt
    60721 ataaaaaaag acggcggaac ggcaacgatt tttgggcaag atgtatggga agatagttta
    60781 tctatccatg aacgtctttc ttatgttcca ggcgatatct ctttgtgggg aaatttgact
    60841 ggaggagcga tcatcgatct cttcatgaag cttcatggaa aagggagtgc tcaaaaaaaa
    60901 gatgaactga ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa ctattcaaaa
    60961 ggaaatcgcc aaaaagtggg cttgattgct gctttggctg ttgattcgga tctctattta
    61021 tttgatgagc ctacttctgg tttagatcct ttgatggaaa cgattttcca agaagaagtt
    61081 gaaaaattga aagaacaggg caaatccatc ctactttctt ctcatattct cagtgaagtc
    61141 gagcgactag cggataaagt cgtgatcata cgcgaaggaa cactcgatga agaaggaaca
    61201 ctcgatgaat tgcgtcattt gactcgttcg accatcacta tagaaacaga agcagagaat
    61261 agtcacttag cacaattgaa cggtgtccat gactttgtgc aaaaaggtca cctcgctcaa
    61321 tttgctgctg ataacgaagc tttcgatgtg attttagctg aagcgtccaa attaggtgtg
    61381 aaaaaatttg aatctattcc accgactctt gaggatttat tcatgagaca ttatgaagga
    61441 tgaggaggaa gcgaaatgac tgataaattt tcacgctggt ccaccctttt ttctcaaaac
    61501 cttagccgtg actggaaaaa gatcctgata tggctagtcg gtgtcactgc tttttctggt
    61561 ggttttgtcc ctgcgtttga agaattgact tccggacaag gattagctgg attatacgaa
    61621 accttgcaaa acccggcaat gattgcaatg gtcggaccaa ctccagcttc gaatgctgct
    61681 gagtatactt taggagcgat gtatgcaaat gaaatgttgc ttttttgcag tttgtttgct
    61741 gctgtgatct ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga acttggtctg
    61801 attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc tgtcatcgct
    61861 gaaagtattc tgatcaattt gcttttagca atatcgatca gctgtacgat gatttttttc
    61921 caagcggatt cgatcactgc agaaggtgct tggctttttg ggctatctgt aggtagtatg
    61981 gggattttgg ggagtgccgt tgcactgttt gctgcacaac tgatgccaag ttcagccagt
    62041 tcgaatggtc tgtctttagc gtttttaggt ggactttacc ttctacgagc aataacagat
    62101 gtagctgatt cctccctttc gatgtggaat cctttaggct ggtcttattt gacctatcca
    62161 tttacaacta acaactggat tcctttgctt tatttgtttt tgttcagtct aatcttgata
    62221 atcagttcat ttgttttaga ggaacatcga gatttgaaca ccggctatat ccccgaacgt
    62281 gaaggaaaac cgtatgctaa acgttctctt ttatccttgc gtggtttatt attctatcta
    62341 aataaaggga tgacaatcag ttggcttatc acttttggtt tgatgggggc ggcatacggc
    62401 tctatctacg ggaatatgca acagttttta gaaagtaacg acttaatgaa acagatgttt
    62461 atccaatctg gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt agtcttgatt
    62521 tgtctagctg ctattttacc aattgctagc atcaatcgtt tatttacaga agaaacccac
    62581 ggacgtatga atcagctgtt cgcaacaaaa atttctagga accaacttta ttggaccaat
    62641 atgttactag ctattctatt tgctatattg gcaatcctga ttagttctgg tgcactaggg
    62701 ctttctgctt tggcttcgat gaaggatgcg aaagacatgg atctattgat gtttcttaaa
    62761 gccgggttca atttcctgcc tgccgtttta gtgtttatcg gaattagtgg ctttctattc
    62821 ggatggcttc ctcgaatcgg taaacttgct tatatctact tagcttactc ctttgcactc
    62881 aattactttg gcggaatttt ggatttacca gaatggtttt ccaaaacagc tgtccctagc
    62941 tgggttccac ggatgccaaa cgattctttt gatctttccg tgttccttac gttatcatgt
    63001 atcagccttg cactgttcgt ccttggttct attggttata ggcgaagaga cttactagaa
    63061 ggataataaa aaagcatgta caatttcatg ctagcctcca aatctgggtc aaaaatccaa
    63121 catttggagg tcattttttt atttacaagt cttctaactg ctctttatca atgatccaga
    63181 cttctcgatt ctttcttttt acataaccat tctcctctaa taatttaaat tttctagata
    63241 aagtttcggg ggtcgtaccg ataaatgcag caagttcttt cattttcatt ggcaggaaaa
    63301 agtgatcctt ccctgtcgct ttagctaagt caagcagata gagagcgact cgttcttcta
    63361 ctttttccat catcaaaaaa gttgtctgct gctgtacttt tgttaatttc tcaacgttga
    63421 ttgctaaaag tttcagacta agggcgggat aatgcagtaa gagttccgag aaatcttttt
    63481 gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc aaataaagac tcatttggaa
    63541 cgcctagcaa ctggctctct ccctcatatc cgcccggctc tattactcgt aaaagctgtt
    63601 cctttccgct agcagataat tgatacactt tcatactgcc ggaggccacg atcactaatt
    63661 gaggttctcc attcggcgca agaatctgtt ctcctttttc cacatagtga tgtttgacaa
    63721 gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt gaacaaagga acaaatgaaa
    63781 cacataaatg atcatgactc ataatctctc ctccttctaa acagctattt ctaataaaga
    63841 aacataactt cccttattcc aactgataat tttcttttat catagcataa acgtcaagcg
    63901 aaccagatac cagcaaatag agtggatttc tttttgtccc ttgctttatt ttccttcttt
    63961 tgagacctta agtaattgat tcctatcaat tttttaaata tttacttttt gaataatcaa
    64021 aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc ttatttcgtg
    64081 ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt tcttgtaagg
    64141 tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat agtttaccca
    64201 tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt gtatcggaca
    64261 aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc catatgtaat
    64321 aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac tggttatacg
    64381 ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa tagatttggt
    64441 attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga gattcgcttc
    64501 ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt tcgattttag
    64561 gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga atctctttcc
    64621 atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct gttggatggc
    64681 tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa tctgattttc
    64741 caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa ttttgcgata
    64801 tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac agccaaacaa
    64861 aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga tcacatctaa
    64921 aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc cgattgcacg
    64981 ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt gttcttttgc
    65041 ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga ctggcagcca
    65101 aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa tacccgctgt
    65161 tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga cctcttttgt
    65221 cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc caccgacttt
    65281 cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag gatgatcggc
    65341 ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat ggtctccatc
    65401 gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg cctctgcaaa
    65461 ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac ccttttatct
    65521 tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt tccattgtgt
    65581 ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg tcataaaatt
    65641 accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta aaacatcatt
    65701 catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta gtacacctgc
    65761 ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct ttgccagtac
    65821 tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac caacaccata
    65881 ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta cagttgctgc
    65941 tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca gttctttcaa
    66001 ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta caaggacagt
    66061 acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga tatcatcatc
    66121 tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg ccatatcgaa
    66181 gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc cactatcggc
    66241 ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat caccaagcac
    66301 cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat gtccgcttcc
    66361 tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa cacgggaaga
    66421 ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca tttcttcgac
    66481 aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc tttccggcat
    66541 tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg atggctgctg
    66601 caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc tgctcttctt
    66661 ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc gcaaaaacaa
    66721 aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc gggtctgatc
    66781 cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat ttttgcatct
    66841 gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata agcaaaatac
    66901 tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt ttcgctttca
    66961 ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg tgtagtgctt
    67021 cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta caacaacaac
    67081 gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg gtgaggtcat
    67141 tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct ttggcggccg
    67201 ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg ccgaaatggc
    67261 cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg actatgaagt
    67321 attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg tctccacgag
    67381 ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag tggcactcaa
    67441 gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct cttttttatt
    67501 tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct gctaaggaat
    67561 aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt gatttggatg
    67621 gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat ttttctcctg
    67681 ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct ttttttgctt
    67741 caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct tgactggccg
    67801 ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca acctgattta
    67861 attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt tggacagctt
    67921 ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca tttcccactt
    67981 tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc aatttgtttt
    68041 ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct tgcaaatgat
    68101 cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat gaaatcgttt
    68161 ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca ccgttttcag
    68221 caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa gtttccgcaa
    68281 aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt aacggcttca
    68341 ttcttttttt catcactttt cccatcctta ctacttttta actaatttct tattataagc
    68401 aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac ggtgcatctt
    68461 ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta aaatcgtttt
    68521 gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga acaaaagcat
    68581 atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta caatcagcga
    68641 agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa aactgaatgt
    68701 aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga ttaatccagc
    68761 aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg tttgatcaat
    68821 gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt tgaaattcgt
    68881 cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata gcatcttcaa
    68941 cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata accagtcatt
    69001 taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc tgaatccgcc
    69061 cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg cataaagacc
    69121 accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga attcaaccgt
    69181 ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag tgaccgcagc
    69241 aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg catctggctc
    69301 cggtaccgtg tctgcatcat tgcttaaaat caatttccct tttgcaaagg caagtccgat
    69361 attaaacgcg tgggcttttc ctttattttt ttcgatccga accacacgaa gattagcgta
    69421 ttttttcatc agtctagcta atatttctgg tgtttggtcc gttgaaccat cgtctgtcac
    69481 taatacctca tagttgtgat aattcaattt cgtcatcaaa tactcgattg tatattcgat
    69541 cacaatttct tcattatggg ctggcaccat gatcgtgatg aacggttcga cactcaaggg
    69601 aacatctacc cattcttttt gcttatgttt gtataaaaac acataacacc agacaccaat
    69661 aaaccataca aatccgccta aaatcggata agaaacgaga aaaaaataca taatagacaa
    69721 acaagtatct aagaataaat tacctgtatg ggtgattgag atcatttcag ttccacccca
    69781 ttttctttat acaaatctgc aatgaatgtc gtatctagat ttttctcttc ggagacagaa
    69841 taaaaacgga ccgtttctct ctcttctttt gttccaaaac gttccgtata cacttcttca
    69901 agtaattctt gtcttttttt caatttttca tcttcatatt caaaagattt atttactttt
    69961 ttgtatagat ttcgattgtt ccacctagtc aatacaaatg aggtaatcag gaaactgaaa
    70021 aaaatcaata caaaaaagcc gattaagaaa tacagcattt tcttttctga taaaaaagcg
    70081 tacaaggaaa aatccttggc tctttctggt ctcgttaatg ggaaaaagac ccatataaaa
    70141 ggaagaacaa cgatcatcca tcctaaaaga gccactaacg tttgccaaat ctttaaccag
    70201 taattacctt ttgaaaaata cttatctttc accaaaattg atgcaacttc ttctcttgtt
    70261 acttttttca tatcctcacc tcacgttttt ttgttacgac gtaggagttt accatacatt
    70321 tcatttcttt tcacataaag tgttcctaaa tttttcctaa gaaaaagaac aaaacatttc
    70381 tcatcagcaa atgaaaaata ttttgttctt tttatcagtt gttcttttta ttttttatct
    70441 cttaattatg ttgctctttc caatacgaca atgcttttca ttcctctaga tatcgccgtg
    70501 tacatttgtc tgcgtcttct ttgctcatct ccatcgtttt caaatggata taagattaca
    70561 tgatcaaatt ccagtccttt tgctagactc aaaggaatga tttggcagtt ttctaatcca
    70621 tatgaatttt ttttaatcga ttcttgtagc gtttgggttt cctcttctgt ttgggtgata
    70681 actgccgctt tttctccttt tagagaaacc aaaatctcag ctagtatttt caacaattct
    70741 tcagaggatc gaaaagagcg gtattcgggt tcttttcctt gcggtcggat cgatacgatg
    70801 tcgatcttct cttgatccac agcataggtt ttgaaaagct ctgtgattgc tccgctagaa
    70861 cggtaactat ttctaagatc ataccgatgg atcggcagat ggtagtcgtc gaaacaacgc
    70921 ataatatcag caaaagtagt ggaagaatta aagattgcct gattctcgtc acctactaaa
    70981 gtaaagtgag tttttggaaa taattcgatc aatagaccta attgtgccag ggtataatct
    71041 tgtacttcat caatcaatag atagcgaaat gctggtacat ttaccttttc aacaagtaaa
    71101 tgacgaatag ctaatataat gactgcttca tcaacagtac gtgtgggttg ccaagcataa
    71161 gctgagccat atcgtttttc ataaattctt tcaaacaact gatgctcatc cacccatgcc
    71221 atttcttcga tttgtctggt tatttttcga tatttttttt gtaaaagttt ccttgcataa
    71281 gctacaatac tttgttccga atcatcagaa atcaatttac cgaataattc caactgccta
    71341 tcttctgtca acgagagtac ctgattctgc acagcaggac tttttgcttg tttcaaaaga
    71401 tgattcttcc attcgctcat cagtgccttt ttcgttgctt gaagcctatc gatcaattta
    71461 ggatgagcag gaactttctc atatattttt tcgatcgttt ttttagaaag gactgttttt
    71521 ccatttttag taagtccacg gataaaattc ggatgatcta aaaacaaagg atctgattgt
    71581 tttagattat cgataaactt tttgctacgc aaacgttctg tctgctccga tacattttct
    71641 cccgtgatac gtttgaaata agcctcttca ccttctattt cctctgctga aagctgtgaa
    71701 accagctgta tgatggttag attcagtgga tttctttcac ctaatgatgg taggacattc
    71761 gaaatatagt cgataaaccg atgattaggt gatagaatca gcaagtcatc ggatgtcatc
    71821 gtatctcgat ataaatagag cagatacgca atacgctgca tgatagcaga ggttttacca
    71881 cttcctgcta cgccatttac caagatattt tgacttttca catcccgaat gattgtgttt
    71941 tgttccgatt ggatcgtagc agtgatagcc ttcatttcat tggtctcatc ttggcctaag
    72001 acttctaata atacgtcatc ttgaatagct acagacgtat caaaaaactt gaccaaacga
    72061 tctctttcca aaagaaattg tcgtctttct ttaataaccg tatcgatttt attttgacga
    72121 accgtataag aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat tggtgaacgc
    72181 caatcataaa caagattttc atctgcatca tctgtgaaat ttgctgtacc gatataaaag
    72241 gattcttttg gctcattatc cagaaagtct acaacgactt ttccaaagta gggacttttc
    72301 aataaacgtt cgatctttgc tagctgattt tctgcgtttt tctgtttgat attcatctga
    72361 tcgatttctc tatttttcat ttcaatcatc gaaaaagtat ccaggttatc taagtaactg
    72421 tcaaaattca atcgaagctc gccagccatt tctttcaacg actggtttcc ttctattttt
    72481 gccgtatcca tcgattcccg cagttcgttt tttttatcaa ttagcttttg atacacgttc
    72541 ttcagatatg cttcttctaa ctgtttttgt gtgttgacca tacacattct cctctttttt
    72601 taaagtggtg gaaccgatta gtttacctct tttaagagtc gaatgcaagc tttttaacga
    72661 gtatcatttg ttaggatata tcagttcttc aggtcggaca gtttgatata aagaaaatgc
    72721 accatcaagg ttttttacgt ggtagccaga ctgcttcaag attctttccg ctagatagct
    72781 acgtaatccg ctatgacagc tgacgatata ttcttgttgg ctgtctaatt catttaatcg
    72841 gtcccgaagt tcattcaaag ggatatgttt ggcttccttg aatttgccct tttccaattc
    72901 ttctgctgtt cgcacatcta ataaaatttt tccttttgct agttctgtcg gcaattcatg
    72961 ccattgtacg gtttcactaa gcccttctgc aatgttcatt gctgcatatc ctagcatgtt
    73021 tactggatct ttggctgagc caaatggcgg tgcatacgtc aattctaatt ccggtaaatc
    73081 gaagatcgtc aaatgccctt tgattgctgt tgctaaaata tcgatccgtt tatccacacc
    73141 ttttgcccca acaccttgtg caccataaat ctcgccagtc tctggatgga agatcaactt
    73201 cagtaaaata tctgttgctt ctggataata gcttgcatga tcttttcctg atacatgaat
    73261 gacttcaaaa gacagttcgt tttctttggc tgttctttca cttaaaccgg tggatgcggc
    73321 agtcattcca aacgttcgta taattgctgt tccaataccg ccttgatttc ttcgagaaat
    73381 tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag caagagaaat
    73441 aagtgcatct tttccagtga tttgctgttt tacaacgata gcatccccca ccgcataaat
    73501 atcaggaata ttcgtttgat aacgttcgtc tactaggata cccccgcgta tgcctaattc
    73561 gattccagcg gtcactgcta gctggttatc aggacgaaca ccaatggata aaataactaa
    73621 atcagcaggg atggtacgcc catcatccag tcgcaatcgt ttcccgtggt cttcaaatcc
    73681 agcgacagca tgagaagtaa tcacttctac tccttgatga gacaattctt tttctataaa
    73741 agctgccatt tcttcatcca gtgttggaag aatatgtggt gcttgttcga tcaccatgac
    73801 ttctaaacct cttcttttta ggttttctgc catttccaat ccgatgaatc ctgcaccaac
    73861 gatcacggca cgctttggct gtttttctaa tgcatgcatc actttatcga tatctggtac
    73921 atttctaata gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg gaacaactgg
    73981 ttttgcacca ggagataaaa ccaatgcatc gtactgttca atgtgttttt gaccctcatg
    74041 tacgacttct accgttttgt tttcgggaaa gatggctgtc acttcatgat ttggacgcac
    74101 atctaaacaa aaacgagcgg ataatgattc tggcgtttgg acaagaagat tttcccgttc
    74161 actgatttct cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa catacggtcc
    74221 tttttcaaaa acaacgattt ctgcatcttc cattaatcgg cgaagccgtg tagcagcaga
    74281 cattccacct gctacacctc cgacaataac gattttcatc ttatttccct cctactgttc
    74341 gatcaaacca ttgattcatg ccaccacgta cattcactac atcataacca gatttcttta
    74401 attctttagc tgcttgttta ctcctcatcc ctgattgaca aatcacatag acggtctttt
    74461 ctttgtctcc atcatatctg tttatacttt gtaatggaac atttttagct ccttttatat
    74521 gcccgccccg gtattctgca ggtgttctaa catcaagtaa cgctggattt tccaaaagct
    74581 tttcctttaa ttctgggact gttatcgatt ttattgattg aaatagcaaa ttcattttct
    74641 gcacctcatt tacattttta taaatacctc atggggtata ttaaacagga gctttattaa
    74701 tatgtcaacc agaatgactc ttcatttttt tcactacttt ttatatttgc ataaaatacc
    74761 gataaggggt attatctaat tataaaaata gaggagaatg tgttatggag attgataata
    74821 aaaatatcct gaaccgtttg aaacgtacag agggacaaat tcgtggtatc caaaaaatga
    74881 tcgaagacga aaaagaatgt atggatgtca tcactcaatt aagcgctgtt cgttctagta
    74941 ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa aaattgcttt gagaaacctg
    75001 atagtaatcc agaagaacaa gcggctaaac tagaacaagc gatcaagatg attattaaaa
    75061 agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg atgaattaga aaaatggtca
    75121 gaaacaggga aaaacgtaaa aaacctgata aaagcttctc cagaaacgac gattgtcgta
    75181 tctgtaaatg gcatcgcgat taccggttat ctagactctg ccaatgcaga attcttagat
    75241 ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca tatttcagaa
    75301 agttctttac ctgaacaagt aatcgttgta ccagcaggtg tccttgattt agttgaactg
    75361 caatcccaag gttatgctta tatcaagcct tagtcagtag aggttgcgac agaagtgatc
    75421 agcttcaaga aatttcggct tatttttcga agaagctact tctggaaaac cgtgaatcaa
    75481 aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagcttct
    75541 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttaag
    75601 gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg ggaaaatagc
    75661 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta
    75721 aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg
    75781 gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt tgaataccgt
    75841 ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa
    75901 atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    75961 gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
    76021 acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta ctgggagtct
    76081 atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc tttgaaacat
    76141 ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag tgatgacggc
    76201 aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa ggatcatgcc
    76261 aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta atttgatatt
    76321 tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca agaatagacc
    76381 aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa aaagttgtgt
    76441 caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat tatatctccg
    76501 agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg ctcctgctat
    76561 ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa tacggaatat
    76621 cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta atttcatttt
    76681 atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg gaataaaacc
    76741 aatgatttca ctgtttttat ttttctttac agacactgat attatgagct aatttgagat
    76801 aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg catttctttt
    76861 actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg tttacgtgtt
    76921 ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc ttctgctgaa
    76981 cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa atatacatca
    77041 atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc attgacaaat
    77101 atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct atttgtaact
    77161 gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc caagtaacgc
    77221 tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca caaagcttgg
    77281 ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt cccgatcgaa
    77341 agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga tttctccata
    77401 atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga ttgcgatcgc
    77461 tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa gtaccaacgt
    77521 attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag aaaatgtact
    77581 caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat caaagacagc
    77641 aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca aagtcaataa
    77701 accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga taatcaagcc
    77761 tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta aaaatggatg
    77821 tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc ttccattgat
    77881 ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg tttcgatcaa
    77941 taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca ggacttgata
    78001 ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt tagaaatcac
    78061 agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg ttccatctat
    78121 tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt gaacaatcat
    78181 tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta attttgactg
    78241 gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac gtgacgcgtc
    78301 gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat ttatcaaatc
    78361 aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct tatcaaaaaa
    78421 ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat cggttggctg
    78481 cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca accccataaa
    78541 tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt cttgacgatc
    78601 caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt tgctatagtt
    78661 tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt gactaatcat
    78721 ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat aaataagggc
    78781 ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat ccttattaga
    78841 atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa taaactttgt
    78901 ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca taccccattc
    78961 ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt tgtcaaactt
    79021 tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat aattgctccg
    79081 atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc tttattagct
    79141 attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt gattgcatat
    79201 cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac agcgaatacg
    79261 ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac taatacaaat
    79321 gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg acctgttgca
    79381 aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa ataagaaagc
    79441 caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa aggaacgaca
    79501 agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg attcaaatga
    79561 gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc ccaaccaaat
    79621 gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac agccgcacac
    79681 acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat gatttgagtc
    79741 atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc tgcaatcaat
    79801 gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa atatccagca
    79861 attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa caacagatga
    79921 tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc taaaccataa
    79981 cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc ttttgctaat
    80041 tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc atcttcttcc
    80101 tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc taatttagtt
    80161 ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt cgtctctatt
    80221 ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc catcttacgg
    80281 taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct ttctaaagaa
    80341 ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa atggttcaac
    80401 acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac tgtatcgaca
    80461 actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta atcagaacca
    80521 gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc attcaatgtg
    80581 atatttgctt ctggatagcg atgattgatc acatccaata gataatctac atcttcttgt
    80641 gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc aaagtaagtc
    80701 ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt atcgaagtat
    80761 gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc tttagttgga
    80821 cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc tacccaagga
    80881 ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt cagcaggtca
    80941 cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc tttcatttta
    81001 cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac taaacgggca
    81061 tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt tttcaaaaac
    81121 ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt ggttcctgtc
    81181 acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat attgaaggtt
    81241 gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg gatgtgtggg
    81301 gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc cacatcaaat
    81361 gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga agtcccttct
    81421 gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga ctggactgcc
    81481 acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc ttgctgcatt
    81541 ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc cttattcaaa
    81601 tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc ggcgctcttc
    81661 ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct cgtctgtatc
    81721 tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg ttgtttccaa
    81781 gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca tcagatattc
    81841 attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag tgtcatcttg
    81901 catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag ctttaatgat
    81961 atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg cctgatccca
    82021 ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt cgcttgtaga
    82081 gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc catctctcag
    82141 ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt aaacctttcc
    82201 atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg gtttttcacc
    82261 ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc ctggttcgaa
    82321 tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa ttggtgcttc
    82381 gcttccataa aaatgataac cttgcgtata accataaact tctgagttag aagtgacttt
    82441 tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc aatctagctg
    82501 atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat gtgcttgtcc
    82561 atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt cgcctttttc
    82621 agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg ttgctgagaa
    82681 ataggcatcg atcactaacc ctgttttttc gtggaaaaat tcttgatagc cttcattttt
    82741 taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat gatagattgg
    82801 acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta tgccaatccc
    82861 agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa ctgactgtac
    82921 agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga aatattgcgt
    82981 gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa ttgctcgtga
    83041 gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg tgattccctc
    83101 cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta aaaaaagaaa
    83161 ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga agctattttt
    83221 taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa taatgtcgta
    83281 aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct ggcaaaatgt
    83341 gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac cgccgattcc
    83401 cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca gactttctaa
    83461 atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa gaacattggc
    83521 atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg gcaattgctg
    83581 caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga gcattttctg
    83641 ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa agaaaaacca
    83701 ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga ttttcaaacg
    83761 acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa cagcggttgg
    83821 taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta ctatcgaaaa
    83881 agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg ctgctgttcg
    83941 actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg actgatagag
    84001 taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc tttttttcgt
    84061 aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg tttctaatac
    84121 acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa aaagcggtcg
    84181 ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct gtagctcttc
    84241 tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct ggttcaattc
    84301 tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta atcgaacgat
    84361 ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc tttcctgcaa
    84421 taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca gcgcctgata
    84481 ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt caatatcttc
    84541 caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac cattgataga
    84601 ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact gctcttttct
    84661 ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac accatatctg
    84721 gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca aacgtccatc
    84781 cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt ttgctttgga
    84841 gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta actttgcttt
    84901 gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg ggataaaaaa
    84961 tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac tgattgccga
    85021 ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg ctgacatttc
    85081 gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt gttggacgaa
    85141 aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt tgcaagtagt
    85201 catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac atctgattgt
    85261 cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt ttttccgtct
    85321 ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa aaaagtgaaa
    85381 gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct agataacgaa
    85441 aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat gccaaccctt
    85501 cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt gcattcatga
    85561 tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata agcgttgatt
    85621 ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa cgatcaaaat
    85681 ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt actgtctttt
    85741 ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc caagaaagtt
    85801 gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga atccatccta
    85861 acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg cgaagataaa
    85921 tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc tgcattcctc
    85981 tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat tcataactcg
    86041 ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc ataccgtgtt
    86101 ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca tttctgaaga
    86161 gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg tacctctgtc
    86221 caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg taatagttag
    86281 aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc gcctaattga
    86341 tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac cacttctgaa
    86401 aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc tgctaagaat
    86461 ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc agtcactgta
    86521 cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc tacaacaccg
    86581 tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac tttcccaaga
    86641 tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata aaccgctgca
    86701 taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg atttctgaaa
    86761 tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact ttgcggttct
    86821 aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt ttttactaat
    86881 acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc gatcttttcg
    86941 tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc tttctataaa
    87001 aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc aaataaagct
    87061 ctttatatgc tttttcaaaa ggtttcgtta caaattcatc ctcacggttt tccaataatt
    87121 tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt tctgcatatt
    87181 tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact aaagggatct
    87241 ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat ttatcagaac
    87301 gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt gactcacgta
    87361 atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca tattcttctg
    87421 gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc gctgagaaaa
    87481 ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg ccccattgat
    87541 cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta tttgctccat
    87601 gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg ccaaatgctt
    87661 ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca tcaggacgtt
    87721 ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct cgacttgtca
    87781 ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg attgctttcg
    87841 ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca cctggccagc
    87901 cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga cctttagaac
    87961 gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag ctgagttgtg
    88021 tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt aaagtaattg
    88081 attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa cctatcgaga
    88141 atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct taaaaaattt
    88201 tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc tttacttgct
    88261 tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc atcgacttcc
    88321 ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc ttcgctaact
    88381 gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt tgatggggcg
    88441 gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt taatatcaat
    88501 aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc agctaattta
    88561 ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa cgctttttca
    88621 attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga tttttatttt
    88681 ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa aaagaagtag
    88741 ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca ccgtgaatca
    88801 gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga aaatggcttt
    88861 ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac accgtttata
    88921 tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    88981 tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt acaccgttta
    89041 ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt caaaaaacag
    89101 cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga gaatactgtt
    89161 tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt ccttttatta
    89221 taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt ttttctttaa
    89281 ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc cataacgttt
    89341 tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg tataaccaaa
    89401 taaatctact ccatctttga tagcttcctt catctgctca atatgctgct tcaaatagtc
    89461 aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag ctccgagtcc
    89521 gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca aagcaattct
    89581 caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg gatttttaat
    89641 tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag cactgactgc
    89701 actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta agatttcttc
    89761 atcacctact tctattttta agttgacacc tttttcttca aacattcgtt gcgtatacgc
    89821 tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt gctgctcaat
    89881 tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat agctgatcat
    89941 acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta aagcacttgc
    90001 tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat ggttttcttc
    90061 aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat tgaaagtcat
    90121 ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac gaacgtaaaa
    90181 ctgaataagc tttcgattag gccatccacc atattctgta accaaatata acggcatttc
    90241 ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt caaacacttg
    90301 atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag gaaaaattct
    90361 tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata aacggatgtc
    90421 ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat acttgctgtt
    90481 gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat ctgtccattt
    90541 ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc ctttttcatc
    90601 tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata aaaatccttc
    90661 tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg attatttttc
    90721 ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac cattgtggtc
    90781 ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa atcgccttta
    90841 cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa attcactgta
    90901 tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc aattgcatgt
    90961 ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt tccgtccgtt
    91021 ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc gtttacttca
    91081 gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt tgaggattct
    91141 tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact gatcatcgct
    91201 aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg gaaagacaaa
    91261 atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac tccaccaaat
    91321 atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt cacaccataa
    91381 acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga taaacttttt
    91441 actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg cgcagctacg
    91501 gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt gttggtcatt
    91561 actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa tccgccgata
    91621 acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc tgcaatcagc
    91681 tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac catcacgatg
    91741 atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt gcgaatctta
    91801 ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt acttgtatac
    91861 cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact atatgcactg
    91921 acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg atctgtattg
    91981 aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa tgcatcagct
    92041 gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa actcgtacat
    92101 aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt cggggcaaaa
    92161 acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt tcctctcttt
    92221 ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata cacttcattt
    92281 actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt gatcacacct
    92341 tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt aaagcgtaac
    92401 cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa tcggacaata
    92461 tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa tgccgtagca
    92521 atccttctta caagataagt atagttctta gaaaacggtt tctccattca attagtaccc
    92581 cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc gagcaaatca
    92641 ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga gacaaaaaaa
    92701 acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata ctctgtgatt
    92761 tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt taacggaagc
    92821 ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt tttatggatt
    92881 tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt tttttcttca
    92941 actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa ctcatctaga
    93001 acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc agtagtcaaa
    93061 attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac tggttctatc
    93121 cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag tgtattcaaa
    93181 atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa aggattcaac
    93241 gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg taattgaaaa
    93301 tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga gatgatcttt
    93361 tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat ttgtttgata
    93421 tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc taaaaaacga
    93481 ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt ttcatcatta
    93541 atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc ttgattggaa
    93601 aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat cggaataaat
    93661 aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt caaaacgaga
    93721 taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga tataagaacc
    93781 tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact gatttgttga
    93841 ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa aattcttttt
    93901 gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag ttctaattta
    93961 ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc tgtttttgaa
    94021 agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa caataagtac
    94081 gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt cgtcacctct
    94141 tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc tgaacgttta
    94201 tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat ttcagtttgg
    94261 atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat ccaatgattc
    94321 ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat ttgcttacac
    94381 ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc acttgcagag
    94441 gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag actggataat
    94501 ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc tcccatcatt
    94561 ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc ctgccgatac
    94621 gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt ttattgcctc
    94681 agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt ggattcgatt
    94741 caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata atggtaattc
    94801 ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa ttggccaact
    94861 ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg ctccgccagt
    94921 atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac taaatgcaat
    94981 ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta ctggtgcaca
    95041 gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc acatgacatc
    95101 ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct ctggatcaca
    95161 gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct tagcatttgg
    95221 atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat gatgacaggc
    95281 ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc tagcagggaa
    95341 tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct cattaaaggt
    95401 catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat aaaattcaaa
    95461 aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg ctaagggggt
    95521 ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg tattgattag
    95581 tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc ttggaaatat
    95641 tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca gtaaacgaat
    95701 atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat ggagtgattc
    95761 gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag gatgctggtt
    95821 catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca accatgcacc
    95881 ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa atatttcctg
    95941 atccataact atctctcctc gctatcaaca atttcttact tgaagtatag ctcgattcat
    96001 caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa tgctactctt
    96061 catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa aacactcgtt
    96121 aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa ggtcgtaaat
    96181 caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc cttaaagctt
    96241 cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg agccattgct
    96301 ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc actaattcat
    96361 agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc ttgtacatat
    96421 aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta taatttggat
    96481 tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg ttccattgca
    96541 taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt tcctcttttg
    96601 taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct tttgcttccg
    96661 cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag atataagggg
    96721 tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt cgatacacat
    96781 cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa aataaactat
    96841 tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc agttcagaga
    96901 tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat cctatgtgtt
    96961 cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt ttagcgattt
    97021 cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca aaagttgctt
    97081 gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt tctttatccg
    97141 gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct ttatcgatcc
    97201 agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa ttcaaatcag
    97261 gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc aactgccaag
    97321 cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc ggatcacgcc
    97381 aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg aaccacggat
    97441 gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt cttttctttg
    97501 cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg attgcttgat
    97561 aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga gaaagccaaa
    97621 ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc cgcaaatctc
    97681 caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa acaactgaat
    97741 ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct attttttgct
    97801 taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata gctattgcac
    97861 cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct caactgtttt
    97921 ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt ataaacggtg
    97981 ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga aactattttt
    98041 tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt tatttcacat
    98101 tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt ggagatactt
    98161 cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct aatgcaatcc
    98221 catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa gggatcgcaa
    98281 tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact cctaccataa
    98341 tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa aagaacaagc
    98401 ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct ccaacggcga
    98461 taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag gaacccgcaa
    98521 gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg ttgtctttca
    98581 tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag aaagtcacaa
    98641 gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct acatgtttta
    98701 atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca gaaggcattg
    98761 gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg aagatgccac
    98821 ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc gtcaaccaag
    98881 tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa acgatgatcc
    98941 caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa atcgcatatt
    99001 tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt gtgatcaaaa
    99061 taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga atccccattc
    99121 ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc gttccaattg
    99181 gataacgggc taataccccc attaaaacac agccgatcgc actggctaat gcagtcgcag
    99241 taaacactgc tccttcatcc attccagaag cacctaatac agttggattt acaaataaga
    99301 tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt accgtggtgt
    99361 tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat ccccctaaat
    99421 ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca acgtgtttta
    99481 tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca aaatccgaac
    99541 gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt ggattacaag
    99601 aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca atagtgtgat
    99661 ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc gacaggattc
    99721 agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt tgtcttcttt
    99781 tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg ccgatacttc
    99841 aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta ttcaatcaga
    99901 cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat tgaaagtcaa
    99961 gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga tagtttcaaa
   100021 ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg aaaacttctg
   100081 cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga gtacaatact
   100141 cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt tttctacaaa
   100201 gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt tttgtatcat
   100261 catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt ccattatatc
   100321 acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca atagtttcta
   100381 ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa tgccgctctt
   100441 cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg tgtgtctaac
   100501 actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg cctgtgcgcc
   100561 acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt gtgtttcttc
   100621 cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg ctccttgttc
   100681 atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac ctaaaggcag
   100741 gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct tttcgatatc
   100801 ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat ctacaagcgg
   100861 attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt caatagaaga
   100921 acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag caatgacttc
   100981 gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg cctcattcaa
   101041 taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac catttacgga
   101101 taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca ctattacttt
   101161 tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata gtctgtttgg
   101221 ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt tttacgataa
   101281 aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt tttttgcttt
   101341 tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg atgtttaaat
   101401 ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc ctcagattga
   101461 ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact cactaggaaa
   101521 aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata agcttgtgtc
   101581 aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt aaatgtttcg
   101641 atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat ttcgtattta
   101701 ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa attccaatct
   101761 tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc ttcttcgtca
   101821 gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat gaaaggatag
   101881 atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc tttatcttcc
   101941 aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt cgttgtacga
   102001 tctactttga tcatttctgc tagtttttct tggatgattc caggattttc gcaaatacgt
   102061 actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat attgctaata
   102121 gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat ttcatcccac
   102181 ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac tattttcaat
   102241 aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc ttttacgaaa
   102301 aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt ttcttcgttg
   102361 ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg ttggaagttt
   102421 cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa acaagtttat
   102481 aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact gctcgcaact
   102541 gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca ttttcttcag
   102601 gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc cgtttatctt
   102661 cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact tttggtgttg
   102721 gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct tttcctattt
   102781 cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta tcaaatacat
   102841 cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat tgagccaact
   102901 tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat caagtataga
   102961 agactggttt aattacggca aataaatata atgaaatctg caataaataa aagaatgtta
   103021 aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat ggcgttcaaa
   103081 agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct attcttgtct
   103141 ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact aaacggtgtt
   103201 ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa gctgtttttt
   103261 tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc ggtaaacagc
   103321 gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt cattgatttc
   103381 tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg ttacatcaaa
   103441 ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga tctttttgaa
   103501 tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt caccatagtg
   103561 ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt tgtaccgacg
   103621 ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat atccgtatct
   103681 atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact cggacacaat
   103741 cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag gataaacttt
   103801 cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt ctgcatagta
   103861 ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc gtagtttatt
   103921 cataagatat gtttttcctg taccaggact accagccaga agaatgaaat actttttcat
   103981 ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca atcttatgct
   104041 tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga gacttgttga
   104101 tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa agctccgttc
   104161 caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct tctttcacac
   104221 ctgttcctcc atggataact agggggacat caactactgc atcgatttct ttcagcaagg
   104281 gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata gcaatagcta
   104341 atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt gtatatacct
   104401 tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca agttctcctt
   104461 ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc aggatatttt
   104521 ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg tcgattgctt
   104581 ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca accatttctt
   104641 cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat ttagcggtat
   104701 cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct agcatagcag
   104761 gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac tcttctgctg
   104821 tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc tttttatttg
   104881 tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt gcccatgtag
   104941 taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg gttatagagg
   105001 ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact cttttctaaa
   105061 tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac ttgttcataa
   105121 agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa ttgtgtaatc
   105181 tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt tgccagaact
   105241 tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc tactttcaat
   105301 taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc ggctactgta
   105361 tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt tactagcaaa
   105421 gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc tcctcggcgt
   105481 ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt ggttagcata
   105541 ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat aatcgtacca
   105601 atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa gaaaactgga
   105661 caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg aaatgccggc
   105721 acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc cactacgaat
   105781 tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa ttcagaagcg
   105841 aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac gaccatgaca
   105901 gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc ttcgatcgac
   105961 tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa taagtacccg
   106021 atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg aatgatcggt
   106081 tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc gaccaagatc
   106141 aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt tgccatccat
   106201 aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc caaaataata
   106261 ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc caaatcattc
   106321 attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg aaatccttca
   106381 gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc ggcactcaac
   106441 acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc tgatttcttc
   106501 tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg agtcaaaata
   106561 ttttcgatga taaaattgat aacgcccatg tt
//
LOCUS       DACCVH010000003        77334 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.003, whole genome shotgun sequence.
ACCESSION   DACCVH010000003 DACCVH010000000
VERSION     DACCVH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.003"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..830)
                     /locus_tag="IVV98_000241"
     CDS             complement(<1..830)
                     /locus_tag="IVV98_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HAP7805929.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
     gene            complement(901..1451)
                     /locus_tag="IVV98_000242"
                     /pseudo
     CDS             complement(901..1451)
                     /locus_tag="IVV98_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            complement(1654..2133)
                     /gene="rlmH"
                     /locus_tag="IVV98_000243"
     CDS             complement(1654..2133)
                     /gene="rlmH"
                     /locus_tag="IVV98_000243"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP7805930.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            2561..3850
                     /locus_tag="IVV98_000244"
     CDS             2561..3850
                     /locus_tag="IVV98_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP7805931.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(3889..4494)
                     /locus_tag="IVV98_000245"
     CDS             complement(3889..4494)
                     /locus_tag="IVV98_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP7805932.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(4699..5163)
                     /locus_tag="IVV98_000246"
     CDS             complement(4699..5163)
                     /locus_tag="IVV98_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7805933.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(5185..5505)
                     /locus_tag="IVV98_000247"
     CDS             complement(5185..5505)
                     /locus_tag="IVV98_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP7805934.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(5649..6728)
                     /gene="pepA"
                     /locus_tag="IVV98_000248"
     CDS             complement(5649..6728)
                     /gene="pepA"
                     /locus_tag="IVV98_000248"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP7805935.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            6928..7278
                     /locus_tag="IVV98_000249"
     CDS             6928..7278
                     /locus_tag="IVV98_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7805936.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            7501..8448
                     /locus_tag="IVV98_000250"
     CDS             7501..8448
                     /locus_tag="IVV98_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7805937.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(8505..9923)
                     /gene="pepV"
                     /locus_tag="IVV98_000251"
     CDS             complement(8505..9923)
                     /gene="pepV"
                     /locus_tag="IVV98_000251"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP7805938.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            10072..10917
                     /locus_tag="IVV98_000252"
     CDS             10072..10917
                     /locus_tag="IVV98_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP7805939.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            10921..11361
                     /locus_tag="IVV98_000253"
     CDS             10921..11361
                     /locus_tag="IVV98_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP7805940.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            11411..11605
                     /locus_tag="IVV98_000254"
     CDS             11411..11605
                     /locus_tag="IVV98_000254"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805941.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            11741..12418
                     /locus_tag="IVV98_000255"
     CDS             11741..12418
                     /locus_tag="IVV98_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7805942.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(12826..13515)
                     /locus_tag="IVV98_000256"
     CDS             complement(12826..13515)
                     /locus_tag="IVV98_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805943.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13490..15619)
                     /locus_tag="IVV98_000257"
     CDS             complement(13490..15619)
                     /locus_tag="IVV98_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP7805944.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(15667..17004)
                     /locus_tag="IVV98_000258"
     CDS             complement(15667..17004)
                     /locus_tag="IVV98_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP7805945.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(17256..17615)
                     /gene="rplT"
                     /locus_tag="IVV98_000259"
     CDS             complement(17256..17615)
                     /gene="rplT"
                     /locus_tag="IVV98_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP7805946.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(17668..17868)
                     /gene="rpmI"
                     /locus_tag="IVV98_000260"
     CDS             complement(17668..17868)
                     /gene="rpmI"
                     /locus_tag="IVV98_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP7805947.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(17940..18464)
                     /gene="infC"
                     /locus_tag="IVV98_000261"
     CDS             complement(17940..18464)
                     /gene="infC"
                     /locus_tag="IVV98_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP7805948.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            18784..19416
                     /locus_tag="IVV98_000262"
     CDS             18784..19416
                     /locus_tag="IVV98_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP7805949.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(19418..20323)
                     /locus_tag="IVV98_000263"
     CDS             complement(19418..20323)
                     /locus_tag="IVV98_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP7805950.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(20408..21061)
                     /locus_tag="IVV98_000264"
     CDS             complement(20408..21061)
                     /locus_tag="IVV98_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7805951.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            21383..22327
                     /gene="mvk"
                     /locus_tag="IVV98_000265"
     CDS             21383..22327
                     /gene="mvk"
                     /locus_tag="IVV98_000265"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP7805952.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            22320..23297
                     /gene="mvaD"
                     /locus_tag="IVV98_000266"
     CDS             22320..23297
                     /gene="mvaD"
                     /locus_tag="IVV98_000266"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP7805953.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            23310..24395
                     /locus_tag="IVV98_000267"
     CDS             23310..24395
                     /locus_tag="IVV98_000267"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP7805954.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            24392..25456
                     /locus_tag="IVV98_000268"
     CDS             24392..25456
                     /locus_tag="IVV98_000268"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP7805955.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(25705..26508)
                     /locus_tag="IVV98_000269"
     CDS             complement(25705..26508)
                     /locus_tag="IVV98_000269"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP7805956.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(26528..27370)
                     /gene="kduI"
                     /locus_tag="IVV98_000270"
     CDS             complement(26528..27370)
                     /gene="kduI"
                     /locus_tag="IVV98_000270"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAP7805957.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(27386..28393)
                     /locus_tag="IVV98_000271"
     CDS             complement(27386..28393)
                     /locus_tag="IVV98_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP7805958.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(28400..29044)
                     /locus_tag="IVV98_000272"
     CDS             complement(28400..29044)
                     /locus_tag="IVV98_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP7805959.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(29144..29902)
                     /locus_tag="IVV98_000273"
     CDS             complement(29144..29902)
                     /locus_tag="IVV98_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP7805960.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(30029..31180)
                     /gene="fucO"
                     /locus_tag="IVV98_000274"
     CDS             complement(30029..31180)
                     /gene="fucO"
                     /locus_tag="IVV98_000274"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAP7805961.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(31262..31573)
                     /gene="rhaM"
                     /locus_tag="IVV98_000275"
     CDS             complement(31262..31573)
                     /gene="rhaM"
                     /locus_tag="IVV98_000275"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAP7805962.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(31575..32420)
                     /gene="rhaD"
                     /locus_tag="IVV98_000276"
     CDS             complement(31575..32420)
                     /gene="rhaD"
                     /locus_tag="IVV98_000276"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAP7805963.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(32434..33690)
                     /gene="rhaA"
                     /locus_tag="IVV98_000277"
     CDS             complement(32434..33690)
                     /gene="rhaA"
                     /locus_tag="IVV98_000277"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAP7805964.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(33687..35147)
                     /gene="rhaB"
                     /locus_tag="IVV98_000278"
     CDS             complement(33687..35147)
                     /gene="rhaB"
                     /locus_tag="IVV98_000278"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAP7805965.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            35300..36169
                     /locus_tag="IVV98_000279"
     CDS             35300..36169
                     /locus_tag="IVV98_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7805966.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(36295..37194)
                     /locus_tag="IVV98_000280"
     CDS             complement(36295..37194)
                     /locus_tag="IVV98_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7805967.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(37359..38183)
                     /locus_tag="IVV98_000281"
     CDS             complement(37359..38183)
                     /locus_tag="IVV98_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7805968.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(38194..39489)
                     /locus_tag="IVV98_000282"
     CDS             complement(38194..39489)
                     /locus_tag="IVV98_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAP7805969.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(39505..39984)
                     /locus_tag="IVV98_000283"
     CDS             complement(39505..39984)
                     /locus_tag="IVV98_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP7805970.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(39990..41018)
                     /locus_tag="IVV98_000284"
     CDS             complement(39990..41018)
                     /locus_tag="IVV98_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAP7805971.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(41035..42141)
                     /locus_tag="IVV98_000285"
     CDS             complement(41035..42141)
                     /locus_tag="IVV98_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP7805972.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(42370..44967)
                     /gene="adhE"
                     /locus_tag="IVV98_000286"
                     /gene_synonym="adhC"
     CDS             complement(42370..44967)
                     /gene="adhE"
                     /locus_tag="IVV98_000286"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP7805973.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(45272..45652)
                     /gene="yajC"
                     /locus_tag="IVV98_000287"
     CDS             complement(45272..45652)
                     /gene="yajC"
                     /locus_tag="IVV98_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP7805974.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(45749..46894)
                     /gene="tgt"
                     /locus_tag="IVV98_000288"
     CDS             complement(45749..46894)
                     /gene="tgt"
                     /locus_tag="IVV98_000288"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP7805975.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            47112..47810
                     /locus_tag="IVV98_000289"
     CDS             47112..47810
                     /locus_tag="IVV98_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP7805976.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(47978..50617)
                     /locus_tag="IVV98_000290"
     CDS             complement(47978..50617)
                     /locus_tag="IVV98_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7805977.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(51236..52267)
                     /gene="queA"
                     /locus_tag="IVV98_000291"
     CDS             complement(51236..52267)
                     /gene="queA"
                     /locus_tag="IVV98_000291"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP7805978.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            52460..53635
                     /locus_tag="IVV98_000292"
     CDS             52460..53635
                     /locus_tag="IVV98_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7805979.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            53639..54280
                     /locus_tag="IVV98_000293"
     CDS             53639..54280
                     /locus_tag="IVV98_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7805980.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            54277..55194
                     /locus_tag="IVV98_000294"
     CDS             54277..55194
                     /locus_tag="IVV98_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7805981.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            55191..55862
                     /locus_tag="IVV98_000295"
     CDS             55191..55862
                     /locus_tag="IVV98_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7805982.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(56403..56891)
                     /locus_tag="IVV98_000296"
     CDS             complement(56403..56891)
                     /locus_tag="IVV98_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP7805983.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(57092..57358)
                     /locus_tag="IVV98_000297"
     CDS             complement(57092..57358)
                     /locus_tag="IVV98_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP7805984.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(57358..57621)
                     /locus_tag="IVV98_000298"
     CDS             complement(57358..57621)
                     /locus_tag="IVV98_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7805985.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(57614..57886)
                     /locus_tag="IVV98_000299"
     CDS             complement(57614..57886)
                     /locus_tag="IVV98_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7805986.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            58097..58282
                     /locus_tag="IVV98_000300"
     CDS             58097..58282
                     /locus_tag="IVV98_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7805987.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(58424..60247)
                     /locus_tag="IVV98_000301"
     CDS             complement(58424..60247)
                     /locus_tag="IVV98_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP7805988.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(60845..63550)
                     /locus_tag="IVV98_000302"
     CDS             complement(60845..63550)
                     /locus_tag="IVV98_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP7805989.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(63856..64803)
                     /locus_tag="IVV98_000303"
     CDS             complement(63856..64803)
                     /locus_tag="IVV98_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP7805990.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            64993..65262
                     /gene="rpsN"
                     /locus_tag="IVV98_000304"
     CDS             64993..65262
                     /gene="rpsN"
                     /locus_tag="IVV98_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP7805991.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(65438..65800)
                     /locus_tag="IVV98_000305"
     CDS             complement(65438..65800)
                     /locus_tag="IVV98_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7805992.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(65811..66932)
                     /locus_tag="IVV98_000306"
     CDS             complement(65811..66932)
                     /locus_tag="IVV98_000306"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP7805993.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(66948..67298)
                     /locus_tag="IVV98_000307"
     CDS             complement(66948..67298)
                     /locus_tag="IVV98_000307"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP7805994.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(67428..68939)
                     /locus_tag="IVV98_000308"
     CDS             complement(67428..68939)
                     /locus_tag="IVV98_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7805995.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(69261..70613)
                     /locus_tag="IVV98_000309"
     CDS             complement(69261..70613)
                     /locus_tag="IVV98_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP7805996.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(70766..71842)
                     /locus_tag="IVV98_000310"
     CDS             complement(70766..71842)
                     /locus_tag="IVV98_000310"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP7805997.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            72038..73783
                     /locus_tag="IVV98_000311"
     CDS             72038..73783
                     /locus_tag="IVV98_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP7805998.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(74063..74500)
                     /locus_tag="IVV98_000312"
     CDS             complement(74063..74500)
                     /locus_tag="IVV98_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP7805999.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(74484..75857)
                     /locus_tag="IVV98_000313"
     CDS             complement(74484..75857)
                     /locus_tag="IVV98_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806000.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(76179..76667)
                     /locus_tag="IVV98_000314"
     CDS             complement(76179..76667)
                     /locus_tag="IVV98_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806001.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(76689..77291)
                     /locus_tag="IVV98_000315"
     CDS             complement(76689..77291)
                     /locus_tag="IVV98_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7806002.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        22220 a        16482 c        14093 g        24539 t
ORIGIN      
        1 taaactaatt tgaaatcgct acagatttct tgtcgatcac taacacgaac cttatgagcg
       61 atatttctag atatatggac acaacattgt tgaaattgag catttggata aacactatga
      121 atactatcgt caataccact taaaccatct gttacgacta acaaaacctc ttctaaacca
      181 cggtctttta gatcttgaag aatctctttc caaacataag cagattcagt tggagctata
      241 gtaaatccta gaacctcttt agttccatcc aacctgatac caattactat atagacagct
      301 tcttttgata cggtttgtct ttttaaggga atatgagtag catccataaa aatgactgag
      361 tatttagctt ctaaagttct ttctttaaat gccgaaacat cttcagacac aattttactc
      421 atatttgaaa tagtttgtgg tttgtaataa tgaccataca ttttttcgat tagatcagag
      481 atttcggaca tagtaattcc tttttgaact agctgaataa tagtggtttc taaagagtca
      541 ttggttcttt tataagcagg taaagtttgt tgagaaaagt ctccattcct atctctaggt
      601 attactaaat tcaattcacc gtactctgtt ttaaaagagc gcgaataatt cccattacgg
      661 gaattacctg aattaaatcc agctctatca tacttttcat agtcaagaaa taccgttaat
      721 tcagcttgta ataaagcgtt aatagccaat tctaggtgac gacgaaacaa atcatccaaa
      781 tcacctttat tgattagtat ttccataatt tctgtagtaa aatcgttcat atggaagtcc
      841 tcttttctgt gaatgtgttg tggtaactct attctacaga agggacttcc ttttttctat
      901 ttacacaaaa tattttacac tctcttcaac gatattcttg taagtaatta tgccccaact
      961 aggatttgtg ggttcatttc catctggagt taaaaaaaca aaaatttttt tatagttaga
     1021 ataattgcgt tctatatata tttggtattt attaagttgc cctccagact ccgaagacag
     1081 aattttattt tcgatgcaca ccactatttt atttttttcc gataccaata aaatatcaat
     1141 attcttattt tctctgtaaa caattaaatc ttcatagcta ttaagtaaag catcaaaata
     1201 attgatagca gctttggtat catcattaga atctatatac cttttcaaaa acattttaaa
     1261 aaactcatca gataaattgt gggtttcatt tggagcaaac aaaaaagcta aaaaattact
     1321 atgtcttatt tcatttttag atagcttaag tatctgaaat atatttgttt tcccagtcca
     1381 tttagatagt tttcttcaat atcatccata tcctctaata gattttttaa acactttttt
     1441 tcatctatca tgttttttct ccttgccatt attctaacta aaattttacg tatttgtttc
     1501 tatgtctaca ttatcttttt aacagtatct atttttcttt tgcaacttac ttggctacca
     1561 aagcaaataa aaaagttatt tataaatttc tccctaccac tacctattgc tattatttaa
     1621 aatagggata attttttctc ttaaaaaata tcattatttg tggtatggag cccccgcatt
     1681 gatccggaag gcacggtaga tttgctcgac aaggatcaga cgcatcaatt gatgtggata
     1741 cgtcattttt ccaaaagaga tctgagcatt gcttcttttc atgacggctt cgctgagtcc
     1801 taaagagccg ccgataacaa aaacaaggtg gctttttcct tggataccta attggtcgat
     1861 ttgtttagca aaagattcac ttgtaggatt tttcccttca attgctaagg catagacgta
     1921 ttcttgttct ttgattttcg ctaagatccg ttccccttct ttttctttta cttgtctcat
     1981 ttgcgcttcg cttaaattct ccggggcttt ttcgtcagga acttcgatca attcgatttt
     2041 tgcataggca ttcagccgtt tgacatactc attgatacct tggatcaggt atttttcttt
     2101 taattttcct actgagataa ttttgatatt catgttttct ctcctttggt cttcatgctc
     2161 actttgttta ttataatcaa ttttttcgtc tatatgttta ttttggctat ttttgttaaa
     2221 aagatttccc caacagttat gcacaacatc cacaggttta tccacagaaa acagtgttat
     2281 tttaccttat ttcatcacat tcattaggca aacatacgtt ttataagaat ttatccactt
     2341 tatacacagg ctgtggatat gttttatccc ttatttttcc aatcctatcc gcgtagtttt
     2401 acacagtatc tgtggaaaaa gaaaatcaaa tattttcatc tgaaaacaat gatttttcct
     2461 aaagtttttc ataaaaagtt cacagtctca aagtagacta aagtcaacaa ataagactat
     2521 actaacagta gataaatgaa tgtaattgga ggaggaacac atggatagaa aaaatgtgac
     2581 accaaagatg aaaaaaagta aaaataatag cctctggcgt aagttaggtc tggggcttgt
     2641 tggagggatc gttggaggac tactgacagc tggcattttt tatgcagcga tgggcactgg
     2701 caacaatagt tctactgcta caagcggcaa tcagaattct gccggtgaaa cagttgtgga
     2761 aaatgtcaaa gtcaatgtag attctgatat caccaaagcg gtagataaag ttcaagacgc
     2821 tgtcgtttct gttatcaact tacaaagtca aaaccaatca agcggttttg gcggactatt
     2881 cgggcagcaa gaagaaagta gcagctcaga tgatagtaat ttggaagctt atagtgaagg
     2941 aagcggcgtg atctacaaaa aagacgggaa tactgcttat gtagtcacga ataatcacgt
     3001 agtagatggc cagcaaggtc ttgaagtctt gatgaaagac ggtacgaagg taaaagctga
     3061 attagttgga acagatgctt attcagattt agcggtgttg aagatcaatt cagacaaagt
     3121 cgaaacagtt gcctcttttg gtgactcaag tgctctgaag gttggtgagc ctgcgattgc
     3181 gattggttcc ccactaggat ctgaatatgc aaattctgtc acttcaggaa tcatttcttc
     3241 cttgaaccga caagtgacaa gtacgaatga atcgaacgaa acagtcaata tcaatgcgat
     3301 ccaaacagat gcagcaatca accctggaaa ttctggtggt cctttagtta atatcgaagg
     3361 acaagttatc ggtatcaact caagtaagat cgcaagtact tctgaatcta cttctaatgt
     3421 aagcgtagaa ggaatgggat ttgctattcc aagtaacgat gtagtgaata tcatcaatca
     3481 actggaaaaa gacggaaaag tgacacgtcc agctctaggt atcacaatgg tcgacttatc
     3541 tgccgtttct actcagcaac aagaacaaat cttgaagatt ccttcatctg taactaacgg
     3601 tgtcatcgtg acaaatgtcc aaacagctac accggctgaa aaagctggat tgaaacaata
     3661 cgacgtcatt actaagatcg atgacaaaga agtttcttct ggtgtagaac ttcaatctgc
     3721 tttgtataag aaaaaagtgg gagattctgt caaaatcact tactatgaag gctcgaaaga
     3781 aaaaacaact actgttgaat tgacgatcga tcaatcggca ttaaaacaaa atcaaaatag
     3841 tgaaaattaa taaaaaagag gttgtgacaa agacttgtca caacctcttt attttggaaa
     3901 tgcttctccg actacggcat cctcaggcaa tactaagatt cctttttttg ctggagcatt
     3961 tggcaaatgc aattcacgag cggaacagat cattccatag ctatctaccc ctcgcaaagt
     4021 tcctggccag atcatcattc catctggcat catagctcct ggttttgcaa cgacaacttt
     4081 ttgtccagct tcgatattgg gtgcaccgca aacgatttgc aatactgtac cattgtctac
     4141 ttctgtctca gtaatcgata aatggtcaga atcaggatgt gggacgcatg tttttacgta
     4201 cccgacaacg atcttcggtt catgatcagc ttcaagctgt tcttcgaatc ctgcttcttt
     4261 gatcaatcga ttcaatttcg ctaattcctc atctgttaag cttacttggc cgttcccttc
     4321 gattgttaga tgatcggaga tatggaaaaa gttccaagca acaacttgac cttgttcatc
     4381 tttgatccga gcaacattcc atttgcgttc aacagtgttt tctgttcctt tatcgtcggc
     4441 tataataacc atcaaggtgt ctccgacgtg tgctttgtta taagcaaaaa tcatgttctt
     4501 tcctccatta tcctttgctg agatttatct taacaaaaaa ttgcattcac tgcatgaaat
     4561 ttttttcatg ctttatttcc gaagaagcct cttctggaac accatttatt cgtaacaagg
     4621 gactgtgaca agacttttgt cacagtccct ttactgtttt agttaattga ttaaaaaggt
     4681 cgtacaagtt ccacttgctt aattacttgg ctgttcttct tcgtcagaaa cgatcaagac
     4741 atcacaaggt gaatgacgta tcacgtagct ggctacactt cctgtcataa agcgttcgac
     4801 tgcatttaga cctgactgcc caaccatgat tagatcgatc tcatattttt ttggcaattt
     4861 gactgccatg gattcacgaa cagaaccata tgcaataatt ccttctatat ttgtgtaatc
     4921 aacagatttc ccatattctt tacattcttc gatcatttcc ttggctgttt cagtttgctg
     4981 atcgactaga ttttgatcaa taggtgcata gcccataaag ttataaaatt gctgatcgat
     5041 tacgtttgct acatatactt tcccattatt acggcgagcc acttctaccg cttttttgaa
     5101 agcagcaagt gcttgttcac taccgtcgat acctactaaa atattcttat attcttgatt
     5161 catcttgacc cctcctaaca gatgtcagcc ttttgttaca ctttctagga acgattcgat
     5221 ttcctgtttt gttttacgat ctttattcac tagacgacct aattcttttc cgtcttggat
     5281 cacgacaaaa cttgggatac caaaaatgtt ccattcagcg gctacatcta tgtacttgtc
     5341 acggtctact tcaataaatt gccaatcaga aaagtcattt tcaatttcag gcatttgcgg
     5401 tttgataaaa cggcagtctc cgcaccagcc ggcagtaaag aaaaatacac tctttccagt
     5461 ttctacgtag cctgctaatt cttctaaact atttgggata atcattcttt gtcctctact
     5521 ttctgtttat gtatttttca attaaattat acacctttct ttcgaactaa caaacattga
     5581 tcctcttttt ataaaaaaaa tctggcaaaa agcaatcttt tgccagattt tatagtttca
     5641 ctatcgcatt attttccgta tacgatcgta tttactgttg atttatccaa acctttcagt
     5701 gtttgaatca acatttctcg tgcagcttca aaatcgcgaa tactgaacat cgtttgatgc
     5761 gtatggatat aacgtcccac tacgccaatc actgtacttg ggattccttc gttttgtgta
     5821 tgagcagcac ctgcatctgt accgcctttt gaaacaaagt attgataagg gatattgttt
     5881 gtttcagcga tatccagcaa gtactcgcgc aaacgaggaa gcatgatcaa acctggatct
     5941 tggatacgca tcaatgtacc ttctcctaaa tgtccgaatg tgccattttt cgtcactgta
     6001 tcatctgctg cagagcagtc tactgcaaag aacagatctg gcttgaattt attgacagaa
     6061 gctttagaac cacgcaagcc tacttcttcc tggacattcg cgcctgcaat caatgtatga
     6121 cctaatgttt cattttgcaa cgcttctaaa gcttctaata ccattgtaca gccatagcgg
     6181 ttgtcccatg atttactgat aatattcttt ccgttggctg ttttgatcgt ttcagcgtaa
     6241 ggaacgattg tgtctcctgg aaggacaccg taactcattg cctcttctct tgattcaaac
     6301 ccagcatcga acaaaatatc ggttacttct actgattttt gtccgcttgt tcctcgcaat
     6361 aaatgtgggg gaacggaaga agaaatacat ggataattct taccagtaga ggttttaagt
     6421 gtaaaacgct gagcagaaac aacgtaagga ttccagccgc ctagaggtac gactttaaaa
     6481 agcccgtttt cttggatttg tgtcagcatg aatccgactt catccatatg tgctgcgacc
     6541 attacacggg gtgcatccgc ttcttcatga tggcgcagac caaaaatgcc gcccaaacca
     6601 tctaactgta actcatctac cagcggttcc atatgacttt ccatataagc gcgaacatct
     6661 tgttcaaaac cgcttgttcc ttgtaattct gttaactctt tgattcgttg aaatgttttt
     6721 tcttccatat gctattcgtc taaatttcag actaaactcc tctcagactt atattgatct
     6781 gcggataaaa tatgattttt tctgcagacc gatcgtattt attatagctt attttttctg
     6841 gtagcggtta tttatttcaa agaaaatatg agagtgtggt aaaataagca caaggagtaa
     6901 caagtgagaa gaaggaggta tgtccacatg tatgaagaaa gcgaactaag ctattttaaa
     6961 ggcgggttag cagttggaat cggtctagga ttattgagcg gggtagcttc aacgatttgg
     7021 tatcatcgca aaaaagtatt gtcagcagac caagtacttg aaaatatcaa gtcatctttt
     7081 ctaaaagaag gtgcaatcga aggttcttgg atctcttttg aaaaggaacc tattaggaaa
     7141 ttcgccgttc ggtcgagtgc ttatcgggga ggtctttctc gaatagaaga tggcgaaact
     7201 gtttattatg aatttttagc agatgctcat acaggaaccg tattagaaat ttcaagaaaa
     7261 aaaggtgcaa cagattaata cgtcaaaaaa gtgagagaac gaatacgcac ccactattca
     7321 aaagagaggt atcatgtcct tcttttgtag tgggtggttt tttagataga gctttccaaa
     7381 catatattcc agtattttct ttttaaataa atgatattta gcgggaaaaa ctagcatttc
     7441 ctttgattat gaggtatttt taatttagct tttgttttct atagttaagg agagtgaaaa
     7501 atggaacaac aagaaaaaat tgctgttctg attccttgtt acaatgagga agcaacaatt
     7561 tcaacagtca ttgcagactt taaacgagaa ttaccagaag cagatattta tgtctatgat
     7621 aataattcga ccgatcgaac atacgaattg gccgttcaag gtggagcaat cgtaaaaaaa
     7681 gaacctcgtc aaggaaaagg aaatgtgatc cgccaaatgt tctttgatat cgatgccgac
     7741 tattatttaa tggtagatgg cgatgatact tatcctgcag aagctgtaca tggtttgctc
     7801 gagaaattac gttctggtga agcagatatg gtcattggtg atcgcctatc aaatggaacc
     7861 tactttgatg agaataagag acctttccac gattttggaa ataaccttgt tagaaataca
     7921 attactagaa tgtataaaac aaaaattctt gatgtcatga ccggctatcg aggattcaat
     7981 cgtatctttg tcaaaagttt tcctattatg agttctggtt ttcaaatcga aacggaattg
     8041 acgatccatg ctttagataa aaaattcaag ttcgttgaaa tcccaatcga ttatcgtgat
     8101 cgtcctgaag gcagcgaatc aaaattgaat acattctctg acggattcaa agtgatcatg
     8161 atgattatta aaatgtttaa agattataag cctttgcttt tctttgggat ttggaccatc
     8221 ttcttctttt tatttggatt ggtcacgggg attcctgtga ttcgcgaata tatgctgaca
     8281 agctttatta cacgcatccc ttctgcgatt ttaagtactg gattgatgac tttagcactt
     8341 ctttcattag taacagggtt gattttggat acagtcgtca cgaacgctaa gaaagaatat
     8401 gaattgaatc tatatcatgt ttatcatgaa taccacagta gaaagtaaaa aaaggatcaa
     8461 gactgcaaaa ataatttgca attcttgatc ctctttttaa ttaattattt cgccaaacga
     8521 tagatggcat ctgcatagat tgctgttgct ctgaacaagt catcaagact cataaattcg
     8581 tttgcttgat gcattgtatc agtatatcct gggaacatcg ctccataagc aacgccacgt
     8641 ttcaacaaac gtccgtaagt tccgccaccg atgatttgtt cgtagccttt ttctccagtg
     8701 tggtcttcat agacttgcaa taatgtagcc accaatggat catccattgg tacgtaatgt
     8761 ggttccatta cgcgagcacc tcgagtaact gttgcgcctt cttgccccac tgtttgttcg
     8821 atgtcacttt gcaatccgtc tactgttaca ccttttggaa aacggaaatt catattgatg
     8881 aagttcgctt cctctgtacc attttcttca aaagcaaata gtccagcatt cattgtcaat
     8941 ttgcccattt tttcatcttc ataagcgact cctagttttt ctccataaaa atcttcatgg
     9001 acataagcag ctgctacatg gataaattgt ttagcagatc ctaggaattc atagttatct
     9061 aagaacaatg ccaagaaaga acctgcattg ataccagatt gtgggcttgc accatgtgcg
     9121 cctttaccaa ctaattcgat ttttacatac gtattgtccg cttcaatcgt tccgcttact
     9181 ggatttgctt cgatgaattg gtaaaatgct tcttccatcg cgatagctgc atctgcactt
     9241 ggtacttgaa gtgctgcagt tgctgttcct ggcaccatat tttcgcgaag tccggaaaca
     9301 aaagatttca agacataatc tcctgcattg tcgcctttga agcgtaaagc taaagaaaca
     9361 tttccttttt caccattgat gattgggaat tcagcatctg gtgagaaacc aaaatctggt
     9421 tcttcttcat gttcgaaata ataagccata tcgccccagc cgctttcttc atcgctgccg
     9481 actacgaagc gaactttttt tgatagtttc aagtcaagtt ctttaatgat cttcatcgca
     9541 tagtaagctg ccatacttgg acctttgtca tcgcttgatc cgcgtgcaaa gatctttcca
     9601 tccttgatta ctggttcata aggatctgtg tcccagccat ctcctgcagg aacgacatcc
     9661 atgtgtccaa atatccctag cgtttcgtct ccttcgccaa gatcaatatg ccctgcatag
     9721 ttatcgacat tttttacttt aaatccatca cgttcgccat aagctaacat atgtttcaat
     9781 gcgtcgcgag gtccaggtcc aaatggtgca tctggtgtta cttttgagtc atcgcgctcg
     9841 ctgttgacac gtaaaagatt tttcaagtct tcaagcaagt cttctttacg tgcttctact
     9901 tctttttgcc aatcaattgt cataaagtta atcctccact tatttaagtc ttcgtgttca
     9961 tgataccaca aattacagaa aaaaatagtt caaaaaatct gacaattcct tttcttatct
    10021 gtttttctct aaaaaaaata tacgctataa tgagtaaaag gaggttttta gatgctgata
    10081 aacgaacaac tagtgaaaag agtcatcaca cctcgtccaa aaatttcaca taaaggaaca
    10141 tttggacgta tcgttttgat tggcggcaat gaacaatatg gcggagcaat cattatgagt
    10201 gctttagctg ccgtacacag cggagcgggt ctcacgactg tagtaactga tgaaaaaaat
    10261 cggagtgctc ttcacagtca tctgccagaa gcaatgattg tagtttggac ggatactgac
    10321 cagtttcttt ccgtaataaa gcaagcagat gtactcttga ttggtcccgg attgggtact
    10381 tcttctaaga gtttggaacg tttcaaacaa gtactagaaa accaatcaaa agaacaatgg
    10441 ctggtgattg atggctctgc tttaagttta cttgctgcta atcatctttt gctaccctat
    10501 cccgaacaaa ctgtacttac acctcatcaa atggagtggc aacggttgag ttctctaccg
    10561 atacaagaac aacgggataa agaaaacaaa aagaagcaac aggaaatcgg tgctgtgctc
    10621 gttttgaaaa gtcatgagac aaaaatttat ggtcaccagc acttctacac caatccttta
    10681 ggttctgctg ctatggcaac gggcggcatg ggtgacactt tagctgggat gatcacagga
    10741 tttttagccc agtttcctca aaatgaccaa acgattgcag cagctattta tcttcatagt
    10801 ttcattggag accagctggc aaaagaacaa tatattgttt tgccgacaca aatcagcgaa
    10861 gcacttccga aatggatgaa ttatttttgt aaaaaatcaa tggaaaacga ggcatgagtc
    10921 atggagaaat ttacaggtta tgtgcgagaa cctttttatt atgaaacaga tcaaatgggg
    10981 attattcatc acagcaatta tatccgctgg tttgaagagg ctcgggtagc cttattggta
    11041 catctagggt ttccctataa aaaaatcgaa gaatctggga tcatcatccc cgttctggaa
    11101 gtaaattgca gctataaaga aatgatccat tacggagaaa aagtgagcat ccatccaact
    11161 atccaaaagt atacggggac acggttggat tttagctacg aaattgtggg aactgaagac
    11221 aaaaaattaa aaactactgg cagtagtaaa cactgttttt tactttctga ttcgcaacga
    11281 ttagtgaagc tgagcaaagt caatccggag ttagatcagt tattccaagc gtacgcttct
    11341 ttggatgatg taaattctta ataaagaccg tctaagcatt tttcttgtat tgtgtcgagt
    11401 agttcgtata atgaaaagaa aaaagcaggt gatccccatg tatgtcgtta aagtaatgca
    11461 cggttacatc gataaaactg gctgtcgcac tcgggaaaaa aacttagaca atctgctcat
    11521 tttcaaagac aaaaaagaat ccgaagcttt tgctaaaaga atcggcggtc gtgtcaaacc
    11581 gatccaagag gtacgaccag attgattcaa tatttttctt ttcgaggctc taataggcat
    11641 gcctatcagg gctttttttg cagactgtgt ttttatgccc acacgatttg taagcgattt
    11701 atgttataat agattatatc tgcatagaaa ggaaggttaa atggttatca ataatttgca
    11761 acagcaagct tatgaatcta tacgtaaaca aatcatttat tccgagttag cacctggaag
    11821 taaaatctcc gataaagtgt tagaagaaca actagctatc gggcgtacac cgattcgaga
    11881 agcactgatc caactgcgca atcaagagct tgtaaaaacc attccacagt ccggcactta
    11941 tgtttcaaaa atcgatatcc gatctgcttc attagcccgt tatacgcggg aaaagttgga
    12001 aaaaccgatc ctgcaagaat gcagtgcgaa aatgaccaag caagatcaag ctaaactaga
    12061 aaaaatacta gaacaaaccg atcaggcagt aatcgctcaa aataaaaaag ctttttttga
    12121 tttggatact gattttcacc gaacttgtta tgaaattgct ggaaaacgag aaatttggga
    12181 ttggctagaa agttatagta cgcgtttcag atggttacgt ttgacgattt cagaattaga
    12241 ctggggtcga gtattagatg aacatcagac aatgcttcaa tcaatgattg atcataactt
    12301 tgatgaagtc ggatttcttt gcacgatgca tttacatatg attatcgagg agcaagaata
    12361 cgtgattcat aattaccccg attattttga agatattcag gacagaccca tcaaataaga
    12421 ggttttggaa tcagcgtttt gacctgagta ttagagaaag aaacggcaaa atagttcctc
    12481 atattttgcc gttttttttg agctaatacc gagggtcagc tgattgcaca ccgtttattg
    12541 agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta aaaatagctt
    12601 cttatgtttt taacttggct ggacttatta ccgcagatgc aagcttttga acaccgtttt
    12661 ccaagaggtc gtgagcctgc cgttcatctc cgagtcacaa ggaacaattt caaaaaacag
    12721 cttctcatgt ttgttgaata ttttgacttg tgaccgagga gttgacagga gaacatcgtt
    12781 tattcggaaa aaaaggactg tgacacgact tttgtcacag tctctttatt tgtaatctaa
    12841 atcatactcc gtacatcttt tttctatttt ttttatttct tctaagatcc cttggctacg
    12901 aatttcatta tatggccaaa gtaagactgc ctctaataca taaggcgaaa aatcgctttg
    12961 attcatctct tttgaaaaac tcatcgctgc tatctcgctc aatgcacgaa tgtttgattg
    13021 atgtgtataa aaaggcaacc gccacagcac aattttttcg ctttgcgtat aaattccctt
    13081 aacagaagct tcgatgtggt gaaatagttc atgtccaata atcaaagctt gcgctgtttc
    13141 tttagagatc gaagctagtc ctgaacattt taatttttct aacggctccg tcatcaatcg
    13201 aatcccttca tcttctgcat aagttgcaaa agtgattcgt tcgtttattt gctctgattc
    13261 acaggaaacg attggaacag ccatttgttc acaaatttct cctacatcgg caaaagggta
    13321 cttttttttg atgctacatg ccgtttcgat accacaatcg attgattgtt gtataagaat
    13381 tttctgcttg gacaaaggaa tctttttcca aaataaatct cgccgaaact ggtagaatcc
    13441 ccaaatttct tcggggatct gttgtaattc gtttagtaac tcttctaact tatgtttgtt
    13501 tgatatttcc ggcaacgacg atcacttctt cctccggttc catagtagat acttccagat
    13561 ccatcaaaag ctgtagttgt tccagatccg tcgctgtaaa atcagagact cttgctccta
    13621 agcagagata aaattctggt cgggcaatca attcagtttg ataaactgcc atatcttccc
    13681 aaagttgttc gacagctgtc atataattgg ctgcagttgt tttcatacat gaagcatgtc
    13741 cacgttggac cttgataaat cctttttgat cgatgatccg aagacttcca gcattttttg
    13801 aacgattctg ttcgccgcat acataaaaga aaggtgtatt ttccaataag caaacttcat
    13861 ttttatttaa tcgcatatcc tctgcagcaa gctctagtgc ttcttctgtt gtgatctcct
    13921 tggttagatc ggttgctttc acttccgtag aaccagtagc gatagccgtt acttttgaag
    13981 tctgtggatc gatttctacg tggacttcga tcgattctgg tgtagcgcct gattcaatcg
    14041 ctttattcat cgcttcattt ttcaacgatc gtatatcttc tttacttggc gaagggatga
    14101 tacgttctac aacatctcgg accattgcaa gtgctacacc aatagaagaa atcacttcgg
    14161 cgttttcagg aatcgaatat ttcacaccca ttttattact aaagtaagta atcaatgagg
    14221 cagcgccgcc ccctacacct acaagagaaa tctgatcttt ctccaagtga tacttgtctg
    14281 ccaattctaa aatcaccggt tcaatcttag cataggattt ttccatgatc tgttctgcga
    14341 tgtcttcaac cgtcgtatga caataatcag ctaatgcttg gatggctttt cgtgcagatg
    14401 ggacatttcc ataagaaaaa tgttcttctt gcactaatcc aaggacattg gctgcacatg
    14461 tatttgtaat agtcacttct tctccgtctt ccatcactac cttgacgtaa tcagcagggt
    14521 ctccttcttt aggagagaaa aattcaacct taggaccttt gattttttct gtctccgtaa
    14581 atactgcata atctagaccg gcaatatgtg cagaacgtgg accgacatcg atgattcctg
    14641 actgattagc ccgtaccatc gaaccgcctg ccacacctag aacccgaaca tctaatgaag
    14701 agatatatgt tgggtggcca cctacaattg aataatcgat tgctggacgt ccatttttaa
    14761 tgaccccgat attggttgtt gttccgccta cttcaaaata aacaccatta gacgctctca
    14821 agtacatcaa agagcccatg actgatgctg ctggaccgga aagcatggtt aaaacaggtc
    14881 gttttttcat ttcattgatt tccattactc cgccgtctcc gcgcataatc atcaaagaaa
    14941 cattgacccc tgcttctcgt acggaatctt ctgtagaggt tgccgtatct agcatttttg
    15001 gtaaaataga tgcattgatt gctgctgtcc gagttcttct tgtcaatcca tataattttg
    15061 tgatgtcaga agccatcgtt gtagggatcg attttaccga tgctgcttca taaacaactc
    15121 gttctggttc cccattatct actccaaatg ccatagaaga aaccaagacc tccgctcttt
    15181 ctctttctaa agaagaaatc gtttctgaaa cacggtctac atttaagtgt ttgacaggta
    15241 agaatgcatt gacaatctct atttttttct tattccctaa atcgatatcg ttcaatctag
    15301 tttgtcgttt tgctaaaaaa ccttctaatc caccttttgc catcccgatt acgccgactt
    15361 ttgctacgtc tccttcaatc agtgcattag tcgcttgtgt ggtagaatgt gcaacaaaca
    15421 caacatcttc tggactgata ttattttcca gcaaacaatt ttgaaaagac tgaacgacac
    15481 ctgcggctac tccacggaca tcatcgtggg ttgttttcac tgaagatttt ccgatgattt
    15541 cgtgcgtcgc attatcgatt gcgactgctt tcgtatgtgt accgccaaca tcaattccca
    15601 ttcgcacaaa acgtttcatt ttcttttcct ccattcatct aatcgttttt atcgacgttt
    15661 tgtttactag gcgttcccgt acaataagaa cgtgatcagg cataagatcg ctccgatgat
    15721 ccaaccagtt gggatggatt tcttcatata ttctcgagaa gttacttttg tataacctaa
    15781 tccccaagca acccaagatt gtgtaatatc taaatgctga ggagcaatcg ttgtgattgc
    15841 aaataacggg aacaaaaagg ctggcgacat cgttggatta acagctaata cgacagctaa
    15901 aatagctgag cctgaaccga ctagattcat tggaccgcgg aaaaatccta gtggtgtcaa
    15961 tatagcaaat acgattgcca agactaatgg tgattgcggt atccaatctc caaaaatagc
    16021 tgaaaaataa ggagaagcat acgcagctga attattgaac atcgctaagg tcatcaagaa
    16081 accaaccatt ggcgcaacat ctactgcgcc atctgtaaat aatttcgcaa actgacgaca
    16141 gatttcttta taacctccgc gcaattttcc agtaaacagc aatgcccaga tacctgctag
    16201 aataaaacct aagatgattg gaagatctaa aagaacgacc cctaaaactg gtaataatac
    16261 ggctaaccat gagatcattg gtgcgtcgcc accttcagct ggtacgtttg ctgccattgc
    16321 atagcgtttc tttttgttca ttgatatatt agcgaccgtt agtaccacaa ctaagcttac
    16381 aatcatccca atcataccaa tttggaaata gtcattataa gtatagcttt cagccgctgg
    16441 attgaaacca gcataaatcg tttgatattg tttgaaattg acgatattag caaagattcc
    16501 agccataatc gagcccataa atgagaacag tgcaaccggt actgaaatac ctaatgacat
    16561 caagattggc aacacaataa ctgcaataga aatcactggt ccgattcctg tcatcgacat
    16621 gaatataaca gcggttacaa tacatagtaa gctcatcgtg attcttggct tgtcccctcc
    16681 aagttcaact acctttcgaa tcagggtagc tgcgattccg ctatctacta gaacacgccc
    16741 gaaaaaggca ccaaagaaga catttaccaa gatcgatttg gcgtactcag ctggccccgt
    16801 cgtatagata tgcgtcaaca catcaattac tccttgccct tccatcgccg ggtttggtga
    16861 aaacgtgttt ccgactagcg ctaatcccat ccatacagta gccatgatgg caaagccgac
    16921 catcaagttg tagcctttta cacagtacca gaccatgaaa aagaatgaga taactaacaa
    16981 aataccaata ataatatcac tcatgttatt cctccgtcca ttttgttttt ctgataagca
    17041 aactaatata tcagtcaaac tcattctaac ttatgtagtt agcgctttca ttaaagggtg
    17101 accataaatg ttcagttttc aattaaaaaa ccttaattat gctattttag acttatacgt
    17161 tattgtcctg tttcatttga tggaggattg taaataaaaa aagaggaaag aacataactt
    17221 ttcgttatct tctttcctct ttataattgt ttagcttatt tagccaaagc ttcttttgct
    17281 tggtcagcca atgcagtaaa tgctgctgca tcgttaacag ccaagtcagc taacatttta
    17341 cggttgatgt cgatttcagc aactttcaaa ccgtgcatta attttgagta gctcaagcca
    17401 ttcatacgag ctgctgcgtt gatacgagca atccacaatt tacggaagtc gcgtttcttt
    17461 tgacgacgat cgcgatatgc gtagttgtat gaattcatta cttgttcttt tgctgtttta
    17521 aataaagtgt gttttgaacc gtagtaacct tttgctaatt ttagcactct tttacgacgt
    17581 ttacgagtta ctgttccacc tttaacacgt gccatgtata attcctccta ataaaaataa
    17641 atcttcagat tctgttattt gtacttctta tttcattttt gctagttgtt ggcgaatacg
    17701 tttgaagtcg ccactagaaa ccatgcttgc tttacgcaat tgacggcgtt gtttttttgt
    17761 tttgccgtgg aaacggtgac ttgtaaacgc gcggaagcgt ttcaatccgc ctttaccagt
    17821 acgtttgaaa cgttttgctg atccgcggtg tgttttttgt tttggcatga ctatatttcc
    17881 tcctcaaaat ctttcgttat ccgactatcg gctgtccaac agccagttag tcattcaaat
    17941 tacttactgt cgtttttcgg tgccagcgtc aagaacatgc tgcgtccgtc cattttcgct
    18001 ttttgttcca ctgttgcaat atccgcagtt tcttcagcta agcgattcaa gactttttga
    18061 ccaatttctt tatgggtaat ggcacggcct ttgaaacgga tagaagcttt cactttatcg
    18121 cccttttcca agaacttacg tgcattacga agttttgtat tgaagtcatt caagtcgatc
    18181 gtaggactta agcgaacttc ttttacattg atcacttttt gttttttacg cgcttcgcgg
    18241 tctttctttt gttgttcgaa acggtattta ccgtagtcca tgattcgcgc aactggtggt
    18301 ttcgcaccag gggcaactaa cacaagatcc aagtttgctt gttctgcaat attcaatgct
    18361 tctgcttttg tcttaactcc taattgctca ccatctgaac cgatcaatcg taactctcgt
    18421 gcacgaatgc cgtcgttaac catcatatcc tttgctatgg tcattcacct ccaaatatta
    18481 tgagagaaag aaaagcttac cgaataaacg gcaataaaaa aacgagttct cttacagaac
    18541 ccgcgcgtac ttcacctaat agaaccagtg aaaactatct agcccagtga cattatcaac
    18601 taaggcgaga agcgggtgct tctgctttta tttctcaacc atcatagtat agcaaaaact
    18661 aatctttttg tcaatgtttt tcatacagtt tgtcttcctt ttctgaaaat gattagatta
    18721 gcagactttc tagcagtgat tcccgcttct ttgctatact aaagaaaaac gaggtgaacc
    18781 cacatgaaaa aaatcgaacc tattccacct tctcttcctc ttcttacaaa gggagagttt
    18841 tatttagaag atgaggagat cttctctggt cttctgatca acgggggtga ccaaagctat
    18901 ctcgatgcca aaaatatggt attaagagag agtcatatcc aaaaacttac gatgcaaaaa
    18961 acagttttac gtcattttga atgcagtaat gtcatttttg aaaaatgtga tttttccaat
    19021 ctggagtgga ttggtggcag tttccaccaa gtcgtgtttc atcaatgtaa attaacaggt
    19081 acgaattttg ccgaaagtta tcttcgagac tgtactttca ctgattgtat tgcttcgatg
    19141 gcttccttta gtagtacaaa cttgaaagct gtctccttcg atcattgtca attagaagac
    19201 agcgaatttt atgaggtcac ttggaaaaac ctttttttgt ctgacaatca gttgaccggt
    19261 tcgaactggt ttcgaacttc tctgaaggga ttagacttta cgactaattt cttcacagca
    19321 atcgctttat ctcaagattc tttggcggga ctaatcgtca accaagagca agcacttgtg
    19381 atcgcccaag cccttggttt gcagatcaaa gactagatca acgaatccgc cgccacagtg
    19441 caataagcat ccaaatagat aagaccaaac tgatgatcaa ggcgattccc catccgaaaa
    19501 cggaatgggt aaagggtaac tggagattca ttccgaagaa tcctgtcaca atagttggaa
    19561 cggtcaagat cagcgaccag accgtcaaaa atttcatcgt gtcattcaag ttgttattca
    19621 gcaaattatt ataagtgcca gagagctggt ctaaaatctg cgaagctaag ttcgtcattt
    19681 caactgcttg tcgtgcttcg atcagcgcat cgtccaactc ttctttttcc ttttctgaca
    19741 acttgcgata aatagccaat gccttgattt gttctaaaag tactacattt tgttttgttc
    19801 ctgtaactaa gtaaaccaaa ccgatctcta aatctgaaag ttgcagcaga ttcttgttcg
    19861 ttgttttttc tcttaatttc agattaagcc gctgacgttc actattcact tcctcgatta
    19921 aaggaaaaaa ggaatcagaa atcaaaaaca atgtacgaaa caataaactg tatacactca
    19981 tgtctggcat tcgttccaaa agcgatcgaa ttagtcgaat cacgtactcg gtattcggcg
    20041 tggtaaatgt aaacaaaccg tcttctttta aaataaaagc gataggacta gtttcataat
    20101 gattatcgac tttttgctgg tgcggaacat ttgatacaag cagtaacgct tcatcaaaag
    20161 aatcgtactc tacgcgcgcc cgttcatttt tatctagaga ataagtcagc atctcgtcac
    20221 taatgccata ttcttctttt aagtttttaa cagctagcac atcgttttgc tgtacattga
    20281 tccaaaaatt acggtcttga ttaaaatagt gtttttcccg catactctat cctcctgaca
    20341 tttgtttcca gtataaagaa aaaagtcgct caaataaagg tttacccttt atttgagcaa
    20401 ctgtaaatca aatggctact ttggtttggc gaatctctgc taatttttct tcgatcattt
    20461 tcaagacttc ttcttttgct tgaggatctt ccacaaaatt atagcggtct ccatcgattt
    20521 ggatttttgg actttctttg tattcttcat accattgatc gtaacgtctg ttcaattctt
    20581 tgtaataatc gtatagactt ggatcaaagg acaattgttc atacgaacga ccacgttttt
    20641 cgatacgctc caacatcgta tcaaaagata cacgaatatg aactaataaa tccggatgtt
    20701 ttttatgggc agcataggga agttcttcca tcatgttttc cagcagttca tcatacacac
    20761 gaacttctgt ttctgttgct cttcctagat ctgcatttag atggaaaagc agtgaatctt
    20821 cataaatcga acggtccaat acattattgt catctttcat tgcttgtttg atgcttgcaa
    20881 aacgtttatt caaaaaataa atttgcagca aaaaagcata ctgttcaggg tttgcataaa
    20941 ataagggcaa gacttcatta tcatcaatcg attcataaaa tgcctgacta tcaaagtgtt
    21001 cagccatcat ttctgttaaa cttgattttc cggcaccaat tgtacctgct aaaacgatca
    21061 cgctcattta cctccagctc acttcatcac taaatattgt gtttaactcc aaccttttta
    21121 aatatacccc caatatctag tagtgtcaat tgtatttttt tctagtcaaa gaagaaaaaa
    21181 agtcaaaaaa ttcttaagaa aaaagtgttt tttctttaga aaacgtattc ttagttttac
    21241 ttctgagatg gttttagtaa aataaaggag gaatgttttt tgagaccctt agtggacaaa
    21301 aaaattcgtg aagcagcgca actcgttttg ggcgctttat tttttgctta aaaatcactt
    21361 ttacgtgaga aggagttaga ttatggcaaa ctatggccaa ggagaatcaa gcggaaagat
    21421 catattgatg ggcgagcacg cggttgttta tggagaacca gcgattgcct ttcctttcta
    21481 tgcaacaaaa gtcaccgcat tccttgaaga gctggatgca atggacgatc aactggtttc
    21541 ttcctactat tcaggaaatt tagccgaagc tcctcatgca ttaaaaaata tcaaaaaatt
    21601 attcattcac ttaaaaaaac agcatgacat ccaaaaaaac ttgcaactga ccattgaaag
    21661 cacgattcct gctgaacgtg gaatgggatc aagcgctgca gtcgccacag cagtcactcg
    21721 tgctttttat gattacttag catttccttt gtctcgtgaa atactattag aaaatgtcca
    21781 gctttcggaa aaaatcgccc atggtaatcc tagtggaatc gatgcagccg ctactagcag
    21841 cttgcagccg atttatttta caaaagggca tcctttcgac tacttttctt tgaacatcga
    21901 tgcttttttg attgtcgctg atacaggaat caaaggacaa acaagagaag ccgtcaaaga
    21961 tgtcgctcac ctctttgaaa cccagcctca tgaaactgga caaatgatcc aaaaattagg
    22021 atacttgacg aagcaagcaa aacaagcaat cattgaaaat tcaccagaaa cgttggcaca
    22081 gacaatggat gaatcacaat cacttctgga aaagctgaca atcagcaatg attttcttaa
    22141 tctattgatc caaacagcaa aagataccgg ggcattgggt gccaaattaa ctggcggtgg
    22201 acgcggtggc tgtatgattg cattagcaca aacaaaaaca aaagcccaag aaatcagtca
    22261 agcacttgaa gatgcgggtg ctgctgaaac ttggatacaa ggattaggag tacataccta
    22321 tgtttaaagg caaagcacgc gcatatacca acattgctct aatcaaatat tggggtaaga
    22381 aaaatgaaga actcatcctt ccaatgaaca acagcctttc gttaacattg gatgcatttt
    22441 atacagagac agaagtcatc ttttctgata gctatatggt agatgaattt tatctagatg
    22501 gcaccttgca agacgaaaaa gcaacaaaaa aagtcagtca gtttcttgac ctttttcgta
    22561 aagaagccgg cctctcacta aaagcttcag taatcagtca gaatttcgtt cctaccgcag
    22621 ctggattagc ctcctctgcc agcgggctag ctgctttagc aggcgcttgc aatactgctc
    22681 ttaagcttgg attagatgat ctctctcttt caagatttgc tcgacgcggg tctggttcag
    22741 cttgccgaag tattttcggt ggtttcgtcg aatgggaaaa aggccatgac gacttaagtt
    22801 cttacgctaa gccagtccct tccgattctt tcgaagacga tttagcaatg gttttcgttt
    22861 tgatcaacga ccagaaaaaa gaagtgtcca gcagaaatgg gatgcgtcgg acagtcgaaa
    22921 catccagttt ttatcaaggc tggttagatt ccgttgaagg ggatctatat caattgaaac
    22981 aagcaatcaa aacaaaagat ttccaacttc tcggagaaac gatggaaaga aacggactaa
    23041 aaatgcatgg aacgacttta gctgcccagc ctccattcac ttactggtct cctgacagct
    23101 taaaagcgat ggatgcggtg cgacaattga gaaagcaagg cattccatgc tactttacga
    23161 tggatgctgg ccctaatgtc aaagttttag tggaaaacag ccatttatct gaggtacaag
    23221 aaacatttac caaattattt agcaaagaac aagtaattac tgcacatgct ggtccaggaa
    23281 ttgcgattat tgaataaagg gagattttta tgattgaagt atctgcacca ggcaaactct
    23341 atattgccgg agaatatgca gttgttgaaa caggccatcc agcagttatc gctgcagtcg
    23401 atcaattcgt gacagtcact gtagaatctg cacgaaaagt cggaagtatc caatctgcac
    23461 aatatagtgg gatgcctgta cgttggacaa gacgcaacgg agaattagtt ttagatattc
    23521 gggaaaatcc ttttcattat atccttgctg ctattcgctt gactgaaaag tatgcacaag
    23581 aaaaaaacat tcttttatcc ttttatgatc tgaaagtaac aagtgagtta gacagttcaa
    23641 atggccggaa atatggattg ggttctagcg gtgccgtgac cgttgcaacg gtcaaagcct
    23701 tgaatgtttt ttacgcgttg aatttatctc agttggagat tttcaagatt gcagcactag
    23761 ccaatttagc agttcaagat aatggttcct gcggcgacat cgctgctagc tgttatggtg
    23821 gctggatcgc tttctcaacc ttcgaccatc cttggctcca agaacaagaa actcagcatt
    23881 ctatcagtga gttacttgcc ctggattggc caggtctatc cattgagcca ttgattgctc
    23941 ctgaagattt acgtttattg attggttgga cgggtagccc tgcctctact tctgatttgg
    24001 tcgatcaagt tcaccgttcg agagaagata aaatggtggc ttatcagctt ttcttaaaaa
    24061 atagtacaga atgtgtcaac gaaatgatca aagggtttaa agaaaataat gtaacgttga
    24121 tccaacagat gattcgaaaa aaccgacaat tactgcatga tttatctgca atcactgggg
    24181 tcgtcatcga aacgcctgct ttgaacaaat tgtgtaattt agctgaacag tatgaaggag
    24241 ccgcaaaatc ttctggtgca ggtgggggcg attgcggaat cgtaattgtt gaccagaaat
    24301 ctggcattct tcctttaatg agtgcatggg aaaaagcaga aatcactcca ctgccgttac
    24361 atgtctatag cgatcaaaga aaggaaaacc gatgaatcga aaagacgaac atgtttcact
    24421 agctaaagcc tttcatgata aacaaaaaaa cgaatttgac ttcgtacgga tcatccataa
    24481 ccctttgccg caaatagcag tttctgatgt cgatctaagt acacaggcag ttgggtttac
    24541 actaagcagc ccattttata tcaatgcgat gactggcgga agcgaaaaaa caaaaaaaat
    24601 caaccaagat cttgcaatcg tcgcaagaga agcagatttg atgattgcca ctggttcagt
    24661 cagcgctgcc ttgaaagtcc cttctttagc cgatacttat acgattatgc gacaagaata
    24721 tcctcacggg aaaatcattg ccaacatcgg tgcagggact tctgtcgaaa gagccaaaga
    24781 agctatccga ttgtttcacg cagatgcctt acagattcat ttgaatgcac ctcaagagtt
    24841 ggttatgcct gagggagacc gtgattttac caattggaaa gtacttattc aagaaactca
    24901 aacagccatt gacgtccccc tcatcgtaaa agaagtcggt tttggcatga caagagaaac
    24961 gctcaatgat ctagctgctt taggagttca tacagttgat atcagcggtc gaagcggaac
    25021 aagcttcacc cagatcgaaa acgcccgtcg ctccaagcgg gaactgagtt atttagctga
    25081 ctgggggcaa tcgacagtct cttcattgct tgaagcaaat gaagcagaca cttctatgga
    25141 aatcctagcc tccggaggta tccgcaatgc ctatgacata tttaaagccc tttgtctcgg
    25201 cgcaaatgcc gtgggtactt caggaaccgt actgacgcat ctgatgaatc acggcgtaga
    25261 agaaactatt atactgatga agcaatggca agaagagctt cgtctgcttt atactatggt
    25321 cggcgcaacg aataccgcgg ccctacacca acaatctctg atcttttccg gaccagtgaa
    25381 ggattggtgc gaagcaagag ggatcgactt agtgaagtat ggaagacgca cagaaaagag
    25441 cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtaca aacggcggaa
    25501 gtaaaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaattttcg
    25561 tgaattcctt cttatttctt ggagttaaat gcttctgtcc cagcctcttt tttcgaataa
    25621 atgatgttta atcagctgtc cttcggtatt cgttcaatcc gctgatttca caacctctcc
    25681 actaaacagt gtactaaagc tcttttaagg ttgttttccg atataggcaa gtatgcctcc
    25741 gtccacatac aagacatggc cgttaacgaa atcagatgcg ctagaagcca agaagacaga
    25801 tggtccagcc aaatcgattg gctcgcccca gcgtgctgct ggcgtacgtc caacgataaa
    25861 ttgatcgaat ggatgacgtt caccgttttc ttgtgtttcg cgtaatggag cagtttgcgg
    25921 tgtagcaata taacctggtc caattccatt acattggata ttgtattgac cgtattcaga
    25981 agcgatgttt ttcgtcagca tttttaatcc gccttttgcc gcagcataag cactgaccgt
    26041 ttcgcgtcct aattcactca tcatggagca gatattgatg attttaccgc cgcctttttc
    26101 gatcatatcc ggaataactg cttttgaaac gatgaatggg gcatttaaat ccacgtcgat
    26161 tacttggcgg aagtctgccg catccatttc gatcatcggt gtccgtttga tgatccctgc
    26221 attgttgact agaatatcaa ctgaacctac atcttctttg atctgttgaa ccatcgcttg
    26281 aaccgcttct tcatcggtca catcgcagac ataacctttt gcatcgatgc ctgcttcttt
    26341 ataatgcgct ataccttcat caactgattc ttgattcaag ttattaaata cgatttttgc
    26401 tcctgctgta gctaaagagc gtgcaatctc aaatccaata ccatagacag caccggtgac
    26461 taatgctact tttccatcta aacgaaacat atccatacta aattccatca ttttctctcc
    26521 cttatgctta ttttaattga tccatttgca ccatatccat gtctgtatag gtgatatttt
    26581 ctccgcacat tgcccagatg aatgagtaat tgcttgtacc tacacctgaa tggatcgacc
    26641 agcttggcga aataatggct tgttcattgt ctacaactaa atgttttgtt tcatctggtt
    26701 tgcccatcat gtggaacaca cgtgtatctt cattggcata atcaaagtag acataagctt
    26761 ccatacgacg ttcatgtgta tgacaaggca tcgtattcca agcgcttcct ggttctaaaa
    26821 tcgtataacc catttgtaat tgacagcttt cgcatacatt tggatggatg tattggtaga
    26881 ttttacgttc attcagtgtc aggccttcac cagtctccat tggttttact tggtcgatac
    26941 tgatttttac atttggatat ttatgatgag ctggaacaga actaatatag aatttagctg
    27001 ggttttcagc atcttgagaa gaaaatacaa catgtcgtgt ttcttttccg atatagtatc
    27061 cgtcttgttt tttcatttct tctttttgcc catcgatctc gatgaatcct ggtccaccga
    27121 tattgatcac acctagttca cgacgctcta agaagtaatc aacacctagt tctttgtcta
    27181 atgtgatttc taattctttt tcagtaggtg tcactccacc aaagatcatt cgatcgttgt
    27241 gcgtataagt caaactgatt ttccctggtt caaatacctt ttctactaaa aattcttttc
    27301 tcaattgttc cgttgaataa tgacggatat cttctggact gtgtgtataa cgtgtttcca
    27361 tttcttgcat tttcttctac tccttctatc gaatgatttt tccagagccg catgctaaaa
    27421 attgtgcgac ttcttcttga ctaaattggt tgcagtcccc atggatcgta tgcttcaagg
    27481 cagaagctgc cgtagcaaaa tcaatgattt cttgcggaga catattggat aaaatcccat
    27541 ggagcacgcc acctgcaaaa gcatctccgc cacctactcg atccacgatt ggggtgattc
    27601 tatggacttg ggattccaca tattcatggt tcatccacaa tgtccccttc aattcatttt
    27661 cacttgctga atgaacggta cgcttggtcg aataaaacac ctgaatattc gggaactttt
    27721 cctgcatttt ttgataataa taaattagag gttgttcttc tgcttctggc gctttctcga
    27781 tacctaacaa ataaagagca tccatttttc cagctgagca gatatctact aaaggtaaaa
    27841 gctgatggat tacttcgctg gcttcttgct gtgtccataa ttttccacga tagttgatat
    27901 cgaagctgat caggcagcca gctttttttg cagcttctat cacctgtttc gtcatttttt
    27961 gccatttttt agacaaagct ggggtgattc ctgaaacatg aaatatatct attccttgga
    28021 ataactcctc tagcgaccat tccaaatgat ccatttcagc aaaacttgat ccggcacgat
    28081 catagatcac tgaggcggcg cgttcgccac taccagtttc catataataa gtacctagtc
    28141 ttgatccacc agataatacc tgtttcgtat ctactccata acattgcaag tgctttttga
    28201 ctgcttttcc caatgcgtta tcaggtactt ttgtagcaaa aatcgcttca tgtccgtaat
    28261 tagctaaaga aattgctacg tttgcttccc ctccgccata atgggcagcg aatcgttcac
    28321 ttgaatcgat acgggttccc tgctctgtgg acaatcgcaa catgatttct ccgagtgtca
    28381 ctacttttcc cataagcagc tacctcttga tttctttcat ttttgctgca tactgttgcg
    28441 cgacttccgt tactttgtca aaatctcctg tagctgcggg tgctaaaagg ttcccaccta
    28501 ctccgactgt tacgacacca gcatcgaacc actctttcat attgtccaga ctcacaccgc
    28561 cagttggcat gatattgact tgaggcatcg gcgccttgaa ggcagaaatg atacttggtc
    28621 cataagcgct tccaggaaat agtttgacga tatctacccc gcttttcagc gctgttttga
    28681 tctcggtaat agtcatacat cctggtaagt aaggaatttg atacagattg cacatctctg
    28741 ccgtttcttg atcaaaggaa gggctaacaa tatactctgc gccagctaag atagccaagc
    28801 gagctgtgac agcgtctaat actgtgcctg cgccaatcac tatttctggt tggtctttgt
    28861 agaatgacaa aagttctttg attacttgat ctgcttgagg gactgtaaaa gtcaactcaa
    28921 taccagttag accacctttg atgattgcgt ggcaagcatt caaagcttct tctttgcttt
    28981 ttccgcgtac caccgcaatc actccggcgt ttttcaatcg agataaaata tcaatttttt
    29041 tcatcttctc cacctatttc ctatttagaa attttatttt ataacttgga aatctatacc
    29101 catattatac ggcagaaaag aaaaattgca aacgcttttt tcattatttt tgaattcttt
    29161 gctcgatttc gctttttgtt tgcttgaggg cactgattat ttgttctttt gtctcatctg
    29221 ttaaacgata tttcggcata cttacactaa atgcaccaat gatttgttcg tttttcacga
    29281 ttgaggctcc tatacaaaaa atatcacgtt cgatttcttc atcgtcaaat gcgatgtggg
    29341 tttcttttac cgttttgatt tcctttttca accgtaatgc attggtgatc gtatattctg
    29401 tgtaagggat caacggatgc ttttcaagat aatcagtgta ctgctcttca ctgaattctg
    29461 ctaatacggc tttgcccatc gcagaattgt ataatggtcg ggtgattccg atttttgaag
    29521 acatgcggat cgtttgatgt tttggatcta gtttgttcac gtacaagatc tcattgttgt
    29581 ccaatacccc taagtggata gtctcatcga tcttttgctg cagctgttct aaaaacggta
    29641 aagtcaactc taccaaatcg atttgttcaa tgtttttatt cgcgtagcga ataagctttg
    29701 cacctaaacg atagtttttc tctgaatttt tatttacgta gccgatcatc aacaaagtat
    29761 ctagtatttt caagactgta gaagaggtca ttcccacacc ctttgcgatc gtctgcaaag
    29821 agacatcttg gttttccgct aaatagtcta gtattttaga ggctttgatc aatacagttc
    29881 cataaggctt tttattttcc atataatatc ctcctatttc tttataagaa aaattatagc
    29941 ggaaatacca tcaatttaaa agagatatcc agatataaac taccatttct ctttacaggc
    30001 aatttaatgt tgaagatccg cttcgttttt acatcaaact ttgatataaa gcaatgattt
    30061 cttctactgt cgtttctctt ggatttcctg gtgtgcatac atctcgcaaa gcatcttctg
    30121 caattgctgg aatatctgct tcttttacac ctaattcaga aatggtttct gggattccaa
    30181 ccgctttgct caaccgatcg atctcaccac aagccgcttc tcttacatct tctaaagaca
    30241 tttcagctgc tcctttaatc cctagaacaa gagcgatctc acggtacttt tctccagtat
    30301 attctttgtt atatttcatg acagttggca aaagtgctgc acacgctacg ccatgaggaa
    30361 tgttgtacca tgcacttaac gggtgagcca tcccgtgtac cagtcctaaa ccgacatttg
    30421 agaagcccat tcccgcaata tactgtccta atgccatttt ttctcgccca ttttgatcgc
    30481 catctacaga agcttccaaa gaatggccga tgatttcgat tgcttttaaa tgcagcatat
    30541 cagtcatttc ccaagcgcct tttgtgataa acccttcaat agcatgcgtc atagcatcca
    30601 tacctgttga tgcagccaat tttttcggca ttcccatcat catatcgctg tcgatgaacg
    30661 cgacgattgg gatatcatga ggatcaacac aaacaaattt tcggtgattt acttcatctg
    30721 tgatgacgta gttgatcgtt acttctgctg ctgttccaga agtcgttggt atagctaata
    30781 taggtaaaca tggatttttc gtatcagcaa caccttctaa actaatgacg tctgaaaact
    30841 ctggattcgt caaaataatc ccaatggctt ttgccgtatc gattggcgaa cctccaccga
    30901 ttgcgatcaa acagtctgcc tctgcctctt taacaaaagc cactccatct tttacatttt
    30961 ggatcgttgg attaggtacg atcccgtcgt ataaagcata agcgattgct gctttatcta
    31021 gaagttctgt tacttttgtt gctataccgt gctcgatcaa tcctttgtca gtaatgacag
    31081 ctgctttgcc gaatcctcgc tgctgaaatt cagggacgat cgactcaatc gctccttttc
    31141 caaaatacga tgtttcattt aaaatcattc gattactcat tttctattcc tcctaatttg
    31201 tattattttt cacaataaaa acgaaagaac cccaagcaac cggttgccca gttgcttgtt
    31261 gctacagttc aaagactggc atcaattccc aactgactgg agaggcatct ggatttgtct
    31321 ccatgatatc ttccatgtac ttccaccatt tttgattgat agatgtattt gccatttttt
    31381 cccataactt ttcatcttcg atcactaagt aaccaaataa caaacttgta ctcggatcaa
    31441 gatagatcga atagtcgatg accccgtgtt cacgaagtgc tgtacgcatt tctggccaaa
    31501 gttcatcatg tctttttttg tattcttctt gtttttctgg gtaaactttc atgcaaaaag
    31561 cttttttcac catgtcagac acctgctttc gtatgaactt cctccaaata acctgctttt
    31621 ggagtgacac caaacgcatc tgctaaatgc cacaggtttt cgtccgtgat tgtttgcaag
    31681 attggtcctt gcgctttgac gtacgtatag acttctgctg ccttttctgc tgtctcgatc
    31741 aaaccaaaga cttcatccat gtcttttcct gacccgtaga ttccatgttg tggccataaa
    31801 accaatcgag tttctttcat tttttcagct gttgcttccc caatctcatt tgttcccgga
    31861 accatccacg gaatgatgga aattccttct ggaaaaacaa ctaagcattc cgtacacatt
    31921 tgccatagcg tacgactaaa ggaacgttcg tctaattcat gcgtaaaact catcgctaat
    31981 agatgactag catggcaatg cataacgatc cgattatctg ggtctacttc taaacgggcg
    32041 atatgactca tgaaatgact tggcaactcg cttgtaggaa ggcattcgtt ttccagcccc
    32101 cacaaaagtt ccagtgtttt gccatcttca gcaactcgaa cgattccaag attctcggca
    32161 ggttcgctcg ctacattttt aaaatatctt cctgaaccag ttacaataaa atagcatcct
    32221 gctaaacggc tggcatcaaa aatcatcgag atgcggcgga tcactttttc aggatccaag
    32281 aacggtgtga tctcttcttc ttttagtaaa taagaaatat tcccgccatt tctttcatcc
    32341 catcccaagc gataaagatt cgacgtcgtt tcgatcattt ctttcacata aggcgcttgt
    32401 aaaatatcta tttttttcaa tatagccaca ctcctatttt cttaattcca acacgtcttt
    32461 ttgatattcc tggacttctt ccagccaatc caaaccaact ggaacttgat ttttgtaaca
    32521 gaaataattc catacatcgg catacgggaa atctttcaat tcttccgtat aagccattct
    32581 tgaagtaaag tcaaaagcca gctccatttc tttcaatcgc tcaactggtt ccagcatagc
    32641 tttcagcagt gctttttgtg tatttctcgt accgatgacc caagcagcga tacggttgat
    32701 cgttgcatca aagaaatcca gaccgatatt tgttttttcc aacaattcgt tacggactaa
    32761 ttctttagcg atttcctgca attcatcatc catcaaaacc acatggtctg aatcccaacg
    32821 cactggacgg gaaacatgca acatgattcc tttgctgaat aaagctaatg aagataattt
    32881 attggaaatc acttctgttg gatgaaaatg tccagcatct agacaaacaa gtttgtcacg
    32941 agtcaacccg taacccatat aaaattcatg ggaaccgact gtataagctt cagcgcctaa
    33001 accaaatagt ttgctttcta ctgcatcttg tacataccgt tcatctaact cttctgtaaa
    33061 aatttcatcg agtgattcca ttaaacgttc ccgtggggta aaacgatcaa tcggattatc
    33121 tttcatccca tcaggtaccc aaaagttatt gatacttgtt tgcccagttt ctttcccaaa
    33181 gtactccgcg attttgcggc ttcttttccc gtgttcgatc cagtattcac gaacttcttt
    33241 atctggatga gccaatgtaa agccgtcttt catcattgga tgcgaaaaga aagtcggatt
    33301 gaagtcaaga ccgatttctt ctttttttgc ccactctacc catttttcaa aatgtttcgg
    33361 ctcaatttca tttagatcga cagattcttc tgtatccaaa tagatagcat gaaggttcaa
    33421 tttgtgtttg cccggtatca acgaataagc cttctccaga tcttgtctaa gctcttcagg
    33481 tgttcgtgcg gctcctggaa aattccctgt cgccatgatt ccaccggtca attcgccatc
    33541 cggtgtcaag aaacctttga catcatctcc ttgccagcaa tgcatagaaa ttttgatgtc
    33601 ctgtatcttt tctagtacag catctgtatc tacaccgata gttgcatatt tttcttttgc
    33661 ttgttcgtaa tttctttcaa tcgtgttcat acgattactc ctttgatttt attcacgtac
    33721 cattccatcg tgttttgctt attttcatct gggtaaaaag tttcacatgg aaacgactgt
    33781 ttgattacat ttcttgcttg ttctatattc gaaaactgac ctgtactgag catttgcatg
    33841 gcaacattcc cgattgctgt ggcttcacta ggtcctgctt ctacaatgat tccggcataa
    33901 tctgctgtca attgattcag tagacgatta ttcgatccgc cccctacgat gtgcagcttt
    33961 tccaatttcg ttccagttaa gtgttctact ttgatcagct cttgtgcgta acaaagagca
    34021 agattatcat acacacaacg agcgatagct cccgatgaga cagggactgg ctgctctgtt
    34081 tcaaaacagt attgctgaat ctcttctatc atatttgggg gattcaaaaa tcgagggtca
    34141 ttgatttcca tcacttgctg cagcggtttt tcttttgcag caagctctgc caattccgca
    34201 taactgtact cgtactcttg cattcgggca acttcctgga tcaaccacat ccccatgatg
    34261 tttttcaaaa aacgcaccgt gttatgggca ccccattcat tcgtataatt ttcagaaaaa
    34321 gcattgcgag aaacattggc gatctttgtt tcaatcccta aaagcgacca tgtcccactg
    34381 ctgatataac cccaacgttc tccttgacct ggcgttccta atacagctga cgccgtatca
    34441 tgacttgcta ctgtgataaa ggtcacatct ggcaaatcat attttgaaaa ttgttctttt
    34501 tgcagatctc ctagtatcgt tcccggctct gtcaatggtg gaaataattc cttcgagaca
    34561 ccgatttttt caagaagttc tatttcccat tcttttgtcc ctgcattcag cagctgcata
    34621 gtagatgcat tagttttctc cgtcaccatg ttaccagtaa agacataccc taaataatca
    34681 ggtatcagta acaatttatg tgcttttgcc aaattttctt tttcttcagc aaacaattgg
    34741 aacaaggtat tgaaaggctg gatctgaatc cctgtctgct catacaactt atctagagaa
    34801 tagatttcag aaaactgttc tactgctcca ttggtacgct tgtcccgata agcaatcgga
    34861 tcatttatcc gatccccttg ttcatcaatc agacagtaat cgactgccca tgtatcgatc
    34921 cccgcaaaaa ggcgatcaat ccctgtctgc tttaattttt caaatccaat caaaatctct
    34981 ttgataagat aatcgatctt ccagcgatcg tgaccgtctt tgttccgaaa gccgtttttg
    35041 aaccggtgta cttcttccaa gatcaaagaa ccttttgcat ccctcgtact tttcattagt
    35101 cgtccgcttg atgcaccgat atcgatggca acaaatgttg gattcatttc tccacctctt
    35161 ttactttatt gttgattagc actttattaa taaagcgtta tcatttattg acaatgctat
    35221 cataatacag aatcttatat tttgcttcac actattttgg tatataattg cattatcttg
    35281 acaagttggg agtgtttaca tggattactg ggaaaaagcc aaccactcat ggtcggaaga
    35341 ctcaaaaaga gtgatcttga cgcctacaca aagaagcagg aatttatttt tttatatcca
    35401 agaaatcggt tacttcaaag caccaatccc ttactatact gaacgagcac atttaccttc
    35461 ttacttgata aagtttactt tgtctggcaa aggttcgctt acatataatg ataatcagca
    35521 acagctaaaa gctggagact tattttttat tgactgccaa gaatatcagc gttatcaaac
    35581 gatcagcgaa gaaccatggg aaatggattg gatccatttg aatggtcaga acgtccaatc
    35641 attttatcag gagttcacaa aagacggcca taacaccttc cattcaacag gagatccatc
    35701 agaaaacaag atccaccatt tgatcacaga attgatccac atgcaacaag gcacgaatgc
    35761 ccgtaccgat ttccagtcct ctgtagctat ccacgagttg ctgaatgaac tgattttgca
    35821 aaagtatcag ctagatttcg aagaagagga tattcccgcc tacgtttaca aactgaagca
    35881 atacttagac gaacatttca aagaaacgat tacacttgat caattagaac aacaattctt
    35941 attgaataaa tatcagctga gcaaagattt ttccaaattt atcggttctc caccaatcga
    36001 ttatttgatc agcaaaaaac tttcttacgc taaagacctt cttcggtata cagaatttac
    36061 ggttcgaatg atttccgaag aaatagggat tgagaatttt gcttacttta gccgcctgtt
    36121 caaagcaaaa acaggactat cgccgagaga ctttcgtaaa ttcagctgat tcatataata
    36181 tgtacgtcat tttttcaaaa tattttgaaa tatatagata aaaataaaat aaccgcagtt
    36241 tctgcttcta tgtaaacaac agcagctact gcggttattt tttagtgatc attctcattg
    36301 ttcatcttca aaatgttcat aatgaaccaa ctgtttctgt gtatcacgtt tcaaaaattc
    36361 tttaggcgtt atgccgaact ctctcttgaa tgctttcaga aaatgcggat aagaagaaaa
    36421 accactttta ctatatacag cactagagct gcggtattct cgcaacaagt gcttggcata
    36481 gatcagcttt ttcttcatta catactgatg aaacgtaaat ccagtgtact ttttaaattc
    36541 tcgtgtgata tggtatttgc tgacaaaaaa ctgcttttcc atttcctcta aagaaagcgg
    36601 atgagataaa ttttttgaga tatattgtaa catttgttcc acacgctcat taggaactac
    36661 agcattctgt tcttgcgcac tctcttcttt ttgtacaact tgattgagaa aaatcaagta
    36721 ttctaccaga gcttgttcat attttatgtc ttcaccgtaa atttttttat caggaggatg
    36781 gtcgataaat gataattttt gcttcaatac ttcctgttct atttgcaata cacgactcct
    36841 cttctctccc attggttgaa aacaagccga tagattagac catggcgtgg aacgactttc
    36901 tagaaaagaa ggggtgacaa agatatagac acgctcgaat acatctgaag attggcggac
    36961 gatacgatgc aaatcattgg aatggatgag cagcacactt cctgctttga tcgtaaattg
    37021 tcgtccgttc aaataaaaag tcgcttctcc ctttaatgta gcatggatct catagaaatc
    37081 atgatgatga tagatcgttt tattttggct gacgacatct ttgacatgat agatttcata
    37141 ctgatcagaa accatcgtat tgacttgttc accgctgatt ttcttttgga gcatgtgccg
    37201 cacctccttt tgttcactta tgcacaattt tattatacca cgttttttgt aatcaaaaag
    37261 agctgctttt atatactctt ataaaaaaga agagacgtgg catcttctag ccccgccccc
    37321 tccattctaa atattagtta accaacgtct tctttacatt attcaagaag acttcttcca
    37381 taacgaatcc catcatcttt tgtttcttca agaaccacat acaggtacgg acgattcttc
    37441 atgatgattt ctttgatttt tgtgtactcg atcacaccgt ctcccaaatt taccggcacg
    37501 attttttcct gttcgacacg aaaatctttc aaatgaaccg cacatatctt ttcaccaaaa
    37561 cgttcaaaag cttcttctac caattggact tgttcttgat aatcactact tgtgatcaaa
    37621 ttggtcggat ctaaaatgat tcctagatag tccgaatcta ctgcttggat cagctgctct
    37681 acccttgcta aagaatacac cggatgattc aaacctggtt ctatccccac catcatttgg
    37741 tatttttctc cagcttttac caagcgacgg ataacggaca cagcttcagc aaatgcttca
    37801 tctgtgaaat tttcttccgt atattggatt tccggcaaaa cacatccagt ttccgaagca
    37861 accatcgacg caccaaagga agaagcatag cgaagatact gctcgaactt tgtcagcaac
    37921 tcttgtcgta tcgttaaatc tggatgaatc atattgatat agcaacttaa aattcctacg
    37981 gtcacttctt gcttttctaa aactcgtttg acataatttc ccatcccaga attgatctca
    38041 tttgcgccag aaggtatttc aggaaacgaa agacctaagg cgagctgcag tgtatgaatc
    38101 ccttgttctt ttgttttttc tgcaagatct tctatcgttt ggacttcgga aagatcatgt
    38161 cctctaattg taatgttcaa cataactatt ctcctaactc agcatattgg gtagccacat
    38221 gacgatttgc gggaagtaag taatcaaaaa caagacgact aagataaccc cataaaaagg
    38281 aagaagcggt ttcagcattg cctctgcttt tacgcctcct acacttgcac cgacatatag
    38341 tcctgtacct actggcggcg tgatggagcc tacacacaga ttcatgattg aaaacaaccc
    38401 gtaatgtaca ggatcaaccc ctacacttgt gacgattggt aaaaatattg gtgtaaaaat
    38461 caagatagca ggcgccacat ccataaacat acccaccagt aataacacaa gattgactaa
    38521 taacagaata ataaatttat tatccgttac gcccataatc aacgaactaa ttgcctgagg
    38581 aataccggta aacgccatgg cgaaagacat catggaagaa gtagccaata agaacatgat
    38641 cgtccctgac attgctactg attgaaacaa catattaggt atatctttta gttttaccgt
    38701 tttatagtaa aacatagcaa tcaacaggga gtaaatgaca gctatcgctg aagcttctac
    38761 tgctgtaaat atccccgtca agataccacc gataatgatg acaatcaata gaaggctagg
    38821 aatcgcctct tttattattt ttccagcatg agccatctgt cctttttcga caacagggta
    38881 tttattcttt ttagcaacga tgaatgctac tagcatgatt cctagcgccc acaaagcgcc
    38941 tacgagataa cctcccataa acaaagcaga gatcgaagca ccaccagcaa caagtgaata
    39001 catgataaaa gcagtacttg gaggaatgac catacctgtc ggagctgacg cgatattgac
    39061 cgctgtcgca aacttccggt catatccttc ttccacttgc tgagggatca acactccgcc
    39121 aatcgcggta gaagcggcaa tggccgagct agagatggaa ccaaataaag cattccctaa
    39181 cacattcgta tgagccaaag cccccggcac gcgcccgacg aacaacatcg caaaatccac
    39241 tagtttctta gctatccctc cattattcat gataatgccc gagagaacga aaaacggaat
    39301 agcgatcagc gaaaaactat tgatacttcc caccattttt tgagctgaac taaaagcaga
    39361 aacatcaaac ggtataacta acaataaagt catcatcgat gagaatgcaa tacttatagc
    39421 aatcggcatc cctaatacaa gcaacacaac aaatacaaaa aataacacta atccggcttc
    39481 tattgccatt ttattcctcc atttttatat tttttcttga attgctggct tgttgcttaa
    39541 tgtatcgatt agattgatca ggctatagat aatgatgagt acccccgata caggtactga
    39601 cagataaaca tatcccatag gaatacttaa agaaggcgag atctgcccca ttgtcaatgt
    39661 gacagcattc catccgccat acaccatgat catcgcagca aataccagaa ataaactttg
    39721 aacaacaact tctaaaattt tacttttttt gccagttaat ttttcactta aaaccgttac
    39781 ggctaaatgt gctttttgtc ccacaacata cgcggaagac aacatggcaa accagacaag
    39841 accgaatcga acaagctctt ccgtgaccgt atttggattt cctaaaaccg ttctggaaaa
    39901 tacttgccat aaaacaacag cgaccatccc aacaagcaaa acagctccca ggatctctaa
    39961 taccttgttt aaaatcattt tcatcacagc tacgctcctt gctcttggat cttttgataa
    40021 aggtctttgt aggtaggatc gtttttgaat atatcatgaa gtggggcaac tgcctctcga
    40081 aacggtgtat tatctacatc attgaattgg actccatgtt cttcttgtgc taaagctttt
    40141 tcttcttcaa ttgcttttgc aaaagcttca atttcaaaaa ccgttgattc tttcgctgct
    40201 tcttcaatgg ctttttcctg ctcatcagtt agctgttctt tgatggcatc attcatgatg
    40261 atgatatctg gcacacgtgt atgctcatca taggaatagt atttagccac accaccatgt
    40321 ccagctgtat acaagacaaa ttcattgttt tctgatccgt tgatcaaatt ggattgaaga
    40381 gacgtgtaca cttcatcact tcccataggt acgggcgaac cgcctaaaag ctctaccatt
    40441 ttgatagcgg tttcgctttg catcacacgg atcttctttc ccttcaaatc ttccggcgta
    40501 tggatcggac cgtctaccat ataaaagctg cgctgaccag aatcataata ggtcaatccg
    40561 gtaaatccta aatttttggt cgattggtag attggctcca ttatttcttc attatccatc
    40621 accttaaaga aatgttcttc atcattgaat agataaggaa ctgaaaaaat cgaataatct
    40681 ttagagaaac tttccaacgc tgaggcactt acttttgtga aatctactgc tcctgactgt
    40741 gtcaattcga tcagttcacg ttctccaccc agttgtccat ctgggaaata ctggatctgt
    40801 acggaaccat ctgttttttc ttttactaaa cgcccaaatt cattcattgc atcaattact
    40861 ggctggctgt tgcttgcata agcaaagcgc aaggtaacta tctcatttac atctgcatct
    40921 gcgacagttg ccacactaga attatttccg cagccgctta gacctagcag acctaggcta
    40981 agcgaacttg ctgcaaacag cagtgatgtt tttttcatat gggtttcctt tcttttaaca
    41041 ataagagacg agcaattctg tcaaacaaag caccgttaac gactgtccat aaggcattgc
    41101 tgtgattccg atattccgat aaaaatctaa actgtccccc attcctgtcc cgattgaaac
    41161 gttttgaact tctccttttt catcgatttg ttcaagcaat ccttggatag cacgataagc
    41221 gacttcttta tattcttgtg gtaaataacg tttatggacc gctttcaaaa taccgtaagc
    41281 aaatcctgca gttgcagaag attctacgta agaagaagga tcatccaaca acgtatgcca
    41341 taaaccgctt tcagactgat aagtttttaa tgcacgcact tgtgcttcaa gtgtttcgat
    41401 caataatttg cgcaatgcat cttctttcga taattctaag atttcaatga tctctggaat
    41461 agcaatcgtc aaccagcagt ttccacgagc ccaaaatgct tcggcatagt tatgatttcc
    41521 ttcaaacgtc cagccgtgat accacaatcc tgttcgttta tccatcaagt atttgatatg
    41581 gatcataaac tggtaacgag cttcttctaa atattctggg cgattcaaca gtttcccgat
    41641 ttttgccaaa ggaagcactg tcatcatcaa tgtatcgtcc cacaactgat tcttattttc
    41701 cggtccatat gtggcatgct gtaacccgtc ttcatttgtc cgaggcatgt cattcatgac
    41761 ccattctgcc cattgttcta aataaggcaa atagcgtgaa tctttcgtgt cttcatacaa
    41821 gtaagccata gtcaatagcg gtgccattgt attgacgttt ttgggcggag cgccttcttc
    41881 catacgatcc tcaaaccatt cattgaccac ttgataagcg cgaggatttt ttgtcatctg
    41941 gtaattttta taaataccat atagaccgac accttgtggc caattccaca ctgtccagct
    42001 tttgtcatct actttcagtc catcaaagtc caacaaaaat tcaccattat cgtctttgat
    42061 cgttgtcagg ttttcaacga gcaggtcaat tttttctttc actaattctt taggtacaaa
    42121 aatctcttct ttaataatca tctttacgcc acctttttaa acgctttcat tttatatcct
    42181 taatatagca gtaataccgt ccactataaa tatcgctttt tgaacaaaaa ctgtctaaaa
    42241 ttgacctaaa tgttaaataa caaaagtaac tttcagttac ttggaaatta aaaaaagaac
    42301 ttggagaaac aacgttttcc aagttctttt tcatctattt tcttatcttt tttctacgct
    42361 ttcttttgct tatccgttgt aagcatcaat gatgatctgt ttcaattcag agatcaatgg
    42421 ttctttcgga ttagctgtcg tacattggtc ttcgtaagct aattcagcca tacggtctac
    42481 ggttgtatct agtgtttctt gtgtgactcc ttgagctttt agactcatgt tgatgccgac
    42541 agattttcct aattcataaa cagccgttgc taaagcttcg actaattcct ctgttgtttc
    42601 gcctttcaga cctaagaatt ttgcgatatc tgcgtaatct gtatctgcac ggaaatagtc
    42661 atatttaggg aacatcgcat gtttttgtgg atcttttgca ttatagcgga taatatgcgg
    42721 taaaagaatc gcatttgtcc gtccatgagg gatcccgtat tccccgccga ttttatgtgc
    42781 gactgagtga caaataccta ggaatgcgtt agcaaacgcc ataccagcca ttgtagaagc
    42841 gttgtgcatt ttttcacgtg attccatatc aggtgttttt actgattttt ctaaatagtc
    42901 aaagactaac ttgattgctt gtaggctcaa tccacgtgta taatctgaag ccatgactga
    42961 aacataggat tcgattgcat gtgttaacac atccatcccg gtatctgctg tgacagatgc
    43021 tggaactgac atgacgaatt gaggatcgac gattgcgaca tctggcgtca atgcataatc
    43081 tgctaacgga tatttcacat gtgtttcact gtcagtgatg accgcaaatg gcgttacttc
    43141 agaaccagtc cctgatgttg tcgggataca tacgaattgt gttttttctg gtttgtcgat
    43201 cttatatgtc cgtttacgga tatccaagaa tttttgtttt gcaccaaaga aagatgtgtc
    43261 tgggtgttca tagaacatcc acattccctt agctgcgtcc attgcagaac cgcctccaag
    43321 agcgattact gtatctggct tgaagtctgc catcagtttc gttcctgcgt atacggtatt
    43381 tgtcgatggg ttcggttcaa catctgagaa gacttcgatc ttcacatcat ttttacgtcg
    43441 tgccaatact tcacgaactg tatcgcagta accgaattgg accataccag ggtcacaaac
    43501 gatcatgaca cgttcaacgt tttccatttt ctctaagtac aatagagagt tcttttcaaa
    43561 gaagattttt ggcggtaatt tgaaccattg catgttattt ctccgtttcg ctacagtttt
    43621 gacattgatt aagtttacag cagagacgtt acgagaaaca gagttcttac cataagaacc
    43681 gcatcccaaa gtcaatgacg gaatcatttc gttatagata tcaccgatgc cgccttctgc
    43741 agatggtgta ttcactaaaa tacgacaagc tttcattcga agaccgaatt tgacatgcaa
    43801 ctcttcgttt tctgaatgga taactgctgt atgtcctaat cctccaagat tcaacatacc
    43861 ttcacacaaa tcaaacgcat ggtccgtgtt gttagctttg atcatggcaa gaactggaga
    43921 aagtttttct cttgatagcg gataatctgg gcctacgcct tccaattcag caatcagcat
    43981 tttcgttcct tttggtacac tgattcctgc caattttgcg atttccatcg cagaatgtcc
    44041 aacgattgat ggattgaccg catattttcc ttcgttcatc actgcatctt ctaatttttg
    44101 caattcatct ggttttacga tataaacttg gtgtgcttgg aattctgctt ttactgctgc
    44161 atagatttct ttatccacga tcacagcttg ttcagaagca caaatcattc cattatcaaa
    44221 tgttttcgaa acgatcaaat cgttcactgc acgtttaatt tttgctgttt tttcaatata
    44281 agctggtacg ttacctggac ctacacctaa agctggtttt cctgtagagt aagcagactt
    44341 gaccattcca gctccacctg tcgctaagac gatcgcgata cctggatggt tcattagcat
    44401 agaagtcgct tcgatcgaag gatgttcgat ccattggata caattttcag gagctccggc
    44461 agcgatagca gcatcacgta ccactcgtgc tgcttctgca gaagattttt gggcacttgg
    44521 atggaaagca aaaacgattg gatttcttgt tttcaacgcg atcattgatt tgaaaatcgt
    44581 tgtggaagtc ggattcgttg ttggagttac tccgcaaacc acaccgactg gttcagcaat
    44641 ttcaatcaac cctttttgga catcttcatt gatcacacca actgttttat catgtttgat
    44701 attatgccaa atatattcgg acgcatacat atttttgatt gctttatctt cgtaaacacc
    44761 gcggcctgtt tcctctacag ccatcttcgc taatggcata tgttgatcca aagctgccat
    44821 tgccatttca tgcacgatat ggtctacttt ttcttgatca aagctttcca tttctttcaa
    44881 tgctgcattt gctttttctg ccaaatcatc aatcattgct tgtacgtcaa ttgtcttcgt
    44941 tttttctttt tctattactt tagccatcat tatcctccta atgggtcatg gttatttgtt
    45001 aaataattca catgtatatc atacaatatt tatttttcta tgtaaacact tttttgtgat
    45061 ttttttcaca gttattttta aatataaaat tgctttattt acaggtgttt gtatagaaaa
    45121 atatataaag ttatttatta ttatttatat gacacacccg attattcaat attgagcaat
    45181 atatcccatg ctcttatctc tttctttttt gaataaaaaa tgaggtagga catctttctg
    45241 ccctacctcg tctttaaata agctttgata cttatttttc ttccttctct tctgtctctt
    45301 ccagcgtttc tgttgtttca gtttttactt caactgtctc agctggttct tctgttgttt
    45361 caacagtagt cgttgcatca tttgttacga cagtccctgg tttgaccgtt ttgattgctg
    45421 cacgatcgta ctcaaggaag atcccttcgc agtctaaaac aactgtccgt ttgtcattgt
    45481 cgatttctga aacaactcca tgtaatccgc cgatcgttac gactgaatca cctggtttca
    45541 tgctatctaa caagttttga cgttcttgct gttgtttctt ttgcgaacgt gacataaaaa
    45601 accacattgc taatagcgcg ataaacatca caagcattgg taatgttccc atttttttca
    45661 cctcactaat tctgtatcta caaaaaacac tttagcagaa aaatgctgat aacactagtt
    45721 ttttacttaa tttttaaaag attttccttt agaagctttt tgcgttttct ttattgaacc
    45781 cgtattcttc aaaaaaggct tctctaaatt caagcaaatt atcatccatg attgcttgac
    45841 gtacttgttt cattagattc aacaagaagt ataaattgtg gtaagaagtc aaacgaatcc
    45901 caaatgtttc atcacatttg atcaaatggc ggatataggc acgtgtatag tttttacatg
    45961 tataacaatc acatttctca tcaattggac ggaaatcatg ggcatatttc gcatttttca
    46021 ctactagacg gccttgagaa gtcatacatg tgccatttcg agcgattcga gtaggcaaga
    46081 cacagtcaaa catgtctact ccacggataa caccatcgat caatgaatca gcagcaccga
    46141 cacccatcaa gtaacgtggt ttgttttcgg ggatcaacgg tgtagtgaat tctaatacac
    46201 gattcatttc tgatttaggt tccccgacag ataacccgcc gattgagtaa ccagggaaat
    46261 ccatcccgac tagatctttc gcgctttgac gacgaagatc ttcaaaccct gctccttgga
    46321 tgattccaaa taatccttga cggtctggat tagcatgagc tttcaatcct cgttctgccc
    46381 atcgagacgt acgttctact gattttttca cgtagtcgta actttcatcg aatggtggac
    46441 attcgtcaaa actcatcatg atatcagagc ccaatttatt ttggatgttg attgcttttt
    46501 ctggtgataa aaacatacgc gaaccgttca agtgattttt gaaatgcacg ccttcttctt
    46561 cgatattccg catatcactt aatgaaaaaa cttgaaagcc gcctgaatct gttaaaatcg
    46621 gttgatccca gttcataaat ttatgcagtc cgccagcttc ttctactaag tcttcaccag
    46681 ggcgtagcca taaatgatat gtattactta aaataacgcc agcacccatt tctttcaact
    46741 cttctgggga cattgttttt actgtagcta atgttcctac tggcatgaac attggtgtgg
    46801 ggaaagttcc gtgtggcgtg atcaattccc ctaaacgcgc gccagtatgt ttttctttct
    46861 tgattaaacg atagcgaatg gcaggttgcg tcattcattt ccctactttc tatataaaat
    46921 atcttgacaa ctcccaccat cataatcgtt tcaagtgctt tttgcaagtt ccctcggctt
    46981 ccttctactt tatttaatat tctttttttt atcctttttt tatgaataac aaaaaaaaga
    47041 aaaacattat gacagaaata ttttttgata catggtatat tggtgttatt aaagaaaagg
    47101 agggaaaaat catgcaatct tctgcagaat taaaacgcca agcaaaagag agtctaaaag
    47161 gacgttgggg acaagctgtt ttactaaatc taatccctac attgattggt attgctacta
    47221 ttcttcttat tatgattcct attatcttgt ttgccaccac catatatgat ggatcagcga
    47281 gcgtctcaga agcgacaact tcaggaggcg gtagttcagg aggcggtggc ggaattattt
    47341 ccagcatcat tagcgctttg ttcatgagcg gtatttcttg gacttatctt gatattttac
    47401 gtggacaaaa agatcagatc gaaccattca aagatgcatt tcgtggattc aaaggtttgt
    47461 ttatcggcgg agtgatcagc ttagctgtgc tgatctcgat ctttacaaca ttatggggtt
    47521 tgctattagt tattcctgga atcattaaaa gctattctta ttctcaaagc tattttattt
    47581 actacgatat cgtccaagaa acaggacaaa cacctaaagt actggatacg atcactgcaa
    47641 gtcgaaaatt gatggatggt tataaaggac aacttttctg gttagatctt tcatttatcg
    47701 gctggcatat cttagcatta gcaactgctg gtattggtta tctatggctc agcccataca
    47761 tttctgcaac aaaagcagca ttttatgaac aattgccaaa agatatttaa aagagagtgt
    47821 gacttgtgac cgagggggtg gcaggagaac accgtttatc gagaggcagt aaaagaaaca
    47881 ttcagcccat tagcaaaaag gaggtgtgac aacattcatg tcacacctcc tttttgtata
    47941 gttccagtaa aaagaaaatc aacttagaaa cagttaatca ttcctcttct tctgcttccg
    48001 gtaatcgatg gaacttgatc agttcattca ccgcgattgg tacgatagat aaaatcccta
    48061 ccaagaacca gtgattcaaa ctgatgtgta ctaggccgaa tagttcttgc gtaaatggca
    48121 gcaaagcaac agccgttgta atagctaatg ccagtaacgc catttctacc aaagctttat
    48181 tggtcgctaa attgactttg aagatcgatt ggctgctgcg tacattgaac acatgcagaa
    48241 tcgatgaata agctaagatc aagaatgcaa cagtttgacc gacatgctga cttgcgtcta
    48301 cccatgggct gatagtatcg acataactac ctaaataata accaaacaag gttacgatgg
    48361 tgaagacccc tgcatttatg gcaatttttt gcaataaacc tcgagcaaag atcccttcat
    48421 ttttcggaat gggtggctga tccatgatgc cgtgttccgc tggctctctt cctaaagcaa
    48481 atcctggaag tccatcagca actacattga caaacagtag ttgcacagct gtaaatggtg
    48541 ctccccatcc taacagcatc gcaatcaaaa caataaagat ctccgaaata ttacagctta
    48601 gcaaaaagtt gatagcttta cgaatattct gataaaccga acgtccttga ctgacagcgt
    48661 ctacgatcgt cgcaaagttg tcatccgtca aaatcatatc tgcggcactt tgcgccacat
    48721 ctgttcctgt gatccccatg gcacacccaa cgttacttgc tttcaacgct ggtgcatcat
    48781 tcacaccatc cccagtcatc gctacgactg cacccgtacg ttgccaagat ttgacgatcc
    48841 ggatcttgtc ttctggcgtt acccgagcat agacagagag agctttgaca cgcgcatcta
    48901 attcttcgtc tgataattga tgcagttctg atcctgaaag tgcttctgac ggatcattca
    48961 agatacctaa ttctttcgct atggcactgg cagtcaccac atgatctcca gtgatcatga
    49021 ctgttttgat gccagccttt ttcgctcgct tgattgctcc tttactttct ggacgtggtg
    49081 gatcgatcat tccgatcaga ccaatcaaac gtaagtcttt ttccagtgct tcagaagaaa
    49141 tatcttgcgg ttcttcgtca taagtagcat aaccaacagc aatcactctc agtgcccgtt
    49201 taccaaagcg atcattaacg atcgccgctt gttctacatc gcctgaacta aagcgcggag
    49261 caagaacatc gaatgctcct ttggtgattg agatgtattt ttcgcccatt tggtgaactg
    49321 ttgtcatcat ttttcgttca gaatcaaaag gaagctcgtt tactcgtgga tatttttctt
    49381 ctaattctgc ctttgtatga taattctctt caacagccct tacgatggct acttctgttg
    49441 gattaccttt gataacaagg tcgtcatctt cttgctcgac cgtcacatct gtacatagtg
    49501 cagccatttt caatatttcc atcgcgctgt tcgtcattga atcttcgata ttcgttactt
    49561 catcttcttt gctccatacc cggcggacgc gcatttcatt ttgtgtcagc gttcctgttt
    49621 tgtctgagca gataacatta gcggttccta gcgtttcaac tgctggcaac tgtcggatga
    49681 tcgcatgttt cctcgccatc ttctgcacac cgtatgcaag tgtcaacgta acaataacag
    49741 tcaaggtttc cggtacagct gcaacagcca aggaaatcga agtcatgaac atctcaagga
    49801 gtggttctcc ttgcagttca ccaatcacaa atactaaagc cgcagccgct aaagcgatca
    49861 tactgattcg tttgcctagc tgattcaatc ggacctgtaa aggtgttttt tgcatagtat
    49921 tttcgttcaa aagatccgcg atcttaccca tttctgtagc catgccaatg gcagtgacga
    49981 tcgctttccc acgacctgca gcaaccgtac atcctttaaa taccatatta agttggtcac
    50041 ctaatgactc atcttcttca gcaataaatg ctgcatcttt ttcaactgct tcactttctc
    50101 cagtcaacgc cgattcttct acacgtaatt gtgatgcttc gatcaaacgg gcatcggcag
    50161 aaatagcatc accggactct aaaacaagaa tatcacccac taccagttgc tctgactcaa
    50221 cagtggtcac tttgccgtct cgtatgacag ttgccgtttg tttattcata tcttgcaagg
    50281 attccagtgc tttttctgcg tttccttctt ggacaatcgc caataccgag ttgatcacaa
    50341 cgatagcgat gatcagcagt ccttcaaata aatccccatg ttctgtagca aatgcggtat
    50401 aaaaggaaat caccgctgct acaagaagga tgatcgttgt aaaatcggac aagcttcgaa
    50461 agaatttttt gatcatcgat tctttcggcg cctcatcgaa tttattcaat ccctgctttt
    50521 ttcgccgttc atccacttct tgtgaagaca acccagtatc tggatctgct tctgttacct
    50581 tctttacttc ttctattgtc tgcttgtatt cttccatcct attcctcctt taaaatcttc
    50641 gtacaaaaaa aggtacttat tttactataa catccttttt ttatttactt caaataaagg
    50701 gcttatcgat tatttgttaa gaaagcgtaa aatttaaagt gcttatattt gcaaacgcta
    50761 ccaaaggatg ctattatata gatgtaagga aggaggatac catcaaatag acagaagaat
    50821 ttctcgatag aacagtgtaa gcaaacaaag ttgttagaag tacaggtttc acccagacat
    50881 gcgtgtagag tacaaaccta taaatagtga atgcgtatgg atgtttggat cacgaagtat
    50941 ccgaaacaag aagtaatgcg atacgtaaca attgaataac gtaaacgtct gaaaattgaa
    51001 taggaacaag agatgtttca aatgttgaag atgtaacgaa aacaaaattt ttgtttaaca
    51061 tgaagaaatt caacaccgtg ctttgcatgt atgatggaaa gttacaatca tttctgttta
    51121 tttgaatcct tccgaggtac aagaaagccg agcttatcga gagctcggct ttttctttgt
    51181 cataaaatct ttgtaaagct tttttgttat tcaaaactag cggcttttca taaccttatt
    51241 tcacgaacat cgcatctcca aaactaaaga aacgatagcg ctcttcaatc gcatgctggt
    51301 aagcagataa agtcaattct cttcctgcaa aggcactaac taacatgact aaagtcgatt
    51361 ttggcaaatg gaaattagtt gagaaagctt ctaccacttt gaattcatag ccaggcgtaa
    51421 tgaaaatatc agtccatccg ctgtctgctt tgatttctcc attaaatttc gttccaatcg
    51481 tttctaatgt tcgaattgaa gttgttccga cagccacgat tttcccgcca tttttacgta
    51541 cttggttcaa tcgctcagcc gcttcttccg tcaaacggta gaattcacta tgcatatggt
    51601 gttcttcaat tttatctacg ctgacaggtc ggaatgtacc taaccctaca tgtagtgtca
    51661 gatagactaa ttcaacaccc tttgcttcga tctcatcaag taattctttc gtaaaatgca
    51721 atccagctgt tggcgctgca gcagaaccat tttctttcgc atagacagtt tgatagcgat
    51781 ctgggtcttc cagacgttct ttgatatatg gaggcaatgg catttctccc aatgattcaa
    51841 gaatctctag aaaaattcct tcatactcaa agtcaatgat ccgtccgccg tgttccaatt
    51901 cttctttcac tactgcttgc aatctgccat caccaaaaga gattcttgtc ccaactttgg
    51961 cacgtttcgc aggtttgatc aatgtctccc acgtatctcc ttgtgtattc gttagaagaa
    52021 ggacttctaa atgcgcacca gtatctggtt tttctccata taaacgagca ggcagaactc
    52081 gtgtattatt cataactagc gcatcaccag gctgtaactc ttcaatgatt tcatggaaat
    52141 gtttatcttc catctctcca gttttccgat ccaaaacaag taaacgagaa tgatcgcggt
    52201 cttttaatgg tgtttgtgcg attaattctt ccggcaagtc aaaatcaaaa tcttctgttg
    52261 ttaacatatc gtcactcact ttctatcatg tgcttcatca ttctatcatg tttttcgttc
    52321 tgttggcaaa atcagcactt tttcacttct attttttgtt ttcctaaata aaaaaactac
    52381 cctatttgta ttttttcatt gttttaggca tactagtaat agatagttct tcattgaaaa
    52441 tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg tcaaaaattt ataaaggtgg
    52501 aaaagtcgct gtagaggacg tcaatctttc atttgaaaag ggtgagttca tttgttttat
    52561 cggtacgagc ggaagcggaa aaacgacgac gatgcggatg atcaaccgaa tgactgatcc
    52621 aacacaaggg aaaattttga ttgatggaaa atccatccaa gaaattgatc cagtggaatt
    52681 gcgacgtcag atcggctatg ttatccaaag tattggattg atgcctcaca tgacgatccg
    52741 tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt caagaagaac ggaataaaac
    52801 agctgaaaaa atgattgatc ttgtggaatt gccccgtgag atgttagatc gctacccaca
    52861 tgaattatct ggtggtcagc agcagcgtat tggagtcgtt cgtgcccttg cagcgaatca
    52921 agatatcatc ttgatggacg agccattcgg tgcgcttgat ccaatcactc gtgattcctt
    52981 gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa acgatcgtat ttgtaaccca
    53041 tgacatggat gaagcgatta aactagcaag ccgtatcgcc atcatgagtg aaggccgtgt
    53101 gatccaattt gatacaccag aaaatatttt acgtcatcct gcaaacgatt tcgtagaaga
    53161 gttgattgga gaagatcgcc tactacaagc caagccaaat gcgacaagag tcggcgaagt
    53221 tatgctaaat acagcaatca cgattacacc ggaaaaatca ttacaagaag caatcaaact
    53281 gatgagggaa aaacgtgtag atacgttgtt agttaccgat aattcgaatg tattaaaagg
    53341 atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa gtatccagtg tcggcgacat
    53401 tttgaataaa catgtttttt acgtaaaaga atccgcctat cttcgtgata ccttgcaacg
    53461 cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat gaacagaaca aagtcgtagg
    53521 tatcctgact cgtgcatcat tagtggatat cgtctacgat gtgatttggg gagaagatcc
    53581 cgcaactact gatgttgcag agtcagctac tcctgaagaa tctaaggagg tctgacctat
    53641 gcagcagttt tttcatcagc acggttcaga aattctctca aaaggttttg aacatcttta
    53701 tatttcagga cttgctttga tcattggtat catcattgct gtaccgcttg gtgtcttact
    53761 gacacgtttt ccaaaagctg ccacgattgt gattggctta accagtgcct tgcagacaat
    53821 cccttctctt gctttattgg cattgatgat cccgctattt ggcgtaggta aattacctgc
    53881 gattatcgca ctctttattt attcattatt gccgatttta cgtaatacgt acattgggat
    53941 gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc atggggatga ctgagttcca
    54001 atccattttt tccgttgaat tgcccattgc tatgccaacg atcatggctg gtattcgttt
    54061 agctgccgtt tacgtgattg catgggctac acttgcctct tatatcggcg ctggtggttt
    54121 aggcgatttg atttttagtg gactgaataa ttaccaacca gatctcattt tggcaggtac
    54181 gatccctgta acaattttag cactattggc tgattggctt ctaggtctct tggaacaccg
    54241 gctgacaccg atcgcactta gagaggagaa tgaagaatga aacgtatact aaaaatgacc
    54301 atggttcttt tctctcttct tatacttgcg agttgttcct tccctggtct tgccagcaat
    54361 acagatgaag acaccatttc gatcacaggt ggaatcactt cagaagcaca gatcttagca
    54421 agtctagttg ccggaatggt tgaacattat acagataaaa ataccgcaat catcaacaat
    54481 ctggctacta caactatcaa ccatcaagcg atgatgaacg gagatgcttc aatttcagcg
    54541 gctcgctaca caggaacaga tttaacgact acattgaacc ttcctcctga aaaagatccg
    54601 aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa gatacggtca aacgtggttc
    54661 ccgtcctata gttttgaaaa tacgtatgtc tttcttgttc gaaaagacac cgcacaaaaa
    54721 taccatctat ctaaagtcag cgatctgaaa aatgtagcgg atgaattagt agctggtgta
    54781 gatacttctt ggatcaatcg taaaggagac ggttatgacg gcttccaaga aacttatggc
    54841 ttctccttca attcgatatt acctatgcag attggacttg tttatgacgc agtcgaagca
    54901 ggaaaaatgg atattgttct tggctactct acggatggac ggatcgccag ttatgatcta
    54961 gtcatgttgg aagatgatcg tcaattcttc ccaccatatg atgctgctcc agttgtagac
    55021 aacaagatat tagctgatac gcctcattta aaagaagcct taaataagtt aggtcatacc
    55081 atcagtacgg aaaaaatgca ggaattgaac tacgaagcag ataataatct agtggaacca
    55141 tcagtagtag cacaacgttt cttacaagaa aaccactatt ttgaagggaa gtgaagcaat
    55201 tggataaaat gaatgtcttt caacaatttt tctattattt ccaggaaaat ggctcctata
    55261 tctttgcaca atttatccgt cacttcctga tttctatcta tggtgtcctc tttgcagcag
    55321 ttgtcgggat tccggttggg atcatgattt ctaggagacg taaattagca aactgggtga
    55381 ttcgtttggc gaatatcatc cagacgatcc cttctctagc catgatctcc attttaatca
    55441 ttggattagg cctgggagtc aatgtcgtga ttgttactgt atttttgtat tccctcttac
    55501 cgatcatcaa gaatacgtat accgggatga tccaagtaga caaaaacatc cttgatgtcg
    55561 gcaaaggcat ggggatgact gctagacaac gactattcat ggtagagtta ccactctctg
    55621 tttctgttat catggcaggc ataagaaacg cgttagttgt tgccatcggg ataaccgcga
    55681 tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat tatccgagga accaatgcaa
    55741 cagagggcac atcgattatt ttagcaggtg cattgccaac tgcattaatg gcgatcatca
    55801 cggactggct tttaggtatt ttggaaagac ggctagatcc agccagccgt acatcacgct
    55861 gatgttattg taaaaaacaa aagcttctgc gaccatttgt tggtcgcaaa ggctttttta
    55921 gttctgtcat ttttaaggca ataatccact ctgattcttc cctccttatg ggcaaagagt
    55981 tgcttttctt agctatttat ccattccgta tactccaact tcatactgcc aacgggttca
    56041 tatctgcatc caccgactaa gtttttttct tatccgctaa ggcattttgc caatccattt
    56101 tcccatcact cgtcatggaa ttcataccac atgatctcta aatactcgtc tgcttgttct
    56161 ttgaattggg catcaattct tacatccttt ggcgtggctt tcatttaagc cttttccatc
    56221 agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa ctggtgactg ccgtatcggt
    56281 aacttcgatc atcttttata caatcgggaa cttgccatcc tcatccttgg ctaaaaacat
    56341 atctagccat tccagcttct cgccatggga ggtttgcggt tcctaaaacc ggtacacgat
    56401 tcttatggac tgcatccgtc gcaactagac ttggcgatac gatgatcctt caccagaaga
    56461 gcacccccgt aaaccaattg atcgatatat tgccaataag aaaagacatt ggcgtaaaag
    56521 atatcgatcc ctcgtgatgc attgccgttg atactgctat tcatggccga aagcgccacg
    56581 actttaactt cttccgtttg agtgacattc atgttcggca atgtcgcttt ggatacccgc
    56641 tctgctaaag gaacgacact ggtattgtat ttcgtatctg tatcttttcc aaaagaccat
    56701 gccaacgaat cctctgggaa ccaataagac gactccggtt gattgtccat tgcttttttc
    56761 aacatacttt tggctgtttc tcgataaacg acatttccaa ttgtcttcgc ctcactttgg
    56821 cgataatcga tggtcgttgc cactgccaac actaacaacg atgctccaat tttactgatt
    56881 ttccttgtca cacttcttcc tccttgtttt acataaaccc gtcaacattc cattcctaaa
    56941 ctcaaacaat gacccttcaa aggtggagat ataggaacaa attaaagaaa tcatgcaata
    57001 aatccaagaa ggttggtttt agaacaaaaa aagagtctcc tttttgggga gactctttgt
    57061 taactatcta aaaaggttgg ctcttctcac ttcactcata atgtgtccag gcagaataaa
    57121 tttctacaac tttattttcc tcatcaactt tgtaaaccac tcgatgctgt ctattcagcc
    57181 tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc aaaagactgc gtgggcatat
    57241 atggatcttc cttcaatgtc tgaatcactt cttcaaattg tttctttaaa ttcgtttgct
    57301 tgatttttct taaatccact ttcgcagagt ttttgattgc gactgtatag ttactcatca
    57361 aagagcttcc caatcaatat catcgatatt cgtaaagcta ctgtcgtctt tttcgcggtc
    57421 tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg gtttcttgaa tcgctctcca
    57481 gtcttccagc ccaatcaata cagcattgtt tccactacga tcactaataa tctcgatttc
    57541 agtatgattt tcatttacct ctttcaataa ctgataaaaa tttttacgag cagtgctagg
    57601 attcatcgtt gtattagcca ttgtctctcc tcctttttct gatataatta tagcgtactt
    57661 gattaagtac gtcaaaaaaa tacaataaag cacttaaatt cagcaaactt ttcctctttt
    57721 ttacatagag aaaaagaccc ctttttaggg aggatctttg tccacgctca cttcttactc
    57781 ctttacgact agcggtagcc aaacgtaaag taattggtaa caacgtatca tctttagcaa
    57841 aggtcgaatc caaagcctgt gagtctatgc aacaacacca atacacgaag gttcctcgtt
    57901 gcagtgtgac ttgattgata tcttgaataa cctgaggata cgcacgaaag atttgtaacg
    57961 gttattcaaa actgattttg gccgtcaagt cttctactgc ctcaaaaatg attgcctctt
    58021 tcgtctcctg tcattcatgt tcactatcga tttgatactt gcttagaccg ttgggtttgt
    58081 gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa aaatggtcac ttgacgaggc
    58141 tgagattcct acttatgaag acacatggca cttaagagtc gaggtaaagg aagaagctga
    58201 aaatatagga ggctgtacat tatttggcaa aggattcgga aattatgatc aagacatcaa
    58261 aatcaaaatg ttttacagct aaataggaag aataataaca tttcatacgc tgttcccatc
    58321 tttaatggct tatagagggc acctttagct gagaataaga caaaacagac cctctagctt
    58381 caattaagag ctagagggtc tgtttttgat tttaaaactt ggtttatttc ttcaaatggt
    58441 agctataggt gctgacaacg atattttcac gccaagacaa tcgcaatctt aaccgcaaac
    58501 ttgtttggtt atggagaata ttctgccagc gtctgtttgg tacaaattga ggaatcaaca
    58561 cagtagttgt atagttttgt ttcgctgcat ttttacttac gatatctaca taacggataa
    58621 ttggattttc aatcgagcga taagaagagt ggacgattga aaaacggaca tctgggaaat
    58681 gctttttaaa ttctgcttcg atttcttttt ctttttcgac atcttcgtct agcgaaacat
    58741 gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt caacgcaccg atatttaccc
    58801 gtgtcacatt cccgactaat acaagaacgg tattcccgtc ataatcatgt agttttgcat
    58861 cattttctaa acgaagctgt tctgctactt ttttataatg atcatggatc ttataaaaaa
    58921 tgaacataac gattggcata atgatgaaga aaggccaaat gtcccctaac cgatagacaa
    58981 acaaaatcgc aatgattgca tatgagatga acgcacccgt aatattggca atcgatttgc
    59041 ttaaccatct ttttccttct tttttccatt tgacgaccat ccctgtttga gataaagcaa
    59101 atggaatgaa cacgccgata gagtataacg gaatcaagcg ttctgttgag ccatggaaaa
    59161 taaacagcaa tacgatcgaa cctagcgcta gtgtgataat cccattggaa tagcctagtc
    59221 gatccccacg atcttgatac atgtgaggca tgaatttatc ttttgccaga ttgtatgcaa
    59281 gaactggaaa agcagaaaaa ccggtgttag cagcaactgc taaaatcagc gctgtagcaa
    59341 attgaaggac gtaatacaaa ataccatgtc caaagacagc tttaccaatt tgagacaaaa
    59401 cagtgacttc tttttcagga acgatcccat accaatagtt gataaatgtg atccccacga
    59461 agaagaaacc taagatcaat gccatcatcg tcaatgtagc agcggcattt tttgctcttg
    59521 gcttcttaaa gaatggtaca gcattactaa tcgcctccac cccagttaaa gaggaagaac
    59581 cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc cggcacagcc gctcctggaa
    59641 gtgcagtagc ttgcaatggc acagcacctg tcacgatatt atataaacca acaacgatca
    59701 gtaacgagat cacaaggata aatgtgtaca ccggaaataa taggaacgat gcagattccc
    59761 tcagcccacg aagattcagc atcatcagta gcaaaacgat tgtcacagaa atagcgactt
    59821 gatgaccgta gagtgctggc accgctgatg tgatcgcttc agcacctgct gagacagata
    59881 ctgctactgt caacatgtag tcgatcaata aagagccacc ggaaatcaag ccagcattct
    59941 ttccaagatt ctcactgctg acgacatatg ctcccccgcc atgaggataa gcatggatga
    60001 tttgacgata tgatagcgtt aatgaaatca ataaaataat aacaaaagcg gcaatgggta
    60061 gcgaatacca gatggctgca gcagacaaag cgactaaaac gacaacgatt tgttccgtac
    60121 catatgcaat agatgataac gcatcagacg acaataatgc caaagcagca aatcgggtta
    60181 atttgtgctc atcattttca gcagatttta aaggcttacc tactaacaac ctttttaagt
    60241 aatccaattt ctaaactcct ttacacacaa ttttacttca agttttatag tcgaaaattt
    60301 atagtaaaca agatgttata gtacgctcac tgaccttaaa agtcaataaa ctttaagaaa
    60361 ataattggaa aaaaacagaa aaatatcaag cgctttttca aacgctttaa tacagcaaaa
    60421 atctaacatt tttttatggg ctttttcttt gaattctata ataaaaggat agaacttgac
    60481 ttagaaaatc aagttctatc ctttttgata tcttaacttt tggaagagag atgtaaggct
    60541 gctttctacc catcattctt actactcgaa gcatagcgca gttgtcacaa cctcttgata
    60601 aacggtgttt aaaagcttgc atctgcggta ataagcccaa ccaaattaaa aacataagaa
    60661 gctgttttta tttggtcgtt cttattactt gatgcagagc agctttttta caacctcttg
    60721 gtacacggtg ttcaatcagc tgaccctcgg tattagctca aaaaaacggc aaaatatgag
    60781 gaactatttt tccatttttt tctctaatac tcaggtcaaa acactgattt cacaacctct
    60841 ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt gaatttcgtc attttttctt
    60901 cgatgaacgg atagattgcc gttcctacga ttccaaagac aacaaacaaa ccgatcatga
    60961 tccagattgc tttcgtagca tttggccaat aaattcctcc tgcagattcc cgtaacaagt
    61021 ttaccgcatg agtaaatggc aagaacggat tgatcatttg gaagaatttc cctgagactt
    61081 ggatcggata gttcccgcct ccgccagaga tcgacagtac taagatgata atagcgatcc
    61141 ctttaccgac attatcgaat aatgcagcca agacatagac gatcatcatg aacgctaagg
    61201 cgatcaagac agcaaatgac acgctgtaga ccggattttg gacatctact cctagtaaga
    61261 aaatattccc taatgtaacg atcaagcttt gcgcaatcgc cattgtcaaa aatgtcagca
    61321 tacgagcaac gaattgttct cgtttcgtaa aattgtttcg gtctttcttt cctaaatagt
    61381 attctgtcgt agcaacactt gaaagaagaa cagcgccgac ccacagacat agtgcagtat
    61441 aaaacggggt gctagctgaa ccgttatttg cgattggata aagcgcattg gtttgtagct
    61501 caacaggttg tgtaaagaag tcactttctt ttgttgcgtc tagtttcaat aatttgatga
    61561 cttcgcctag atcgacttct tgttcgcctt ttcggatcgc gtctgctgct ttttggatac
    61621 cagctttgat atttggccag tcattgttga tcaagtccgc agcagcgttc acagctgttt
    61681 cgacttctgg cattttttca tttactgttg tcaatgtacc ggtgatttca ttttttagtg
    61741 ctggccaatc attttggata aaatcagcgg ccaatcctaa tttttgctga atgatcggta
    61801 attcattgtt gtataggtct gccccttcat tgatgccatt gacgatggta tccatatttc
    61861 cattcagcat tgtattggca tcatggattt cttgtccaat tgcaggcatt tctttttgat
    61921 atttttctaa aattgccact gcattcgtta cagttgcttt cgttgagctg agaagcgaat
    61981 caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc agtcccaatc gtatcgatga
    62041 cttggtctag tagagaagtg acagtggaac tgatttgacc tgtattgata ccagcaatga
    62101 tgccattgat attattaaca acggcatcaa tttgatctag caattcatca atagccttcg
    62161 tgtcttcatt ttgaacagct gtgttcaaag cagataggcg gttttgcaga ttgcttagca
    62221 agggttttaa ttgatttagc tgatcaataa ttggctgtaa tttcgtattt ccagcacttg
    62281 tttgcaattt agtcaggaac tcgaccagtt tatcgattgc attttgttgt tgagatattc
    62341 cgtcaataaa gccgttcaat acattgctga tgtttttctt ttcatcatca gtcagcttac
    62401 catcttcaat agctgttctt acagtatcta ttaacgaacc tgtcgttgtt gccacttgtc
    62461 caattgactt caatgtaaca tctacactgt ttgtgatgct tggtatcgca tctttcagct
    62521 gagaggcacc tgattttgtt tggtttgcta gatcacttgc ctgattttct aaatttttca
    62581 catctggcaa gatatcttgt acttgttgga tgatcgtcaa gccttgtttt gcttcatcga
    62641 ttccttggtt cattgtctct tggatcgaag caaaatcgcc gtcgatctct gctagttgct
    62701 taccggcatt ttggatctct gggatttttt cttgcaaatc aaggatgatt tttgcttgat
    62761 ctttcaactc aggcattttg tcattcaatg caacgacttt ttcacccatc tcatctactt
    62821 tagggatgta atccacgaat tcatttgctt tattcagttt ttccttgatt tcaggtagtt
    62881 gactttgtaa ttcgaggact tgttttgtgt agccgtcgat cgtgtccaaa ttttcatctg
    62941 ttgataaaat catatcttta actttattga tacttactag gttcgtatcg atgtcgtaac
    63001 ctatctcatt gaatactttc aataaagtcg aactggctgt tttgataaat tcatttgtga
    63061 tttgcgattg gatcgaactt gctcctttat cggtgatttt cggtgcaatc gcattgattt
    63121 tttcatttac cgtatattcg atttttggtt tcttgatatc accactagta aaactcagca
    63181 gatcttctga gaaatccttt ggcaagtaaa tacctgcgta atactttccg gaacggactc
    63241 cgtcttctaa ttgttctttt gaatcaacga attgccatcc taattgttta tttttatgaa
    63301 gcgattcgat gacttgctcc ccaatggcca cttctttacc ttgaaactct gctggcttgt
    63361 ctgcactgta aacagcaatt ggcagctctc cagtatttcc atatggatcc cataatgctt
    63421 tgatgttaaa ccacgcatat agcgaaggga tgatcatgat cgcgatgatc agaagtgttg
    63481 caatcgggtt tttgaaaatc cgtttccagt caagcaaata taatcgaagc gtatttttga
    63541 ttgactgcat agttctcccc cttcttcttt tttcagctga attactttac catgtatttc
    63601 atactttttt caatcggctt ttttcaaaaa agtcgaattt ttggacatat cacggcaatt
    63661 gtctcattgt aatctcttac atattgagaa ataattaagg attacagcct ttactttatc
    63721 atgaaataaa agggaaagat aattttatgc caaagttttt atctattata cgtatacgca
    63781 aaaaagctaa aacatttttt gtctttgccc ctacaaaaat gtttcagctt ttttcgtttt
    63841 ttattcctgt atttcttatt tttcgaatga caggatgatt ttcccagcag gaggatgtcc
    63901 ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa gcagacagat tcattgaaat
    63961 aaaaacatga aaggctcctt tttggtaggc tttgattatg ccagcaaagg cttctgcatc
    64021 tagatattcc tttcttggaa caaacgattc ataaaagcct tccttttttt gccgcaaatc
    64081 tagatctggg aggtcattta atgcaacata cctgccgcct ggtttcatga tctggatgcc
    64141 ggtttctcct ttgatacttc ctttcgtcgc atcgattaca aggtctgcct gatcagcaaa
    64201 ttgcagacct ggatttgttt tatcataagc agcaaatgct gaagctccta atttttttac
    64261 cttttcctca tttttactgg atgcactggt taagattcgg attccctttt catggagaag
    64321 ctggatcaga cttgacccga ccgcacctga tgctcctagt atcattacag tatctgtcgg
    64381 ctggatttcc gtcaaatggt tgattagatt ataagccgta attcctggcg tgaccattcc
    64441 ggctgcttct tcccaactca ttttatctgg aatttttgct acttttgctg atggcaacac
    64501 gacttcttct ccgtaagtcc cgccgactgc atggacagct actcgatcac ctacatgaac
    64561 agttgtgaca tctgaaccaa tctctgtcac aataccagcg ccatcattac ctggtacata
    64621 agggaatttc aatgttcgta tctctttcat ttctcctaaa cgcaaggcaa catcataagg
    64681 attcacactg aatgctttta tttctacacg aacatgtcca gaaccgactt ctctgggatg
    64741 agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa ccgttaattg caaatcttcg
    64801 catggtcacc atctcccttt ttctttaagt ttacgtttat gcctttattt tgacaaaaaa
    64861 aatgtctttt cgttttggcg catgattcaa aacaaaatag ttgtcttttt tcgcgtaacg
    64921 tgttaaatta tttatctaaa agcgtaaaga ttacgattta cgctaataaa aaataattgg
    64981 aggaatttgt tgatggctaa aaaatcaaag attgccaaag caaaaaaaca gcaagaaacg
    65041 attgaacgct atgctgcttt acgccaggaa ttaaaagcgc aaaaagatta cgaaggcttg
    65101 cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa atcgtgattt aatcgatgga
    65161 cgccctcgcg gatacatgcg taaattcggg atgtcccgta taaaattccg tgaattagca
    65221 cataaaggtt tgattccagg agtaaaaaaa gccagctggt aatccaagtc tggctgtaat
    65281 gtaaaggagg agggcgcatg gaccactcct tggatcatca aaaaagatac gttcgcttct
    65341 tctagcagaa atgctggtac tagaagcaga cgtatctttt tttacgcaca gctggtcctt
    65401 ttttatatgt aaaggctgca tggttacttc gctatattta tttagtaaca ggagtcagtg
    65461 cttcgatacc cacactaatt ttcaatgctc ggtcaacttc tgccataatg ggtcgatcca
    65521 aatggcagac cttttctttc aatcttgatt tatcgatcgt tctgatctgc tccaacagga
    65581 taacggagtc tctttctatt cctgttccag tagctttgat cccaatgtga gtcggaagct
    65641 taggtttagc catttttgcc gttatggccg caacaatgat cgtcgggcta aaatggttac
    65701 ctagattatt ttgaataacc aaaactgggc gtgttccgcc ttgctccgat cccacgactg
    65761 gagaaagatc agcaaaataa atatctcctc tttttaccat aggatcctcc ttattcttga
    65821 tattctcttg gtatccgctg tcctaatccg caagccactt catagtggat cgtacctaat
    65881 tgatctgcta tatcctgcat agtgatttct ttgtctgcat ttttgccgat aagcgtcact
    65941 tttgttccga caggaaattc ttgaggcaat cggatcatca gttgatccat acatacacgc
    66001 ccaatcgttt cacagtagtt cccttctacc aatagagaaa aaccctgcat ctttcgtggc
    66061 cagccatctg cataaccgat cggtatcgtt ccgatccact ctgcttcagg agtgatatat
    66121 gtttctccat agccgattcc ttcacctgct gggagttttt tgacttgaat caattcagaa
    66181 accagctcaa gtgctggctg caatggataa acttccggta gtgcgtgccc agagggatta
    66241 agtccgtaca ttgctactcc ataacgaatc atattgccga ttgtttcatc atgccataaa
    66301 gccgttgcac tattgctgac atgtacatat cgaggaagtt cgggaagttt tttcagcact
    66361 tctataaagc gttctttttg cagattccaa tatgtatcat ctgcctgatc tgctgtagaa
    66421 aaatgggtaa ataaaccttc ccattctaat acacgacttt ctttgatgaa tgcagctgcc
    66481 tcttttactt cttcaggtgt acaaaatccg atacgaccca tcccagtgtc tgcttttaga
    66541 tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa cagcagctgc tgcttgcaac
    66601 cattcccgtg tacctgcagt tactgataaa tcatgagcaa cagctacagt cagtgcgtcg
    66661 taaggaacca tattcaagat aaggatgggc tgagtaaatc cagcttctct caactcgact
    66721 ccttcatcta aatttgaaac acaaaagccc gaagctccac ctgcaactgc tgcctcagct
    66781 gtttcaatag ctccatgacc gtatccgttc gcttttacta ctgcaaacaa ttcttttcct
    66841 tgcggaagtc ttgcaacttc atttgctaca ttttcagtta tagctttttt atgtatcact
    66901 gctttcgttg ggcggtgcca agcgacaacc atcgtttttc cttctttcta gtcttccaaa
    66961 ataatttgtg caaaagctgt ttcatttgta tgagtaatac tgacccatac attgccttca
    67021 tgaggtgaac gcgtcacaac aggctgacca ttttcatttt ttaaaatctc gacatcttga
    67081 aaggtaactt ttccgatccc agttccccaa gctttagaga aagcctcttt gcaagcgtaa
    67141 cgcccgccta aaaattctac ttggcgatga aaaggcaagg actggaatag tttcatttca
    67201 tcagaggtca agattcgtgc aatgaatttt ggtttttctt cgatcagccg agtgatccta
    67261 ggaagttcga ctgcatcgat cccaattcct tttatcatat gcttttctct tttcaataaa
    67321 tttagaacac tctcattcta ccaaattata accattttgc cacaaataag tccacaaata
    67381 acaaaaatga aagtttctct taaaaaagag aaactttcat tttatgttta atcgttattt
    67441 gaacggatta caaatccgcg ttttttatca ttgtgacgtt taccgccatc tttttggctg
    67501 ttattatttt tgctataacc gccttttgat ttgtttccac gataattacc gccgtcacga
    67561 cgattacggt tgtttccgcc accacgtttg ccatttttat tgtatccttt tttctgcatt
    67621 ggcaatgggc gttctggtgt gatcttcact ggcactgcat cagctggatc ttttgctgtc
    67681 gtttttagca aaagtgcaac taaatcttgt gcagaatatt cttctaataa tttatctgct
    67741 gtttgcaggt atttatctag accattttct gcaagttttg tttcgatttg ttcaactgca
    67801 gcacctaatt gacctttgaa tgcttctttt tcggttggtg gacgtaaagt cgtcatccgt
    67861 tttttcgtca agttttcaat cacatgcaag tagtccattt catttggtgt aacgaaagtc
    67921 acagacatac cgccttttcc ggcacggcct gtacgtccga tacggtgaac gtagctttct
    67981 ggatcttgag ggatatcata gttgtacaca tgagtgacac ctgaaatatc taatccacgt
    68041 gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc tcttaaatga acgcaatacg
    68101 ctcattcgtt tttgttgaga caaatcgcca tggattcctt ctgcacggta accgcgtgct
    68161 tctaatccgc gtgccaattc gtctacacgg cgttttgtac gtccgaagac gattgttaat
    68221 tcaggtgttt gaacatcaaa caagcgagtc atgatatcga atttttcgta ttcttttgcg
    68281 cggacatagt attgatcgat caagtcagct gtcatttctt tcgctttgat cttcacatga
    68341 tgtggatttt tcatgaattt aacgccaata ttcttgatag ctggcggcat cgttgctgag
    68401 aaaagtaatg tttgtctttg atcaggaact tgtgaaatga ttttttcgat atcttccaag
    68461 aagcccatat tcaacatttc atctgcttca tccaaaacta atgtttgaac ggttccaagt
    68521 ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg gtgtacccac aacgatatgt
    68581 ggacgatctt tcaagccacg gatctgacgg ccaatatctg ctccgccgta aacggcttgt
    68641 acacgtactt ttttgtcgcg ccctaaacga tataattctt cttgtgtttg gatagctaat
    68701 tcacgtgttg gtgcgataac taaaccttgt aattcgtgac gatctggatc gattttttct
    68761 aacattggta atccaaatgc agctgttttc cctgtacctg tctgtgcttg tccaataacg
    68821 tcttttccag ctaatgctag tggaatcgtt tctgcttgga taggcgttgc ttcttcaaaa
    68881 ccagcgcgtt cgactgattt caacaattct ggtgataatt ctagttcttt aaatttcaaa
    68941 tgaatcctcc tatatggttg ttaactgagg atgtagcttt tttgctaccc cgtcgatttg
    69001 ttcggtcaaa gtgtattgtt tctttttgac agtggccacg cacgttttta tccattctta
    69061 gcccctgtgg caccaccgaa aaatcacttt gcgaagttta ggcattagaa aagccaaacg
    69121 ggtcgcgttc agctttatca ttattatgac atctggcttc aacaagttgt ttctatggca
    69181 aaaccagtcc aatttctctt catctttcgg caataggtta ttctaacata gtttttcgtt
    69241 ttctgcaagt ttacagattt ttatttcatt tgctgaagtt gttctaccac ttcaaataag
    69301 cccatgctgt tgctgccttt tagcataata ctatctgttg cttcaagatt ttgtttgata
    69361 gcatcaatca atttattctt ttctttttca aaatagaaca caggtagttg ggggtatttt
    69421 tggttcaatt cttcttttag tgcatgcatt tgttccccat aaaggaaaat catggcgaat
    69481 ttctcaggat cgatatgttc actcatttgc gcatgcatat ttaaagactc tttccctaat
    69541 tccagcatat ctgctaacac agcgattctg cgtccttttg ttggcagatt tttaaaagta
    69601 tctaatacca gtcccatggc tgttggattt gcattgtaga catcgctcaa aatagctgca
    69661 ccatttcctg ccgttagcca ttcggttctg ttttgagtga tagaaacatg ggcgagccct
    69721 tggcgtatct caggtatgga cagtccaaag aagcgcccga tcgtatacgc aatcaaagca
    69781 ttcgttacat tataacttcc aggcagcggg atcgtaaatg tttctccttc tactacaaaa
    69841 tcggtttgtg cttttccttt tgctgtcact tccgcatgaa catcgccatt tccaataccg
    69901 aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg tcagcaacgg ttcatctgcg
    69961 ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga tttccatttt ggctttagcg
    70021 attccttctc gcgacccaag attttctatg tgtgcttcac cgatcattgt gattgctgca
    70081 gcttttggtt gagccataag tgaaagttcc gtgatttcat tggcgtgatc catgcccatt
    70141 tccaaaacga tcttttctgt atcttggggc atgtgcaaaa tcgtgtaagg aagaccaata
    70201 ttattgttgt aatttccttg cgtcttatat gttttgtatt tttcagacaa gacagacgcg
    70261 gttagatctt tcgtggtggt tttaccattg cttcctgtaa ttgcaacgac ttctgcgcct
    70321 actttttcca agtaataggt tgccaattgc tgcatggctt tcaaaggatc tgctacagga
    70381 ataactggaa aattttttgg agcttgttca acaggcaagc tccaaaatga agcagatgct
    70441 ccgtttgtga tcgcttgctg gataaattca tgtccatctc gcgtaccagc aagaggaacg
    70501 aataaacttc cttcggttat cttccggctg tcaaattcga cattggtaat ctttgtcagt
    70561 gcagagcatt cgctgcccac ggcttgtgca atttcttgta ttgttagatt cattgagatc
    70621 tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac ggcgggttcg catgactctc
    70681 acttccaagt aaatttctct attcgtattt agaagctaga atgaacgcgg ttacgcaatc
    70741 actccagcct cttctttatt tctctttatt catttttttc aaaaaaagat tgacgctgat
    70801 ggtatcgatt cattcctaac tggatcagtt cttcaatcaa atcaccgtat ttcaagccca
    70861 tattttccca taagagtggg tacatactga actccgtaaa tcctggcata gagtttaatt
    70921 cattcaggaa taattcattt ttatttgtca aaaagaaatc gcaccggctc aatccgcttc
    70981 cacctaacat cgtgtaagct aacttcgcgt actcttgcgc tttttgataa acttcttctg
    71041 gcacttcggc tggaatctgc atttcgattt tattattgat atattttgct tcataatcat
    71101 agaatgctac gtcttttacg acttcaccag gcaaagtcgt ccgaacgtct tcatttccta
    71161 atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc aacgattgct cgagaatcat
    71221 actgataggc tgttgctaaa gcattttgca gctcttctcg gttttctgct tttgtaatgc
    71281 cgacactaga acccatattc gccggtttga caaacatcgg ataaagcaaa gaaccttcac
    71341 attgatcaaa tactttttta ggattttctt tccattgatt cttaagtact ggtacataag
    71401 gaacttgcgg cacaccagca gcttgtaaaa tatacttggt catgatttta tccatggcac
    71461 atgcactggt caatacgcct gcgccgacat aaggcatatt caatgtctct aagaagcctt
    71521 ggatcgttcc atcttccccg tttggcccat gtaaaactgg aaaaacgatg gctccttctt
    71581 ctttgatttc gcccggattg atcacttttc ctgtaaagcc ttcctctgtc tgtccacttg
    71641 ggtcccatga aagatgcaag acatctttgc tggcaggttt ttctgttagt aatggacctt
    71701 tgacccattg tccttctttt gtaataaata cgagttgaac ttggtaataa ttataataaa
    71761 tggcatttaa aactgaaaat gcggaaagaa tggacacttc atgctctgcg ctgcgtccgc
    71821 catatagtaa agtaatcttc aaaagattgt cctcctgtat tctaaatcgt tcagtgattt
    71881 actctcatat tttagcacaa aacaaaaata aacgaataac ttatttataa aaaaacgagc
    71941 cagcttctaa aagaacgagc gtcatttatt ttttgtcagc tagattattt gtcccgtttt
    72001 ttataaaaag ttatgataaa gaaaaggagg gatgatgatg gcgcaaacaa atccacgcag
    72061 ccgcttggca gaaatcattc gagtgttcat caattacaat gtagtgccaa actttgtaca
    72121 gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa ctaggcccca ccttcatcaa
    72181 gataggacag atgctttctg ttcgagaaga tttgctttct tctgccttca ctcaaacatt
    72241 caaaacatta caagatagtg tacctagcga cacattttca acggtcaaaa agacgatcga
    72301 aacagaactt tctctttcat tatcagatat attcgatgat ttttcaaaat cgccttttgc
    72361 ctctgcttct atggggcagg ctcatcgtgc caagctgaag aacggtgacg cggtagtcgt
    72421 taagatccaa caccctaaca tcgccgaaga gatccgactt gatcttcaac tatttgaacg
    72481 agcgatccct ttgatcaaat acattcctga aactagcgta gttgatctaa aaggggtact
    72541 ccaagaagta aaacgttcct tgatcaatga aatggacttc ttaaaagaaa gtcaaaatgg
    72601 cgaacaattc tatcaaaaga acaatggctg gaaagagatc cgcagcccca agatttatga
    72661 cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg tctggtaaaa acttgaatca
    72721 tttaatgaac gccgaaaaca aaactgaaac ttttatcact ggaattcaaa acaagcagct
    72781 gaaacaagaa gttgcaaagc ttttagttga gaactttatg aaacaggtgt ttgatgatgg
    72841 ttttttccat gctgatcctc atccagggaa tctgctattc catgtactaa caaaagaaga
    72901 acagacacaa gctagccgaa aaactgaaac agtccatgaa aaagagttcg gttcctttgc
    72961 ttttcgagcc tccacttctg cagaagaccc tgttgcgcca tataccatca actacatcga
    73021 ttttggtatg atggggcatc tttctgcagg acttaggcaa aaactcacac aagccgtttt
    73081 agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg gtccttcgac tttgtcagca
    73141 agaaggctcg tttgatgaaa gtcggttcca ccaagaactg acaagttttc ttgaacagta
    73201 ttatgattct cctattgatg aaatcaactt gcaagaagta ttcacacatg tcgtgacgat
    73261 ttgtcatcaa aataatctgc agttcgatcg tgatatcacg cttttgctga aagcatttgg
    73321 gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt tccctcatgg aagtcgcttc
    73381 gccttttgct caacattatt ttctcactca tctggatgta gaagatacat tgaaacaaag
    73441 cggattagac ttattggaag ggatgaaggc tgcgcctaag atccctcaac agctccacca
    73501 tctattagaa atgtggactt cgggacaagg aaaagtcaat ttggaattga aaaagcaaga
    73561 caaattattg agcaggatcg aaagtatgat caatcggctt gttttcggta tgattttagc
    73621 tgcattgatc gtagggtcct ccctgcttgt ccaagcagca cctgtagaaa acgcagaggt
    73681 cgtttcctta ttagggatat ttacgtatgc tattgccgca ttcgtcatta tttttttggc
    73741 aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag tagaaaaagg ttgtgacaga
    73801 aagaatcagc ttcaagaaat aagaaggggt tttacataaa ttgtttctca aatttttgtg
    73861 aaaattcggc ttatttttcg aagaggctac ttctgaaaca ccgagaataa aaaatgtgaa
    73921 aaagctgttc tgcacccagt aataagaaca atcaaaaagg gaacatggaa cacatttatc
    73981 ctgtttccct gttccctttt tgatgtattc gagcataaat aaaatacctt cgttacctac
    74041 tatcttctgt acttggtaaa ccttagtcaa ttgccttttt taacgcttga cgaaaagaca
    74101 tatgatcttt ctccgtaaag ggttttggac cctttgtcct tatgccagct tttcttaact
    74161 ttccactatg ataacgttgt tctagaagcg tgccgatatt cgcttcgtca aattcttttc
    74221 cagagtgatg gaacactcgc acacccttcg gcaatacaag tgaagctaaa ccataatctt
    74281 gcgtgatcaa aaagtcattc ttcttaacca taccgacgat tttataatcc gcactatcag
    74341 ctccgcggtc tacgtagacg atttggacat gattagcgta ttctttggtc gtataatggt
    74401 ccacactggt cacgataacc acgtcaagac cataggattc tcctaatttt atgacatctt
    74461 cttttactgg agaaccatct ccatcaatga atagcctcat tctttttcgc cttcttccat
    74521 aaatgataaa cagttactaa tccgctcagt aaaagaccaa cattgatcca ttttgccaag
    74581 ataagcagtt gtacactttc tatcggcact gattcatggt tcagcgtgat caataataga
    74641 tggattggct ctcccatttc ttttgctaaa acaaacaaaa gcgtcatcaa taaaaactgg
    74701 tggatcacac tccctttatt ttgagtagta tacttgacaa cgatccggcg atccattgga
    74761 atagctgtat cagtttgata atattcctta tttagccagc tgcctgttac tacgtgccag
    74821 aaactaagca gaaagacacc tatcgcaaaa ccatttggaa tcaagaggac caataaagaa
    74881 gaactcagtc caagcaattg catagccaat ggagaccatg ttaaacgttt caaaatccat
    74941 ggtccgacta tttttgctgc aatcaagcct gctgcataag gcaaatacat aaaaatcgaa
    75001 agtttttcta atccgtacag tatgccaaca taaaaactgc taaataaaaa aaggaaattc
    75061 cctagcattc catttagaaa agtaaacaga tttagccagc ttggcaactt ccattccttc
    75121 ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca gcaagaaacc ataaatagca
    75181 agatcaaaaa gcctttcatc gaataacaat cgggcatttc tcaaaagaaa caataagcca
    75241 aagaatatca aaaataaaac aagctctcgc gtagctacca gatttctttt gatgtctttg
    75301 aaatccagtt cgtaacgcgg ataatgacta accgtatggt aggccatgac gtaaaaaagt
    75361 gtataaatag taaagcttgc tgcaatctga gtcggtgcag gcaactcaat cgcttgatac
    75421 aggagaaata gccagatagc tgcaaataag tactttttcc catccatatt gataaaacct
    75481 tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta caagccatgc tgcactcagc
    75541 cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa atacgcctaa tattccaagc
    75601 aatgaaccag caccaccaat cagcagagcg atcatcagca acgtgtaact atctagacca
    75661 aatcgtagac tgttgactaa aaatagtcca gtcatccgaa aggcataaaa cagcgtaaat
    75721 ggcaaaatcg tcagccaatt atgcgagtct gttagtccca aaaataaaag ataaggaata
    75781 aaaataaccg tgttacttaa gataaagggc gttgtttgtg taaaattacg cccaaatcgt
    75841 ttgagttttt cgaacatgac aatggctcct taaacagtct tataactaat ctgctcttcg
    75901 attttagcat taaaggggaa ataaaccaat tttacagaat atattcttgt aaaaaaaaat
    75961 acagaaagaa gcataagctt ctttctgcat ttttacggta cttgattact caagcagaca
    76021 agcccttctc cacaaaagtc ttgcccgaca cccctgcatc cggcaggtga taaagataga
    76081 aatcaattat cctgtgcctc caaaatcaat taggagctct gtaaaccaga gtccttctcg
    76141 acccgtcgca taaatttact ttaacacagt tcctatgttt atgcgagagc ttttttcatt
    76201 ttataatcga ccatttgaaa tccttgaccg atatctgaaa taagttcttc tgtaatctca
    76261 aatccttcat gcttataaac ctcgattgct tgatgattcc cctgattcac tcgcaaaaag
    76321 atctctcttt cctttgtttg cgcagcaagt tcttcatacc agcgaaaaac tgaagaagtc
    76381 aatccttgac cacgtacttt atttagcaaa tataatttac ttaaataaat ttttccattt
    76441 atctcttcat aagcagtgta accgacagtc ttttcttcgc tttttaataa aaagtaggac
    76501 acaccttctg tcagttcttt ttgaatctgt ttttttgact gataagtttt cagcatgtaa
    76561 tccacttgtt tttgaccaat gatcggcaca aaaacttccg gccatacttc ttgtatgact
    76621 gccatcagct catccagttc attttctgtt acttttattt tttccataca cccacgtcct
    76681 tttttacatt ataaatgacc ttgcgcttga tggaataaaa agagcatgat catgctatac
    76741 acacccaccg accacggttt caagaaaatc acaatctgca taaattccct aaaagataat
    76801 ttcgtcaaac cagctactag acagatcaag tcgtctggcg caaagggaag cagcaaggta
    76861 acaactagta cttttttaat atctttcgtt tttcttgtca gcaattcatc aaatttctga
    76921 tacttttttg gcgataaaat aagctggaca aaggctacgc catagtaacg gacaagcaaa
    76981 aatccgattg cttccccaat cactaggcca atacaactat ataaaagccc aaatccattg
    77041 ccaaacatca gcatgcccgc tactgaggag atccctcccg gcaaaatagg aatgatcact
    77101 tggatcactt gcaacagaac aaatatcatc actgcatact tgccaaattg ctggataaac
    77161 gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat aagcataaag aatcaacaca
    77221 aagaaaaaaa acagaccaat aatgggcatg atctgaagac atttttgtaa aactgatcct
    77281 tttttagaca tctatattcc ccacatcttt tttcatttat taaaactgcc tcct
//
LOCUS       DACCVH010000004        66846 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.004, whole genome shotgun sequence.
ACCESSION   DACCVH010000004 DACCVH010000000
VERSION     DACCVH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.004"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(71..1333)
                     /locus_tag="IVV98_000316"
     CDS             complement(71..1333)
                     /locus_tag="IVV98_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806003.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            complement(1326..2225)
                     /locus_tag="IVV98_000317"
     CDS             complement(1326..2225)
                     /locus_tag="IVV98_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806004.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            complement(2370..4148)
                     /gene="uvrC"
                     /locus_tag="IVV98_000318"
     CDS             complement(2370..4148)
                     /gene="uvrC"
                     /locus_tag="IVV98_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP7806005.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            complement(4330..4644)
                     /gene="trxA"
                     /locus_tag="IVV98_000319"
     CDS             complement(4330..4644)
                     /gene="trxA"
                     /locus_tag="IVV98_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP7806006.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            complement(4731..7091)
                     /locus_tag="IVV98_000320"
     CDS             complement(4731..7091)
                     /locus_tag="IVV98_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP7806007.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            complement(7206..7754)
                     /locus_tag="IVV98_000321"
     CDS             complement(7206..7754)
                     /locus_tag="IVV98_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP7806008.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            complement(7813..8250)
                     /gene="zapA"
                     /locus_tag="IVV98_000322"
     CDS             complement(7813..8250)
                     /gene="zapA"
                     /locus_tag="IVV98_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP7806009.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            8452..9369
                     /locus_tag="IVV98_000323"
     CDS             8452..9369
                     /locus_tag="IVV98_000323"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP7806010.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            complement(9457..10368)
                     /locus_tag="IVV98_000324"
     CDS             complement(9457..10368)
                     /locus_tag="IVV98_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7806011.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(10769..11347)
                     /locus_tag="IVV98_000325"
     CDS             complement(10769..11347)
                     /locus_tag="IVV98_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7806012.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            complement(11367..12035)
                     /locus_tag="IVV98_000326"
     CDS             complement(11367..12035)
                     /locus_tag="IVV98_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806013.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            complement(12050..13120)
                     /locus_tag="IVV98_000327"
     CDS             complement(12050..13120)
                     /locus_tag="IVV98_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806014.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            complement(13291..14655)
                     /locus_tag="IVV98_000328"
     CDS             complement(13291..14655)
                     /locus_tag="IVV98_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7806015.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            complement(14652..16211)
                     /locus_tag="IVV98_000329"
     CDS             complement(14652..16211)
                     /locus_tag="IVV98_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806016.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            complement(16267..18747)
                     /locus_tag="IVV98_000330"
     CDS             complement(16267..18747)
                     /locus_tag="IVV98_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806017.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            complement(18731..19066)
                     /locus_tag="IVV98_000331"
     CDS             complement(18731..19066)
                     /locus_tag="IVV98_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806018.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(19080..20114)
                     /locus_tag="IVV98_000332"
     CDS             complement(19080..20114)
                     /locus_tag="IVV98_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP7806019.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(20204..20884)
                     /locus_tag="IVV98_000333"
     CDS             complement(20204..20884)
                     /locus_tag="IVV98_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7806020.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            complement(21168..22271)
                     /locus_tag="IVV98_000334"
     CDS             complement(21168..22271)
                     /locus_tag="IVV98_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP7806021.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(22493..22963)
                     /locus_tag="IVV98_000335"
     CDS             complement(22493..22963)
                     /locus_tag="IVV98_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP7806022.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            23296..24936
                     /locus_tag="IVV98_000336"
     CDS             23296..24936
                     /locus_tag="IVV98_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP7806023.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            25090..26412
                     /locus_tag="IVV98_000337"
     CDS             25090..26412
                     /locus_tag="IVV98_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP7806024.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(26474..26905)
                     /locus_tag="IVV98_000338"
     CDS             complement(26474..26905)
                     /locus_tag="IVV98_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806025.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(26969..27805)
                     /locus_tag="IVV98_000339"
     CDS             complement(26969..27805)
                     /locus_tag="IVV98_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP7806026.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            complement(28547..29173)
                     /locus_tag="IVV98_000340"
     CDS             complement(28547..29173)
                     /locus_tag="IVV98_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806027.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(29468..29803)
                     /locus_tag="IVV98_000341"
     CDS             complement(29468..29803)
                     /locus_tag="IVV98_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP7806028.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(29790..30074)
                     /locus_tag="IVV98_000342"
     CDS             complement(29790..30074)
                     /locus_tag="IVV98_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP7806029.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(30130..31653)
                     /locus_tag="IVV98_000343"
     CDS             complement(30130..31653)
                     /locus_tag="IVV98_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP7806030.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(31646..32821)
                     /locus_tag="IVV98_000344"
     CDS             complement(31646..32821)
                     /locus_tag="IVV98_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7806031.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(32825..33010)
                     /locus_tag="IVV98_000345"
     CDS             complement(32825..33010)
                     /locus_tag="IVV98_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806032.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(32976..34670)
                     /locus_tag="IVV98_000346"
     CDS             complement(32976..34670)
                     /locus_tag="IVV98_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP7806033.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(34667..35140)
                     /locus_tag="IVV98_000347"
     CDS             complement(34667..35140)
                     /locus_tag="IVV98_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAP7806034.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(35209..35364)
                     /locus_tag="IVV98_000348"
     CDS             complement(35209..35364)
                     /locus_tag="IVV98_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAP7806035.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(35498..35878)
                     /locus_tag="IVV98_000349"
     CDS             complement(35498..35878)
                     /locus_tag="IVV98_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP7806036.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(35882..36097)
                     /locus_tag="IVV98_000350"
     CDS             complement(35882..36097)
                     /locus_tag="IVV98_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806037.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(36100..36507)
                     /locus_tag="IVV98_000351"
     CDS             complement(36100..36507)
                     /locus_tag="IVV98_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAP7806038.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(36773..38248)
                     /locus_tag="IVV98_000352"
     CDS             complement(36773..38248)
                     /locus_tag="IVV98_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAP7806039.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(38238..39086)
                     /locus_tag="IVV98_000353"
     CDS             complement(38238..39086)
                     /locus_tag="IVV98_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAP7806040.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(39123..39485)
                     /locus_tag="IVV98_000354"
     CDS             complement(39123..39485)
                     /locus_tag="IVV98_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806041.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(39785..40409)
                     /locus_tag="IVV98_000355"
                     /pseudo
     CDS             complement(39785..40409)
                     /locus_tag="IVV98_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(40406..40717)
                     /locus_tag="IVV98_000356"
     CDS             complement(40406..40717)
                     /locus_tag="IVV98_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806042.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(40761..41054)
                     /locus_tag="IVV98_000357"
     CDS             complement(40761..41054)
                     /locus_tag="IVV98_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806043.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            41248..41895
                     /locus_tag="IVV98_000358"
     CDS             41248..41895
                     /locus_tag="IVV98_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806044.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            41956..43101
                     /locus_tag="IVV98_000359"
     CDS             41956..43101
                     /locus_tag="IVV98_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7806045.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(43182..43487)
                     /locus_tag="IVV98_000360"
     CDS             complement(43182..43487)
                     /locus_tag="IVV98_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP7806046.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(43512..43943)
                     /gene="ruvX"
                     /locus_tag="IVV98_000361"
     CDS             complement(43512..43943)
                     /gene="ruvX"
                     /locus_tag="IVV98_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP7806047.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(43940..44206)
                     /locus_tag="IVV98_000362"
     CDS             complement(43940..44206)
                     /locus_tag="IVV98_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP7806048.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(44461..45186)
                     /locus_tag="IVV98_000363"
     CDS             complement(44461..45186)
                     /locus_tag="IVV98_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP7806049.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(45547..45617)
                     /locus_tag="IVV98_000364"
     tRNA            complement(45547..45617)
                     /locus_tag="IVV98_000364"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45583..45585),aa:Gly,seq:ccc)
     gene            45734..46486
                     /locus_tag="IVV98_000365"
     CDS             45734..46486
                     /locus_tag="IVV98_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP7806050.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            46502..46981
                     /locus_tag="IVV98_000366"
     CDS             46502..46981
                     /locus_tag="IVV98_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP7806051.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(47232..48812)
                     /locus_tag="IVV98_000367"
     CDS             complement(47232..48812)
                     /locus_tag="IVV98_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP7806052.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(48805..49548)
                     /locus_tag="IVV98_000368"
     CDS             complement(48805..49548)
                     /locus_tag="IVV98_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806053.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(49724..50500)
                     /locus_tag="IVV98_000369"
     CDS             complement(49724..50500)
                     /locus_tag="IVV98_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806054.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(50748..51584)
                     /locus_tag="IVV98_000370"
     CDS             complement(50748..51584)
                     /locus_tag="IVV98_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP7806055.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(51595..52524)
                     /locus_tag="IVV98_000371"
     CDS             complement(51595..52524)
                     /locus_tag="IVV98_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP7806056.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            52716..53069
                     /locus_tag="IVV98_000372"
     CDS             52716..53069
                     /locus_tag="IVV98_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP7806057.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(53143..53799)
                     /locus_tag="IVV98_000373"
     CDS             complement(53143..53799)
                     /locus_tag="IVV98_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP7806058.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            54025..55959
                     /locus_tag="IVV98_000374"
     CDS             54025..55959
                     /locus_tag="IVV98_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7806059.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(56045..57268)
                     /locus_tag="IVV98_000375"
     CDS             complement(56045..57268)
                     /locus_tag="IVV98_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP7806060.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(57262..59160)
                     /locus_tag="IVV98_000376"
     CDS             complement(57262..59160)
                     /locus_tag="IVV98_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP7806061.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(59154..60272)
                     /locus_tag="IVV98_000377"
     CDS             complement(59154..60272)
                     /locus_tag="IVV98_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP7806062.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(60355..61188)
                     /locus_tag="IVV98_000378"
     CDS             complement(60355..61188)
                     /locus_tag="IVV98_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7806063.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(61181..62098)
                     /locus_tag="IVV98_000379"
     CDS             complement(61181..62098)
                     /locus_tag="IVV98_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806064.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(62325..63449)
                     /locus_tag="IVV98_000380"
     CDS             complement(62325..63449)
                     /locus_tag="IVV98_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7806065.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            63632..64540
                     /locus_tag="IVV98_000381"
     CDS             63632..64540
                     /locus_tag="IVV98_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806066.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            64681..66294
                     /locus_tag="IVV98_000382"
     CDS             64681..66294
                     /locus_tag="IVV98_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAP7806067.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        19831 a        13571 c        11230 g        22214 t
ORIGIN      
        1 aaaataggtc tatacaaaaa gaagctggga acaatagatg tccagcttcc ttctgtattt
       61 taggattgtt ttatgctttt tttcgttcat tcctcataat tgaaatcgat tgtttcaatg
      121 aactccataa tccgccttcg ctataaacga gtacattcga tttgtacatg tttgcagaca
      181 agatcatcaa taagaatgtt acggctacaa gtaccaacaa ggaaatcaat gctccaccca
      241 taccgactgt ctcatttgct aagcgaaccg gcataatata tgaagataag aatggaatat
      301 acgaagtgat ccgaataacg atattgtttg gatctgaagc tcctagtatc aatccaagca
      361 tgtatccgcc tagagataga taagtcactg gcaaaattgc ttttgctgta tcttctgctt
      421 tgttgaccaa agagccacat aaagctgcta aaacagaaaa aatcaaaatg ccaaagatca
      481 tgaatagaag agaataccac aagaatggtc caatcaagtt atccaatgag ataccgtcta
      541 atatattttt gaccatttcc atatctttga attgactgta tcctatacca aaaataatac
      601 cgtataatgc catttgcgtt aatgcaacaa gtaaaacacc tgttaatttt ccgtaaaaat
      661 gcttttgtgc agtcgtactg gacaggatca cttccatgat ccgcgtgcct ttttcagaag
      721 cgatctcttg tgcaatgatc tgcgcatacg tcaaaataat aatgaacaag acaatcgttg
      781 ctacataact tacgacgtat tggactgtcg agttatcttc tccgactgtc atttttcctt
      841 ttgaatcaaa attgactttt tgtcgagtca aacttgcttg ttggctcaag ctagctactt
      901 cttctggtga aatgcctaat tgactcgctc gaagcatcga ttgcaagcca gtcagttgtt
      961 gttgtatcag tagttgtgta ctttgtccta atgaattttc gctataaagc atcccattta
     1021 tcttatcatt ctcagttgag actactaaat acgcatcgat tttttcttcc gaaagctctt
     1081 tttgtgcttt ttcttcagaa tcaactgctt tgaactcaaa atcatctgtt ttgacttggc
     1141 tcatttgctg actgatttgc tcattatcag ccaatacgcc gattttattg acatcactat
     1201 tttgttgagc aaagtttcct gctacataaa tgatacccag catgataaaa gggactaata
     1261 tcatgatcaa gaaagaaatc gacttaacat tttttaaata gacatctttg gtaataatcc
     1321 aaaacttacg catcgatttc acctgctttc aatttgaaaa tctcttccaa agttggcggt
     1381 tgctggttaa acataggaat gtagccgaac tgagtcgcac gagtaaagat ttctttccca
     1441 gcttcaggat cttctaaggt aatctctaac gtattgtctt catgaaggat cacttttttc
     1501 acgccttcga tttcttctac ttcctgttgg cttaaaccag attccaagaa taacttcgta
     1561 cggccaaatg attcacgaat ctcatgtact tttccattca aaaccatttt tccgtttcgc
     1621 aacatgatca aatgatcgca gattttttct acattatcca tattgtggct agaaaaaatg
     1681 acacatgaac catgtttttt caattccaat attccatctt ttagcaattc agcatttacc
     1741 ggatctaacc cgctgaatgg ctcatccaaa atgatcaatt taggttcatg gattaacgtg
     1801 gcgatcagct ggactttttg ctgatttcct ttagacaaag attttacttt atccgtcttt
     1861 ttccctttta cctgaaattt ttccatccaa aagtcgattt ttggttcaat ctcttttctt
     1921 gatttccctc taagttctgc aaaataaagc agttggtctt gaatcgttac tttcggataa
     1981 agtccccgtt cctccggaag ataaccgatg acatcataat ctttctcccc aagatgatgg
     2041 ccattccata acacttctcc ttggtcttgt gtcaaaaaat ccaagatcaa acgaaaagtc
     2101 gttgtcttcc cagccccgtt ttggccaatt agccccatga tttttccatc ggggatttgg
     2161 aaagagacat gatcgacagc tgtgtagttc ccaaaagttt taacaagatc cttgacttct
     2221 aacatttctt cactccttct tcaagaaatc acatatatcc ttagacacca gacgtaagcg
     2281 atttattatt taccaacaaa acgtaaacgc tctttttgtt gtacataaaa tgataggaca
     2341 ctttactttc tttgtaaagt gccctttcct cattcctgat gtaatttatc aaatacgttt
     2401 tgtgcgacat ttttcggcag tccgatttct tgtaattctt ctgtcgtggc tgctgtgata
     2461 tttttcaacg atttgaactc tttaagcagc attttttttc gttttggtcc taacccttca
     2521 atttcatcta atcgggaagc aaaactgttt ttactgcgta gctgccgatg gaaagtgatt
     2581 gcgaatcgat ggacttcatc ttggattcgc tggagtaaga aaaactctgg tgaatttcgc
     2641 tcaagcggta ctacagccaa atctgtaccg aatagcaact catttgtttt atgtttatcg
     2701 ttttttgcca tgccagcaat aggaatatcg attcctaatt gattttctaa gacatctttt
     2761 gccacatcta cttgtccttt tcctccatcg atcaagatca aatcaggtaa aggcaaccct
     2821 tcgcgaatca ctcgcgaata tctgcgatag atgacttctc tcattgatgc ataatcatcc
     2881 ggtccgttga ctgtttttat tttatatttc cgatattctt ttcttgccgg ttttccatca
     2941 atgaatacga ccatcgcagc cacaggattc gtccccatga tattagagtt atcaaaagac
     3001 tcgatacgta ttggggtcgg gatattcatc gcgtttccta aacgttcaac tgctccgatc
     3061 gtccgttcct gttttctggc aatcagatca aaccgttcat tcaaagcaac tgaggcattc
     3121 ttactcgcca attcaactaa ttttttcttt tctcctcgtt ttggttgcag cactttcgta
     3181 gctaacaaag cttctacact gggcttgtcg atcgtatcag gaatcaagac ttctttagga
     3241 atgaaatgct cattttcctg ataaaactga ccgaggtaag tcaagaaatc ttcttctgct
     3301 tcgttataga aaggaaacat tgaaacatct cgttcaatta gctttccttg tcttacgaaa
     3361 aacacttgga cacacatcca tcctttatca atcgcataac caaatacatc tcgatccagt
     3421 aaatcagtat ttgtcatttt ttggcgagtc atgattgtct caatggcacg gatctggtct
     3481 cggtattctg cagctttttc aaactccatg ttttcagcag ctttttccat tttctgatgg
     3541 atctctgact cgattttttc gtgtcctccg tttaaaaagt ttttcacttc atcaacgatt
     3601 ttcgtataga ctttcggatc tacgtcgaaa taataaggac acagacattg tcccaaatga
     3661 tagtaaagac aaggctcctt cgtctgacta ggtttgcatt ttctcagagg aaataatcga
     3721 tcgaggatct tctttgtctc attcgccgca ccgacatcgg gatatggtcc aaaatacagt
     3781 gctttgtctt ttagtacctt acgagtaatc accaaacggg gatatttttc attcgttatc
     3841 ttaaggaaag gataggtttt atcatccttt aacataatgt tgtatttagg atcatttttc
     3901 tttatcagat tgatctctaa gagcaatgct tcgatattcg attctgtaac gatgtattca
     3961 aagtcttcga tttcactaac aagccgttcc gttttcgtat tatggctacc agtaaaatat
     4021 gagcggacac gattttttaa tattttggct ttgccgacat aaatgatcgt tccattttta
     4081 tctttcatca agtaacagcc gggctgatca ggaagtaaag ctaatttgtt tttgattcgt
     4141 tcgttcatct ggtactcccc ttcatattca attaaagtta ttatagcatg tctgtcaaaa
     4201 aaacaatcca gcctgacaac gtaattatac tcaaaaaata ttaatttgaa taaccttaac
     4261 tcaaccgcaa aaaaaccgag gacggaactg gattcagtcc caccctcagc ttatttttgc
     4321 tgtaagtttt tataaatatt gatcgatcat ttgacgtagt tgttcttttg aatgaacacc
     4381 aacagctttt tctactactt gaccatcttt tttcaacatt aatgttggaa tgctcatgat
     4441 accgaattgt tgaggagttt ctggattttc atccacatcc attttagcaa ttctgaattc
     4501 ttcttcatca tattcttgtt ccaactgatc caaaatcggt gcttgcatac gacatggacc
     4561 acaccaagtt gcccaaaaat caatcaatac aagtccttta tctgtttctt cattaaatgt
     4621 cttatctgta attacttgtg acatatcaaa gacctccatt tttaaaatct atgactagta
     4681 tagcatttct atacttggat agcgaaccat ctgcttacct ttagtaagct ttacttaaat
     4741 ttaacaattg tcgcaccatt tccgccttgg tttgccggtg caaactcaaa gcttttgacg
     4801 ctccgatggt ttttaagata atcagtaatt cccttgcgaa gtgcgcctgt tccttttccg
     4861 tggacaatag tcacttgagg ataaccagct agaatggcag aatccaaata ttgatctacc
     4921 tcacttagcg cttcttcgta tcgttttcct cgaaggtcca attgattcgg cacgtgacta
     4981 ctagattcag atcgtacagc atggataact cgttgtgtcg gctctttttg aggagcaaca
     5041 ggcgtcagct cgtcttcgga cacattcatt tttaatatac cgatttctac ttgccactga
     5101 ttcccgtttt tacgtaaaag cgtccctctt tggccgtaag tcgtaaccaa cacttcgtct
     5161 cccggtttca acgttttttg ttctttcgcc ttcttcaata ctttattttt cttcaaagtt
     5221 tcttcttgat gtagatttgc taattgggtc tttgcatcga tcaactgatg ctctttcaca
     5281 tttccttgcc caatctgctg ttgcatttta cgaatatcag caatgatttt ttctgctttt
     5341 tcttccgcct ctgacacgac ttcatttgct tttttctttg ctttttccat ttctttttca
     5401 cgttcttcaa agaaatagct gtaagcttct ttcaaatcat cgtgaagttc ttgtgcctca
     5461 gaaacaaaat gacgcatttc cagatattcg gtctctgcca ttttccggcg attctctaaa
     5521 tctgtgatca tttcgtttaa atcttggctc tcatcattca tcaactgctt cgcttcatca
     5581 ataacttctg tatcaagacc taatcggcta gagatttcaa acgcattgct tcgtccagga
     5641 acgccaatca gcaaacgata cgttggactt aatgtatcca catcaaactc catgctggca
     5701 ttaatcgtat ttgcccgatt atatccataa actttcaatt caggataatg cgttgttgcc
     5761 atcacataag cagacttttt accaagatca tctaagattg cgattgctag agcagcacct
     5821 tcttgcggat ctgttcctgc accgagctcg tcaaataata ccagactttt ttcattgact
     5881 tttgataaaa tatctacagt gttcgtcata tgagaagaaa aggtcgatag actttgctca
     5941 atcgactgtt cgtctcctat atccgcaaat acttcctcaa aaataccgat ttgactttct
     6001 tcacctgcag gaatcggtaa tcctgcttgc cccatcagtt gtaacagacc taaagtcttc
     6061 aacgtgatcg ttttcccacc tgtgttaggt cctgtaatga cgatggcttg atagtctttt
     6121 ccgattgtga tgtcattaga aactactttt tcctgatcga tcagtggatg tcttgcttgt
     6181 ttcaagacga catgattgtc ttcactgatt cccggcacga tagcttttac ttctttacca
     6241 aatcgtgctt ttgcattcat cagatccatt ttaccaatca cataagcatt gtggatgatt
     6301 tcttgacgat ggggaacaag ttcagcagaa agttcactta aaatacgttg aatctcattt
     6361 cgttcagcga tttggtattg acgcaaacga ttattcaaat ccaccacttg ttttggttca
     6421 ataaataaag tctgtcctga agcactttga tcgtggacta caccgccaaa tacaccgcgg
     6481 tattcttgtt tgactgggat aacgtagcgg tcatttcgca tggtgatgat cgcatcactt
     6541 aaatactttg catttttccc acggacgatc ccatctaact gttcacgaac agcttgttca
     6601 cttcgccgaa tgttctgtct tatgctcttt aactcaggag aagcgtcatc agtcacgcgt
     6661 ccgtcttcat cgattgcttc ctttaaacgg cggctcaaaa cagggatcgt gactaactga
     6721 tctgcccaca tatacaaacg tgcaaattcg atttcactgt cataaagatc atcaatgaaa
     6781 cgattcaatt cgcttgtcgt agacaatact ctggaaactt gtgcaagctc cactccattc
     6841 aagtctgctc cgatctcaat ccgtttcata tggggacgga tattttcaag tttaggtata
     6901 gggatcccgc ctcgcagacg ttgcactttc aatccatcct cagtttcttg aagccagttt
     6961 gtgatcgttt gttcctcgct cactggtacc aattctgcca gttcttcttt tccttgtgca
     7021 gtcactacaa attgtctgac catctgtttg actttttcaa attccaatgt ttcaaggatt
     7081 cggttattca ttttatcacc ttatctttca ctatgaaaaa agagctgtgc cggacatacg
     7141 ctacgcagcc ttcttaaata atctactctg tacaaaaaac gaaatatttt ccagcactat
     7201 tttccttaat tcaaaatatt cgttacccaa agctcataca tcttgttggt aagaaatggc
     7261 gttctctcaa cgataaagcg agcgaaacta tgctcgccga attgattttg gaccacatct
     7321 aatggaacaa aggcaagtaa ctgcaaaatc aaaaatatag taacgtaagc catgattagt
     7381 gacaggatgc ctcctgcaat ccagtctacc tgtctcaaga tcggcacata cgtcaatcca
     7441 tggacaaaaa cccccacaaa tcgggtaagc agccagccaa ttagcaaaat aatcagaaaa
     7501 gcagttcctg cataaaaagc ttcatctagg tgaaaggcaa atacctgatc aaaaaatgct
     7561 aactttgatg ttggcgtgac agctgggtat ggaatgtata attccaaatg acttgctaat
     7621 ggtttgtaaa aatgctgggc agcaataaat gacaatacat atccaatcgc gaatatgatt
     7681 tgcaaagcaa acccgcgacg tgctccagaa aaaaacgcaa ttagcaataa aaataaaatc
     7741 agcaaactca gcatgctacg ttcctttctc ttctaacttt ttttaaattt ttcttatttt
     7801 gataaaagga tcttaattag aagatttttg tttaatttgt ccttttcgtt tctcgtttaa
     7861 aatctgttgt gcttccacat gatttttaat ggtatgatct gcttgaccat tttctttcaa
     7921 tacttcccga gcttcgttct cgattgcttc aatgcgtttc acacgatttt caagctctgt
     7981 aaatttgatc atttttttct ttaattctgc tgtttcttct tccagctcca agattctttc
     8041 ttgtttcttc aattgatccg aaagcgcatt gacagccatc aagattgctg cttgttcatt
     8101 atccatttgt ggtgataatt gtttcaattc tgctaactgt tcattgatca gcttcgttac
     8161 gatatccata tgatgcttgg tttcccgtcc gataatagta tatgtttggt tggcaatcac
     8221 cgctttgtag cgtgtttttt cgtgcgccat acgaatcatt tcctcctatt tgatgaaagt
     8281 tttatttagt gtaccatgaa gttggttctt tcaccgttct ccacaaatat ttttcacata
     8341 cttaactatt atatgataaa ctttaaaaaa atgctatgtc tcgcaatctc ttagaaaacg
     8401 aaaagtcgtg agttgcggta tagttttatg tataaaaacg aggagaattt tatgagcaac
     8461 gtcattatca aagcaacaaa cgaccaactt agtcaaatga aagcatacta tcgctcttat
     8521 ttgttaaata aacagattcc ttatactagc tttgctgcaa aaaaagacgg gacgaccatt
     8581 accgcttata catccggaaa agtgatgttt caaggtacga atgcagcaat agaagctgat
     8641 aaatgggggg aggcacagga taaacaagcc aagccagcaa aaacagcctc ttctttgcca
     8701 aaaaatatca gtcaattatc cgttttaggt agtgatgagg tcggaaatgg cagctatttc
     8761 ggtccgctaa cagtatgtgc tgcttatgtg aaacgtgatc agcttgcaga attacgtaaa
     8821 cttggtgtta gagattcaaa agagttaaaa gatagccaaa tcatccagct tgctgacatc
     8881 ttaaaaaaaa ccatccccta taaactgctt gtcttatctc cagaaaaata caatgagatc
     8941 caaccaaaat acaatgccgt tcggatgaaa gtcgctttgc acaatcaagc gatccatttg
     9001 ctgctaaaaa aaatcgagcc agaaaaacca gaagcgattt tgatcgatca gtttacgccg
     9061 gaagcaaatt ttaaaaaata tgcgcgttta gaaaaaaatc aattacaaga aaaactgtac
     9121 ttcgttacta aaggagaaca atatcattta gctgttgctg ctgcttctat catcagtcgt
     9181 gccagctttt tggaagagtt acacaaagca tcagctgaag ctggaatcac ccttccatca
     9241 ggagctggaa cgaaatctga ccaagtagcg gcaaaactat tggagaaagg cggcatgcct
     9301 atgcttgaaa aatatgccaa acttcacttt gcaaatacag aaaaagcttt gaagctacta
     9361 aaaaaataaa cggtgttcaa aagcttgcat ctgcgataat aagcccggcc aaacgaaaaa
     9421 tatgaggagc tatttttgtt tggctgggct tatttattac tgaaaataag tggtcaatgc
     9481 ttgtgtcaaa cttgcagcaa tctgctgctg ataactgtct gttactaatt cctttaaatc
     9541 actatcatta ttcatataac ccatctcgat taaaatagaa ggttgaagat tttctcgaag
     9601 aacttgatag ttcccagtgg agattcctct tgaatccaga ggcagatcag tgaaggagtc
     9661 agcaattgtc tgtgctaatg tttcctcttg tccatagtaa taatatgtcg tgattccagt
     9721 tgcttcattc gcatattccg tagagtctgc gtgtaaactg ataaagacat ctgccttttt
     9781 ttcttcactg tagtcgcata tatctccaag ctgtactaat tcatctgtag tatgggtcaa
     9841 ataaaccgtt gctccagcat cctctagcgc cttttttact tttatggctg tacttaatgt
     9901 tatatctttt tcttctgttt gttcatcatt gcttaatgcc ccagtatcat ttccgccatg
     9961 cccaggatct aatacaatca ctgcatcaga tagctcttcc ggttttgttt gtatattctt
    10021 tgtgactttg gttccatctt cgagggctaa atatccagta tagccatcat ttgtcttgat
    10081 ctgataagca ttttttgttt cagaaagaaa ctccgccagc tctccgccgt ttatagttgc
    10141 aagtggggta gttagcgagt catctgtata tagtgtacgg tcattttttc cgattttgat
    10201 taatgtctct tgttctgtat catcaaatga ttcctttgtc tttgtaaccg tactgttcgt
    10261 actgctgacc gtttgtccaa ctatcttttt ttgaccaaaa acatctattt gaaaacagat
    10321 aataatgata atgattgcaa atacaaaagc tccaattatt tttttcattc ttgactctca
    10381 cctcgtagat ccagactaag ggccaaaact taaaatcagc ttaagtaagc aaaaaagggg
    10441 ctgtaaaaga tataaccgta gaaaataaca ttactgctaa aatgattttt ttcatttttg
    10501 gcatatcctg aaatctcctt ttgactattc gtggtgattc atctacccaa taaatagttt
    10561 ccttcattct acaaacaatt aatttcttcg ttattaaatt aaaacacttc ctggaacacc
    10621 gacataataa ataaaaatat accctgataa tcatgagaga ataacaaatt tgtctttatg
    10681 aaaaactacc tatataaaga agcaagatat aacgatcttc gtcatatctt gcttcttcac
    10741 ctaactattt tctccctata taacagcttt acgcttctcc taatacacca ttcaaatata
    10801 aatcgatcaa ttgcgccaca tttagcggtt cttccacagg tcttttcgac cgagtgatgt
    10861 aaggtgctaa cactaagaaa aaatgccttg ctgcgatttc ttttgaaatc ccatttctta
    10921 gcacagattg gtttgctgaa aagatttctt caaaaggttc acgataattt ttcttccata
    10981 gaaagaaaag atgatctctt gtttcctttg aaagattgct ttcaagatcg tgaagcatca
    11041 gaaacaaatc gaccagatgt gtctcaatca aaaactgcgc catttttgtc aaggttactt
    11101 gaaatcccgt ttcgcttgtt tgaacgattt ctctcaaagc ttttccaaca tcttttaagt
    11161 ggttttctaa aactgccgta tatagttttt ctttatcacc gaaataatga tagagattgg
    11221 gctgggtgat cccaactttt tgtgcgattt ctcttgttga agtgccgaga tatcccttgg
    11281 acataaacaa gtcagtcgct tctttcaaaa ttttttgctg tgtatctttg ttgtatcgat
    11341 ggaccatttt tccacctgct ttttggttat tctttttctt tcaatacacc atcttccatc
    11401 ataaatattc tatcgcattt gtcaatcagc cgtgtatcgt gagtaaccat gatcgttgct
    11461 ttatttttgt cttttgattc ttttgccaag atatcgacta cttctcgtgc cttttctgaa
    11521 tccaaactag cagttggttc atctgctaga ataatggacg gatcattgta caatgcacga
    11581 gcgattgcga ccctttgccg ttctccacca gatagttctt ctggatactt gttgatcaac
    11641 ttatccacgc caagctgctc aaataattcg tttgcttctt tttgacgatg ttcatgttta
    11701 atcttatcta ctaataataa ctgctttttt actgtcagaa aaggaaccag attggaagct
    11761 tgcaaaataa agccaatttc tttaaaacgt agtttaacgc gttcgctttc tttttgatta
    11821 ctgaattctt gatcattgat aaatacagag ccactgctag gcgtctgcaa tccgcctgcc
    11881 aaagtcaaaa aagtactttt acctgaacca gaaggaccga tgattgcaac aaattcccct
    11941 ttatcgatac tcatggttgt ttctttcaat gctttaacta cttggtcgcc atcttggaaa
    12001 cttttttcta cttctttaaa ttctattgct ttcatgttct tcctccttct tatccaattg
    12061 ccttcaacgg atcgattttt acgattgtcc gaacagaaaa tagtgcgcct aacacagcta
    12121 ctactaacat caacaagcta atgacgccaa aaaacagcca attgctttgg aatggaaccg
    12181 catcaggtag aacaagggat gttcccactg ttcctaatag accaagaaga ataccaacaa
    12241 atgataaaat gaatgtttgt gccactacag aacgcgcaat aaatcctcct gtgatccctt
    12301 gtgctttcat tacaccaaag atattaatct tttgcatcgt cagtacataa atgaaaatcc
    12361 cgatcacaat agccgcaata acgatcaaaa atccgatcat aaatccaaaa gtcaatactt
    12421 gcgcattata tccaggtaat tcattgatga atttagaaat tttgatctgt tctaaatctt
    12481 caggtaaatt actgatttta cctctgacaa ctattgcgtt aatccgtgca ttttcacttg
    12541 tatcttcttt ttcgaagcgg atttcttggt aagcattgat ggttgtatag agaactggtg
    12601 agacattgaa tttggcatga tccgtaaagc cagttagttt aaacgtcttg tcactaccag
    12661 ataacttaac tgtatctcct atggctagac catattcttc tttcaaacta atatcgccta
    12721 ctgcctcatc atcgttatca aaagcttttc cttcaacaag attgggcatg atgaattgat
    12781 ttttatcgat accgaagaag ctaacattga tttttccttc ttctgtactg tctttactag
    12841 tcacgactcc aggtgtttgg gcaagatacg ccactttccc accttcgact tcttctgcta
    12901 tcttcttagt aatcatggac atccctagat ttgaatttgc atctttcgaa agcacaatcg
    12961 aatctgcctc ccacttgtcg actgctgttc gattatcttg agctaagcca taagctaacc
    13021 cagtcaaaaa aaataccagg taggcgatca aaaacatcac ccctgcaact aacgcataac
    13081 gtaactttga atgcataatt tcatttaatg ctaaaaacat ttaactcctc ctcctgaaat
    13141 aatcatttta tacaacaatt ttatcacttg ataaattttt ggcgaatatt atgctcaaaa
    13201 aattcttccg ctatttcatt atatgaattt tttattctcg attgattaat atttattata
    13261 tccccacaca ataaaagacc gtgatatttc tcacagtctt ttatctactc tattgctatt
    13321 tgctctctta gctagtactt taaaagctaa ctcattgagg tagtgaaaac gagaggtgta
    13381 ttcagacaga aatccaaaat cctcaactgc tagctgtgga atcgtagttt tgtgtttcac
    13441 gatatccgca agcaggttca aatctgataa taagaattct tggcttatca gctgtccgcc
    13501 aattatttct aatgtatccg gatggtagat cagctttgca tttactgttt tgttttcttc
    13561 gtcgtattgt ggaaatagat caaattctcc tgaacacgaa ccggtatttt gttccaagaa
    13621 tggcgcttca tcttctgtca gccctacagt tcctaaaaag tagtctataa tgactgctgc
    13681 tgttatcttt tgtctgaggt cgtaagcggt tggctgacca ctcaaagtta gcgctactgc
    13741 tcttgccata tgtacagctc gagtaactaa aggtaaaaag agatgccgtt tatttttgtc
    13801 aaaactgact gggacgatat ctccaatcgc atagatgtcc ggatcacttg tctgcagata
    13861 ttcattgact atcacagtct catcctcata caaagccact ttttctttta acaatgtcgt
    13921 attaggacga gtttgggcag aaaaaatgac catatctgcc tttattgttt gagacagaag
    13981 ttgtacggat actactttct cttctgattt tttccaatcg atcaagaatt catttggata
    14041 aaaatttatt tgcttagttt gcagctgatt ttgaaaactg ttgatcatat ccttatcgaa
    14101 atatcttgat aaaacattcg gcatataatc aactagatga ataatgtatc ctttatttct
    14161 caaagcatct gctaattcca atccaatgta accagcaccg aagatcacta cttcttttgc
    14221 ttcttttaaa gcggcaagta cttgcttaga ttgcactaga tttttatagg tgtagacatt
    14281 ttcagcttca atttgtttat acaaggtgac aggagaggaa cctgtcgcta cgattaattt
    14341 atcataggtt atggtctcgt tttttccttc tttggatgcg aggatgagct gatgtttgtc
    14401 tggatcaagt tcagttactc tccattcggt gatcagtttt gccccacttt cttgaagagt
    14461 ccgcatgtta tgggcaactt cagctaaact acgtatcttt ccttttaaat aaaggttgat
    14521 tccatttgaa acatagccta gtccatcttt atgatcttca tcgatcagta aaacttctgc
    14581 tttcggttga agttttctta gatttagggc agctgtgatg cctgcatggg aagcaccaat
    14641 gatcacgatt ttcatgtttt attcatcctt aaattcaatt tttctaaata acattctttt
    14701 aaaaattggt tcaaataggg gaaatcataa ttatattcgt tgctagtgaa tacaaaaact
    14761 ttagcggact tctgtgacgg gtactctttc aattggctag tcaaaatgat atcatactgc
    14821 ttttctttct cgtattcgac taaatcatat ttgatcgtat tcagcaattg ttcctggatg
    14881 atttctttca cgatatccgc cattagcctt tcataaggaa gatcataagc aatttgcaga
    14941 cgtaattcta actgcttgat cagcgtccgt aaaatagatg catagcgagc aaataattca
    15001 aagcgggcat tttcctcgtc tacttcagta aaatcaacaa tagcaaatgt ttgtctgacc
    15061 aatctttcac ataaaaccag gaattgttta tcttctactt cagttaaccg ctgttttaat
    15121 ccttcttggc caaaaatatt catccatcct ctaaaatagg caaaatgagc gtgattttgc
    15181 atcactgtca acgcaatctt ttgcgaaatc tcttctggaa aaacataaaa agagaaatat
    15241 tcttctatcg attgtttaaa cgttcgattc aattgagcta ctacgtcgtc tttgtatttt
    15301 tcgcttatca aaaactcctg gacatgcgag ttatgtgtat ctaatgtaaa gttactgatc
    15361 atgaaaagat aaaaaaccaa cgtttcattt tgattccaag gaaaggcata ttgaaagaag
    15421 taacgggtca aaaatgtatg gaggtccaat aaaaattgtg tcgtttgaaa caatccaaca
    15481 ggaagattgc tataatctgg tttggatttt ttcgtacagc gcattcgctt cttcataatg
    15541 gaaagccata tttcaaattt caatcgtcct tcttctgtaa tagcaaaact aaactctttt
    15601 tgcagcagat ctaaaaaagt gtttcctgat aaatcactgt attctttttt gttttcaaga
    15661 tagggacgtc caaaccaaaa taattggaaa taaaaataac gaatttgact ttctggaccg
    15721 gtcagccgcc cgctttttat tttcagatga aactcattta aagaatcatt taattccttc
    15781 actctgcgag acaaagtagc cgaactgata ttaagttcca tgacaagttt ctgccgatca
    15841 aatgagccat tttccaacag ataaagaagt atctgatatt ttgtagaata gcgcaagtaa
    15901 caatgataat aaacatcgac tgctgctata tttccatgtc tgattaataa aatattccct
    15961 tcttggataa caatttccaa ttgtttgata ttttccaagt tagcttgtaa ataaaacaga
    16021 tcttctttca aggtagcccg atcaactgat aagcgggtaa gtacgttatt aacggaaacc
    16081 tctccttttt cctctaataa aagttggaaa agtttgattt gccgttgttc atttttttca
    16141 agcaaactga aaagttccaa gtccactcct tcaagcattt ctgattttaa cagcagaagt
    16201 ttccttctca tccttgaaaa agaggatctg tgacagttat cacagatcca tacaaattct
    16261 aatcacttag ctggttggcc cagctgtcag tttccatgtg accatgcctt gatacgttgc
    16321 gccaggttga gcattcgtac tgctatttac ctctaagagt aaaccatcgg tatcgggaaa
    16381 gtcaacgaga acctctcctt tagctgttcc atcactctca taaatcaacg tgttttgacc
    16441 ttgctgaatc aattgctttg atccagaatg attgaagtat aattttgttc cgcttaattc
    16501 ttgaccttga tcattcttaa ataaagaagt caatgtacct gtcagttgcc aaggagacgt
    16561 gcttggaagc cgagtatccc gcacatcaaa agaaaaatcg ccttttgatt cataataact
    16621 tgtcttcaac ggtttgggga gatcgttacc aaatgtaaaa tcatctggta cattaactaa
    16681 tgttaattct tgtttgggga caagaattgt tttagcagat gtttggacaa ctgggttagg
    16741 aagcttagca ccatctgcta atgtaatatt gctggaaagt acagctgcct ttgtcagtat
    16801 gctgacggat tgtaaagaag tatctacagt atttaattga tagttgtaag taagatgaat
    16861 ggtatctcct attttgctca atagatctgc tgggacagaa actccttgtt gaatgccggt
    16921 atctgcgata gttgtaccat ttaattttaa ggaaccattg atataagtag tattttcagg
    16981 aagtgagatc gtgatttttt tgtcggttat cgcatcccca gattttgtta acgtgaatgt
    17041 cacattttct tgaatcgtat ctcctgatag agcagacagg ggatctcctg tctcaggttg
    17101 tctgctaagg ttttttagct gactatctgc actcacagat ggaaaattag ccactgttat
    17161 ttgaggaaga gtggtgattc cagcttgttc agactgccat ttgtacgcaa aagacggata
    17221 catgttagta agtacatcgt ccaccaagcg ataatcaaaa taatattgcc ctgaagccaa
    17281 tgcaggtagt gtagaagtag ctgtatttac acccccgtta tttgattgga tcgtttggaa
    17341 aagttgatct gtccatcctg tcgctaattt ttgggttcct ttcgaataaa gcctgtaatg
    17401 gatcgaaccc ttttttagtt cagttgctga ccaattggcc gtgacttggt acgatgcaga
    17461 agaaaggagc tttccccact gactatcggc tgttaagttt gttggtaaaa ccgttccgtc
    17521 tagcttgtac tgctccaata cctttaaagc aacaggagaa agcaatccgc cttgcgcatc
    17581 tttcccactg tacacgatat tggctgtctg attcaatcca cttgtgcttg ctggagtatg
    17641 agtcagtatt gctccttgtg taacgttttt tcctgtaaaa tagttgacta cgcgatcaaa
    17701 gcgactaaat ggcaactgat caaaacgtcc ttcagtcagc cccatcgtca atgtccgact
    17761 attggtagag cctggaaggt tctggttatt tccatccacg tattctgtgg tatcagcaaa
    17821 tgtattatat tttcctgttg aatcacttgg tgagatgtaa ctattccacg tatttatctc
    17881 tgcacttgca gaaaatgcat atgctcctgg attcaagttt ccgccagtta atttaggata
    17941 aaatctacct gcagctggag ctaaaatcga attgaacata cgatcttgga taatattatt
    18001 cgaatcataa aaatcaacag aaaaaacggc ctttttagac atagaaggtt gtaatttacc
    18061 cttggtcaaa attttgtttg gactcgtatc atatttatct ccgttttctg tcatcttcgc
    18121 gacattagct gtaacatcaa attgaagcgg gatatcgtcc acgttgaatt cgcctcgcgt
    18181 aataatagca ataatatctg tcaatagagt atttgtatcc cacgacccca tcccaaaacg
    18241 caaggtatgg cttcctgctg ataataaact tccgctagta accttgatgg gggcaccggc
    18301 aatatacaag taggcgttgt tccagtcaat tgcttttaat acatcactgc ttgatacatg
    18361 ttccggcaaa ttgatgatcg ccacaaatgc aaatccttgt gcagtgatat tcaccaaatc
    18421 aagtacattt gttagtttca catggctttc ccaatgaaaa cggaccgtgc cacctttcca
    18481 aggatcattt gaaccatcgt tcaaataagt agcagtcaat ttaggcaatt ggttagcccc
    18541 agttagttgg acaagcttcc cgccattgac tgcactacgt ccaccatttg gaggtacgat
    18601 attttcatac gtgtatggat cataagaaat ggcaggaggc gttgctccaa cagcttctgc
    18661 cgaaggtgaa aagataaata tacttaaaac aaaaagcgaa gtaaaaaaga aggagcgaaa
    18721 aaatgaaaat ttattttgta gcaacatgtt catcctcctt ttcctttctt ctccataaca
    18781 acaaccacgc aagaagccat aattctatac caatgatcaa ataaagaaaa cggatctttt
    18841 gttcattcgt ctccgggaat acgccatgtt gattagattc tttataaatc ggtagctgtg
    18901 tctgctgttt tgatgcgcca ttgactgaac cacttggatg cggaattgga cttagatcat
    18961 aaaatgtaat cgtacctgaa cttttggtat ctgcttggac tggctcttgc cagctgaaga
    19021 acagcaaact tgcaataatc cctcccaata agatcgatgt tttcaacgaa atcacctcat
    19081 catgttgttt ctcctttttt ctttttcttg tggacccaca aaaacagcaa aatcaaccat
    19141 aacactagaa ctgcagcaac caatcctgca taaagccatg ggaaagattg ttcttgtact
    19201 gcaaaaacgg aattttcatt tactttttgt gctttttctt ttttgatcgt aaagttttgt
    19261 gtaaatcgcc attcattact gtcgcctgat tttgctatga tttctgcgcg gtaatcgccg
    19321 gcttttgctt tatcaccagc taaatcaaga ttcaagtgaa aattcgaatt tggtgcaact
    19381 aaaaatgcat tagacgtatt ttcaatataa agctgatttt cataaaagat cttgctcgta
    19441 aatatcaaat tgctgataat cctaggctga ggattttgga aacgaagctg aacagttggc
    19501 tttgcgttga cctcgtccaa atctcctgat aaaagtttca gatccggttc tatcgtctct
    19561 tgactttctt gtaaaacgac tgcgagatta taagcaatac gatttttgat ttgtgctcct
    19621 tctgtagcat tttctgtttc agcttcttct ttaggtgaaa catgaatacc cgctaataca
    19681 cgtcccttaa agctttttgc tgggattttc acttctatag gtacagttgt ttctgcatgt
    19741 gctgatacat tgatttcctt tttcgcaatg agcaaaacgt cacggacatc aaacggcaat
    19801 gtctcatcta acgttgggtt tttttgacta taatcgatcg ttccaccatc actcgttacc
    19861 gccggattga cagagacctc aaatgttcgt tcttcatctg aagaattgct gataattact
    19921 tctagtgtct gattttgttc cggtgccact aataaatcaa aataaccgat tgctttatct
    19981 atttggttct ctggaaatac cggtttgatt ccaaagtctc ctgctgaatc ctttgcttgg
    20041 ctgattgacg gaaaaatgaa aaatagactt aaaatagaaa aaaacgaaac aaacagtcgt
    20101 ttactttgat tcattgtcca ccacatcctt tcaacaaaaa ctgcggtaaa aaatccttca
    20161 cctatagtat tttcaccgca gtttgttgaa tttatttcat actctatgct actgggccag
    20221 ccacgaggtt ccaagtcaaa tcagccgtga atgttccagc tgctgctttc ggcactttca
    20281 gtgtgatatt tgctggatca taaacagaaa gccatgttcc cagaccttga tcttttgctg
    20341 ctgtaaatat tggtgtcgct gcacttgctt tactcaaccc agttacagtt tgactagttg
    20401 gtccagtgga ttcgttatct gacgtacttt taacagtgga tgttccaaaa tctaattcag
    20461 cgccttgcaa aacttgtgaa ccgtttacaa aatctgaaac cgaaactgtc acgttccacc
    20521 cttgtgcttg gccatctgca cctacacctc gacgatctga tacttggaga taaggtgtat
    20581 cgttttttga agcgtctact tgatacgttt ttgttccgct ttcaatctcg tgtgtaccaa
    20641 atggcaattc gggaactaca tccagtgtta aaggacctgt ctggccagtt gctggatttt
    20701 ccggatctgc tggctctact ggttttgaag gatcagtagg gttaagaggc tccacggtat
    20761 ttgttggttc agtaaaggta atatctcctt ttgaagtcgc ttgaccctca gcaaaagctg
    20821 gtgttgccaa gccgcctaga agaagtgttg aaagtaataa tgtcccaatc atgttctttt
    20881 tcataataaa tcactccttt ttcttagtga cctaagtata gtagagacag tatgcaaaaa
    20941 atcctcatga attcatccgc ttacttgaaa ttatgaccct ttttgtataa aagagaaaaa
    21001 aacaataaaa tcgtttacat gaatattctt ccttttttat taagtatgaa aaaatatttc
    21061 aattttattt tttcgtttca aattattcta ttagtgacat ccttgaacta taaaaatagg
    21121 agtacggcat catctgccgc actcctattt ttttcgtcat ttgtttctta aataaaacga
    21181 ttctcacgca attttatttt tttgatatct tctactgttt gtgttccagc taattgcatg
    21241 accatttcca attctgtttt aaagaaatca aacacttgat ggactcctgt acttcctcct
    21301 aaagacaatc cataaataac gggtctgcca atagcaacaa gatctgcacc tgatgcgatt
    21361 gctttgaaaa catgctgtcc gcgtcgtaca ccgctgtcaa acacgattgg tacacgttta
    21421 tctactgctt ctgccacata ttgcaacgaa tcaaacgctg ctggaccacc atctagttga
    21481 cggccaccat gattagatac ccagattccg ccagcaccag attctaatga acgatagaca
    21541 tcttcttctg actggacacc tttcacatag actggcaaat cagaatgagc agcaataaat
    21601 tctacatctt ttggactaag cttctgtttg gaagatttgt acacagcatc catcgtttgg
    21661 cctactcctg attgataagc ctgaacgatc ggcattggca gtgggaaggt aaacccattt
    21721 ctgcggtctg tttcacggtt tccgccaact gttgcatccg ctgtcaatac gattgctttt
    21781 gctccattac gcttggccac ttcaagaata tccaaattga tcccatcatc tttgctcata
    21841 taaaattgaa accattgcgg tgctttctcc ccgcctgctt ctcttatctc ttctaatgta
    21901 caagaagcgt aagaacttgc tgtatagatc gtcccaaaat ctgctacacc ttttgcagaa
    21961 gctttctccg ccttcacatg agctaagcca tgagcagcaa ctggtgccat gatgattggt
    22021 gcagtcagcg tttctttgtc aaaatgtgta gttgtatcgg gtaattctac atcttttaat
    22081 acatgaggaa taatcagctg atgattgaat gcccgttcat tttcttgata agtaaataag
    22141 tcgccagcac cactgctgat gtaaccataa ccaccagctg gaatcacttg tgaagcggct
    22201 atttctaaat cttccatatt gataaaatcc actattcctt catttgtacc tgcttgatac
    22261 gttttttcca tttcaatgcc ttccctctat aaaaaattga atgaataata tgatagcgtt
    22321 tacacacttt atattactct tccgtattga tacaggcaaa taatctgttt acatttcagt
    22381 cattccagtt gttactactc tgaaagaaat gtttagaaca caaatagata aaaaacgatg
    22441 ggactttgac aaaagtcgtg tcaaagtccc ttttacgaaa tactgtggat gcctattgaa
    22501 ataagtgcgg gttgtttctt tgtatttcaa tcgtttcttg ccattcttcg tttaattttg
    22561 gattaccgtt ttcttccttg aacgcataag gtcccaatcc aaaaagctca gttagtattt
    22621 gattcacgat tccatatagc tcggtgtgat cggacacatg attattgaag atcatctcat
    22681 tatcaccacg tttgaatctc acattcgggc tctcatgatg aacctctatg cagttttccc
    22741 ctttttttaa ctgacggatt tctgaaaaca tctcataaat atcttctcca ataaaacctt
    22801 cagcaagcgc cagactgtcc acaagaccgc ctactgtcaa ctcagagatt atcgctttgt
    22861 tggcaccaag ctttaatgta tagcttgttg cttctactac gccgcatgca ttgcaaccac
    22921 cttctgatag ttcgcttttt ctgatcaatt gaacttcttt cattttctgt tcctcctctt
    22981 agttttctac ttatgtattt tttatcacct gacgtaagtg tattttatcg tcacgatcac
    23041 gtgatttatt cttcagagat tctatttatc tatctaacat atcctttatt cttctacttt
    23101 tctttcttta gcatataaga gatacgcata gtaatcaagc aaggattgtt gatataaaaa
    23161 gaacaaatac cgctattttg atttcttttg actctattac tcatataaat aaaatttatt
    23221 atacctgctc tttttgacta tatcctcatc tgactcctat acttcgtttg tattaaaact
    23281 taggaggaat cattcatgct tacagggcta aacttattaa ataatccttt tctaaataaa
    23341 ggaacagctt ttacaaaaga agaacgggca aaatacggaa tcactggtat gcttccaagt
    23401 actgtccaaa cattggaaca acaatctgtc caagcttacg gtcaatactt aagcaaacag
    23461 accgatttgg aaaaacgtat cttcttaatg aatctattca atacgaaccg gacattgttt
    23521 tataaattga tgggcgaaca tttagttgaa ttcatgcctg tcgtttatga tcctgtcgtt
    23581 gcggattcaa tcgaacaata caacgaaatt ttcttgaaac cacaagatgc tgcatttctt
    23641 tcaatcgacg aaccagaaaa tatcaaagca agtttgaaaa acgcagcaga tggacgcgac
    23701 attcgtttga tcgttgtgac agatgcagaa ggaatcttag gtatgggtga ctggggtgtg
    23761 aacggtgttg acatcgctat cggtaaattg atggtctaca ctgctgcggc tggtatcaat
    23821 cctgcacaag tcttgcctgt atcaatcgac gctggtacta ataacgaaga attattgaat
    23881 aatccattat acttagggaa tcgtcatgct cgtgtagaag gcgaaactta ctacgaattc
    23941 attgatcaat tcgttcaatc agctactgaa ttattcccag aattgttatt acattgggaa
    24001 gattttggac gaggaaatgc tgcaacgatc ttagaaaaat acgaagataa aatcactact
    24061 ttcaatgatg atatccaagg cacaggaatc gttgtactag ctggtgtatt aggtggattg
    24121 aatatatcag gtgagcaatt gaaagatcaa acgatcttga catttggtgc tggtactgct
    24181 ggtgtaggta tcgcaaacat ccttttagat gaaatgatcc gtcaaggtgt acctgaagaa
    24241 gaagcacgcc aacatttcta tcaagtagat aaacagggtt tattgtttga agatacaaaa
    24301 ggattgactc ctggtcaaat cccattcgct cgtaaacgct cagaattcac taatgctgat
    24361 gaattgacaa acttagaagc agttgtaaaa gcaatccatc caacgatcat gatcggtact
    24421 tctacccaac ctggagcatt cactgaagaa atcgtgaaag aaatggcggc tcatacccca
    24481 cgtccaatca tcatgccttt gtctaatcca acaaaattgg cagaagcaaa agcaaaagat
    24541 ttgattgaat ggacggacgg aaaagcttta gttggaacag gtatccctgc tgctgatgtg
    24601 gaatataacg gtgtaactta ccaaatcggt caagcaaata atgcgttgat gtacccaggt
    24661 ttagggcttg gtttgattgc ttcaacagct acacgagtaa atgctgaaat catttctcaa
    24721 gctagtcgag cattaggcgg aatcgttgat gtaacaaaac caggagcagc tatcttgcct
    24781 ccagtagcaa aaatcactga attctctcaa acgattgctg aaactgtcgc aaaatcagtt
    24841 gttgcacaaa aattgaatcg tgaagaaatc acggatatca aagaagctgt tgaatctgct
    24901 aaatgggttc ctgaatataa atctttagaa gattaagatt gttatagtaa aagaacatac
    24961 agaaactttg tatgacgtct aaaaagaaaa aagcgactgc ggcaaaacag cagccagcca
    25021 actactgctc ttttgccgct tctctttggc ttttttcata cgatacagaa taagaaagga
    25081 tctgtaaaaa tggcacaaaa aacaacaacc gcaactgcag ttgaggaaaa gaaaaaagaa
    25141 gggttttggt caacaaaaat taccggcgta agtttgcccc tttatttgat catggtcctt
    25201 gtcctgatca ttgcaatggc tttaggaaaa ttaccgacga atatgattgg cccaatcgct
    25261 gttttggtca ttttcggtaa tttatttcat tttatcggaa caaaaatccc tatcgtcaaa
    25321 agttatttag gtggtggctc cgtttttgcg atctttgcct ctgccgcgat tgctacattt
    25381 gggatcttac ctgagtatgt agtaaaatcc acagaaaact ttgtcagcaa tatgggcttt
    25441 ttagactttt atattgctgc cttgattact ggtagcatcc ttggtatgaa ccgtaatcta
    25501 ttgatgaaag cttctgttcg ttttattccc gttgcactta tttcaatggt cgtctccttt
    25561 tttgccgtag gactcgtagg tatgcttatc ggaaatggtt ttgcaaattc cgttttatat
    25621 atctcattgc ccgcaatggc tggtggtgtt ggagccggag ctgtaccttt atcaacgatt
    25681 tatgcaaatg ttttaggtac ggacgcttct tctatcattt cccgcctgat tcctgcgaca
    25741 gcaatgacaa atgtcctagc tatcattggt gcagcgttag ttgctcgtgc gggacaatca
    25801 atgccaaaat tcaacggtaa tggtaaatta atggaaaaag gcgaccttgg cgatggaaaa
    25861 cctagaaatg taaaaccttc cattccacaa ttaggtgtcg gtttgatggt atcattgact
    25921 ttcttcatct taggacaaat ctgtaactat tttgttccta aagtccatgc ttacgcattc
    25981 atgatcatta tcgttgttat ctgtaaaatc gcaaacctat taccagaata ttacgaagat
    26041 gcagctatca tgttcaacaa cttgattgtc aaaaacttga cagcagctgt tcttgccggt
    26101 atcggtattg cgttattgaa tctaaatgta ttggcttctg ctttgacatg gcaatttgtt
    26161 gtcttatgtt tgacaagtgt tatcgcgatt tcagtagttt caggatttgt cggtcgtttg
    26221 tttggtttat atccaatcga atcaactatt actgctggct tatgcaacaa ctcgatgggt
    26281 ggtacaggaa atgtagctgt cttatctgca gctaatcgga tggaacttat tgcttttgct
    26341 caaatgggca atcggcttgg tggtgccatc gttttgatca tctcaggttt cttgatgcaa
    26401 ttactttctt agtcaaaaaa aatacctgat catcaagtat cggcttgatg accaggtatt
    26461 ttttgataaa aatttacagg attttcaaaa atcttttttg cattttatcg gaatgataac
    26521 cgatgcgttc ataaaatcgg tgtgcttcta ctctgtattc tgcagaatta agtcttattg
    26581 ctgatattcc tcgtcttttc gcttcttcta cgccagtcat caaggccttt ccgattcctc
    26641 ttttttcagc atgtttagac acagcaagtg ccataatatt gaacatcgga tcgctgaaaa
    26701 tcgattcata ggactccgct tgtacatagc cagctgcttt tttagaagta ggatcttcat
    26761 agaccaagaa aaaatttttt tctggctcct tcaacagttt cttcatttgt ctcaccgtaa
    26821 cggttaatgg tacatcatat cctaattgtt ccgcattgat ttctcgtagt gcttctgcat
    26881 ctcctaaacg catttcccgc aacatccaaa tcaccagcca atttttattt ttttaaatga
    26941 atttttttat cacagtatac tccttttttc atttagaaca atatgtttca gtgattttga
    27001 cttgcgttag tctagattct cctaatgttt gtaagatgac gaaagcattg taaagattga
    27061 tcaaaagaac cacgaggaca attacttgaa aaataaaggt cacttttttt ggagacaaaa
    27121 ccctgctaaa tcttgctccc cacaaacctc caataacagc agcggggata acataaaaca
    27181 acatagataa atcaaagcgc ataaagctac ttgttaaagc aatcgttacc aattttgcca
    27241 gttgagaaaa gaaaatcgta gatagagaat atagtgttgc ttcttttatt ggcaatgcaa
    27301 acatcagcat caacaaagaa acattgactg gtccaccacc aatacctaaa aaactagcta
    27361 aaaagcccag aaccccccca catataaggt accaagtcca tgacgtcaaa tgaaattttg
    27421 gctgatgatg cttggtgtag aagaacgcaa aaaccaaggt caataccgtc aaaaaaattt
    27481 ggatcagctg cacatgcttc tcgttttcaa ataactgtaa aaaaacttcg aatacaatgt
    27541 tgccgactac tcctccaaca acagctccac tagataccca accgacaatc tgccaattca
    27601 gtgatttccc gcttgatact tgtcgcacag tcgaaacaat ggacatcgtg aataccgcaa
    27661 ctgttgagta aaaagaaatc cctgcaacag aatgggcgcc gataagatca agaatcggtt
    27721 tgatcaacac gcctccaccc atcccggaaa tagcgccaac tgtgttcgcc agaacgatca
    27781 ccacaaaata aatcagacca atcatcttgt atttcctttc tcttgtttat atcttttagc
    27841 gattgttact cttttctttt attatacagt aaaagaaaca aacgaggctt cgaaagcttt
    27901 tctacttttt aaggaaattt agtgctaaac gaaaagaggt tgtgaaaaag ctgtcctgca
    27961 tcaagtaata agaacagcca aacaaaaata gctcctcata attttcgttt ggttgaactt
    28021 attaccgcag atgcaagctt ttgaacaccg tttaagaaag aggtcgtgag cctgccgttc
    28081 agctccgagt cacaaggaac aatttcaaaa aacagcttct catgtttgtt gaatattgtg
    28141 acttgtgacc gaggagttgg caggagaaca ccgtttaagg aagagactgt gaagtcaacg
    28201 ttttgacctg attattagag aaacaaatgg caaaatagtt cttcatattt cgccgttttt
    28261 cgagcgaatg ccgaggggca gctgattgaa catcgtttat ttggaaaaag ggattgtgac
    28321 aagacgtttg tcacaatccc tttttttata tcttattaat tcattctttt gttctattct
    28381 tcttcttccg ccatgaatga gaaacccata tcaaagaact ataaaggtta tcaaaacagc
    28441 gtttatgact aaatgaatta gagttatcta tcactatttt tcaagcgatt taaaccaaat
    28501 ggcatacaat atggcataca aaaacttcaa taagccgtgg gggtttttaa atttcttctt
    28561 gttctttaaa atcaatgagt ggagctacat aatttgaatc cactttttca aacgtcactt
    28621 tttgcatcga cgaatgtttt ctttcccaag ataacgtaaa tagatttgac tctggactta
    28681 taaagtctac ttcaccttct agtattactt tcttatgcaa atattcctct aataaatata
    28741 gacttgctaa agcatacaac acattttcca aatttgcttc cttataattt gaagaacgac
    28801 catgttttac tctgttatat attttccacc aatctggtgt atcttcaggc cacccatctc
    28861 caaaaggttt tagtgaagtc aatgttaaag aattcataac cctaacacca ttatccaaac
    28921 acattaattc gctagattta ataacagctt taaaatcagt tatgctttta ttgctactgc
    28981 tatcaaatcc gcaaagttct ttgaaaataa tctcacactc cgaaccaatc gctagtagta
    29041 gtttttgata ttcaatagag aatgttttga aattattctc atcgagcatc acaaaatctg
    29101 tggtattaat aaactcattt tctaaatgta gataatactt ccaataaaaa tttgtaaact
    29161 ctgctttgtc cattaaatca cctcttttga attataacaa aaaaaacacg tccacaacag
    29221 acgtgttctt tgatttctac acaatcagct tgccaaaacc atccaatcag tcctagcatg
    29281 cctgtattaa aattgaacgt tcatcatcta tcatctttct tagtccagca tgtttgcaac
    29341 cacacctaca attttcagtc caacaataga tttcgactag ctaagtcttg caaaattcag
    29401 gcagctaacc cttcatttac taccttaatt atactaaata cccacaacgt ttacaagtgt
    29461 aatcattcta agaaatctgt ttagctatga tcgttgtata atctttaaac gccgttcctt
    29521 cattgattga aataatttta taactcttgt ttttccaagc tactttcata tcgtttgtta
    29581 gttcataatc ttgatcgtat cgaataataa acgtcaacgt tccttcaaga atggtaccta
    29641 cactagcaag cacgtctttt agcatttgtg aacgcacatt agcccaacat tcaaatacag
    29701 tttcttcact atccaccatc tgcccatctt catcttttac ccgttttgtc tttttaaact
    29761 tgactctctc agtcaattca tttacattct taatgattgg cataataagc acctctcatt
    29821 tgttgtacta atgcttgtac cgttactggt atccgttcgc tgctggcttc ttgacggttc
    29881 aaataccaat gttgagtaag taatgacacc gccaaatcaa attgctgata attatccata
    29941 tctttatccg ttgcgctact atcaatagca ctttttatat attcgcctgc tgtatcaatc
    30001 aattgttgaa taaagtcatc atcaatagtg tgatcgatcc gcatactttt ttttatgcta
    30061 tccaaaatta ccattttatc tctcctaatg aaaaaaaggc agtgggataa accgccgccc
    30121 aatatttttc tatacttttg gtgttacaac tggcgtaaac tcaatataca ctgaagcatt
    30181 ttgatcaatt ttcttataat cgttgcgaac gatcactgca agtccttgtg agtagtaatc
    30241 gaatttttcc cattgagtcg ttacttgatt tctacgagca acaaagatag attgtgcaat
    30301 atcccccata atcataggga atgttccagc tttaggattg gcaaacaatg tatctgcaat
    30361 caatactact ggcataccga ataatgattt accactaggt gctgtcacat cgggttgtaa
    30421 aatgtaacgt ccatctgaat ctttcaatgt atctaggtgg taatatccgc tttggtttag
    30481 aattaccatt ttatttaatg ctgggtctaa tgccacattg tatagttgtt tcaaatcgtc
    30541 caacgtagca gccgttttct tagtgaatgt ttttaataaa tccatgatat gcttattgtc
    30601 agtgttttct accaatttcg ctaactgatc tttgacctct tgtacaatat tcactgctga
    30661 atcttccaca acctcatttg ataaggcaat cttaccagca cgagtttcta ctttataatc
    30721 aactgaagta aacatttcag cgtcaatatc accaatttca gcaagttcag cttttgttgc
    30781 taacactgct tgttggttag ttgctactgg atatttacct tgtccatttg atactgtttt
    30841 tactgttgca tattgagcta agttataatt tgaacgtttc aaatcaaaga cttcaccgat
    30901 tacttcttcg ggaacaactg ccgctgcatt tacagtagtg actccatcac gcacttcgcc
    30961 ttgtgaacgg atatattctt catacccacg caattctgtt ttttcgttat cgattaaagt
    31021 tttttccatg ttattactct ccttttgtgc tttagaagtg gattctaagc tattgtttgt
    31081 ttgttttgct tggttgttac tcataaacga ttcgtaagaa cgcttattta cttggacatt
    31141 tgatgaatca taagcgggaa cggtcacgac actaatttca ttaagtgctt tgattttatc
    31201 tattgatcgt tcaattgtgc catcttcttt tttgtcgaat gaatctaatc caagcacgaa
    31261 cccaaaggac atagaatcaa caaccccttt tgagatattc tcatacacat catttgaata
    31321 ggtcgtgtcg gttagctctg cttcaaaatg taatcctgta tcatcgacat tcaatttcaa
    31381 cgtacctgct ttgacactag ctagtggctt tgaataatcg tgtccatata ataagaacac
    31441 atttgataaa tccacctctt ttaatgcttc gggtgtaatc acttctacaa agccgcctaa
    31501 atcttttgac ggttgcccga atttcaacgc atagcctgaa atagttttgc cgtctgttgg
    31561 ttgtttttca ttttctttct ctactttggg agaatcggct gttagctcag cttcttctgt
    31621 cagccgtttt tccttttctt cttcattatt caactggtgt aactccttcc tgttctttta
    31681 attgatattt ctccaacgta tctaaatacg taaagttcaa acttgctagt aaacgatcgc
    31741 caccatccat ggggggtagc cccattttcg accgcccctc attaatcgtg agaagtgacc
    31801 ctttgacctg atccaataca ttttttactt ttgtttcagg atcagtctct agtaactgat
    31861 cggaattaaa gcggatattg gtttcaagtt tcgtatctaa ttcactcaca aacacattaa
    31921 agtaatgaat cagcgtactt tggatatact ggagattact ttgaacggtg ctagaatgtt
    31981 cattttcaac gcctaaacgc tcaatcggta caccaaacgc cttggcaatt tgttttgtgt
    32041 tccaatcatt ggaattgata agcttcaaaa catcggtgtt tatttctaat gttttgtagt
    32101 ccattgtttc atcaagaatg atcgttctaa gagcattatc tccactactt gaaccgttgg
    32161 cttcttcaaa cttttcacga attgcgttct ttgctgatcc gtctaaatct gacttatgaa
    32221 ccttcaaaat acctgaccca ctgacaccac gagtaaagaa attgtgcaat gtgcggttgc
    32281 cagcttgttg aattttcagt tcatcacgta acgcataaag tggtggtaat cctgttaaac
    32341 catcttgggt gaaatatttg aagtgcaaaa tatcgctaga cttcacacgt ctttttttat
    32401 caccaatctg ataagacaac gtaccattat ctaattgagt aaccgttaca cttgagttag
    32461 gtaataagtg aatttcttct accttttcac cgttgcgttt aatctctgca aagctattac
    32521 cgtttagcaa catattgacc gccaaagcaa actttaaatg ccaaccatcc atttctgaat
    32581 taggtttctc gtttagtaac ttcaccagtt cattatcagc ttgtggcata ttgtttttga
    32641 ccaattgaat cggacttgaa gcaatatcac tagcaataat tcgaacggct gcaaacacat
    32701 cactatttct taatgcacga acgcttgtaa agctggtggt gtaatcatcc gattggattg
    32761 ataccacatg ttgtaggaaa ggatctcccg ttgtattttg tctcgcttta aaaaatgcca
    32821 tcttttaacc tcccttctgt tctgtattta gcatgaccgc taccccaata agcactatgc
    32881 ccagcgctaa caagccatag tagacatttg ttagtaaggt gatagcaacc aacacacaca
    32941 ccaatccaag aagtaaaaga acggtatgaa tgtaattaga aagaaaattc ttcacttgta
    33001 taaaattcat tgtctgcttt cgctccttcc gttgtggtga agtaatccat tgcaaacaca
    33061 taggcattga ttaatgcagc tattggatca attttgttac tgttctttga tttattaatc
    33121 tgaatgccgt tgttatccgt ttttaaaata gcgttgttca ctgcatgggt gagaatcgta
    33181 tttttattgt gaataacgtt gccttcataa acttgttctc taaaagttcg ggtcggaacg
    33241 tttagagtaa tcgttccttg tcttacttct aacattgggt agttggcttt ttcagcttta
    33301 ctgataagcg aattagcgtt atacgggtca taacaaatcc ccatacattc caaatcattt
    33361 tcttgaatca aatcttgaat aaactgaaat acttggtcat agtccacgat tccactttct
    33421 aattgagtaa tggaacactc accagctttt tctagttctc gataaggcaa accgtcgcgc
    33481 ttttctttgt cttgaagccc atatttggtg gctacaaagc tatgtgaatc acaataaagt
    33541 tcgccgttat ctagcggtac gatccatgaa acgctagtta aatcatctgt tttagataaa
    33601 tccactccga tataaacggg cttgcctgta atatcttgtg gttctacttc ggttgcctgc
    33661 cagtcttcag caatcatata gctgtcctca ctcgcttgtc tccataaatt gaagtttttc
    33721 accaatacag aattaaggtt attttgtttc aaagcaaggt tcacatcatc ttgaatggtt
    33781 ggaatcatta cttttttgat ttcttcactt tcaaaaatcg gattggcttt gatccatttc
    33841 tcttgatcgt gaatttcttc gggatcgtcc aattcccata tcgctataaa gtacctgtcg
    33901 gcttgttctt cgccttttag cacacgatct aacaataagt attcctcgta cataggaacg
    33961 tttaaatcaa gcccagcggt actaataaca cacaataagc cgttcttttg ttgggtcatt
    34021 cctgacttaa tgacgttgta cgttttacga gtttttgctt cgtgccactc gtcaagaatt
    34081 gcggttgttg gtgcaaaccc atctagcgtg ctggtttcac tagccagtgc catagcgaac
    34141 gaattagagg gcaagtgctg aatcttagag ttcataattt tcagttgtgg tcttaaaaac
    34201 ttactagact tgaccacgtt tctaagtgaa ttagacagca tatcatagcc caatttagct
    34261 tgtttcaaag cgttacttac aaacaatact tgccttgctt ctgctggttc ttgttccata
    34321 atcaacgcat tggcagccat gccacttgcg atatacgttt tcccattctt acggctcata
    34381 ctggtaaacg ctcgattgaa tcgcctgtaa ttcccttctt tagtacgcca gccataaaga
    34441 ctgcctagaa tgaatttttg aaatcctaac atcttgattg ctttaccgtc cgtagatggt
    34501 agcaactcaa tgaatttaat cgctttggtg gcttgttctt catcgaacac ataagggaag
    34561 ctatctgact tagaacgctc caaatcgctt atatgacgct cacacgcttg gataattttc
    34621 ttgggtgcaa tcagcttacc tgataggact ttctcaatgt aatcattcat gaattcatca
    34681 actctttgaa cgggtcttcg ggttcatcat ttttaacctt gttcaaagct agttttgatc
    34741 gtgattctaa ggtcatacct agtgaggtgg cttgtttttt caaatcactc atagcttgtg
    34801 attgaacccg aaccgctgga ttggctttct ttactccgtt ttcgcatgtg ataaacgtac
    34861 ctgattttct tatctcggct tcggctgttt tcattcgagc aaaggctaaa caataggcta
    34921 ccaatgaacc ataatctgct tcactcaatg gataatcttt ttttaatgtt ggtacgatac
    34981 gattccattc acttctagcg ctcgctgcca tccagtcagg gggcgtgata tttattaatg
    35041 gttgctgctt gaacaattct tctctagcgt ccacacggat tgctttttct tcacttgata
    35101 tattgccttt tgtatcgtgt aatattttag ggtgtcccat gttgtcctcc tttcagacaa
    35161 aagaaaaagg aacgtaagca attaagctca cattccttcg tttttcgatc agaatttttc
    35221 tttatctaat ttatctatat aaatgatttt tccgttctgc atttgaatgg tcacttgacc
    35281 aaaatgaggt aactcaatgg tgcgctgttt ccctgtttta tcagtaataa caattgtatt
    35341 tttcaataaa tctcctactt tcattatata ctttttcact tgtgattaca agtgtaatcg
    35401 ttatttgtaa ttacccttat gccttttcac aacggttatt tgtaccaaaa tgagtaggca
    35461 tcgattgtca gtaagtttca cactatgccc ccttaactca aagggtactc ttttctcgtc
    35521 tttgtctttc attggctgtc ttggaattat ggtgtgcatg gcataaagaa cgaaaattag
    35581 tttcatctaa ccgtctattc caatcatctt ttagttcaat tttgtgatct acaacatcag
    35641 ctttccttat caagccttct tctaggcaat cctcacatac tggatgattt aaccgataca
    35701 agtatgaagc ctttcgccat gttctacttt gatagaattg aaaatattta ccttcgcttt
    35761 gctttctttc ttcacgctta attgccgttt gctttgcttt atgcttccca caatacttct
    35821 gcctataatc aatcaatgtt ttacatccag catgattaca ttgtttttta actgccatag
    35881 attaccaacc aaagcgatct cgttcgtcag aatcatcttg ttcccatttt gatttgtatt
    35941 caatataagg cgaaactatc ttcaagcacg ttccgtcttt aaaattaact ttagtgattt
    36001 tatcttcctc aaaactaata aagtctacat cttcttgagt gtttgaatac tcaatgtgtt
    36061 tctcaccatc gaagtatcta atactttcca tatgcataat tattctacct ccaataaatt
    36121 agttatcaat tcatcatctg ttagtagcaa agccaagaac ttatcatgga tgtttaaaaa
    36181 caaattatcc tcattcgatg taagctctcg ttgtctcgct cgatcatata ggttaagcag
    36241 acaattaaat tcatccatta gctcacctgt atcatcatag ttgccactat ctaccaatga
    36301 tcccactact agcgattgac accacgctac tgactcctgc agccaatcag gttcttcttc
    36361 cattatcttt aatacttctg gatcaaatgt ggaataatct tctgttacca atcccacact
    36421 aaatgccagc gtgttcatta gaaaccgatc catttcatct gtatattgaa agttcggtgc
    36481 tttgtttgtt gaaataatat tgagcattta ctttcctcct tgattcgtaa cacgtggtaa
    36541 cacctacgta acaggtaccc gttaccactc aatcccaacg gggacaaggg ttctagcgtt
    36601 ttggtaacag gtaacgggta aaatccagta acattattcc ccagcatatt agctaactat
    36661 ttcaaaagtt ttaaggaaat aaggtgttac cccgttacca aattgctgta tcccttgggg
    36721 cagtaagggt aaactagtaa cgggctaggt gttactgacc cgttactacc cgttactttt
    36781 tgtactttcc agctcgattt ttattttcat aggcatttga cttattgtaa aatcctcgtc
    36841 gtttatttct ttttggcagt tgcttccgtt cccaaccagg aatactgcta ataatcaagg
    36901 caatcttttt agtttctgca tctgatcgac cattcaataa atcctttgct tgtttatcaa
    36961 aaacagcttc caaaatatca gcggtgagta cgctatcaac taaataaaac tcttgttgca
    37021 tagtagctcc attatagaaa tgctgtaaat ttttctcatt acatttactg tcaggatagt
    37081 tctgataata agaacgtctc gcccacgctg gagcttcttc ccatttatac gggatttcca
    37141 tttccaaata tttagtgatt gcttctttaa ttggattctc catcttggca tcctcttgat
    37201 agtcttttgc aatttctaag acttctttat cttcatcggg actaaaatag attcgttgtc
    37261 ctttatcaaa aagcaccttt gcttcagcta acacttgaag aaaatattca tcctttgttt
    37321 taaacggatt catctttggc ttattcttac aaggcaaagg ataaaaacgg cggtttcctg
    37381 tatcatcttt caaatactgc ccatcattcg acgttccaat aaatacacat tgccttgccc
    37441 aagctatgac attccgacca taaggaggtc taattttatc gatcttggca ctgatgaagt
    37501 tttttatctg ttcaatttta gttttgttca ttgaagataa ttctccaagt tcaataatta
    37561 cattgccttg aagctgcata taatcatctt tcttttcacc tagcgaatct aatgaatcgg
    37621 tgaaaaaatc atccgtgtaa agtaatgctg gaacggtact cttaccaatc ccttgcggtc
    37681 catccaaaac tggaacgatc tcaaacttta ttcctggttt atagatacgt gcgactgatc
    37741 cgactatcca acgttttgtt acttctcgtg tgtaaaggtt gtcgtctacc cctaaaaggt
    37801 caataaacag tgtttccagt ctaggctgtt gatcccattt aactttttcg atacgttctt
    37861 ttactgggtt gaaaacattc tttctagcca catttactac tgctttgtgt attttgttgt
    37921 catcaaaaac tacattgtag ttttcttcaa tatatgccgt taaggcatcc tcaaaactgt
    37981 cttcccattc tccagcggta cgattgatcc aaggagaatc ttttaatagg tgaatgtatc
    38041 cgctaaattc gttataagca attgttccag ctaaattgct atcattggtt aaaatcaatt
    38101 ctgcattcac aacactgtta cttttaatct gatcgtcttt attgcatctt aatcgtgaca
    38161 tccaggtttt caattcaatg atattgtctt cacgctcgct ggcttcggga aagtctaaaa
    38221 tactatctaa tttatgctta tgagccatga gctttccccc tcaaatcttt tttaatcatc
    38281 gatcgaataa tttgattcac ttctttatct tttagcggtg gttcattgta cgcatttgct
    38341 gtataaatca attctgctaa agtttgatta tctacaccgt gccatagtaa ccaaccgcat
    38401 aacttagtta aatgatcgtt tctactacct tcgccagcgc cttgaacaat catatctaat
    38461 ttttttgctg tccctgtttt tgctacgggt cggtattgag tctttatttc ttgcggtttt
    38521 tttagcagta ggttcactag ccaatcggga gctggtgcaa tattatttag agatacgttt
    38581 tcaataggtt catatgctct cccaacactt cttgaaataa tcatagttgg cgctattgga
    38641 actcctttag tgataatatc aatcccgctt aaacttttac ctttatcatc acgcccgaag
    38701 atatcagcaa atgcacctgt ttcttgttgg ataattacac catcaggaat tttaaagaag
    38761 aaatggattc ctttacctgg tgtgatttcc gtataagtag aaggaaatgg atcatacatt
    38821 gaagcaagtt ttttataatt ctcaacgccg tttcgtgttt cagaatgttg atctaggtca
    38881 actaccacca tttgatgatc ttcaagcatt aacccaatat ttctagttgc atcttccgtc
    38941 caccattcat taatttgatt agaatcgtta gttgcatcat tccaaccact agagcctttt
    39001 attggaattt tagttccagg agataaggga taaattgacc atcccgactt ttgtaattcc
    39061 gttgctgctt gataattatt tgccaataaa cctctcctcc tttttcaaaa tactggtata
    39121 aatcattcag acacctccat gagcttcaac tgctcaagtt cgtatttcaa cccatcccga
    39181 acaaattcag caccttttaa ttgattctga tactttaccc atgtattaaa tgttttcacc
    39241 cttgcttctt gcatatcagt aatgtttaac catgcggtta aaatctgatt ttttagctcg
    39301 ttgatttctc gacaaattat tttgtgttct gcatgttttt tgagtacata caaaactgtt
    39361 agtttttcat tgaatgaatt tccaaagtag gttttcccga tattattttc tagttcagcg
    39421 atcccttgat taatttcctc taattcaagg ctatcgagtt ggtttaatag ttttgttttg
    39481 tacatctact tatgccctcc agttcttaat tgatagtcgt actcgtcata agcagtgaag
    39541 agatataacg ctaatcctgc aaagatagct atttttgcaa ttaatggtaa taagccgaaa
    39601 attccgccga ttaaaatgct tcctataatt aagtttcgtt tcataatggt tccctccgat
    39661 tttttaatat ggtataatcg gaacaaagaa tatcgggttt tatcccaatt aagttgcctt
    39721 tatcctgtcc gccaagactg ttatggataa ggctttttct ttgttctcga tcatgttaat
    39781 gctcctaagt tgtctgcaat tcagcagaac gattataaat tttctcactc actgaaaact
    39841 gcaacccata tttttcttta acagtcatta attctactgt ctcatctaaa ataggttcac
    39901 gatcaaccaa catttcagga gtcatatctt tcttttttac cattttggaa tgaccataaa
    39961 tagttgatac agctttattg gctatcacat tcgctttaat gtagtctact ggttttggtt
    40021 cagtaatagc gtggcttaat ttagtcattg cttctttttg gtgttctttg tctagcatgc
    40081 ggaatacttg aaagccttca agtcctgtgg actggcgtag ttctttgatg atgtcgaaaa
    40141 tccagtcttg aaatgcctcg gcttcttttt tacggctttt gaatgccatg cggtaaatat
    40201 tttttttcgt tgatgatgtt tacatcttgt gttctgccca atgaatcgat gaccttacta
    40261 gtagtaaccc catctttagg caaagagtga atggctctag taacctgttt aagacctaac
    40321 gcttccgcaa catctttcgc cactgcccac cattcatcat taatatcgac aaatcttata
    40381 atgtgtccgt tccaaatttc agttttcatt caacgtcctc cagttcaagc cctagcaagc
    40441 tcgctaacaa ctcaacttgc tgatacaaaa tttcttgata ctcttcaata gaaagtcgtt
    40501 ctttaaactc tgcttgtact aaatcgttca agccacgcaa tactccgctt accgttggtt
    40561 cttgtggtag caatttttga tagtccattt gttcgtacaa acattcaaac gtttcttcta
    40621 gcgctttgcc ttccaagttt gctaattctg ccgctgtgtc ttctgtaaga attgttgata
    40681 atactttttc gattgcttta ttttgtgtcg attccattat tatttcctcc tattaatccc
    40741 tttgccccca cggcttgcgt ttatttttgg tattcttcca taaagcgatc acattcatct
    40801 tgtgaaattc ttacgactcc atcaactata atcaacttta aaccgttagg aacatatttc
    40861 tgcatcatag tattgtatga aacgttcata tacttagcag cttgtgcctt gttcatatat
    40921 tttggaaact ggtacttttt ttctaataat gaaagtaacg ttccttgagt ttgctctact
    40981 tgttgaacaa ctcgatcgtc aataatttta aaagctggat catcaagcgt gagtttgtca
    41041 atttttaatt ccatatttat cccccctcgt tagcatacat ttctatacaa agattttaaa
    41101 aaaatgcaag aggctcttga atacatttct atacctctta taaactcaat ataccatcat
    41161 accttttcat ttgcaagaat tttaacatac ttttttgaac ttttatgttt cacacatatt
    41221 taaatcgtga tatagtagag aaaatatatg aatggtggtg aaaatgtggc tagaaaaaaa
    41281 taccccgaag cagtggagac aggacaaaga attagactgg ctagaattga aaagggactc
    41341 tcaatggaac aacttggagg taaattatcc ccaccggcca gtaaaggtgc cgttagtaat
    41401 tgggaaaatg gctataatct tcccaataac accaggctta aacaactttc aaaggtatta
    41461 gatgtatcca ctacctatct attaaacgga tcttatacat taagagatat gcatatgatg
    41521 cccgaaatta agcgaaatgt gcttgaaaag caattgaaaa aaactattga aaaaaataac
    41581 tctataattg attctaatct ttctaatgct atcaataaca tcgaagaaga taacctgact
    41641 gtctcacaga agatttattt aacaaacgca ataaaatatc ttaaaacagg atctcgaatt
    41701 gaatttcctg acgggagtac cccaattgct tatctcgcag ctcttctaaa tacgctttta
    41761 cgatatgact cattaattaa tgattcagaa aaaaatacag atgagaaaaa agagtatcaa
    41821 gaattttatg aaaatgatct tctaaaagag ttcacagctc ttgttactga gctaaataaa
    41881 cactattcaa aataataata aactgcctcc tccaaccgcc cccacggctt gctacactat
    41941 ggagggaaaa ctattatggc aacattcaag caatatgaaa ctaaaaaagg taaattttgg
    42001 ctctatgaag cctatcttgg aatgaacaaa atgactggca aacctgataa ggttcgtaga
    42061 cgaggttaca aaacaaaaaa agaagcccag cttgccttgt cacgcttgca agtggactac
    42121 gataaaaacg gtattaaaaa agcgaacaac gaaacgttta aagaagttta tgacttgtgg
    42181 ctagaaacat ataaaaccac tgtccgagaa gccaccttca tgaaaactga aatcaagttt
    42241 agaaagtgga ttcttccaaa atatggaaat cttcgtgtga atgaagtcac ggtaaaaaaa
    42301 gcccaacaaa ttgtaaatag ctgggctgaa actactgacc aatacaaggt acttcattca
    42361 acttctaagc gtatttttag ctacgctatc aatcttggga ttattgagac taatccacta
    42421 gacaacgtat taatgcctaa aagaaccacc actaagcata aagaaaaggt caaagtttac
    42481 agtaaagaac aactgatcac cttgtttgat tacctaaaca gcaaacctga aacttatcga
    42541 aacgactttg ataaaacgtt actacgcttt ctcttttata gcggggttag gatcagtgaa
    42601 gcccttgcat tgaattggtc agacattgat tttcaagaaa atacggtcac catcaataaa
    42661 acactaagcc aatccaaaaa tggctataaa atcagtgatc ctaaaactga ttgtagtgct
    42721 ggggttcttc cactagatga aagaacaatt tctatattaa aaaaatggca gattaatcag
    42781 cggaaatata tgctgacact tggtgtaact gatccgacta tgattttttg tggtatctat
    42841 aaagaactaa tcacacacca cgctatttat gcaagattga ttactatttg tgaaaaagct
    42901 atggttccat ttctcggtgt gcatgtagca agacacactc atgcttcaat gctcttggac
    42961 gctggagcta ctatggtaga agttcaaact agattacggc atacaaaaat tagtcagacg
    43021 atcgattgtt acggtcactt ggcaaaagaa acgaaagaaa agactgttga aaaattagta
    43081 caacacttaa atattgacta gatggcatac aatatggcat acagtaaaaa ataaaaaaag
    43141 gagaaaccct atcatatcaa ggtttctcct agctttatag tctattcttc ttcttccgcc
    43201 atgaatgtat tgaatacttc ttcaatcatg tcccattctg cgtctgtttc gatttgttct
    43261 aactcgcctt ctgttccatc ttcgttttcg atgtatgcat aagcttgtaa ttctacatct
    43321 tcatcttctg aaacaccagc aggatataaa agaacatagt tacgtccaaa ttcttcttgt
    43381 ccgtcaactg ttagtaggat ttcatataat gtttcatttc cttggtcatc caccaatgtg
    43441 atgtgttcgt gtccttcatg gtcgtgggaa tggttatgtt ctgtcataag attacctctt
    43501 ttcttttatt attaaaataa ttgcttacct gagccgtcta aataattttg taagatcatc
    43561 acagctgcta atttatcgat gacttttttt cgtttggctc ttgaagtatt tgcctgctct
    43621 actagcatac gttctgcctg aacagtggtt aatcgttcat cttgataatc aactggcaag
    43681 gagaatagtt ctttgatctt ttctccgtat gacatggaag cttctgccct tggtccgatg
    43741 gaattgttca tatttttagg taatccaact acaaaccggt ctacttcata ttgtgctact
    43801 aattccttca accgatcaaa gccaaactct tcttctgctt cattgatccg aatgatctct
    43861 actccttgag ctgtccagcc aaaggggtca ctgatagcaa cacctactgt cttagaaccg
    43921 acatccaagc ccattactct cataaattca ctccatgatt tgagaggtag tccttgacaa
    43981 ttacttccat gatctcatcg cgttcgtgac ggcgaatcaa atttcgagca tcacgataac
    44041 gaggaatgta ggacgggtct ccagaaagca agtagccgac aatctgattg attggattgt
    44101 agcctttttc ttccaaagcc cgataaacaa tcgctaatgt ttcgctcact tcttttttgc
    44161 gactatcgtc aaaaccaaaa cgtacggttt catctgtaaa acccatgatt ctacacctct
    44221 ttcccgcaag gtaattccag cttaccttct acaaccttat tttactcgaa gaaagggaaa
    44281 actacaaaca aatattccaa acttccgaat aaattaagaa acactatttg tatgtttttt
    44341 tccttttttc tgtagcttta tcaaaagtac tcttttcata aagtatacgc tatatttctt
    44401 tgaatgtatg tttttacaca attttttcat aatattcata aaaaattcga atagctgcta
    44461 ctaatttttt gtttttgttg cttgtcctgt ctcataattg atcgtgtagc catcttgaac
    44521 attgtagata aagacattga attcaatttt tttgtcttca atgctttctg cttccaattg
    44581 cactcccctg gctaccagtt cattcccctc aaaatgagga gtgacacggt agcgtacatg
    44641 atgatttgtt tctttgatat atgccgcaat atcattttcg tgagcaagca tgtatggagc
    44701 attcaacgaa cgtgtccctg tcatcaagtt tttaatgttg ttattttgac cagtcagctg
    44761 gaaaccaatt aaatggctgc gattatataa ccattgcccg tcacttaatt tcttttgttt
    44821 ccaacctgtc gggtcaatat acaaaggctc tctcttttca gtagggaaca aatcttttcc
    44881 aagcatagca ttggcttgtc ctactctgtt caatttatca atatttgaat agctttccca
    44941 tgttcctttg gaaaggctaa gatcctcttt tgtaaattcc ggctgattcc cattgatttc
    45001 tatttcttga tgttttccat catattctgg cacatccgct acttgagaag cttgtggtgt
    45061 ggaatcaaaa atagttgtaa tctgctgaaa gatatctgaa tctttttgtg tggtggaaac
    45121 accgaatgcc cctgcaatca cagcagcgac gatccccacg atcgccttgg ttgttttttt
    45181 gctcatttct ttactccttt actaacagct ccctaaatct taacatatgt tcccctataa
    45241 ataaatacta gaaagaaata gaaacagcaa aaaataaaac ctgttttaag atggcttaaa
    45301 aatacaaaaa agagacggat tcctcgtctc taatcagtca ccactctatc tgtaaggtat
    45361 ttattattat tcaaaaattt tcttcatact caagacaata cactgatttc acaaccgctt
    45421 ggtaaacggt gcgcaaaagc ttgcatctgc ggtaataagt ccatccaagt taaaaacata
    45481 agaagttgtt tttgcttggc tgttcttatt acttgttgca gagcagcttt ttcacaacct
    45541 attttaagcg ggtgacggga atcgaacccg cgacatcagc ttgggaagct gggattttac
    45601 cactaaacta cacccgcaat acaaaaacag tatacgcctc ttttattcct tcctcaagtt
    45661 tttttattct ttacgcttct ggtatgtttt gtagtaaaat aaaactaatc aatcaattat
    45721 tggagaagat gctatgacgg gaaaagaatt agatctgttg ctggacactt gtttactcgc
    45781 tgggaaaatc atgatggaaa gcaatgcgga gatgtatcgg gtagaagata cgatgagtcg
    45841 aattgcttta gcttctggaa atttccgttt ggtcagctat gtcactcaaa ccggtctctt
    45901 tattggtctt gatcgtacct cgaccatccg aatggaacaa attaccaacc gttcgattaa
    45961 tttagaaaaa gtagtaaaag taaatgatct ttcacgtaaa tatgttgctt cagagctaac
    46021 attagaagaa ctttactgcg aactgcaagc aatcgaccga gaccgttctt tctttcctgt
    46081 ctggttgcaa atcgttagcg cggcagtgat cagtggaaca attatggtgt tatttggcgg
    46141 aaagatgacc gatttacctg tgactttagt cattggagga ttgggatacg cagcttatct
    46201 atatagtttg aaatttttta gaatcaaatt tttatcggaa tttttatctt ctttattgat
    46261 tggcatagcc gctatctaca gcgtacgttt tggcttagga agcaatcagg atctaatcat
    46321 tatcggatgt gtgatgcctt tagttcctgg agttcaaatt acgaacgcta tccgtgattt
    46381 gctagctgga cattatgtct caggagtttc tcgcggaaca gaagcgatga tgactgctac
    46441 gatgatcggt tttgcgattg cttttatttt ccagcttttt tattaggaaa ggaacacaag
    46501 tatggggacg atatttattc agttttcttt tagtttttta gcgactgcgg catttgccgt
    46561 tattacaaat gtacctaggc gttcattgat ttgttgtggt ctttctggtg cttttggctg
    46621 gatgatctac tggatctgtg ttcaaatagg cggatctgct gcttttggtt cattgcttgg
    46681 ttctttagga gtagcattca tcagcgatct tttctctaaa cgtttgaaaa tgcccgtaac
    46741 gattttcaat attcccggga tggttcctct agtccctggt ggtttagctt atcaagcggt
    46801 tcgaaatctc gttactgaat cctatcgaga agcggctcat tatgcggtcc aagcaattat
    46861 gattgctgga gcaatcgctt taggtcttgt attatcagaa gtctttaacc ataacatccg
    46921 taatttcaaa gtaaagcgtg acgcaatcat gatgaaacga aaaaaacggc tttttaaata
    46981 aacgaagtgt aacaaagaaa aggttgtgaa agagacgttc agccttgagc gatgacaaaa
    47041 tatctcacaa acattgcgac aagtaaccgc aggagcaata agaagtaatt atgagtatta
    47101 aaaaaagttt tgtaaaaata gcttctcaca tttttacata aaattgactt aatactgaga
    47161 aactgacttt tgaacaccct ctatctgtaa aaaaggggct gcgacatgat ttttgtcacg
    47221 gcccctcttc tttattcaaa ttttttccaa aacgttcgtt gataataaac gatccataga
    47281 gcggaaagta ttagaactaa accgatcaca ggaatattca ctaaccaaaa tggataaaac
    47341 aaagccaaca ttccgtataa gacgataaga ataatactga tgatcaatga acccatcata
    47401 gttgcgacta aacccaaact tcctgaacct ctgttaaata attggttaat attggtccag
    47461 ttcagcagca gcaaccgata atctctagcg aaataacgta gtgacaataa gtagcagccg
    47521 aataaagaac caaatagcaa gctagggata aaaaacaaag gcagctgaaa agacagtccg
    47581 cttaataatg cgatcccacc agttaaaaaa ctctgcaata tccatccgaa tctgaacttt
    47641 tcttttaaat attggttcat agagattggc aaagaacgga taaacagaaa attttcttga
    47701 tccaaagaaa taagattgct gataaaagaa gtctgattaa ctgttaagaa agccaatgcg
    47761 atccctacca ggaaaacaac accgattaac ttattatcta aatcagttaa ttttatttcg
    47821 cctcctaggg caaaagcaag aataaaaatg attggagtta acaaggaaga agaaagaact
    47881 tgcataatca aattaggttc ttttactaat tgagcattgt aactaaataa aagctgatgc
    47941 acattttggt tctttttatg ggttcttttt attttgaact cactgtttga atcagtcagt
    48001 tgctctgtaa gctttggtac tatcagctgt tttacagcaa ggaaaaatcc cagagccgtg
    48061 atagctagta ttccccaacc caataaacct tgttgagaaa gtggctgact ggcagcatca
    48121 tagaatggca ataatatcga aatcggatgc cgatctgtta actcattttc aatagtcccc
    48181 gtttgatgat tcatccacat gattccagca aatgcgatca gcatcgagct gccaagcaag
    48241 atactagaaa ctgtttttct atgtttttta aacactgctg ttcgagccaa accaaaaaca
    48301 atcaaactag ccagacaaaa aagaataatc aaaaatagag aaaacaaaag gattgagata
    48361 atgatagtaa gcaaaatccc tagatcagct cgccatccgg ttaaaataaa catgactaga
    48421 agcggaaaaa caaaaggaat gatggtcaaa gcaactacca aaatctttgc tgaaaaaacc
    48481 tgttcttgtc caaaaggcag aggcaaaaat acttgcaggt catttccttc aaaaaagata
    48541 ttataaatga ctgatatact ttgagttaaa cctaacatac caaaaagtgc cacgtaataa
    48601 gtaaagaaac ctggcaattt aacaaagttc atagcaaaca tagcaaatcc gtaaatcagt
    48661 aaaaaaatca gccctgaaaa aagattttga gacaaaagat agatagttaa tcgctttccc
    48721 ttttttcctt tctctcttgc tttattcgtg agctgtggat taacatataa aagattaact
    48781 cgaattaatt ctaataattg tcgcttatac atacggtcca tctcctgtcg cttgccttcc
    48841 agccattttc aaataaatct tttctagcgt ttcatcaggt gagccattca ataattcact
    48901 aactgccccc tgataaatca attcaccttt cttcaaaata gccagtttat cgcataactg
    48961 ttgtgcggta tccaatacat gtgtagaaaa aatgactgtt tttccttttg cggcatgagc
    49021 cttcatcatt tctttcaaat caaatgctgc ttgaggatca agtccttgca aaggttcatc
    49081 caatacccaa atatctggat ctggcagcaa cgtgccgatc aaaatcgttt tttgacgcat
    49141 tccatgtgaa aaacttgcga ttgtttcatt ttgatgacta tacatatcaa aaagcgctgt
    49201 caattctgct aaacgctttt cttttttttg tgtgtctaat tcataggcag ctgaaatcaa
    49261 gtcccaatat tctccagccg tcaattgtaa aaaaatatct ggggaatcag gcacataacc
    49321 gattttttgt ttgatactca atcgattttc cgtcaatttc attccatcta ctaaaatcgt
    49381 tcccgatgat ggttcaataa tactaactaa acttttaatc gtagttgatt ttccggcacc
    49441 attatgtcct aaaaatccaa aaatttcccc ttgtcttatc gagagagaca agtcttttaa
    49501 tgcttgtttt ttcccgtaac ttttacttac attgatgaat tcaatcattt ctgtactcct
    49561 tttgtttgtt attacttttt attgtaccct tcgttattgg tggagtaaat gtcaaaaaga
    49621 gtgcataaca aaaaaggata gaaacgacta ggctgctact tgggttgttc tcttctacag
    49681 gaaaacactc ttctaacagg taagatatga gtctttgttt tctttaaaat gattcatttt
    49741 ctatcttttc ttgcataaaa ttctttagtt tatcaatact tctctttccc atctctagtt
    49801 gttctccatt tgcaaatgtt actatttcgt ttactctgct aatagatgta atgttttcag
    49861 tattaatgat ataagctttt aaatctttac ataaatactc atattcgagt gattttttat
    49921 attttttaat tgtgccgttt acgagaatct cttcatcttt caatactagg cctattttat
    49981 ttttataacc tggcatgctc attagataaa ggatttcatc gtaatggata tagtgatcgc
    50041 tattaccata acggacagtt gtccaccttt ttttcgtagc atgttgaaca ggatagtttt
    50101 ctttttcttt caataagtaa ctttggatgc tttttttatt tttttcataa gtgaattctt
    50161 ttatcaaata accactaggc gtaatctttc gattaataac agttattgct ttattcggat
    50221 gagacgttag ataaacaatt ttacactttt cattcttttc tctaagcatt tcgcctagtt
    50281 cgataccgct ataataggcg ttcaaatcga tgtctaggaa aaaaatatct gaggaataga
    50341 tttcattatt tttaatgaat tcaacaaatt gtataacgtt caatccctga acgatctcaa
    50401 atttccaagg acttaataaa attctggatt cttccaaaat ttctactagc attttttcaa
    50461 aaaccaaact atcatccaaa ataaatatac gcgttaccat aaaaagtacc tccactcgat
    50521 attttactat caaaatcatt tcatacaact tttcaacata catgttagga ataaattgta
    50581 attctcttca caatcttttc caacaccttt gaaaccgata tcaaatactt tcaggatgct
    50641 gcttctaaaa taaatatcaa acaaatgaat acatcatgca aaaaaagcca gacaaccgac
    50701 gtccttgcgt gtcagctgtc tgagctatgt ttatttattt tgttctttta aaaagaacga
    50761 tacacatact gatttttcgg agcagagact ttctcagcgt ttgtaacaac tacagatggg
    50821 atttcacgct tgaatggttg ataatagtct gattggatgg ttccttctat tttataccat
    50881 tcatcatttt taaccgttac tccttccggc atatgcgtca acaaaccaaa gactcctgaa
    50941 tctgccacac aatggataat gccgaatcgg aacaagaaga tatctgtatt gctatcgttc
    51001 ggtgtttggt aaacaaatcc ttcatagctg atttttttgc caatgaattc gctagggtaa
    51061 ttataaatta gctccataac ttctaaatag ttttcatctg tgatcttgat agtttgctta
    51121 tccccatact tttctttcaa ctcattcatt tggtctaagt agtctgattt gttgaaataa
    51181 atactggtat ccggctttaa gtattgtgtc tgcatctccg gatcccctac tgattcttta
    51241 cttactggga aattaaatcc tttggcttct acgatcgtag tgtcgagact aactgttgga
    51301 aacaacgtcc ccacgattac tggcaaagct agcagtacat aagcgattcc acgttgataa
    51361 ggttttgaca acccatggtc atgatcgtgc tcgtgtgcct tttcttctgc ttttccgttt
    51421 ttgacccaca aatacagctg aactaaagcc aaaagagcag ataaaatcat tgaaagaata
    51481 gctaagtagc gataatggac attgatatat tgatcgagtt tgccagaaac ttgcaagtac
    51541 atcatcaatt cgaaataccc agataaaatc aaaaaccgca gcatattttc cctcctaaat
    51601 aaataatgtg aatccaataa cgctaagggc aatcagtccg atcagcgata aaataaagcg
    51661 tcctgtaaaa tatcgtttca tcatcagtag atttttgata tcgaccattg ggccaaagac
    51721 caaaaaggca gctacaggtg ctgtgccgaa cagacttaac aaagaagatc ctataaacgc
    51781 atctgcttct gagcaaagag acatcgtaaa ggccaataac agcatgatga taatggctaa
    51841 aatctttgtt gagccgagcg ttagcataat tctagttggt aaataagtct gcatcgcagc
    51901 tgcgattaat ccgccaatga tcaaataacg acctgtatca aaaaattcgt cgattgaatg
    51961 tgtcaacaca tgcccagttt gatggatcag ctgatttttt ggttcattct tctcactttg
    52021 ttcttcttca tggacatgat gatggtgatt ttctgctact ttagacgtga ttttttcttt
    52081 caatacagcg tctttttgaa aataggcaag ccagacacca atcacaaggg caacaaaaaa
    52141 gctgcctatc acccgccagc ttgccatctg ccaagaattg ccaaatgcga taaaagtgga
    52201 aaaaatcacg attggattga tgatcggagc agtcagcata aaagcaaacg ctgtgtgaac
    52261 tggtacgcct tttttaacaa attgatgaac gatcggtacg atgccgcatt cacatgaagg
    52321 aaagaaaaat cctaagatcg aaccagtaaa aatagagaag atacgatttt caggaagcca
    52381 tctcttcaca cgttctgggg tcaaaaatac ttgtaaggcg cctgagataa gacagcctaa
    52441 taatacgaaa ggtaatgctt caataacgat cgataagaaa atcgtactca tctgcaaaac
    52501 cgaatttgga ataaaagaaa acatgagttt cctccttttt atttctagtt cattcgcttt
    52561 gcaaatatac gcttttattc aaaaaaaaca agttgctctg taaattttta cacaactctt
    52621 attttttacc aaagcacttc aattgacttt ttctgttatt cccattaaat taaggtctca
    52681 tacatatcac ttctatcata aaagggagaa taaaaatgaa acaaaccact aacttgactg
    52741 aagttcaaga catactgcaa cagtcatccg ttgccgtcat ttatctttcg atgcctaatt
    52801 gcagtgtttg tcacgctgtt cgtccacgac tagaggaact tctcacacat tatgatattc
    52861 cggcacttca tttggatgca tttgaaacac cagaagtagc tagtaaattt gaagtgctga
    52921 ctgcgccagt tgtcctgatt tttcatcaag gaaaagaagt ctttcggcaa gcacggttca
    52981 tcgactttaa aaaaatccgt tatctactag atgaactgac agcagaagat gattcccttt
    53041 cttatgaaga aatcttccga acaaaataat cgttgtccaa acagaaaaaa gcgattgaac
    53101 aagtgaaagt tttgccttca tttgttcaat cgctttttat ttttattctg ctgtattttc
    53161 ggaatgcgca tttgcgtcag aatgcaagaa atagatcaag gtttgcaatt cattcgtcaa
    53221 atcaacattt tggatcaata catctgacgg agcattcaat cgagcagcgg taaagttcaa
    53281 gattcctttg attcctgctt ccgttaactg attgactact tcttgtgctc tttcagcggg
    53341 tatcgttaaa attgctactt cgatttgttg gatcttgatt tgttctgaca tatcttccat
    53401 tggataaacg gggataccgt ctacgatgcg cccaacgatt tcctcattca catcaaaagc
    53461 acaactgata cgtatgctat tactttgatg gaatttgtat tttagtaaag cacttcccaa
    53521 gttccctaca ccgatcagcg caacatttgt caattgatcg tcgtttaatg tctttgcaaa
    53581 aaagtgcata agatcttcta catcataacc atacccacgt tttcctaatt cgccaaaata
    53641 agaaaaatct cgacggatcg ttgcactatc tacttgaacg gcttcactta attcagttga
    53701 agacactttt ttctttccag cattatttaa aatccttaaa tagcgataat acaaaggcag
    53761 tcttttagct gtcgcctttg gaataatatg atctttcacg aaatgacctc cacgtattgt
    53821 ctaattacat ctttgatttc tccatcatag cagtatttat aggaaaaaat caattccatt
    53881 gctcagatat tgtgaaattt tattctttat tcatttattt atcatttctg caaatctcgc
    53941 agtataatgg aatttatggt agactactaa ttgaaaaata gttttttatt tgaggagaat
    54001 tcacaaagta gaaaagagga ttccatgata ttattacaag ccaatcagat tgctcgccat
    54061 tttggtgcag aagtcttatt tgaaaacata catttagaaa tcagtacagg cgctcgtgtc
    54121 gctttagttg gcagaaatgg cgctggaaaa tcgactttat taaagatcat tgctggaatt
    54181 gaagcacctg atgaaggaaa gatcgctaaa aataaaacag cgactctcgg atacctcgct
    54241 caggacacag gacttgattc caatgaaaca gtttggaacg agatgctgaa agcttttgaa
    54301 caagttagac aaatggaaga gcggatgcgc gagctagaga ttttcattag cgaaggtacg
    54361 ccagacacac ctgcttatag ttcttattta aaagaatacg accggctgca acacgatttt
    54421 tcagatcgaa acggctatgg ttatgaaaat gaaattcgtt ccgtattgca tgggtttaaa
    54481 ttcgattctt cattttatga tcagaaaatc gatactttat caggcggaca gcgcacacgt
    54541 ttagctttag ctcgcatgct tttgcaacac cctgacattt tgattctaga tgaaccaacg
    54601 aaccatttag atatcgagac actttcctgg cttgagaatt atctgcaaag ctatactggt
    54661 gcattattga ttgtttccca tgaccgttat tttttagata aagtagtcaa tgaagtctat
    54721 gaattaagca gaagaaaaat gcgccattac aaaggtaact attcgaaata tctagatttg
    54781 aaagcagaac agttagcaag tgaatggaag gcttatgaaa agcagcaaac agaaatccat
    54841 aaattagaag acttcgttgc tcggaacctt gttcgcgcct ctaccacaaa acgagcgcaa
    54901 agccgcagaa agacattaga aaaaatggac cggctggatc gtcctcaagg ggatgaaaaa
    54961 caagcaaact ttctattcag tatagaaaag ccttctggaa atgtagtctt gcaaatcgaa
    55021 gatgccgcta tcggatatga taatgtcacc ttatctgaac caatcaatct agatatccgt
    55081 cgtcaagaag cgattgctct agtaggtccg aatggtatcg ggaaatcgac gttgctgaaa
    55141 tcaatcattc accagatccc ttttatccgt ggaaaagaaa cgctagggac aaatgtcacc
    55201 atcggctatt acgatcaagg tcaagctgat ctgcatacaa acaagacgat cctagcagaa
    55261 ttgtgggatg agcatcctac cactccagaa aaagagatcc gaagtgcttt aggtgctttc
    55321 ttattttctg gcgaagatgt agaaaaacca atccctctgc taagtggcgg tgaaaaagca
    55381 cgggttgctt tagccaagtt agcgatgaac aaagaaaatt ttttgatttt ggatgaacca
    55441 acaaaccatt tagatattga caacaaagaa gtattagaaa atgcattgat cgattatgac
    55501 ggcacactgc tttttgtttc ccatgaccga tatttcatca atcggatcgc gacaaaagtc
    55561 gtcgaactct ctgaaaatgg cagcaaagtc tatctaggag actatgatta ttatttagag
    55621 aaaaagcagg aagaagaaga aatcgccgaa ttgttggcac aagatgagcc agaatctgct
    55681 cctgctccca cgaacaaatc tgattattac caaagcaaag aacagcaaaa gcttatccgt
    55741 agccttcaac gaaaaattac tcaggttgaa gaagaaatgg cgcggatcga tgaatggatc
    55801 gatcagttgg aacaagaaat ggtcgcgcca gaaaacctgg aagatcacgt aaaactcaat
    55861 gagctgaacc aagatttaga agctgctaga caagatcaag aaacaaaatt gacggaatgg
    55921 gaagaactaa gcttggaatt agaagaatat gaaaattaac gaaaaaacca aaacagaaac
    55981 cattcatgct gttttggttt ttcttttttt attttatcaa acaaaaattc catatttacc
    56041 tttttcacca ataagaagac caattactag tcattctcac taaagcttct aaataatagt
    56101 aatcacccca aatacaaggt gtatttaccc cattattttt gggcttatta taaacagact
    56161 gtgttaaaaa gccatcttct tcttccgttg tagcatatct ttctttcaat tgtcgcataa
    56221 ttttccaaac agcagactgg tataagttct tttctgtttt gtctaataga cctgattcta
    56281 ttaattctaa taatccacaa accatgatca ccatactaga tgtatctttt tcttctctgc
    56341 tagaatcatc aaagatcaaa tcccaataac aaatggtatc ttctggcaac cgattcataa
    56401 aataattggc taatattttg cttaaatcaa aatatttttg ttctttcaaa taacgataac
    56461 ttaatgcaaa accgtaaatc ccccatgctt ggcctctagc ccaacaggaa ttatcactat
    56521 aaccttgatg cgtacttcca tatcttggtt ttccatcttt gacatccata taaaatgtat
    56581 gataagttga accatcttct cttactaaat aatctgctgc attttgaata tgagcctgag
    56641 cagctttttt atatttttga tttccagttt cttcactcgc ccaatacaat aatggaagat
    56701 tcatgcaaca atccatgatc attctacctt gttgtgaagg atcactagga tctccccaag
    56761 cttgtataac tcctgccttc tcccaaaaac gctgaagtaa tgtttctgca gcatcaattg
    56821 aagcttcctt catttttcga tttcccgtta ttttataatc tgctacggtt gataaagaat
    56881 acaaaaaacc aagatcgtga tgattagtga taatttgaca gtcaatcctg tggataaaat
    56941 ctatatctgc tttttcagct gtttgttgaa ataaaggatc acccgtcttc tcaaataaca
    57001 accaattaat tcctgtccaa aatccttctg tccaaccaat attgtctctt aatggataac
    57061 gtccttttat aggacactcg cttgggaatt gatactgact gttactgata cgtttgatta
    57121 acctctccgt gtgtctgcga caacgctcga tctcattatt ccattctttt tccattaatt
    57181 ctttataaca ttcatttatc catttttctg gatgtattat ctcttcaaac atcactttat
    57241 caagcatttc cccaccagcc tttagcataa ttttagtctt tttttattgt ttttattttg
    57301 gatagttagc ccggttgtcc catcaaaatc aattttggga cgattgttcc atacttctaa
    57361 actataatcc cgatcttgat gagcaaccac tcctgttccg agccaatggg ttccttttcc
    57421 aaatgtaccc tctaatccag gaataaaagt gttttcccat gtcatcaagt ttgtattggg
    57481 caaacccata atagctgtgg attttcgttt aatagtatcg tcacttaaac agataatacc
    57541 tgaaaagcca gcttcactca ccctatagtt ttccttgtct tcttctatga ttattccttc
    57601 tttctcagga gaacattcaa tagcaaaccc tgtctcatat agaacatatt ctgtatctaa
    57661 ttctactttg tgtacgcgaa tctgccagcc ttcaaaagga ataagccaag ttctgatttt
    57721 tgcctgtaaa gtaggttccc atgtagaggc aagtacctct ttcttacata caatgtctcg
    57781 tacattattt cgaacgatga actgtccata ggttttgatg ctctcattct taaaactggt
    57841 cgtgatatat gtgtccgctc gctgaatccc tagcattgaa tccattgcca tttctgcttt
    57901 caattgattc gctcgcggta tcgaaaaacc aaattgacta gaataagcaa attttaaata
    57961 tttttcattg gtcaatgtat ggaaatttgg ccctaattgt cccgcattca aaaaaaatgt
    58021 atgtccatta tcatgttgta tgagcaaatt ggcttctgaa agaagtttag ttccttcacg
    58081 aataggcata ggcatttctt tagccgtcca atactcatgg tcttcaggta gcgccaacaa
    58141 taaaaaaatc ttattcagcc ataatggaga taacgtacta ttatagggtt cagtcaatgt
    58201 caattgaggg taggtataac caatattcag gatacctttt tcatcaaata tttctttttg
    58261 catccaccat cttatattcc gattgactaa ccccttgatt tcacctaatt taaaaggcaa
    58321 aagatcggcc cacaacatag ctgaccaaaa gcttgaaact gcaaaacgat aaatcatgct
    58381 tcgaccaaaa ggcacatttg caccatcttc cgcaaaaaaa tgaatatagt ctctagaaaa
    58441 atcaatagct cggttcttat atatctggct aatgggcttt tctggttcta gtacgctata
    58501 aatcaaacca taataatgaa atgcaaaagg attataataa tcttggcgac ctcttgaact
    58561 gtctcgatac cagccatttt gaagataaca attttctata ttatcaaatg cttctttcag
    58621 tgctgattct ttaactggat aaccaaattt ttggataatt gttccgacaa ttatcttaaa
    58681 aaattgccaa ttaccatctg cacattcata ttcaaaaatt tgcgagaacc aatgaataat
    58741 ctggcttttt tctcctgtat ctaatttttt ccataataat tgttcatgat gatataacgc
    58801 taataacatt gcgggcattt ctaccatacg ctggtctctt tcatgtattt ctccccaata
    58861 atcgggatgg gaaggatctg ttccagcttt tattcctgat agaattaatt tcaaccatcg
    58921 ttcatctaat tggtcaattg cgggccccgc tccccataaa acccgagaga atccttccat
    58981 tcctgcaatt ttatttccat atcctacccc ttgatgtata taatcaattt gtgcgccact
    59041 tgctcgataa aacggctgga gtggttgatt tatcttttta aataagtcaa agtaatcctg
    59101 tctggtcctt aatagtggta ctggatgttt cattgtattt tctcctcttt ttactaccaa
    59161 atagctaatt ccgactgttc taatcgaagt aagccttcaa taaaaaaata atcagaatag
    59221 atcagtggca cattataagt cagttctcta tggtatgctt ctgctccgcc tccaatgatc
    59281 ccatcttcat ccatattcca atttgcatag tgcttttctg tcttttggag tatattgata
    59341 gcagcttcat gatacatttt tgatcgtaca gaggaaacat atcctgctaa ttccagaaga
    59401 ccgcatgcag cgcatactcc agcactggta tcaatattcg aatcttttac agcaaaatca
    59461 atgagaggaa tataaccagt tttttcgatt ttctgaataa aatttactgc tatcttttct
    59521 gctatagcta gatagtacgg attttttgtg taacgataac ttaacgcgaa tccatataaa
    59581 gcccatgcat ttcctctgct ccaacaagaa ttctcattgt atccttgccc gccaagtaac
    59641 cgaatatatt tccctgattc tgcatcaaat tctgcgatat gcccggttga tccatctttc
    59701 ctcactagat acttagctgt tgtatctgca tgctgccgag caattttaga gaacctcgga
    59761 tcaccagttt ccctcgaagc ccaatacagt aatggtaaat tcatcatact atcaataatc
    59821 atccaaccag gtttatggtc attccatgct actaaatagt tccctgaaat attatagcgt
    59881 ccagcaagta ccgtagctgc atgtaaccct agttgtcgac tatgtttgtt ttgagactgt
    59941 tgataatgtg caatagccga tggtaagaat aaaaaaccta catcatgatg aacgtctgaa
    60001 aaatggtaca gggcagattc taataattgt tcttgttgta ttgctgcctc tttgaacttt
    60061 tctcgttttg tcttgtgaaa gagctgccat aaaataccac tccaaaaacc attggtccac
    60121 cagtcgattc ctctgtcctt tattacgtct gtatattttc cgttgtaaga aatatatgga
    60181 attttattcc ccattctgtc taattccgca tctatctttt cagaagctac attcaaaatt
    60241 tttcttgacc attccttcgt ctgttcattc atggatatcc cgccattctt ttaattttta
    60301 tgaatgtgga gttgctccta gaacgaacta gatggttaac attcgttatt ttttttactt
    60361 atttgcagct ccaatgtcat tctccttaaa tttagactgc gcccacacat aaatcaagac
    60421 cattgggatc actgaagttg ctaaaattag cataattgcg ccataattaa ttggctcacc
    60481 tgtactagaa accgtcatat ttttgataat taagggaacc gtatatttat ctttatctga
    60541 aagcatgact aatggaaata gatattgatt ccaacttccc ataaagataa gtaaaccact
    60601 agtaataatc gtaggtgata aaatcggtac agcgattttc gtaaaaatca cccactcatt
    60661 ggcaccatcg attctggcag cctccatcag tgctgtagga aattgactgc tatattgtcg
    60721 catcataaac actgaagttg tactggcaat cgaagggatg atcacacctg cataagtatt
    60781 cgataatcct aaacgactca taatgtaaaa taaaggaatc aatgtggtaa aaaaaggcac
    60841 catcctagat agcataactg tattgaacaa cagtttattc cccataaaac gatactttgc
    60901 taatgcataa cccgccattg tagaactggc tgtagctaaa actgtactga ttacagcaat
    60961 aacaatcgaa ttccaaataa tcaagggata attatatctc gccatgatgg cttgccagtt
    61021 ttttaatagc atatccccaa acttgaaatt gattccgcca cttaaaattt cttgattact
    61081 ttgcgttgaa gctacaatca tatataaata tggcatcaaa aatattaagg caccaaacac
    61141 aataatgacg tacgtaaaaa ttctgctttg tatcttttgt ttagtcattt ttatcacctc
    61201 cgaatttaaa ttgaatagcc gataatataa cagatacaaa caccatcgtc caggcaatag
    61261 cagaggcttt tccaaaatca accatttcaa aacttgtttt atataaattg actcctacga
    61321 ccaaagctga attttctggt ccattggaag tcccaaagaa tatatttggg atattgaaat
    61381 tacccaagcc attgatagtg gctaaaactg tggccattaa aatgattggc tttagcatgg
    61441 ggatcgttaa taaaaagaat tgccgaaatt tcgatgctcc atctatttca gcactttcgt
    61501 atatctcttt agaaatccct tgaagaccag ctaaaaataa aatagtgtta tatcctacac
    61561 taagccaaat catcgtgatg atcattgata ttcgtatcca aaaaggattt gttaaccact
    61621 gtacaccgtt aattcctagc gcattcaaaa atccattgaa taacccagtc ggattgaaaa
    61681 aagtcatgaa tacggaagct acagccaccg ttgatgtaat ggttggaata taatagacag
    61741 ttctaaaaaa tccttttcct tttaactgtg ctgaattcaa taaaacagca aagtaaatag
    61801 ctaatagcat cgttattgga attgatcctg ccatgataat caaaacattc gtgtaagatt
    61861 taataaacaa tggatctcgg aagatagcta gataattgtc aaatccaaca aattcaaatg
    61921 agtagccaat tttcataaaa ctaaaagcaa acgagataat gatgggaatc aaaatcgtca
    61981 caataaagaa aataacaaaa ggtgtgacca atccataagc acttttttta tgagacgtat
    62041 ctgttgcttt tttcttgctg ttctttattg tcttgcttgg taacgaagat tgcatcatcg
    62101 ttaagtcctc ctaatatttt ttaatcacca gttaatttta cgccgtactt atgagcaaaa
    62161 ttttctgctt cttttagata tgaattttca aaatcacctg tttgccaata gttatatgca
    62221 gcggtagtca aataagacgt agcatctgaa taagtggctg gtaaaacagt atttgatgta
    62281 ttttcattga ttttattcaa tagttcatag tatttttgtc ctccttagta gtcaaacttt
    62341 ttctcagctg cttctgtttg ataggccaat gagttagatg tagccacgcc cagctccagt
    62401 gcgttggcta agcattcttc atctgtcagc ataaatgtaa gaaattgttg tgccacttgt
    62461 ggattttttg catctttagg gacataaaaa cttgatcctc ctgatactgc accttttcct
    62521 ggattttctt ttgaaaaagg aatcagtgga gccatgcgcc atttgtcaga tgcatcagga
    62581 aaattcaaag acatattcgt agcataccag ccgccagcaa caaacattgc agattcttga
    62641 aatgctttct cagcatcttg tgcaccgtag aaatgtacaa tatctgagtc gatcatttct
    62701 ttgattaact ttgcagcatg tttcgcttct ttagtattca gacggatatt tccttcttca
    62761 tcaagcaaag attgattctg ctgggctagc atgttgataa acaattcttg gtccccagat
    62821 tctggcaagg caattccaaa actaccagtt ttttctttta atgcttttgc cacctggata
    62881 tattcttccc aagaactgat ttcttcaaaa tctacaccta tttcagcaaa tttttttggt
    62941 tgataataac aaagtgctgg ggtaaaatca ctagcccaag gaataatcgt ttcattactc
    63001 gtttgttgac gcaaaatatt caatttttga tcataaaact gatcgccata tttgtcataa
    63061 aatccatatt catcagcact ataaaaagca tcttgaaatt tttccagcac acctgctgct
    63121 gaagtgtctg ccatggagat aatatccggc atatcttcgt gtgttaccaa ttttggggtg
    63181 atcatttgta ctgttgctgt tcccgaagct acattcacaa tttttaagtc aatatttgct
    63241 ccagttttgc ggttatagat ttttgcagca ttttcaacat agtttgtcag tttgccgttt
    63301 gcgacatata cttctaatgt agtggctttt tttatcattg gatctgcgat gtttgctgtt
    63361 acttcttcgt tagtttttcc acatgcactt aagctgaata atagggtaat gtttagcaaa
    63421 gctatcacca atttgtatct ttttttcatg tctatccctt ctttcttttc aagttcttat
    63481 ataaaacgct ttcacttatg tatattaacg gaattagtaa cacaaatatt tatataaaaa
    63541 aatattttac ttgtcgtttt ggcttttcat ttttgttata atagtcatta attataaata
    63601 gaaagctttt tatataaaaa gagaaaggaa agtggttctt ttgttaacaa acaaccaatc
    63661 ctccaatctt gtcaaaaaaa cactaaccta ttccatagat acccatcttc atttatctgc
    63721 tgctccctat tttcgactac taataaatga aagcgctaat ttatatgctg aatttgcaca
    63781 taaatctata gaactagata atccttccct tttattcatt gataaacagc aagaagtcca
    63841 aatcttttct actcaaaagg aaacacaaac ttttatcatt atccagtttt attttgatga
    63901 gcaattatta gcacatatta cgggacaatc tttttctata gatcaagaaa taacatctat
    63961 cattactttt ctgaaaaatg aacagttcaa aattgattat ctaaaacata gtaagccagc
    64021 tatttcctat gatcaggaaa tcaattcttt tttcatacta tgccaacaga tgagcattca
    64081 tttgctttcc ttattagtta cttattgtct gcaaaaaatt caattgtctt ccttaccaag
    64141 gcattatcaa caggaacttg ctttattgac aataccttca aatgagaaag tcattcctaa
    64201 aaaaaagcat attctttatt cagatgaatt agttgatcca atcatacgat atttagaaga
    64261 acatctttca gaaaattttt tgcttgaaca attagcccaa atttttttta tcagtccagc
    64321 cagcttaaaa aaacatttta gaaaagtgaa tggaaaaagt gttattagct attttaaaga
    64381 actaaaaatg gaaaaagcaa aacgtctcgt gctagaaaat gaattaacct atacagaaat
    64441 tgcagatata ttaggatttc attcgatcca tcatttttct tcagctttta aaaaatatac
    64501 agggttatcc ccttcaaagt attatctatc cttaaaatag aaaaaaattt ttaggtttta
    64561 tccacaaatt atttctctat attttctgtc tattcaaaat aaacaataat tttccggcac
    64621 aattatttgc tgttttttac cataacatag tacgatcaac gtagaaaagg agatgttttt
    64681 atgaaagttg ttgtcattgg cggtgtagct ggcggtcctt catttgccac tcgtttccgt
    64741 cgattgaatg aagcgcacga aatcattatc tatgaacgcg gagaaaatat ttcttatgca
    64801 agttgtgctt tgccttatta tttaggaggt gtgatcactg accgtgactc gctgatcgaa
    64861 cgtacaccag aaatattgaa aacaaaaaac aacatcgatg tctttactaa acacgaagta
    64921 acagcaatcg atccttctac taagcgatta acagttaaag acctatccac aaatgaagaa
    64981 ataaaaacag attacgataa gttgatcatc tcttctggtg ctagaccaga ttatccggat
    65041 attcccggag tttttgaagc agaaaacggc tttgtcctcc gtagtgtgac ggatgcggat
    65101 cgaatcaaat cgttccttga agaaaaaaat ccacaacatg tcgtcattct tggtgcaggt
    65161 gttatgggtc tggaattagc tgagaatttc aagcatcgcg gcttagacgt gactttaatc
    65221 gatcaattgc cacaagtcgc tttcccttat gatccagaaa ttgctaattt agtttatgac
    65281 aaattgctga aagaaggatt agccgttcat ttagaaacaa gagttactga gatccgtgat
    65341 aaaggtcgag aaatagtatt atcagatggc tccgtccttt ctgctgatat gctaattttt
    65401 gctgttggtg tttctccgaa gaatgaagtg gtgaaagcaa ccggcataca attatcagat
    65461 acaggtcaga tcattgttga tgaccagtta caaaccaatc tgccggacat ctatgcgatt
    65521 ggcgatatta tcgaaacgac tagtgtagtg actggtcagc cgatccaaag tatgctttcc
    65581 agtgcggcca atcgtcaagg acatatgctg gcagatattt taaatggtac gcctatgcgc
    65641 tatcgcggat atattggtgc aggtgtcgca aaaatctttg atcatacagc aagttatgcg
    65701 ggaatgacag aacatgaatt aaaagcatca ggcataacaa attataaaac tgtttttatc
    65761 actccctttg accatgccta tttctatcca gaagctacaa gattaaatct aaagctgatt
    65821 tttgatgcag atagcggtcg tattttaggt ggacaagcat ttggagaaaa aggtgtcgat
    65881 aaacggatgg gagaactttc tgtagcaatc accggaaact tgacagtctt tgatttgcct
    65941 gatttggagt tgccttactc tccaccgtat tctactaccc gtgacccgtt gaatatagct
    66001 ggttatgtcg caatcaatca aatgacgaat atcgtagaaa cgatcaaagc aagtgatata
    66061 cccgaaaacg atttgaaaga agcgttcttt ttagatatac gtgaacctaa taaagcacct
    66121 tctggcagta tctcggcaac aaaaaatatt ccaatgaatg agttacgaga tcgaatcaat
    66181 gaaatcccaa aagataaaaa agtttacatt actttcagaa gaggattgaa tacttatact
    66241 tctgcccgaa tcttggcagg tttgggtatc aaagcgattt tgattgaaga ataaaaaaac
    66301 gaccgcggtg ggtagccgcg gtctaggagt tatttttact tgaggagtaa aaatgaaaaa
    66361 gtatataggg ttgttggttg gtatgtatat agaatagaag ataaatgtga agaaattgtg
    66421 cattatttct tcacatttat taggttatag tttaagaaag tttaaacatt gcgcaattta
    66481 attattttag ctgtttcttt tcataaaaaa acatgttgtg actctgagac aaatcatagt
    66541 ccatagtgat gtctctagag taactacgcc taatattacg aggcatcata ttaatctatc
    66601 agcactagta cctaaactag catccctttc gaatattttt tcttatataa taaagtttgc
    66661 tttcactcct ctaatctcac caaatcgact ggcttgcgtt gtgtgatact aggaactgat
    66721 tggtttagaa cgacttttct attgtaatca tatttttcgc catcctcgtt gtcttctaat
    66781 ccttcaatga atgatcccta atgtgtgtat taaataattt aatttttttg ttcctattta
    66841 tttaac
//
LOCUS       DACCVH010000005        66205 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.005, whole genome shotgun sequence.
ACCESSION   DACCVH010000005 DACCVH010000000
VERSION     DACCVH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.005"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            4..861
                     /locus_tag="IVV98_000383"
     CDS             4..861
                     /locus_tag="IVV98_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP7806068.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            976..1896
                     /gene="pstC"
                     /locus_tag="IVV98_000384"
     CDS             976..1896
                     /gene="pstC"
                     /locus_tag="IVV98_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP7806069.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1896..2780
                     /gene="pstA"
                     /locus_tag="IVV98_000385"
     CDS             1896..2780
                     /gene="pstA"
                     /locus_tag="IVV98_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP7806070.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2795..3601
                     /gene="pstB"
                     /locus_tag="IVV98_000386"
     CDS             2795..3601
                     /gene="pstB"
                     /locus_tag="IVV98_000386"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP7806071.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3617..4375
                     /locus_tag="IVV98_000387"
     CDS             3617..4375
                     /locus_tag="IVV98_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP7806072.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4388..5065
                     /gene="phoU"
                     /locus_tag="IVV98_000388"
     CDS             4388..5065
                     /gene="phoU"
                     /locus_tag="IVV98_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP7806073.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5303..5602
                     /locus_tag="IVV98_000389"
     CDS             5303..5602
                     /locus_tag="IVV98_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806074.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5628..6335
                     /locus_tag="IVV98_000390"
     CDS             5628..6335
                     /locus_tag="IVV98_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP7806075.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6332..7099
                     /locus_tag="IVV98_000391"
     CDS             6332..7099
                     /locus_tag="IVV98_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP7806076.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7199..8767
                     /gene="liaX"
                     /locus_tag="IVV98_000392"
     CDS             7199..8767
                     /gene="liaX"
                     /locus_tag="IVV98_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP7806077.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9067..9384
                     /locus_tag="IVV98_000393"
     CDS             9067..9384
                     /locus_tag="IVV98_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP7806078.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9384..9734
                     /locus_tag="IVV98_000394"
     CDS             9384..9734
                     /locus_tag="IVV98_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP7806079.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            9901..10839
                     /locus_tag="IVV98_000395"
     CDS             9901..10839
                     /locus_tag="IVV98_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP7806080.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10854..11684
                     /locus_tag="IVV98_000396"
     CDS             10854..11684
                     /locus_tag="IVV98_000396"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP7806081.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11728..12753
                     /locus_tag="IVV98_000397"
     CDS             11728..12753
                     /locus_tag="IVV98_000397"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP7806082.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12768..13706
                     /gene="galU"
                     /locus_tag="IVV98_000398"
     CDS             12768..13706
                     /gene="galU"
                     /locus_tag="IVV98_000398"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP7806083.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13831..14271
                     /locus_tag="IVV98_000399"
     CDS             13831..14271
                     /locus_tag="IVV98_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP7806084.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14274..14876
                     /locus_tag="IVV98_000400"
     CDS             14274..14876
                     /locus_tag="IVV98_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP7806085.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(14944..16050)
                     /locus_tag="IVV98_000401"
     CDS             complement(14944..16050)
                     /locus_tag="IVV98_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP7806086.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16260..17261
                     /gene="ccpA"
                     /locus_tag="IVV98_000402"
     CDS             16260..17261
                     /gene="ccpA"
                     /locus_tag="IVV98_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP7806087.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17564..19909)
                     /locus_tag="IVV98_000403"
     CDS             complement(17564..19909)
                     /locus_tag="IVV98_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP7806088.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20188..21090
                     /locus_tag="IVV98_000404"
     CDS             20188..21090
                     /locus_tag="IVV98_000404"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP7806089.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21303..23078
                     /locus_tag="IVV98_000405"
     CDS             21303..23078
                     /locus_tag="IVV98_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP7806090.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23335..24552
                     /locus_tag="IVV98_000406"
     CDS             23335..24552
                     /locus_tag="IVV98_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7806091.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(24999..26585)
                     /locus_tag="IVV98_000407"
     CDS             complement(24999..26585)
                     /locus_tag="IVV98_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP7806092.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26836..27060
                     /locus_tag="IVV98_000408"
     CDS             26836..27060
                     /locus_tag="IVV98_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP7806093.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27202..28953
                     /locus_tag="IVV98_000409"
     CDS             27202..28953
                     /locus_tag="IVV98_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806094.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            28953..30737
                     /locus_tag="IVV98_000410"
     CDS             28953..30737
                     /locus_tag="IVV98_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806095.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31195..32046
                     /locus_tag="IVV98_000411"
     CDS             31195..32046
                     /locus_tag="IVV98_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7806096.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32143..34029
                     /locus_tag="IVV98_000412"
     CDS             32143..34029
                     /locus_tag="IVV98_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7806097.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34070..34972)
                     /locus_tag="IVV98_000413"
     CDS             complement(34070..34972)
                     /locus_tag="IVV98_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7806098.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35202..36605
                     /locus_tag="IVV98_000414"
     CDS             35202..36605
                     /locus_tag="IVV98_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7806099.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36605..38038
                     /gene="ascB"
                     /locus_tag="IVV98_000415"
     CDS             36605..38038
                     /gene="ascB"
                     /locus_tag="IVV98_000415"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7806100.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38183..39109
                     /gene="trxB"
                     /locus_tag="IVV98_000416"
     CDS             38183..39109
                     /gene="trxB"
                     /locus_tag="IVV98_000416"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP7806101.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39322..41049
                     /locus_tag="IVV98_000417"
     CDS             39322..41049
                     /locus_tag="IVV98_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP7806102.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41122..41415
                     /locus_tag="IVV98_000418"
     CDS             41122..41415
                     /locus_tag="IVV98_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP7806103.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(41499..42359)
                     /locus_tag="IVV98_000419"
     CDS             complement(41499..42359)
                     /locus_tag="IVV98_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP7806104.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42451..42879
                     /locus_tag="IVV98_000420"
     CDS             42451..42879
                     /locus_tag="IVV98_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7806105.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43041..43217
                     /locus_tag="IVV98_000421"
     CDS             43041..43217
                     /locus_tag="IVV98_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP7806106.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43244..43690
                     /locus_tag="IVV98_000422"
     CDS             43244..43690
                     /locus_tag="IVV98_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP7806107.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43846..45225)
                     /gene="brnQ"
                     /locus_tag="IVV98_000423"
     CDS             complement(43846..45225)
                     /gene="brnQ"
                     /locus_tag="IVV98_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP7806108.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            45931..46902
                     /locus_tag="IVV98_000424"
     CDS             45931..46902
                     /locus_tag="IVV98_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP7806109.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            46926..49118
                     /locus_tag="IVV98_000425"
     CDS             46926..49118
                     /locus_tag="IVV98_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP7806110.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49135..49611
                     /gene="ybeY"
                     /locus_tag="IVV98_000426"
     CDS             49135..49611
                     /gene="ybeY"
                     /locus_tag="IVV98_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP7806111.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49589..49990
                     /locus_tag="IVV98_000427"
     CDS             49589..49990
                     /locus_tag="IVV98_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP7806112.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50005..50904
                     /locus_tag="IVV98_000428"
     CDS             50005..50904
                     /locus_tag="IVV98_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP7806113.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51047..51859
                     /gene="recO"
                     /locus_tag="IVV98_000429"
     CDS             51047..51859
                     /gene="recO"
                     /locus_tag="IVV98_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP7806114.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52243..53160
                     /gene="glyQ"
                     /locus_tag="IVV98_000430"
     CDS             52243..53160
                     /gene="glyQ"
                     /locus_tag="IVV98_000430"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP7806115.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53162..55237
                     /locus_tag="IVV98_000431"
     CDS             53162..55237
                     /locus_tag="IVV98_000431"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP7806116.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            55627..56406
                     /locus_tag="IVV98_000432"
     CDS             55627..56406
                     /locus_tag="IVV98_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806117.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            56452..57396
                     /locus_tag="IVV98_000433"
     CDS             56452..57396
                     /locus_tag="IVV98_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7806118.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            57412..58191
                     /locus_tag="IVV98_000434"
     CDS             57412..58191
                     /locus_tag="IVV98_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP7806119.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            58203..58901
                     /locus_tag="IVV98_000435"
     CDS             58203..58901
                     /locus_tag="IVV98_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP7806120.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            58929..59693
                     /locus_tag="IVV98_000436"
     CDS             58929..59693
                     /locus_tag="IVV98_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP7806121.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            59707..61524
                     /locus_tag="IVV98_000437"
     CDS             59707..61524
                     /locus_tag="IVV98_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7806122.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            61578..62501
                     /locus_tag="IVV98_000438"
     CDS             61578..62501
                     /locus_tag="IVV98_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HAP7806123.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYID
                     NPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKK
                     MLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKN
                     LRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            62473..63189
                     /locus_tag="IVV98_000439"
     CDS             62473..63189
                     /locus_tag="IVV98_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP7806124.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            63186..64304
                     /locus_tag="IVV98_000440"
     CDS             63186..64304
                     /locus_tag="IVV98_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAP7806125.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            64297..64914
                     /locus_tag="IVV98_000441"
     CDS             64297..64914
                     /locus_tag="IVV98_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP7806126.1"
                     /translation="MRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLGS
                     PIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELPE
                     LWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKFD
                     LDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            65041..>66205
                     /locus_tag="IVV98_000442"
     CDS             65041..>66205
                     /locus_tag="IVV98_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7806127.1"
                     /translation="MCRVLNILFQYEKIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLF"
BASE COUNT        21896 a        11597 c        13918 g        18794 t
ORIGIN      
        1 ctaatgaaaa aacttaaatt attcttacca ataataggat tagccattct tttatcaggc
       61 tgttcaaagt ggattgatcg aggagaatcc attacggctg ttggctcttc tgctttacag
      121 cctttagtag aaacagttgc tgaaacttac cagacagaaa atcctggaaa attcatcaat
      181 gtacaagggg gcggaagcgg aactggtttg tctcaagtac agtcaggagc agtcgacatc
      241 ggaaactctg atttgtttgc ggaagaaaaa tcggggatcg atgcctcagc attagtcgat
      301 catcgagtag cagttgttgg gatcactcct attgtgaaca aggatattgg cgtaaaagac
      361 atcagtatgg aaaacctgaa aaaactattt acaggcgaga tcaaaaactg gagtgaagtc
      421 ggtggaaaag atcagccagt agttatattg aaccgcgctt caggaagcgg aacccgtagc
      481 acgtttgaaa aatgggtatt ggacggagaa acagctgttc aggcacaaga acaagattca
      541 agcggaatgg tgcgccagat cgttgccgac acacccggtg caatcagcta tgttgctttt
      601 tcttatgttt ccgatgatgt agatacgttg aatgttaacg gtgtagaacc gacagatgaa
      661 aatgtgacaa cgaacaaatg gacgatttgg gcatatgagc atatgtacac aagagatcat
      721 ccaaaaaaac tgacaaaaga atttttagac tatatcttat ctgatgaagt acaagataac
      781 atcgttggag aactaggtta tatccctgtt tctcatatga aagtcgaacg tgattggcaa
      841 ggaaatatcg ttaaagagta atctttacac aaaatttaca aacttagcta aacttttaca
      901 tgttattaaa accaaattga tgttcaattt gtacactgag tgagtatgtt aaacctgatt
      961 aagggggagt catctgtgga agatgtgaaa aaagtattat taacaaaatc aaaacgttca
     1021 aaaatggaac agcgtggaaa attcatcagt tttttatgta tcgcgctgat cgtgttggtt
     1081 gtattatcta ttttttattt tgtagctagt aaaggattgg ccaccttttt tactgataag
     1141 atcaatgtat ttgattttct gtttggtaca gattggaatc caagccaaat cggagcaaat
     1201 gggaaaccaa tggtaggggc attgcctatg atcacaggtt cgtttattgt gaccttttta
     1261 tctgctatcg ttgccacgcc atttgccatt ggtgcagcag tattcatgac ggagatctct
     1321 cctaaaaacg gaacgaagat cttacagccg gtcatcgagc tgcttgtagg tattccttct
     1381 gtcgtttatg gttttatcgg tttatcagtt atcgtgcctt ttgtcagaag tatttttggc
     1441 gggacagggt ttggtatctt agctggtaca tttgtgttgt tcgttatgat cttgccgact
     1501 gtcacaacga tgactgttga tgcattaaag gcagtgccac ggcactatcg ggaagcttca
     1561 ttagcgcttg gtgccacaag atggcaaaca atctacaaag tcgtgctacg agcagccgtg
     1621 cccgggattt taacagcagt cgtttttggt atggctcgtg cgtttggtga agccttagct
     1681 atccaaatgg tcatcggtaa tgcagcattg atgccaacag gacttactac tcctgcttct
     1741 acattgacgt ccatcttaac aatgggaatc ggaaatacaa tcatgggaac agttgaaaat
     1801 aatgtgttat ggtcattagc gctgatcttg ctattgatgt cattattctt taatatcgtg
     1861 atccgtatga ttgggaagaa aggagagctg aaataatgaa cgcaaaacgc tcagataaaa
     1921 ttgctacagg tgttttatat atagtttcgg ggatcatcgt attgatttta gcagctttac
     1981 tactttatat cttagttcgg ggaataccgc atatttcatg gtccttcttg accgaacctt
     2041 ccaaagccta ccaagaaggc ggtggaatcg ggatccagct atttaactcg atttatttgc
     2101 ttttgatcac gatgatcatc agttttccta tttctttagg tgcgggtatc tatctttcag
     2161 aatatgctgg aaaaaactgg ctaacagatg tgattcgcac gtcgattgaa atcttgagct
     2221 cgttgccttc tgtcgttgtc ggtttattcg gtttcttggt tttcgttatt caattccagt
     2281 atggtttctc gattatttct ggtgcattgg ctttgactgt attcaacttg cctcttttga
     2341 ctagaacagt tgaggagtct ttacaagcgg tccattacac acaacgagaa gcaggattgg
     2401 ccttaggttt gtcacgctgg gaaacagtga taaaagtggt ggttccagaa gcgacaccag
     2461 ggattttgac tggtgtgatc ctaagttctg gaagaatttt tggtgaagca gctgcattga
     2521 tctatacggc tggacaaagt gcacctgcgt tagattttac gaactggaat ccattaagtg
     2581 tttcaagccc gatcagcatt ttccgtcaag ctgaaacatt agctgtccat atttggaaga
     2641 tcaatacaga aggcacgatg cctgatggtg tttctgtttc ggctggcgct tctgccgtgt
     2701 tgatcattgc tgttttactg ttcaacttcg gcgctcgtgc gattggcaaa cgattatacc
     2761 gaaaaatgac ttcagcctaa ggagaagaag caaaatgaaa aaatataact ggaatgaaac
     2821 aaatgtcatc accatgccaa aagagaaaga agtagcacta tatacggatg atctacatgt
     2881 ctggtatggc gacaatgaag caatcaaagg agtggatctg gaatttgaaa aaaataagat
     2941 cactgcactg attggtcctt ccggctgcgg aaaatctacg tatcttcgtt cgttgaatcg
     3001 aatgaatgat gggatcgcta atacgaaaat cactgggaaa atcatgtatc aaggcgtaga
     3061 tattaatgcg cctcaagtgg atgtttatga gatgcgcaaa cggattggca tggtttttca
     3121 acgtcctaat ccgttcagca agtcgattta tgacaatatt acatttgctt tgaaacagca
     3181 cggcgaaaaa aacaaaaaga aattagatga aatcgttgaa acaagcttga aacaagctgc
     3241 cttgtgggac caagtaaaag acagcttgga caaaagtgcc ttggctttat ctggcgggca
     3301 acagcaacgt ttatgtattg ctcgtgcgat cgcgatgaaa cctgatatct tgctgctaga
     3361 cgagccggca agtgctttgg accctatttc gacaggaacg gttgaagaaa cacttgtaaa
     3421 cttgaaagaa gactatacga tcatcatcgt gacgcataac atgcaacaag cagctcgtat
     3481 cagcgactat actgcctttt tctatctagg aaaagtaatg gaatatgaca aaactaacaa
     3541 gatatttacc agaccaaaaa ttcaggcaac cgaagattat gtgtccggtc attttggtta
     3601 agacggaggc ctcaacatga caaaagaaat tatttcatct aaagatcttc atctgtatta
     3661 tggaaagaaa gaagcactaa aagggatcaa tctaagtttc aatcaagggg aaatcactgc
     3721 gatgatcggt ccttctggtt gcgggaaatc cacttatctg cgttctttga accggatgaa
     3781 tgacctgatt ccgaatgtaa cgatcaccgg aagtgtttta tataaagaca aagacatcta
     3841 tggtccaaaa acagatgttg ttgaactaag aaaagaaatc ggcatggtat tccagcagcc
     3901 aaacccattt cctttttcta tctatgaaaa tgtcatctat ggattgaaat taaaagggga
     3961 aaaagataaa aaagtccttg atcaagtagt tgaagaaagc ctgaaggcag cgtctgtttg
     4021 ggatgatgtg aaagacaaat tgcataaaag tgctttatct ttatccggtg ggcagcagca
     4081 gcgtgtatgt atcgcacgtg ttttggcagt taatccggaa atcatcttat tggatgaacc
     4141 aacaagtgcg cttgatcctg tttctactgg gaaaatcgaa agtatgctgt tagaattaag
     4201 agagcggtat acgatgatca tcgtgaccca taatatgtct caagcttcac gtatttcaga
     4261 taagacggca ttctttttag atggtcactt gatcgaatac aacgatacga agaagatatt
     4321 catgaatcca gaaaaacaag agacagaaga ttatatttca ggtcgatttg gataaggagg
     4381 aaacggaatg ctacgtacac aatttgaaga agaattgctg aatctccata atcagttcta
     4441 cgaaatgggg atgatggtga gcagcgccgt gcacaagtca gttcgtgcat acatcaaaca
     4501 cgataaaatc ttagcccaag aagttatcga aaacgatata aatatcaata acatggaaac
     4561 acgcttggag aagaaaagtt ttgaaatgat cgcattgcaa cagccagtta caactgattt
     4621 gcgtatgatc attacggtca tgaaagctag ctcggattta gaacgtatgg ccgatcatgc
     4681 ggtgtctgtt gctaaatcca cgattcgcgt aaaagggcag acgagaatac cggaaatcga
     4741 aaaagagatc tccgatatgt ccgattatgt gaaaaaaatg gtggacaacg tcctagttgc
     4801 ttatgtcaaa acagacgaaa aagacgcacg tacgatcgcc aatatggatc aaagagtcaa
     4861 tgactatttc aatcgaatct ataatgcaac aatcaaaaat atgcaggaaa atcctgagac
     4921 agtcatcagt ggaacagact acttgaatgt tgccagttat ctagaacgga tcggagacta
     4981 tgtgacaaac atctgtgaat ggatcgtcta cttggctaca gggaaaatca ctgagttaaa
     5041 tacgaaccac aatgagattt tctaaactga agctgtgatt atgccgtttg tttaggaaaa
     5101 gaggttgtga aatcagcggt tgtgaaaaag ctgttctgca tcaagtaata agaacagtca
     5161 aacaaaaaat agctcctcat atttttcgtt tggctggact tattaccgca gatgcaagct
     5221 tttgaacacc gtttattcgg gaaagggttt gtgacaaaac atgtcacaaa cccttttcat
     5281 catttcatag aaaggataaa gaatgcaaaa aaaaattagc atcatcacta tattttttat
     5341 ttgtgtgctt acttcatggg ttattcagca tcaagctgct ttatatgaag tacctgtcat
     5401 cgagatcgaa aaagtacgaa taaaagagga tcatcaattg attacaggaa gactgatgaa
     5461 cacggatcaa aaaggagaat cgatttattt atcggttcct tatcaaaaaa atcaaataga
     5521 aacagcaaat ataaaagcga gacaaatgta tctagtccaa atgcatggag atgaatggca
     5581 gctagtagca aaaaaaaaat gatggctggc ttttcttctt cacaagtatc tccattggcg
     5641 ccatgttgct tattggcgga aaacagggtc tatttgcttt aggaagtctc atcatcaata
     5701 tcgttttact tttacttttg ttgctcatct ttactaaaac agaagggatt tctctattaa
     5761 atatatctat cctgttcgtc gttataggga tgattattag catattggct ttagatggat
     5821 ggaatagaag cagtataatc aaaatttcag ctgcagttac gagtgttttt ttagcatttt
     5881 ttatttgtct tttgacaatg aatcattgga aagaccaagg actgcgctat gaggaactga
     5941 attatctgac acgaccgtat cgttctgttt ttctttctag cgtactgatt ggaacagctg
     6001 gaggaacact cgataccgtt atcacagtca ttgcgacatt agaagaattg actaagcgac
     6061 aaccagaaat aacagcgaaa cagttatggc tttcaggaag gcaagtgggt cgagatgtga
     6121 ttggctcgat gaccaatatc cttttgttcg tctatatcag tgggtcagtt ccatcgcttc
     6181 ttttatattt aggaaatcaa tggtcgttca aagaaacgat agaacagcat ttatcattgg
     6241 aatttttacg cgtcattgct ggcagcttag gaatagtatt atcgatccct atctcggtcc
     6301 tcttttttct gactgtaagg aggctgaaac gatgaatgta cttattatac ttgttgggat
     6361 tttagcaatc agcgtgctac ttattggcgg tacgcaaggt atgtatattc ttttaggctt
     6421 attcatcaat ttagggatct ttttcctgtt gttattcggt tatcatcaga agtggccgat
     6481 actggcattg tcggtcatag gatttttatt gattgctgtg gttatcttat tttttatcaa
     6541 cggttataat ctaaaaatgc gtgcagcttt tgtgagtata ctgatctttt tattttgttt
     6601 cctactattg cttcctatca ctgatttttt agcgatccaa ggttttacat cggtagaact
     6661 agaagaatta tctggcttag ataagacttt agcgattgat tttagattac ttacgagatc
     6721 gttgcttctg attagtctta gtggtgctgt tttagatgct agtgtagcaa tttctagtgg
     6781 gacattcgaa gtatatcagg caaatccgca attatctttt taccaattgc gccattctag
     6841 tttcgctatt gctaaaaaaa tattggcgtc aacagtaatg acacttcttt ttgcattcat
     6901 gggaagttct ttagcgttga tcctctggtt tattgattta gacattcctt ttcagcaagt
     6961 gatcaatgaa aaatcatttg ttctagaata tacgatggct attcttacca cattgtctgc
     7021 actacttgtt cttcctttaa cctgcgtgac tacagcatat ctctttacaa aaaagaaaga
     7081 acaactcaag atggagtaaa agttacaact taagtcctat gacattttta ctgaatcagt
     7141 gcataatatg gatgtaagga aaagcttgca aacaattttg cttaaggagg caatttccat
     7201 gaaagaaaga gaacgtattt tagatttagt gaaaaaagga atcctttcga ctgaagaagg
     7261 cttagattta ttagaaagca tggcaactga aaaagacgaa aagcaaataa aaaaagaagc
     7321 agacaaggta actgctagtc ataaagaaaa agatcaggca agtcaattga tcgataaact
     7381 tgaaaacggc gaagaagaaa tttctgagcc agttgatcca aaggaaagag aaaggcaaga
     7441 tcaagaaaac ttagaaaaga tcttagatga actagcaact gaagcgaata aaacttcggc
     7501 gcgtctagat gaagtaaatg ctcaattcgc tgacaataag gcagcacgca atgagaaaca
     7561 ggaagcattg atgcagctga atacaaaaga agaattaggc gagttgacag aagaagaatt
     7621 agcacagcgt cagacgttag aagcagaaat caaagaatta gaagctagtg gcgatacact
     7681 gttagaagaa caattgaaat tagaagcaga attaaaagat atccgtaaga atcaatggtc
     7741 tgagaaaaaa gaaacgttta ctgataagtt tgaattgcca gatgattgga aagatcaagc
     7801 aacagataca ctgaatcaag taggcgaaaa aatgtcagaa gctggatcac agttaggcaa
     7861 attcttgaag aaaacattcc aaactgtttc agaaacagtg aatgacaaca tggaatggaa
     7921 agatgtcagc ttacgtgtcc ctgggattgc gacaacgaaa tttgagcatg aattttacta
     7981 tgaagctcct gcagcaagta tccttgatat caaggcagca aacggaaacg tgacgttaaa
     8041 aacgtgggac agcaacgatg tgaaagttga agctaagatc aaactttacg gaaaaatggg
     8101 tgctgaacca tttgaagcat tctctgaacg gagccagatt gaggttaatg aagatcatat
     8161 ctccttccaa attccaaata aacgtgtgcg tgcagacctt gttttctact tacctaaacg
     8221 agtatacgac cacgcagcta ttaaacttct aaatggcaac atcatgattg aaacattgga
     8281 agctaaagat atttatacaa aatctacgaa tggtaacatc atcgtggacc aattaactgc
     8341 aacgatgctg gaagtagaag gtgtaaacgg caatatcgat attcgaaacg ggaacatctt
     8401 agattctatt atcgaaacag taaatggtac agtgacattt ggtgcgacag cagaaaacct
     8461 ttctgtgtct ttggtaaatg gtgatgtacg tcttacgatt aaagaagata atttgaaaaa
     8521 agtagaagca agttcagtga acggaaatgt caaagtcgct ttaccagatg gcatcggttt
     8581 ggaaggacat gctaaaacaa gtcttggaag tatcaacagc cgtctgtcca attacgaagt
     8641 agttcgtgag aaaaaagaac ggacaaacca aatgttgcaa ttccgtcgtg tttcagatgg
     8701 tgaaatcacg caagtgcaac tttcaacgac aacaggaagt atctatttaa aagatacaga
     8761 taaataaaga ggttgtgaaa gagatgttca gccttgagca ataagaagcg attttgtaaa
     8821 atagcttccc ctattttaca aaattgtgcc ttattgccga taggctatct cttgaacacc
     8881 gtttaccaag agattatgaa cctgccaatt atcgccgagt cacaaggaat aatttcagaa
     8941 aaagctcgtc acgttttatg aatatggtaa tttgtgaccg agaattttgc agaaagacac
     9001 cgattaagaa gaaggttgtc acaacgattt tcttcattta aaatagtaga acagaggtga
     9061 gacatgatga aaaaaaagtt gacaaaatcc aataaaaatg ttgttttgac agggacttta
     9121 gcaggaatag gagaatacat cgggattgat ccgactgtta tccgtgtgct ttatgtattc
     9181 ctgagcttag ttgcttttgg aagtccaatc attttataca ttttattagc tttgattatc
     9241 ccatctgcgc gttctgcacg aacaaactat ggacataaca atgcatatta tgaaaaaaac
     9301 aattatcgtg aacaaactcg tgaacaaaca aaaaaacgca aagaagcgga aaaaatcgat
     9361 gatgacgaat ggagtgactt ttaatgtcgt actttcaacg tattttagtt aatacgttaa
     9421 cattcatatc attggctgtt ctttttcctg cgatggtcca tgtgagcagt atttggacgg
     9481 ccgttcttgc cagcttcgta ttgtctgtgt tgaatatgtt tgtcaaaccg attttgacga
     9541 tactgtccct gccctttaca ttagtcacat tgggattgtt tacgtttgtt atcaatgcag
     9601 cgattcttaa aatgacctcc ttttttgtgg gagcagaaca ttttagtttt tcttcattcg
     9661 gtgcagcgtt gttagtagct atcttgatgt cgcttgtcaa tgtaattgtc agtgaacata
     9721 acagtagaaa ataaaagaaa gctgtgccga actatcggcg cagttttttt atttagaatc
     9781 aggaatgcgt tttctattac attggtaatt aaataaaaac gtttttttta attggtagta
     9841 cttttggcta gacaatgata aaatgataga gaacactcta atagaaatga ggtagcatga
     9901 atgtcagaag ttgtaaaagt tagccaatta gtgaaaaaat tatctttgga aatcgtgaca
     9961 ggcgacgaga aaagcttaga ccgtgtcatc gtaactgggg acatctcacg cccaggacta
    10021 gagttgactg gttattttaa ttattattcc cataatcgtt tacagctatt tggcagtaaa
    10081 gaaatcagtt ttgcggaacg gatgatccca gaagagcgtt tgatcatcat gagaagatta
    10141 tgtagtgaag atatgcccgc atttattatt tcaagaggat taccggctcc agaagaaatg
    10201 atccaggcag caaatgaaaa tgggatagct gtactgcgtt ctcccatctc aacttctcgt
    10261 ttattaggag aattatccag ttatttagat ggtcgccttg cccctcgaac aagtgtccac
    10321 ggtgttttag tggatgttta cggattaggt gtactgattc aaggtgacag tgggatagga
    10381 aaaagtgaaa cagcgttgga gttgatcaaa cgcggtcatc gattgatcgc agacgatcga
    10441 gtagatgttt atcagcaaga tgaattaacg gtgatcggag aaccgcctaa aatcctggaa
    10501 catctaattg aaatccgagg aatcgggatc attgatgtaa tgaatctttt tggtgcgagt
    10561 gcggtacgtg gctctatgca agtccagttg gctgtttatc tggaagcatg ggcaaaagat
    10621 aagaaatacg accgtctggg ctctgaagac acgaccgttg aaatcgcgga agtgggcatt
    10681 ccacaaataa aaatccctgt caaaacagga cgaaacgttg caatcatcat tgaagtagcc
    10741 gcgatgaatt tccgtgcacg tacaatgggc tttgacgcaa cgaaaacatt tgaagaaaga
    10801 ttaagtcgct tgattgaaga aaactcaggc aacgactagc aaggagtgac aatatgttag
    10861 cacaaatcaa tcgagttgct tttgagcttg tagggattcc tatctactgg tatgcattga
    10921 tcatcgtatc aggtatcatt atcgccatgt ggcttagcag cagagaggct gttcgggtag
    10981 gattaaaagc agatgatgtg acagatttta tgttgtgggg attgcctatc tccattattg
    11041 gtgctcgctt atattatgtt ttatttgatc ttccccagta tatagctgat ccaatccaaa
    11101 tattcaatat ccgttcagga ggcttagcta tttatggcgg actgattgca ggcgcgatca
    11161 cgctgtattt ttttactaaa tatcatttta tttctttgtg gactttttta gatatcgctg
    11221 caccaagtgt attattagca caggcaatcg gtcgttgggg aaatttcatg aaccacgaag
    11281 catatggacc agacacgacg cgaagcttct tagaaagtct gcatttaccg caattcatca
    11341 ttgataatat gtatatcgaa gggatctatc gtcaaccaac atttctttat gaatcacttt
    11401 ggagtttgat tggatttatt ttgcttttgt ttttacgaaa gaaaccacac cttttgaaaa
    11461 aaggcgaagt ccttttatgt tatctaatgt ggtatagttt cgggcgtttc tttattgaag
    11521 gattacgtac agacagtctt tactttttag gtgtgatccg tatttctcaa ttattatctg
    11581 ctgtgttatt tgtcggtaca ttgattctat ttatttggcg cagaaaaaaa ggaaatttac
    11641 cggattatga ccgctcatta ggaaaaaatc aacaaattat ctgattttta gagcgttaaa
    11701 aatgaaaaaa atttcaggag tggtaaaatg aattatagag tagcggtttt aggaccaggc
    11761 tcttggggta ctgctttggc acaagtcctc gccgaaaacg gacatgacgt tcggatttgg
    11821 ggacatcgtg cttcacaagt agaagaaatc aacacccaac acacgaatca acgttattta
    11881 ccagatcatt atctacccga ttccatccaa gcattcacca atatggaaga tgcagtaaaa
    11941 gacgcagatg cggtgctatt cgtcattcca acgaaagcaa tacgttctgt tgcaaaagaa
    12001 ctagtgccta aattgaatac aaagccagtg atcatccatg caagtaaagg attagaacag
    12061 ggaacacata aaaggatctc tgacatcttg ttagaggaaa tcccagcaga aaaaagaaaa
    12121 gctgttgttg ttctttctgg accaagccat gcagaagaag tagcgaaaca tgacatcact
    12181 acgatcacag ctgcaagtac agatgcaaaa gcagcaaaat atgtacaaga gctgttcatg
    12241 aataattatt ttcggatcta taccaatcct gatgtgatcg gtgtagagat gggggcagct
    12301 ttgaaaaata ttattgctat tggtgctggc gctattcacg gcttagggtt tggcgataat
    12361 gcaaaggcag caatcatgac gcgcggatta gctgagatca gccgtttagg tgtagcaatg
    12421 ggtgccaacc cgctgacctt tatcggatta agcggagtag gcgatctagt cgttacttgc
    12481 acaagtgttc attctaggaa ctggcgcgca ggcaacttgt taggacaagg gcagccccta
    12541 gaagaggtgc tagccaatat gggaatggtc gttgaaggtg tgaatactac tcaagcagcg
    12601 atggaactag cccaaataat ggaaatcgaa atgcccatca ctcaaacaat ctatgaagtg
    12661 ctgtatgaac aaaaagaaat caaaacagcc gcaaaagaaa tcatgttacg tgatgggaaa
    12721 aaagaaaatg aattctcatt aacaattttt tgaaggagcg aatgtatatg aaagtcaaaa
    12781 aagcagttat tccagcggca ggattaggaa caagattttt accagcaaca aaagctatgg
    12841 caaaggaaat gttgccaatt gttgataaac caacaatcca gttcatcgtt gaagaagcgt
    12901 tgaaatcagg aatcgaagac atcttgatcg ttacaggaaa agctaaacga ccaatcgaag
    12961 atcactttga ttcaaatatt gaattagaaa caaacctaag tgaaaaagga aagaccgaat
    13021 tattgaaatt agtagaagaa acgacagatg tcaacttgca tttcatccgt caatctcatc
    13081 caaagggttt aggacatgcc gttcttcaag caagagcctt tattggaaat gaaccgtttg
    13141 tcgttatgct aggcgatgat atcatggaag atgaagtacc attgacacag caattaatcg
    13201 atgattacga acgtactcat gcttctacga tcgccgttat gcaagttcct catgatgaaa
    13261 cttcaaaata cggaattatc aatccaggag aagtattgga agatgggtta tacaatgtca
    13321 aaaactttgt tgaaaaacca gatccaagca aagcaccaag tgatttagct attattggac
    13381 gttacttatt gactccagaa atttttgatg tattgtccga gcaacaacca ggagccggaa
    13441 atgaaatcca actaactgac gcaatcgata cattgaataa aacacaacgc gtatttgccc
    13501 gtaaattcac aggtaaacgt tacgatgtcg gtgacaaatt tggttttatg aaaacaagta
    13561 ttgaatatgg tctaacacat ccagaagtag gtgcaccttt acgtgagtat atcctgtctt
    13621 taggtaaaaa attagaagca gaaggaagca agatcgatca taatccaaaa ggaataacag
    13681 aaatcaaaga agaaaagaaa aaataaccct tttttctaac gagcttcagc tgctaattga
    13741 ataaaaagta gttgaagctc gtttttattt gtttaaaaaa cacgaaaatg ctatccttat
    13801 agaaaagaga gacaagaagg gagtttgatc atgtcaggag gagaaattgc aggattgatc
    13861 gcagcaatcg cctttgcgat acttgtcgtt tttatcgttc gtgtgttgtt gcaagtttct
    13921 aaaactttag aaaaagtaga tcagactgta gcagaagcaa atacgacgat cgaaatcgtc
    13981 acaaaagacg tagatctttt gtctagacaa gtagaaggct tgctggtcaa aagtaatgaa
    14041 ctgctcttgg atatcaatgg aaaagtcgca acgatcgatc cattgttcac agcagttgct
    14101 gatttaagtg aaagtgtatc agaacttaat cattctagta aaaacatcgc gacgaaagtc
    14161 ggcggaatcg gtaaaacgac agctaaagcg acggttgccg gaaaagtcgg tgggacagcg
    14221 atgaaatttt ttaaaaacaa aaaacatact gaaacgacag gaggaaaata aaaatggcta
    14281 aaaaaggtgg atttttatta ggtgcagtag tcggaggaac agccgcagca atcgccgcgt
    14341 tattgttagc accaaaatct ggtaaagaac ttcgggatga attagctgcc caagcggatg
    14401 atttgatgga tatggcttca gattacacag atatggcgaa agaaaaatcg actgagttaa
    14461 caggtattgc aaaagaaaaa gcgcaagatc tttctcaaca agcaggtgat ctagcaggta
    14521 gtgtcaaaca aaaagtaagt gaatcagcag atgaagcagg aagtgaatct gacgatatct
    14581 tgttaaatct taaagaacaa tcagctgact tatctaatcg tttcaaaaaa acggcagaag
    14641 atatgaaaaa acctgcagat gaattaggaa gtattgctaa agatacttca gaagatatca
    14701 tgattgatgt aaaagacgct gctggtaaag caggagatac tgtcaatgaa ggaatgtcag
    14761 aagcaaaacc agttgcagat gacacaaaag aaatgatgaa aatggcaaaa gaagatgcga
    14821 aagaagctaa aaaagaaata aaagatacaa tgacagattc atctacaaat cactaaaatc
    14881 actaaaatca caaatttata gaataaaaag gtgggagcgg actagctctc acctttttta
    14941 ctcttatttt tctaaaacta gtaattcttt tggtgtagtc gtgaatggca cacagccatc
    15001 gcttgtcaca tatacacagt cttcgatacg tacccctact ttttcaggaa tatagattcc
    15061 tggttcaaga gagaagcaca tcccttcttc gattactaag tcatttcctt ctacaaggga
    15121 agggaattcg tggacggttg ttccgatccc gtgacctaaa cggtgattga aatattcgcc
    15181 gtagccatag ctgttgatca cgtttcgtgc gatttgatca agttcacctg ctgtcacacc
    15241 tggacggacg gcttcttgtg cggcaagctg tgcttcaaga gtgatgttgt atattttttc
    15301 ttggaagtcg gttggttttt gataagcaat tgtacgagta gcatcactgc aatagccatt
    15361 ccaaacaacg ccaagatcga ataacacaag ttcattcggt gaaatcttcg tgtttcctgg
    15421 tgtaccatga gggcttgcag catttgctcc tgcaaggact aatgtgtcga aagacatttg
    15481 tgaaacacct tgttttttca attggtattc gatttctgca atgatcgctt gttcagtcac
    15541 gccttctttc actgctttaa agccaatctc aaatgcaaca tcggcccatt taccagcttc
    15601 gatcagtttg tctttttcct ctagagtttt gatcagttgt agacgttgga tgatggaagc
    15661 tagatcagtg taagaatccg ttcccgtcaa gatatcagag atagcatcga agcgctcgac
    15721 agtcaaggcg ttcttttcaa tccctacatt gccaggctga ccatagcgag cacgaagttc
    15781 ttttccgatg atctcccaag ggttttcgct gtctaaatag ccacggacat catacgccca
    15841 actactgttt tgagcatctt caacttccaa agcaggagtg aaaaggaaag gatcttgttc
    15901 aagagggata aaaagagcta gtacacgctc atgaggatca ctttcgtatc cggaaaagta
    15961 agcgatgtgg ccagggtcgc tgatataagc caattcgact tggtgttgtg ccatccattg
    16021 acgtagttca ttgattttta cgttattcat ttggcaacct actttctaaa ttaattttgt
    16081 attcaataat tgtaccactg atttattaaa agaccaacgt tctaaaaact gaaaaaagta
    16141 aaaattttca tgaaaacaga gataaaacgg ttgcaattct tgagattatt tgatattcta
    16201 ttttagaaat gtaagacgta ttttcagaaa acatataaaa tatgaatagg agaacacaaa
    16261 tggaaaagca aacaatcact atctatgatg tagcgagaga ggcaaatgtt tcgatggcta
    16321 ctgtttcacg tgtcgtaaat ggcaatccaa acgtcaaacc agcaacaaga aaaaaagtct
    16381 tggaagttat cgatcgcttg gattatcgtc caaacgcagt tgcgcgtggc ttggcaagta
    16441 agaaaacaac aacagttggg gtaatcatcc ctgatgtcag caatatgttc tttgcttctt
    16501 tagcacgtgg tatcgatgat gtggcaacaa tgtacaaata caatattatc ttagcaaatt
    16561 cagatggtaa cgaccaaaaa gaagtcaatg tattgaataa cttactggct aagcaagtgg
    16621 acggcgtgat cttcatgggt caccatatca cagacgaaat ccgtggagaa ttttcacgtt
    16681 caaaaactcc tgttgtatta gctggctcta ttgatccaga tgaacaagta ggtagcgtaa
    16741 acattgatta tgtatcagca acaaaagatg cagtaaacaa attggcaaaa agcggcaata
    16801 aaaaaatcgc ttttgtcagt ggtgcgttga tcgatcctat caatggacaa aatcgtctga
    16861 aaggctataa agaagcatta agcgaaaata acctaccata tagcgaagga ttgatctttg
    16921 aagcacaata caacttcaaa gatggtctat ctctagtcga tcggatccat aatagcggtg
    16981 caacagctgt ctatgtttca gatgatgaat tagccatcgg tattttggat ggtttattag
    17041 accgtggcgt gaaagtaccg gaagaattcg aaatcatcac aagtaacaat tcactactga
    17101 cagaagtagc tcgtcctcgt ttaacaagta tcacacaacc attatacgat ttaggggcgg
    17161 tatctatgcg cctattgacg aaaatgatga ataaagaaga agtcgaagaa aaaacgatta
    17221 tcttgcctta tggaatcgaa gaaaaaggat ctacaaaata ataaaaggac aaccattcag
    17281 aggttgtgag cctgccgttt aactctgcgt tacaaggagc aatttcaaaa aacagcattt
    17341 catgtttgat gaatattgtg actcgtgatt cggagttggc aggagaacac cgtttattcg
    17401 ggaaaagggg ttatgacaaa attttgttta atcctttttt tttgtcttaa aaaagagaga
    17461 aagtggttga aattacattt atcgtatata aaacaatccg tgtatagatg ctgcattatg
    17521 ttcaccacca tcaaaaaaat aagggactgt gtattctatt aaatcaatca tctttctcat
    17581 ctgattcttt ggttgcttga ttcgctcttg cataagctga agcggtgttc cagtaatctg
    17641 tatagttttc atcggtaccg ccaacgccaa atttaaaggc gcttttcttc ggtccatttt
    17701 tcgcccatag cgattcaact gtttttcctg gtgtttggat ggatttttta ttgacagtaa
    17761 cttttccagg tgtttgacca gtaaatccag atactttttt cttcatcaca tcagatgata
    17821 attcgaattt ctcatcagtg ccaaaaatgt caggttttgc ttggtaagct tgattgatca
    17881 gattggcaag ataattagcc gaacgtatcc ttgctttgct gtccattcca gtattgtcat
    17941 cgtgccctgc ccagctactg atggtaatag acggagtaga gacaattagc catgaatctc
    18001 ggtattcatt ggtagaacca gtttttccga cccaatctgc ttttcctaga tttccgttta
    18061 agcttgagat ggcatctttg aatggtgtag tgatttttgc attgatcaca ctgcgcatca
    18121 tgtcattcat gatcgatgcc gttgcttccg aatagatccg gacagagttg ctttcgtgtt
    18181 tataaattac atttcctgcg ttatctgtga tggaatcgat gatatagcct tcttcataga
    18241 cgccgccgtt tgctaaagcc tgaaatccat tggtctgttg aagcgtcgtg acatctactg
    18301 tacctaaagg agcagattca acgccccaat tgtcatttgc cgggtagttc atctttgcca
    18361 agtagtgctc gtaagcatat tgtttcgatc caccggaatt caacacatct tgatataagt
    18421 gataagccgg gatattgttg gaccattcta gtgactcacg gacggtttgg aaggtgttcg
    18481 atccttcgtt agtagcattg acgattttct cgccagcatt ttctccttct tgccaagttg
    18541 ttgcataatc tgatacacgg gattctgatc cgataagccc catgtcgatt gcaggtccat
    18601 aaacaagaac tggtttgatt gatgagccag cttgacgttc tgtatcgaag gcatggttat
    18661 tttgattctg actgtaattc cgtccgccaa cgaatccgta gatgcggcca gttctgttat
    18721 ccatcaatac atttccggtt tctacttgac tgccagcacc atcatctaac atgtatccat
    18781 aattttctac gccattttgc aatgcagcat agacatcttt atcgattgtc gaatggattg
    18841 tatatccttt attttggatc gtttgctgtg ccttttgata ataagcgtca ctgaccgatg
    18901 aatcagacat atcagcgttg tctttttcag ccaattgttg tgcaatgatt cttgttgctt
    18961 cattcatcac agtataatac aagaattctc tgtcagtctg ttctgcgatt tgttgtggta
    19021 gaaagtcttt tgtaaggtca taggcttttg cttcttcgta ttgttctttc gtaatttggc
    19081 cttcacgata catactgaat aaaacaaaat cttttctggc aaggccggca gaaagatctt
    19141 cttttagcgc acctgtgttc gtgtatggac tatacgtgat cgggctttgg ggtaatccag
    19201 cgatataagc agcttgcggc agcgtcacat cttttgcatc tacaccaaag attcctcttg
    19261 cagcttcctg gactccagca atgttttgtc ccttattatt acgaccaaat ggtgagacat
    19321 tcaaatacgt agcaatgatc tcatcttttg aaaagtattt ttctacttgt gcagaaagaa
    19381 tgatctcgtt tgctttacgt ttgaatgttg tttcatctgt aaggatctgc tgtttgacta
    19441 attgctgtgt caaagttgat ccaccagaag agccaatacc agtagcttca gatactaatg
    19501 ctcgtaaaac agctttagga acgtaacctt ggtgtttatc gaagtattca tcctctgtgc
    19561 tgataattgc agttttcaat aaaggtgaaa ttttatcaga tgaaatagtc gtgcgcatca
    19621 gatctgtctg gatttttgat atctctgtat tatctgcata aacaatcttt gacgtttctg
    19681 taatgtttcc tagttctgtc tgcagtgctt ttttagtcgg caattgtgtg tcttcgacga
    19741 gataggcaaa atagccagcg cctattccaa tacctagagc tgcgaacatc aaaagaagaa
    19801 cagtaataaa aacagtcaat gattgaaaaa ctctaaaaat aatcttagga acaaaccatt
    19861 tttctttttt tcttctattc tgtttttttc gagtattttt gcgtggcaaa agggtcacct
    19921 caactaatgg ttttatttcg ctaattatag caaataatag aacaaaaaaa cagacaaggc
    19981 tgtttttggc aggaatttct tttttaaaag agttaaaacg tgagaaaatg atctttttta
    20041 taaaagagtt cttaagcttt tctttagaga aaatttcagt tactatggag aacagggcaa
    20101 agaaaaatca atcattttct ttgtatatca tcttaccaat atataggaat tgttagtaac
    20161 aattgccttt caaggaggaa tccatccatg ttattaggct cacacgtcag catgagcgga
    20221 aagaaaatgc tgttaggagc agcagaagaa gcagccagtt atggatcttc gacttttatg
    20281 atctatacag gcgcccctca aaacactaga agaaaagcca tcgaagagat gaatattgat
    20341 gccggaaaag cgtacatggc agaaaacggt ctaacaaata tcgtcgttca tgccccttat
    20401 atcattaatt tggggaatac gatcaaacca gaaatgtttc cttttgccgt ccaatttctg
    20461 agagaagaga ttgttcgtgc ggaagcttta ggcgctactc aaattacact tcacccaggt
    20521 gctcatgtag gggcaggaac agaagccgga attgctagaa ttattgaagg cttgaatgaa
    20581 gttttgacaa aagaacagac ggcacaaatc gctttggaga caatggcagg taaaggtacg
    20641 gaaatcggtc gaacatttga ggaattagcg caaatcatcg atggagtaaa attgaatgaa
    20701 aaattatccg ttacttttga cacctgtcat acgaatgatg ccggttataa tattaaagaa
    20761 gacttttcag gtgtaatgga agagtttgat aagatcatcg ggttagatcg gcttaaagta
    20821 ctccatatca atgattctaa aaatccgcaa ggttcgcata aagaccggca cgccaatatt
    20881 ggttttggaa caatcggatt cgacacgctg aataagatcg tccatgatcc aatgtttgac
    20941 aatatttcga aaatcttgga aactccctat gtcggcaaag ataaaaagaa agcttacgca
    21001 ccatatggaa aagaaatcgc catgttcaaa gcacaaatat tcgatccaga agtgtttcct
    21061 gagttattag cagaagaagt gatactctaa gattttctat ctgacagcag caaaaaagga
    21121 ccaggcacat tgccttgtcc ttttttgttt aagaaacaaa ggagtgcttt ttgcagtctt
    21181 tttcatcatg catcttctcc cccctctttt taaatttaga caaacagggt atactggtag
    21241 aaaagtaaaa aaacgaaaag tttcacaagc aagtggcaaa acgtgattgg aaggacgaaa
    21301 agatgctgaa cactttaaaa cccttgatca accaactaaa aaagaaacat acatacttta
    21361 ttcttggcat agccctatta tttacaatta ttcgtttgta tttatatagt aaagcaatct
    21421 atggaacaga catgtcggca acctatgatg accagctgct gattcgctat gctcaaaata
    21481 ttttggacgg taaatggcta ggggagtata cgactacaac actttccaaa ggaatctcct
    21541 acagcttatt tttagtactt gcacataaac tgcatctttc ttatgcagtt ttgttcggca
    21601 tgttcagtat ttttgccagt atattggttg cactcgcgtt taaaccgatc gtgaagaaca
    21661 agtatcttct tttaagtttc tatttttatt ttttgttttc tccgattagt tttacacatg
    21721 aatattccac tcgaacgtat cgtaatgccc tcgtgattcc ggctgttgag atcattatcg
    21781 cttgtttact agctatttat taccgtaaat atagttccag caaaaaaatg ctgccgtggt
    21841 ttttagggct agctgtttct tttcctttct tttggttcat tcgcgaagat tccatctggc
    21901 ttcttccttt tactgtagtc gcgttaggca tcagtttcgt ccagatcttg ctaggacaag
    21961 acttttcttt caaagaagca aagaagttaa aagaacgacc atttctcctt tcgaaacaag
    22021 aatggctgaa actttcattg tttttactcc ctctagtcgg tttctccatc gtctatcagt
    22081 ggatcgaata taaaaacgag acaacatata gtattgccgc catcaatgac cgttcgagtg
    22141 gcgaatttgg acgtttgatg aaacagctga tccgaataga tgacgaaacg aacttaaata
    22201 aagaaaacag tgagatatgg gtctcgcatg ctgcattaaa taaagcatta gacgcatctc
    22261 ctacatttca tgctgtttct actcgtattg acgaattgta tacgactcat gcgtggaccc
    22321 aaggtggaaa agtaaaagaa ttaccaggag atatcatttt ttgggcattg cgagatgtgg
    22381 taagcgaatc tggttattac caaaacaatg caaaagaaac caatgatttt tggaaaaaag
    22441 tcaatcaaga attagaagaa gcctatcaaa agggaactat caaaaagaaa aaagaattct
    22501 atctgatggg atcaggggat ggaaagacga tgaatgatct gccaatcgta tttgcttttc
    22561 tgaaatcagg atatgcctat gcatggcgat acaaagattt ccatcaaggg gggaattata
    22621 gtttcggtac gcaagaacaa gtcgaacagg cccaagaatt attgaatctt ccactaatgg
    22681 ataattggat cgatagcagt gatccgagaa cacctgattt ccagttgaca aaaacagcaa
    22741 aagtcgcgaa tgtcatgata aaaatttacc aagttctggc cattcccgtg ctgattgctt
    22801 caatagcagg gatattactt atgatactag gaaccgcatt tgcaaaagct gatcgtgcct
    22861 attatagttc ctctttgatt gtagtcaccg gattaatact gacacaattg gtttttcttt
    22921 tcggcgtctc gtggttttgt tcttatgcgc cagaaaaaaa ggattatttt ttaagtgtct
    22981 acactggcgc aggcgtgcca ttaacgcaat tcatcgtagt aacaagcatg ctagttttca
    23041 gtaaattgaa tctgaaaaaa gctttatctt ccaaataaaa acatactaag attagaggag
    23101 aacatcattg acgaatgatg ttctcctcta ttttctattt ttagattata gtgaagagtg
    23161 aaagaaagtt cgaacaaagc cttgaggact atgagtccct atcaaaaacc gaacttcttt
    23221 actgtcattt tagaatcagg tttacgtatg ttggggccat gagcccgtgt ataggaaatt
    23281 ggaatcgaaa tgaagcagta aagttctttc aaaacttaaa aaggaggaaa acaaatgcct
    23341 tacattcttg cattagatgt ttcaatggga cacagctaca gtgtcctata caaagacgac
    23401 acctgcttat ttgaagacga gatcgaacac actcaaagag gatttcatgc attactcgaa
    23461 gagatccagc acttgcctga acgtccattg attgtttttg aagcaacggg gatttattcc
    23521 agaccagtcg aaaagttctt tcaagatcat cacttttctt actgtttgtt aaacccgtta
    23581 gaagcgaaaa aacagatgga agaaaacacc ttatgcagtt ggaaaacaga taaatcggat
    23641 gcccatcggc tcgcacagac tcatcttaaa aatcaacgtc agccaaaaga agtacaaagc
    23701 aatttttact tagagatgcg cgatttagcc cgtttttatc aagaaattga gaagaaaatc
    23761 actcgtctgc gcatggattt acacaactgc cttcagttga cttttccaga gcttgaacag
    23821 ttctttttaa acaggctgac cccttacgca ttgatattga tccgtctttt tccccatcca
    23881 gattttgtat tggcatctac tcggacaaaa ataaaaaata aactgatcaa cgaaacacgg
    23941 aaaaaaatct ccgcgaatcg tgccgagcaa aaggcagatc aaatcatcca ctatgcacag
    24001 tgtgcctatc cagctgttga aaaagacagt atccactgtc aaaaaacgat ctattacgct
    24061 gaacttctcc aagatttact cgaacaaaaa gaagcactgg cgacacaaat gatcaaaaaa
    24121 gccgaaggct ctccttgctt tttgttgtac caaacgttcc ctgggattgg cgcactcaca
    24181 gccgctttat tgctcggtga attaggagat atcacacgat ttaaaaccca taaacaattg
    24241 aatgcctttg tcggaatcga catccgacgg tatcattcag gtaagtatac tggccaagac
    24301 cgcatcaata agcgtggtaa tcccaaagca cggaaaatta ttttcttcac cattcgaaat
    24361 atgattcgcc agcaacgcgc agctcctaat catattgtcg attattacta caaattaaaa
    24421 aagcaaccta tccctaagaa agataaggtt gccacagttg cttgtatgaa caagcttctg
    24481 aaatgtatgc acgctatggt tagggcacat acagagtacg actatgcgta cgcggtctca
    24541 gtggaccatt aactaaacca cttacagtat accacttctt tgcccagatc gaaaattttt
    24601 tacgaacggg gctttatttg gtgtgccttg attttgtcgc tttcgtttat gagctatttt
    24661 tcttacacct tttacttgac taatcgtagg aaagggaact gtgacaaaag tcttgtcgca
    24721 gttccttttt ccgaataaac ggtgctcaaa agcttgcatc tgcggtaata agtccaacca
    24781 agttaaaaac ataaaaagct gtttttactt ggctgttctt attacttgat gcaaggcagc
    24841 tttttcacaa cctctgatac acggtgttcc agaagtaact tcttcggaaa taagccgaaa
    24901 tttcacaaaa atttgaaaag caattttctt aaattccttc ttatttcttg aagctgccca
    24961 cttctgacac aacctccttt gtgtaaaaga atcagtttct actcgatttc ttctatcgtt
    25021 tcctgcaaac gctgttcata ttttttgttt cctttatata aatcaccaat cgtccatgcc
    25081 aacaggagaa ggacaagaac aatgattaca taagcgattt gatcagccaa tgctagttga
    25141 gctgaggtgg cttgctcgcc gaagaaactt tcgatttgac ctggtaatcc tcgtaaattc
    25201 aagtaagtca gactaatcac agagaaccag ccaagtagtt ttacaacaaa tgaatttttg
    25261 aatcggctcc ccatctccgc ttggctattg gtcatcatca gtaaaggaat catcgagaat
    25321 ggcaatgcaa aagccagaaa aacttgggat tcattcatca agttattcaa agcggtatgt
    25381 tcttcgatcg ttccttttgt acttgtaaac aaaacacaaa tcaatacagg aatcacagaa
    25441 agcaatcgtg tgactagtct tcttagccaa attgggatac gcatatggat gaagccttcc
    25501 atgatgactt gaccggtcaa cgtaccagta atagtagagt tctggccaga agcaagaagt
    25561 gctacagcaa ataaagtaga caagatacca gattttgcta cagcaatcaa gataccattg
    25621 ctcatagctg atggatcaga taaagcttca tacagaccaa aaaaggaagg atcttggaca
    25681 gaaccggttt tgaatacagc cacacccatg atcaatagca gtgcattgac tagaaaagcc
    25741 attgacaact ggatattaga atcccaagta gaaaagcgta ccgcttgtgc tacatcttct
    25801 tcgtcttggt gatcgatctt ccgagtttga gaaactgctg aatgaagata taagttatgc
    25861 ggcatgactg ttgcaccaat aatccctaaa gctccagtca gcggagtttc gccgccgatg
    25921 accggtgagt ctgagaatgt gtgactgtta gggataaatc cggcaaacaa actgtgccaa
    25981 tcagggttag acaagccaac ttgatagacg aaaacgaata aaatgacgaa aatcaagcag
    26041 acaaccaaag cttcgatttt acgaaacccg acttttgtca gcaataaaag gacgaaaaca
    26101 tctaacacag tgataaatac ggcaattacc aatggaatat caaaaagcag gtagagggcg
    26161 attgctgcac caatgacttc tgcgatgtct gttgccataa tggctaattc agtcaagatc
    26221 cataaaatga cacccaatgt cttacttgtc cgtgctcgga ttgcttgggc caaatccatt
    26281 tgggtcacga ttcctaattt tgctgccata tattgtaaaa gcatagcaat cagactagac
    26341 atcaaaataa ctgacatcaa taaatattgg aaattttgtc caccagtgat cgaagtggac
    26401 cagttacctg gatccatata accaactgct actaatgcac ctggtccaga gtaagcaaga
    26461 agtgttttaa aaaaactttt tcccttgggt acatccactg ttccatttac ttcagctaaa
    26521 gataaaccat ttgtatgttc aataagtcga tgcttatgaa attgtttgtt ggattgatta
    26581 ttcaagaaaa aaccaccttt cctatttatc tacgattaca ttctacacct cagaaagaaa
    26641 aaattaaaga aaaagatttg gtatgcctaa ttttttttcg tggcgtgtct tgctggttaa
    26701 tgaaagaaat tttgttcttc tctaaaaaaa ccactatttt ttgcatgaaa ctaaagaata
    26761 cgcctttctt ttttcaataa actttagtaa aataaatcat tgagagcaat tcggaaatag
    26821 aaaggagaga tttatatggt atcaacaggt attgtcgtac ttattgctat tattgctttg
    26881 ctaatcggcg cagtaggtgg ctttttccta gcgcgtaaat atatgaaaga ctatttagaa
    26941 aaaaatcctc ccgttaatga ggacatgttg cgatcaatga tgatgtcaat ggggcaaaaa
    27001 ccatctgaga agaaaattcg ccagatgatg cagcaaatga agaaccaagg gaaaaaatag
    27061 gttctgaccc aaagactttt tgcgggctga ttttttcagt ccgtttttta tttcgtaatt
    27121 tgttagacta ttcagactat tcagcaaaaa agacaagcac agacaatcct atgctcttga
    27181 taaagacaaa ggaggagtaa aatgtcgatt tttagaaaat taggttggtt ttttcgacag
    27241 gaaaagaaac attatttaat tgggattttc tccctattcg cagtggcctt ggtacagtta
    27301 gctcctccaa aagtgattgg gatcatcatt gatgagatcg ccgataaaaa tttatcaata
    27361 aagatcattt cctggtggat cttattattg atccttgcag ctctcttaca atatcttttt
    27421 cgttatatct ggcggacgaa tatttgggga agtgcagctc ggttggagaa agaacttcgg
    27481 cagcagctat tcaaacattt tacagaaatg gacaatctct tttaccaaaa atatcggact
    27541 ggagatttga tggctcatgc aacgaatgat ttgaatgcaa tccaaaatgt agcaggagct
    27601 ggtatcttga cctttgcaga ttcagtgatc acgggcggaa caacgatcat tgcgatgatt
    27661 ttgtttattg attggcgctt aacactgatt gcgctgattc ctctgccttt actagccgtt
    27721 acttcacgag tgctggggtc aaaactccac gatgcttttc gtgattcgca agaagctttt
    27781 tctagtatca atgataagac acaagaaagt attactggga tcaaagtcat taaaacattt
    27841 ggacaagaaa aagaagatct cgcggatttt gaagaaaaga ttgaagatgc aattattaaa
    27901 aacaaacgag tcaatttttt agactcctta tttgatccat tcattacctt gattatcggt
    27961 ctgtcttatg ttgcaacaat tattttaggt ggaaagtatg tcttggaagg cacgatctca
    28021 atcgggcaga tggtctcatt tattagctat atcggtatgc ttgtttggcc gatgtttgcg
    28081 attggtcgat tgttcaacgt attggaaaga ggaaatgctt cttatgatcg cgtcaatgaa
    28141 cttttgcatg aaaagacgca tatcgtggaa caactgggtg cagtgcagac tccggcaaaa
    28201 ggcgagctga atgtagctat ttcctctttt aactatccga aagaagaatc accagcatta
    28261 gaacaaatca aatttgcgat ccaagaagga gaaacattag gtattgttgg gaaaactggt
    28321 gcgggaaaaa cgacaatcat caaattactg atgcgtgaat acgatgatta tcaaggaaaa
    28381 attcaatttg gcggatgttc gatcaaagaa tattcattga atgctttatt aggatcaatc
    28441 ggctatgtgc ctcaagatca cttcttgttt tcgatgacca ttcgagataa tatccgtttt
    28501 tctaatccaa aactttcaga agaagaagta gagcatgcgg cttctttagc atttatcaac
    28561 aatgaaatca aggaattacc aaaaggttat gataccttag ttggagaacg tggagtctct
    28621 ttatctggcg gacagaaaca aaggatttcg attgctcgag cattgatcaa aaatcctgaa
    28681 ttgctgatct tagatgatgc actttctgca gtagatgcca aaacagaaga agctatcttg
    28741 cataatttaa aagaaataag aaaagagaaa acaaccatca ttgcagctca ccgtttaagc
    28801 agcgtgatgc atgcaaaaga aatcattgtt gtcgatcaag ggaaaatcat tgaacgagga
    28861 acccatcatg agctgcttgc attaggcggc tggtatgaac gaatgtggga gaaacagaaa
    28921 ttagaagcga agatagaagg aggcgaggcc tgatggatga aaattatcaa tcggaatgga
    28981 caaaatcgat tccacttaaa gaacagaaga agatcatcaa acgactgatg aagttcgcca
    29041 aaccttttag aagaacgttc atcgttgcta tcttatttgc gtttgccctg tctgtgatca
    29101 atgtcctatt gccaaggatc atccaaactt ttatggatga tcatctggct aaacagtcgg
    29161 ctacgacaca agttattttg ttttttgctg gtatgtactt gtttggagtc atagtcaaaa
    29221 gtatcatttg gtttttccaa tggtatttgt attccatggc ttcattgaag acctatcagt
    29281 atgttcgggt aagattattt gaaaagctgc atacactagg tatgcgttat tttgatcaga
    29341 caccggcagg atcgactgtt tctcgagtga caaatgacac agaaacgcta tttgaatttt
    29401 ggtatgtctt tttgatggta ttgactggga tctttgcagt cgtttcttcc ttcattgcca
    29461 tgtttcaaat caatggagaa attgccttgt ggactttggt gttcttgccg attttaggaa
    29521 tcgtcatctg gtattaccag aaattcagtt ctcgtattta ccggaatatg cgggaaaaat
    29581 taagtcagct gaacacgaaa ttgaatgaat cgatttccgg catgcgtatt atccagcagt
    29641 ttcgccaaga agctcgttta gctaaagaat ttgaacaagt gaacaacgag tatttagaca
    29701 cgcgctatgc gatgatcaaa acaaattcga ttctgttaag tccgatcatc aattttctat
    29761 atgcattggc gattgcgttg gcgttgactt tgtttgggat cgatgcgctg cattctcccg
    29821 tagaagttgg actgatctat gcatttacga cctatgtcca gggatttttt aatccaatgt
    29881 ctcaaatgat ggactttttg agcaccttta cagatggaat ggttgccggt agtcgtattt
    29941 tgaaaatcat ggatacagaa gaatatgcac cgcaacaaaa tcctggagca gatcaagcga
    30001 ttacttcagg taagatcgag tttcgcaatg taagcttttc ttatgatgga gagcacaatg
    30061 tattgaacaa tatctctttt gtcgctaatc cgggagagac cgttgcatta gtggggcaca
    30121 ccggaagcgg aaaaagctcg atcatcaacg tattgatgcg gttttacgaa ttttatgaag
    30181 gccagatctt gattgatgat catgacattc gagaatatcc aatggaagag ttacgtaaga
    30241 aaatgggatt ggtcttgcaa gatgccttct tgttttatgg agatatcgca ggaaatatcc
    30301 ggatgatgaa tccaactatc acagacgaac agattcgcca tgcagctgag tttgttcaag
    30361 caaacaagtt catcgatgaa ttaccaaaag gatatcactc aaaagtgatc gaacacggtg
    30421 ccagctattc tagcggacaa cgacagctga tcacttttgc gcgaacaatc gtgacagatc
    30481 ctaaaatact agtattggat gaagcgacag caaatatcga tactgaaaca gaaggattga
    30541 tccaagaagg attgacaaaa atgcgacaag gacggacaac gattgcgatt gcccatcggc
    30601 tgtccacgat tcgggatgca gaattgattt tagttttaga caaaggtcat atagtagaac
    30661 gtgggaatca tgaaacactt ctagcgcaaa atggtttgta tgcagatatg tacaaactgc
    30721 aaagcagtgg tgtgtaaaaa gtggttgtga cagggctccg ttcagcttta ggtgataaga
    30781 aaaaaattgt aaaaaaggct ttccagattt ttgcataaat ttggcttatc accgataagc
    30841 tggtactgga acaccgtata ttagaagttg ggacagtagc atagtagcat tttgacctaa
    30901 gcgctagagt gaaaataaaa cagagcttcc cagattcttc atctgtgagc gttagtgtcg
    30961 taattaccag atttaaaaaa aatcacgaca gctagtcaga agtgcccaat agccgctaag
    31021 aaagcgttga caaaagtgct tgctttcgat aatataaaga aaacgataca acttggatag
    31081 tgattgcctg atgcaagcta aacctgatga gtctcccatg gttccatgga cggctttttg
    31141 ggtttttctt tttgttttgg atacagccct atatatcatg gaaaggagta aaacatgctg
    31201 attgagaaag tactgaataa caacgtcgta ataaccaggg atgaaagaaa tcaggaaatg
    31261 atcgtgatgg gaaaaggttt ggcattcaaa aagaaagtgg gtgacccgat ttttgactca
    31321 tgcatcgaca aaaaatttca gttgacaaat gacggacttt cacaacagtt ccaagaattg
    31381 gcacaagcga ttcctcttga gtacttagaa atttcttgtg aaatcattga atatacaaaa
    31441 gaggctctac aagtccagtt gaatgattcg gtgtatattg cattgacgga tcatttgtat
    31501 acggctatcg aacgtcacaa aatgggaata tttgtaccaa atgtattgct gtatgatatc
    31561 aaacaactat ttcctaaaga gtatgccatc gggaaaaaaa cagtgaagaa aatctcggat
    31621 aaataccaca tcaagttatc agaagatgaa gccggattta tcgcattgca tttagtcaat
    31681 gcacaaggca ttcaaagcca acaagacaat acctacctgt ttactacaac aatacaggat
    31741 attctaaata tcgtccgcta ttactataag attacatttg atgaagattc agtccatttt
    31801 tttcgattcg tcacacacct acgttttttt ctgacacgcg tcctagatgg agaaaaatca
    31861 gaagtgggag aagtttctga ggaattgtac caggttattc aaaaaaaata taaggatacg
    31921 tttggttgcg ttgagaaaat agcagacttt ttagccgaga tattcaacta ccagatgtcc
    31981 acggacgaaa aaatgtattt aacgatccat attgcgcgtt tagtgcatga gaatcgttgt
    32041 aaataaataa aaaaaggagg ataaattaac aagaacgcat gaaataaggg tagtgacatt
    32101 cagttggcta aaccttccac taataaattg gagggaatag aaatgggaaa atatcaagaa
    32161 ttagcgagca aaattgtaga aaatgtcggc gggaaggaaa atatcaatgg tttgacacat
    32221 tgtatcacaa ggcttcgttt caaattaaaa aacgaagaaa aagcaaatga tgagatcttg
    32281 aaaaatatgg acggtgttgt gacggtaatg cgagcgggag gacagtacca agttgtcatc
    32341 gggaatcatg tgccagtcgt gtttgaagag gttataaaag caggaaacct tacttttgat
    32401 gaggctgttt caacagaaaa aatgagaccg tttgatatgc ttattgatgg aatatcgggc
    32461 tgtttccagc cattccttgc tattctagct gctggtggga tgattcgtgg actgacagca
    32521 ttacttgtct tcttaggcgc atttgaccgc ggttctggca catttgttat gtttgataat
    32581 atcggtgatt ctgtattcca atttatgcct gttattatcg gtttaacagc tgcccgtaaa
    32641 tttaaagtaa atgaattcgt agggatgttg cttggggcag cattaatgaa tcctagcttg
    32701 tcgctggaag ctttgagtgg tgcagcagaa gcaccactga ctaccatatt ttctggcact
    32761 atttttgaag cacctattta tcaaacagta ttcggcattc cctggattgc gcgtaactac
    32821 gcttcttctg tcattcccat tatctttatt gtgttgttag ctagccaaat tcagaaacca
    32881 attaaaaagt tagtacctga gatgatcgcg aatttcttcg ttccattctt caccgttctt
    32941 attacaatgc ccttaggttt tttactcgtt ggaccagcat tcacattcgc aactgatatt
    33001 ttaatggctg gatttgaaac acttttagca ctttcgccag ttatttatgg agcaatcgta
    33061 ggcttcttct ggcaaattct agtgatgttt ggtctccatt gggcaatcgt accaatggga
    33121 ttgatgcaat tttctgtgaa tggttggcaa aatatcatga cacctgttgc agtagtgtct
    33181 tttggacaaa ctgcagcact tactgcactc tactttaagc ttagaaaccc aaaagacaaa
    33241 gcaatcgcaa taccagccat tgtttctggt attgtgggga ttacagagcc agctatttat
    33301 gggtttacat tgccacgtaa aaaaatattt atttttacct gtgtcggtgg tgcgttaggg
    33361 ggcgcgtata gtggattaat gaatttaact tcttggaatc caggtggatt aggcatcttt
    33421 acaattccca actatattag accagatggt gatttaacgg atgtgattaa tgtattgatt
    33481 ggaatcgcca ttgcgatggt ggtatccttt gcgctgactt ttttcttttg gaaggaggaa
    33541 gcaggtgaaa cagatgatag acagaaaaga tcaggtaaag aaattgtaaa aacaccgata
    33601 caaggacaaa tcgctccact gaatgcagca aaggatgcag cttttgcaca aggaacacta
    33661 ggtcgaggaa tcttgatcta ccctgaaaaa ggagaagtac gtgccccttt tgacggaaca
    33721 gtcatgaccc tgttcccgac gaaacatgca atcggaatgg tttctgaagc aggtctggaa
    33781 ttgctgattc atgtcggatt ggatactgtt cagttggaag ggaaatattt tgaaagcttg
    33841 gtgcagcaag gagaaagagt gaaacaaggc gatctgttgc tccgcttcga caaaaagaaa
    33901 atcgaagagg aaggatacag tttagaaaca cctgtgatcg tcaccaatta cacggattat
    33961 ttggatattt tggaaaatca aggggagacg gtcgggccag acgatgcact tatcaccgca
    34021 ctgacctgaa cggttaggtg aaagaatgga ctaggcttaa ttattctttt tagtccactt
    34081 ctttattttc aaaattgaaa ggctctttca tgatggctga gctgataggg cgtttatcaa
    34141 atttttgtcc tacagaaatt agatggacta aattctgttg ataattttct gcaaaaacac
    34201 aactatataa cacgtctaga agataacaaa tcgatgtatt gatcgtaaaa ttaccaattt
    34261 tcgaatacag tcgttcgcgt gtcgtaagtc gcaaagcggc tgtactcatt gaagatagcg
    34321 ttgaatcacc gatactggtc aaagctaaaa ttggaacatg attttgtttc aatatttctg
    34381 cggtacgaag gatcacattg ttttcacccg tataagaaat cagaatcccg cacatatcac
    34441 tcgtgcaatt gtacgcttca tagaacgatt caccaaaagt ggtgacaatc gtgacatcca
    34501 ttttgatgcg cttcattttc agcatgaaat cttgagaaat caaagtattc gagttactgg
    34561 cgaaaatcac gatttttttt gcttgaagca ttagttgttt ggctttttgc agttggtcat
    34621 gatgaatgag agaaagtgta tcttgaatcg tcatctgttc taaagaagcc attttatttg
    34681 cgatcgtcat aataccgtct gtggtggaaa aaggaagatt cgcatctacg tcttgaaaat
    34741 tcccttcaag ataggctgtt tcagctaaaa aagcattacg aaaactgacc cagccatcaa
    34801 aacccatttt ttttgctaca cggatgagtg tggacgggtg gacataacat cgctcagcaa
    34861 tctcttggat ggtcatttcg ccaagtgctg gagaatcgct taagagaaac tgaatcactt
    34921 cattttctga aggagaaaag gagatttctt tgattttttc acgtaataac atgtagatac
    34981 cttcttcttg tttttttacg taaattataa cttttttgaa aatgatttgt aaacggattt
    35041 atgttatata gcttaataaa gacatttttt gacaagatat ttacaaaaat ccagtagaaa
    35101 acactaactt ttgtaaatgt tactggaaag aaacgaattt ctattgtttg ttttgtttac
    35161 aaaaaagata ataaaagtgt aaaaagtaaa ggagtgagaa catggcaaaa ggaatcaaaa
    35221 tcgctacgat tggtggaggc agcagttaca cccccgagtt gatggaagga tttatcaaaa
    35281 gatatgagga attaccgata cgagaaatct ggctcgtaga tgtagaagaa ggaaaagaaa
    35341 agcttgagat cgtcagtcag atgtctcagc gtatgtggga tgcttctccg tatgaagtca
    35401 aaatctatgc aactctggat cgggaagaag cattgaaaga tgcggatttt gttacgactc
    35461 agtttcgtgt cggtcaatta gatgcacgaa tcaaagacga gcggatccct agttattatg
    35521 ggatgattgg gcaagaaaca aatggtgctg gcgggatatt caaagctttt cgtaccgttc
    35581 cagtggtttt ggcaatcgtt gaagacatga agcgtttatg tccaaatgct tggctgatca
    35641 atttcgcgaa cccaagcggg atggtgacag aagcagttat cagatatggc aaatgggata
    35701 aagtgatagg attatgcaat gtgccagtaa tggcgatgat gacagaacca acaatgcttg
    35761 gcaagaaaaa agaagagctg atctacaagt ttgccggtct aaatcacttc cattggcaca
    35821 aagtagcaga taataaagga aatgaccgca cggcagaatt gattgatcgt ttatacgatg
    35881 aagacaatgg attgccgaaa aatatctttg atatcccgtt tttcaaagaa caattaaaac
    35941 aaatgaacat gatcccttgt ggctaccacc gctattacta ccgtgaagaa gaaatgctgg
    36001 aacatgcttt agaagaatat caaacgattg gtacaagagc gcagcaagtg aaagaaacag
    36061 aagcagagct gtttgaatta tacaaagatc cagaattgga tcataaacct gaacaattgc
    36121 aaaaacgagg tggtgcttat tattcagatg ctgcctgtga aacgattgct tcgatctatg
    36181 gaaataaaga aacacagatc gtggtatcta caaagaatga tggagctgtt cctgatctgc
    36241 cggcagattg tgtagtagaa gtcactgcct atgttggcgc acaaggcgca cgaaatgtag
    36301 cgtttggttc ccttcctgct gctgaaagag gctggttgca agtaatgaag aatatggaat
    36361 tgctgacgat cgaagcagct gtgactggtg attatggaac agctttacaa gcgtttacga
    36421 tcaatccgct tatacgatca ggaaagacag caaaacggat catgaatgag ttgtttattg
    36481 cacatcagca gtatttaccg caattcaagg aaacaatcag ccggttaaaa gcagaaggaa
    36541 tcgaagtcca agatgaactg gcaagagaat tatcaagcaa tacacatgta atggaggaag
    36601 tatgatggga ttcagaaaag attttttatg gggcggagct acagcagcca atcaatgcga
    36661 gggcggttat gatgaaggcg gacgtgggtt agcgaacgta gatgttgtgc caatcggaga
    36721 agaccgtttt cctgtcatta ctggaaaaaa gaaaatgttt gaatttgatg aaaatcattt
    36781 ttatccagca aaaattgcga tcgatatgta tcatcattat aaggaagata ttgctttatt
    36841 tgcagaaatg gggttcaaga cttatcggat gtccattgct tggagtcgta tttttccaat
    36901 gggcgatgaa aaagagccaa atgaatctgg tttgaaattt tatgaggatg tctttaaaga
    36961 atgtcaaaag tacgggatcg agccgcttgt gacgattaca cattttgatt gtccgatgca
    37021 tttgatcaaa gaatatggtg cgtggcgttc cagagaactc gttggttttt atgaaaatct
    37081 gtgccgagtc atcttcaatc gctataaagg acttgtcaaa tattggttga cattcaatga
    37141 gatcaatatg atccttcatg caccattcat gggcgcaggg ctgtattttg aagaaggaga
    37201 aaatgaagaa caaatcaaat atcaagcggc acatcatgag ttggttgcaa gtgccatcgc
    37261 aacgaagatt gctcatgaag tagatccgga gaacaaagta ggctgtatgc tggcagcagg
    37321 agcatattat ccatacactt gcaatcctga agatgtttgg gcttctagaa aatcagatcg
    37381 agaaaattat ttcttcattg atgtccagtc acgaggagaa tatcctgctt atgcattgaa
    37441 agaaatggaa cgaaatggca ttcagatcaa aatggaacct ggggatgccg cattgctgaa
    37501 agaacatact gttgatttta tctccttttc ttattattct tctcgagttt cgactactga
    37561 caacgaactc ttggaacaga ctgcaggaaa tatctttgct tctgtcaaaa atccatatct
    37621 ggaagcaagt gaatggggtt ggcaaattga tccattaggc ttgagaataa cgatgaatga
    37681 tatttatgat cgttatcaaa aaccactatt tattgtagaa aacggcttag gtgcagtcga
    37741 tacgcccgat gagaatggtt atgtggaaga tgactatcga atcgactatc tggcagcaca
    37801 tatccaggca atgaaagatg cagtagaatt agatggagtc gatctattag gctatacgac
    37861 ttggggatgt attgatttag tatcagctgg tacaggtgag atgaagaaaa ggtacggatt
    37921 catttatgtc gatcgtgaca acgaaggaaa tggcacatta gcccgttcga agaagaaatc
    37981 attcaactgg tataaaaaag taattgattc aaatggagaa aatctttcga atgattgatc
    38041 aatgatttat aaaagtctat tgtttttcag cggatttttc gagtataata aagctattcg
    38101 agaaacgcaa gcagaacaat agactttttt tcgcattggc tgtaaagtat gcttacttga
    38161 ttaagtaaag gagaatctac atatgtatga tgtaatcgtt attggcgcag gtcctgctgg
    38221 gatgactgct gctttatatg cttcacgttc aaacttatcc gtattgatga tcgaacaagg
    38281 cgcccctggc ggccaaatga acaatacggc agaaatcgaa aactatcctg gtttcgattc
    38341 aataatgggt cctgatctag cttataagat gtatgaaggt gtttcaagat ttgggacaga
    38401 aaatgcttat ggaatcgtgc aagatatcaa ggatcacggc agccacaaag aagttatttg
    38461 tgaagataaa acttacgaag gaaaaacagt cattatcgca acaggctgta tccaccgtaa
    38521 attaggcgta cctggcgagg aagaatttgc tggacgtggc gtttcttact gtgcagtttg
    38581 tgatggtgcg tttttccgta acaaacgtct agtagtgatc ggaggaggag actcagcagt
    38641 agaagaagcc atctatttga cacaatttgc ttctgaagta gtcatcgtcc accgtagaga
    38701 tgaattacgt gcacaaaaga tcatccaaga ccgtgcattt gcgaatgaaa aaatttcctt
    38761 tatgtgggat acagtcgttg acgaaatcgt tgggaatgaa atggtagtga caggtgtgaa
    38821 agcacgtaat gtcaaaaccg gcaatgagtt tgatttggca gcagacggag tattcatcta
    38881 tgttggactg gatccattaa ctgcaccatt tagagaagca gggttgacga acgaagctgg
    38941 ctggattcca acagacaacg aaatgaagac gaatatacca ggcgtttttg ccatcggaga
    39001 tgttcgtgaa aaagatttgc gacaaatcac tactgctgtt ggtgatggtg ggatcgctgg
    39061 acaacaagtg tataaatact tggaatcttt agaagaaaca actgcataag tttaaaaaga
    39121 gtggaagaac ggtttaattg ttcttttact cttttttttc gcgtgaaatc tactgaatcc
    39181 gatttatgcg aatacttgca accgtgcttg ataaaagaat cctttcttga tttaagcgtt
    39241 ttttggtcct catactttca tatctaataa gtgaatgcta tacttattaa gaaccatatt
    39301 tcagaaagag gtgttatttt catgtcttgg gaacaagtgt atgaacaatg ggtacatgaa
    39361 gaaaatttag aagaaaactt aaaaaaacaa ttaaatgatc tgggtgaaga tcctgaaaaa
    39421 cttgaagatg ctttttatgc accgttggaa ttcggtactg caggcatgcg gggaatctta
    39481 gggcctggga tcaatcgaat gaacatctat acggtaagac aagcaacaga aggacttgca
    39541 cgtttcatgg atacacaagg cgaagaaaca aaacgccgag gtgtcgctat cgcttatgac
    39601 tcacgccatc aatcaccaga atttgccatg gaagcagcca aaacattagc acatcacaat
    39661 atcccatctt atgtattcga aagtctacgt ccaacaccag agctttcttt tgcagtccgt
    39721 catttgaaga cgtttgcggg aatcatggta accgcatccc acaatccagc agcttacaac
    39781 ggatataaag tctacggaga agatggggga caaatgcctc ctgcagacgc agatgcattg
    39841 acgaaatatg tccgtgaagt cagcaatccg ttaaaagttg aagtattatc tgacgaagaa
    39901 gctgaacata gcggattgat cacgatcatc ggagaagaag tggatgccgc ttatctagaa
    39961 gaaatcaaag cagtaacgat tgatcatgaa ttggtggaaa caatggggaa agatttgaaa
    40021 cttgtgtaca caccacttca cggaacagga aaaatgttgg gcgaacgtgc gttgaaacaa
    40081 gctggattcg aacaattcgt actagttcca gaacaagctg tcgcagaccc agatttcact
    40141 acagtcaaat caccaaatcc agaagaacac tctgcttttg agtatgcgat acgacttggc
    40201 gagaaagaag gcgctgattt gctgattgca acagatcctg atgcagaccg tttaggtgca
    40261 gccgttcgtt tgccaaatgg ctcctatgaa gtattgaccg gaaaccaaat cggagcactg
    40321 tttgctcaat atattttgga agcacaccaa tcgcgaggca ctttacctga aaacgcagcg
    40381 gtattgaaat cgatcgtttc tagcgaatta cctacagcaa ttgcggaaca ctatggggct
    40441 accatgttca atgtattgac aggattcaaa ttcattgctg aaaaaattca acaatttgaa
    40501 gaagatcatt cccatacttt tatgttcgga ttcgaagaaa gttacggtta tttagttaaa
    40561 cctttcgttc gcgacaaaga cgcgatccaa gcattgctct tattagcaga agtagcagct
    40621 tactataaaa aacaaggcaa aacgttgtat gatggcttgc aaacgatttt tgaaacctat
    40681 ggctactacg cagaaaaaac gatttctgtg acaatgagcg gacaagaagg ttctgcgaaa
    40741 atctctgctt tgatggaaaa attccgtgaa gaagcaccaa cagaatttgc cggagcaaaa
    40801 gtcatccaaa cagaagactt caaagagttg acgagaacag accgtgaagg aaacgtagaa
    40861 aaactaacga caccgccatc tgacgtattg aagtatacgc tggaagaaaa tggctggatc
    40921 gctatccgtc cttcaggaac tgagccgaaa atcaaatttt atatcggtgt aaaaggaaac
    40981 tcttcagaag acgcagctga aaaagtagcc gcttatgaaa cgattatcca aaagatgaca
    41041 gaagaataaa aaaacttgag actgatggaa aaagtggtaa actttagaag tcagtctttt
    41101 ttcaagttgg aggtgaatgg attgccagac acgcaaaaaa caaaagtaga gaaagtcagc
    41161 caactattca aaatgttgag tgaccccact cgtctcaaaa ttctgctgta tctgaaagac
    41221 ggggaacaaa atgtgacagc aatcatccaa gcagtggaaa tggaacaatc tgctgtatcg
    41281 catcaactgc gtttattaag agaaaaccat gtcgtcaagt cccatcgtga gggaaaagcg
    41341 attttgtata gtcttgatga ttctcacgta ctggatattt tgaaccagac actcaaacat
    41401 gtggaacatc aataacgata ggtgcaaata gagacaaact ggactgtgtc aacgaatctt
    41461 cttcgctgac acagtccagt ttttttaaag aaaaattgtt agtctgtttc ttcggtggtt
    41521 tcagttccat aataactatg gtcttctagg tctaaagcat tcaaaataag cgaagctgtt
    41581 tcttcaatag ataaagaagc gacattgatt actacgcagc ccaatttttc ataaagatca
    41641 ttcgcaaaat cgagttcagc tcgtattttt tcgatatcgg aataagcagt atcaggattt
    41701 aatccgtaag agcgcatccg ttctttacgg atattgttta aaatatctgg gttattcgtc
    41761 agtcccacga tttttttagg atcgatctcc caaagctgtt tgggaatatg tgcttgtggg
    41821 atcaaaggta gattggcaac ttttaaattt ttgttagcta aaaacaagct caaaggcgtt
    41881 ttggaagttc gggatacgcc tagcaaaacg acatctgctt ctagaaaccc acgaggatct
    41941 ttcccgtcat cgtattttac agcaaattcc attgctttga tccgtttgaa atagttctca
    42001 ttcaataaat gaagggcgcc aggttgccga atgggcttga taccagttaa gcgctcgatt
    42061 tctgatatcg gcggagtcat cacatcaaaa ctaaataatt gatgttcttc acaaaaagaa
    42121 cgcgtcatct cgatcaattc ttgattgatc aatgtgtgca ggacaagagc tttttcttct
    42181 agtgcatctt gcagtgcctg catcaatgtt ttctcatctg tcacaaatgt tctgcggaat
    42241 aaattgaact caacgctagg atattgggcc atagtggctt gcgctagttt tgtcgcagtt
    42301 tctccagcag agtcggagat gacaaaaaaa gtaacgattt ctgtagaatc ggaagacatg
    42361 gataaaacct cacttgcatt ttttttatgt ttattatacc atactctaga atgtgtactt
    42421 cgtaatcatt ttgatttgga ggaataagtc atgaaaaaac agacgttgat cgaacaatca
    42481 ctagaaacat tgaaaaataa cggttttaaa tatactaaaa aaagagaagc attgttaact
    42541 tatttagtga agcgcaatcg ctacgtatcc gctaaagaag tttttgacta tatgaatcag
    42601 gaattcaaag gagtaagtta cgatacgatt tatcgaaatc tccatgattt tgcagaaatc
    42661 gatttactgg aagaaaccga tttaaatgga gagatgaagt ttcgttttca ttgctgtcaa
    42721 ggggaaatcg gccatcacca tcactttatc tgtacggtgt gcggaacaac gaaagaaatc
    42781 catatgtgtc caatgaatta tttcgaagaa cagctcggtg gatgtacgat cgaagggcat
    42841 agattcgaga ttttcggaag atgtgaaaat tgtcaataag gatttaaata aaataacatt
    42901 tgataatttt aaaaaaaagc aagatttcct tgacggtcaa aacagcatta gatataatat
    42961 ttacaggaca gtcttgtttt ttgagatata tttcaataac aattacggtt actttttaag
    43021 ctcggaggga gggaattaac atgtcaaaaa cagtcgttcg caaaaacgaa tcacttgacg
    43081 atgctcttcg tcgcttcaaa cgttccgtgt caaaagcggg tactttacaa gaatctcgta
    43141 aacgtgaatt ctacgaaaaa ccaagtgtaa gacgcaagaa aaaatctgaa gcagctagaa
    43201 aacgcaaaaa attctagttc tgtgatgaat tggagttggt agtgtgtcac tactaagtag
    43261 attaaacgat gacatgaaaa cagcgatgaa agcgaaagat aaggaatctt tacaagtcat
    43321 ccgaatgatc aagtcatcta tacaaaacga gcagattaaa gaaggtcacg acttgacaga
    43381 agaagaagaa ttaacggtgt tgtctcgcga aatgaaacag cgacgtgatt ctttgcatga
    43441 gtttgaagaa gcaggacgtg acgatttagc tgaaaaagta aaaagtgaaa ttgtgatagt
    43501 cgaaaaatac atgccggaac aactttccga cgaagaaatt cgacaacttg ttcaagaagc
    43561 aatcacgcaa actggtgctt catcaatgaa agaatttggc aaagtcatgg gtgcgatcat
    43621 gcctaaagtc aaaggaaaag cagatggaaa ccaagtaaat gccattgtga aagaactatt
    43681 acaatcttaa ttttatcatt taaactgcgg acaatcattg tccgcagttt ttttgtgctc
    43741 gtaaaaaaga gatctaaaaa atagctagac gaaagaatag gattctttca tctagctgtt
    43801 tttttcctgt ttaatatttc ttatgttaaa ttgtgtttga tctggttatt cttctggtag
    43861 ttcatttgct tcttgtttat accctgatag gcgataggcg taatagaaga gtaagctgcc
    43921 agcataccca agtaacgttg ggaccatcca gccaagtccc aatgcagcaa aaggaacgtg
    43981 atgatgataa aattcgagca tgcttgctac aactctttgt tgactcacta aagcaggcga
    44041 atttgccagc atatccaata cggcgggaac agcagcaaac aacatcgtta cttgatagac
    44101 aaatggtgtc ttttggaaaa attttgctgt taaggaaagc aaaatcaacg caagcgacaa
    44161 tggatacaaa agcatcaata ctggtaaaga ccattggatg atattgtcca aaccagcatt
    44221 tgcaacgaca aaagagacga aagtcgttaa ccgcagccat gtcatataac tgactttagg
    44281 gaacagttta tggaaatctt gtgcaaaaga aacaacgagt cccatagcgg tagtgaagac
    44341 acctaatgtg accatcactc ctaagaagct agcgccgaag ttacctaaat aaaaattagt
    44401 gatctgagaa agtgcagttc cgccattttc tgataaagac atcttattca aactcatcgc
    44461 accgagaaga acaagaccaa aatagatcat gacttctagc gcaacgctca ggctaccagc
    44521 ttttgctgtt aattctgtga cttttttatc tttgaaacca aggtcacgga ctgcatggac
    44581 aaaagtgaca cttaaggcaa gcaaggctac tgcatcaacc gtgttataac cttctaggac
    44641 accatttgtt aaagcgtttg tttggtaagt atctgcagca gattgattta gatttcccat
    44701 tgggtggaat aaagaaacga caaaaatgat tgctaataat gcaagaaaca aggagtttag
    44761 atactttccg acgtatttga ccaaccgtgt gggatggaca gtaaggaaat aagcaagtaa
    44821 aaagaaaaga gcagagaata aaaacatacc taatgaatta tatttttcag gcaaaaatgg
    44881 tttagcagcc atttcaaaag cagtagcagc tgtccgtggt gtaccgaaaa atggtccgat
    44941 cgtcaaatga acaaggatta agaacaaggc agcataccat tttccgacag gtttagctaa
    45001 gtcatacaga ccatcacttt ttgtcactac tacagctaag atagctagta atgggaaaag
    45061 agcgcctgag atggcaaatc ctacgccagc actgacccag tttgcgccag ccatttgacc
    45121 taagtggaca ggaaagatta gattacctga cccgaaaaac atcccgaaga taagtgaact
    45181 gaccatcaat agttgtttcc atgaataagt ttttgtttct tccataaatt tttcctccaa
    45241 taattatcat tttgattgac gatataaacg ttgcagcaat tagtaatgcc actaatatca
    45301 gattccatga aaaccaccac cttaaaatat aaaaaaaagc ccttttccac ttgggaaaag
    45361 ggctctagat tctagaacgg taccaccttt tttcgcttaa aaaagcttct tcattcacgg
    45421 acgctttttg ataaagttat ccgctagcct gataatggag gcagccacaa tgatctacgt
    45481 tttcgacatt gactcggaaa tgatgttcgt ctattcgatt tattgtcatt tctcacttac
    45541 atgactcact gggaataaat cgttgaatag cctactgttt tcctcgacgc tttgctgtat
    45601 gtttatttgt tgacgtaata atacacctgt tttttttgaa atgcaagaat attttaacta
    45661 ttttgttttc tttttttgaa acaagaaaaa tacctagaga atacctctga atgaaacgga
    45721 atattttgtt ctccactttc atataactta cattctcaga ttctttttat caaaacgaga
    45781 cctttagcga atggaaacag ctatttttta acgtttcttg gtacgtatgg ttaaacgact
    45841 cttttacaac cttttcttat ttgctatata gtttcttctg agtatggtaa aataggaaag
    45901 aatgaatcga aaaaaagggg atgtctattt ttgacggaag agtctagttc tttagagatt
    45961 agattgacag ctgctgatga tgtcagcatg cttttaggtg cacacgacaa gcatataaaa
    46021 ctgatcgagg aaacaacgga aacaaccatc catacacgtg gagaaatcat tcagatcatt
    46081 ggtgaacaat cccagatttc cttggctgcc tcagtcattc ggacattaca ggaattgatc
    46141 aaacgaggaa tccacgtaag tacaccagat gtcgtgacgg cattgaaaat ggggcaaaaa
    46201 ggtacattag attattttgt tgagatgtat gaggaagaga tcgtcaaaga ccgtaatgga
    46261 aaacctatac gggtaaaaaa cagcggtcaa aagaaatacg ttgaatcggt agccaaacat
    46321 gacatcgtat ttggtgtagg gccagccgga acagggaaaa cgtttcttgc cgtagtatta
    46381 gcaattgctg ccctaaaaaa aggcgaagtg caaaaaatca ttttgacgcg gcccgctgta
    46441 gaggcagggg aaaacctagg ctttctaccc ggggatctga aagaaaaagt ggatccttat
    46501 ctgcggcctg tttatgatgc tttataccaa atttttggat tggatcatac gaaccgattg
    46561 atggaacgag gcgtaatcga aatcgcacca ttagcttaca tgcgggggcg gacattggat
    46621 gatgcattcg ttatcttgga cgaagcacaa aacacgacag tcgctcagat gaaaatgttc
    46681 ttgacccgtc tcggttatca atcaaaaatg attgtcaatg gggatacaag tcagatagac
    46741 ttgcctcgag ggacgacaag tggtcttgtt catgcagaac gaacactaaa gcaaatcaaa
    46801 aaaatcgatt ttgttaattt tgaagcaagt gacgttgttc ggcaccctgt agttgccgaa
    46861 atcatcaaag cttatgaaaa ggcggatctt catcaagaat aagctttgct taggaggata
    46921 agcacatgtt gaataaaaca ctgcagaaac tacaagaaaa actcggaaag gcagcattgc
    46981 ctttccttct gttcttgttt tttatcattg tctgcggcgt tacatttagt agtgtcaaac
    47041 aaaaggccaa tgatttcaga gaaggccaag tagcagaaga gagtatccgt gcgaataaaa
    47101 cgatcgagaa cacggaagaa accgaacaaa gaagaaaact ggcagcagaa gcagtgactc
    47161 cagaatatac ttatcaaaaa gatctggcag atgaccagaa caatcggatc aagcaattat
    47221 tcgaattgat cgataagacg aatgatacca tcaacaaatc ttataatgac aaggtagata
    47281 aggcgaagga agatgaaaat atcccgaaac ctactacaga agagcggatt gctacactga
    47341 agaaaaattt tgaaaacgtg aatgcagaaa acgttgcgtt ttaccaaaaa ctgccgaaca
    47401 atttttattc gacgatattt gaaatgactg aaacggaaat tcacacggtt agggatgaaa
    47461 gtttgaagct cattgacgaa cagatgagta aacaagttcg tgaaagcgaa ttggaagctt
    47521 ttaaacaaga agcagaagat cagattcagt atttgaatgt cacaacagag cagcaacaaa
    47581 tgattcgcta cttagtggat caaggcattg tagtcaatga tgtattgaat gagaaaaaga
    47641 cagaagaatt aaaacaatct gcacgagaag ctgtacaacc agtgatgatc ttccaaggag
    47701 aaatcattgt tcgcgaagga aatcaaattg atgcttcagc gatgaaaaaa ttggaattac
    47761 taggattgac gaatcaaacg acttcgattt tcccactcat tgccatggtt ttagctgttt
    47821 tgcttcaaat cggcgtactg atttataatt cacttcaatt ccaaaatgca ggagaaagaa
    47881 caaaatacgt gcttttctat gtgacagcta tgtcagtcag catagtgctg atgaaatttt
    47941 tccaattatt ccaaacggaa caagctactt atatcccgct gttttatccc gctgcttttg
    48001 caccacttgt tttaagcttt ttcttgaacc gaagagcagg gatcatggct ggtattttcc
    48061 aagcagtatc tgcacttttc attttttatg attcgattgg cacgaacttt ctaacgatta
    48121 tcttgatgtc ttatgttttc tctgggctca tggcaacgat tgtcagacgc aaacggatct
    48181 cagaacaagg attatctgct gccatgtggg tcattatttt tcctgtgatg atggatgtca
    48241 ttttgatcgt ctatcaagga atgagctttg gtgatgcaac gacttggtta atgcttgtct
    48301 gcgggttcac tggtgcactc ttctcattct tgctgacgat cggtctacac ccatatattg
    48361 aattgatggt caatgatgac agtgtaattg tattaaatga actcagcaat ccaaatcatc
    48421 ctttattgaa acagttgctg gaagaagcgc caggtactta tcatcatagt atgatggtag
    48481 ctaatctaag tgctaacgct gtagcagaaa tcggcggacg ttctttgcta actcgagtag
    48541 cttgctatta tcatgatatc ggcaagatca aacatgctag ctttttcgtt gagaacttgc
    48601 cttcaggagc ggaaaacccg cacaatttct tattgccaga agacagtaaa catattatct
    48661 ttggacatgt gacagatgga gccaaaatat tggaagatta taatatgccg caaatggtga
    48721 tcgatatttg caaacagcat catggaacca cgctaatgcg ttatttctac atcaaagcga
    48781 aagaacgcaa tccggaagta acagaagagc aattccgtta tcctggacca aaaccgcaaa
    48841 gtcgtgaagc agggatcgtc aatattgctg acagttgtga ggctgcagta cgggcaatgg
    48901 atcatccgac gagcgaaaaa atcgaaagtt ttgtccataa tcttatcgaa gagcgtattt
    48961 ccgatggtca attagacgat agtggactga ccttgaaaga aatccgaaaa gtggaaaaat
    49021 cattgatcag cggtttaagt agcaccttcc attctcggat caaatatcct aaaatgaaaa
    49081 cagaagttga gaagataaag gaagaacaag aagaatagaa agaagcgatg tataatggat
    49141 attaccttta tggatgaaac aaaccaagtc tcagaagaga aaatgaaaga aatcgatgac
    49201 ttgctgcaat ttgcagcatc ttatttaaag ctgccagagg aaacagaaat gtctgttact
    49261 ttcatggaca atgcggcaat ccaagtaatc aatcgtgatt accgtggaaa agatgcaccg
    49321 acagacgtca tcagttttgc tctggaagaa gaaggcgaag acgaaatccc agtgattttt
    49381 gaagatggag agaatccttt gcctcgtgta ctaggagaca tcatgatttc tattgaacgt
    49441 gctgctgaac aagcagaagc ttacggccat tcatatgatc gggaacttgg ctttttagcg
    49501 gtacatggat tcttgcatat caacgggtat gaccatatga caccagaaga tgagaaagaa
    49561 atgtttggtt tacagaaaga gatcttggat gcctatggac tcaaaagata aaaacgtaga
    49621 gaaaaacaaa catttcctga tgtctgtgga atttgctgtc caaggagtca aaaccgtttt
    49681 tgaggaagaa cgcaatatga ggaaacatgt tgcgttcggt atccttgctt tatttatggg
    49741 cgtgattttc cagcttgatc ggatagagtg gttatggctg cttttagctg tttttctcgt
    49801 ttggatagta gagatcatca atactgtttt tgaaaatgta gtggacatgt ttacggattt
    49861 tcattttcat ccgattggga aaaaaatcaa agatatggca gctggagcag ttttagtgac
    49921 cgcttgtttt gctgtcatca ttgggttgat tttatttgtc cctaaaatat atcatttgtt
    49981 gtttaattaa aaaggagaac gtatatgcca gaacataaat cagggtttgt cgcaatcgtc
    50041 ggccgcccga atgtaggaaa atccacatta ttgaaccgaa tcgtgggtca aaaaattgcc
    50101 attatgagtg acaaggcaca gacaactaga aataaaatcc aaggagtata tactacacca
    50161 gaagctcagc tgatttttat cgatacacca ggaatccata aaccaaagca tcgtctagga
    50221 gattttatgg tagaagcagc ttacagtgcg ttgaaagaag tggatgcagt cttatttatg
    50281 atcagtgctg atcaaaaacg cggccgggga gacgatttta ttattgaacg tctaaaaaac
    50341 gtgcattctc cagtttatct gattatcaat aaaatcgata agatccatcc agacgagttg
    50401 ctgggaatca tcgaagatta ttcgacgcag atgccttttg cacaagtgat tccgatctct
    50461 gctacagaag gaaacaatgt cgaacgctta atggatgtat tagtcagtga aatgccagag
    50521 ggcccacaat attttccaga tgatcaagtg actgatcatc ctgaatactt tatcgtttct
    50581 gaattgatcc gtgagaaagt cttgttttta acacgagacg aagtgcctca ttctgtcgca
    50641 gtcgttgttg attcgatgaa gcgaaacgag aatgataaaa tccatatcca ggccacgatc
    50701 atcgtcgaaa gagatagcca aaaaggaatc attatcggca aaggcggaaa aatgctgaag
    50761 caagtaggaa cgaaagcaag aaaggatatc gaaaatcttt taggagacaa agtatttcta
    50821 gaactttggg tcaaagtcca aaaagactgg cgagacaaaa aagtctatct gcaagacttt
    50881 ggctaccgaa aagacgaata ctgatattct gaacttctta taggttaagt atagaaataa
    50941 actggataaa aatccgcacg ttgagaaaaa cggcggaaga tcgaaacata aataatctgg
    51001 atcggcagaa tctgcttttc cagatttatt ttttaggagg gagaatatga gccagcttgc
    51061 agaatcgaaa ggcttgattt tatctagccg taattacaaa gaaaaagata aattagtcaa
    51121 aatctttacg gaatcttctg gcaaaatgat gttttatatc aaaggaatcc atcggcaaaa
    51181 tcagccatta gctccggctt tgctcccctt taccgaagca gtctatatcg gtaattttcg
    51241 aagtgaaggt ttgtcgtttt taagcagtgt caaagacgtc catgcgtttc ggaacatcca
    51301 agaagatatc tttttgagcg gttatggtac ctatttgcta aatctagtag atgcagcaat
    51361 cgaagatcat caatatgacc cgcatttatt ccaatttacg caacaagctc tgcagcggat
    51421 ggatcaagga gatgatgcag aaatcatcac gaatatcttt gaagttcaaa tactgcaacg
    51481 cttcggaatc gcgccaattt ggacgcactg tgtcgtatgc ggggaaacaa aaggaaaatt
    51541 tgactattct tccaaatctg gcggtgtgat atgcgagaaa cactggccaa tggacgaaca
    51601 ccgttatcat gcagatcctc gcgctgttta tttcgttcga atgttttcgg ctatttctta
    51661 tgataagatc agtggaatcc acttgaaaga agaaacgaag caggcaatcc gtgacctcat
    51721 tgaccagttg tatgatgaat atgtcggtat tcatctaaaa agcaaaaagt tcattgatca
    51781 aatgaagtct tgggcacacg tattaaagac gccagagaaa aatatgcctg aaaaagagat
    51841 acctgaaaaa gaagaataaa tgaaagatac aacaaaaaaa tcaaaactat ttgacaaata
    51901 cagggacttc cgtctattat taaccgtaga ttaaatagat cgttcactga gaggatctat
    51961 tatataaaca agaaaactgc aaaatgaata cgtacattga ccaagatcag taaaaaacac
    52021 gtggtttagc gagttcggga gagtggaagc cggacccaaa cgatttttga agaggcactt
    52081 gcgagtacga taaatgaagc tgccgaatct ttattcggaa gtagggtgga accgcgaaat
    52141 tattcgtccc tatgtctgta atcagacata gggacttttt gtcgttttct ttcctgtatt
    52201 cttattgaca gcaacgctta aaaattgaaa ggggcaaaac agatgagtaa aaaattgacc
    52261 gtccaagata tgattttaac attacaaaaa ttttggtcat caaacggctg catgctgatg
    52321 caagcttatg acacagaaaa aggagcaggt acgatgagcc catatacatt cttacgggca
    52381 atcggaccgg aaccatggaa tgctgcttat gtagagccat cccgccgacc agctgacggg
    52441 cgttatggag aaaacccaaa ccgtttgtat cagcatcatc aatttcaagt cgtaatgaaa
    52501 ccttcacctg aaaatatcca agagctttat ttagaaagct tgcgtctttt aggaattgat
    52561 ccattagaac acgatattcg ttttgttgaa gacaactggg agaacccatc gatggggtgt
    52621 gccggtgtgg gttgggaagt atggcttgat gggatggaga tcacacaatt cacgtacttc
    52681 cagcaagtcg gaggactacc ttgtaaacca gttacttctg agatcactta tggactagaa
    52741 cgtcttgctt catatattca agaagttgaa agtgtctatg atctggaatg ggctgatggt
    52801 gtgaaatatg gcgagatctt caaacaacca gaatatgaac attccaaata ttcttttgaa
    52861 gtaagtgacc aagacttgct actaagcaac tttgaccgtt ttgaaaaaga agctaaacgc
    52921 tgtatcgatg aaaatcttgt tcatccagcg tatgattata ttttgaaatg cagccataca
    52981 ttcaatttat tagatgctcg cggtgcagta tccgtaacag aacgagcagg ttatctttcc
    53041 cgtatccgca acatggctcg tgctgtagcc aaaatctttg tggcagaacg cgaaaaatta
    53101 ggattccctt tattgaataa aaacacagca aatccagaaa acatgaagga ggctgaataa
    53161 gatggcaaaa gacttattac ttgaaatcgg gctggaagaa atgcctgctc atgttgtcac
    53221 accaagcatg aaacaattag aagaaaaaac agcaaaattt ttagatgaaa accaattgac
    53281 ttatgatacg atcgaaacgt tttctacacc gcgccgctta gcaatcaaag taacaaacat
    53341 tccagaacgt caagcagaca gcgaagaaga agtcaaagga ccagccaaaa aaattgcttt
    53401 ggacgcagat ggaaactgga cgaaagcagc tgaaggattt gtccgcggac aaggtctgac
    53461 gacagatgct atcactttta gagaattaaa aggcgtggaa tatgtctatg taacgaaata
    53521 cactcacggc aaagaagcaa aagaagtatt gacaggttta gcagatgtca ttaaaagcct
    53581 cactttccca gtaacgatgc actgggcaga atacgatttt gaatatattc gccctattca
    53641 ctggatcgtg gcattgttag atgacgaaat aatcccgttt gagatcttgg atgtcaaaac
    53701 agacagagct tcaagaggtc atcgtttctt aggcgaagat gtgacattta cgcatgcaaa
    53761 agaatacgaa gaaaaattga atgaacaatt tgttattgct tcaccgcaaa aaagaaaaga
    53821 aatgatcatc acacaagcaa acgaattagc cgaaaaaaat cactggatca ttgatctaga
    53881 tgaagattta ctagaagaag tcaacaattt agtcgaatat ccaactgtct tttctggcga
    53941 cttcgaagaa aaatatctat ctgttcctga agaagtacta gtcacttcta tgaaagaaca
    54001 tcaacgttat ttcgaagtac ggaacgatca aggtatgttg cttcctcatt ttatttctgc
    54061 tcgtaatggc gatcgggtaa aattggaaaa tgtggtacga ggcaatcaaa aagtattgac
    54121 ggctcgttta gaagatgcgg aattctttta taatgaagac aagaaagctt caatcgacca
    54181 atacgttgaa aaattaaaaa ctgttacttt ccatgaaaaa atcggtagca tctatgagaa
    54241 aatgcaacgg gtacaagtca tcgctcgcat cataggcgaa caagtaggac tatctgagga
    54301 agaattgatg gatctgcaac gcgctgctga aatctataaa tttgatctag taaccaacat
    54361 ggtaggagaa ttccctgaac tacaagggat catgggagaa aaatatgctc tgctgaaagg
    54421 cgagaaacca gccgtagcaa cagcgatccg tgaacattac atgcctatat ccagtgaagg
    54481 agatttacct gagactacag taggttctgt tttagcgatt gctgataaat tagatagtat
    54541 cttttctttc tttgcagttg ggatgatccc aagtggctca aacgatccat atgctttgcg
    54601 ccgtcaagca tatggtgtcg ttcgaatcat cgaatcgaaa aaatgggcct ttcctttgtc
    54661 tgttctgcaa gaaacgatta gtgaagttat cagtaaagat acggatcgtt ttggcattgg
    54721 cttgtcagcg ggacaacaac aggtgatcga ctttatcaaa ggccgtctgc gccaattatt
    54781 gacaacgaag aatatccgtc atgatgtcat cgaagctgtt ttgaatgcag aacaaaaaga
    54841 tctgacaaaa gtatttgcag cagcacaatt gttcaagcag catcttgcag atgaagactt
    54901 caaaccatcg atggaagctt tgacacgtgt cgtgaactta gcgaaaaaag cggagcttga
    54961 aaaacaatca gaagtagacc ctgaactgtt cgaaaacgaa gcggagaaag aactgcacaa
    55021 agcagtagag gcaatgaaaa caagctttgc tgaccaaacg atcaacgaaa attatgatca
    55081 gcttgtaagc cttcgcccac tgatcgaaaa ttattttgat cagacgatgg tcatggcaga
    55141 agaaccagca gtacgtaaga accgattaac gcaattaagt caaattgctg ccatggcttt
    55201 gtcactagca agtttagatc aaatcatcac aaaataattt ctaatatgta aataaaccag
    55261 agaacaggca caaaataggc tatttctctg gtttatttgt tataaatata aataactatt
    55321 attaattcaa tgttaatttt tttgttattt tattttttgt gtaactttta aaaacaccta
    55381 tgaaaattaa ggaaataaaa atgaaatcga ttaattgtta tcttattaat gttttattta
    55441 cttttaaatc gtaaattgcc ctagtcaaga aaatagtttg tggtatgatt atatagggaa
    55501 aacttgttta caaatatttc tgtgaatata ttaatttaat tatgtttttt aaaataaaaa
    55561 gctgtcattt ttatgtatgt gaattatatc ttaatttatc tatcatcaat acttaggagt
    55621 gaatctatgg aaaagccatt cgtcaagtca ttgactgctg tggcggtagg tgcaggtgct
    55681 attgcgatct gtttgtttgg ttaccatatc aataatcagc ggcaacatca gcaacggatc
    55741 aattatgcag aatctgccat caccaatcaa aaagacacct tgacttcttt atcaaaagaa
    55801 gtagacaagc tgtatagtac aaaagaaaaa aattttctaa accctgaaat aacagaagaa
    55861 acaatcacaa gtttgtcaaa taagctatcc tctgtcaaac tttcagcaga tgattacgac
    55921 atcaaagaat cagaattgcc taaagaagct gttgcaatcc aagatgagaa gaaagcaatc
    55981 gtgacacagt tagatagtgc agaatcaaaa ctgaagatcc agacagctgt caacgattta
    56041 tttactaaaa atgtatcaaa ctggcagcaa gctgtagacg atgtcgtcat caaagaaaag
    56101 gtgacaagtg cagatgtcgc tcgtgtacgt gaaaatatga gcttttttaa agatagtcct
    56161 tggaaaacgg ttgttatgca atatctagga ttcgctgata ctcagatcgc gcaagtcacg
    56221 caactagatc agttattcga tacgatgttg aaggatggtc aagtgactgc caccgctact
    56281 tacgatcaat atttgacggc gctcagtcaa atagagcaga tccggaatga aaaaataagc
    56341 gcagcatacg caacaaaagc acaaactgtt gctcagcaaa tgggctatag caatataagt
    56401 tattgacagt taaaacgttg attcaagcaa ggttagcaaa cggaggaaac tatggcaaga
    56461 cgaagaagaa aatcaagagg gaaaaaaata tttctgatta ttttagcagt tcttatcgta
    56521 ttagtattag caattgtagg agtaggagca aaattatatc tggatctctc acattctatt
    56581 gagaaaactt acgaatcagt ggaacgaacc caaggagaac gaacgaaacc agttgatctg
    56641 gacaaacaag aatctttctc tgttctattg atgggcattg atactggaga tttaggtcgg
    56701 gtcgatcaag gaagatcaga tacgatgatg gttgccacag tcagtcctga agacaaacag
    56761 acaacgatcg tcagcattcc tcgagatacg tatgtcgaca tcgtaggtcg tgacacaaaa
    56821 gacaagatca accacgctta cgcattcggc ggagctgcca tggcgatgga taccctacaa
    56881 aaatatgtag acatcccaat cgatcactat gtctctatca atatgaaagg gctaaaggaa
    56941 ctcgttgatg cagttggtgg tatcgaagtc aataatgacc tcactttctc acaagatggc
    57001 tatgactttc caatcggtaa aattacattg aacggggatc aggcattatc ttattctcgt
    57061 atgcgttatg aagatccaaa tggtgactat ggtagacaag agcgtcaaag aaagatcgta
    57121 gaaggtgtag caaaaaaagt attgagttta aacggtgtca gcaactatca atccgttttg
    57181 aatgctctag agtcgaatat gaaaacagac atgagctttg atgaaatgaa aaaaatcgct
    57241 ttagattatc gggaggcatt tggtacgatc aagcaagatc agctgcaagg agaaggcttc
    57301 atgcaagata atatctccta tcaaaaagtc agcgatcaag aacttgatcg tgtgaaaaaa
    57361 gaattaaaag atcaaatgaa tctagagaat aaataggaaa gtggagaaaa aatggaagag
    57421 acaatcagct tgaaagaaat ttttgaaaca ttacgcaaac acttggtaac aatcatcatc
    57481 tcaatgtttg ctggcttggc catctcagga atcgtaacat ttttcatctt gacaccaaaa
    57541 tacagttcac aagcacaatt gatcgtgaca ctgccacaat cagacacagc aaatgtcaat
    57601 gatgtcaata cgaacctgca aatgatcaat acgtataaag atatgatcgt cagtgattta
    57661 gtactaaatg aagtcaaaga tcgtttagaa acagaagaca atgtgaaaat gactgctgga
    57721 caaatcaaag atgcgatctc cgtcaatcag tcacaaaatt cacaaatgtt ctcgatccag
    57781 gcaataagca cgaatgcagt gactgctcaa cagatcgcta acacaacttc acaagttttc
    57841 caagagaacg caaaagacgt gatgaatgtc gataaaatct cgattatttc aggtgcagtt
    57901 gccaatacga cacctgtttc gccaaataat aaattgaatc tagtgattgg cttagtatta
    57961 ggaatgatgg taggcgtagg tctggcattc ttattcgaat tacttgatcg gacagtgaaa
    58021 gatgaaaaat atgtgacgga tgcattagga ttcccaatct taggaacagt tccagaaatg
    58081 tcagcgaaag aattgaacgc tggtatccgt aaaaaaggaa cagctcctgc acgaccaaaa
    58141 gctacaaacg ataaaacagc cccatcacgc agaagccgct caagagtcta ggaggaagaa
    58201 aaatggcacg aacacagaaa caaaaagcag cacaaactca tgcagtcagt ttgatcacat
    58261 taacaaaccc atcttcacca atcgccgaac aatatcgtac gatccggacg aatatccagt
    58321 ttgcctccgc agctggtcag caaatcaaaa cgattgtcgt gacttcatca ggtcctggag
    58381 aaggaaaatc caccactgca gcaaacattg cagtcgtttt tgctaaatcc ggtcaacgag
    58441 ttctactagt cgatgcagat ttacgtaaac ccgtcgtcta taagacattc cagctgaaca
    58501 atgccagggg attaagtaca gcacttagtt catcaggaag tgtagcagat gtaatccaac
    58561 gaacgccagt cgagaacttg tcgattttgc ctagtggacc taagccaccc aacccatcag
    58621 aattgttaag ttcgccaaga atggatcaga tcctagacga agcaagacag ttatttgacg
    58681 tggtgatatt cgatatgcca ccagtagtag ccgtaacaga tgcacagatc atgtcttcaa
    58741 aaacggatgg cactttattg gtcgtacgtg aaaatacatc acgtaaagaa tcattgaata
    58801 aagcaaaaga actgctagag atggtacaag cacgagtttt aggtgttgta tacaacggag
    58861 cagaacatag caaagatgct ggttattact acggaaatta aggaataaga agagaggaga
    58921 caagagaaat gatcgatcta cattgccata tcctaccagg aatcgatgac ggggcagaaa
    58981 acttagaagc aagtattgca atggctgaaa aagcgattca gcaaggcatc acgcatattt
    59041 tatgcacacc acaccacaat aatggaaaat acagcaatga aaaatcacaa gtcatttctc
    59101 tagtcgcttc gttacaagcc gaattagaga aaagacagtt gcctttgacg ttattggaag
    59161 gacaagaagt acgtattacc ggaacgctca tcgaagacat ccaccgagat gaaattttat
    59221 ttacagattt agatgataca tatcttctga tcgaatttcc gacactggaa gtgccgttat
    59281 atgcagaacg gctttttttt gagttgttag aactaggaaa gacaccagtg atcgtccatc
    59341 cagaacgcaa cgcgcatttt cgcgaagacc cgaatcattt gcttccgttc ctagatatgg
    59401 ggtgtttggc ccaacttact gcgccaagtt atgttggggt atttggcaaa gatattcaga
    59461 aaacagctaa aacaatggtc aaacataatc tcgtgcagat gactgcttct gatgcacacg
    59521 gagtctctaa gcgcaccttt tacttaaaag agtgctatga gcagattgcc aaggactttg
    59581 gtaaggaaaa agtagtacag atgaagcaag ttgcaaagga tctgatcaac ggggatgaaa
    59641 tcagttatcc agactatgaa gaggtaaaaa agaagaagtt tggtttattt tagggggaat
    59701 taaaaagtgt ttatattaac aagaagaaga aaaattgcca cattggtttt tgtggacagc
    59761 ttgttattaa ttgctgcaaa tattgcagca gctaaattca tgaagccgtt tgtatctata
    59821 ccaatggatc ttattttaat ctctatcggt ttgtcgattg gtttttattt attttatggt
    59881 agtttattca aagttttcac tcggatcaat cgctatacaa atttaagaga gatcattgca
    59941 atttttagtt cactatctgc aagtgctgcc tcaagtatcc tcatactgct gttcattaat
    60001 cggcgataca gtttacggtt agttatcttt gcttatctgc tttcgctctt attgatcatc
    60061 ggtagccgat tgatctggcg tatctacatc gaaacaaaaa atatgagata cgtatcagca
    60121 gattctgcta aaaatacatt gattgttggt gctggcgaag gcgggcgtat tttatacaac
    60181 agctttcttg gatccaaaac ggctcaagat atccacgttg tcgggtttgt agatgatgat
    60241 ccaaataaaa gaaatacgta tctttcagga aaaaaagtat taggtgcatt aaaagatatt
    60301 ccggaattga ttgaaaaata tgacattcaa atggtaacga tcgctatccc ttccttatca
    60361 agaaaaaaat tacgacgaat cttcgagtta gtcgaatccg ctcgtgtgaa agtcaacacg
    60421 atgccttcta tagaagaact tgcttcaggg aaaattagcg tatcaaaatt aaaaacaatt
    60481 gacgtagtgg atttactggg aagagatgag gtaaagctgg atattgaatc catcaaagat
    60541 cagatcacag acaaagtcat tcttgtcacc ggcgcaggag gatcgatcgg ttcagaaatc
    60601 tgtcggcaaa tcattcaatt caatcctgca aagctattgc ttttaggaca tggggagaac
    60661 tcgatctact tgattgaccg tgagttacgc acgcatcatc aaaattgtcc tacagaaatc
    60721 gtaccgatca tcgcagatat ccaagatcgc gagaaaatca atgagatcat ggaacaatat
    60781 catccagata tcgtctacca tgcagctgct cataaacatg taccactgat ggaatataat
    60841 ccaaaagaag cagtcaaaaa caatattttc ggtacaaaaa atgtagcaga agcagctaaa
    60901 gcagcaaaag tgaaaaactt cgtcatggta tcgacagata aagctaacaa tcctccaaat
    60961 gtcatgggtt caacaaaacg aatcgctgaa atgattgtga ctggattgaa tgaagaaggc
    61021 tgtacgaaat tctcagctgt cagatttggg aatgtccttg gttctcgcgg tagtgtgatt
    61081 ccagtattca gagaacaaat tgctcaaggt ggtccaatca ctgtaacaga ctttcgtatg
    61141 actcgatact ttatgacgat tcctgaagct agtcgtttag ttattcaatc tggcgcatta
    61201 gcaaaaggtg gcgaaatttt tattctagat atgagtgaac cagtgaagat tgtagaccta
    61261 gcgaaaaaca tgatccgatt gagcgggtat agcgaagacg aaatcgaaat cattgaaaca
    61321 ggtatccgtc caggggaaaa actatatgaa gaactattgt tggataagga aagaaatgat
    61381 gaagcagttt atgagaaaat ctttgtagga aacatcaaag gttactcaat acaaaaagtg
    61441 atggattttg tcaagagcct gccgcaagac gatgaacaat tggctaaaga cattgtcact
    61501 tttgcaaatg cttcgaatag ataggagatt aaaaattgaa tattttaata ttaagttgtg
    61561 gacgtcgttg tgaactagtg aatgcattta aaacagcatt aaacaataat gaaatggaag
    61621 gaaaaatcat tggagcagat tgctctgaac tagcacccgc actatatatg tgtgacgaaa
    61681 aaatagtatt acctaaagtt tcagaaagta attatattga ggaattaata aaagtaataa
    61741 agttttttga aattaaatta attgttccta ctattgatac tgaattatca acattatcaa
    61801 gaaataaaaa atatattgaa aatgaaacag actcagttgt attagtttct tcagaaaaag
    61861 tcatcgacat ttgtgagaac aaaattttaa cttctgcttt ttttgaacaa aatggtttta
    61921 aaactcctga aattttaaac tcttctgaaa ttacaaaatt tcctgtattt ataaaacctc
    61981 tgaatggtag ttcatctgtt aacacattta ttgtaaataa tgaaaaagaa ttgttgtttt
    62041 ttagtgaata tatagataat cctcttattc aagagtatat tttaggtgaa gaatatacta
    62101 tagatgtttg cttaaacttt gattcgacac cagtaagtat tgttcctaga aaaagaatag
    62161 caactagagg tggggaaata ctgaagggtc agattattaa agatagagaa ctaattgaga
    62221 ctacgaaaaa gatgttggaa aaattaaatg caatcggaca tattactatt caatgtataa
    62281 aaaacgaaaa gggaatattt tatttagaaa taaatgcaag atacggtgga ggagccccca
    62341 ttagcattaa atcaggagct aattcccctg aatatattat aaagatgata gattcaaaaa
    62401 aaaatttgag atacagagaa aattatttag ataaaatgat agcactgaga tatgatcaag
    62461 cgatttattt agatgaaaaa ggaaatgtat ataatgatta aagcggtgat ctttgattta
    62521 gatgacactc ttgtgtctga atatgattat gtaaaaagtg gatacaaatg tgtagctaga
    62581 agattagcag tgcaaaaaat tttcccggct acttttgacg aaatatatag agtcctttta
    62641 gatctttttg ctgaagatag taaaaatgta tttaatcgtc tatatgacta ttttgaaatt
    62701 ccttatagta aaaaagaaat taaagaactg gtaaatgtat atcgagaaca caaaccagac
    62761 ataaattttt tagaaaatgc agatacttta ttaacggaat taagaagtag aggatacaag
    62821 ctggggatta ttacagatgg gtatgctata acccaacgaa acaaattgga tgctttgaaa
    62881 gtagactatt tggtagatta tatttgtatt actgacgaat taggccgtga attgtggaaa
    62941 ccacacccta tctcatatct tttattgtta gaaaagttta atttaaaggc acaagagtgt
    63001 atatatattg gcgataatga gttgaaagat tttataactg ccaaatcaat aggaatgcaa
    63061 acaattaaaa tagaaagagt aaatggtatt tacagagaaa gcagtttgaa gttcaaaaga
    63121 ttttaccaag ctgataaaaa aatacgttcg ttatgggaga taaaaaattt tttgggagtg
    63181 atttcatgaa aagtaaaaga attctattag cttctccaca tatgagtgaa gaaggatatg
    63241 aaaaagagta tgtaaaagaa gcatttgata caaattgggt tgctccttta ggtgcgaatg
    63301 tgaatggatt tgagaaagaa ttagcagaat acgtgggagc tagtcatgct gccgcattat
    63361 cttctggaac agcagctata catttagctt tgaaagcggc tggggtcggt aaagatgaca
    63421 tagtgatttg tcagtccttg acgttctcag ctactgctaa tccaattctc tatcaaggag
    63481 ctatacctgt atttgttgat agtgattacg aaacttggaa tatgaaacct gaacatttgc
    63541 gaacagcact agaaaaatat cctaacacaa aggctgtatt agtagtacat ttgtacggtt
    63601 tatcagctaa tttagacgaa attactaaaa tatgcaaaga atacgatgtt actctaattg
    63661 aagatgctgc agaatcatta ggaacaacat ataaaggaaa atatactggt acatttggcg
    63721 actatggaat ttattctttt aatggaaata agataatcac aacttcaggt ggcggaatgc
    63781 ttgtatccaa tgacaaagaa aaggtggaaa aagtgagatt ttgggctacg caatctcgtg
    63841 agaaggcacg ccattatcaa cacaatgaaa ttggctataa ttatcgaatg agcaatatcg
    63901 ttgctggtat cggtcgagga caattgaaag tattaaatga aagaattgag aaaaaacgat
    63961 atattcatag tttttataaa aaagaattgt ctaaattgtc aaatatacaa ttcatgccag
    64021 aaaataattg gaatgaaccg aattattggt taagtgtcat aacaataaag ggaataaatg
    64081 cgaatcatct tattgatgag ttagacaaaa ataatataga agcccgccca gtatggaaac
    64141 ctatgcattt acaacctgtt tttaaaaatt atgattatat tggcgatgat gtagcagaaa
    64201 ctttatttga cttaggagta tgtttaccat cagatacaaa gatgacagat gaagatttaa
    64261 aatatgtagt atctacgatt aaaagagtga tcaatgatgc gtaaaaaaac tttctatcag
    64321 ctttttggga aaagaatttt agatatccta ttgtcaggaa ttgctctcat cgttttatcg
    64381 ccgataatct taattgtagg ttttttagta agaattaaac ttggttctcc aattatcttc
    64441 aaacaagaac gaccaggaaa aagtgaaaaa attttttcca tgtataaatt tcgtacaatg
    64501 actgacgaaa gagaccacaa tggagaatat ttacctgatg aaattcgact aactaaattt
    64561 gggaaaatgc ttagagcaac aagtctggat gagctacccg aactttggaa tattttgaaa
    64621 ggtgatatgt cgatcgtagg acctcgtcca ttattagtgg agtatttgcc actatatagt
    64681 gagaagcaac ggaaaagaca caacgtaaga ccaggattaa ctggactggc tcaggtcaat
    64741 ggaagaaatg ctattagttg ggaagaaaag tttgatttag atgtttatta tgttgataaa
    64801 attagtttct ttaatgatct tattattata attcagacat gtaaaaaagt aatcaagaaa
    64861 gagaatatta atacaatcaa taacaatatc ccagaaaaat ttaaagggag ttaaatacag
    64921 cagcttaatg caagttttgt gacttgcatt atatttaggt ataaatcaaa gcgagtatat
    64981 tagaattata taacatatgt taaaaaaacg tatagctaat aaaagtatga ttttaaaaat
    65041 ttgtgtagag ttttaaatat actgtttcaa tacgagaaaa ttataaaaaa gtataaggaa
    65101 aagagagtta tggcaaagta ttataataaa aaaattctta taatggcaaa caacgatgat
    65161 ggtctttacc gttttcgagg aatgctcata aaaaacttag tagatcaagg taatgaagtt
    65221 attgtatctc ttccaaaggg caagaatatt cctaaattaa ttgaacttgg atgtcaaatt
    65281 attgaaactc caatagatag aagaggaatt aatccaaaaa ctgactttaa actatttttt
    65341 aactattgta atattttgaa aaaaataaag ccagatatgg tcattgctta tactatcaaa
    65401 ccaaatatat acggtggatt ggcatgtcgg ttaagaaagg tttcttatgc attaaatata
    65461 accggattag gaacggcatt tcaaaaaaag ggggttttga aaagtcttat tgtatttttg
    65521 tatagattag cagctaaaaa atctaaggtc atatttttcg aaaattttga aaatatgaaa
    65581 acatttcaga ctttacaaat tgctaaacaa agtaaataca agctattaaa cggtgcagga
    65641 gtagatgtag aacactttag ttatttagaa tatcctaaag atgagcaagt tcatttttta
    65701 tttattggaa gaattatgaa agagaaaggt gtagatgaac tttttgaagc aatgaaaaac
    65761 ttatatagtg aagagaaaaa ttgtgtactt gatgtccttg ggtattttga agaagattac
    65821 ggcataaaaa ttgaaaaata cgaaaaagag ggatggttaa aatatcatgg atatcaatct
    65881 gatattcgtc cctttgtaga aagagcacat tgctttgttt tgcctagttg gcacgaagga
    65941 atggcaaata ctaaccttga atcagcagca tcagggagac caattattac aagtgatatc
    66001 ccagggtgta aagaagcagt tattgaatcg aagtctggtt atttatgtga aagaaaaaat
    66061 agttgtagtc tctataattc gatgaataaa tttctaaaat tatcatatga gcagcgcatt
    66121 aacatgggaa aaatggggag aaattatatg attaaaaaat ttaataagaa gaaagttgtc
    66181 gatgaaacaa ttaaatcatt attta
//
LOCUS       DACCVH010000006        65936 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.006, whole genome shotgun sequence.
ACCESSION   DACCVH010000006 DACCVH010000000
VERSION     DACCVH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.006"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            621..1484
                     /locus_tag="IVV98_000443"
     CDS             621..1484
                     /locus_tag="IVV98_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7806128.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1613..3235)
                     /locus_tag="IVV98_000444"
     CDS             complement(1613..3235)
                     /locus_tag="IVV98_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806129.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3484..4005
                     /locus_tag="IVV98_000445"
     CDS             3484..4005
                     /locus_tag="IVV98_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806130.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4191..5921)
                     /gene="spxB"
                     /locus_tag="IVV98_000446"
     CDS             complement(4191..5921)
                     /gene="spxB"
                     /locus_tag="IVV98_000446"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP7806131.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            6086..6904
                     /locus_tag="IVV98_000447"
     CDS             6086..6904
                     /locus_tag="IVV98_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP7806132.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(7007..7204)
                     /locus_tag="IVV98_000448"
     CDS             complement(7007..7204)
                     /locus_tag="IVV98_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806133.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7373..7951
                     /locus_tag="IVV98_000449"
     CDS             7373..7951
                     /locus_tag="IVV98_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP7806134.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8996..9499)
                     /locus_tag="IVV98_000450"
     CDS             complement(8996..9499)
                     /locus_tag="IVV98_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP7806135.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9858..10883
                     /locus_tag="IVV98_000451"
     CDS             9858..10883
                     /locus_tag="IVV98_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7806136.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11206..12084
                     /locus_tag="IVV98_000452"
                     /pseudo
     CDS             11206..12084
                     /locus_tag="IVV98_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12560..12676
                     /locus_tag="IVV98_000453"
     CDS             12560..12676
                     /locus_tag="IVV98_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP7806137.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13604..13942
                     /locus_tag="IVV98_000454"
     CDS             13604..13942
                     /locus_tag="IVV98_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806138.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            14036..14266
                     /locus_tag="IVV98_000455"
     CDS             14036..14266
                     /locus_tag="IVV98_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806139.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14666..15037
                     /locus_tag="IVV98_000456"
     CDS             14666..15037
                     /locus_tag="IVV98_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP7806140.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15311..16003)
                     /locus_tag="IVV98_000457"
     CDS             complement(15311..16003)
                     /locus_tag="IVV98_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7806141.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(16006..16791)
                     /locus_tag="IVV98_000458"
     CDS             complement(16006..16791)
                     /locus_tag="IVV98_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7806142.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            17028..18428
                     /gene="lacG"
                     /locus_tag="IVV98_000459"
     CDS             17028..18428
                     /gene="lacG"
                     /locus_tag="IVV98_000459"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP7806143.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18453..18770
                     /locus_tag="IVV98_000460"
     CDS             18453..18770
                     /locus_tag="IVV98_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7806144.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18783..20456
                     /locus_tag="IVV98_000461"
     CDS             18783..20456
                     /locus_tag="IVV98_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7806145.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20470..22101
                     /locus_tag="IVV98_000462"
     CDS             20470..22101
                     /locus_tag="IVV98_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP7806146.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22592..24157)
                     /gene="guaA"
                     /locus_tag="IVV98_000463"
     CDS             complement(22592..24157)
                     /gene="guaA"
                     /locus_tag="IVV98_000463"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP7806147.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24216..25139)
                     /locus_tag="IVV98_000464"
     CDS             complement(24216..25139)
                     /locus_tag="IVV98_000464"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP7806148.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25335..25940
                     /locus_tag="IVV98_000465"
     CDS             25335..25940
                     /locus_tag="IVV98_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7806149.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26248..27264
                     /locus_tag="IVV98_000466"
     CDS             26248..27264
                     /locus_tag="IVV98_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7806150.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27405..28706
                     /locus_tag="IVV98_000467"
     CDS             27405..28706
                     /locus_tag="IVV98_000467"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP7806151.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28752..29414
                     /gene="deoC"
                     /locus_tag="IVV98_000468"
     CDS             28752..29414
                     /gene="deoC"
                     /locus_tag="IVV98_000468"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP7806152.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29435..29833
                     /locus_tag="IVV98_000469"
     CDS             29435..29833
                     /locus_tag="IVV98_000469"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP7806153.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29899..30981
                     /locus_tag="IVV98_000470"
     CDS             29899..30981
                     /locus_tag="IVV98_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7806154.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31193..32755
                     /locus_tag="IVV98_000471"
     CDS             31193..32755
                     /locus_tag="IVV98_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806155.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32748..33881
                     /locus_tag="IVV98_000472"
     CDS             32748..33881
                     /locus_tag="IVV98_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806156.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33881..34837
                     /locus_tag="IVV98_000473"
     CDS             33881..34837
                     /locus_tag="IVV98_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806157.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34936..36102
                     /gene="deoB"
                     /locus_tag="IVV98_000474"
     CDS             34936..36102
                     /gene="deoB"
                     /locus_tag="IVV98_000474"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP7806158.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            36126..36944
                     /locus_tag="IVV98_000475"
     CDS             36126..36944
                     /locus_tag="IVV98_000475"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP7806159.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36961..37668
                     /gene="deoD"
                     /locus_tag="IVV98_000476"
     CDS             36961..37668
                     /gene="deoD"
                     /locus_tag="IVV98_000476"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP7806160.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37966..38652)
                     /gene="gpmA"
                     /locus_tag="IVV98_000477"
     CDS             complement(37966..38652)
                     /gene="gpmA"
                     /locus_tag="IVV98_000477"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP7806161.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38824..39405)
                     /locus_tag="IVV98_000478"
     CDS             complement(38824..39405)
                     /locus_tag="IVV98_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7806162.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39538..40221)
                     /gene="rpiA"
                     /locus_tag="IVV98_000479"
     CDS             complement(39538..40221)
                     /gene="rpiA"
                     /locus_tag="IVV98_000479"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP7806163.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40540..40953
                     /gene="rpsL"
                     /locus_tag="IVV98_000480"
     CDS             40540..40953
                     /gene="rpsL"
                     /locus_tag="IVV98_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP7806164.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            41037..41507
                     /gene="rpsG"
                     /locus_tag="IVV98_000481"
     CDS             41037..41507
                     /gene="rpsG"
                     /locus_tag="IVV98_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP7806165.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41601..43688
                     /gene="fusA"
                     /locus_tag="IVV98_000482"
     CDS             41601..43688
                     /gene="fusA"
                     /locus_tag="IVV98_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP7806166.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43860..45047
                     /gene="tuf"
                     /locus_tag="IVV98_000483"
     CDS             43860..45047
                     /gene="tuf"
                     /locus_tag="IVV98_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP7806167.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45454..45762
                     /gene="rpsJ"
                     /locus_tag="IVV98_000484"
     CDS             45454..45762
                     /gene="rpsJ"
                     /locus_tag="IVV98_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP7806168.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45793..46422
                     /gene="rplC"
                     /locus_tag="IVV98_000485"
     CDS             45793..46422
                     /gene="rplC"
                     /locus_tag="IVV98_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP7806169.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46450..47073
                     /gene="rplD"
                     /locus_tag="IVV98_000486"
     CDS             46450..47073
                     /gene="rplD"
                     /locus_tag="IVV98_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP7806170.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            47073..47363
                     /gene="rplW"
                     /locus_tag="IVV98_000487"
     CDS             47073..47363
                     /gene="rplW"
                     /locus_tag="IVV98_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP7806171.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47402..48235
                     /gene="rplB"
                     /locus_tag="IVV98_000488"
     CDS             47402..48235
                     /gene="rplB"
                     /locus_tag="IVV98_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP7806172.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48278..48556
                     /gene="rpsS"
                     /locus_tag="IVV98_000489"
     CDS             48278..48556
                     /gene="rpsS"
                     /locus_tag="IVV98_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP7806173.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48579..48926
                     /gene="rplV"
                     /locus_tag="IVV98_000490"
     CDS             48579..48926
                     /gene="rplV"
                     /locus_tag="IVV98_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP7806174.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48940..49596
                     /gene="rpsC"
                     /locus_tag="IVV98_000491"
     CDS             48940..49596
                     /gene="rpsC"
                     /locus_tag="IVV98_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP7806175.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49599..50033
                     /gene="rplP"
                     /locus_tag="IVV98_000492"
     CDS             49599..50033
                     /gene="rplP"
                     /locus_tag="IVV98_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP7806176.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            50023..50211
                     /gene="rpmC"
                     /locus_tag="IVV98_000493"
     CDS             50023..50211
                     /gene="rpmC"
                     /locus_tag="IVV98_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP7806177.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50236..50502
                     /gene="rpsQ"
                     /locus_tag="IVV98_000494"
     CDS             50236..50502
                     /gene="rpsQ"
                     /locus_tag="IVV98_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP7806178.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50560..50928
                     /gene="rplN"
                     /locus_tag="IVV98_000495"
     CDS             50560..50928
                     /gene="rplN"
                     /locus_tag="IVV98_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP7806179.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50965..51273
                     /gene="rplX"
                     /locus_tag="IVV98_000496"
     CDS             50965..51273
                     /gene="rplX"
                     /locus_tag="IVV98_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP7806180.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51301..51840
                     /gene="rplE"
                     /locus_tag="IVV98_000497"
     CDS             51301..51840
                     /gene="rplE"
                     /locus_tag="IVV98_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP7806181.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51859..52044
                     /locus_tag="IVV98_000498"
     CDS             51859..52044
                     /locus_tag="IVV98_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP7806182.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            52080..52478
                     /gene="rpsH"
                     /locus_tag="IVV98_000499"
     CDS             52080..52478
                     /gene="rpsH"
                     /locus_tag="IVV98_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP7806183.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52510..53046
                     /gene="rplF"
                     /locus_tag="IVV98_000500"
     CDS             52510..53046
                     /gene="rplF"
                     /locus_tag="IVV98_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP7806184.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53207..53563
                     /gene="rplR"
                     /locus_tag="IVV98_000501"
     CDS             53207..53563
                     /gene="rplR"
                     /locus_tag="IVV98_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP7806185.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53584..54084
                     /gene="rpsE"
                     /locus_tag="IVV98_000502"
     CDS             53584..54084
                     /gene="rpsE"
                     /locus_tag="IVV98_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP7806186.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            54099..54278
                     /gene="rpmD"
                     /locus_tag="IVV98_000503"
     CDS             54099..54278
                     /gene="rpmD"
                     /locus_tag="IVV98_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP7806187.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54322..54762
                     /gene="rplO"
                     /locus_tag="IVV98_000504"
     CDS             54322..54762
                     /gene="rplO"
                     /locus_tag="IVV98_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP7806188.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54762..56057
                     /gene="secY"
                     /locus_tag="IVV98_000505"
     CDS             54762..56057
                     /gene="secY"
                     /locus_tag="IVV98_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP7806189.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            56119..56766
                     /locus_tag="IVV98_000506"
     CDS             56119..56766
                     /locus_tag="IVV98_000506"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP7806190.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56957..57175
                     /gene="infA"
                     /locus_tag="IVV98_000507"
     CDS             56957..57175
                     /gene="infA"
                     /locus_tag="IVV98_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP7806191.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57208..57324
                     /gene="rpmJ"
                     /locus_tag="IVV98_000508"
     CDS             57208..57324
                     /gene="rpmJ"
                     /locus_tag="IVV98_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP7806192.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57342..57707
                     /gene="rpsM"
                     /locus_tag="IVV98_000509"
     CDS             57342..57707
                     /gene="rpsM"
                     /locus_tag="IVV98_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP7806193.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57735..58124
                     /gene="rpsK"
                     /locus_tag="IVV98_000510"
     CDS             57735..58124
                     /gene="rpsK"
                     /locus_tag="IVV98_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP7806194.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58204..59142
                     /locus_tag="IVV98_000511"
     CDS             58204..59142
                     /locus_tag="IVV98_000511"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP7806195.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59170..59550
                     /gene="rplQ"
                     /locus_tag="IVV98_000512"
     CDS             59170..59550
                     /gene="rplQ"
                     /locus_tag="IVV98_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP7806196.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59822..60661
                     /locus_tag="IVV98_000513"
     CDS             59822..60661
                     /locus_tag="IVV98_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7806197.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60637..61506
                     /locus_tag="IVV98_000514"
     CDS             60637..61506
                     /locus_tag="IVV98_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7806198.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61496..62293
                     /locus_tag="IVV98_000515"
     CDS             61496..62293
                     /locus_tag="IVV98_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP7806199.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62496..63242
                     /gene="truA"
                     /locus_tag="IVV98_000516"
     CDS             62496..63242
                     /gene="truA"
                     /locus_tag="IVV98_000516"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP7806200.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63907..64144
                     /locus_tag="IVV98_000517"
                     /pseudo
     CDS             63907..64144
                     /locus_tag="IVV98_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64288..65064)
                     /locus_tag="IVV98_000518"
     CDS             complement(64288..65064)
                     /locus_tag="IVV98_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7806201.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65187..65594
                     /locus_tag="IVV98_000519"
     CDS             65187..65594
                     /locus_tag="IVV98_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP7806202.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20959 a        11760 c        13885 g        19332 t
ORIGIN      
        1 ccgtgtcaca gtcccttttt ccgaacaaac ggtgttcaaa agcttgcatc tacggcacta
       61 agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt actgcttgat
      121 gcagagcagc tttttcacaa cctctccact aaacggtgtt ctcctgccaa ctcctcggtc
      181 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
      241 ggagctaaac ggcaggctca caacctcttg gtaaacggtg ttcaatcagc tgaccctcgg
      301 tattagctca aaaaacggca aaatatgagg aactattttt tccgtttttt tctctaatac
      361 tcaggtcaaa acgctgattt cacaacctct gattcacggt gttccagaag tagcttctac
      421 ggaaataagc cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
      481 tcttgaagct gaccacttct gtcacaacct cttattttga ttagaacttg cgaaaataaa
      541 ccggttaaag tgtgtctagc gcaagagatt tgctataata gacgataagg gtaaaatgta
      601 acgagaaggg gttgaaaaat gtgtatcaaa ttgtaacaga ttcttgttgt gatctgccat
      661 accatgtatt agcaaaagaa aaagttgatt ttttatcaat gaatctccaa ttgaatgatc
      721 aagagttagt agatgacctc ggaaagacat tcaattatga ccgctacatg aatcagctga
      781 aaaatggtgc gatgcctacg acatcacaaa tcaatgttgg ccgatattta gaatttttcc
      841 gttcttatgc ggaaaaacag attcctgttt tatatgtggc tttttccagt ggattaagcg
      901 gctcttacag tagtgcgctt caagcggttg aattgctgaa ggaagaatat gaagaccctg
      961 agatctatgt ttttgataca aaagctgcaa gtattgggga agggctttta gtattggaag
     1021 ctgtaagatt gaaaaaagaa ggtaaaagca tcgaagaaac cctagagtgg ctggaaagta
     1081 attatttgaa agtccattca tgggtaacag tagacgatct gaaatatcta gaacgaggcg
     1141 gtaggatttc caaagcaagt gctactcttg gcagtctatt gagtgtaaag cctattatta
     1201 cggtggataa agaaggaagg ctgacgaatg ttgacaaagt tcgaggaaga aacaagtcga
     1261 tccagacaat cgtcaatgag acggtaaaaa caatcgttgc accacttgat caaatcgttt
     1321 atgtggctta cgctggggat ctagagagcg cggagaaggc aaaacggctt ttggaagagc
     1381 agataaagat gaaagatgtg aagctttatc ccttaggacc aacgatcgcc agtcacacag
     1441 gctatggctg tatcgcgatt ttttcgatgg gaatcagtcg ataaaagcag taactcattc
     1501 tgtaaaaaag cccagaaatt gattgtaaca aaaacagcga ctcttaaaag atagatgagc
     1561 atcctatctc ttagaggtcg ctgttttttt attttttaag ctaaataggc cattatgccc
     1621 ataactcgtt caattgtttt tgaatatctg cattttccaa aaattcatca tatgtcgtat
     1681 cagctcgatc gatcacacct ttatccgaaa cggcaatgat gcggtttgcc aatgtttgga
     1741 taaattgatg gtcatgtgac gcaaataaga ttgagccagt aaatgccatc aagccgtcat
     1801 tcaatgctgt gattgattct aagtctaaat ggttcgttgg atcatctaat acaagtacgt
     1861 tagctttcga aagcatcatt tttgaaagca tgcaacggac tttctctcca ccagataaaa
     1921 cattcactgg tttcaatact tcttcaccag aaaacaacat tcttcctaag aagcttctta
     1981 agaaggtgtt atcatcttct tctttacttg catattgacg caaccagtct aaaatcgtta
     2041 gatcagtatc gaattctttc gttgtatcct ttggtaaata agaattactt gttgtcacac
     2101 cccaacgtac tgttccagta tctggcgtaa tttcacccat gataactttg aatagcgttg
     2161 ttgttgttat atcattttct gcgacgaaag cgaccttgtc ttctttgctc aaattaaaag
     2221 atatatcatc taaaattttc tttccatcaa tcgttacact tacattttct acctgcaata
     2281 agtcgtttcc aatctcacgt tcaggtttga atccaacgaa tggataacgt ctagaagaag
     2341 gttggatatc gtctaaagta attttttcaa gcattttttt acgtgaagtt gcttgttttg
     2401 attttgatgc attcgcacta aagcgggcaa taaattcttg gagttctttg atttgttctt
     2461 cttttttggc atttgcgttt gcttgaagtt tagccgctag ttgactagat tccaaccaaa
     2521 aatcataatt tcctacataa agtttgattt taccaaaatc tagatccgcc atatgtgtac
     2581 atactttgtt caaaaagtga cggtcatggg atacaacgat cacagtattt tcaaaattga
     2641 tcaaaaattc ttccagccaa ttgatcgatt ggatatccag accgtttgtt ggttcgtcta
     2701 gcaaaagaac atcaggttta ccaaatagtg tttgtgctaa taacactttt accttttgtc
     2761 caccagttaa ttcactcatt tgctgatggt gcaattcttc agggatgttc agaccttgca
     2821 gtaaaacagc tgcttctggt tcagcttccc atccattaag ctcagcaaat tctccttcta
     2881 attcagctgc tcgaatacca tcttcgtcag tgaaatcctc tttcatgtaa atcgcatctt
     2941 tttctttcag cacttcatac agacgcttgt gtcccatgat gactgtttca agtacagtat
     3001 agtcttcata gtcgtaatgg ttctgtttca atacggccat ccgttcatct ggtcccatag
     3061 taacggaacc tgtggaaggc tgcagatccc ctgataacac tttaaggaac gttgatttac
     3121 ctgcaccatt tgcaccaatc aagccatagc agtttccggg ggtaaattta atattcacat
     3181 catcaaatag tttgcggtct gaaaagtgca aactcacatc atttacagta atcaattttt
     3241 ttcctcactt ttatcattat tagttttgac aagtcttata gaattatata ggggaaaggt
     3301 aaaagattca aggcaatcga acattctttg tgtttcacgt gaaacagaat gaaaaaaata
     3361 aaaataaaag cggagcgaaa atagctacta taggatttat tagtttgcaa cagcataatt
     3421 tttgacgtta tttataagag ggagtactat aaaactgtaa aagaaatgaa agaaggattg
     3481 aaaatggatg aaaaaagaac catcgactgg ggctcattga ttttgggaat tttatttgta
     3541 cttgtctcat tgttatcatt tcaagaccct gtcggaaatt tagttgcaat tgtagtagtc
     3601 tttgcgattt ttgcctttat taaagggata tttgaactgt ttgtacggaa cagattaaaa
     3661 gagctaacag gatataaagg aaagatgccc ttaataatcg ggatcatcga tattctagtt
     3721 ggcgtctttt tcttattcaa tattggtgca ggagtcgcag cattgccttt tgtttttgca
     3781 gtatggttta ttgctgattc agttttagcg ttatttactg ctgacttggc aagaggagta
     3841 agtgaaggat attattggtt tacgatcatc gtcaatattt taggaatttt attaggaatt
     3901 ttcttattgt ttaatccaat ttcttctgcg ttgacattaa gctttttagt tggattctat
     3961 tttatgttat ttggtatcac acatatcgtc tatgcattta gataagtaaa atcaaacaaa
     4021 taaaaaagcc ggcttccgat tacagtttta ctgttgtaat tggaagccgg cttttttatc
     4081 atggacaaat atgcacgagg tgatttttag gtgtcgagac aaatttatgc aaaaatgtga
     4141 gaagctatat acacaaattt tatcttaata ctcgaagcat agcgcagttg tcacaacctc
     4201 ttttcatata attcattcaa tactggcaaa tcatggactt catatttttc tttgaatgct
     4261 tggatttctt cttcagaata ttttcttgga tctaaatgca gatcttctac tggcaatggg
     4321 cgcttgttat tgatcttcac atcgattact acaggacgat ctgattttgc agctgcatca
     4381 aaggcaaatc gaagttgcga gtattctgtg actgtaaagc tatttgcccc gagcgcttct
     4441 ccaactttac cgaaatctgc atcttctaaa aatacaccaa atttcttttg ttccgtatct
     4501 tcttgttctg cttcgatgaa accaaaagaa tcattcgaaa agacaacatt aataattgga
     4561 agctgatatt tgacttgtgt aatgatatct tgcatgacca tagcaaaccc gccatcacca
     4621 cttaaggtaa atacttgttt ttctgggtag cttagttgtg cggcaattcc tcctggcaca
     4681 ccattaccca tagttgcgaa ccatccagat gtcgtatgtt tttgtttacc gttcatattc
     4741 aataaacgaa tagaatggat agtcgtgtta ccgacatctg tgacgaaaat cgcatcgtct
     4801 tcagcaatac gattgatttc tttatagaca gcctctggac gaatcggttc ttcctctcga
     4861 tcttcaaaag atttcaacca atttacccat ttttctttat tttcttgatt tgctaggtac
     4921 cagctatcag cagggcgagc atcccctaac tcgacaagtc tttgcaaagc tgtgtttgca
     4981 tcaccgagga tcgacaaaga tgtttcatgg cgtcgtccaa attttgacgc atcgatatcg
     5041 atttggataa attcagcagt tggattaaaa aatgcacgtc caaatgggaa gtcgctaccg
     5101 acaaataaga tcagatcggc ttctgccaat gcttcatttc cgggtttagt agcgacacgt
     5161 ccagcaaaac caagaaagtt ttcataatca tcaggaataa ttccttttgc tagaacggaa
     5221 gcgacaacag gaactgaaaa atgttctgag aattctttga tttgcggaaa tccgtttcgc
     5281 gttccttgac caacataaag aactggtttt tttgcttttt caagataagg caaagcagct
     5341 agcaaatctt tttcttctgg taatatcaca cttgttttgt gagtgtgagc ggtggagaaa
     5401 ggttgttcgt caatttcttc aaaaccaaga tcaacaggga tagtcacgat agccacgcct
     5461 ttatgctcat aggcggcttt aatggcttca tctactacat gcggaagact ttgtggtgtc
     5521 atgactgtac gattgtatac gctaacatct gcgaaaatag gattttcatt tagttcctgg
     5581 aaagagttat agttcatgga tgtagaagca acttgtccta agaacgctac tagaggcaca
     5641 tggtccatct gtgcatcata caaaccattg atcaaatgtg tcgcaccagg tcctgcagag
     5701 ccgaagacag cgccgacttt ccccgttaat tttgcatctg cagcggctgc gagtgcgccg
     5761 acttcttcat gacgaacttg aatgtagttg atttcggttt tttcttgata tagcgcatcc
     5821 ataattgaat tgaaagatcc tccgggaatg ccgtaaatat ggtcgatacc ccagctttca
     5881 agaactttta ccattgcgat tcctgcattg atttttgaca tggtgtttca ctcctttagc
     5941 aatgatgata cataaatttt ttgtatctag agtatagaac tttttatcga aaatcccaac
     6001 taattcgtct tttcacaaaa atgtagtcat gtttttggga atatgctaga gtagtacata
     6061 gatagattca agagagggga atggcatggt tgaatggcta ttgagacttg aaccttggca
     6121 gcaagcactt gctgggacag cttttactta ttttatgaca gctcttggtg ccgggttggt
     6181 ttttttcttt aaagaaatca aaaaagaagt gctaaacttg atgttaggat ttgcttctgg
     6241 tgtcatgatt gctgcaagtt tttggtcttt gttagatccg gctattacaa aagcagaaga
     6301 aaatggagat attgcttggc tagttgtaag tattgggttt ggtttaggcg gtgtgttttt
     6361 atatatggca gataaaacac tgccccatat gcattttgga ccacaacatg aagcagaagg
     6421 attgcctacc catttaaaac ggacgatctt gcttgttttt tctattacat tgcataacat
     6481 tcctgaaggt ttagccgtgg gggtagcatt cggtgcagca gcaactgcgg ataatccgac
     6541 agccgctata ttagccgctg tttcggtggc gctaggtatt ggtatccaaa acttcccaga
     6601 aggagcagct gtatcaatcc cgttgcgaca agaaggtctg agtcgtaaaa aggcctttgt
     6661 ttacggacaa gcttctggaa tcgttgaacc aattgctgga gtgattggag cgctactagt
     6721 aacgaaagtg gagctgctgc ttccttatgc acttgctttt gccgcaggag caatgattta
     6781 tgtcgtggtg gaagaattga tccctgaagc acagcagaca ttgtccagca aacgtcattt
     6841 tgcagttttt ggcgtcatga gtggatttat cattatgatg attttggatg tggcattagg
     6901 ataaataaaa aaaatatata tgatatatca aatagggccg cgaacttata tcgcgaccct
     6961 atttttttag taagttatat cataatgaag tgaatggtat catacattaa taatagtttt
     7021 ttctatgtgt atttcctttg atccagcgaa caagccagat gataagtgcg attgggatta
     7081 gaactttgac cgcaaaccat aaaagcccgc ttaggacact gacaaaaaga ctgatgacga
     7141 agctagctgc aattagcact aaaagaacca tgaagatatt taagaacata tttttttgac
     7201 gcatacaaaa ccctcctctt gttcattctt tactatagaa aaagtataac agggattgtt
     7261 taaaaacacc tccaactgaa gactgatttt tacttcatct acttaaatga tcaaacaatt
     7321 gctttttctc tggtttatca tctaaaatag agcggaaaag gaggagaata tcatgcctaa
     7381 aaatcgtctt gaagcattta cagatgctgt aatcgcgatt atcatgacta ttttagtttt
     7441 agaacttcat gaacctaacg gagacacgtg ggaggcgctc gctgcattag gttaccgatt
     7501 ttttatctat attgtcagtt ttatcatttt agcgatttat tggaacaatc atcatcattt
     7561 atttcaagtt gtacataaga taaatggacg ggtcttatgg gcgaacagtt tctttgtttt
     7621 tgcgctttcg ctttttccgt ttgcaacttc atggatcagt gagtacatca atagcctggc
     7681 tccagaaatg acttatggtt ttgttacctt gaccgctaat attgcgtatt atatcttggc
     7741 aaaagaactt gtcaaagcaa ataaaggcca cgagaaagca ttgaaggcga tgttgaataa
     7801 ttacaagaaa tcgtatctat cgattggttt gaatgtgtta ggaattgtct tagggtattt
     7861 agtagcgcca gtagccgtgc tgatcgcaaa catcgtgatt ctagctgctt ggatcatccc
     7921 aagtcgtacc atcgaatcac aatatcggta aaatgatccg tgtttaaaat ttaagagaaa
     7981 aatatagaaa aaataaataa acgatcaaat atccgagtga tactagtatt caaagaggga
     8041 tgcagatgga tcaaaaaaga attcatgtag gactgattac tagttttgtc acgatgctta
     8101 tttatttgga tcaaggtcat ttgacttgga cagtagttgg tgtcgtagga tttttgacat
     8161 tattcacagc aataaaaaaa taaacatctt tatgtaatct gatgttctat ctatttaaga
     8221 aaagcatgtt tacagcagta tgattctgtt gtaaacgtgt ttttatttgt ggaaaattta
     8281 atttttagaa aagtgtatcg aaaaatagat agttagtttt tccacagtgg ataacttcgt
     8341 aagagataaa aataaaaaat tagtcaaaga agggcgtata gatttctttt gataggagat
     8401 atacaacaga aatgaataaa tattaacgtg ttttcaaaca gtataaaacg gtgtggtttt
     8461 tggaataaaa aaataacata tctcatttta cacttttgtt attttatact taaaaaataa
     8521 cgacacagaa aataccgtgt ctcagatttc tctactactt ctaaaaacta ctgttttttt
     8581 cctttgaaat gccttcaaaa agtaggatca ggcagaatat actggcagaa tcaaggagaa
     8641 gggagcctaa ataaggagaa aaaccataga aaatataaag taattactta taaaacaagc
     8701 tttttataga aaaataatat acctgagtag ggtataaatt aagacggaat tcctttctag
     8761 attgagatat tgactaggaa gaatgttaag attttaagcc tttaagctaa aaaaaaaccc
     8821 tttttgttaa ataaggggaa tatagcctgt cagtttcaaa ctgcaagtcg tcctgctgca
     8881 ataatatagt agattagaga tgaaaataga tttttttaaa ccaatgactg aataaaaaga
     8941 ccgtcataga tacacattgg aatgtgtcta ttacggtctt tttttacgaa cgattttatt
     9001 gaagacggac agttcgggtc aaaaataaaa aagctacgat cagaaataag aataaaatgt
     9061 atcccaaaat aatggctaga cggtctaact tatttgtcga tagatgtttg tttagaagtt
     9121 gataggccca taaacctatc agtcctcctg ttgtattagt tatcaaatca gtgatgtccg
     9181 ctacgccaat accgaatagg aattgaatca attctgccaa gaagcttaca aggaaaataa
     9241 tccctaattt tttagaaaaa gaaagtctct tgaaattgac attcaaaagc accccaaaag
     9301 gaaaaaagac aatcaagtta taagtggtct cacgtaatac cgtcgtattt tcaaaagaaa
     9361 aagtagaaaa agggacgaga ttgacattgc tgtaagaata agtgagaaat tgtggaagat
     9421 taaatgatag cttgaataaa atcaaccata atagaaagaa taaataaatc cctaataaaa
     9481 attttgatac ataccgcata gacatctcct ccatttaaaa agtataccat cgaaaaccgc
     9541 tgaaaaatca taaaaaagta tgaagtttaa ggaccaacgt agttatcgta cgaaaattag
     9601 aagctttttt ttgttgggaa tccggtttct ttaacaaagc taagatagcg agttgcttgg
     9661 aaaagttgct atcttttttc tgtcaaaacg actcggaatg ttcgtttttt gttctaattt
     9721 ctccaagttg tttacttttt gatactaagt ttatgaaaaa tcaagaaata gttgttatac
     9781 taggtaatgc tgacaaacgg gattggcatt tcatcttggt tcagcttttt ttccaattac
     9841 taggaaggag ggatagattg ttcaagactt attttcgttt caataaaata caagataatc
     9901 cttttcgtat catgaatctg atgctactta tctttattgt attatggtta ggttacataa
     9961 atcatgattt tttgatttca agtttttcat cattagggat ctttactttt ttctattatc
    10021 aaaacatacc gatgaaatat ttgctgaaac gtatgtttct gatcggttgc ggactgttgg
    10081 ttgctttcgt tttggggatc ttatcgactt atgttttatg gcttgaacca tttgccgtag
    10141 ctttggttgc tttttccagc agattcgtgt tgcgattatt ccatatttct aaaccaggtg
    10201 gcttgttttt tgcgatgctt tctgccatgg gaacgagcat gcagctgcca atcgctcaat
    10261 taccgatcgt ctcactttat ttttttatgg gtgtcgtttt tgccctgatt gcggcagtga
    10321 ttacaaaatt actggattca cggcctgagc agacaattga aaaagcaact ttaaaagaaa
    10381 gatttcacga agagccttta gtgatcattg attctgtttt ctacagcgct gccttatttc
    10441 tttccgttta tgtcagtcac ggcttgaatc tgcataatcc ttattggttg accttgtcat
    10501 gtgcatcgat tttgctagca gaaaacttgg atgcgatgaa gcatcgacaa gtccaatatc
    10561 tgattggatc gatgggtggg ttatgtgtgt cggcattctt gtcatttgtg ccgtttacgc
    10621 agttgcagac catttttctg atcacttttc tatatggaat cgcacaattt ctagttgcta
    10681 gaaattatgc agttgctaat atttttctta atccgatggc gttgatgcta tctacactta
    10741 ttcgtggagc atacttgatt tctttgatcg aatatcgttt tttagggatc gtcataggaa
    10801 gtttcatcgg tttaggtgtt gcgtgggtaa tgacggttgg tttgcaacat tatttaacgg
    10861 ttgttcgtca aaaattagaa tagaaggaca aatatatgtg ccaaaagagg ttatgacaag
    10921 atttttgtca caacctctaa ttcaaggtgt tcaaaagcca gattctcagc attaagtcaa
    10981 attcacacaa aaatgtggaa aggaactttc aaaaaaattt tatatttatt ctatcaaaaa
    11041 attttgttta tgatggtaac tgaataaact ttcctgagat ggtcaatgct ttccttgaaa
    11101 gtcttacaga tattctttct tcatagaaag tttaagtttt atagttagtg tacaataaaa
    11161 gtatgtttat accatatggt gtccggataa tcagtcattt aaacaatgag gttcaaagat
    11221 atgaaaaggg gaaatttgat gaagaaaata agcaatgaaa tccaaattct ggcagaaact
    11281 ttaactcttc ccaaagtcgt tatagagcaa atgattgtac aagcaaaaaa catccttgat
    11341 gaggtgtttg agcaatatag tcatgaacta atggatccta ataaagcaaa ggcgactgca
    11401 aagaaaatag acaaagtcta tgaagaggaa ccttttgcag cattagctat ttatctatat
    11461 gcagcttctc aaagttggaa aaaaatttat caaccattga agattccaag aactatctat
    11521 ttggcaacaa tgaatgcttt tactagattt attcatgaac atttccaagt aacaggaagc
    11581 tatcgctttg accgtggttt ttggatttgg cattacacta gtggcttgat ctttcggatt
    11641 ggtgaattgg agtacgaaat gacatatttt ccgaaagggt acacggatct aagattagaa
    11701 ggaaagcagt gcctttctct tcatattcct tccgatgcag atttatctca gaataagata
    11761 agagatagtt acgaaagtgc cattcgtttt tttgaacttt attttcctga ttaccattac
    11821 caagtgatgt acacagatac ttggttacta tcacccaatc ttactaaata gttgaaaaaa
    11881 gagtcaaaaa tctgtctttt tgcagccgat tatcgattat tatcagttga tgaacaggac
    11941 gatagtggag tcccttggat ctttggacga gtagatgccc aaatacatga ttatccagaa
    12001 agtacgagtt tacagcgaca agcaaaagag caattgcttg caggcgagca cattggctct
    12061 ggcttaggta ttcttacttc ataagtttag tacttcgaaa tagtttaaaa gagcgtgaga
    12121 caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcagaag
    12181 caactccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt
    12241 cttcttattt cttggagtta aacgcttctg tcccagcctc ttttttagtg ttctatcgaa
    12301 cacacagtac gttcaatagg taaactagct ataacaatag atattaaagt taacggacaa
    12361 gagggccttt tttaggtagc taaaacgtaa taatgaaaat ttatttccag agataggagt
    12421 caatcagcta gtctgatcga ctgttttaac aagttgactt tcattttaac ttttgatacc
    12481 atttaaaaca caaatcgtaa ttgtttcgat ttgtgttttt tagcatgact acaatcaaag
    12541 aagaaagtgg gtcgtccata tggaaaaaac agatatctca agtgcatacc gccgcttgaa
    12601 aagcccaaat atcaaaacac gaaaacgtgc gctgaagatc atcaaagatg tgaaacggaa
    12661 tagtgggaaa aggtaagaag aaggaaactt aattaaaaaa atagccgaaa aacgtttttc
    12721 ggctattttc aataatcggt ttttgtgtaa ggtttccgaa agaactgctg ttgattttcc
    12781 atttttaaca tatgataaat tggtagaatc tttcttttca aattgatacc attccctaat
    12841 tccagttata tagttaacta cagaaccaca aagcacgtac gtttataaaa gtattatctg
    12901 tagttatttt tcaattccct ttcaacctct tattttgacc agtagtattg atcactttac
    12961 cttttaacac ctttgttcgt ttttgaaaca tttttagtca agaatggaaa cgtaactaca
    13021 taatcaaagg ttttgcgaaa tatttcatga aatatttcat gtagaagcga gcaatacggt
    13081 tgcaaataac cattatcgtt taataagcag ttacgaaagc tcccaatatc tctaacgttc
    13141 agctcactcc atttcttttc ttcaaaaaaa tcagtgattc gtatctcttt ctatttgtcg
    13201 aaaaagttaa ctttaaaaag taacgccgaa aaaatatgca aaaaaataaa aaagcagtta
    13261 ctattgctag aataacatca aggaataata agttttggtt ttcagataat agtcgataag
    13321 ttgtgtattg gaattttaga tacagtaata aagtattttt catgaaattt tgtgagaatc
    13381 actattacaa gtatctttaa taaaattaat ggttaaggag gaacttaaag tagaatgtaa
    13441 atgaatagtt gtagtcagtc gattgtgata ctagactcaa agttgcagga ataagttttt
    13501 caatttgtga ttggaagata aaaaatgaaa aagaagggct tttttttata ctttgttgat
    13561 tgtagtgttt attttccctc tgtttagcca agtaacattt tctatgactc aaccagtttc
    13621 aagtgaggaa catgataacc tttttcgtgc tacagaagag tttaagaaat atcaggaaaa
    13681 tattgttccg gagactccat tagctagtga gccaattact gatattgatg gaaaccaaat
    13741 aggatggtat atacagtacg aagttatggt ggtaaataat gactcaatag taaaaaatac
    13801 agtaggctta gagctaacac cgattgaaaa ggtgagttca ttgttaacgt atatttatac
    13861 tgatgaaagt gacgagactg agatcatttt aacggattac tcaaaaattg ctactgataa
    13921 aaagtatata ttgtggatgt agacactagt gaaatacttt atgatataga aattgatgaa
    13981 aatttactag atgtagcaca agaaatcgat catcaaaagc aggaagctat tcgatatgct
    14041 ggtagaaaag ggaaaagaaa atatttatta cgtgaatgta gcaaaagtta gagaagatga
    14101 aaatgagtgg aaagaattca agagtcgcta ctcaattaac tcgactccga catttacagt
    14161 ttacagagaa ggatcgatag aaaaaactgt tttttggact aaagaaagtg gaatgtcttt
    14221 agctgaagta gaagagtttt tggattatgt tagtatgcaa cagtaaggga gttcttatta
    14281 tgaaaaattt tgacacatat tatgttattg ttttttcgat atctttgctg ttaatattac
    14341 taactttaat gcagtataaa gagtatccag agtattttat tttaactttt gtatatttag
    14401 taagtagcta cacacttcta tataaattca gaagttcttc tagagtttct aaagtttgtt
    14461 tcttaattag cttattgatt ctataatatt tttgatttat ataggaaatt aaaaatatta
    14521 tagaatcaac actcagagaa cgggttggtt tttaatagat ttaataagta ctgataatga
    14581 aatttctcct ggttgggaaa acgaagttgg ttaccctgta gaagaatttt ttcaagatta
    14641 ctttgcggag tatgccgata ggataatgag agattacgta acagataaaa ctcaagaagt
    14701 catcaatcaa tcccagtcat taaatgaatt atctgataag gcgaaagaag aagcagttgc
    14761 cattatttct tcagggatta gtgactatat tgatatgagt ggtgaaatca attatggcga
    14821 taaagacaaa attgtacgca tgataaaagc ttttatcaaa acttttgatg tgaaggcaga
    14881 tcttaagttt aatgatactt acctagtagg aaaattaatt aatatccttg ggacagagaa
    14941 agatacggaa acgtttattt cctctttgtc tatgttgttt acagataagc atttttcaac
    15001 tcagcttggt ggagaggaac tagtggaaat cttttaacca ttacgcccag cattaataaa
    15061 agtatatcaa aaaagtactc ctgatgattt ttaagattgg tttgagaaat aatgtgaaaa
    15121 cactattttt aatgttaatt atagatagag atgaacgcgt catatggtta aaagaatgaa
    15181 aaagtcaaag atacactgct atatttcact aaggatatag cagtgtatct ttcatgtcgt
    15241 ttcactggca gttttttata aaaggaggtg tgcatttcag ttgcttttct ttggtagtta
    15301 gttgaatcgt ttaagaatta acggatgtgg cagacaggtg ctctgtccaa aaaccagtaa
    15361 aatctttgat ggttccatct ttatttagct gtgcctgttc aaatactgtt ttgtttttac
    15421 cgaatggatc aattgcaata attgttccga tccccgcacg tttggcagca agtaatcctg
    15481 agtaagcatc ttcgataaca agacaatcag ccggagctaa gctcagtttg tctgccgctt
    15541 taagaaaaat atccggttgc ggtttcccag ggaaagagcc gtcgtcatag acaatcttgt
    15601 cccagtcaaa ccagcgggct aaatcgaaaa tatcaaaata aaaagcaaca ttctctttga
    15661 cagtagccgt ggcaatcgtt aatggaatct gttggtcagt cagctggtca agagtcgctt
    15721 caagcccttt tgtcaactga agctcgtttt cattttgcaa gcaaagcata cgataatagc
    15781 tttctttttc ttctgacaat acggcgatct cagaggcggt caaatgctct gaaatgaaat
    15841 gtttcaaaat ctccgtattc gtccgaccat gaatattttt taaaatatcc tcgtctgata
    15901 aaccatcttt tgtatgatca tgtatcatat gcagccaagc agcttcatgc agatgagagt
    15961 ccaaaaacat tgttccgttg aaatcaaata taatcccttt catagttacg ctcctatagt
    16021 ggtattttcg gttgaatcag caatttgcag atcgacatat tgtgcatagt gctcttgaac
    16081 ctcccgcgag atctggcgat ccgtaatgag cagatcgaaa tcatgcaaat tataaaacac
    16141 ataaaaatca tctcgattga attttttatt atcaacgagt agatatttct tacgggaatt
    16201 atttagagcg atctgctgtg cttctccttc ttcggtactg taagtagaga tcgcttcgtt
    16261 gtgaacgcca tttgaactga taaatgcttt tgtaaacttt agtcttctta aattgtcgtt
    16321 ggtgatcggt ccgacaaatg cgccggtatt tttccggaaa tcaccgccaa tcagtagaat
    16381 ttctggtcca tctgcttgag caagaatatc aaaaactgga taattatttg taatgatccg
    16441 aattttcttg ttcagtaaat gcgtcgccaa tagttcgatt gttgtacctg gtcctaagaa
    16501 aatcgtttct ccctcgtgaa tcaaggaggc tgctgtggca gcaatttctt ttttttcttg
    16561 aatctgcaga gtggcttttt cagtgtgaga aagttcttga tctaaagtgt aggaaagact
    16621 ttgagcccct ccatggacac gcagcagctt gcccgatttt tctaattcat ctaaatctct
    16681 gcgaacggtc atatcagaaa catctaattg attgatgatt tcattaacgg taaggattcc
    16741 ttttttattg accatttcta cgatagtaag caatctttct tttttcaaca ttgtcttcac
    16801 ctctaattta aggataatct atcatataaa cggacaacag tcaatctaat tcgaacaaaa
    16861 gtaaacattt agggtggttt ttatgtttgt tacaatagat tttattgctg ttttctggtt
    16921 tttatgatta tttgtgtttg tttttgttga caaatgtttt ggatgcgttt acaatgcaat
    16981 cagttagaaa gagcgaaaac tgattataga tttgaggaga gatgtacatg cttaaattac
    17041 cagaagattt tatttttggc ggagccacag cagcctatca ggttgaagga gccactaagg
    17101 aaggtggcaa aggcgctgtt gcttgggatg actttttaga ggaacaaggg cgattcagtc
    17161 ccgatccggc aagtgatttt tatcatcaat atgcaaagga cattgaattg tgtgaacgtt
    17221 ttggtgtaaa tggtctaaga ttatccattg cttggagccg catttttcct gatggagctg
    17281 ggaaaccaaa tccagaagga atcgcttttt atcatcgtgt gttcgaagaa tgtaagaaaa
    17341 gaaacgtaac gccgtttgtg acgttgcatc attttgatac ccctaaacgt ttgtttgacc
    17401 atggagattt tttgaatcga gaaacaatag aagcatttgt ttcctatgcc attttttgtt
    17461 ttcatgaatt caaagaagtc aaggtgtgga gtacctttaa tgaaatctat ccagttgcaa
    17521 ccaatcaata tttgttaggt gttttcccac caggaatcaa atatgatttt acaaagatcg
    17581 tcgcctgtct tcataatatg atggttgctc atgcccgtgt agtgaactat ttcaaagaaa
    17641 acgaacttcc gggtgaaatt ggtgtagttc actcattaga gacgaaatat gcggcaacag
    17701 acgcgccgga agataagcat gctgcctttt tagacgatgc attgtcgatc cgtttcttat
    17761 tagatgctac ctatttaggc tattattcaa ctgaaacctt gactgctctt gatgagatat
    17821 gtgaagcaaa tcaggccagc tatcattttc ctgaagaaga tttcgttgaa ttgaaaaaag
    17881 catccacgcg taatgactac ttagggatca atcactacca atgccatttt gtcaaagctt
    17941 acgatggaga aaatgcaatc catcataacg gtacgggtga aaaagggacc tctgtttata
    18001 aagtgaaggg aatcggagaa cgtatttata aagaaggaat tcctcgaact gattgggact
    18061 ggctgattta tccagaaggt ctatatgact tgttgctgcg aattaaaagc gattacccac
    18121 attacaacaa aatctatatc actgagaacg ggatggggta taaagatcag tttgaagatg
    18181 gcattattat ggatcagccg agaatcgact atttgagagt ctatttggaa tccttaagca
    18241 aggcgataac agccggggta aatgtgaagg ggtatttttt gtggtcgctt atggatcttt
    18301 tctcatggac aaatgggtat aacaaaaggt atggcttgtt ttatgttgat tttgaaaccc
    18361 agaagcgtta cccaaaagaa tcagcttact ggtacaagtt ggtcagtgaa accaaaacga
    18421 ttatttaata agtgataatg gaggaagaaa agatgaataa agaggaatta caaatgcttg
    18481 gttttgagat cgttgcatat tcaggcgacg ctcgcagtac attattgaaa ttattgaaag
    18541 aagtaagaca aggaaacttt gaacatgttg attcggcgtt gaaagaagcc gacgaaaatt
    18601 taacccttgc acataattcg caaacaaaaa ttttagcgga agaagcatct gggaaagaga
    18661 tggagatggg attcattttt atccatgggc aggatcattt aatgaccact ttattgctga
    18721 gagatctgat tcaagacttt attgtactgt acagacagaa tcaaggatag gagaagaacg
    18781 ctatggatgg aatcattaaa caaatcgaaa aagggaaacc attttttgaa aaaatctcac
    18841 gtaatagtta tttaggagcc gttcgtgacg gatttttaac agcgatgcca gctattttat
    18901 tttcaagcat tttcattttg attgctgcgg ttcctgagat ttttggttac caatggcctg
    18961 aatctgtctc cacatggcta tggaaagtct ataattattc gatgggtgtt gtagggttac
    19021 tcgtttcagc aaccactgct cgctgcttgg ctgattcgat gaatcgtcgc ttaccgaaaa
    19081 acaaagtaat caacaccacc tctgtgatgc tggcctctgt ggtaagtttc ctgttgttaa
    19141 gcgtctctcc gattgaaggt ggattttcaa cggaatatat ggggacaaag ggactactgg
    19201 cttcctttgt cgctgcattt ttaacagtta atttatataa gttttgtgtg ctgaaagata
    19261 ttaccattaa aatgcctaaa gaagttcctg gaacgatttc gcaaaccttc cgagatattt
    19321 ttcctttctc tttttcagta tttgcggccg ttttaattga tttaggcatt cgacaaatct
    19381 tccaaatctc atttgcagaa gcaatcatta cggtgctgca gccgctattt acagcagctg
    19441 acgggtactt aggaatcgct attatctggg gagcgatggc gctgttttgg tttgtcggtg
    19501 ttcatggacc gtcgatcgtg gagccggcaa ttgcggcaat tatctatgcc aatgtggaaa
    19561 ccaatctgca attgttcaat tccggtgaac aagcttctaa agtactgacg gtgggtttag
    19621 ggaattttgt aggaactatg ggaggaactg gggcaacatt ggttgttcct tttatcttcc
    19681 tactctttgc taagtctaag cagttgaagg cagttgggaa agcttccttt attccagtaa
    19741 gtttcgctgt caacgaacca ttgctatttg cggcacccat gattttgaac ccttattttt
    19801 ttattccatt tttgttaaca cctgttgtaa acgtttgcct gttcaagttt tttgtcgatg
    19861 tattgggcat gaacagcttt atgtacgttt tgccttgggc aactccagca ccgatcggtt
    19921 tggttctagg aacgggcatg ggtatcttag cttttgttct agcagcggtt ctaatcgtcg
    19981 ttgacttcct gatctatcta ccattttgca aagcatacga tgctgtctta gtagagaaag
    20041 aagcacaaaa agcagaggtg atcgcaaccg aggaaggtgc ttctgccgat gtacgtgagg
    20101 aagtacctgt ggcagcgagt caagttatca gcgatgcaaa taaagaaatc aatgtgttgg
    20161 tactttgtgc tggcgcaggg acaagtggga tgttagctaa tgctttaaaa aaaggtgcat
    20221 ctgaatcgaa agcaccgatc agtgcaatgg cgggtgctta tggttctcat tacgaaatgc
    20281 tgcaggattt tgatatggtg gtcttagcac cgcaagtcaa ttcttactat gatgatatca
    20341 aagaagacac cgatcgctta ggaatcaagc tggttgcgac aaaaggagca gaatatatcg
    20401 gattaacgag agatcctgaa aaagctgttc agtttattct gaaccaattt caataaagga
    20461 ggagccataa tgaaaatggg aatttggttg cgtaaagctg ttttatttgc agctgtgtta
    20521 ggggctttgg gggctgtttc aaaaactgtt gaagcatctg ccagcgaatt tattcgcgga
    20581 gcagatattt cgatcctgtc agatatggaa aaatctggtg caaaatatta tgaagacgat
    20641 atttcaaaag atgccttaga gattttaaaa aataatggtg tcaactatgt tcgactgcgt
    20701 ttgtggcagg atccttataa tagtaatgga gaaagttatg gagcagggac aaatgatctg
    20761 gaaacgacga ttgaccttgc aaaacgagca aaaaatctgg gacttaaggt gctgctggat
    20821 tttcactaca gtgatttttg ggttgatcct gggaaacaga atcttcctaa agcatggcaa
    20881 ggtctgacct ttgaagaaat gaatacggca ttgtacgact atacaaagaa cgttctgtcg
    20941 gaaatgaagc agctggacgt ttatcctgat atggttcaga tcggcaatga actgaatagc
    21001 ggaatgctct ggccttatgg caagtcttgg ggagaaggcg ggggagaatt tgatcgattg
    21061 gctgcttttt tgaagtctgg tatccaagct gttcgagaca ctcaacctaa aacaactcca
    21121 gtaatgctcc acttagctga tggtggcgat acaggagcat ttacttggtg gtttgatgaa
    21181 atcacgagtc gaggtgtgtc atttgattta attggagtgt cgtattatcc gtattggcac
    21241 ggttcaatga atgaacttca aaccaatatg aatgcgatca gccaacggta tggtaaagaa
    21301 gtgatcgtag ttgaaacagc ttatgggcat acaacagcga atgccgatac tatgccaaat
    21361 gcttttggtg aagccgaagc agctgcgggg ggatatgaac caacaccgac aggacaagca
    21421 gagtatttgc tggatcttgc cgatcggatt caggcagtac cgaataatcg cggggcgggc
    21481 ttcttctatt gggaacctct ttggtacaac ggaaatgtga gttgggcaac acaagcaggt
    21541 atgaattatc tcagtgttca atccactatg ggaaacgaat gggacaacca agcgatgttt
    21601 gattttgctg gaaacgcctt gccaagcttg cgtgcgttta aacaagcagg ggcgcaaata
    21661 aatctagtta aaaatgcaag tttcgaaagc gatggaccaa cgaccagtcc ttccaattgg
    21721 caaacctggt ttcaacaagg aaccgctaag ggtacgatca aaacggaagc gggcactttt
    21781 tttggggact acaaactaac tttttggcag gatcaagcat acgaggcatc agcttatcaa
    21841 aatgttagtg gcataagcaa aggaacttac acattgagtg cctatgtaat gtctggggga
    21901 gagtttgata ctaatcagtt atatatcaaa aattatggtg gagcggaact aaatactgcg
    21961 gttgttaaaa caagtgaatg gacaaaaatt acaatcaaag acattccaat tacaacaggt
    22021 gtttgtgaaa ttggggttta tagcaaggct tcaggaaatg cttggacgaa cgttgatttt
    22081 gtttcattgg tgaaacaata gactgcggat cgtttcgatt caagatcgga ggttcccttc
    22141 agccacatcg ttagcgtaga aggcaggaat cgaacctgca cctcgccttt gccaaaaata
    22201 accagaaacg atttccagtc atttttacca aaacgagtaa agcaccagac ttcatctaca
    22261 ctttgtatta tgctaaagag agttcaacga tttcgtaaga agcaatgaaa aaattgcaaa
    22321 aagttgtgca gataacataa agtttgttta agaaagggta accttagaat tccgtcgtga
    22381 atatgatttg agcacttaga tggatagaaa aaagttctcg gaaaacagtt cgtttttcga
    22441 gaacttcttt ttatgataag aatgaaacaa attaacttat attatagtct cttttggtag
    22501 ggaaccatct tatttttaat gaaaatcaag cattttagct attgaagaat gttgatttat
    22561 agggattccc cctccatatt atgttggctc tttattccca ctccactgtt gctggtggtt
    22621 tagaagtgat gtcatacacg atacggttga cgtgggctac ttcgtttacg atacgtacag
    22681 agattttttg caagacttcc catgggatac gggcaaagtc agcggtcatt ccgtcgattg
    22741 aagttacagc acggataccg actgtgtagt cgtaagtacg tccgtcaccc ataacaccga
    22801 cagagcggat ccctggaaga acagtgaaat attgccagat atcacggtca agtccagcag
    22861 ctgcgatttc ttcacgcaag atagcatcag attcgcgtac gatttctagc ttgtcttcag
    22921 tgatttcgcc aagaacacga ataccaagac caggaccagg gaatggctga cgccaaacga
    22981 ttgaatcagg catgcctaac tgagtcccta attcacggac ttcgtctttg aataatgtgt
    23041 ttaatggttc gatcaattca aattgcatat cttctggcag tccacctaca ttatggtgag
    23101 atttgatcgt ctgtgctgtt tctgtaccag attcgataac gtcagtatac aacgttcctt
    23161 gtgctaggaa agagacgcct tcttcaccag caagttttgt tgcttcgtca tcaaaaacat
    23221 atacgaattc attcccaatg attttacgtt tttgttctgg gtcagataca cctttcaact
    23281 tgtctaagaa gcgatctctt gcattgactt tgatgatgtt caagccgaat tttccgccta
    23341 gactttccat tacttgttcc gcttcgcctt tgcgtagcag accgtggtca acaaagatag
    23401 atgtcaattg gtcaccgatc gctttttgta aaagaacccc aacgacacta gaatcaacgc
    23461 cacctgaaag accaagcaag acttttttgt caccaacttg ttcacggatt ttttctactt
    23521 gcatatcgat aaagttatcc attgtccagt taccttcaca gtgacaaaca tcaaaggcaa
    23581 agtggcgcag caattcgatt ccgtattcgg aatgacgtac ttctgcatgg aattggatac
    23641 cataaaaatt acgtgttgtg tcttggatag aagcaatcgg acaatctttg cttgttccga
    23701 ctgtttcaaa gccttcagga actttagtta ccaagtcacc atggctcatc catactgttt
    23761 gttgttttgg tgtttcttta aacaagacag cttgatcgct tgttacttct aacaaggctt
    23821 tcccatattc gcggttttta gcaggctcta cggaaccgcc aagtttgtac gtgatcaatt
    23881 gcataccata gcaaatccct aatacaggaa tacctaaatt gaagatctca ggatcgatcc
    23941 caaatgcatt ctcatcatat acactgtttg gtccgccaga aagaatgatt ccctttggat
    24001 tcatcgcttt tacttcttct gcagtaatgc ggtggctcaa taattcggaa aagactccaa
    24061 gatcacgaat acgtcttgtg atcaattggt tatactgact accgtagtct aatacgataa
    24121 tcttttcaac gttcgtcata tcggcaacgt ttgtcaaatt tattacccct atccctttaa
    24181 attttatctc aaaatagtca aactatttta aaatgctaat attttcgcat gaaaatcgaa
    24241 tcgatgatat gattttcagt tttatggaga attatatcgg ctcttcctcg tgtaggcaag
    24301 atatattcct gtaaattttt caaattcaca tttttccata catcttttgc cattttaaag
    24361 gcttcttcac gatctccgat agcaaaacga taataataat tctctggatt ttggaaagcc
    24421 gtatccagta acgcaccaaa acgatccaaa taccattttt cgatcagcac gggatcggca
    24481 tcgacataga cagaaaaatc aaaaaagtcg ctgacgtaga tttgctgatt cgcaggtaat
    24541 tgaagcgtat tgatcccctc aacgatcaag atatcaggct gctggatcaa ttcgtacttg
    24601 tctggaatga tatcatacac atcatgtgag taaacaggta cttttatctc ttcctgacca
    24661 gattttacac ggttcaagaa atcgatcagc atctccatat cataactttc aggaaatcct
    24721 ttacggtcca tgattccacg ctcttttaat atacgatttg gataaagaaa tccgtcagtc
    24781 gtgatcagct gaacgtttct tcgtttgaag gtacgagaca aaatcgtctg cagcagtctg
    24841 gctgttgtac tttttccaac ggctacactt ccggcgatcc cgataataaa aggcggtact
    24901 tctacgtatt tatgaagaaa taaaccttta ctcaagaaca aagattcaaa ttctttcata
    24961 taaagataaa tcagatgagc aagaggtaca tagatatctc gaacatcctg catggaaatg
    25021 cggtcattca aacttttgat attatctagt tcatcttgtg tcaaaggtgc ttgcccatta
    25081 cgataaaatt ctcgccattc ttctcttgcc acacggtagt agttcattgg atcattcata
    25141 ttagcctcct gcgttctccc atcaatggaa ctattttaac acaaaataaa cgcaaacccc
    25201 accacttaag agagattgcc gatctttttg tataatcttt ataatagaaa gaaacggagt
    25261 cttattcttg acttgcgcac ggatacataa aaggatagac tgttgtcatg aaagaaatga
    25321 gaaggatgga agacatgaca aatcattact attctgaacg cccagatacg gcgcacgatt
    25381 ttgaacaatg ggcttttgag ttaaaaggca gaacctttca atttgtaaca gattctggtg
    25441 tattttcacg tgaaacagtg gattatggtt cacgtgtcct gattgatgct ttcgattggg
    25501 aagagttacc tgatgaagga aagatcttag atgtgggatg cgggtatgga ccgattgggt
    25561 tagctttggc atttgcgaca cagcggtttg ttgaaatggt cgacattaat gaacgagcgg
    25621 taagtctagc gcaaggaaac gcaaagcgta accaaatcga acatgttgat atccatcaat
    25681 cgaatatcta tgaagcagtt catgaagaaa cctatgcagc tatcgtaagc aatccgccga
    25741 tccgtgctgg aaaaaaagtt gtacatgaaa ttttgacagg cgcatatcct cggttgaaga
    25801 agggcggtac actgacaatt gtgatccaga agaaacaagg agcgccgagt gcgcaaaaga
    25861 aaatggaaga aacatttggt aatgcagaaa tcgtcacaaa agataaagga tattatatca
    25921 tcaaaagtgt gaaagaataa ctagctgaaa aatagtggag cgacgaaaga gtggaactgg
    25981 gcgtgcatgt acgggtacgt atcagttctt tttttgttga gaagttttta aaaacaaaga
    26041 actatttttt cttcaaaaag aaatagtagg aacagagtcg ttgtttttta cgataaaata
    26101 aataagatac agaacttgta tagaaggctg ccaagtcggt agataaagga ggtttttatc
    26161 aaaaaacata ctttcctttt ttctctattc ttttcttggg ggttttggta cactgatagg
    26221 gaatttagat agaagggagc caataggatg aagctgacca tcagagatat cgcagaaatg
    26281 gcaggcgtat cagtaacaac tgtctcacag attttgaata acaaaggaag cagatttagt
    26341 gataagacaa gaaaaaaagt gttgtcgatc gtgaatgaac atcattataa gcccgattat
    26401 ttcgcttcaa atgtgatcaa tcgacattca aagaccatcg gaatgatcgt ccctgatgtc
    26461 actgatttct tcttctccaa actgatcgaa ggtgtagaga gctatttgaa tcctttgggc
    26521 tatgtgatca tgttatgcaa ttctcgtcat agccaagaaa atgagatcaa gtatttacaa
    26581 gagctttccc accgctcagt ggacggaatc ttgctggcca caccaaatat tttacctgag
    26641 aaatatgcat tagacagcgg tttttatcaa aaaatgccaa tcattttaat cgatcgcgga
    26701 ttgaatcgtc gggataacgg acggcttatc gtaaaggaat atgagggcgc ctatcaagct
    26761 gtttcgctgt ttattgaaaa tggccatacg aagatcggca tgctgaagga aaccactgga
    26821 tactatcaat tagaagaacg tttcaacgga tatcgtcatg cgctgaaaga tcatggcctg
    26881 ccttttaatg ggaaatttgt tgaacatgga gagttgactg tccaaggtgg atatactgca
    26941 tcaaaaaaat tactcaaaca taaagatatc acggctattt tttgcgggaa tgatgccatg
    27001 gcgatcggat gctatcaggc gatcgatgaa ttgggcaaaa aaatcccaga agatatctca
    27061 gtcataggat tcgatggatt aaagctgtca gaatacatga ttccgcaatt gacgacagtg
    27121 cagcagccaa gttttgatat tggattttat gctgcacgtt tcctgatcga tacgatcgaa
    27181 tttcctcaaa gaaaagttcc gaacaaagtg ttcgaaacaa aattaattat tcgtgagagc
    27241 gtaaaagtat tgacaaaggg ctaactcggc ggtatattgc ttatgtaagc atttacaaag
    27301 gctagttagt gcttttttta tttttagtaa accagtttac taaagtggtt tacctttcct
    27361 aaaaataatg tataataccg aatgaagaca aggaggatca ggcaatgcga atggtggatc
    27421 tgattgaaaa aaagagggat ggaaacgagc tgtcgaaaga ggaaatcgag tacatcgtca
    27481 cgaactatac gaatggaaag attccagatt atcaagtcag tgcattattg atggcaattt
    27541 tttatcaaga catgacaaat gaagaaatca cgaacttaac attggcgatt gctaattctg
    27601 gtgatgtcat cgatttgagt tctcttgaag gaataaaggt agataagcat tcgacaggtg
    27661 gcgttggtga cacgaccaca ttgattttag cccccctagt agctagtgtc ggagtgacag
    27721 tggctaaaat gtctggacgc ggtctaggtt acacaggtgg tacactagac aagctagaag
    27781 caattcccgg atttcagatc gagctttcgg atgaagaatt tgtacgcatt gttaatgaaa
    27841 gtaaagtagc ggtaattggt caatcaggaa acttggcacc ggcggacaaa aaattgtatg
    27901 ccttgcgtga cgtcacagcg accgttgatt ctcttccgct gattgccagt tcgattatga
    27961 gtaaaaaaat cgcggcagga gcagatgcaa tcgttttgga tgtgaccact ggagacggtg
    28021 ctttcatgaa gaacatcgaa gatgcaagac gtctggcaaa gaccatgacg agcattggga
    28081 aactggctaa ccgagaaaca gtggcggtta tctcagatat gtcagaacct cttggcgaag
    28141 ctatcggaaa tagtctagaa gttgtcgagg caatcgaaac attacaagga aatggtccag
    28201 aagatctagt agaaatgtgc tacgccttag gaagccaaat ggttgttctt gctggcaaag
    28261 ctaagacaac cgatgaagca agaacgttgc ttcaagaagc tctggaatca ggtaaagcgt
    28321 tagcaaaatt caaagaaatg atccaaaatc aagggggaga cccagcgatc gtggaacatc
    28381 cagaacgaat tttgactgca cgctacacaa tggagcttcc tgctaaacaa agcggagttg
    28441 tgtcaaaaat cgtggcaaat gaattaggaa ttgctgcaat gatgctaggt gctgggcgta
    28501 aaaccaaaga agaagatatt gatcacgctg ttggattgaa actgcataaa aaaattggtg
    28561 acactgtgac aaaaggtgag tcactattga cgatctatag taacgacgaa gaaatcactt
    28621 ctgtcattga attattatat aaaaatattg aaattggtga atcggcaatg aagccaacgt
    28681 tgattcatga catcatcaca gaataaagga aaaaagcgga ctttaccgtt ttaaagaaaa
    28741 ggggaaaaga aatggaacta aaccgaatga tcgaccatac tattttgaaa gcagacgcat
    28801 ctaaagaagc tgtgatgcaa attatcgaag aagcaaaaaa ataccatttt tattctgtct
    28861 gcatcaatcc agcatgggtt gcgctagcga aagaacaatt acaaggtgag ccagtagccg
    28921 tatgtacagt aatcgggttt cctctaggag caaacacacc cgagacaaaa gcatttgaaa
    28981 caacagatgc catcaataac ggtgcagatg aagtcgatat ggtcatcaat atcggtgctt
    29041 tgaaatcaaa ggatgatcaa caagtccaaa aagatatcga agcagttgtt gaagcagcaa
    29101 aagatcgtgc gcttgtcaaa gttattattg aaacatcgtt attagataga gaagaaatca
    29161 tccgagcttg cgaaatagca aaagctgcag gcgctgattt tgtcaaaaca tcaactggtt
    29221 tctcaacagg cggagcaaag gtagaggatg tccgtttgat gcgtgaaact gtaggaccag
    29281 aaatgggtgt caaagcttcc ggcggtatcc ataacgaaga agaagcaatg gcaatgatcg
    29341 aagctggtgc tacaagaatc ggaacaagcg caggagtagc aatcgtatct ggttcaactg
    29401 gtgaaggcta ttaatttttt caaaggagaa gctcatggca gaactcaaac aagaatggat
    29461 caacacagct attgaagcgt tagataaagc ctatgttcct tattcccatt ttccggtagg
    29521 cgcttgtctc gtaacggaat caggcaagat ttatcaaggc atcaacattg agaatgcatc
    29581 atttggatta acgaattgtg ccgagcgcac agcttttttc aaagcagtat ctgaaggaga
    29641 aaaaacattt acgcatctag tcgtagcggg gcacaccccc gatcctatct ctccttgtgg
    29701 tgcatgtcga caagtaatgg cagaattctg ttcccctgat atgccggtta cgctagtagg
    29761 agacaatggt gtgacgaagg caacgaccgt tcgtgcactg ctgccttatg catttactga
    29821 aaaagatcta taactcatgt tcattcagtc agctgactgt tgaaaaataa aacaattatt
    29881 ttaggaggct ttacagaaat gaaaaaagca aaattatttg gtttaggtgc tgtcgcacta
    29941 gcagcagggt tatttttagg tgcatgcggc aacaacggct ctactgattc atccggtggc
    30001 aaaagctcat cagacacaac aactgcagca ttgatcacag acacaggtgg tgtagacgac
    30061 cgttcattca accagtcagc ttgggaagga ctagaaaaat gggggaaaga tcaaggactt
    30121 tcacgaggaa atgatggctt ccaatatttc caatcttcaa atgaatcaga ttacatccca
    30181 aatattgacc aagcattgaa tgctggattc aaaacgattt ttggtattgg ttataaacta
    30241 aaaccagcga tccaagaaca agcaacaaac aatacaggta cgaactttgt tattatcgat
    30301 gatgtcatcg atggattaga taacgttgta tctgcaactt tcaaagacaa cgaagcttct
    30361 tatcttgcag gtgttgcagc agcttatacg actgaaacaa acgtagtcgg ctttatcggc
    30421 ggtgtaaaag gtgaagtaat cgatcgtttt gatgctggat tcaaagccgg tgttgatgca
    30481 ggtgcgaaag aattaggaaa agaaatcaaa gtattgaatc aatatgctgg tgacttctct
    30541 gctccagata aaggacgttc aattgctcaa ggtatgtatg cacaaaacgc agatatcatc
    30601 ttccatgctt caggcggtac aggtaacggt gtattccaag aagcaaaatc attgaacgaa
    30661 tcaggcgaca aaaaagtttg ggttatcggt gttgaccgcg accaatcaga cgaaggcgaa
    30721 tacacattaa acggcgaaaa gaaaaacttc acattgacat ctacactgaa agcagttgga
    30781 acagtagtag aagatttggc acaaaaatca gcggacggta aattccctgg cggcgaacac
    30841 actgtttatg gattgaaaga agacggtgtt ggtctaacag aaggacaact ttctgacgaa
    30901 gcgaaaaaag cagttgatga agcaaaagaa aaaatcattt caggtgacgt aaaagttcca
    30961 gaaactcctg aagaaaacta aaaccatttc tatagccttg ttagacacat gtttgacaag
    31021 gctatggttt gattagaaca agaattgttc atttatccaa gctgccttgt gacagtttgg
    31081 ataagggaac aactccctga agtaatgttt gtttcaaaag aagaacgctc actaagcgtg
    31141 aatcttagtc aatcgttgcc ctagatagaa atcgttagga tgtgaaaaaa aggtggttca
    31201 agaaaatatt gtcatagaaa tgcagaatat taccaaagaa tttggaacat tcaaggcaaa
    31261 tgacaacatc aatttacaag taaaggcagg agaaattcat gcgttgcttg gagaaaacgg
    31321 tgctggcaaa tctacattga tgaacgtgct ttccggatta ttagagccga catcagggaa
    31381 aattttgatg cgtgggaaag aagtaaagat cacaagtccg accaaagcca accaattagg
    31441 gattgggatg gtccatcagc actttatgct tgttgatgcc tttactgtaa cagaaaacat
    31501 cgtgttggga agcgagccta gtcgcgcagg gatgcttgac cataaaaaag cacgaaaaga
    31561 gatccaaaaa gtttctgaac agtatggatt gtcagtcaac ccagatgctt acgttcgtga
    31621 tatttcagtt ggaatggaac aacgggtaga aattttaaaa acactttacc gaggagcaga
    31681 tgtactgatt tttgatgagc cgacagctgt attgacccct caagaaattg atgaattaat
    31741 cgtgatcatg aaggaattag tcaaagaagg caagtcgatc attttgatta cgcataagtt
    31801 agatgaaatc aaagcagtag ctgaccgctg tacagttatc cgccgtggaa aaggaatcgg
    31861 tacagtcaac gttaaagacg taacctcaca acaattagcc gatatgatgg ttggaagaac
    31921 ggtttcattc aaaacgatga aaaaagaagc gaagcctcaa gaagtcgttt tgtctattga
    31981 aaatctagtg gtgaaagaaa atcgtggatt agaagccgtg aaaaacttga acttagaggt
    32041 tcgtgctggc gaagtacttg gtatcgctgg aatcgatgga aacgggcagt cggagttgat
    32101 ccaagctttg actggtttgc gaaaggcaga aagcggacat atcaagctaa aaggggaaga
    32161 catcactaat aaaaaacccc gaaaaatcac tgaacatggt gtaggacacg tgccagaaga
    32221 ccgtcataaa tacgggttag tcctagatat gacattatct gaaaatatcg cactacaaac
    32281 ctatcatcaa aaaccttaca gtaaaaacgg catgctgaat tattcagtaa tgaatgaaca
    32341 tgccagagaa ttgatcgaag aatatgatgt tcgaacaacg aatgaacttg ttcccgcaaa
    32401 agctttatca ggcggaaatc agcaaaaagc aattatcgct cgtgaagtcg accgagatcc
    32461 tgatctgttg attgttgcaa atccaactcg tggactggat gtaggtgcga tcgaatttat
    32521 tcataaacgt ctgatcgaac aaagggacaa atacaaagca gtgttactga tcagtttcga
    32581 attagaagaa attttaaatg tttcggatcg tattgctgtt atccatgaag gagaaattgt
    32641 cggtatcgtt gatccgaaag aaacatctga aaatgaatta ggtctattga tggcgggcta
    32701 taccttagaa gaagcacgaa aagagttaga aaagggggct ggcgcacatg aatgatcgca
    32761 gcgaaaaatt ccgtaattta ttagtgcctg tactttcagt tgttttagga ttgatcttag
    32821 gcgcgatatt gatggctgct tttggttttc agcccatcca aggttattct tctatgctag
    32881 atgcagccct tggttcgcaa agagggatag gtgaaacgtt aaggcaagca acgccgttga
    32941 tttttacagc attaggtttt tctgtagcta actcagctgg gtttttcaat attgggcttt
    33001 ctggacaagc actttgcggg tggatcgtca gtgtctgggt ggcacttgcg tttccagatc
    33061 tgccaaaagt tgttttgctt ccgttatgcg tgatcttagg tgccttagct ggtgcgatgg
    33121 cagcggctgt tccaggttta cttcgagcat tttttggaac aagtgaagtg atcgtaacaa
    33181 tcatgatgaa ctatatctta ttatacgtaa gcacatttgc tttacatgaa gtgatgcctg
    33241 aaagctatcg ctcaagtttg gactcttcca atatgatcag tcaaaatgcc tcactgcggt
    33301 taccatggtt aacacaagct tttggcggct ctcgcgtaaa ctcaggatta tttttagcaa
    33361 tcatcgcgct tattttcgtt tggctgctga tgaagaaaac gactttagga tttgaaatcc
    33421 gttctgttgg attgaatcct tttgcttctg agtatgcagg aatgagtagt aaacgtacga
    33481 tcgttttgtc gatggtcatt tctggcgctt tggcagggct tggcggtgtg gttgaaggat
    33541 taggaacgta tcaaaacttc tttgttcaaa cgacttcgct atctattgga tttgacggaa
    33601 tggctgtttc cttgcttggt tctggatcag caatcggtat tcttttatca gcgatcttgt
    33661 tcagtatttt gaagatcggt ggacttggca tgcagacagg agcaggtgtt ccgtttgaga
    33721 tcgtcaatgt atcgattgct ttgattatct tctttgtcgg gatcaacttc ctgattcgtt
    33781 tcgtcatggc taaagtcttc caagggaaaa aacaagaaga gatcgttgcg acaatagaat
    33841 cgaaaccaac gaatcaaaac catgaagggg gcgaactata atgtcgacta tcgaattaat
    33901 tgccttgatc cttacttcta cactggttta ttcaacaccg ctaattctaa cgtcactagg
    33961 cggaactttt tctgaacgaa gcgggatcgt aaacgtaggg ctagagggaa tcatggtcat
    34021 gggtgctttt agttccatcg ttttcaactt gacgatgagt ccatcacttg gttctatgac
    34081 accatggatc gctattttag tgggtggcgt cgtaggtatc ctattttctc tgattcacgc
    34141 agtagcaaca gtcagtttgc gtgctgacca tattatcagc gggacagtaa ttaatctgat
    34201 ggcacctgct ttaggtgttt tcttgatcaa agcatggtat ggtaaaggtc aaactgataa
    34261 catcacgcag aatctggggt atttttcttt cccaggatta gcagatattc cggtcattgg
    34321 accaattttc tttaaaaata cattcttacc tgcttattgt gctattttga ttgctgtcct
    34381 agcttgggtg atcatcttca agacgaaatt cggcttgcgc ctccgttcag ttggtgaaaa
    34441 tcctcaagct gccgacacat taggtatcaa tgtatatgct atgcgttatt caggcgtact
    34501 gatttctggc ttgttaggcg gtatgggcgg tgctgttttt gctcagtcga tttccggtaa
    34561 cttttcagct ggtacgatcg ttggacaagg gttcatctcc atggctgcta tgatctttgg
    34621 taagtggaat cctttagggg caatgggtgc ctcattgttc tttggttttg ctcaaagctt
    34681 gagtatcatt ggcgcacaat taccagttat ttcttcgatt ccgccagtat tgctgcaaat
    34741 tgctccatat ttgctgacaa tcattgtgct ggttgttttc ttagggaaag cttctggtcc
    34801 aaaagcaaac gggaagaact atatcaaatc aaaataatct tttagcgaat aaaaagggtg
    34861 ggttacggga agtgtttttc gtctcgccct ttttgtttta aaggcaataa aaataaaaag
    34921 aaagaaggaa taatcatgtt taaacgcgta catctgatcg tcatggattc agtaggaatt
    34981 ggagaagcac cagatgccga taagttcggt gatgttggtt ctgatacatt aggacacatt
    35041 gcgaaagaag caggattgaa cgttccacat ttagagcagc ttggtttagg aacgatccgt
    35101 cctcttgaag gtgtggaatc agtgaaagat catcaaggct atgcgacgaa attagaagaa
    35161 gtttctgtag ggaaagatac gatgacaggc cactgggaaa tcatgggatt gaatatcaaa
    35221 actccatttc gtgtgtttcc taatggattc cctgatgatc tgatcaaaca aatcgaagaa
    35281 ttttctggcc gtaaagtcgt atgtaacaaa ccttatagcg gaacagctgt tattgacgat
    35341 tacggtgaac accaaatgaa aacaggcgat ttaattgtat atacttctgc cgatcctgtc
    35401 cttcagatcg cggcacatga agaaatcatt cctttagaag aattatatcg gatttgccaa
    35461 ttcgttcgtg atataacaaa agatgatccg tatatgattg gccgaatcat tgcacgtccg
    35521 tacgtgggtg aaccaggaga cttcacacga acaagcaatc gccatgatta tgcgttgaat
    35581 ccattcggac acacagtcct tgattctttg aaagaagcag gaaaggacgt gattgctgtt
    35641 ggaaagatca acgatatttt caacggacaa ggaatcactg aatctgtccg cacgaaaagc
    35701 aatatggatg gcgttgacca gctgctgaaa gttatgaaaa acgatttttc aggaatcagc
    35761 tttaccaatt tagtagattt tgatgcatta tacggtcatc gtcgggatgt agtcggctat
    35821 gcgcatgcga ttgaagaatt tgacttacga attccagaat tgcttgaagc gatggaagaa
    35881 gacgacttgc taatgattac agccgatcac ggaaacgatc cgacgtttac tggtaccgat
    35941 catacgcgag aatatgtacc gttattggtt tacagtaaaa aaatgaaaga acaaggggca
    36001 ttgcctcaag gatattattc agatatttca gcaacgattg ctgagaactt tagtgtttct
    36061 tcgactgaaa atggcgaaag cttcttgaaa ttattaaaat aatcttttta aataggagaa
    36121 agcaaatgac caagttaagc gagatgttac aagaaacgac ccagtttatc cttgataaag
    36181 gagtaaaaga aattgatttt ggtttgattc taggttcagg attaggtgaa ttagcagatg
    36241 aaatcgaaga tgctgtaatg atttcttatg atgagatccc gttctttcct gtttcgacag
    36301 tagttgggca tgcaggaaag ctagtttatg ggtctctggc aggcaagaaa gtgttagcca
    36361 tgcaagggag attccactac tatgaaggtc attccatgca aacagtgacc tatccagtac
    36421 gtgtgatggc cggactaggg gcccattcag tcattgtgac taatgcatgt ggtggtgtca
    36481 acgaatcatt tgtaccagga gatttgatgc tgattaccga tcatatcaat tttactggtg
    36541 aaaatccttt gatcggtccg aatgaagatg caatgggccc tagatttcca gatatgagtc
    36601 aagcttatac gcctgactat caagcaacag caaaagcagc agcagaaaaa ctaggtttgg
    36661 atcttaaaga aggcgtatat atgggctatt ctggaccaac ttatgaaacg cctgcggaga
    36721 tccgaatgtc tcggacaata ggagccgatg cagtagggat gtcgactgtt ccagaagtca
    36781 tcgtagcagc tcacagcgga ttaaaagtgt taggaatctc ttgtattacc aacttagcag
    36841 caggtatgca agcgaatctg agccatgaag aagttgtaga aacaactcag agagtcaaac
    36901 aatcttttaa agcattggtt aaagaaacat tgacattatt gtaataggag gaacaataaa
    36961 atgagtgtgc atattgaagc gaaagaaggc gagatcgccg ataagatttt acttccggga
    37021 gatcctttgc gagctaaata tattgcggag acttttttgg aagatccagt ttgttacaat
    37081 caggtacgcg gtatgttagg ctttaccggc aaatataaag gagaacgtat ttctgttcaa
    37141 ggaacaggaa tgggaatgcc atcagccacc atctatgccc atgaattgat ccagtcgtat
    37201 ggtgtaaaga aattgattcg agtaggtaca tgcggtgcat tgtcaaaaga cgtccatgtt
    37261 cgtgatttag tactagcaca aggtgcagcg accagttctt cgatgatcga aaaaaatttc
    37321 caagcctttc attttcctcc aatcagtgat ttcaatctat tactgaaagc atatgagata
    37381 gctaaagaaa agggctatac ggttcatgta ggaaatgttc tttcggaaga ttctttctac
    37441 aaagatgatt tgacagagac gttccaatta gctgaacttg gcgttttagg agtggaaatg
    37501 gaagcagcgg ctctttatta cttaggcgcg aaataccatg tgcagacatt aagtttgatg
    37561 accgttagcg accatttgat caccggtgaa gaaacaacag ctgcagaacg tcaatctacg
    37621 ttcaatgaaa tgatcgaagt aggattggaa acagcgatag cagaataaga aggaaatgaa
    37681 aaagctgccc tgcattaagt aataagaaca tccaagcaaa aatagctcct catgtttttg
    37741 acttggctgg acttattatt gcaaatgtaa gcttttgaac accgtttacc aagaggttgt
    37801 gaatctgccg tttaactctg agtcacaagg aacaatttca aaaaacagct tttcatgttt
    37861 gatgaatatt gtgacttgtg accgagaagt tggcaggaga aaaccgttta tacgaaaaaa
    37921 gggactgtga caaatcgtgt cacagtccct tttttatagt gttttttata ggtagtattt
    37981 tttagcaact gttaagtcat catttaattc ataaacaagt ggttgacctg ttggaatttc
    38041 aagatccatg atgtcttcgt cagagatacc ttcgatatgt ttagctaggg cgcgtaatga
    38101 gttaccatgt gcagctacta aaacagtttt gttgtctagt aatgctggag caatttcatc
    38161 ttgccagaat ggcaaagcgc gttctaatgt cactttcaag ttttctccac caggaatatc
    38221 gcgtttgtct aacattgcgt aacgacggtc atttgctgca gaaccttcgt cagtttcttc
    38281 cattaatgga ggaagagtat cgtaagaacg acgccagatg tgcacttgtt cgtcgccgta
    38341 tttttcagct gtttcttttt tgttcaaacc ttgtaattta ccatagtgac gttcgtttaa
    38401 gcgccatgat ttgatttgtg gtacccaaag ttgatctgaa tattctaaga tcaagttaca
    38461 tgttttgatt gcacgagtta aaacagaagt gtaagcaaca tcaaattcga ttccagcttc
    38521 tttgattttg cgtccgcctt cttttgcttc ttcgattcct tctggtgcta gatttacatc
    38581 agcccaacca gtaaattggt tcaatgcatt ccattcacta agaccgtgac gagaaaaaac
    38641 taattttggc atgtttagct ctccttttaa gataggttta tatttctgaa attttcagtt
    38701 ctgttttatt gtacaatttt ttggaagaga tttccatcga aaaattagat aagattctat
    38761 gagaaaacaa gtagagaata taaaaaaacg aacagtgccc acgcaactgt tcgtttttag
    38821 gtattagatg cataattgct cgatttcttt ttcaggtaaa ttgatatatt tataacatgt
    38881 tccaactgaa acaccgcatt ttgaagaaat aaattggatc gtttcttttt tttcataata
    38941 gagacgtcgg atttttttga tcgtttttgc atcgattttt ggtcttccgc cgatttttcc
    39001 ttttttacga gcttcatcta atccaactaa tgtacgttct ttgatcaatg cgcactccat
    39061 gtttgctagg ttttccatta attggaaata gatttttccc atttcgcgcg tatcgattcc
    39121 ttcatcaaga ctaatcaagt gcagcccgcg atctttgaat aattgcgtga gttctgttaa
    39181 ttgccgcgta gatttgccta atcgatgaag ttggcaaatg actagtgcat cgccttgttg
    39241 catgtcagcg atcactgact ccaaatgaac agcagtagaa tcattttgtt ccacttcata
    39301 tgtctcatgg aaaatttctt gacaaccaaa gtcagataat tgatcaacct gagttgttaa
    39361 atcaacgtca tttatggttg tgcgtgcata accaataatt ttcatggtga ttcctttcta
    39421 gcagtgattt tctaactgga tataacagta aaaatgtagc ataaagtacg tcaaaaagat
    39481 agttttttcg caaattttcc gctgtctttt tttattggat gatcaagcag tttttcttta
    39541 tttacgacgg attgcgtcaa gaatctcaac gcctttttct gagccgacaa ctactttaga
    39601 aaccatgttt aggaaaagcc catgttctac taccccaaca agttcatcta aataggtagc
    39661 taagctttct ggctgttcga tgacttctag atgcagatca atgatgtaat gaccaccatc
    39721 tgtggttaag acttctccgt tttcgtctgt acgcaagacg ggttggaatc ttttttcttc
    39781 aaaaatatga agtagctgtt gggagccata agggatcact tcaactggga gtgggaactt
    39841 cccaagttta tcgactaatt tagaagaatc aacgatccaa atcgtttctt ttgagtacgt
    39901 agcgactatt ttctcgaaaa gcaaagcagc gccgccgcct ttgatccctt gaaaatcagc
    39961 actgatttca tcagcaccgt ctattgtcaa atcgactacg gggacttcat caatactctt
    40021 taacggtatt cctaattttt ccgcttgttc ttttgtcgca tttgaagtag taactcctgt
    40081 gatacgtaaa ccttcttcac gcatacggcg accaatctct tctaccatat aataggcggt
    40141 tgaaccggtc ccgagaccta cgatcatccc gtcctttacg aatttcgcgg cttcaatgcc
    40201 agctaattgt tttaaattca tctttgcgtc cacctttttt tagtttgagc atcgtgcttt
    40261 cctcactatt ttagcgtgat ttacggtaaa aagataccat tcttttttat tccaataaag
    40321 ctttttcaaa aaaaattgca tctcttgttg acatgttttt tcattcgtga tattctaaca
    40381 aaggtgcttt atctacaggt ttctgtgaag aaacgtgctg actgtttatc aaagcatatt
    40441 tgataaggat gcagacattg catttatttt ttatcacaaa aaaagaacca cctggatgtg
    40501 tggaactaga cgcaaatcgt gggaaggagg aaacaaggaa tgcctacaat taaccaatta
    40561 gtacgtaaac ctcgtaaatc aaaggtggaa aaatctaatt cacctgcttt gaacaaagga
    40621 tataacagct ttaagaaaac tcaaactaac gtaaactcac ctcaaaaacg tggggtagca
    40681 actcgtgtgg gtacaatgac acctaaaaaa ccgaactcag ctttacgtaa atatgcacgt
    40741 gttcgtttgt caaacttaat tgaagttact gcttatatcc cagggattgg tcataactta
    40801 caagaacaca gtgttgtatt attacgcggt ggtcgtgtaa aagacttacc aggggtacgt
    40861 taccatatcg ttcgcggtgc tttagatact gctggtgtta acgaccgtaa acaaagccgt
    40921 tctaaatacg gaactaaaaa acctaaagct taattttaat tattaaacaa atgaaacttg
    40981 cttctactat atagaagtaa ttactatgaa caatatttcg gaaggaggag ttacggatgc
    41041 cacgtaaagg tcctgttgca aaacgtgatg ttttaccaga tcctatttat aactcaaaat
    41101 tagtaactcg cttgatcaac cgtgtaatgg ttgacggaaa acgcgggatt gcagctaaca
    41161 ttatctataa tgcctttgac ttgatcaaag aatctacagg taacgatcca ttagaagtgt
    41221 ttgaacaagc aatgaaaaac gttcaacctg ttcttgaagt taaagcacgt cgtgttgggg
    41281 gttcaaacta ccaagtacca gttgaagttc gccctgaacg ccgcgttact ctaggtcttc
    41341 gttgggtagt aaactacgct cgcttgcgcg gtgaacacac aatggaagaa cgcttagcaa
    41401 aagaaatcat ggatgctgca aacaacacag gtgcttctgt taaaaaacgt gaagacactc
    41461 ataaaatggc tgatgccaac cgtgcgtttg ctcactatcg ctggtaagat tctctctgtt
    41521 tggtcggctt ttataagtcg acctcagata gtgtccttat ttttagcaac tagatagtaa
    41581 agagaggaga aacaaggaga atgaccagag aattttcttt acaaaacact cgtaatatcg
    41641 gtatcatggc ccacatcgat gctggtaaaa cgactgctac tgaacgtatc ttgtactata
    41701 ctggtaaaat ccataaaatt ggtgaaactc atgaaggagc ttcacaaatg gactggatgg
    41761 aacaagaaca agaacgtggt attacgatca cttctgctgc tactacagca caatggaagg
    41821 gtcaccgaat caacatcatc gacacaccag gacacgtaga cttcacagtt gaagttgaac
    41881 gttcattgcg tgtacttgat ggtgctgtaa ctgttcttga tgcacaatca ggtgttgaac
    41941 ctcaaactga aacagtttgg cgtcaagcaa caacttatgg tgtacctcgt atcgtatttg
    42001 caaacaaaat ggacaagatc ggtgctgact tcttatattc agtatcaact ttacatgacc
    42061 gtttgcaagc aaacgctcac ccaatccaat taccaattgg tgcggaagac gacttcacag
    42121 gaattatcga ccttgtaaca atgaaggctg aaatgtatac aaacgatctt ggaacagaga
    42181 tcgaagaaac agaaattcct gaagaatacc gcgaattagc tgaagaatgg cgcgaaaaat
    42241 tggttgaagc tgtagctgaa actgatgaag aacttacttt gaaatactta gaaggtgaag
    42301 aaatcactga agctgagtta aaagaaggta tccgccgcgc aacagttaac gtagaattct
    42361 acccagtact atgtggttca gcatttaaga acaaaggggt tcaattacta ttggacgctg
    42421 ttcttgatta cttgccatca ccgttagata tcccagctat caaagggatt gaccctaaaa
    42481 ctgatgaaga agtagaacgt cctgcagacg acagcgctcc tttctcagct ttagcattta
    42541 aagttatgac tgacccattc gtaggtcgtt taactttctt ccgtgtgtac tctggtgttt
    42601 tacaatcagg ttcatacgta caaaacgcaa caaaaggcaa acgtgaacgt gttggtcgta
    42661 tcctacagat gcatgccaac tctcgttcag aaatctctga agtttacgct ggagatatcg
    42721 ctgctgctgt tggtttgaaa gacacaacta ctggggacac actatgtgat gaaaagagtc
    42781 tagttattct tgaatccatg gaattcccag aaccagttat ccaagtcgct attgaaccta
    42841 aatcaaaagc tgaccaagat aaaatgggtg tggctttaca aaaactatct gaagaagatc
    42901 ctactttccg tgctgaaaca aacgtggaaa caggcgaaac aatcatcgct ggtatgggtg
    42961 aacttcactt agatatcatc gttgaccgta tgcgtcgtga attcaaagtt gaagctaacg
    43021 taggtgcgcc tcaagtatct taccgtgaaa ctttccgtgc tggcactcaa gccgaaggta
    43081 agtttgtacg tcagtctggt ggtaaaggtc aatacggtca cgtatggatt gaatttacac
    43141 caaatgaaga aggtgctggt ttcgaatttg aaaatgcgat cgtcggtggg gttgttcctc
    43201 gtgaatacat tccagctgtt gaaactggtt tgaaagatgc tatggaaaat ggtgtcttag
    43261 ctggctatcc attagtagat atcaaagcta aactttacga tggttcatac catgatgtcg
    43321 attcaaatga aactgccttc cgtgttgctg cttctatggc attacgtgca gcagctaaga
    43381 aagctaatcc agtaatcctt gaaccaatca tggctgtaga agttgttatc cctgaagatt
    43441 atttaggtga tgttatgggt cacgtaactg ctcgtcgtgg acgtgttgaa ggtatggaag
    43501 ctcgcgctgg cggccaacaa gttgttcgtg cgatggttcc acttgctgaa atgtttggtt
    43561 atgctacaac tcttcgttct gctactcaag gtcgtggtac atttacaatg acatttgacc
    43621 actacgaaga tgtaccaaaa tcagtacaag aagaaatcat taagaaaaac ggcggaaaag
    43681 ctgaataatt tcttgaaacc ggatagtcct gcaaagagat tatccaaaga gactatattt
    43741 ttaatatagt ttcgtgtaaa ataattatcg atgatatggg catgtggtgt accttgtgta
    43801 catcatatac ctatcagaca aataaaaaat atattgtatt tttaggagga cattttaaaa
    43861 tggcaaaaga aaaatttgac cgttctaaac cacacgttaa cattggtact atcggacacg
    43921 ttgaccatgg taaaactaca ttaacagctg caatcacaac tgtactatct aagaaaaacg
    43981 gcggccaagc tatggcttac gatcaaatcg atggtgctcc agaagaacgc gaacgcggaa
    44041 tcacaatctc aacagctcac gttgagtatg aaacagatac acgccactac gctcacgttg
    44101 actgcccagg acacgcggat tacgttaaaa acatgatcac tggtgctgct caaatggacg
    44161 gagctatctt ggtagtttct gctgctgacg gcccaatgcc tcaaactcgt gaacacatcc
    44221 tattgtctcg tcaagttggt gttccttaca tcgttgtatt cttgaacaaa gtagacatgg
    44281 ttgatgacga agaattacta gaattagttg aaatggaagt tcgtgaccta ttaacagaat
    44341 acgaattccc tggtgacgat gttcctgtag ttgctggatc agctttgaaa gctctagaag
    44401 gcgacgcttc atacgaagaa aaaattcttg aattaatggc tgcagttgac gaatacatcc
    44461 caactccaga acgtgacaac gacaaaccat tcatgatgcc agttgaagac gtgttctcaa
    44521 ttactggacg tggtactgtt gctacaggtc gtgttgaacg tggacaagtt cgcgttggtg
    44581 acgaagttga agttgttggt attgctgaag aaacttcaaa aacaacagtt actggtgttg
    44641 aaatgttccg taaattgtta gactacgctg aagctggaga caacattggt gctttactac
    44701 gtggtgttgc acgtgaagac atccaacgtg gacaagtttt agctaaacca ggtacaatca
    44761 cacctcatac aaaattctct gcagaagtat acgtgttgac aaaagaagaa ggtggacgtc
    44821 atactccatt cttcactaac taccgtccac aattctactt ccgtacaact gacgtaacag
    44881 gtgttgttga attaccagaa ggaactgaaa tggttatgcc tggcgacaac gtaacaatgg
    44941 aagttgaatt aatccaccca atcgctatcg aaaacggtac taaattctca atccgtgaag
    45001 gcggacgtac agttggtgcc ggtgtcgtta cagaaatcaa agcttaattc acttaagttt
    45061 taaagtaaag caacatttat tcggacgtaa tcgctcggaa cgaaggtctt aggatctttg
    45121 ttccgagctt ttttatttat tgcaggatca ggaaaaaaga caggagtatt ataaatagaa
    45181 gaaacacgaa ataaaagagt cagtattttc taaatgaaac tttatgaaaa caaaatgttt
    45241 tttacaagaa aaagccttgc tttgtgagtt tatatatatt ataatgacaa aggtgcgttt
    45301 actttagtga attgcacaga cgtaatcaga atgatttcgt cggctaagaa acgagaggtt
    45361 gcgacacgcc cggacgcttt gccacgaacg agcgtgacgg aaattttcgt ggagctatgt
    45421 ctacttttca aaataggcga aggagggaac aagatggcaa aacaaaaaat tcgtatccgt
    45481 ttaaaagcgt atgaacaccg tattttagat caatcagcgg ataaaatcgt ggaaactgca
    45541 aaaagaactg gagctagcgt gtctggtcca attccattac caactgaacg cagtctttac
    45601 acaatcatcc gtgcgactca taaatacaaa gattcacgcg aacaattcga aatgcgtaca
    45661 cacaaacgtc ttatcgacat tgtgaaccca acaccaaaaa ctgttgatgc tttgatgaag
    45721 ctagacttac catctggtgt aaacatcgaa atcaaattat aaaactaaaa caaaaataat
    45781 ggaggtgtac tcatgaccaa aggaatctta gggaaaaaag tgggaatgac acaaatcttc
    45841 actgaatctg gtgaattaat tccagtaact gttgtagaag ctactccaaa cgtagtacta
    45901 caagtgaaaa caatggaaac ggatggctac gaagctattc aagttggtta ccaagatatg
    45961 cgtgaagttt tatcaaacaa acctgcgaaa ggtcatgttg caaaagcaaa cacggctcct
    46021 aagcgcttca ttcgtgaatt caaaaatgtt gagctaggag aatatgaagt aggaaaagaa
    46081 attacagtag atgttttcca agcaggagac attattgatg taacaggtac tacgaaaggt
    46141 aaaggattcc aaggggttat caaacgccac ggacaaagcc gcggaccaat ggctcacggt
    46201 tctcgttacc atcgtcgtcc tgggtcaatg ggtccagttg cacctaaccg tgtatttaaa
    46261 aacaaacgtc ttgctggccg tatgggtggc aaccgcgtaa ctatccaaaa cttggaagtt
    46321 gtacgtgtcg atgcagaaag aaatgttatc ttgatcaaag gtaatgttcc tggagctaaa
    46381 aaatctttaa ttactatcaa atcagctgtg aaagctaaat aattgtagga agaaaggagg
    46441 aactaaggaa tgccgaatgt agcattattc aaacaagatg gaagccaaaa cggtgaaatc
    46501 acacttaacg aagaaatctt cggaattgaa cctaatgaaa gtgttgttta cgatgcaatc
    46561 gtaatgcaac gtgcgtcatt aagacaagga acacacgcgg ttaaaaaccg tagcgctgtt
    46621 cgcggcggcg gacgtaaacc atggcgtcaa aaaggaacag gtcgtgcacg tcaaggatct
    46681 atccgctcac cacaatggcg tggaggtggc gtagtctttg gaccaacacc acgttcttac
    46741 agctacaaac ttcctaaaaa agttcgtcgt ttagcaatga aatctgtatt gtcagaaaaa
    46801 gttgctgaaa acaacttggt agcaatcgaa ggcttgaact tcgacgcacc aaaaacaaaa
    46861 gaattcaaac aagttcttgc taacttatct atcgactcta aagtattggt tgttctagaa
    46921 aaaggtaacg actttgctgc tttatcagca cgtaacttac caaacgtttc tgtagtaact
    46981 tctgataatg tgagtgtgct agacgttgta tcaaatacaa aagtgttagc aacacaaact
    47041 gctcttactc aaattgagga ggtgcttgca taatgaactt actagacgta atcaaacgcc
    47101 cagtgatcac tgaaaaatca atgcttgcca tggatgacaa gaaatacact tttgaagtgg
    47161 acactcgcgc aaacaaaact ttagtaaaac aagcggtaga agctgctttt gacgttaaag
    47221 tcaaaaacgt gaacatcgtg aacgtacgtg cgaaattcaa acgtatgggc aaatatgcag
    47281 gatatacaaa aaaacgtcgc aaagcgatcg ttacattgac tgaagattca aaagaaatcc
    47341 aattattcga agctgctgaa taagcactaa tagataactc attaaattag gagggaaaaa
    47401 cgtggcgatt aaaaagtaca aacctacctc aaatggtcgt cgtaacatga caggttctga
    47461 ttttgctgaa atcacaacat caacacctga aaaatcattg ttacaaccat tgaaaaacca
    47521 tgctggacgt aacaacaacg gccgcatcac tgtacgtcat caaggtggcg gacacaaacg
    47581 ccaatatcgc gtgatcgact tcaaacgtaa caaagataac gttgttgcaa ctgttcaaac
    47641 gatcgaatat gatccaaacc gttcagctaa catcgcgtta gtacactatg aagatggagt
    47701 gaaagcttac atcttagcac ctaaaggact agaagtgggt atgaaacttg tttcaggtcc
    47761 agaagcagat atcaaagtcg gaaatgctct tccattagaa aacattccag ttggtactgt
    47821 tatccacaac attgaaatga aacctggtaa aggtggacaa ttgatccgtt ctgctggtac
    47881 aagtgctcaa gtacttggta aagaaggcaa atacgtattg atccgcttga actctggtga
    47941 agttcgtatg atcttagctg catgccgtgc tacaatcggt tctgtaggta acgaacaaca
    48001 cgaattaatc aacatcggta aagctggacg ctctcgttgg atgcgtaaac gcccaactgt
    48061 acgtggtagc gtaatgaacc ctaatgatca cccacacggt ggtggtgaag gtaaagctcc
    48121 tatcggacgt aaagcaccag tttctccttg gggtcaacca gctcttggtt acaaaactcg
    48181 taacaaaaaa gctaaatcag acaaacttat tgttcgtcgt cgcaaaaata aataattact
    48241 ttgaccatgt gtcgcacatt ttgagaggag gttcaccatg ggtcgtagtt taaagaaagg
    48301 accttttgtc gatgagcatt taatgaaaaa agttgaagct caagcagggg ttgaaaagaa
    48361 aaaagttatc aaaacttggt cacgccgttc aacagttttc ccaagttttg ttggatatac
    48421 catcgcagtt tatgatggac gtaaacatgt accagtttac atccaagaag acatggtagg
    48481 acacaaatta ggtgaatttg cacctacaag aacttatcgt ggacatgctg ctgacgataa
    48541 gaaaacgaaa cgctaatttg aggggaggat aaatccaaat ggcagaacaa atcacatcag
    48601 ctaaagcaac tgcaaaaaca gttcgcactt cacctcgaaa agcccgttta gtaattgacc
    48661 ttatcagagg taaaagtgtc gcagatgcaa tttcaatctt gaaattcaca ccaaacaaat
    48721 ctgctggaat cattgaaaaa gtattgatgt cagcagttgc gaatgcagaa aataactttg
    48781 acttagatgt tgaaaacttg gtagtaagcg aagcttttgt taacgaagga cctacaatga
    48841 aacgtttccg tcctcgtgca aaaggatcag cttctccaat caacaaacgt acaagtcata
    48901 tcacggtagt cgtatcagaa aaataaggag ggataatcag tgggtcaaaa agtacatcca
    48961 attggaatgc gtgtaggcat catccgcgac tgggatgcta aatggtatgc tgaaaaagag
    49021 tatgctgagt tcttacacga agatttaaga atccgtaaat ttatttcaac taaacttgct
    49081 gatgctgctg tatcaacagt tgaaatcgaa cgcgcaacag gtcgcgtaaa catttcaatt
    49141 cacacagcta aaccaggtat ggttattggt aaaggcggtt ctgaagtcga aagcctaaga
    49201 aaagaattaa acaaattaac tggtaaaaga atccatatca atatcgtgga aatcaaaaaa
    49261 ccagatctag atgcaaaatt agtaggtgaa ggaatcgcac gtcaattaga aaaccgtgtt
    49321 gctttccgtc gcgctcaaaa acaagccatc caacgctcaa tgcgtgctgg cgctcaaggg
    49381 atcaaaactc aagtatctgg tcgtctaaac ggagcagata tcgctcgttc agaaggatac
    49441 tcagaaggaa ctgttcctct tcatacttta cgtgcggaca ttgattacgc atgggaagaa
    49501 gcagatacaa catacggaaa actaggagtt aaagtgtgga tctatcgtgg agaaattctt
    49561 ccaactaaaa aaaacactga gaaaggaggg aaataatcat gttagtacct aaacgtgtaa
    49621 aacaccgtcg tgaattccgc ggaaaaatgc gcggggaagc taaaggcgga aaagaagtag
    49681 cattcggtga atacggtttg caagctgttg attcacattg gatcacaaac cgccaaatcg
    49741 aagctgctcg tatcgcaatg actcgttaca tgaaacgtgg tgggaaagta tggattaaaa
    49801 ttttccctca caaatcttat actgccaaag caattggggt acgtatgggt tctggtaaag
    49861 gggcacctga aggatgggtt gcaccagtaa aacgtggtaa aatcatgttt gaaatcgcag
    49921 gcgttcctga agaagtagct cgtgaagcgt tacgtctagc ttctcacaaa ttaccaatga
    49981 aaactaagat cgtaaaacgt gaggaaatgg gtggtgaatc gaatgaaggt taaagaaatc
    50041 agagaattaa ccactgccga aatgcttgat caagaaaaac aattaaaaga agaattgttt
    50101 aatcttagat tccaattagc aacaggtcaa ttagaaaaca ctgcacgtat taaagaagta
    50161 cgtaaatcga ttgcacgcat caaaactgtg ttgcgtgaac aagctaagta attatggaag
    50221 gaggccatta agcgtatgac tgaaggaaga aatcaacgca aagtttatca aggtcgcgtg
    50281 gtttcagaca aaatggataa aacaattacc gttgctgtcg aaacaaagaa aaaccaccct
    50341 atctatggca aacgcatgaa ctattctaag aaatacaaag tgcatgatga aaacaacaca
    50401 gcaaaagttg gcgacatcgt gagaattatg gaaactcgtc cattatcagc tacaaaacgt
    50461 ttccgtttgt tggaagtagt cgaagaagca gttattatct aataacacga gattttccta
    50521 tatagattga atgcaaaatc tgaaaggagg atacacaacg tgatccaagc agaaagtcgt
    50581 ttaaaagtcg ctgataactc aggcgcacgt gaaattttga cgatcaaagt ccttggtgga
    50641 tctggtcgta aaactgctaa catcggtgat gtgatcgttg ctacggttaa acaagcaacg
    50701 ccaggtgggg ttgtcaaaaa aggtgacgtc gttaaagccg ttatcgttcg aacaaaatca
    50761 ggagctcgtc gtacagacgg ttcatatatt aaatttgatg aaaatgctgc agtgattatt
    50821 cgtgatgata aaagccctcg tggaacacgt atctttgggc cagttgcacg tgaactacgt
    50881 gaaaacaact tcatgaagat cgtttcacta gcaccagaag ttttataatc ttgagacact
    50941 tatcaaagga ggtgcgaaac agttatgttt gttaaaaaag gcgataaagt taaagttatc
    51001 actggaaaag acaaaaacaa agaaggcgtt gtactagcag cgttcccgaa aaaagataaa
    51061 gttattgtcg aaggtgtaaa tgtcgttaaa aaacaccaaa aaccttctca agctgctcct
    51121 caaggtggaa ttgttgagat ggaagcgcca attcatgttt ctaacgtgat ggtggttgac
    51181 tctactggtg tagctggccg agttggctac aaagaagtag acggcaaaaa agtccgtgtt
    51241 tctaaaaaaa ccggtgaagt tttagataaa taaaagttta aggaaggagg gtcttactga
    51301 atgaaccgcc taaaagaaaa atatcttaaa gaagtaactc catcattgat ggaaaaattt
    51361 aactatagct ctgttatgca aacacctaaa gttgaaaaaa tcgtcatcaa catgggtgtt
    51421 ggtgatgcgg tatcaaacgc taaaaactta gataaagcag ttgaagaatt aactttgatc
    51481 actggtcaaa aaccaatgat tacaaaagct aaaaaatcaa tcgctggatt ccgtttacgt
    51541 gaaggaatgc caattggtgc aaaagttaca ttgcgcggag aaagaatgta cgaattctta
    51601 gacaaattgg tttctgtttc actaccacgt gtacgtgact tccatggtgt aagtaaaaaa
    51661 gcctttgacg gtcgtggaaa ctatacttta ggtattaaag aacaattgat cttcccagaa
    51721 gtagattatg atttagtaga taaagtacgt ggtatggaca tcgttattgt aacaacagca
    51781 aactctgatg aagaatctcg tgagttgttg acacaattag gcatgccatt ccaaaaataa
    51841 ttaaaggagg cgaactacgt ggctaaaaaa tcaatgattg ctaaaaacaa acgtcctgca
    51901 aaattttcaa cacaagctta tactcgttgc gaacgttgcg gacgtccaca ttcagtttat
    51961 cgtaagttcc atctttgccg tatttgcttc cgcgaacttg cctataaagg tcaaattccc
    52021 ggcgtgaaga aagctagctg gtaaaaagta aattcgcata agaaggaggt aaaagatcaa
    52081 tggtcatgac agatccaatt gcagattttc taactcgtat ccgtaacgca aacatggtta
    52141 aacatgagtc tttagaagta cctgcatcaa aaattaaacg tgacatcgct gaaatcttga
    52201 aacgtgaagg tttcgttcgt gatgttgaat acatcgaaga tgacaaacaa ggcgtgatcc
    52261 gtgttttcct aaaatttggt aaaaacggcg aacgtgttat cacaaactta aaacgtatct
    52321 ctaaaccagg tttgcgtgct tatgtcaaag ctgacgaagt accaaaagta ttgaacggtt
    52381 taggtatcgc aatcatttcg acttctgaag gtgttgtcac tgataaagaa gctcgtgaaa
    52441 aaaatatcgg cggcgaagtt atcgcttacg tatggtaatc aagtagaatc tacaaggagg
    52501 tgtctttaag tgagccgtat cggaaataaa gtcgttgtta tccctgaagg agtaacagtt
    52561 actcaagacg gaaacaacgt tacagttaaa ggaccaaaag gtgaattgac tcgtactttt
    52621 tcagcagata tcaaaatgaa tatcgaagga aacgaagtaa ctttcactcg tccaaacgac
    52681 agtaaagaaa tgaaaacaat tcatggaaca actcgtgcga acttcaacaa catggttgta
    52741 ggtgtcagcg aaggtttcca aaaagcgtta gaactaatcg gggttgggta ccgtgcacaa
    52801 ttacaaggat caaaacttgt attgaacgtt ggttactcac atccagtaga aatcacacca
    52861 ccagctggag taactgttga agtaccagct aacacacaag taattgttaa aggtgcgaac
    52921 aaagaagaag ttggcgaatt agctgcaaac attcgtggaa ctcgtcctcc agaaccttat
    52981 aaaggtaaag gtattcgtta tgttggcgaa tatgtacgcc gtaaagaagg taaaactggt
    53041 aaataatcgt ttagaaaaat tgcatagaag ccagcagcag gaaaaaggca tttggctgaa
    53101 gtttaccttc aaaaaaatac atttttactt gtgccgcagc ttctattttt cgaaacgtat
    53161 ttactgcttg aaatagtagt acaataaaaa taaagaggtg acaattgtga ttacaaaacc
    53221 agataagaac aaaacacgtc aaaagagaca tcgtcgtgta cgtaacaata tctctggtac
    53281 tgctgagcgc ccacgcttga acgtttttcg ttctaacaaa aacatctacg ctcaaattat
    53341 tgatgacgta gcgggtgtaa cgctagcaag tgcctctacc ttggataaag aaatttcagg
    53401 tggaacaaaa acagaagcag cacaagctgt cggtaaacta gttgctgaac gtgcagctga
    53461 aaaaggcatt aaagtagtag tctttgaccg tggtggatac ctttaccatg gccgtgtgca
    53521 agctttagct gaagctgctc gcgaaaatgg actagaattt tagaagaagg aggaatacca
    53581 ttcatggttt atatcgatcc aaaacatttg gaattagaag accgcgttgt tgcaattaac
    53641 cgtgtaacaa aagttgttaa aggtggacgt cgtctacgtt ttgctgcttt agttgttgtc
    53701 ggtgacaaaa acggacacgt agggtttggt acaggtaaag ctcaagaagt tcctgaagca
    53761 atccgtaaag caattgaaga tgcgaagaaa aacttagttg aagtacctat ggttggttca
    53821 acaatcccac acgaagtaat cggtgctttt agtggtggta gaatcctaat gaaacctgct
    53881 gtagaaggtt ctggggttgc tgctggtgga ccagttcgtg ccgtattaga attagctggg
    53941 gtagcagata tcacttctaa atctttaggc tcaaatacac caatcaacgt tgttcgcgca
    54001 acagttgaag gtttgaaaca attgaaacgt gcagaagaag ttgcagaact tcgcggcaaa
    54061 tcagttgaag aattaatcgg ataaggagga caacaataat ggctgaatta aaagttactt
    54121 taaaacgcag tattatcgga cgtcctcaaa accaacgcga tacagttaaa gcgttaggtc
    54181 ttacaaagat taacagttca gtggttaagc cttctaatga agcaattaaa ggcatgatca
    54241 atactgtttc tcacctagtg gacgttgaag aaatttaatt tagaaaaatc ataactagaa
    54301 cattaaggag gtgccaaacc tatgaaactt catgaattaa aacctgctga aggttcacgc
    54361 caagtacgta accgtgttgg tcgtggtact tcatctggta acggaaaaac tgccggacgc
    54421 ggacaaaaag gacaaaaagc tcgttcaggc ggcggtgtgc gtttaggatt tgaaggggga
    54481 caaacaccat tgttccgtcg tttaccaaaa cgaggattca caaacgtgaa ccgtaaagac
    54541 tatgcagtca ttaatcttga tgtattgaac cgctttgaag acggagctga agtaactcct
    54601 gttgctttag ttgaagctgg aatcgtgaaa aacgaaaaag ctggaatcaa agtattagct
    54661 aatggggaac taaacaagaa attaactgtg aaagcagcaa aattctctaa agcagctcaa
    54721 gaagcaattg aagcggctgg tggatcaatc gaggtgatct aatgtttaga ctattaaaag
    54781 atgcttttaa agtaaaagac attagatcga aaatcctatt tactgtattt gtgttgtttg
    54841 tatttcgcct aggtgcacat attactgtac caggcgtaaa tgctgcttca ttgcaaaacc
    54901 tttcttcttt gccatttttc aacatgttga acttggtaag tggtagtgcg atgcaaaact
    54961 tttccatttt ctcaatgggg gtttcaccat acattactgc ttctatcgtc attcagcttc
    55021 ttcaaatgga catcgtgcct cgatttgttg aatggtcgaa acaaggggaa gttggtcgta
    55081 aaaaactgaa tcaagcgact cgatatctga cattagtatt ggcatttatc caatctgtcg
    55141 gtatcactgc tggattcaat caatacgctc aattaggttt cgtgaataat cctaacgtag
    55201 caacttacgt aacgatcggt ttgattctaa cagccggtac gatgtttgtt acttggctag
    55261 gagaacagat cacagaaaaa ggtatcggaa atggcgtatc aatgatcatt tttgcaggta
    55321 tcatttctag attgcctgaa agtatcagag aaatttatga agattacttt ataaatattg
    55381 atccttcaga catatggaaa tctgctattt ttgtggccat tttactagta gcggtcttgt
    55441 tgatcgtgac attcgtaaca tttttccaac aagctgaacg caagatcccg atccaatata
    55501 cgaaacgcgt agctggcgcg cctacaagca gctatctgcc gttgaaagta aatgcagctg
    55561 gagttattcc agttatcttt gctagttcgt ttattgctac gccaaatgct gttttacaag
    55621 cattgagcgg tagattcggt tctgaaaact ggtacaaagt gatgatggag atctttaact
    55681 ataatacagc acctggtgct acgatttata cgattctgat cgttgccttc actttcttct
    55741 acgcctttgt tcaagtaaac cctgagaaat tagcggaaaa cttgcaaaag caaggaagtt
    55801 atataccaag cgtacgccct ggtaagggga ctgaagagta tgtctcaaga ttactgatgc
    55861 gtttaagtac agttggtgca gtcttccttg gtttagtggc attgcttcca atcattgctc
    55921 aaatggtttg ggatcttcca caatcaatcg gattaggcgg tacaagctta ctgatcgtta
    55981 tcggtgtagc tttagaaact gcgaaacagt tagaaggctt aatgctgaaa cgtaaatatg
    56041 ttggattcat tgagtaagaa agcgtgttga ggtttcccct caacacacgt tctcacacat
    56101 ttattaggag ggaaaacaat gaacctcatt ttaatggggc tgccaggcgc aggtaaagga
    56161 acacaagctg aaaaaatcat tgatgcttat ggtattccgc acatctcaac aggagatatg
    56221 ttccgcgcag cgatgcaaaa cgaaacagct cttggcctgg aagcaaagtc ttatatggat
    56281 aaaggtgcat tagttcctga tgaagtaaca aatggaatcg tgaaagagcg actagctgaa
    56341 ccagatacag agaaaggctt cttattagat ggctttccac gtacgctaga tcaagcaaaa
    56401 gctctggacg caatgctaaa agatttgaat aaaaaaattg atgctgtcat cgatatccat
    56461 gttggtgaag aaatcttggt cgaacgtcta gccggccgat ttatctgcag caattgtgga
    56521 gcaacttacc ataaaatttt caaccctaca aaagttgaag acacatgtga tcgttgcggt
    56581 gggcatgaat tctatcaaag agaagatgat aaacctgaga cggttaaaaa tcgtctggct
    56641 atcaacatca aaaatagtga accaatcttg gcttattata aagaacaagg tttgctaaac
    56701 actattgatg gtgctcgtga aatcgatgct gtatttgcag atgtacaaaa aatcattgaa
    56761 aaatagcacg attgcccgta gccgacttgc attatgcagt tactcttgtc aagttcaata
    56821 aattatgata gaatatgtca gtccgacttc tagagaatcc tctagatgat ccattttgag
    56881 aattttgagg tgggaactgc agtttccgcc attttatcgt gtgaaaatgc gaaacaagta
    56941 caaggaggta ctgtgcgtgg caaaagaaga tatgattgaa gtcgaaggta cagtcgtcga
    57001 aactttgccg aatgcaatgt ttaaagttga actagaaaac ggacaccaag ttcttgctac
    57061 tgtttcaggt aaaattcgta tgcattacat ccgtatctta cctggtgaca aagtaacggt
    57121 tgaattgtct ccatacgatc ttaaccgtgg ccgtattact tatcgcttta aataattgta
    57181 ctccgtaaaa ctacaggagg tattatcatg aaagtaagac catcagtaaa accaatgtgc
    57241 gaacattgta aagtaattcg tcgtaaagga cgcgttatgg tgatttgccc agcaaatcca
    57301 aaacataaac aacgtcaagg ataattggag gtgctataaa tatggctcgt attgcaggag
    57361 tagatattcc tcgtgataaa cgtgtagtag tttcacttac ttatatctat ggtattggta
    57421 acactactgc taaaaagatc ttagctgatg ctggtgtatc tgaagatgtt cgcgttcgtg
    57481 aattaacgaa tgaacaaaca gatgctatcc gtgcagaagt agataaatta aaagttgaag
    57541 gggatcttcg tcgtgaagtg aacttgaaca tcaaacgttt gatggaaatc ggttcttacc
    57601 gtggaatccg tcatcgccgt ggattgcctg ttcgtggaca aaacacgaaa aacaatgcac
    57661 gtactcgtaa aggcccagct cgcgctatcg ctggcaagaa aaaataattc ttaagtgaag
    57721 gaggttaaaa cttcatggca gcaaaaaaag tgaatcgtaa acgccgtgtg aagaagaata
    57781 tagaagcagg tattgcacat atccattcta cattcaataa cactatcatc atgatcactg
    57841 atactcacgg aaatgcatta gcgtggtcat cagctggttc attaggtttc aaaggaagca
    57901 aaaaatcaac tccttttgcc gctcaaatgg cagcagaaac tgctacaaaa gcagcaatgg
    57961 aacacggatt aaagactgtt gaagtaacag ttaaaggacc tggttctgga cgtgaagcag
    58021 caattcgttc attacaagct acaggtttag aagtgactgc aattcgtgac gtgactccag
    58081 ttcctcataa tggtgcccgc cctccaaaac gccgtcgtgt ttaatgagtg ccgctcattt
    58141 tgagttttat cagtaacgtc attgaacaag acacttttcg ttttgaaagg ggtaaagata
    58201 agaatgattg agttcgaaaa accaagaatc gcaaaaattg atgaagaaaa agattatggc
    58261 aagttcatcg ttgaacctct tgaaagaggg tatgggacta ctttagggaa ttccctacgt
    58321 cgtattttat tatcttcttt gccaggtgct gccatcacta atattcaaat cgatggtgta
    58381 ctgcatgaat tctctaccat caaaggtgtt agagaagacg tcactcaaat catcttgaac
    58441 attaaaggct tagcgctgaa aatgtatggc caagaagaaa aaacccttga aatcgatatt
    58501 accggacctg ctacagtaac tgctggcgat attatcgttg atagtgatgt agaaattctt
    58561 aacaaagata tgtacatctg tagtgtctct gaaggagcta cgttccatgc tcgcttaaca
    58621 gtgaaacctg gacgtggtta tgttcaagca gatgaaaata aaaaagaaga tatgccaatt
    58681 ggcgttcttc cagtcgattc aatctacaca cctgttcgtc gtgtgaacta tcaagttgag
    58741 aacacacgtg ttggacaccg tgaagatttt gataaattga cgatggagat ttggacagat
    58801 ggttcaattg aaccgttgga agcaatgagt ttgtctgcga aaatcatgac tgaacatttg
    58861 gatatttttg tgaacttaac tgatgaagca aaaaatgctg aaatcatggt cgaaaaagaa
    58921 gaaacacaaa aagaaaaaat gttggaaatg acgatcgaag agttagactt gtctgttcgc
    58981 tcttacaatt gtttgaaacg tgcaggaatc aatactgtac aagaacttac aaataaatct
    59041 gagcctgaaa tgatcaaagt ccgtaactta ggacgtaaat cattagaaga agttaaagca
    59101 aaattgcacg acttaggttt aggtttacgt aaagaagatt aaaacctttt acgaaggagg
    59161 gaaaccaacg tgagttatcg taaactagga cgcacatcta gccaacgtaa agcgatgttg
    59221 cgtgatttaa caactgattt attaatcaac gaacgtattg tgactactga agctcgtgcg
    59281 aaagaagttc gctcaactgc agaaaaaatg atcactttag gtaaacgcgg agatttgcat
    59341 gcacgtcgtc aagctgcggc tttcgtacgt aatgaagttg ccagcgtgcg tgaagaaaat
    59401 gaggacatcg tcattgaatc agctttacaa aaactgttca acgatattgc acctcgttac
    59461 gcagaacgtc aaggcggata cacacgcatt ttgaagacag aaccaagacg cggtgatggt
    59521 gcaccaatgg ttgtcttaga acttgtctaa aatcacacta ataacatcac tttatagatg
    59581 attcttttag agtgttatga tgttggaaga tatttttccg agtctagctc agcgctgctc
    59641 ctcaagcgaa tatcgcttgg ggagtaagca ctcatcataa agtgtttttt tataccttca
    59701 attacctgtc atgacagata tgtttgaagg cataaaaaaa cattttaagc gagaaataat
    59761 tgaaaatttt gtcttttttt gatagtgtta gtaggaactt taggatgaag aaggagtaat
    59821 catggagcca attattgaat tagaaaagat aaattataaa taccagccag atgatcttcg
    59881 ccccgcattg aaagatgtct cctttacaat tgataaaggt gagtggatcg ctattattgg
    59941 acacaatggt tcaggaaaat cgacacttgc caaaacgatc aatggattgc ttctgccaga
    60001 atcagggatc gtgaaagtgg gaaatcaaat attggatgaa gaaaatattt ggacgatccg
    60061 acagatggtt ggaatggttt ttcaaaatcc agacaatcag tttgttggtt cgacagtaga
    60121 agatgacgtt gcttttggtc ttgaaaatca agggattccc agagaagaaa tgctagtgcg
    60181 tgtgaaagat gcacttgaga aagttagaat ggctgagttt gcttcacgcg agcctgctcg
    60241 tttatcagga gggcaaaaac aacgtgttgc cattgccggc gtggttgcct tacgacctga
    60301 tatcattatt ttagatgaag caaccagtat gctagatcca gaaggtcgtg aagaagtgat
    60361 ctctacgatc aagaagatca aagaagaaag tcaattgacc gttatatcta tcactcatga
    60421 tattgatgaa gcagctaatg ccaatcggat actagtgatg agacaaggcg aacttgtccg
    60481 tgaaggtaca ccaaaagaaa ttttttctgc tggtcctgaa ctgatcgact taggtctaga
    60541 tctaccattt cctgaaaaac tgaagagcgc actgaaagaa cgtggggttg atgtgcccag
    60601 tgaatatatg acagaagaaa ggatggtgga ttggttatgg acatccgttt tgaacaagta
    60661 gacttcactt atcagccgaa tacaccattt gaacaaagag ccttatttga catcaatatg
    60721 acgatcaaag aaaacagtta tactgcatta gtagggcata ccggaagcgg gaaatcaacc
    60781 ttacttcagc atttgaatgc gcttgttaag ccaacaagcg gtacagtcca tattggagaa
    60841 cgagatattc agccggatac ggataataag aatttaaagc ccatccgaaa aaaagttggc
    60901 atcgtctttc agtttccaga agcacagcta ttcgaagaaa cggtagcaaa agacattgct
    60961 ttcggtccta aaaactttgg tgtcagcgaa gaagaagcac tagtcctagc aaaagaaaca
    61021 ttagaacaag ttgggctgga tgaaagctat ttggaacgtt cgccatttga actttcagga
    61081 gggcaaatgc gtagagtagc aatcgctggt gtgcttgcca tgaggccgga agtacttgta
    61141 ttggatgaac caacggcagg acttgatccc cagggtagaa aagaaatgat ggagatgttt
    61201 tggcgtcttc ataaggaaca gcagatcact attgtattag ttacgcattt aatggatgat
    61261 gtagccaatt ttgcagatta tgtctatgtg ttggaaaagg gacgaatcgt taatagcggg
    61321 gagccgcaag aggtctttca aaacattgaa tggctaaaag aaaaacaact aggcgtacct
    61381 actgccaccg agtttgcaga agaattaatg gctaaaggga tgaactttgc taccttgcct
    61441 ttgacagctg aagaattagc agacgctatc gtccattatg ctggaggaaa tgcccatgat
    61501 gaataaattg atatttggtc gttatatgcc tggagattcc ttgatccatc gattggatcc
    61561 ccgagctaaa ttattagcca gtttttattt tatcggaatc atttttttag caaataattg
    61621 ggaaacgtac cttttgttgg catttttcac attactttct gtcttcttgt caaaagtaga
    61681 tttgaaattt tttatccgag gcattcgccc attgatctgg ctaatcctct tcactgtagc
    61741 tttgcaggtc ttgtttacaa gtggcggaga aacttattgg agttggggtg ttttccatat
    61801 cactgaattt ggtgtgatga acggcctctt tattttctgt cgattcgtgt tgatcatttt
    61861 tatgtcgact ctactcacgc ttactacacc gcctttggaa ttatcggatg cgattgagta
    61921 cttgcttcgt ccattgaaag ccgtacggtt cccagtccac gaaatttcat tgatgctgtc
    61981 gattgctctt cgttttgtgc ctacattgat ggacgaaaca gaaaagatca tgaacgctca
    62041 gcgcgctcgc ggtgttgatt ttggtgaagg aaacctagtt cagaaaatga aagcagtcat
    62101 tcctttgctg attcctttat ttgtcagcag cttcaaccgt gcggaagatc ttgcgactgc
    62161 tatggaagca agaggctaca aaggtgggga aggaagaacg aaatatcgtg tattgcattg
    62221 gcataataga gacacgatgg ttatcattgc ttttgtatta ttaactgtgc tactgatctt
    62281 tttgagagga taaacgttca gtgggccgct atctattctt ttcttgctga tctgtttgca
    62341 agaaaggatg cgagcagtgt atgacaagaa atattagggt ctgtggcaga ctaaggtcac
    62401 aggcctcttt cttttatctg aaaagaaaga acgaaaaaat tttataaaaa aatcattatt
    62461 ccagataacc ttttaggaac aaaggagaga aaaacatggt acgttacaaa gcaatcattg
    62521 catacgacgg aacaaatttt aatggattcc aaaaacagcc aaatgggcgt actgttcaag
    62581 aagaagtaga aaaaacatta caaaaaatgg caaatggaaa agaaatcacg gtctttggtt
    62641 cgggaaggac agatgccgga gtacatgcga ttgggcaagt aatccatttt gattatccag
    62701 aggagcgtcc gttagaacga atgcgtttcg cgctagatac ccagtcacca gaggatattg
    62761 ctgtaagaca agtagaaatt gtttcagaag acttccacgc aagatatttg gtcaaagaaa
    62821 agacgtatca atttcgagtg gatataggga aaccacgcag tccttttcga cgccattatg
    62881 caagttattt tccttaccct cttgatttgg aaaaaattca gcgggcgctt cctgatttat
    62941 tagggactca cgatttcacc tctttttgtg catcaggaag ctcgatagag gataaagtac
    63001 gtacgatcta cgaggctaag atggaggtaa atgaaacaaa agacgaattg ttgtttacat
    63061 ttaggggaaa tggcttcttg tataagatga tacggatctt agtaggaacg cttttgaaaa
    63121 ttggcaatgg ccgattgcct gaagatagta tcccagatat tattgcgaaa aaagatcgta
    63181 atgcagcagg acctacagca catcctgaag gactttattt gtatgaagtg aaatatgaat
    63241 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaatttac gaaaattact
    63301 tctcaaaatt ttgcaaaatt tcggcttatt ttcgaaggag ctacttctgg aacaccgtga
    63361 atcagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacaaccaa acaaaaatag
    63421 ctcgtcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    63481 ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaacggaaaa
    63541 atagttcctc atattttgcc gtttgttgag ctaataccga aggtcagctg attgaacacc
    63601 gtttaagaaa gaggtcgtga gcctgtcatt taactctgag tcacaagtaa caatttcaaa
    63661 aaacagcttc tcatctttga tgaatatcgt gacttgtgga cgaggcgttg ataagtgaat
    63721 catctttttg ttacctattt tttctgtaac caaaaaacga tggaacgttg ttttgattgc
    63781 ccttaatgag gacagtcgga acaggtttgt catttttata tttaaatggc acaaattttt
    63841 ctaattattt gtcatttagc gctgaaaatt tttgctattt atctaaaaaa gtgataacta
    63901 cttaagatga agcagaatat ttacgccata cggcatacaa ccgcgaaaaa tataaaaaaa
    63961 agaaaacgat tgaacgcgtt tttgcagtcg caaaggaaaa gcatggaatg cgctacatca
    64021 agtatcgaga cttggaaaac aatcaggtgt atacgctgat tgtttttgct gcaatgaatc
    64081 tgaaaaagtt gtccacttgg cagttggaac atatgtcttc atatctttta ttatacaaaa
    64141 atagcaaaag caccagtcta cactcttagt aaagaggaaa ctgatccttt tgtctacatt
    64201 cttaaagtac ttaaactaag tactttattt tactctttag gattgataca gtagcatcta
    64261 tccctttatt aataatcttt tattttttta aataaagatg ttgtctccat cttcaggcac
    64321 taaaactttt tcggaaattc ctttttcttt attgaaagac tttaattctt ctcttgacag
    64381 tccccaatgg tttacagctt ccatatgaac ggcaataatt gtggaatctg gtattgcttt
    64441 atgcaattca tataaatcgt ctttccccat aataagagat tctccaacta aaaaatgatt
    64501 atctccagca tttgctacta tgatttctgg attatactga tcaatagttt gtttaacagc
    64561 ttcataccaa actgtatctc ctgtaaagta tagtgtcttc tcagtcgaat gtttgaaaac
    64621 aataccgcaa acattaccta cataattcaa gatttctcct ctgccatgtt tgccttttgt
    64681 tttaaccaat tgtatagatt caaaaactgt gtcttctcgt agtacctcca catttttaaa
    64741 accatatagt cgaatttcat tcgcatcatt ttcatcttgc acaaataatt ttatttcttt
    64801 aggtaggacc tctttcgcta tatcgtccca atgatctaga tgtaaatgtg ttacaataac
    64861 agcatcaata ccgttgataa tatcttcgac tggcattggc aaatcaacta gaggattcat
    64921 ttgatctttt cttggtgatg gaaaaggacc tttcgaaata aatggtggaa gtgttccttt
    64981 ttccgctaac attggatcaa ttaaaaattt tttacctcca tagtctaaga tagctgttgc
    65041 attacgaatg tgatgtatat tcataaacgt tgtctccttt ttgttgatat gaaatatttt
    65101 tagtataatt caattccata caataaataa accgaacaaa aaaagtcttt tactattttt
    65161 acttaattta tgaaaggttg tttaccatgt tagaccaaac agatataaat atcattgagg
    65221 aactatcaaa aaatagtcga atcacaatga aagaacttgg agaaaaagta catttgactg
    65281 gacccgctgt ctcggcgaga gtgacaaaac tagaggaaag tggagttatt gaaaattata
    65341 cagtaaaatt aaatatggaa aagctagggt tttcgattca cgctttttta attataatta
    65401 cgcaaaattt aaatcataaa ccctatttat catttattaa aaatcatgaa aaattcttga
    65461 ttagaaatta taagattagt ggagggggct gttatctttt ggaatgtaga tttacttcaa
    65521 aaaaatcaat gaacagcttt ttggaacagc ttaatgaata tgcgaattat aaattatcta
    65581 ttgttataga ttaataataa aactagcaga tggtaaaaat actaatatgc gagacacaca
    65641 ttcaaccata actatataac ttatcaattt aaaactaaac tgatggaaac aagtaaggca
    65701 aaaacattta tattttgccc tacttatttt tttaattaaa ttcattgatg attcatattt
    65761 agaaaattct atgaaggcca aatgagtatc ctgtcacttt tttagataaa tagcaaaaat
    65821 tttcagcgtt aaatgacaaa taattagaaa tatttgtgcc atttaaatat aaaaatgaca
    65881 ccaagtatat catgaacgca caaaaagacc aacagggtat accctgttgg tctaaa
//
LOCUS       DACCVH010000007        56001 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.007, whole genome shotgun sequence.
ACCESSION   DACCVH010000007 DACCVH010000000
VERSION     DACCVH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.007"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..230
                     /locus_tag="IVV98_000520"
     CDS             <1..230
                     /locus_tag="IVV98_000520"
                     /inference="COORDINATES: protein motif:HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806203.1"
                     /translation="YQLVETQAPIGYELDATPIEFEIERSQTAVVELTKENRLTPGGV
                     VLTKIDDQSGEILQELFLSYRTEKEKRYKPV"
     gene            176..559
                     /locus_tag="IVV98_000521"
                     /pseudo
     CDS             176..559
                     /locus_tag="IVV98_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332801.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(983..1153)
                     /locus_tag="IVV98_000522"
     CDS             complement(983..1153)
                     /locus_tag="IVV98_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7806204.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1347..1526)
                     /locus_tag="IVV98_000523"
     CDS             complement(1347..1526)
                     /locus_tag="IVV98_000523"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806205.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            1913..3025
                     /locus_tag="IVV98_000524"
     CDS             1913..3025
                     /locus_tag="IVV98_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7806206.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3103..3396)
                     /locus_tag="IVV98_000525"
     CDS             complement(3103..3396)
                     /locus_tag="IVV98_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP7806207.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3564..3878
                     /locus_tag="IVV98_000526"
     CDS             3564..3878
                     /locus_tag="IVV98_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP7806208.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3899..5878
                     /locus_tag="IVV98_000527"
     CDS             3899..5878
                     /locus_tag="IVV98_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7806209.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5891..6217
                     /locus_tag="IVV98_000528"
     CDS             5891..6217
                     /locus_tag="IVV98_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP7806210.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6233..6751
                     /locus_tag="IVV98_000529"
     CDS             6233..6751
                     /locus_tag="IVV98_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806211.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6751..8103
                     /gene="celB"
                     /locus_tag="IVV98_000530"
     CDS             6751..8103
                     /gene="celB"
                     /locus_tag="IVV98_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP7806212.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8187..9692)
                     /locus_tag="IVV98_000531"
     CDS             complement(8187..9692)
                     /locus_tag="IVV98_000531"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP7806213.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9784..10374)
                     /locus_tag="IVV98_000532"
     CDS             complement(9784..10374)
                     /locus_tag="IVV98_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7806214.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10553..12199
                     /locus_tag="IVV98_000533"
     CDS             10553..12199
                     /locus_tag="IVV98_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7806215.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12248..12967
                     /locus_tag="IVV98_000534"
     CDS             12248..12967
                     /locus_tag="IVV98_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP7806216.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13446..14393
                     /locus_tag="IVV98_000535"
     CDS             13446..14393
                     /locus_tag="IVV98_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806217.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14405..15325
                     /locus_tag="IVV98_000536"
     CDS             14405..15325
                     /locus_tag="IVV98_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7806218.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15366..16823
                     /locus_tag="IVV98_000537"
     CDS             15366..16823
                     /locus_tag="IVV98_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7806219.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17168..17782
                     /locus_tag="IVV98_000538"
     CDS             17168..17782
                     /locus_tag="IVV98_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7806220.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17775..19499
                     /locus_tag="IVV98_000539"
     CDS             17775..19499
                     /locus_tag="IVV98_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7806221.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19496..20947
                     /locus_tag="IVV98_000540"
     CDS             19496..20947
                     /locus_tag="IVV98_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806222.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21420..23575)
                     /locus_tag="IVV98_000541"
                     /pseudo
     CDS             complement(21420..23575)
                     /locus_tag="IVV98_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
     gene            complement(23577..24623)
                     /locus_tag="IVV98_000542"
     CDS             complement(23577..24623)
                     /locus_tag="IVV98_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7806223.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24773..26062
                     /locus_tag="IVV98_000543"
     CDS             24773..26062
                     /locus_tag="IVV98_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP7806224.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26075..28777
                     /locus_tag="IVV98_000544"
     CDS             26075..28777
                     /locus_tag="IVV98_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP7806225.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28762..29619
                     /locus_tag="IVV98_000545"
     CDS             28762..29619
                     /locus_tag="IVV98_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7806226.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29690..30547)
                     /locus_tag="IVV98_000546"
     CDS             complement(29690..30547)
                     /locus_tag="IVV98_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7806227.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30758..32929
                     /locus_tag="IVV98_000547"
     CDS             30758..32929
                     /locus_tag="IVV98_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP7806228.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32997..33338
                     /locus_tag="IVV98_000548"
     CDS             32997..33338
                     /locus_tag="IVV98_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP7806229.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33614..35368)
                     /locus_tag="IVV98_000549"
     CDS             complement(33614..35368)
                     /locus_tag="IVV98_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806230.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35379..36215)
                     /locus_tag="IVV98_000550"
     CDS             complement(35379..36215)
                     /locus_tag="IVV98_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7806231.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36217..36900)
                     /locus_tag="IVV98_000551"
     CDS             complement(36217..36900)
                     /locus_tag="IVV98_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP7806232.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(37059..38453)
                     /gene="uxaC"
                     /locus_tag="IVV98_000552"
     CDS             complement(37059..38453)
                     /gene="uxaC"
                     /locus_tag="IVV98_000552"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP7806233.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(38492..39991)
                     /locus_tag="IVV98_000553"
     CDS             complement(38492..39991)
                     /locus_tag="IVV98_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP7806234.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(39984..41405)
                     /locus_tag="IVV98_000554"
     CDS             complement(39984..41405)
                     /locus_tag="IVV98_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP7806235.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(41465..42457)
                     /locus_tag="IVV98_000555"
     CDS             complement(41465..42457)
                     /locus_tag="IVV98_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7806236.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            42689..44887
                     /locus_tag="IVV98_000556"
     CDS             42689..44887
                     /locus_tag="IVV98_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806237.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(45345..46217)
                     /locus_tag="IVV98_000557"
     CDS             complement(45345..46217)
                     /locus_tag="IVV98_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7806238.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            46517..47491
                     /locus_tag="IVV98_000558"
     CDS             46517..47491
                     /locus_tag="IVV98_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806239.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            47513..48205
                     /locus_tag="IVV98_000559"
     CDS             47513..48205
                     /locus_tag="IVV98_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7806240.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            48171..49679
                     /locus_tag="IVV98_000560"
     CDS             48171..49679
                     /locus_tag="IVV98_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7806241.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            49753..50856
                     /locus_tag="IVV98_000561"
     CDS             49753..50856
                     /locus_tag="IVV98_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP7806242.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            50859..52196
                     /locus_tag="IVV98_000562"
     CDS             50859..52196
                     /locus_tag="IVV98_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP7806243.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            52183..53061
                     /locus_tag="IVV98_000563"
     CDS             52183..53061
                     /locus_tag="IVV98_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP7806244.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            53058..53981
                     /locus_tag="IVV98_000564"
     CDS             53058..53981
                     /locus_tag="IVV98_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP7806245.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            53978..54388
                     /locus_tag="IVV98_000565"
     CDS             53978..54388
                     /locus_tag="IVV98_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP7806246.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            54392..55960
                     /locus_tag="IVV98_000566"
     CDS             54392..55960
                     /locus_tag="IVV98_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP7806247.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
BASE COUNT        18000 a         9860 c        11424 g        16717 t
ORIGIN      
        1 catatcagct ggtagaaact caagcgccaa tagggtatga attagatgcg acaccaatcg
       61 agtttgagat cgaaagaagt cagacagcgg tggtagaatt aacgaaagaa aaccgactta
      121 caccaggcgg tgtcgtgttg acaaagatcg atgaccaaag cggggaaatc ctgcaggagc
      181 tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtctaa ctacaggaga
      241 agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg tagaaactca
      301 agcgccaata gggtatgaat tggatgcgac accagtaact ttcaagatcg aaaaagaaca
      361 agaagtggcg atctttttaa caaaagagaa tagaaaagtt gctgatagct cagatataag
      421 aggaaacaat ccaacaagca gtggaaataa gcatcttcca aaaactggag aaaccatcat
      481 tagccagttt atattgtcaa tattgggtgt gctacttgtt ttcatcagta taaaatttag
      541 aaagaaacga aatatatgag ctaaaataaa aaattgaata agcatagttt ttaaaatcaa
      601 ctagtaccca tcaattgaat ggaaactacc gattttagaa ggggtataca aacaaatatt
      661 agtatcggag tagagaaggt tgaacccaac cagtaaataa gtaaagacaa ttttgtgctg
      721 cgttgagaag tgaaaaataa acctttgtag taatactagt taataaaaaa tatacaaaaa
      781 cactgcgaaa atcattcttg agtttcgcag tgttttttgc ctaatgactc aagtttattg
      841 ggtaatactt tgattttctt tctacaaata atcagcgatc agttgtaatt ttttctctag
      901 ttttaatggc tctttgtcaa taaggagaaa aacaagtcgg gtcttttgtc tcggaaagct
      961 tcaaccaact cgtgaataaa ggttacgcct ccttgaaagg cgtggaaaaa ccaagtaatc
     1021 gatcaatcac caatttcgca tttggtagaa catgtttggt gagctgaaag taggtggcgt
     1081 tcatgtctgt aactaagaat tctatttctt taggattagt gcagctaagg aaatagtttg
     1141 ttaatcgagg aattttttgt gtaggtaaat tttctcgatt aatttttctg tctcgccatc
     1201 cgcggaaata aaactcagtt tatcctcaac ggaaacgtga gaacgaaatt cacaaccctc
     1261 aacactcaag acagaattct tttggaagac tttggtaaat agcttctcaa ctctttcaat
     1321 gtgcgaataa cggttgtcaa agatacctaa caacttttcg aaataaaaaa taacgacact
     1381 ttttcagtca gtaaagaagt gattttatgt ctgacatgat ttgaaatcga gtgccttgga
     1441 cggataaaat aactttgagc gttccaatgg cttcgacagt ttttacaggt atagcgctgc
     1501 ttttttaggc gtataaccat tggcatatga ttatattatt caaagtggac aatggtttcc
     1561 ttcttcttgt ttttcaccac cattaatttc ctatttccat ctaccacagc agaaccacaa
     1621 tttctacaga cacatggagc agggaagaga actgcagcaa cgatcaatgt ttttttcttc
     1681 tgtaaggttt cgtaagagac ctctgtaatc atcaaatttt tgtctattga tctcagaatt
     1741 tttttgatag aaccattcat aaagcatatc gttctctcag ttgtttattt tgtggtgatt
     1801 taatcataca agaaaacgat atgttttttt ataaaaacat gaataggaaa aatagttgac
     1861 aagaaaatga caacgccata tgatgttcca tagtatttac aacctgtcat agatgactgt
     1921 aaaaaataaa agtaaaaaga aaggacgaca acaggtggat ttttatcagt ctctacaact
     1981 agatccgttt attttaaaac aaaaaatacg agaagcagct tctaaaaaag aaaagtgcat
     2041 gtatatttgt tcattgtttt tacgatcatt attcatcgta ttgtttgcca tttgttttat
     2101 cattataatt acaacattat ttgaatcgaa gcataaacca tacgctgtgg ttttattctg
     2161 tatgttgatg agtattcgtt ttgttgactt tggttataag atttcccatt cgatcatagg
     2221 tttagcaatc gtcatgttct cactattagt agcaccgtat gtccagctga tcaaatggtc
     2281 agttatgggc atgttgattc attttatttt actaagcagc atattaatgg caaccgctag
     2341 tgatcccaaa atggggaatg cttctttgta cggcttttca tatctcttta ttgtttattc
     2401 gttacctaaa gattcgttga acaagaattt ctttacacaa acaagtagct tattattttt
     2461 gtttttttgt tggttttcag ttctccttta cagaaaacat cgagaaaaga acaaagacaa
     2521 aagcttgttt aaagagattt ttttgaaagg catgtattcg caggaaaaaa tttggatgct
     2581 catctatgca tttggcatta gtcttttgat cgttgcagga gagtatgtcc cttttcagcg
     2641 attgatgtgg gcagggtttg cattttcttc tattgtatct agctatggat tgatgtcgat
     2701 tggtttcaaa gaacgagcag tagaccgaat cattggctca ttgattggat gtgttttatt
     2761 tattggtatc agccaattta ttccttttaa ctgggtcggt atattaggtg gtctagcttt
     2821 aggtgtttgt tctacctata gatataaaac agtttttaat tcttttggtg ctttggcaat
     2881 cactgccagt ttattcgggg ttccaggagc agtaacgatc cgcatttttg agaatatcct
     2941 tggggtatgt ttaggaatca tgtatattgg ggtgactgaa atacttatcc gaaaaataag
     3001 agaaaaacac ggtttgaatc attagatgag atcgaataaa aaataaggaa aaagtgaaga
     3061 tacacatgga tgataaattg ctatcattcc atgtgtatct ttttacggta aatcagtgaa
     3121 acgttcgact ttcattttta atttatactt tttacggagt tcgtttattt gagccatcat
     3181 ttcggatttg tgatgctttt cgattgcttc ttcatctttc caacggtcga tcagtaaaag
     3241 agattctgga tcttctagtg gaaagtaata gtcatatttc tcgtttcctt cttctgcacg
     3301 aatcgctttg acaatgtttc tttcgaccat ttcttctgca aattttctgg cttgtccatt
     3361 tgtacttgta tacaaaatat tcactgtgat actcactaaa tcccctcctg aaaaaattct
     3421 atcactagta tatcacggtg ccagaaatta ttattcaaga tatgatacac attttttccg
     3481 caatgctacg gaaatatata ttttgaatag aaaacgctta caagatatgc ttggtttata
     3541 aaaataaaag gagtgattga tttatgaaaa aagcattgat tatttgtgcg gcaggaatgt
     3601 catcctcgat gatggcctca aagacaacgg atttctttaa gcaaaaaaga gaagaggtac
     3661 tcgtagatgc agtttcagct acagaaggcg ataatatgat taagaatagt gattttgatt
     3721 tatttctgat cagcccgcaa acgacgatgt ttttggataa attcaaaaaa ttaggagaat
     3781 ctgttggaaa gcctgttgtt agtatccctt tccaagcgta tgtcccaatc cctacaggca
     3841 tccagaagtt agcagaggtg atcgaagaga acatatgatg gaataggagt ggatgataat
     3901 gaaacagaag gaaaaattgc tgttgagata tttgattgat cacaagaagg agtatgtcac
     3961 cagtcaacgt ttagcttctg aattgttatt atctgatcgg acaatccgta attacttgca
     4021 gcggatcaaa gagttagtag aaaaaaacgg aggtaagatc attgctaaac caggttatgg
     4081 ctaccaactg catattttac aaagactgac atttgacttg tttttgagtc ggcaagaaat
     4141 agtacctgga tatgctagag aaccgcaagg attttatgag tccgaagatc gacaaaagta
     4201 tatattgaac caattgcttt tggaagatgc cattcttttt atggatgatt tggcagaaga
     4261 gctttatatc agtcgttcca gtttgacaaa ggacatgcaa gaaatcaagg agcgattgat
     4321 tccatattca ctaaaaatcg tttctaagca tggtcaaggg acatggatcg aaggggaaga
     4381 aagaaatcga cggcatttta tcatggatac tttttttgga aaccattatg gaaattcatt
     4441 gaaagaatat ttagggcaaa gccgtttttt cccagacatc agttttgaag agctagtcat
     4501 tatcattctc gatgaaacaa gagaagctaa gttaaaagtt tcggatttta tcatacagaa
     4561 tctgacttta cacttggctt tggggatcaa acggctccga gaagggtttg aaatcaagga
     4621 attaggcatc gaacaagaag tttctaagcg agtagagtat caagtggcgc agcggatcgt
     4681 tcaacgtatt gaggtaatcg caggtgtatc gtttcccgaa gaagaaattg cttatttgac
     4741 attacatctc atggctaagt cgaatcacaa agaaaatcaa aatgatcagg aactatcaaa
     4801 ggaattagcg aaagttctga aaagattgtc tcaggaattt catttttcat tagtagagga
     4861 tctccagctt ttcaatggac tactcgatca tttgtcaccg atgatgattc gattgagccg
     4921 aggtattcgc attgagaacc cattgactga ggagataaag aaagaaaatc ccaaagtctt
     4981 tgacgcagta aaaaggcatt tcagcaacat gccggctttg aaaaactata ccatcaatga
     5041 agatgaatgg gcctatttgg ctttgcatct catggcggca ttggaaaaag aaagagctgc
     5101 gcataaacta catgcattga ttatctgtgc aacgggttac ggcagtgccc aactattaaa
     5161 gaatcgcgta gtcagtgaat tcggtaaaaa tattacagtg gtaagtgtaa aaggctatta
     5221 tgagatcaat gaaacaactt taaaaggaat cgacctgatt atttcttcta ttgatctttc
     5281 gacaatgttt ttcaaaattc cagttttaca tgtcagtatt tttttgaatg aagatgatgt
     5341 tcgtaaaata cgaaaggtag ttggagaatc tataccctat cattcctcag atagaccgat
     5401 accagcattt tctctacagc aaaaaaagca gatttacacc gaacagttgt ctgaaaaatt
     5461 tttcaagact tatacgtacg aaccgaaaaa ggaagaaatt cttcatgatt tgctgcaaaa
     5521 gctgagcata aatgaagaag aaggatatat aagagaaatg cgaaagcaga tccagcaacg
     5581 tgaaaatatg ggacaaatca tattcagtga tacagtggca gtcccacatc ccgctgttcc
     5641 agttggaatc gaaacaaagg tagccgttgc attgattcct tctgggatgc agtgggatca
     5701 atatcaagaa attcattttg tttttttagt ttcgccttct tatgtcgaaa atgaaggaat
     5761 tacggtcgtg actaaagcaa tcgttaggtt agttgaccag ctaaaagtac agcaggaaat
     5821 cttagctgaa cctatttttg agaatttcag cagtaaattt atcaaactga tcgaataagg
     5881 aggaaaacag atggctgaaa aaataaacag tgaaacacta caagtgactt cttttgatat
     5941 cattttccat agcggaaatg cacggacact gatacatgaa gcatttcgct cgatgcgtaa
     6001 agagatgttt gaagaagtag aagagaagtt gcgacaagca aatgaagaga ttcttcatgc
     6061 gcatcagtca caaactcaac ttctgaaaga atatgccagc gggacaaaaa tagaaatgga
     6121 aattatcatg gtccatgcac aagatcatct gatgacgacg atgacattat tggaagttgc
     6181 acaggaaatg aattatttgt atcaaaaaaa taaatagaaa ggaaggatca ttgtgcagga
     6241 tacagtaaaa aggaaaatcg aattagaaaa aaagcaactt agtttgaaaa acatgtattt
     6301 caatcgttat ctaatcgtac gttacctgac tgcctttttc tttttcatga acatgcaatg
     6361 gatgattctg cttctatcag ctaaaagttt aggaagtagt ttaccgatga ttctgatttt
     6421 agctattttg cctgcagtag gagaacaagt aaagctttat cgaaaacacc aaacgaacgt
     6481 tccatggaca aagtggtatt ttttgttcca gagtgtcttt aatttattag tgattccagt
     6541 gttgtttacc tcaggattta cattcttgta tccttttatg gcaaataaca atggaggaca
     6601 gttatttgtt ttcattcttg ttgtaagcgg tatttttgcc agtgcattta tacagtatcg
     6661 tttaaagaaa atttcactca accaagacca acagtatatc cgtattaaac aatatgaaaa
     6721 agcgttatat ttaggaaagg agaataacta atgtttgatt ttttgcagaa atacctgatg
     6781 ggacctatgg ggaaaattgc gcaacttaaa atcgttcggg ctgtcatggc agcggggatg
     6841 gcttctattc ctttcacgat tgtaggctcg atgtttttgg ttttaaatat tttgccatta
     6901 ccgttcccat ttttagaagg attttttaat gcaacttttt tcaaagttag tgacttgtac
     6961 atgatcgtca atacaatgac gatggggatt ttatctattt actttgccat tgtgtttgct
     7021 tatgaattaa cgtcaattga acgagatgaa caaaaattaa atgttaatcc gctcacgggg
     7081 gcattactat ctgtttttgc attctttatg tgtatccctg aattgatcat gactgatggt
     7141 aaaatcagct tgattgcttc tatcaatgag acagaaactg tagtaaatgg tattaggatg
     7201 ggctcttttg tcgaacgttt aggaacttca ggaatcttta cagctattat tatgtcgatt
     7261 attgcggtcg aattgtattg tatgtgtgtc aagagaaatt gggtcataaa aatgccagat
     7321 gttgttccgc caggagtttc tcgttctttc actgctctga tcccaacatt tgtcattgcg
     7381 tttgtggtga tgatcatcaa tggattatta gttgcactag gaacggatat cttcaaaatg
     7441 attgctatcc catttgggtt tgttacgcag ttgacgaata catggcttgg tgtcatggtg
     7501 atttatttct tgatccatgc attgtggatc gtagggatcc atggagcgaa tatcatcact
     7561 tctttcttga ccccgatcgt attagctaat atggcagcta acgcacaagg cgcaaattat
     7621 ccgttggcag gagaattcaa caattcttat gtaaccgttg gtggatcagg tgcgacttta
     7681 ggattgatca tctttattgc attcctcgcg aaatctgatc agctgaaagt gttaggaaaa
     7741 gcctcacttg taccaggatt attcaatatc aatgaaccaa tcattttcgg gatgccaatc
     7801 gtctacaatc cctatttagc ggttccgttt ttcttagctc cgatggcttc tgctacactc
     7861 gcttattttg ccattcggct ggaaatcgtc aaaccgatgc ttgcacagat gccgtggcct
     7921 tcaccagtcg ggatcggagc atttgttggt agtggtggtg attggaaagc tgctgtgtta
     7981 gcagtcattt gtgcaatcat cgcattcatt atctggttcc catttatcaa attctatgat
     8041 aataaattat taaatgaaga aagagaaaag gcagcagaat tagctagtga aaagttaaaa
     8101 tgatttctaa gaaaaaagga actgtgacaa aaaatcacag tccctttttt tcttagaaat
     8161 gggaaaccac tagtatataa ataccattat tcttcaatca accgcttcac gattgcataa
     8221 tccccttcat aaggttcatc tacaccattg attttttgat agggatccac gccttttccc
     8281 gcaataacga ctgaatcttg cggagcgctt tctgctaaag cgcgtcgaat cgcttcagga
     8341 cgatccattt cataatgaac gatcaaatct ggattagtaa ttgcttcatt gatttcttcc
     8401 gcgatttttt tcggatcttc aaatgctggg tcatctgccg tcaaaaaggc gatgtcagct
     8461 gtttctgata gcacttttcc aaaatcatgt cgacgggaga ttgctttgtt tcctgggctg
     8521 cctaatacaa caattacacg gccatctgga tgttcatttt tggcaaattc cagcaatgtt
     8581 ttcaagctta gataattatg tgcatagtcc acatagacat gcgctccatt ggattggatc
     8641 aattgatcca ttcggcctgg tacacgagct tcttttaatc cgtcttgtgc atcttgactg
     8701 gaggcacctg ttagtgctgc ggcaatgatc gcactggctg cattttcttg gttgaatcct
     8761 ccagccagca aaatatcata agcagtatcg cagatagcta agcgatcttc atgagaagat
     8821 aaagtaaaac cgtgagtacc tttatctgaa cggatcactt gataattgct ttcttccgaa
     8881 cgaccataag tgatcgttgg aatctggaat agatcggctg tttccctaag taaatcaaaa
     8941 tagtcacttt catgatttaa aacaactgtt tttgaattca agatcaattg tcgcttgcaa
     9001 tagaaatagt catcaaatgt cggatgttcg atcggactga tatggtcagg cgagatattc
     9061 aagaagattc cgacatctaa agtcaagccg tatacgcgtt gtgttttgta agcttgtgaa
     9121 gaaacttcca tcactagatg agtcatacca ttttcaactg cttctgacat catacgatat
     9181 aaatctaatg actcaggcgt tgtcaaatgg gatttgaaat atgttttgcc atctaacgtt
     9241 gtattcatag tagaaagcaa tgctgttttt ttatttgttg tgtgatccaa gattgctttt
     9301 gtaaagtacg cagcagttgt tttacctttt gttccagtga atccgatcac tttcaattta
     9361 ttttgcggat agtcgtaaaa agccatagca agaagcgcca ttgctttacg gatatccgtt
     9421 acgatgattc ctactgctga attttcgtat ggttgttctg atacataata ttgaataccc
     9481 tgttcgattg ctgaatccaa atattcttct ttgaaattca ttcctttaca gaaaaacaaa
     9541 gtagaagcat cagcttttct tgaatcataa cttaactgaa gaaattcagc tttttctggt
     9601 acatcaagat gccagcctct tgttgaaaca aattctttta atagattttc ttttaatagt
     9661 aaatgacgga tgtcttctaa agagaagctc attgattgat ccctcgcttt attcaatttc
     9721 ttggtttatt atagcacact ctttttaata tatcgtttgt ttccgctatg acaaaatcca
     9781 gctttattca aattttcttg acacagggga caagcggatg agtattttca taaacaatga
     9841 actgactgta atagatagga gaacgaatag tgtctccaac aatccaaaaa cataataatt
     9901 caaaaagacg ataagactat tggtaagtaa aagtccttgc ggcattggaa gccgaaaaaa
     9961 tttgtggaaa ataatcggcg gtatcgttat accgccattt gaggccccga ctgtgtacaa
    10021 tgtgtaaacc ccaagactga acaaaagact tcctgaaatc agtgaaaaga aatgtgagga
    10081 gatcatttcc acttttggaa caatctctaa aacaacagga aaaagcagac ttcccgctac
    10141 agtcttaaaa aatactgatt ttcctaatag gacagcggct agaagcagca tcataagatt
    10201 gatgctccaa acagtaactg agcgttggat agaaaaggcc gtttcaacta aatgtccgat
    10261 ggcgcccact ccggcggaag ctatatcgtg agggagcaag aaccaattca atccaactgt
    10321 gataaagaaa agacctaaaa atataacggg tagttttttt atttcttgtg tcattgatat
    10381 ctcctataaa tgttagccat aaaaggctgt atatttcttt actttaccaa aaaaacgaaa
    10441 ccgaattcaa aaaaacaatt gttcttataa aagttatata aaatcgattg ccagtttctg
    10501 ttttaccaat taaaatgata gtaatgtttt gtagaaagtt ggaatctgac cgatggataa
    10561 tcaaagaaaa ccagcattag atcaattaac accgcaagaa aaaatggcac gaggctctgc
    10621 ttggatgacc gccagtaata tcatttcaag attgctaggc gctgtctata tcattccctg
    10681 gtatgcttgg atgggcgaaa atgctaaggc tgccaatgga ttattcaata tgggatacaa
    10741 tatatatgca ttgtttctac tgatctctac agcaggaata cctgctgcga ttgcaaaaca
    10801 aactgcacgc tataattcat tgaatgaata tggcacttca cgacgattat ttatccgtgc
    10861 attacagatg atgggcgggc taggcctgtt gtttgctttg ttcatgtaca tcgcctctcc
    10921 ttggctagct catgcttctg gtggcggaga agaactgatt ccaacgatgc gttctttgag
    10981 tatcgctgta ttggtttttc cttgtatgag tgtgatacga gggtattttc aaggcaatca
    11041 agaaatgatg ccttatgcgc tgtcgcagat tgtagaacag gtggcacgta ttttttatat
    11101 gctattggct acattcatca tcatgaaagt catggatggt gactatgtga cggcggtcac
    11161 gcaatcaact ttcgcggcat ttatcggtat gctagcaagt attcttgtcc ttttgtattt
    11221 tttgaagaaa catcaagcgt atacatcggc gtttattcac tacagcgaaa acaaaataaa
    11281 tattgcaacg aaggaattgt tgttagatac cgttaaagaa gcgattccgt ttattattgt
    11341 gggttcaggg gtaacgatct tcaaattagt cgatcagttc acttttatga agatcatgtc
    11401 tgcatccacc gagtattcca atgcacagtt actggatctt ttttcgattt ttagtgccaa
    11461 tccagataag ttgacgatgg tagttattgc attggcaaca tcgatcgcgt ctactgggtt
    11521 accgttgatt acagaagctg ttacgttgaa agatcgagta ggtctggcaa aattgacaag
    11581 cggaaattta cagttgtttt cattttttat gtttccggcg acatttggtg ttatgttact
    11641 tgcctatccg ctaaatacat tattttatac accggattct ctaggaagta atgtactgat
    11701 ccaagcaagt tttgtaggac tcttcctagg actatatatg ctagtttcca acatgctgca
    11761 aggaatgttt gaaaacaagg cggcaattaa ttatttggtt attgggtttc tagtgaaact
    11821 ccttcttcaa tacccagcca ttcgtttatt tgaagtatac ggccctttat tggcgacaat
    11881 gatcggattt gctgtgtctt gtaccttgat cttaaagaga atccatgaag tagcccgctt
    11941 taaaccaagt tttgtctggc gcaggacatt gctgatcttt attcttacct tgattatgct
    12001 tttggcttcg tggatcacaa agatgatttt tggtgctttt ttaaacgaag atagcaaatt
    12061 ccagtctcta ttgttgattc ttgtagtagc aggtataggg gctttagtgt atggttattt
    12121 agctttgaaa atccgcttgg cagaaagact actaggacca ggaatagcgc gtttacgaca
    12181 taaattaaaa ataaaataag tgaatcagaa gagctagatt gatgctcttt tgaaatgggg
    12241 gaaacgcatg cgtttagata agtttttagc agatatggga cttggcagcc gcaaagaagt
    12301 caaaggattg atcaaaaaag gaacgatcga agtcaatgga caagtggtga aaagcgataa
    12361 agcgcaagta aatgaattcg aagatgcggt tacttattta ggagaaatca ttacgtatca
    12421 aaaagatttt tactacattt tgcataaacc tgcaggagtc atttctgcta ctcaggataa
    12481 tcatgatcaa accgtaatcg atttattgga agaccaggat tatcgggaag atctttttcc
    12541 agtcggccga ttagataaag acacagaggg cctcttgatt ttaacgaatg acggggtgtt
    12601 tgcccatcag ttactatcac ctaaaaaaca tgtggagaaa gaatatctag ctgaggttag
    12661 cggtataatg acagaagaag atatccgttt atttgcagaa ggactgatta ttgatggcga
    12721 tgagcagaca ttgccggcaa aactccaaat tgatcaagta gatcaagaga cagaaacttc
    12781 aattatccgt ctgattttgc atgaaggaaa gtttcaccaa gttaagcgaa tggtcaaagc
    12841 agtaggaaaa gaagtcttat atttaaaaag aatccgtatg ggaaaatttt ggctgcctaa
    12901 agatttgaat aaagggcaat atcgacccat gaccaaagaa gagctagaac aagtgagaga
    12961 aaaataattg aatggatagc taaaagaata agcagagtag ttgtagcgcc atctgaaaag
    13021 cagacttgtc cgtctgactt tcggatggct tttttgtgaa atttcggctt atttccgtag
    13081 aagctacttc tggaacaccg tttgttcgga ataagggact gtgacaagac ttttgttaca
    13141 gtccccattg ttccttgtga ctcagagtta gatagtaagg acacgatctc cctaatactc
    13201 aggccaaaac gctgaattca caacctctga taaacggtgt tcaatcagct gaccctcggt
    13261 attagctcaa aaaacggcaa aatatgagga actattttcc cgtttttttc tctaatactc
    13321 aggccaaaac gctgatttca caacctctcc tatactttgt ttcattttcc ctatactttg
    13381 tttatttatt ctcattattg aaagcgctat aattacgttg cgaatgaatc gaaaggggtt
    13441 tttagatgaa aaaacgaaag gggttcaatc atttttttat gaatctatgg cgttataaag
    13501 cacttgtcct gatggctgta ccgggtatgc tttggatgat ttttttcttt tacatacctg
    13561 taatggcgaa tgtcgtagca ttcaaaaatt ttcatatttc agcagatggg ttcttggcta
    13621 gcttgaggga aagtccttgg gtgggttggg aaaatttcaa atttttattt tcttcggatc
    13681 aagcatttct catcactaaa aatacaattt tatataatgt agcatttatc cttttgaatc
    13741 tgctgatctc agtcgtattt gcaatcatta tgagcgagtt gagaaataaa cgactcgtta
    13801 aagtttatca aacgatgtcc ttactacctt attttctatc ttgggtcatt atcagttact
    13861 ttgtttacgc ttttttaagt cctgacaaag gaatattcaa tcagtggatc actggacatg
    13921 gaggagaagc tgtcaattgg tataatgaac cgaaatattg gccgtttatc ttggtgttca
    13981 ttggtacatg gaaagggatt ggttataaca gcattattta ctttgcatct gttatgggaa
    14041 tcgatccgac ttattatgaa gctgctatgg ttgatggagc tagcaaatgg cagcagatca
    14101 aacatgtgac gataccacaa cttattccac taatgacgat tttaacgatt ttagccgtag
    14161 gaaacatttt ccgagctgat tttggcctgt tttataacat tcctaggaat tccggtgcat
    14221 tatatgatgt gactcaagtt ttggatacgt atatctacaa tggcctgaca tccacaggag
    14281 attttggtat gacggctgct gcaggacttt accaatcagt tgtcggcttt gtcttgttga
    14341 tgatcacaaa tacgatcgcc cgacgttttg atagcgattc tgcattattc taaggaggaa
    14401 aaaaatgaaa aaaaagaaag tggagagagt ccaagtccgc tctttcaata agacggctaa
    14461 ttttttctct aatataatga ttgcactctt tgctatttcc tgtattttgc catttatatt
    14521 tgttatcgcc atctctttta ccgatgagtc catattgtcg actcacgggt acagtttttg
    14581 gccagaaaag ttcagtatat ttggttatac gtacttgttc gaccagatgc aggataaaat
    14641 tttccaagcg cttttcgtca ctgtacttgt tactgtttta ggtacactga tcaatagcac
    14701 ggctacttct ttatatgctt atgcgatttc acggtcaaac tttccattcc gtcgtttttt
    14761 taccgttttt tgtttgatta cgatgttgtt ctcaccaggg atggtggcca attatcttgt
    14821 tatgacaaat cttcttcagt taaaagatac gatttgggca ttgatcttgc caatggctgt
    14881 cagtcccttc aatattattg tgatgcgcac attctttaaa cgttcggtct ctgattcgat
    14941 tattgaatcg gcacggatcg atggagctag cgaactgcga atatttgttc agatcgtttt
    15001 accgttagct gttccaggta ttgcgacaat cagtttattt gccgcattgg gttactggaa
    15061 tgactggttc aatgctttac tatacatcca agatgataag ctagttccac tacagtatct
    15121 tttgatgaaa atccaaagta atattcaata tctgacacaa aattcaggag caggaagcca
    15181 attgacaggc ggattagcct cagttccagg agaatctgcc agaatggcga tcgtagtcat
    15241 ctcgacgttg cctattgcga tcagctatcc atttttccag aagcattttg tcaaaggtct
    15301 aacaatcggc ggagtaaaag aataaagaaa caaaaatata aatcataaaa ttaggaggaa
    15361 gaaaaatgaa gttatggaag aaactagcct ttacaggtgt ttcagcgttg ttgttgggaa
    15421 cattagcagc atgcggaggt tctggttcta aagaccaggc agaagctagc aattcggaca
    15481 ctttgcagat gtatcaaatc ggagataaac cagataattt cgatcaattg atggaagtag
    15541 caaacaaacg aatcgaaaaa gagatcggtg taaaagtcaa tatcaattac attggctggg
    15601 gcgattacga aaagaaaatg aacgtcatca tttcttccgg ggaaaattat gatatcgcct
    15661 ttgcgaacaa ctatgtttcc aatgcccaaa aaggagcctt tgctgatttg actgaattag
    15721 cgcctaagta cgctgaaaaa gcttataatg atttagatga agcatatatt aaaggaaatc
    15781 tggtcaatgg aaaattatat gctttcccag tcaatggaaa tgtctttgct caacaagtac
    15841 ttacttttaa caaagcttta ctagataaat acgatctttc aattgatgga atccaatctt
    15901 acgctgatgc agaaaaagtc ttgaaggaat tccatgaaaa agaaccaaac acggcagctt
    15961 ttgccattgg acaaggcttc aaagtccaag ggaactttga ttatccttta gggaatacgt
    16021 taccatttgc tattgatctg gatggagatg attcgaaaat catcaaccaa tacgataatg
    16081 aaacgtatat cggactgtta cgtacaatgc atagctggta caaacaagga ctcattccaa
    16141 gtgacgctgc aacgagcaat aaggattatc cactagaagg aaatacttgg ctaatgcgtg
    16201 gagaaacaca aggaccgtat gattatggcg atacaatttt gacaaatgca gcaaaacaag
    16261 aacttgtctc aaaagcaatt actgttccac taaaatctac agctcaagca caaatggcaa
    16321 attttgtcgt atcaaatact tcaaaaaata aagaaaaatc agtagaactt ctagggctgc
    16381 ttaacagtga tccagaatta ttgaatgggc ttgtttgggg gatcgaggga gaagcatggg
    16441 aaaaagtcga tggttcagat gataaaatca aattgctaga tggttatcag ccaaatacac
    16501 atatgtctgc ttggaataca ggaaacaaca agattctata tacacaagag tctattacgg
    16561 atgacatgat tgccaaacgt gatcaatcga ttgctgatgc agaaacttca ccgattttag
    16621 gattcagctt caacactgac agtgtcaaaa cagaattaag taatatttct aatgtcatga
    16681 atcaatattt agatggattg aatacaggga ctgttgatcc agatgaaaca ttaccgaaat
    16741 tgaaagacgc tttggacaag gctggctatg ataaggtatt gaaagaaatg caaaaacaat
    16801 atgatgagtt ccgacaagaa taataatgaa taaagacaaa ggggttgtga caaaagacgt
    16861 gtcacaacct cttgttccga ataaacggtg ttcaaaagcc agtttctcgg tattaagcta
    16921 aatatatgta aaaatgtgga aagccatatt cacaaaattt ttcttactac tcgaaactaa
    16981 gcggctattt cacaaactct tggtaaacgg tgttcaatca gctaaccctc ggtattcgct
    17041 cacaaaacga caaaatatga ggaactattt ttccgtttgt ttctctaata atcaggtcaa
    17101 ggtgctgatt gcccaacctt tttttgtata atgagaaagt ataaacttaa tgtttggagg
    17161 agaagatatg ttagggaagg ttttggaaga gttatttatc cggatctggg tcattataaa
    17221 actaaccttg tatttctgga tatatacatt tgccggcggg atcatctttg gattaggtgc
    17281 ggcatggaaa acagtcaatg aactatttta tttgtacgga ttcgagtata aagaaatcac
    17341 aataaaaaga ggctggaata tatataaaag aaatttttta agaggcaatc tgctatttag
    17401 tttattttta tctggtactg ctttattgag ttacaattta tatttatctg ttcaaatcaa
    17461 agggctcatt tttttagcta ttgattttat tttacttttt gccttgctct gcctatttgc
    17521 tacttatcaa tacagtatga ttttagatag tgaatatacg atctctgttc ctaatctgct
    17581 aaagctaagt tttatttcgg ttttttccag cttttcgtct tttctaaaaa taattattgg
    17641 tagcggtata attttaggcg tgacttggca attcaaagga ttgatcctgt ttggtgtcat
    17701 tggtcttttg acggtttgga atggtacgat gacaacacat tggcgtgaag aattagataa
    17761 acagttggaa agttatgaat aagtttcgga ttctattttc aaaaggaacc ttactaaatc
    17821 gtctgttgcg gaaatacgcg gttatcatga tcggtgtaac gatgactgct accgttattt
    17881 ttagtatcca tacttgggaa caaaatcaaa aacaggcaga aaacatgaca agtgatgccg
    17941 ttcaaagcac aagcagaatg ctgaatgata aaacaacctt gagtaggatc atcaaaaacc
    18001 agcttgtagg gaattccgaa aagatcgaaa atgtgacgac ctacttaaca aaacccatag
    18061 atcagtatct gatgtatgta tacgaacagc aaaacagtac cgatgaatta gtttctttcc
    18121 caaatcaaat caaagatctc tacgcaaatt atgaagaact aagtgcgata tatatcgtgt
    18181 tgaatcaact accggagtat tatgaatctt ctagagaaaa caaaggtggg gaaataaaaa
    18241 aggggacacc aaaattacta gacgcctttt atatcaagtt gcctatcaca caaggaggag
    18301 ctgagtcagg aagtattttt attggttttc aaaagaaaga actagatatg attttagaaa
    18361 atctaacgtc attcaatgga ctctctttat acatgatttc tggaacgaca aatcgactat
    18421 acacattcca tgataataaa atagctaaag aaacgtttga aagacaagaa atgatcatca
    18481 cagagagtct gaagaaaaat tcacaattgc cgattgacga tctggaaaaa aacaattttg
    18541 ttcaacacca agaactgtct gatgattatc gtatattagc tgtactagat aaaaaaagtg
    18601 taaaaatcga aacgggaaaa aatcttgccc cgctgatcat tggtatcatt attttagaca
    18661 atatactgct tatctttctt tataaaacat tcaaacgata ttcacagcaa gtatctatcg
    18721 tcatgcaggc catggatcaa acagcagcag ggaatttaga gacgcggatc gacataacaa
    18781 acacggaata tgaactgaag gaactttcaa tcggtatcaa cgaaatgttg gatagcatca
    18841 atcagtttgt agaagacatc tacaaattag aaatcaaaca gcaagacgca catatgcggg
    18901 cgcttcaagc acagatcaat ccacactttt tatataatac attagaatat atccgaatgt
    18961 atgcaatcag cgaaggaagt gaagaattag cagatgttgt gtatgcgttt tccgctttgc
    19021 ttcgaaacaa tacgaatcaa gagaaaacga tcactttaaa agaagaactg gacttttgcg
    19081 aaaaatatgt ctatttgtat caaatgcgtt atcctaatcg agtagcctat cattttatga
    19141 tcgatcctga tttggaaaag atcgaagtac ctaaatttgt gatccagcca ttagttgaaa
    19201 attattttaa acacggtatt gattttactc gattcgataa tgcgctaagt gtcaaagtct
    19261 tgcaggaagg caaacgggta aggatcatca tcaaagataa tggaaaaggg atgactgaaa
    19321 aacggctaaa acagattgaa gaaaaactgt ctcatcctaa agtggaactt cacggttcta
    19381 tcggtctgca aaacgtgaat gaacgtttac gtgccagctt cggcagcagt tattatatgt
    19441 cgcttgagaa taatgagaca ggtggactga ccgtttctat tacattcaag gagggatgag
    19501 cgtgtatcaa gtgttattgg tagatgatga atacatgatt ttgaatgggt taaaaaagat
    19561 aattgattgg caaagtttag gctttcaaat agtagcaaca gcagagaatg ccaaagaagg
    19621 actagctgta cttgaacagc gacagattga tttagtagta acggatgtga caatgccaga
    19681 aataaatgga ctggaattta ttgaagcggc tcaaaaagaa cgtcataatt ttgaatttat
    19741 gattttatca ggataccaag aattcgatta tttgaaagga ggtatgcaat taggcgccgt
    19801 gaattatttg atgaaacccg tgaataagtt cgaattggtt gaaagcctca agaaaatcaa
    19861 aacacggtta gatcagcaaa atgaacaaaa aaatcaacaa gaaatctatc aagaactgtt
    19921 attcagtcaa tggttgaatg aagaattgga tgaaataagt gaagaagaaa taataggaca
    19981 aataagtgag aagcagcata ggatagtatt gattcaactg gcaagaactc atgatactct
    20041 tatcaataga tggttgcaag aacggcaaca aatcttttac tatcaacgaa attacggaga
    20101 ccgtgtattg atcacgttgt tgttggaggc agatgaagtt gatggcttct gttgttttgt
    20161 tcaagaaaac tttcctgatc aggaatggct gatcagtatc ggggaagaga cagattcttt
    20221 ggacaaaatc cctgaaacat tccaacaagc gaaagacaat ctacagttgc atcaatttta
    20281 tggagataaa gacgagcatg ttttttacgc agtacaagca gaaacaaaag atcaaaccat
    20341 cgatttttca agtttcagac gcgtgctgca aaataaacaa ttggaagtcg ctcaaaaaat
    20401 gatcactgat ttttttgaac agtttcagtt agcagccatg atgccggaag atatacgata
    20461 ttccagtttt ttactgttta tggagattca acgggaattg attgatctgg aagatgagga
    20521 atatttacaa ggaatcgaaa aaatccatca ggcaaaaacg gtgcaagaac ttcagcagct
    20581 acttctgtca ttcatcaaaa agcatcagag acagaaaaag tacagtgaca atgtggaaaa
    20641 agtaatcgta atcctgcacc agcattatca agaaccactt acactcaaag aagtgtcaga
    20701 aaacctgcat ttaaatgtca tgtatctagg acagctgttc aaaaaagaaa cgaaaaaaag
    20761 tttttcagct tatttgaacc atttacgtat ggaaaaagcg aaacaactgc ttttgcacag
    20821 taatcaaaac atcaatgaga tagcaagtga gattggctac aacaacacca cgtatttctc
    20881 taaattattc aagaaaatcg tcggcagatc ccctaaagag taccgagaaa acagtggaga
    20941 atcataaaaa aaaaagccaa tgtaatgaaa taacttataa aaaattgtct agaaatctaa
    21001 ttttgggctg ttcttattac ttgaggcaag gcagcttttt catgacctct cgataaacgg
    21061 agttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgtg gaaagccatt
    21121 ttcacaaaat ttttcttaat actcgaaact aaacagcttt ttcacgacct ctccactaaa
    21181 tggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa tggcaaaata tgaggaacta
    21241 ttttgccatt tgtctctcta atactcaggt cagaacgctg atttcacaac ctctcaataa
    21301 acggtgttca aaagcttgca tctgcggtaa taagaccaac caaacgaaaa atatgaggat
    21361 ctatttttgc ttggctgttc ttattacttg atgcaggaca gctttttcac aacctcttgt
    21421 taattatagt ttgataagga aaaaggcaaa tcttttgctt gatatttctt agggtgaggg
    21481 atgatcccta attggtaaga gatcgtgccg cctttcagca aatcttgatg ggtaaaatat
    21541 aatttcgtat attctctgtc catccgtttg attttatgga taaattgttg ctgcggccga
    21601 ttaggcgttg cttcaatcgt caattccttt ccatttgaca aaagcaaaac agccttgtca
    21661 attaatggca taccgataac atattcaccg gttccaggcg tgacaggata aaatcccaga
    21721 ctattgaaga tataccaagc ggccatactt ccattgtcct catctccagg gtaacccatt
    21781 ggagaatcgt cgaaggtctg agtcatcaac tgtttaagca gtggctgtgc catttcaggt
    21841 tgtcctatat aactgaacaa gtaaggatag tgaaaacttg gctggtttga aatagctaat
    21901 tgtccaaatt ctatcgcggc catctcactc atttcgtgga tctcaaaacc atatcctcct
    21961 gggtcaaacg ttgggggctg attgcacagc tcaatgagtt tttctttata tctctcactg
    22021 ccaccatatt ttccgatcag tcctgaaaaa tcgtgataaa cagcaaagct gctttgccaa
    22081 gcacttcctt ctgcataatc ttgtccccaa cgattagctg aaaatggttc tctgaacttg
    22141 ccatctttat cttttgaacg cataaatcct gactcatagt caaagatatt ttgatagttc
    22201 aatgattgct gctgatattt cttcgtcatt tcctcttctt ctagtacctt ggcaacttgg
    22261 ctaatacaaa aatcgctata agcatagtct ataatgtgtg attgactgat tcgtggtagt
    22321 gattaggaac atagccatat gtcaagtaat cttctgttcc ttggcgtcca taatttggat
    22381 gtttgctttg aaccgtagca cctttttcca ttgccgttag aaattcaggc atcaagtctc
    22441 gtcggatatc ttttacagca gcatctgcaa tgaccgcatc gatcaatgtc ccaggcataa
    22501 gtccacgttc atcaggagac agccattttg gcaaatagcc actttctcta tagctgttca
    22561 aaaaaccttc cagcatttct tcgtattttt ctacagcaat caaagaataa agaggataaa
    22621 ccgttttata cgtatcccaa aacccattat ttgtatagag aacaccaggt tttatagatc
    22681 gactagtcgt atcatagtgg attttttgcc cactaggatc aatttcataa aatgtttgtg
    22741 gaaataaaaa cacccgatat aaattatgat aaaacgtccg caattgttgt tgatcatggt
    22801 gtgtgagctg tatacgatca aaataggact gccattgttc ttgactgtga gcaaggtaag
    22861 tctctttgct ttggttttgt tctagttcca ggttataagc tgcttgttcc gagctgataa
    22921 aagatgtccc aaatcggata gtttgttttt ttgtctgttc aaaatacaac gggatcgagt
    22981 cgctattttt gttggaaaca gctaactcat caattgttaa aggatattca aatctcaata
    23041 taaaataaaa agaaaaatca ggatcttctg aaccagcaaa atgtgtgatt tttccttcca
    23101 ctgtgtaagg atctataaca aagagctgat ggcgtcccgg aaaggataaa agtaaaccgc
    23161 tgtcattttt gctgtaatca atagataaga ttccgccata catgctaggt atcaatgtag
    23221 aacagatgcc ataacgtaat tgacagatcg acagatgagt cgggcaaaat atactttctt
    23281 ctgggcggta agaactttga gcatggaaaa gggtgttctc ctgtagtttt ccattgatcg
    23341 gcgtaaacag catatgactg aaatcaccca tccaaggact tggttgatgg gtaagacggt
    23401 agccttgaaa aacgcggtca tcaggatgaa accaccagct gccgttttga tccgtagttt
    23461 gcggtgcaaa ataattcatc ccaaaaggaa cgccagtata aggctggcag ttcccattag
    23521 agaaatttgg ctgattcgct gttgcatgtc tagtatctat ttgaccgata ttcattttat
    23581 ttctcctttg ttgattgtct tttgatgaat gaaactggaa atttactatc ggatggtcga
    23641 tcttttgtct ctaaccaagt gaccaaagca tctcccgcaa gcttacctaa ctgttcaaaa
    23701 tcttgtgcga tggttgtcag tggcgggtca acaagagctg ctgcttggat atcatcaaat
    23761 ccgataattg aaaaatcttc agggatatga taaccatgct gtctcaagag attcatggtc
    23821 tggatagcga caacatcgtt ttcacaaaca aaagcagtta cttcatactt agtgatataa
    23881 gaaagcaatt catctaatgt cgcgcttttg tcatccagtg aagtgtggaa agtcaaacca
    23941 gctttgtcca atgcttcaag gtaaccaagg taacgctgtc gaacggattg tggatgagtc
    24001 tgcgtaccaa acaaataagc gatttttgaa tgtccctgtt cgatcaaata agaggcagca
    24061 agcgcaccgc cttggaaatt atcggaaaga acggtaggaa aaggtaactc atagattttt
    24121 ttatctaata tgacgacagg gaattctttc aatgaaagct caaaaagtaa gtcaagatgt
    24181 tgttctgtat caagagcata ataaatcaat ccgtcaaatt cattgattag ctcttttgct
    24241 gttttatttt gtagaaagtc aagcgtcgtc atcatgacat caatctgttt atcttgcatc
    24301 acagggttca atcccttgct aaaatcacca acagacaaat cagcgacata tggaagaaga
    24361 aacagaatcc gtcgtgtttt tgtaggagaa gcaagaatct gttccggaga agcggattta
    24421 acgaaactgc ctttcccgcg aacgcgataa ataagtccta attgctctaa ttcagtcaat
    24481 gcacgtttgg aagtgattct gcttacttta taggtacgtg aaagttcttt ttcagttggt
    24541 agttggctgt ctacaggtaa ttcaccagtt aaaatagccg tttgcaaatc attaaatatt
    24601 gtctggtaca atggttgagt catataaaca cctcttaatg atatatcata ttcaaataat
    24661 accataatgg atgaaaaagt aaataaaaag atattttttg aaagcgtaga cataattggc
    24721 tgtatgaagt ataatcttta aagatatatc aaatagaaag aaggttttat tagtggttta
    24781 taaagatata ccaaaatcgg tgcagaaatt tatggaagat atcacacaaa aatgtgggga
    24841 tatccatgcg gactgggcaa agaattttac agcagcattt gccaatactc tgttgacaac
    24901 agtcaaaaag caaaatgacg gaaccacctt tttattgacg ggagacattc cagcgatgtg
    24961 gttaagagac tctactgcac aagttcgtcc ttatttagtg attgcaaaag aagatgagga
    25021 attagctgac atgatcagcg ggttagtcaa aaagcaattt ttttatatca atatcgatcc
    25081 atatgcgaat gccttcaacg aagaagctaa cggtgctggc caccaaacag atcatacaaa
    25141 aatgaacgat tggatctggg aaagaaaata tgaaattgat tctttatgct acccaataca
    25201 gttggcctat cttctttaca aaaatacagg aaaaactgat caattcaatc aatcttttat
    25261 tgaaggtatc aaaaaaatct tggacgtgtt caaaacagag caagatcatg aacactctcc
    25321 ttatacattt gtacgagaca cgacaagaaa agaagatacg ctgatcaatg acgggcgagg
    25381 tgcaaaaaca gcttttacag gaatgacatg gtctggtttc cgtcctagcg atgatgcttg
    25441 ccgttatgga tatctggtac catccaatat gtttgcggtg gtcgtgttag gttatgtgga
    25501 agaaattttt caaacgatac tcgatgataa agaaattgta cagcaaacac agaaattgaa
    25561 gaaagagatc caagagggga ttcagaatca cggacgaacg gttaatcaaa aagggcaaac
    25621 gatttatgca tatgaagtag atggaatggg aaacgccaca gtcatggatg acagtaatgt
    25681 gcccaatctg atcgccgcac cttacttggg atattgttct gaacaagagg aagattatct
    25741 gcaaacaaga agaacattgt tgagtaaaga aaatccatat ttctatgaag gaaagtacgc
    25801 aaaaggaatt ggatcctccc atacgccaga aaaatacgtt tggccgattg cattagctat
    25861 ggaaggaatg acaacgtcag acaaatctga aaaagagcgg atattgaatt tacttgtagc
    25921 aactgacgca ggaacacacc ttatgcacga aggattcgat gtgaacaatc ctgaaaatta
    25981 tacgagagaa tggttttctt gggcaaatat gatgttttgc gaattagtca tggattactt
    26041 tgatattaga gtagaaaagt aggaggtatc gtaaatgaaa aagaaagtat atatcatttc
    26101 tcatagccac tgggatcgtg aatggtacat ggcttacgaa cagcatcaca tgcgactgat
    26161 tgaattgata gacgatctac tagagctatt tgaagttgat ccgtccttca acagttttca
    26221 tttggatggg caaacgatta ttttagatga ctatcttcaa gtaaggccag aaaaaagaca
    26281 ggcaatccaa caagcaatca atgaaggaaa attgagaatt ggaccatttt atatcttgca
    26341 agatgatttt cttatcagct cggaatcgaa cgtgagaaat atgctgattg gcatggaaga
    26401 aagccgtaaa tggggaaccc ctgtcatgtt aggctatttt cccgatacat ttggaaatat
    26461 gggacagacg cctcaattaa tgaaacaagc tggtatttca gcagcagcgt ttggccgtgg
    26521 tgtaaaacca attggctttg ataatcaagt tttggaagca gaaaactatt cttcccaata
    26581 ctcagagatg tggtggaaag gccctgatca aacagcaatc tttggtctgc tatttgccaa
    26641 ttggtatagc aacgggaatg agattccagt agaaaaagaa gcagctcttg ccttttggaa
    26701 gcaaaaatta gcggatgcag aacaatatgc ctctacgaac cacttattga tgatgaatgg
    26761 tgttgatcat caaccggtac aaaaagatat atcaaaagca atccatctcg caaatgaact
    26821 gtttccagat tacgagttta ttcattctaa ttttactgac tatctggaag cagttcaaaa
    26881 agatgtgcca gaagacttag gctcagtaga aggagaattg acaagtcaag aaacggatgg
    26941 ctggtatact ttagccaata cagcatctgc tcgggtttac ttaaaacaat ggaataccaa
    27001 ggtccagcga cagctagaaa atattacaga accacttgcg acgatggctt atgaagttag
    27061 tggaaactat ccccatgatc aattagatta tgcttggaag acattaatgc aaaatcatcc
    27121 tcacgacagt atttgcggtt gttcagtcga ttctgtccat cgggaaatga tacctcgttt
    27181 tgaaaaagca gatgaagttg gaaagtatct tgcacaagat tccttagaac agctgaccgc
    27241 agcaatcgat acgaccggat tcccaaaaga cagctttcca tttgtcattg taaatactgc
    27301 aggaatggat aaaactggtg aagcagaaat aaccatcgaa ttagaaagaa aaagattcgc
    27361 tgaaggaata cctgaacaac tatatcaaga gttagaaaat ttgcctaaac gtaagtatca
    27421 tgtagaaaca aaaagtgggg ccactatacc agctatttta tctgaagaaa ctgtccaatt
    27481 tggttatgat ttgccgaaag accgtttccg tgtgccatat atggcaagaa tgatcaaagt
    27541 gactttacca ttagaaaaca tgccagcatt ttcttgggaa acattcgcgc ttgtagaagg
    27601 ggaagcgaaa gcagaagaaa aggaaacaat gattcatcag agtggacgaa tcatcgaaaa
    27661 cggccctcta catttgacga ttgaaaaaaa tggtaccatt acaatggaag atcgcaaaaa
    27721 caaacgaaag ttgaataatc tgcatatttt tgaagatatc ggcgatatag gaaatgagta
    27781 tatctttaaa caacctttct gtgatcagcc aatcctatcc agtaacaaag aaaactctga
    27841 agtaaaagta ttagtagata caccggaaat agcaaaaata agtattctac aggaaatgga
    27901 aatccctgtt tctgcagacg agcgtttaga aaaagaacag cagatggttg tggaatttcg
    27961 ttatcgaaaa gcagaacgat ccaaagaaaa acgaatcctt caaataaaaa caatcatgac
    28021 aatcagaaaa gatagtaaaa aaatcgactt tgaaacgact ctcgacaatc agatgaaaga
    28081 tcatcgctta cgtgtcttgt ttcctacaaa gttacatgtg gaacatcacg aagcagatag
    28141 tatttttgaa gtggtgaagc gcccaaacca tgtgtctaaa agttgggaaa accccacgaa
    28201 tccgcaacat cagcaagcat ttgtcaatat tcatgatgaa gagtacggtg taacagtcgg
    28261 aaactttggt ttgaatgaat atgaagtaac agaagacgga caaatcgcag tgacgctact
    28321 tcgcagtgtg ggagaactag gcgattgggg atattttcca acaccagaag cacagtgtct
    28381 aggtgagcat cggttcaatt acagcattga actacatgga ccagaagaaa aattctctac
    28441 ttatttgcat gcatacgcag cacagattcc tttttccact caacaaatca aacatcatga
    28501 aggaacattg atttcaaaac aacaatattt aacgataaaa agtgaaacgt ttgcaattac
    28561 agctttgaaa cgcagcaagt ttagtgataa agtagtagta agaggtttca atatgtctag
    28621 tcatttagaa aaattggaaa taactaaaga caatggaaaa actgtcatat tgaatctgct
    28681 tgaagaacca acgaagcaag cggttgtccc aataatccaa ccttatgaga ttcggacaat
    28741 cggattcgag gaggaaaacg aatgtatggc ggaatagaag caggcggaac aaaatttgtg
    28801 tgtgcggttt cagatggtgg agaaatttta gaaaaattaa gtatccctac cacaacacca
    28861 gaagaaacat tggatcaggt atttgaattt tttgatcgtt atgaattgaa gggaatcggg
    28921 attggctcat tcggcccgat tggtatcgac aaaacaaaag ataattacgg atacgttttg
    28981 gcaactccca aaaaagggtg ggcacaattc gattttcttg gcacaatcaa ggaacgctac
    29041 aatattcctg ctgcttggac aacggatgtc aatgctgctg catatgggga attgaagcaa
    29101 ggagcagcac aaggaaaaaa tagttgtatt taccttaccg tgggaacagg aatcggtgca
    29161 ggtgtcgtga tcaatgaaga aattttttca gggatcgcac atcctgaaat gggacatatt
    29221 tgggtgaaac gccatccaga tgaccattat gaaggtactt gtccttatca taaagattgt
    29281 ttagaaggat tagcagcagg accgtctatt gaggcacgca cagggatcaa agggcaagat
    29341 ctgccgcaag atcatcctgt ttgggctatt caggcttatt atattgctca agcactgatc
    29401 aactatacgt tgacgttagc acctgaaaag attattttag gcggtggggt aatgaatcag
    29461 gatcatctcc ttcaaaaaat ccgtcagcaa tttgttgaat tgatgggtgg ttatatggaa
    29521 acacctcaag taagtgaata tatcgttcgt tggggactgc cgaatgaaag tgggattatc
    29581 ggtagtttgc tgttagcaga acacgaacat caaaagtaag cagacaaatt acacaaaaag
    29641 aacagagtct tatcattatc tgctgataag actctgttct tttttatttc tattcccata
    29701 atccaggtaa agctttaccg actatttttt cttgagtaaa tggatggatc atgtgcagtt
    29761 ctaatgcatg gagcatcagt cgttcagctg ttctattttg gtagagaggg tctccaacga
    29821 tcggatgtcc cttatgagct aaatgaactc tgatctggtg tgtacgtccg gtttccaaaa
    29881 cacaatagac ttgtgtttgt tcagaaagta ctttgttgac agtgacatgt gtcaaggcgc
    29941 tctgaccatt tttatcatct acgacccttt ttctccgatc atggcgatct cgtccaattt
    30001 tattggtgat ggtcatatct ttggcaattt ctccccatac gatggcttga tatctccgat
    30061 agatcatttt ttgttccaac attcttccaa gtatcggcaa gacaaatgga ttttttgcaa
    30121 ataaaacggc accgcttgtt tctttgtcca agcggtggac aacgtaaggt cgttgctgtt
    30181 tagtgtcgag ataagcagct aaatgattga gtaaggtact gttttctgtc ggttcatttg
    30241 gatgagtctt cattcctgca ggcttatcca ctataatcaa atgctcatct tcatataaaa
    30301 cacggatgtg cttcgcatct cctaattgaa cttcttgata attataatct gtttcttcga
    30361 ataacaatgt gatctggtca ttgcccttta cttcatgatg gaacaaagca ggttgttgat
    30421 tgatccaaac gtttttacgt atacgcaaaa agtgtcgaac ctttctagga actaaccatt
    30481 ccttttcaag caagtcgcga attgttgttt caggatggtt cataggtaaa gtgatcgtga
    30541 ttttcacaag tgtactcctt tcagtgcaat cgcagactaa ttgtaccatt tttaaaacat
    30601 atttaagaaa aaacttacat ttttctgttc attcttatgt tactctactt gcactaacgt
    30661 aaaaaaacat attgaactac aacttaagca ggaagaaaac actctttcac tatggtaaaa
    30721 taagacgatt gaatcaaata gacaggagaa gaagcaaatg gattttcaaa gcattttaga
    30781 aaagataaaa gctgctttga tcagtttttg gcgttggatc agaccatatc tcggacaatt
    30841 ccatcgatgg cgaaagcgca tctggaaaaa atatcatgtg aacaaattga ttttgctgat
    30901 tggtttgatc tgtgtcttag tgacaagtat ctacctcttt attttagcaa aacaagcaaa
    30961 tgtcgaaacg ttaaaatcag gattaagcca atcgacagtc atttatgata agaaaaacga
    31021 agaagctggc acactgtacg cccaaaaagg aacatatgta gaattaaacg cgatttctcc
    31081 ctatatccaa gatgcagtaa tctcgacaga agataggaat ttttacgagc atcacgggtt
    31141 tgatatcaaa gggattgccc gtgcagcagt ccgaatggtc ttgtctggcg gaacatcagg
    31201 gggcggagga agtacgatca ctcagcagct tgccaaaaat gcgtatctga cattagacca
    31261 aacgtttgat cgaaaagcga aggaattatt tttggcaatc gagatcgaaa agaagtacag
    31321 caaagaagaa atcttgacca tgtatcttaa caatgcctat tttggcaacg gggtatgggg
    31381 tgtccaagac gcttccagaa agtattttgg agtagatgca acgaatgtta cgctgtctga
    31441 ggctgctact ttggcaggaa tgctgaaagg tcctggtatt tataatccga tcgatcaccc
    31501 aaaaaatgcg aatgatcgga aaaacacagt actaagtgta atggaagaaa acggaaaaat
    31561 cacaaaagaa caagaacaag cagaaagcca gacagatatc agcgcgtatc ttaatgacac
    31621 atacgataat tcagattctg gttatcgtta tccttattat tttgatgcag tgatcgatga
    31681 agcagttaac gagtatggtc ttgatgaaga agatgtcatg aataaaggct ataaaatcta
    31741 tacagcttta gatcaggatt atcaaaagca attagaagct acttatcaaa acagtgcatt
    31801 attcccagca aatgcttcag atggtgccat ggtccaatct gcttcagtag ctttagatcc
    31861 gaatacaggt ggtgtacaag cactagtagg acgaagagga gatcatgtct ttagaggatt
    31921 cagctttgct acacagatgc gtcgttcacc aggatcaacg atcaaaccat taagcgtata
    31981 tacaccagca ctggaagctg gatacaagcc ttccagtatc ttgaaagacg aaccgcaaag
    32041 ttattacgat gcgcataatt ttgacgggac ataccaagga gaagtaccga tgtatcaagc
    32101 tgttgcacaa agtttgaatt tgcctactgt atggcttttg catgagatcg gtttacaaaa
    32161 aggatatgat aaagcagaag aattcggcct gcctttagca aaatctgata agtattatgg
    32221 cttagccctt ggtggactgg aaaaaggagt atctccattg atcatggcgg gtgcttacag
    32281 tgcatttgcc aatgatggtc agatgtatac gccgcatctt atcacgaaaa tcgttgattc
    32341 gactggagcg gtgatcgtcg ataacacaaa caaaaaacca aaacaggtca tatcaaagga
    32401 aacagccgat gaaatgacca gcatgcttct tggtacattt tcaaatggaa cagcggctgc
    32461 tgcgaatcct gcaggttata cgatagcagg gaaaacagga accacagaaa ctaatttcga
    32521 tgccacaaaa gcaaatgacc aatggatgat cggttacacg ccagacgtag tgatttcgac
    32581 atggatgggt tacgaagaat ccagcaagct gcactatttg gaagggacaa gtggaaatgt
    32641 tgtcgggaaa gtcttcaaat cagcggcaga aggcatcctt ccgtatactt caaaaacagg
    32701 atttagtgta gcagatgcct atgccacagg aggacaagtg gtagctgcag atcaagttgg
    32761 aaacacagga aattctaatg gagagtctgg aaattggcaa gataacttga atcaatatgg
    32821 tgaacaagca aaagaagggc tgaaaaactt cggcgatatg gtgaaagaag gcgttcaggg
    32881 aattggtgaa gcggctaaag acctctggcg gaaatatcaa ggagagtagc ccctttgaaa
    32941 acgaataacc ccatgttaca atagagagta actactaaaa gaaaagaggg cataacatgt
    33001 caaacatcta cgatagcgcg aatcaaatcg aacgtgagat ccgtgaatta ccagaattca
    33061 aagcgttgaa agaagcgtac gagaaagtac aagcaaacga agaagcacac aaactgttca
    33121 aagacttcca agcgatgcaa atcgaattac aagaaaaaca aatgagtgga caagagttca
    33181 gcgacgaaga tgcaatgaaa gcacaagaaa tggctgtgaa aatccaatca gaagaagtaa
    33241 tcaatgactt gatgcaaaaa gagcaaggct tcagtacaat catcaatgac ttgaaccgta
    33301 tcatcatgac accagttcgc gacctttaca gcgaataaaa ctattttatg aaacaacaga
    33361 gggtgtgaaa gagacgttcg gccttgagcg atgacaaaat tgcttcttat tgccgatagg
    33421 ctgtctcttg aacaccattt accaagaggt cgtgagccta ccgtttaact ctgagttaca
    33481 aggaacaatt tcaaaaaaca gcttctcatg tttgatgact attgtgactt gtgaccgagg
    33541 agttggcagg agaacaccgt ttattcagaa ataggagcta cgacaaaagt cttgtcatag
    33601 ctcctatttt ttgtcattca tttttcaagc ggtagaaata gcctttttga gctaacagtt
    33661 tttcgtaagt acctatttca acgatttttc cttcatcgat cacaacgatt ttatctgcct
    33721 ctttgatcgt tgaaagccga tgagccacaa taaaagtagt gggtgtttct gtcaggtaat
    33781 tcagggcttg ctggattttt ttctctgact ggttatctaa agctgaggtt gcttcatcta
    33841 gcaaaatgat ttttggctga cgtatcaacg ctcgtgcaat ggagatacgt tgcttttggc
    33901 caccagacag cttgttgcca tgttcgccta ctaaggtatc cagaccatca ggaagctggt
    33961 caatcagtga agaaagttgc gcagcttcga tgacttcatc taaacgttct tttgatacgt
    34021 ttttcaagcc ataagtgatg ttctctttga tcgaagcgga gaacaacaaa gtggtttgag
    34081 gaacaacggc taaataattt cgcacacttc gcatatccag ttcatccaaa ggctgatcat
    34141 ctagaaaaat ttttcctgaa gtcggctgga taaatccaat caataagtta aggagtgtag
    34201 attttccaga gccagatggc ccaacaaaag caattgtttc tccagctttc acctctagag
    34261 aaaaatgatc gataatcggt ttgagtgagt ccggataaag aaaagaaaca tcctcaaaac
    34321 gaaaatttcc atccaaatgt tggatttttt tcttaccgtg ataagtttct acatcgccag
    34381 caatcaacag ttcgccaata gaagtgatag attccatgcc ttttgaaatc gtaggaatca
    34441 gcgtgatcat tccagaaacg gaattgacga tcgtcgtgaa atacgtctga tacatcacga
    34501 catcgccggg ttggatgcgc ccttgtaaag ctaatatccc agtgaaaatc aaacaaatca
    34561 gctgaaatat ctgaaaacta gcccagctga ctgatccgaa aacagattgc aggatatcta
    34621 agtggaatcc tttttcatag atttgagtaa aatgcttatt taagcgagtt gtttcgtgtt
    34681 tttctaaccc atgagctcga gcaatcggtg ctaattcgat cacttcgatc acttttgcag
    34741 aagtctcttc catttcttgc ctgaagtctg agttggactg tctgatcctt ttacggaaaa
    34801 agagagtaac gaatgcggcg agaggaacag tcaataagaa aaacatgaaa acaacaggac
    34861 ttttataaag cgtgatacct aaagctacga ataaattgac agcgatattt aatccgctga
    34921 caaatacttg agaggacaac gtttggatag cttctacatc acggatgatc tttgactgga
    34981 ttcgtccaga ttgcaattct ttttgataag gaatagatag ttcttggatt ttcttgataa
    35041 gggtcgctct tagtccagct tctacttgac ggatcgaagt gctatggtat tttacatgaa
    35101 aataattcgt caatatattt tgaccaatca gacaagccat caaaaaagcg ttgaaataaa
    35161 tggcctgcaa ctgagaagaa tctttcgatg aagctgcatt gattacattg gcaatagcga
    35221 tcggcattaa ccaagatgga agatgtttga taataaaaaa gagtcctgac atggcaaaac
    35281 gccaataatt tccctgataa agatgcagca atgtctgaaa agcatttgca tgatattttt
    35341 gataactttt ctgtattcgt tcctccataa tcttctcctt aacaatcttg gtaaataaac
    35401 tgcaagtgtt ctattgcttc aggaacataa atctcaggag tagcttcaag agtggcgtac
    35461 attagaggac gctcatattt gatataatgc agtaccgggc ggaaatctaa acagcccttg
    35521 ccaacaggta ccatgcggat ctttccattt tccatgatat agtctttgag atgaagcgct
    35581 gtaatataac catgtaaatt gtccaaggca cctcggatca ctttttcctg atcagcatga
    35641 ttttctttat gcatcaaatt cgcacaatct aaaatgattt ttaaatttgg tgaagctact
    35701 tcatcgatta aacgtttagc taactgatag ttatagattg gatgattgat ccctgcttca
    35761 acagcaacag ttacgccaaa attttctgca tgagcgacta attcaatgat agaatttctg
    35821 gcgatctgat aagcttcttc agtaaaattt tcttttgtgt aaccgacaga gacactaccg
    35881 gtttccgtag caatcatctt ggcttgatag gcagagcaca gagcaatttg ctgtttgaaa
    35941 gttgccaatg cttgtgcacg aacttcttga tttttgctgg ataggttgat atagcatcct
    36001 aaaatggaaa gttcgatatt gtttttttgg aagtattcac caaaataggc agcactccca
    36061 agtgtcatgt cagttaattt aagttgttca ggaaatgctt tttgtggtgc aaattggata
    36121 tgggacaagt gaagctgtga tactttttga acgatttctt cacgatttcg aacatctaaa
    36181 tcgtgggcac ggatgcctaa atttaatgga aacatctcaa actccttttt gtaaataatt
    36241 agcaagaggc agacgggatt cttttatcaa ttcaacaatt attcgggcaa ctttatcagc
    36301 gccttctgga ctaaagtggg tattgtcttt tagtccttct gggtaatttt tacaagtatc
    36361 aggtataaga tgcaggtaga atttttttgt ctcttctttt gagaaggtct ggaacaattc
    36421 ttgtgatctt gagaacacat ctaaaagagg aatatggtgt ttctcagcaa atgcacgcat
    36481 cgcttttgga tagtctccaa gtatatctgg attcaatgtt ccgttttcta agtaatctcg
    36541 tcgcgtcaca gatgtcagta agaccatttg gacgttcgct ttttttgcgc attcaaaaaa
    36601 tatctgcaga ttttttaaat agctaccgaa gggaagcgta cctctttctt cttggatttt
    36661 ctggtcgtta tgtccaaatt gtacaaataa gaaatcattc ggctgaaact gtgaagctag
    36721 acgggctaac cttccttcct ggataaatga tttggtgctg cgtccattct ttgcttggtt
    36781 attgatctgg atctcgggtg aaaaataagc agagattttt tctccccaac ctgtctcggg
    36841 acgcttgttt tcatcttttt ctgccgcagt agaatcaccg gcaatatgga tagtaggcat
    36901 gttatctctt ctttcataaa ggtttatagg caatgaagca gaacagcaag agaagaagac
    36961 ggagcaaatt tggtccgtct tcttctctaa aacgtggata aacggattcc gttatttcac
    37021 tatcctgttt ttgattcgtt actgttacta ttaatcaatt aggcaaaaaa gccaaagtaa
    37081 tttttagcat ttgtataact aatcgcttga actagacttc ctaaaagttg ttcatcttca
    37141 ggtgcttctc ctcgcatgac catttcgcct aaaaattcac aaagaacacg acggaaatat
    37201 tcatgtctag tgtaggacag gaaacttctt gaatctgtca gcatgccgac aaaattcccc
    37261 aaagcactac catcagcaaa ttgtgtcaat tgatcgcgca taccagctcg agtatcgttg
    37321 taccaccatc cagaacctaa ctgcagtttt ccattctgtt ctttttggaa acagcccatc
    37381 aaagctaaaa tcgcaggata gtcattcgga ttcaatgaat aaaggatcgt ctttggcaac
    37441 tgatccgttt cttctgcacg gttcaataat ttttgcagag gaatagtcaa agaaagatca
    37501 ttcattccat catagccggt atcgggccct aatttttcca acatttgtgt attacagtta
    37561 cgataagcat ggatgtgcag ctgcatcgtc caattatgag aatgatagaa gtgggtcaaa
    37621 tgtatcagtg tttctgtacg ataagcatcg atttcatctg aagataatag tttgttagct
    37681 cgtgcttttt gaaaaatctc ttctaatact gtttcatccg cttctttata gcgtaagatg
    37741 tctaaagcgt ggtcggaaac acgacatcca tgttgatgga agtattctat ccgctgccct
    37801 aagacttcta tcagttcttg ataggtggtg atcgtttggt cagctgcttc ttccagtagt
    37861 gtgacccatg cattaaatcc ttctttttca atattgagtg ctttatctgg acggaatgaa
    37921 ggtagaacct tcaaatctgg ttcttcatga gcaagcaact gatgatagtg caagtcgtct
    37981 gcgggatcat ctgttgtaca aatcacttct acattcgatt tttttgcgat ttcccgacgg
    38041 cgaaaatcag gagctgccaa aatttcattt gcttgtgtcc aaattttctc tgcattttct
    38101 tcatttatca acaagtcaat accgaagaaa cgcttcaatt caagatgtga ccaactgtaa
    38161 agcggatttc cgataatttt tggtacggtt tgacaccaag ctaaaaattt ttcaaaatca
    38221 gaagcatttc ctgtgatttt ttcttcaggc acgccgcaag ctcgcatcaa gcgccatttg
    38281 taatgatcgc ctcctaacca agcttctgtc agattgctga aattgttgtt ttcgtaaatt
    38341 tcttttggat ctaagtgaca gtgataatca ataatgggca tgttttttgc gtaggaatgg
    38401 taaagctttt tcgcccaatc gtcttttaat aaaaaatcat cagataaaaa cataaatctt
    38461 ccttctttct ttttatactg ttttatgaaa atcaaagtgt tactccgttt ttaaaaatgg
    38521 caatttctcg aacgtcattt tgttcatttt tcgtttcttc tccactagct acagcgatga
    38581 ttttttgaac aaacgattct aagattactt ccattggttg ttctaataag acgcctgcat
    38641 taaaatccat ccaatgacct ttgcgttcaa aaagagttgt attcgtagat accttgaccg
    38701 ttgggacata tgagccaaac ggagtccctc ttcctgtggt aaacaagacc aactggcaat
    38761 cggatgaagc aagagcagag gcagctacaa gatcattccc gggagcttgc aataaactaa
    38821 gccctggttt tctgattttt tcgccatatt gtagcacatc aacgacagga gagcttcctg
    38881 atttttgcgt gcagcctaaa gacttatctt ctaatgtagt gatcccacct gctttattac
    38941 caggagatgg gttttcgtaa actggttccc cgtaagacaa gaaatactgt ttgaagtcat
    39001 tgatcaagtc aacgattgag tcaaaaactt cttcattttc cgctcgtgcc atcaatactt
    39061 gttctgcgcc aaacatttct ggcacttctg ttaagatcgt gctgcctcct tgagcaatca
    39121 agtagtcaga aaatgcacca agtaaaggat tagcagttat tcccgataga ccatcagaac
    39181 cgccgcattt caaaccgaca ttcaacttag agagcgggac tgatatgcgc tggtcatttt
    39241 ccgccgctgt taaaagctct tctaatagag ccacaccttg ttcgatctca tcgtaaacat
    39301 cttgagccac tagaaatttc actcgttctt catcatattc acctaaaatt tttttgaatt
    39361 caggaactgt attgttctca caacctaatc caaatactaa aactcctccg gcattgggat
    39421 gatttactgc gtccgctaaa atttctcgag tattttgatg atcttttcca agctgcgaac
    39481 agccataagg atgctttaaa atcgtaatat ggtcaaactg tcccagatct ggatgttttt
    39541 ccttgaactg tttgacgatc agttcagcaa tgccattcac acacccaacg gtaggtacta
    39601 aaaacaaatc attacgaatc cctacttttc cattttttcg caagtaacct tgaaatgttc
    39661 ggttctcaaa aaggtaatga cttggatgga catctttttc atatcgataa tccaattcac
    39721 cagaaagatt ggtttttaca ttatgagtgt gcagccattg accggcagtt acgtctgtcg
    39781 tcacatgacc gattggatag ccatatttga tcacgttgtc tccagctttc aaatcaccca
    39841 atgcaatctt atgaccttgc gggatatctt caagagtggt gatcgtttgc tgatcaatcg
    39901 tcagttgtgt ttgttttgga ataggggtta atgcgacgac cacactgtct cgtcgattta
    39961 atttcattgt tggttgcagg gtttcaagca tggaccatcg ttcctttcat ttcttgtaat
    40021 actgaccgga cacctttttg atcgatcttt gcagctattt cttgaactgt atctgtcaca
    40081 ttcggtattt gagacaaatc ttctccccaa agcgcagcgt tttgcaataa tcgaggaata
    40141 gctgttccat tatcagacca agcatcagta aattcgctta tcgtcttttc atcatcatgt
    40201 ggctttactt gatcgcctcg atacataaga agtagcgcag ctagtgaaac agtgattaac
    40261 ggtggtacct gattttgttc ttcgatatac ttcttgaaca ctggaagcag acgggtgctg
    40321 aactttgaaa cactatttaa tgaaatcgct tctaatttgt gatgggcaaa aggattcaag
    40381 aaacgttctt tgatttggtc agcataaatg gctaattcat ctttaggtaa agaaagcata
    40441 ggaatcaatt ctagattgaa taactgatca acatatgcgg agaataaagg atctttcatt
    40501 acttcttcta cagtttccaa ttccgccaac aaagcaagag ggaccatcgc tgtatgcggt
    40561 ccattaagca aatgcacctt acgttcacga taaggagtca tatcatctgt gatgatgaca
    40621 ttcaagccag cctgtttgaa tggtagttga ttctccaatt ctttaggccc ttcgatcacc
    40681 caaagcatga atggttctgc tttgaccatc aattgatctt catagttatg ccgttgattg
    40741 aaaacacctg catcttcgcg aggataacct gggacgatgc gatcaactaa actacaacag
    40801 aaaacatttt ctttttctaa ccactcaaca aaagcaggtt ctaaatccca tttttctgcg
    40861 tagcgtaaaa tgatttcttt tagacgttcg ccgtttctgt caatcagttc gcaaggaatg
    40921 atggtaaagc cagctttgtt taatttgaaa cgtcggtata aaaaggctgt cagtttgccc
    40981 gggaagctct gtgggggagt atctgttaaa ttatcagtct ccacgaattg gattcctgcc
    41041 tctgttgtat tggagacgat ataggccaag tcgtcatttt ctgctagaga tagataagca
    41101 tcccattcat cataaggatt gatcatttgt tctactacgg tgataatctc ggaagtatca
    41161 acgatttcgc cattgctgag tccttgtaaa atgaccgtat ataaattatc ttgctggttc
    41221 atcatatttc caagaccttg ttctaaaggt tgaatgattg caacattacc tttaaacaat
    41281 tgttggttat tcagctgctg aatctgccaa tcaataaatc cacgcataaa attgccttca
    41341 ccaaactgaa gaacttttac aggtgcttcg ttttttttca ctaattcttt tgtcagtttt
    41401 ttcatataaa cttcctttct gtgttatgca cacgttaaca tttttatata aaattacttg
    41461 tagtttacaa gtaattgatc gactcacgaa ggatcaacaa ggtggagagc tcaattttag
    41521 attgttcgat cgtcctgcct tcgatcaaat ctagtaaaag ctttgttcct tcttgacaca
    41581 tttctttcaa aggcttacgt acggtggtaa gcggcggatt gagataggag acgactggag
    41641 aatcatcgaa cccgatcaga gaaatgttct ggggaacacg gaggccagct aaatgtacag
    41701 ctctcaatgc accaatcgct atgtcgtcgt tgccgcaaaa aaccagagta ggcaggtcag
    41761 aaagtgataa taggtattcc atgttttgga ggccgctttc taagctgtaa tctcctgtta
    41821 aaaaataggc tggattgaca gggatgctcg ctttttttag acttttcaat accccttttt
    41881 cccgttcttt tgtcgaacga aaatttttct ttccgccaat ataagcgatc ttcgtatgtc
    41941 cgcatccaat accgtaatct actgcctgca taacaccggc cgcatcatcg gcagtgacgt
    42001 tgataaccgc tggatcattg atgtgacgat tgacaacaac gaaaggaaat tctttttctt
    42061 tgagatagtc gatgaaaggc tgatcatcat cactttgact cataacgatc agtccatcgt
    42121 agcgttgcag gttgatttct gttaaatcaa caacatcgat actttcaaca gataaactgt
    42181 aatttgtgtc taatactgaa tggatgcctg caatggaatc tgctaggaaa tttgatgaag
    42241 ttcctttatg caaacttgag aaaaatagtc cgattagata ttttttttga ttcactaaac
    42301 cttttgcact atagtttggc gaataattca tttccttagc tagttgtcgt attttttgtt
    42361 ttgtttcatt ttttattaaa ctgctgttat tcaaagcacg agaaactgtc gtatgagaaa
    42421 cgccagctgc tttagcgata tctttgatcg ttaccattcc atcattttcc ttactttttc
    42481 actttttgtt aacgcattca tcatattacg ataactacga taagtcaata gatctttgat
    42541 atgaaaagat tgcacacgtt aaaaattact tggattttta tttttaatta tgctattctt
    42601 gaaagcgggg aatgctcatt taattagatg agtatcaatt ttacagaaaa atgaaagcct
    42661 tttattttaa aaggaggaga ggaagaaaat gaagaaaagt acagtatttt ataaaatatt
    42721 tttaccgatg tttttattag gagccgtact tgtcatagga tttagtttat tcatttacca
    42781 gaatacctat gaatcgatcg aatcgagtta tttaacagac aaaaagaatt tgctcaggca
    42841 agttaaaact aacgttgaat ggaaaattag aacgattgaa tattcgtttt ctacgtatgg
    42901 ttcgaccaaa aatttctcgg acatattcaa gcatccgctg acatatacag attactccac
    42961 ttattctgaa atcaggaaag aactaaattt tatagaaacg attgttatgg atgataataa
    43021 ttatgattta gtcagtttgg ctggtaaatg gggagtaatc aatggatcgt tgagtcaact
    43081 gaccgaagag gaagttgaaa agtatcaaca gaagtacata aataacaaaa ataatttatt
    43141 ttggcaaaag aaaaacaaag gaatcgaaat ggtgatttct ttgccaatgt ttgaaaaaga
    43201 aaaatatgca ttgggaattg ctacgataga gaaacataca atagaacaag ttgttggtga
    43261 aagtggagaa gacatacttt ctattgaaaa cgaagttggc aaccttttta ctactcagac
    43321 agtaaaaaat aaagagcaac caactgtatt aacggacgtg gatctagatt acaatcagct
    43381 gaaagtgata agagaaaaag ataaaacgta tatagtactg aaatcagatt ataataattg
    43441 gatttacaga ttagaagttg actctagtgc aattggcgca atgatccgca atctgagaat
    43501 cgggctagtt gcagtgtctt taacactggt aggactcatt ggtcttcttt cctacttatt
    43561 ttcggacaga tttgcccgtc cgatttctca aatacaggaa cgtctgaatc ttaaatcaaa
    43621 aggattcagt gggaaagaac tagatttggt cgctcaatca gtcagtcgga tcataggaga
    43681 aaaagaagcg ttaagtgcac acttagttac ccaaaagcca cagctggaaa cgctatttgt
    43741 acttagttta tttagaaatc gagtagaaag gcgagaacta gatcagcggt tgcagcaatt
    43801 tggttatagt tctcaaaatg actgctatta tacagctttg gttcaaatcg atctgttaga
    43861 agatagtcac ggtggggagc gtgatttgct acttttagcg atcaacaaca tgatcacgga
    43921 aattgtgcca aaggaaaatc gaatgctgcc gatcgttttg aatgaagaaa tgcaagccac
    43981 tatttatcga atggataaag atgatgcaga agcaagcaaa aaagtcatgg agtattgccg
    44041 actcattcaa aaacgtgtaa aagaatactt gaatttaact atcagtatag gcatcagtaa
    44101 ccggttcgaa acgctgaatg aaagcaagca atcggttgat cgggcaaaag aagccctgta
    44161 ttatcgtgta aatactggtc caagttcaat tattttttat caggaaatcg ttcctgctgc
    44221 tcatgaaaaa acacttatta gatatccgat agaagaacaa aatcgattgt ttgaagccat
    44281 tcgttctgga aatcaggaag tgaagaattt agtacatgaa ttgattgatg cattgtttgc
    44341 acaaaataaa aatcctttga gtcgggaagt agtttcggtc cgcttgatca atgaactcgt
    44401 tcaattagga cagttattgg gagtagattc aaaaaacttt gataacatga aacaaattta
    44461 tgtaaaagca ctgaacaatt atcatcccaa agaactagaa aaacttgttt tagaacaatt
    44521 agttctgcca atcacagaat gctctcaagc aatcactgat catgaattta aaaatttgtc
    44581 ggagaatatt atgcatatcg tctacacaga atatgatcgt gatctgtctt tagatgtgat
    44641 cgctgatagg ttgcattata accctaacta tttaagtaat gtatttaaaa aggaaacagg
    44701 agaaaaattt ggtgattttg ttcaaaatca tcgtttagag gtagcaaaaa aatggttgaa
    44761 agagactaac ctctccgtaa aagagattgc agaaagattg caatatcgaa atccgcaaaa
    44821 ttttattcgt ttctttaaaa agaaggaatc gattacgccg ggagaatatc gaaaaaaata
    44881 tttgtgaatc aagaggctgt ttttcttgtg gactgattca agcaataaaa gaagttagaa
    44941 taaccctagt atttgtattt atggatagtt aaatttcaag gctaagcacg caaaaagaac
    45001 tgtgacaaaa gtcttgtcac agttcttttt tacgaataaa tggcgttcaa gagacaggct
    45061 atcgacaata aggcataatt ttgtgaaata tgggaagcta tttttcaaaa tcgcttctta
    45121 ttgctcctgt gggttactcg tcgcaatgtt tgtgagagtt tttatcatcg ctcaaggctg
    45181 aacgtctctt tcacaacctc tgatacacgg tgttccagga gtagattctt cgaaaaataa
    45241 gccgaaattt cacaaaaatt taagaagcaa ttttcgtaaa tgccttctta tttcttgaag
    45301 ctgaccactt ctgacacaac taccattttg cgttcagtac ataatcaccc tttgacagaa
    45361 cctacgagtg ctcctttgac aaaatatttc tgaacaaaag gataaacaat cagcataggc
    45421 actgttgcaa taacgataac agccatttta actgtttgtg ctggtggaat cacatcaacg
    45481 gcactacttt ctgcttgcat cccacttgat acaatgacga tttggcgtaa aagaatctgt
    45541 atcggccatt tagatgaatc gttgatatac aaaatagcag tcatataagt gttccagtaa
    45601 gtaacagcat aaaaaagcga gatagtagca atagacggta acgctaatgg cagcataatt
    45661 ttgaaaaata caccaaaatc tgtgcaacca tccatttttg ctgattcttc caaactatcc
    45721 ggcaaggctt ggaaaaagtt tctcataatg atcatattca ttgcattaac agccacaggc
    45781 aggatcatgg cccagtaaga attgaccagc cctagagaac gaacaactaa gaacgttgga
    45841 atcatccccc cgctgaacaa catagaaaat acaacaagaa agttgacgaa acctcgacca
    45901 aacaaatact ttctggaaag accgtaggcc atcagtgaag ttgcacacat actgacgatc
    45961 gttccgacac ctgtaacacc aatcgaaaca gcaagtgctc taaaaatggt cggcgtagaa
    46021 agaatgtagc gatacgcgtc taaagaaaag gtagtaggaa aaaggataaa ctttttcgcg
    46081 acgacttctt gtgtagaagc aaaagatgta gcgatgatat ttaaaaaagg aacgatacag
    46141 atcaaagcta gcaaaattag aaacgtattg ttgaaaagtg taaaacttct ttctcctata
    46201 gagactttct ttttcatata gataggctcc tcctcaaaat aaattaaatg tttctgtttc
    46261 tatatgttca atttatcatc ggtgaaagat tacgtatata atcatttcct atgctaagtg
    46321 tcagatagaa aaaaatagaa ggtttgctat gcgtagttta tttgtgaaaa aatacacttt
    46381 atcgttttgt atagcacaaa aatcattgct atgtaagcgt ttttacttac ggtaaaaatg
    46441 attatatacg taattcagat agttatctat catgaagtca taagcagcaa acattcacaa
    46501 aactaaggag gggcttatgg aaagtgtaaa gaaacaagaa ccatttcaac tgacgctatc
    46561 gaaaaaagaa gaaaagctca gaagacgaaa aaaaataatt gcaggaatca aaacgaataa
    46621 atttttatat gtgatgattc tgccgggagt cctttatttc ttgattttta ggtatcttcc
    46681 tatgggggga ctcgttattg cttttcaaga ttatcaacca tttttaggaa taatgggaag
    46741 tccttgggtc ggtttcaaac atttcattcg tttgtttaca gaaccgacat tctttacatt
    46801 attaagaaat acgttgatct tgttcggatt aaatatcttc gtgttttttc cgatgccaat
    46861 cattttgtct ttactattaa atgaagtaac gaacaaacga ttgaaaaacg ggattcaaac
    46921 gatcatttac atccctcact tcatgtcttg ggtaatcatt gtttcgatta cttatgtatt
    46981 tttgaatgtt gacggagggg tattgaatga attccttgca acaatgggat ttgaaaaaat
    47041 cagttttcta acatcccctg aatggacacg cacagtatat atcggacaag tgatctggaa
    47101 agagttgggc tggtctacga tcatctacct ttcagcgata actgcagtcg atacacagtt
    47161 gtatgaagct gcagaaatgg atggagcagg acgcttacgc aaaacatggc atgttacatt
    47221 gccggcaatt cgtccagtaa tcattacctt gctgattcta aaaatcggtc agacattaga
    47281 cttagggttc gagcatatgt acttgttatt gaattcattg aatcgaagcg ttgcagaaat
    47341 tttcgacacc tatatttata cagctggatt gaagaatgga cagttaagtt tcagtacagc
    47401 aatgggattg tttaaagggg tcgtaggatt gtttatggta attttagcta ataagattgc
    47461 caaaaagcta ggagaagacg gcgtttacta agatagaaag agagggaaag atatgctgca
    47521 gtcattagat aaaataaacg gaaggctaaa tcgtatttta cagttggttt atttgaattt
    47581 tctgtggggc ggtttagtca tcgcaggttt gggagttttt actttcggtc ctgcatcgta
    47641 tgcgatggtt gcagtgatta gaaaatggct gcgctcaaaa gaaacgtttc ctttgacgaa
    47701 aacgtacttc acatatttta aagaaaacta tcgtgaaacc ttgctgatga gctggatata
    47761 tggcgccatc gggattgttt tacttgtgga tctttctttc atacacaatt ggtatcttag
    47821 gatcgctttg tatattgctg cgttcatata tgtgctctca gcactctata ttttcccaat
    47881 catggctcat tatgattgga aaggatattt tttcaaaatg aaaatggcat ttttattcgg
    47941 attctcacat cttcattact cattagtgtt gatattaagt atggtaggga tttatctgat
    48001 gatcatccaa acaatgccag gtgttttaac ctttatcggt ggcagtctct tcttttccgc
    48061 agtcacgtgg acagcaaatt ctatattttg ccatttggaa tggaagaact catatacaga
    48121 aaaaacagaa gaaaacaaaa atattattaa aacagtgaag gagaaaattt atgaaaaaag
    48181 caacgctcgt aaaattaggt cttagttttg caggaattct agcacttgcc gcatgcggca
    48241 gcagttcaag taacagttct tcagagacag aagatggaaa agctaaaatc acttggttaa
    48301 atattttgca tcatgcttca ccgcctacag acacgattgt gaacttgatc gaagaaaaaa
    48361 ccgatacgga actgacattc aactggattc ctgatgcttc aaaagaagaa agattaacaa
    48421 ctgcattggc ttctgatgaa ctaggagata tcgttacact tcaaattgcg atgttgaaaa
    48481 actcttctgt ccgcaatgcg ttaaaatcag gcgtattctg ggatgtatca gaatatttaa
    48541 aagactataa aaatttaagt caaatttctg aagatagaat cgaagctgcg agtatcgacg
    48601 gtgccttgta cggcgtaccg atacaaaaag actacgctcg tgctggctta gtcattcgaa
    48661 aagactggtt ggataatcta ggactagatg ttccaactac catggatgag ctttatgaag
    48721 tagctaaaca atttacagaa aacgatcctg atggaaatgg tgtggacgac acagttggtt
    48781 ttggcgatcg tgcgcctagt gatattcgtt ataccagctt taaacttttc acttcttatt
    48841 ttggagcacc aaatggctgg gctgtagacg ataatggcaa attcactcca gaatttgata
    48901 cagaagagta tatgaaagct ttgaattttt caagagatct atttgagaat ggctatttgg
    48961 cacaagactt tgcagttacc caaaagactg atcagcaaga acaatttgca caaggaagaa
    49021 ctggaatcta cactggaatg gtggatatca agaatctgaa gacgatgggt caaggtattc
    49081 aagatgatat ggaattagtg cctgtaaaca agatctcaga tggtgaaggc ggcggttatc
    49141 atgtttggtc agaaggaaat ggtattggcg gcttgctagc atttcccaaa tctcaagtaa
    49201 aagacgaagc acaattgaag aaattacttc aatttgttga tgatctttta gaagaagatg
    49261 tgtataaatt gatgactggc ggtatcgaag gaacgcatta tgaattgaat gatgatggtt
    49321 ctatcgaatt tatcgatatg gatctttggc aacaagaggt gcaaccgtta tcaagctctc
    49381 gtcctagtga agtgacgttc tctttcaaag atacagaccc tgaaaaagaa ttctctaatc
    49441 aattgatcaa agaaaatgaa gaatttgctg taatggatcc ttctgtgcca ttggattcac
    49501 cgacgaacaa tgaagtagga tcagaaattg aaaaaatcgt cattgatgct acggtgcaat
    49561 acatcatggg acagcttgac gaagatggat tcaaaaaagc tgtagaagac tggaaagcac
    49621 aaggaggcga tcgaatcaca caagagtacg aggaagcata caaagcagcg gcacagtaat
    49681 atagacgatt gggacaaata cttcttggta tttgtcccaa atcctatttt aatttttaaa
    49741 ggagagcaaa taatggaaaa ctggtcaaag aaattagcaa aaagtatcat ggaaagaaca
    49801 cctcgcttat atgaagaaaa gtggtataaa ggaaaatggt cttatgacta tggcgtcgta
    49861 cttaaagggt tccaattact ttgggaacga acccaagaaa aaatttattt tgatttcata
    49921 aaagacaata tcgactattt cgtgcaagaa gatggaacga tccgtggcta cagcgttgaa
    49981 gaatacaata tcgaccatgt aaatacagga aagcttttct ttttattgta caaagaaaca
    50041 ggcgaagaaa aatataaaaa agcagcagaa ctcctttccc agcagttggc aaaccatcca
    50101 cgcacatccg aaggagcttt ttggcataaa gaaatttatc cttatcaaat ttggttggat
    50161 ggcttatata tgggttctcc tttttatgct gaatttatcc agaattttag tgaagaaaaa
    50221 gattaccaag atgttttgag acagtttgaa atcagttata aacatctatt cgatccaaaa
    50281 acaaatttgc tgattcatgc atgggatgaa aagaaggtcc aaccatgggc tgatccaaaa
    50341 acaggtctat cccatcattt ttggagccga tcgattggct ggtatttgat ggctgcagca
    50401 gatacctatg aattacttca tgaagaaaca gattgttctt tgctgaaaga aattctagaa
    50461 aagacactgg ctgcattact tccatatcaa gaagaaaaca gcgggacatg gtatcaagta
    50521 acaacagaaa caaaacggaa aggaaattat ctggaagctt ccggcagtag tatgtttgtt
    50581 tacgcaatgg ctaaaggaat acgtttggga ctgctgaaca aagaagaatg gcttccacaa
    50641 gtgaagaaat cacatcaagg attacttgat gaatttgttc tggaaacaaa agaaggctgg
    50701 ctgaacttga ataaaaactg tcaagtagca gggttaggcg gagcagatca gcgagatggt
    50761 tcatatgctt actacatcag tgaaccaatt atttgtaatg atcaaaaagg cgttggtgca
    50821 ttcttgcaag cattgattga agtggaggca ttataaatat gtatgatatt ttgacatttg
    50881 gcgcatcaat tgatgaattg aatactgaag caatacaaca agccattgat gctgcagcaa
    50941 gtgacggagg cgggaccgta gttgttccag caggtgaatt tctaacagga gctttatttt
    51001 taaaaagcaa tgtcgaactt catttaagcg caggagcggt tctgaaattc tctgacgatc
    51061 caaaagatta tcctgttgtt cattcacgtt gggaaggagt ccatcgaaaa gtttatgctt
    51121 cctgtatcta tgctcaaaat gtagagaaca tctctgtcac tggtttcggt acattagatg
    51181 gaaatggaaa aaaatggtgg catactttta gaaatgaacc agataatctc gcttatcctc
    51241 gtcctaaatt gatgagtttc cataactgtc atcgaattac tgtgaaagat attaaattga
    51301 tccagtcacc aagttggacg atcaacccga ttctttgcag taatgcaacg tttgataact
    51361 tgacgatctt gaacccagcg gattcaccaa atacagacgg aattgatcca gaatcatgca
    51421 aaaatgtgcg tattagtaat tgccatattg acgtgggaga tgactgtatt gcaatcaagg
    51481 cagggactga agatacgtac gaaaggatcg cttgcgaaaa tatcacgatc acaaattgca
    51541 cgatggtcca tggacatggc ggtgtcgtat taggaagtga aatgagtggt agtattcgta
    51601 atattaccat ttcaaattgt atcttccaag aaactgatcg aggaatacga ttgaaatcta
    51661 gacgaggtcg aggcgggatc gttgaagata ttcgagtatc caatatagtc atggataatg
    51721 tgatgtgtcc atttatactg aatctttatt atttctgtgg tccgcgaggg aaagaaccgt
    51781 atgtatggga aaaaaaggct tatccgatag atgaacggac accagcattc agaaggatcc
    51841 atttttcgaa tatcacggca aggaatgtcc atgcttctgc aggttttatt tatggattag
    51901 cggaacaatt catacaagaa atcacatttg acaatatcga tgtctcgatg gcccaagatg
    51961 cagttcccgg tgttcctgct atgatgacag gaatagagga aatgagcaga caaggatttt
    52021 atattggctt tgcgggtaag gtttccttta accagatgtc gattgaaaat cacgagggac
    52081 cagcatttct attagaaaat actaaagaaa tcagtattga gaaattccaa tcaaatcaat
    52141 cagaaaatat ggatgaactg gttgttcgta aaaactttgc ttatgcagtt gaatgatttt
    52201 ttaggtgctc catctagcag acatacccct agtggaaaac gattataccg agaaaaacaa
    52261 aacggtttta tgcttgaata ctatcaattg tacttaaatg aattggaaac agtaccagcc
    52321 ctctatgctt atccagaaaa agaaggaccg tttccgccgg tcctttacct gcattctcac
    52381 ggcggagatt tttcagtcgg gaaaagtgaa ttgatccatg gtgctcctta cttagcttct
    52441 ccatcttttg cagaagtact gacaggaatg ggatatgctg tttggtcgat tgatgcttgg
    52501 ggatttgaag aacgcggagg tatttctgaa agcgagttgt tcaaacaatt tttattaaca
    52561 ggaaaaacgt tatggggaat gcgtatttat gatgtgatca gcttgatcga ttatttggag
    52621 acaagggaag acacagatac tcaacggctc gcaacgattg gtctttctat gggaggctta
    52681 ttaagctggt gggtgacagc attggattct cgtgtcaaag tttgtattga tctagcggca
    52741 caggtggaca tcgaaatact tttgctacat cgccgcctag atcatcatgg gttttattac
    52801 tatgtgccaa atctattgac agcttataca acgttagcaa tccaagaaaa aatcgctccg
    52861 cgccctcgtc ttagcttagt tggaaaaaac gatacgatgt gcttggacga aggcgtactg
    52921 aagctgagaa aagggctgga caaaaagtat caatcaatgg gtagtccaga aaacttttct
    52981 tctttttctt taacaggcgg tcatatggaa acacaagaaa tgagaaatat ttggaaacaa
    53041 ttcataaggg agcatttatg aggatgaaag acaaactgat aattggaaag aatgctatag
    53101 ataccccgac ggattttgaa actatccaag aaggaatcga ttatttggca ggcctgccgg
    53161 atagccatcc aaaggtcttg atagtaaaag aaggaagata tgatgaatat atagaaagca
    53221 gattatccaa ttttaaactt gtgggagcag gaacagtagt tatctccggt aatcgttttg
    53281 caaaacagga gtatcttgac ggtagccagt tagggacttt ccgaagtgct acttttttct
    53341 tagaaggatc gaatgtcgta ttagaaaatc ttcacatcga aaatacagca ggtccaggag
    53401 aaaaggtagg acaggctgtt gctttattca attcaggaga tcgcgtatct ttaaaaaact
    53461 gtcgactatc tggttatcag gataccttat gcacgggtcc gttgcctgat ttgcaaaaag
    53521 atggtactcc tttttgtaca ccggcttctg ccaatcctga gtattgtcgt cagacctatg
    53581 aatattgctg gattgaagga acggtggatt tcatatttgg tggggcagat gccgtttttc
    53641 atcagtgtca tatccatagc ttagccagta aaaatcctgg atacatcaca gcagcatcta
    53701 cgccgaaaaa tcaaaaaaca gggtatcgtt ttgaaagctg taccttgact gcagaacctg
    53761 atactagaaa cgtctattta ggaagaccgt ggcgtccgta tgcaaatgtc ttatttgaag
    53821 cgtgtaagat aggtgggcat gttcacccaa ctggttggga taattgggat gacaagaaaa
    53881 atgaacagac tgtcaaattc tctgaacgta ataacaatta tgaaacatcg atcaaaagac
    53941 ctgaatggat acatttagaa aagcaggggg ttcagaaatg aaaagaaaat gggaactatt
    54001 gctaggaatg gtcggtggca gtctatcttt gattttcttt ggcgggttag cagttacttt
    54061 aagtaatatg tctgcgtcag agtttaaaaa aagttatcag tcgcttgctg tagatcattc
    54121 aactttgtct ttagaaaata catttggatt attacaggac atgactggtc tgtttgccgt
    54181 tgtgttgttt atttcacttg cttttttagc agtagcattg tttttgactg ctaaaggaaa
    54241 atacttaaca actgccactg gtttgtattt tataacagga ttcatattgt tgattggcac
    54301 tcagtttatt gcgtttcctt ttgcattttt ttatttcgca gctggggcat tcagtttata
    54361 tcgagtaaga atgagaaaag gagcctgaat catgcagact atcaaagtga aaaatcctat
    54421 tttaagagga ttcaatccag atcctaatat attaagagtg aaagagcggt attacattat
    54481 tgtctcctct tttgaatggc ttccaggaat ccgagtatat gagtcgaaaa atttagtcaa
    54541 ctggtcacat acaacggata ttttgaccac tcaagtatct ttgcaaggaa atcctacaaa
    54601 tggaagtata tgggcgccac aaatcagtta tgctgatgga ttgttttatc ttgtttacac
    54661 agatgtcaaa agtgcaggcc gtccgtttaa agatgtccac aattatttga tcactgcatc
    54721 tgagatcaca ggtccttggt ccgaaccaat ttatttaaat agtaacggct ttgatccttc
    54781 tttgttccat gatcttgaaa cgggaaaaaa atggcttgtc aatgaactat gggattatcg
    54841 tctggacaca ccgaataaat ccagcggtat cgtattacaa gaatatgatg cagagaagaa
    54901 gaagcttgat ggtcccatct ataaaatatt tgcaggtaca gaattagcga aaacggaggc
    54961 accacatttg tattttcgta acgggtatta ttatttgatg acggcagaag gcggtacagg
    55021 aagaggacat tcagttacag tttgccgagc aaagaatatt actggtcctt acgagcttga
    55081 tcctggtttt cctatgctga cagctagtga caaacctgct tctacattgc aatgtacagg
    55141 acatgggagc ttagtacaaa ccccgtcagg aagatggtac atgacatatc tttgtaccag
    55201 accattaaac ggtgcggcta ttttgggaag agaaaccgct attcaagaag tgtattggac
    55261 gtccgacgat tggttaagac ttaaagatag ccagacaact ccgatggaag aaataatgat
    55321 tgagacaaat gaagaggtac aacaagaaaa agatcatcag tttatggata catttgaagg
    55381 agagctaaag aagaactgga atgccagacg cattttgcca aatgctgatt ggtgtgatac
    55441 aaaatgtaga ccaggttttt tacgtctgat ttccggtgaa tctcttcaat ctaccttcga
    55501 acatcatttg ttagctattc ggcaaacgga ttttactttt gatgcggaga cagcatttga
    55561 atacatgcct aataatttta atcagatggc tggactggta ctgtacttaa atgaatccaa
    55621 ttatatttat tgttatgtta cttggaatga ggacaaggga aaatgcctac gtatgataga
    55681 atcagaaaac ggagtagcac aaatagaaga ttggacgatt ccactcacag aaaagaagac
    55741 ttttttgaaa gtcactgtaa agaaagagac agcacagttt catttgaaag acgtatcaac
    55801 tgaagaatgg aagaaagtag gtccgcaaaa aaacatgtgt atactctcag gagggtttac
    55861 tggaaatttt atcgggatag cagtgcatga tctaaataaa aaaagaggaa gttatgctga
    55921 ttttgagttt ttcaagtatg atggaaaaga tcatctgtaa tttaattctt taataaatga
    55981 ggttcactaa cttattttca c
//
LOCUS       DACCVH010000008        53039 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.008, whole genome shotgun sequence.
ACCESSION   DACCVH010000008 DACCVH010000000
VERSION     DACCVH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.008"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(94..1137)
                     /locus_tag="IVV98_000567"
     CDS             complement(94..1137)
                     /locus_tag="IVV98_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP7806248.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1514..2479)
                     /locus_tag="IVV98_000568"
     CDS             complement(1514..2479)
                     /locus_tag="IVV98_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP7806249.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2713..3558
                     /locus_tag="IVV98_000569"
     CDS             2713..3558
                     /locus_tag="IVV98_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7806250.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3749..4936
                     /locus_tag="IVV98_000570"
     CDS             3749..4936
                     /locus_tag="IVV98_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP7806251.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4942..5298
                     /locus_tag="IVV98_000571"
     CDS             4942..5298
                     /locus_tag="IVV98_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP7806252.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5300..5638
                     /locus_tag="IVV98_000572"
     CDS             5300..5638
                     /locus_tag="IVV98_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP7806253.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            6033..7067
                     /locus_tag="IVV98_000573"
     CDS             6033..7067
                     /locus_tag="IVV98_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806254.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7060..7746
                     /locus_tag="IVV98_000574"
     CDS             7060..7746
                     /locus_tag="IVV98_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806255.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7770..8618
                     /locus_tag="IVV98_000575"
     CDS             7770..8618
                     /locus_tag="IVV98_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7806256.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8815..9588
                     /gene="sufC"
                     /locus_tag="IVV98_000576"
     CDS             8815..9588
                     /gene="sufC"
                     /locus_tag="IVV98_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP7806257.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9601..10887
                     /gene="sufD"
                     /locus_tag="IVV98_000577"
     CDS             9601..10887
                     /gene="sufD"
                     /locus_tag="IVV98_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP7806258.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10884..12119
                     /locus_tag="IVV98_000578"
     CDS             10884..12119
                     /locus_tag="IVV98_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7806259.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12106..12576
                     /locus_tag="IVV98_000579"
     CDS             12106..12576
                     /locus_tag="IVV98_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP7806260.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12581..13972
                     /gene="sufB"
                     /locus_tag="IVV98_000580"
     CDS             12581..13972
                     /gene="sufB"
                     /locus_tag="IVV98_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP7806261.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14070..15212)
                     /locus_tag="IVV98_000581"
     CDS             complement(14070..15212)
                     /locus_tag="IVV98_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7806262.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(15263..16060)
                     /locus_tag="IVV98_000582"
     CDS             complement(15263..16060)
                     /locus_tag="IVV98_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806263.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            16262..16561
                     /locus_tag="IVV98_000583"
     CDS             16262..16561
                     /locus_tag="IVV98_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806264.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            16826..17701
                     /locus_tag="IVV98_000584"
     CDS             16826..17701
                     /locus_tag="IVV98_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806265.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            17698..17916
                     /locus_tag="IVV98_000585"
     CDS             17698..17916
                     /locus_tag="IVV98_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806266.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            17903..20530
                     /locus_tag="IVV98_000586"
     CDS             17903..20530
                     /locus_tag="IVV98_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806267.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            20545..20763
                     /locus_tag="IVV98_000587"
     CDS             20545..20763
                     /locus_tag="IVV98_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806268.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            21945..22263
                     /locus_tag="IVV98_000588"
                     /pseudo
     CDS             21945..22263
                     /locus_tag="IVV98_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348881.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22282..22596
                     /locus_tag="IVV98_000589"
     CDS             22282..22596
                     /locus_tag="IVV98_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806269.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(22649..23422)
                     /locus_tag="IVV98_000590"
     CDS             complement(22649..23422)
                     /locus_tag="IVV98_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806270.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            23527..23772
                     /locus_tag="IVV98_000591"
     CDS             23527..23772
                     /locus_tag="IVV98_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806271.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            23928..24779
                     /locus_tag="IVV98_000592"
     CDS             23928..24779
                     /locus_tag="IVV98_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806272.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            24812..25486
                     /locus_tag="IVV98_000593"
                     /pseudo
     CDS             24812..25486
                     /locus_tag="IVV98_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25743..26942
                     /locus_tag="IVV98_000594"
     CDS             25743..26942
                     /locus_tag="IVV98_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806273.1"
                     /translation="MLFTSGPDRAFERLMQEKPGFDHYDGGGADAPEDCGTCRFYRPD
                     WKYQFCQFAECPYQPGKLTDYAAVKFTVKGANNAMAVFRVEKNKGYTVMSNHHLRNKN
                     LTLKAKGLLSQMLSLPEDWDYTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDA
                     KGKMADMVYTIYEQPVLENPVLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLS
                     KKEKIITDGQSTHSIPIPSPTPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEY
                     AYLIQDRSIDREQLDEIVDLMLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRF
                     VLDCLRENTTKVRNIKQYLRAMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYS
                     CGEGESL"
     gene            26964..27176
                     /locus_tag="IVV98_000595"
     CDS             26964..27176
                     /locus_tag="IVV98_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP7806274.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            27251..27727
                     /locus_tag="IVV98_000596"
     CDS             27251..27727
                     /locus_tag="IVV98_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAP7806275.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            27724..29532
                     /locus_tag="IVV98_000597"
     CDS             27724..29532
                     /locus_tag="IVV98_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP7806276.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            29609..29824
                     /locus_tag="IVV98_000598"
     CDS             29609..29824
                     /locus_tag="IVV98_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein"
                     /protein_id="HAP7806277.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            29916..30779
                     /locus_tag="IVV98_000599"
     CDS             29916..30779
                     /locus_tag="IVV98_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806278.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            30810..31352
                     /locus_tag="IVV98_000600"
     CDS             30810..31352
                     /locus_tag="IVV98_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HAP7806279.1"
                     /translation="MFISTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVE
                     RLASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTR
                     GNAEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFAR
                     QKTPGWDVWGNEVECDLILT"
     gene            31366..31788
                     /locus_tag="IVV98_000601"
     CDS             31366..31788
                     /locus_tag="IVV98_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP7806280.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            31718..34117
                     /locus_tag="IVV98_000602"
     CDS             31718..34117
                     /locus_tag="IVV98_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAP7806281.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            34149..36140
                     /locus_tag="IVV98_000603"
     CDS             34149..36140
                     /locus_tag="IVV98_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP7806282.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            36163..36414
                     /locus_tag="IVV98_000604"
     CDS             36163..36414
                     /locus_tag="IVV98_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HAP7806283.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            36404..37633
                     /locus_tag="IVV98_000605"
     CDS             36404..37633
                     /locus_tag="IVV98_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HAP7806284.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            37630..39711
                     /gene="topB"
                     /locus_tag="IVV98_000606"
     CDS             37630..39711
                     /gene="topB"
                     /locus_tag="IVV98_000606"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7806285.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            39860..43780
                     /locus_tag="IVV98_000607"
     CDS             39860..43780
                     /locus_tag="IVV98_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAP7806286.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            43781..44725
                     /locus_tag="IVV98_000608"
     CDS             43781..44725
                     /locus_tag="IVV98_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806287.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            44729..44932
                     /locus_tag="IVV98_000609"
     CDS             44729..44932
                     /locus_tag="IVV98_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806288.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(45232..45468)
                     /locus_tag="IVV98_000610"
     CDS             complement(45232..45468)
                     /locus_tag="IVV98_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806289.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(45651..46022)
                     /locus_tag="IVV98_000611"
     CDS             complement(45651..46022)
                     /locus_tag="IVV98_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806290.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(46019..47347)
                     /locus_tag="IVV98_000612"
     CDS             complement(46019..47347)
                     /locus_tag="IVV98_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP7806291.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(47308..47637)
                     /locus_tag="IVV98_000613"
     CDS             complement(47308..47637)
                     /locus_tag="IVV98_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP7806292.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(47895..48265)
                     /locus_tag="IVV98_000614"
                     /pseudo
     CDS             complement(47895..48265)
                     /locus_tag="IVV98_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            48410..48595
                     /locus_tag="IVV98_000615"
     CDS             48410..48595
                     /locus_tag="IVV98_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7806293.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            49538..50197
                     /locus_tag="IVV98_000616"
     CDS             49538..50197
                     /locus_tag="IVV98_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAP7806294.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            50200..51543
                     /gene="vanS"
                     /locus_tag="IVV98_000617"
     CDS             50200..51543
                     /gene="vanS"
                     /locus_tag="IVV98_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP7806295.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRMFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(51634..52935)
                     /locus_tag="IVV98_000618"
     CDS             complement(51634..52935)
                     /locus_tag="IVV98_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7806296.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT        15711 a        11379 c        12558 g        13391 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa aaatttgaga
     1321 agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt acgacctctt
     1381 ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta caaaaacatg
     1441 aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt ttcacaacct
     1501 attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg ctatgttctt
     1561 taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt gcaaacagac
     1621 attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg ttgaagtaat
     1681 gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag gctgcatagc
     1741 ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg aaatacaata
     1801 cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca aagtttttaa
     1861 gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc ggacgtgtcg
     1921 gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat aagaacgcat
     1981 agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag ttcccggcag
     2041 ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa attgcttcaa
     2101 ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg atcacttgga
     2161 agataacagc gcacagccaa atgaatttga caattggtgc aatactttca tatgaaacaa
     2221 aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag gcgatgattg
     2281 gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca aaaatgaata
     2341 tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg tgatagtctt
     2401 taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg atcggaataa
     2461 ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt ttagtaccaa
     2521 gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag cagacagctg
     2581 attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca tttctattat
     2641 agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat aaaaagttat
     2701 ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga aacaagaaat
     2761 ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa tcaaatcaaa
     2821 cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa agagatgctt
     2881 ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga agaatgggaa
     2941 gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg gatcgttgct
     3001 tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat caaaaggttt
     3061 cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga acaagtagcg
     3121 aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg cgtacaaaga
     3181 tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa attgtggctt
     3241 gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga agagatgaat
     3301 atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt gctgaaggaa
     3361 ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc aatgactccg
     3421 ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc tgatcagctg
     3481 ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc tcacagcgag
     3541 gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat acactaaaga
     3601 taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga aagttaattt
     3661 ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata ataatcagca
     3721 gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt cgaacgataa
     3781 tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg gtctgctctc
     3841 attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag gcgtagggat
     3901 gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc atttgaattc
     3961 caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg taatgggact
     4021 cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa actggtttcg
     4081 attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca tcttgatgat
     4141 ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga aatcggactt
     4201 ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga tcatggccca
     4261 agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt tcctgatgtc
     4321 tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg ttggagcagg
     4381 aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag ttggattcaa
     4441 atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata cgtcaggaat
     4501 gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt ttggtaaagg
     4561 attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt ttaccgttat
     4621 cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt ttattttaat
     4681 ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct atatcgcaag
     4741 cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa atatcggatt
     4801 acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct cgattttagg
     4861 gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag cacctgcaag
     4921 atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg ttcaacatgc
     4981 aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt tgatatgatc
     5041 aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca agtaccaatc
     5101 cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa agatcaagta
     5161 ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat gctgatcaag
     5221 cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga aaaaatttat
     5281 gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca acctttggat
     5341 cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag aagaacttgg
     5401 agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag atgaacctct
     5461 gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa cgggtacagt
     5521 ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt cagatgaaat
     5581 gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg aattataaaa
     5641 tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa tcataagcaa
     5701 tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg tttgaagaga
     5761 gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta gagcagagta
     5821 agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt atacggaaag
     5881 aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa tcaaggtggt
     5941 aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag gcttttttgt
     6001 ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta acgaatgtca
     6061 aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt tcactaaacg
     6121 ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa agtacattag
     6181 tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta aacgatcaag
     6241 atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc ggtatgatct
     6301 tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag ctgccgctgg
     6361 aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg ttgcgtttag
     6421 tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga cagaaacaac
     6481 gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt gatgaggcta
     6541 ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta gcgatcaata
     6601 agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc cgcaaaatct
     6661 gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac gtattgactg
     6721 tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac atcgaaccag
     6781 aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc ggccgtttgg
     6841 caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa gcgattcgac
     6901 gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa gaaggttcct
     6961 ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa gcagaagtgt
     7021 tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag cttttcagaa
     7081 acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat ccttgataca
     7141 ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt tttgggattg
     7201 atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta tggaatcgta
     7261 tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt tttgatcatt
     7321 ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat tccagctctt
     7381 gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg tgaagtcagc
     7441 cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat catctggaag
     7501 gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac aacgatctcg
     7561 atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg aggtcttgct
     7621 tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac tttaattatt
     7681 ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa aacagacaaa
     7741 agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga tttgcagcag
     7801 cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc aaagattcag
     7861 caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg cacgcagaga
     7921 ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa atcgtcaaat
     7981 tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat gccaattact
     8041 tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac tttgtcaatg
     8101 ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa gatgtttccg
     8161 aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg ggacgcatca
     8221 tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat ctggaaacag
     8281 caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat acgatcgacc
     8341 catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca atcaacgcaa
     8401 acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt gaaaaggaca
     8461 actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt gacaaaatca
     8521 aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca gacaaatggg
     8581 gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa aaaagatgag
     8641 aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat ttagaaatca
     8701 aaattgttta ataataaata aaagatattt gattttagta aggaaggtca ttgcgcttca
     8761 ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata atgcatgtct
     8821 gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct taaaggcgta
     8881 aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg cacaggaaaa
     8941 tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga aggcgaaatt
     9001 ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg acttggctta
     9061 tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga attcatgcgt
     9121 gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc atttttgaaa
     9181 aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga acgttatctg
     9241 aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt gttgatgtta
     9301 gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga tgctttgaaa
     9361 gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt gatcatcacc
     9421 cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat gatggaaggc
     9481 cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga aggctacgct
     9541 ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg gggagcaaga
     9601 atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc tttaagtaaa
     9661 ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc agatgaactg
     9721 ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga tgtgaaagaa
     9781 acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa agacaatcct
     9841 gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga attagcagaa
     9901 aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga actagtccaa
     9961 gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc actccatgta
    10021 gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat cgatgaacca
    10081 ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa gcatgtgttg
    10141 atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac aaccaaagaa
    10201 caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc tggttcaaaa
    10261 atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat gaatcgccgt
    10321 gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa tgacggtcat
    10381 gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga agtcaaaatc
    10441 gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac caataaagcc
    10501 cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg aacattgacc
    10561 tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca acaagaaagt
    10621 cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct tttgatcgat
    10681 gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc agaagaaatg
    10741 tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt gattcgagga
    10801 ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga attagtcgaa
    10861 gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat gattttccta
    10921 tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca gcgacgaccc
    10981 aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat aacgccaatg
    11041 ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa caagcaagag
    11101 aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt actcgtggta
    11161 cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc aaagcaggag
    11221 acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg cagcagttgg
    11281 caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc ttcctggata
    11341 tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt gctcatgtat
    11401 ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc catgaaaacg
    11461 gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt gatgtccaag
    11521 cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca acaggtattg
    11581 gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa tttggtggcg
    11641 aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct tggaaattcg
    11701 aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc gattatttgc
    11761 aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct tatgtgttgc
    11821 caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg aattttcgga
    11881 caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg acagctttag
    11941 acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta ttgaagtacc
    12001 ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg caagacgccg
    12061 accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg actatctaaa
    12121 ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca tcatcgtgga
    12181 agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg agatgtgatc
    12241 gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga cggcagtggc
    12301 tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg aaaatcaata
    12361 gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa agaagtcaaa
    12421 gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt tcccgctcgg
    12481 atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa cgatggtacc
    12541 gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac cagaattaga
    12601 agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag gagaaggctt
    12661 gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat ggatgcttga
    12721 attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat ggggccccga
    12781 cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg acaaacccgc
    12841 tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga ttggtatacc
    12901 agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag aagtcgtgta
    12961 ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca ctgactctgc
    13021 tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac cgccaaccga
    13081 caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta tttacgtgcc
    13141 aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg cggaaaacac
    13201 ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc actatgtcga
    13261 aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg tagaaatctt
    13321 tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag acaatgtgta
    13381 caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat ggatcgacgg
    13441 aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg gaaaaggtgc
    13501 acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag atacgggtgc
    13561 aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat caatttcaaa
    13621 agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca gtgcgggttc
    13681 gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat ccgatacgat
    13741 cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca aagtctcaaa
    13801 aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat ctgaagcaac
    13861 tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa tggaatatgc
    13921 agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt aataactatt
    13981 tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg tattttaatg
    14041 gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc aaatcggtca
    14101 ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt agttttaata
    14161 tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc aaacaataag
    14221 ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg tgtctttttg
    14281 taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt tgtgtttgta
    14341 gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat tattttcatt
    14401 tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg aatcgttctt
    14461 gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc ttgagcgata
    14521 gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg aagcgccaat
    14581 gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta cagtttaact
    14641 gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt gtaaaacttc
    14701 aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg attatcctta
    14761 cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct caagaaacca
    14821 tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct aacacttatt
    14881 ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa acgttgagca
    14941 acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa ttcatacaac
    15001 tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc tacaagtagt
    15061 ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt tgtacgtata
    15121 tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata tttttcgcca
    15181 ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt cattattgca
    15241 ggtagagaag ttatttgaag aatcaattat ttttaaattt atcgtgatta tcagttaaaa
    15301 attttgcgat tatactattt ttctcatatg ggaaattgta ttttttacta agatctgaaa
    15361 taaatttttc tgtttcaaat tggtttttag taattttata aaagaaatcc tcgacagatg
    15421 aatactttga aatatcttta taggctaagt ccatttcgtc taatagctgt tttaaagaat
    15481 caatcattct ttctttttca ccgtatttga aatcaccatt tcttatcttg tcttgaagtt
    15541 tactgttggc tcttttgaaa aatagctctt tagagataga gtgtctttgg ttagcgtact
    15601 cttcaatcag aggattgata ttattagcaa gtatctcatt tagataaatt tcaaaatctt
    15661 ttgagtaata ttttgtaaat atatttttta ttataggatt caataactca tagtctttat
    15721 ctagcgaaaa cgtatcacta tatctttctt gaatgtcttt aaagactttg tgaggtattt
    15781 ctgggaagtc cttaatatat agctcatacc ctatatcgat aaggtatgaa gttatatatt
    15841 cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt gataataatt
    15901 tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg gtcgcacgtg
    15961 gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa aggcgtaatt
    16021 gtttgattcg ttttcctgct tctgaaggat ttggcttcat cttttttctc ctttttattt
    16081 ttaaagatag tatatcatat ttataaaata aaagtattta aaagtattta ctttttatct
    16141 ggagtatgat actttattct tataaataca aataaataca tttttttacg caatttgtat
    16201 ttatttgtac ttataaaggt agaggagtta tagaataatt aattaaaaag gagaggtttt
    16261 tgtggaagca ataaaattaa tgatttcaga agaacaggag gaaatgtttc taaagcagtt
    16321 ttatcaaatt gctacaaaag ctattgaaaa ggctcaagaa aatgcgggga tgacaaggga
    16381 atatctcaat caaaaagaaa tggcggaata cttaaatgtg agtgaaaact ttttaaaaaa
    16441 tgctgtgaga aatgagggat tgcccgtagt tgaattaggg gcaagaaaat tttattcgaa
    16501 aaaggcagtt aatgagttta tgtttgctcg aatgaaaaga ggggaaaata ttggaagatg
    16561 atgaagtaga aattataaaa aaatgcttta aaaaaagaaa aaaagtgttc ccaaaagttt
    16621 gcagactggg ggaacactca ataataaagt gctgagaaaa ctttatttat agctattata
    16681 tcaaaaaaga aggtgaaaag gtgttttctt ctggaaatgt tgtagttgac aaacttagag
    16741 aaataaattt tgacggaaat gtaatccaca cacatggtac gatcaattaa gaaaaaaaac
    16801 gaaaaaaggt gttgagaagc cctatttgaa tgcaatagtt atcttagcag aaattaccta
    16861 ttggtataga cctaaaaaaa tttttaacga tgatggtcag ctacttggtt atcaaaaaaa
    16921 gtttcttgaa gatattttgc aaaaatcata taagcaatta agcaaaaaaa caggattatc
    16981 agaacgagct ataaaagatg caattgtgta cttagagaaa aaggggatta tcaaaagggt
    17041 ttttagaaat atttattatg agaaaagagc agttacatta tcaaatgtta tgtacattgt
    17101 tttaaatgta cataaattga tagaaattac ttttcctact ttggattgcg aaaaaaagga
    17161 gtatatgccg aaaattcgtc agaggggtat cgaaaaaaag agatatgtct ctttaaaaaa
    17221 aggtagaggt atgtacaaat ttgtatatac gtatacaaag actacttcac agaacatatc
    17281 aaagactact ctcgttatgg aagaagagga tattaatata aagaggattt acagtaagat
    17341 tagtgttctt tatgacgcaa ataacgaaga tggtcgaaaa ttatttcaag tgtatcacta
    17401 tttgagaaac gctaatgtag atacagaaga tatcagaaaa atcattgaat atttatctga
    17461 aaatactcag tatcttattg ctgagtgtat tataaaacaa catgaagcat gcttttttca
    17521 aagaaaaact gaagaagggt tatacgatta tgtaacatat tttttgaatg gacttcagaa
    17581 aagatataaa agtcaatttt tagaaaatgt agagcctata gatcagttca aaaaagcttt
    17641 cgaaatcaaa gagttacctg aaattactat gcataattgg ttgaaaggag aagaatcatg
    17701 attaaaaatc gcttaataga tcaaatgtgg tgtcttgatc aaaatacaga tactctcgaa
    17761 ttaatcgaga gtatctgctt caacacagta gttctcgatt taagagctga aaatgacaat
    17821 tgtgtaactc atatcataat taatcaaaaa atggctcagc agctctctga gagcctaaga
    17881 aaatgggctg aaggagaaaa ctatgaaagc aattaaagaa aaaatcgtta gtagaaaaat
    17941 aaactggtta gcactcagtg tacttgtttt aatgattagc gttgttttta caagtaatat
    18001 tgttgaagct agcattttca attggtttga tgacacaaaa agtcaaacag agtttttgaa
    18061 taattctctt tatagacctt acctaaaaaa atacaatgga gatttcctta gtcagttcgg
    18121 gatttggctt ggatgggctg tggtaaaagg catgtttact gtgactgatt cgattcaaaa
    18181 tatgattcca gatgtgttgg atttgttcaa tttcattgaa agtacagggc taaataatgt
    18241 ttatcaatca gtcataaata caattgtcgt tggattaatg atcctttcat tgatgtttgt
    18301 tggctacaag atgattactg gaaaaggaac aatagattta agatctgttg gaatgaatat
    18361 agtgatgtct gtagcgttaa ttcttttaat gccaacaatg atttctagcg gtattcaatt
    18421 tgccaaaata ttttacaatg atgctactac gattacaaat tcagatgacg gagtcgcttg
    18481 gtcattgata aaacaaggag taacagatct ggcatatatt aataaaacag atcaatactc
    18541 aagcattgat aaaacggagg atcgaaataa gttaacacga aaaaattttc aacagacaga
    18601 tttaacacaa gtgttgacgg ataaagtgat tgataaattg gaaaaagaaa atccagctgc
    18661 ggataatctt cgctatgaat tagttgaaaa ttctaataat gaatttgttg ccacaaagtt
    18721 ttctgataac ttcttatcaa cattttctga tagcttgaaa tcaggttatt atcgatatca
    18781 agcaaatctt tgggggattt cgattgggtt gacagcgttg gcaatcgcct atgtgttcag
    18841 cgcgtttgtg atcattacag caatattaga acttgcattt aaacgtgtgt taggtgttct
    18901 tgtttttgcg acagatattg aaacaggaca acgttcaaaa gttgttttat ccgatatttt
    18961 acaatgttac ttaacagttg gatttcaagg gtttggacta tctatgtttg ctatgtttat
    19021 caatttttta aatgctggac aaggtatctc cacaaatatt tttataaaaa caattgctta
    19081 tatctgtgct gtgtttgtgc tgataaaagg cagtggaaca gtcatgagat actttggtgt
    19141 tgatattgga ctcaaagaag gctatgggca acttgcttct gcttttggta tgggcgcaat
    19201 gctgtttaga aaaggatcaa ctggatttaa tcgtgctaaa ggaagcggaa atggaaatgg
    19261 atcagacagt ggagaaggag aagatcgaaa accagaaaag aatttcggcg aaactctatc
    19321 aaaaaaagct ggcaaaactg gaagagcttt gggatatgcc catgaacgtg gattatcagg
    19381 tttagcttca gatggagcta caatggctag tgaaagagca ataaaaccat ttaagagtat
    19441 gcgtgatatg gctaatgata ccaagaataa gttcaaagaa ggtttagatg atggtacagt
    19501 gtccgctatt aataaaaata gcaaacctat gttagctaaa aataaagaag atgaaactgg
    19561 aaaatatgct gattccatgc caacacgtct ttcggataga aaagatggtg ctaaggttga
    19621 aaatgccgat agaattatgt ctagttctga acgtatgcgt gaagcaatga aaaataatgc
    19681 tgaatcgaat aataatcctg taagtgcaat tcagcaaaaa gttcaacaag atattgaaga
    19741 acgtaaaaat gctatgcacg gtcaagctaa gtctgctgaa gaattaatta atcagaagcg
    19801 acaagaagct aaatacacgc ctgaagcaat gaatcgtgag gaaatgttaa ggaaacgtgt
    19861 agaagggcgt acaggagcta atacggacga aaaagaagcg ttgaccaaag aaagaatcca
    19921 agaagctaaa aactcaaata ccggattaga aaaattggtc aaagaaaatc tacaaaattc
    19981 tacaagtagt caaggtggcc gatcagtaga tgtccgagaa aatattcaag gttcattgaa
    20041 tggtcatgtc ggacggaatg ttgatgtaag agagaattta caaagctctt caaatggtca
    20101 aggtactaag acaattgatg ttcgagaaaa tgtacaaaat tctacaagta gtcaagggtt
    20161 taaatcaatg gatgtaagag agaatgtaca aaattctaca agtagtcaag ggtttaaatc
    20221 aatggatgta agagagaatg tacaaagttc tacaagtagt caaggattca aaacagtaga
    20281 tgttcgggag aacgttcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa
    20341 tatcgttgaa gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat
    20401 tgatagtgaa atccgtgaaa atgataaggg atcaaaacca agacgaagat ttacctatga
    20461 agacaacgag ttattcagag atacacttaa tgatcctaat ccgcttttcg ataatctatt
    20521 aaaaaaataa aagggggaat tgtcatgaaa ttaattctaa agattagtac gcatgatttc
    20581 ttagaacttg acgaattatg tgaatcagta aagaacgcaa caaatgaaaa aatcacggtc
    20641 actaattata ttgaactgat gattcaagaa gaattaaaga tgaaacatga gataaaaaac
    20701 aacttgaaat attgttatct agaaaaaagt gaagagataa tccatgaatt aaatggcttt
    20761 taaaaattgt atttgacatg aatttacgac aaggaattag tggggattaa gcgattattc
    20821 tcttccactt tagagaaata atgggttaaa aagccagaat acgtagagca atattgacaa
    20881 cctataaagg agctattgtt gaaaattgaa gtaacaaaaa gataaagaga ggtttacatc
    20941 tatcagatta aaagtgatag tacacccatg aaacctgcaa aagagttgaa cctaatgtat
    21001 atcggtttaa ctctttttat ttgcaaatta aaaaaatatc accgaagtga cgaatgaaac
    21061 tatgaccaaa ttaagcaaga aaatatatct tgcaaataaa gtagtataaa aagatattga
    21121 taaagccaat caaaactttg aatttcaaac gttagataat caaacagata caaaaaatga
    21181 aatcagttct acgcgtacga ttattaaaaa taataaattt tcactagaag aaaatggaaa
    21241 taaaatcaaa taattaggaa gaaaaaacaa agcaattaga aaagcctgca agcaaatttg
    21301 agtaatcgag atccaatttt tttaaggaag tttaacaaaa atatgtaatt ctattatcac
    21361 tattaaagag aaagttggag cggaatataa agaaaagaga aaagtaatta aacgcaaaaa
    21421 aatgtagaac ttaaaaaata taaagaggaa caaccgttaa aattaggaat gatgttgtgt
    21481 aaacattata attgctatga tataaatgaa gtgttaaaga aagcaaattt aaaccaattt
    21541 tgtgaacaga aaagccttag tcactatgac caaaactacg gacgaaacta tgaccaaaag
    21601 taggtactaa attatgaccg aaaataggtc caaaatggat ttttttatga tatcaaaaat
    21661 tatgaaatga ttttgaaaga aaaccagttg gcacagccaa cttagccacc ttcctgtagg
    21721 aaggtgctat cagttttccc ttatgctctt ttctttcttt tttgtttcat atgtcaaatg
    21781 ccattttgaa atgtaccatc ttaagaaatt tatccttaaa aacaattgcg ttattggata
    21841 aaaagatgct acattatctt aaaaaaggaa tcaaatatga tgaatttagt ggctagcata
    21901 tcgtgtgatt aagatacttt atagtgtaag ttgaaggaga aaaaatattt aaaatatact
    21961 tcccatttca gtgggaagta aaattaatct tgttgtttct actagtaatg tatctttttg
    22021 gaaactatgt aacgatgtaa acaagatttt tttcagaaga aaaaacgata aaagttgtga
    22081 taaacgattt aaaaaatagg agaaaatata tcaagcgcat ggtatgaaac gcacatttaa
    22141 aaagattcga ctaactaaaa aaataagttt acaaagcatt gttgtgtatt acaagtgatc
    22201 tatacactga aaaatgatag agaaaatctg atacgtccgc aacaatggac aattgaaaat
    22261 gaaagtgagg aaattggaag aatggctgat gaaaataaag ttgttccgct tgaaacacta
    22321 gtgataaata aggaagagtt tgagcaactt tttcttgatt tttttgttca atatgacagg
    22381 atttatgatt ttagttcgtc actagattta tttgaattag aggcagaaat aatagaaaac
    22441 agtcgagagg agaatggtaa aatcatcatt tcagtagaaa aattcaatga attattctca
    22501 gaaacatttg aaatagatac agattattat caaccacaag aagttttcca atcatttaga
    22561 aatcagatta ttcgctcagg taagaccgta aactgaaaaa caataaaaga aacgttgaaa
    22621 gaataattat tccttcaacg tttctttttt agaatgtttt aatgaccaaa gcagtttcat
    22681 tgtcaggctt aggtaattca tgaaatcccg tatttatagt gctcaattga tcaactaacc
    22741 atgttttact ttttgaattg tagataaatc taaaattaat atcgttatta tcgtgttgaa
    22801 ggggcgtctc caaataatct gctgtatatt catagtcaac gtaacctgct aatacaaaag
    22861 agagtatccc tttatttaat gttagattta atggataatc atacgacttt atttttttca
    22921 acttcatatt gtacatatct tcagccataa aagttgagtt cgtgatttca tcttgggtct
    22981 cattaaaaaa gttatccgaa taatcgctta tttttgaaaa gtctttattg gcaccagcct
    23041 caaaaaattg ttcaactttt tcagtataaa gttgtgctaa cgctcctttt tcaatattaa
    23101 ctttaatatt ttcatgtcta tcaatttgtg tgctgttcag taagggaaga tcagctttta
    23161 gttttatatc gtcttgattt ctttcaattt caattggcaa aatcttttca gtagattcag
    23221 tttctgataa aggaacatct agttttttat catgataata agcttcaaat ccatctggaa
    23281 ccggaaaaaa atgtattggg taattctttt ctgaggttgt tgtactagtt tccgtacttg
    23341 tagaacttgt gtcagaagtg gtacacccgc ttatagttcc gatgagtaaa gcgcaagtta
    23401 gaatgattgc aaatttcttc aaaaaaattc ctccttaaaa ttgaatatgg actaatacta
    23461 gtcccattgt agcataccga atctttaaga ttaataagaa aaaggactaa ttttagtcca
    23521 aaaggtgtgc tattcttgaa agaggaaaaa attattgata aagaaaatgt aatcggtagc
    23581 aatattagac gagtccgatt agaaaaagga attggtcaaa ccgagctgat tagagaccta
    23641 cagcttcgta aaattgctat aactagggaa acgttggtta agattgaagg tggccgccaa
    23701 cacattaagt tggatcaatt gaaagccatc aaagatattc tacaggtgtc ttatgaagat
    23761 ttgcttcaat gactacttgt agtcatttcg tttgaaatta ttatgttaca cccttatgtg
    23821 tcacgaagaa atactggtat aataatgaat gggatatgta acgatagggt atactgttat
    23881 gttgcctaat aaattgtgga tcaaaataca agaatggagg gatatccttg tataaggcat
    23941 atgaattgga ttttacaaat gctgacttaa atgcattctc ctcaagctcg caatcatata
    24001 cacatgtagt aaatcaaata gatcacaacc aaaaatctat taacaagaga atagaaaatc
    24061 tatttgaaag tgaaaatgat ttagttgatt attattctaa ggacagcaaa attctagatg
    24121 cagacgaaat tattaaagat tggtttccaa ctataaaagc agatattttt atatctcact
    24181 ctcatgctga tgaaaaatta gctatacgtt ttgcatcatg gctatttgaa aattttggtc
    24241 ttactgcatt tattgattct tcggtttggg gatacagttc tgatttatta aaaaaaatag
    24301 accaaaaata ttgctataag gaacaaacaa aaacatatga ttatgataaa agaaatgtaa
    24361 caactagtca tgttcatatg atgctttcta cagctttaaa taatatgatt gatagtacag
    24421 aatgtctgtt ttttcttaat acacctaatt caattagttt gagcaatgaa atcactaatg
    24481 aacagaaatt tacgtattcg ccatggctat atagcgaact gacgacagct tcaatagtgg
    24541 aaaaaaagaa tccacgattg gaaagtaatc ctcaaatgag caccgaggat gttagaagca
    24601 ttataaagca ctattcttcg caagaaaatc tgcaaataaa atattcttta aatttaagtg
    24661 aattaactta tttacgaaaa gctgatttga aaaaatgggc tttagatgct gtggaatgca
    24721 ctaaaggaag taatacatta gatattttat ataaaaacac cattttcact aatctctaat
    24781 caatttactg aatcgaaagg aaccgggtag aatggataag aaagttttaa taaagaggtt
    24841 ctctgaagct attgaaaaag gaaatgcagc aatatttgca ggtgcaggat tatcgatgtc
    24901 acaaggatat gtaagttggc cggaactact taatgatcct gcaacagaaa tcgggttgga
    24961 ttctaaaaaa gaaacagact tagttactct ggctcaatat tataaaaatg aaaatggtgg
    25021 atcaagagga attttgaatc agatacttat ggataatttt ggtgaagaat tagaaatatc
    25081 tgaaaatcat cgaatactag caagtttacc tattgaaact tattggacaa ctaattatga
    25141 tcatctaata gaaaaatcaa tccgagaagc ttataaaaac cctcaggtta agaaaaatta
    25201 tactcagtta gcaacaacta atccaaatgt ggatacaatt gtttataaaa tgcatggtga
    25261 tatagatgat gtcagttcga cagtaataac aagagatgat tatgaaaaat atgatgattc
    25321 gtacgcgtta tttaaagaaa ctttaaaagg agatttgtta acaaaaactt ttctcttttt
    25381 aggatttagt tttacagacc ctaatttaga aagaatttta tcagatataa gatgggtttt
    25441 gagagaaaac caaagacctc attattgtat aatgagaaaa atattataga aaaaatttta
    25501 ggttatcgct gaaagccccg gaaatacggg catttcgcag gatatgagaa ctcaatttac
    25561 taccaattta ctactttcgg attgagccgc atatatgctg aaccatactg ctaatacccg
    25621 ccaccccaaa tacggcacat cataaattga atacgacacc gtaaacgcgg cgttcctctt
    25681 tcccgtcatg ggagaacagg acgccgcttt tttatgccca aatagagaaa ggaggcgacg
    25741 ccatgctatt tacttccggc cctgaccggg cgtttgaacg gctgatgcag gaaaagcccg
    25801 gtttcgatca ctacgacggc ggcggggcgg acgcgccgga ggattgcggc acctgccgat
    25861 tttaccgccc ggattggaaa tatcaattct gccagtttgc agagtgtccc tatcagccgg
    25921 gcaagctgac cgactatgca gcggtcaaat tcacagtgaa aggagcgaac aacgctatgg
    25981 cagttttccg tgtggaaaag aacaaaggct atacggtgat gtcaaatcac cacctgcgga
    26041 ataagaacct gaccttaaag gccaagggcc tgctgtcgca gatgttgtcc ttgccggagg
    26101 attgggacta taccctaaaa ggactgtcct atatcaaccg ggaaagcatc gacgcgatca
    26161 ggacagcggt atgggagctt gaaaaagctg gatatatccg gcgtgagcag ggccgtgacg
    26221 caaaaggcaa aatggccgat atggtctata ccatctacga acagccggta ttggaaaacc
    26281 cggtattgga aaatccaaca tcggataacc cggtgttgga aaatccgaca tcggataatc
    26341 cggcgtcgga aaatccaacg caattaaata aagaagtaca aagaactgac ttatcaaaaa
    26401 aagaaaaaat aattacagat ggacaaagta cccattccat tcctatccca tccccgaccc
    26461 ctgcccctat ggagggcgag gcagcggcta cgccgccgga acggaaaagg acaggaaagg
    26521 atgaggctgt acggatttat cgggaaatca ttttggagaa catcgagtat gcctatctca
    26581 ttcaggacag gagcattgac cgtgaacagc ttgacgaaat cgtagacctg atgctggaaa
    26641 ccgtctgcac cgcccgaaag acaatccgtg tcgccgggga cgactaccct gccgagctgg
    26701 tgaaatccaa gtacatgaag ctgaccggcg aacatatccg ctttgtcctt gactgtctgc
    26761 gggagaacac aacgaaagtc cgcaatatca aacaatacct gcgggctatg ctgttcaacg
    26821 cccccagcac catttccaac tactacacgg cccttgtcgc gcacgacatg gcacagcccg
    26881 attggggaaa gcctaaatcc ggcctgccgg actattcctg cggcgagggc gaaagcctgt
    26941 aacgagaaaa ggaggacgac cctatgaagc agggcgcatt gatttttgac gagcgaacag
    27001 accgttacga catccgcttt gatctggccg actattacgg cggcctgcat tgcggggagt
    27061 gtttcgacgt gatgatcggc ggcaaatgga ggcccacccg cattgaaatg gccgaaaact
    27121 ggtatcttgt cggcatccgg gccgacgacc tttccggcct gcgggtgcgg atttgaccta
    27181 tatctacctg cggcgtctgg tggttccgcc ttagacgccg cttttgactt tctgacaagg
    27241 agggatgcga ttgcaggaag aagttactca aaagaccatt gccctgtcca tgaaaacggg
    27301 caagctcacg gctcaagtgc tgcaagcggc gctgaaaaag tacctgcaac accgggccaa
    27361 gggcaaaaac acgctgcacc acggccagca gagcctaaag cagcttaaaa agcatggggc
    27421 tgatctctcc aacattgaga tcaccgaggc caacattgga gcgttcaagc catgcgccaa
    27481 gaaatacggc gtggatttta ccttacgaaa agataagacc acccagccgc cccactacgt
    27541 tgtgattttc aaggccaagg atgcagataa ccttgatctg gcgtttcggg agtttaccgc
    27601 caagacgctt tccaaggagc agcggccctc tatccgcaag gttttgtccg ctgtgaagca
    27661 aaaggcggcg gcccagacca agcagcgggc caaggagaaa atcaaggaaa gggggctgga
    27721 actgtgaagc ctgacgtaaa gaaattgctg atcctgaacc tcccgtatct gatttttgtg
    27781 tacctgtttg cgaaatgcgg ggaggcgtac cggctggccg ctggtgctga cctgtcgggg
    27841 aagctcctgc attttgcgga tggttttgcg gcggcttttg ccaacccgct gccaagcctg
    27901 cacctgtttg acctgtgtat cggtatcgcc ggtgccgtga tcgtgcggct ggtggtgtac
    27961 tgcaagagca agaacgtgaa gaaataccgc aaaggcatgg agtatggcag cgcccgctgg
    28021 gggacggcca aagacatagc gccttacatc gaccccaagt ttgaaaataa tatcctgctc
    28081 acccaaacgg aacggcttac catgaccggc aggcccaaag accccaagac agcgcggaat
    28141 aaaaacgtgc tggtgatcgg tggcagcggt tcagggaaaa cgagattttt cgtgaaaccc
    28201 aacctgatgc aatgctttcc gaccacggac tatccgactt cgtttgtggt gacagatccg
    28261 aaaggcactt tggttctgga aaccggcagg atgttccagc aggcgggcta ccgcattaaa
    28321 atcctgaata ccattaactt ttccaagtcc atgaagtaca acccctttgt ctacatccat
    28381 tcggaaaagg acgtgctaaa gctggtaaat accctgattt ccaacaccaa gggcgagggg
    28441 gaaaagtcag cggaggattt ttgggtgaag tcggaacggt tgttttattc ggccctgatc
    28501 ggctatatct ggtacgaggc cccagcggag gaaatgaact tctcaacgct gctggaaatg
    28561 ataaacgcca gtgaagcccg cgaggacgac ccggagtttc aaagccccgt cgatctcatg
    28621 tttgagcgtt tggagcagaa agaccccgac cattttgcgg tgcgccagta caagaaattc
    28681 ctgctgtccg caggcaagac ccgttcttcc atcctgattt catgcggtgc cagacttgcg
    28741 ccctttgaca tccgggaggt acgcgagctg atggaggacg acgaaatgga gctggacacc
    28801 atcggggacg aaaagacggt gctgtatctc attatgagcg atacggacac gacctttaat
    28861 ttcattctgg ctatgctcca aagccagcta atcaacctgc tttgtgaccg ggctgatgat
    28921 gtgtacggcg ggcggctgcc tgtccatgta cgcctgattt tggatgaatt tgccaacatt
    28981 ggccaaatac ccaatttcga taaactcatt gccaccattc gaagccgtga aatatcggcc
    29041 tctattattt tgcagagcca gtcgcagcta aaagcgattt acaaggacgc cgccgagatc
    29101 atttcggata actgcgatag tgtgcttttc cttagtgggc gcggcaaaaa tgccaaggag
    29161 atttccgatg cgctggggaa agaaacgatt gacagtttca acaccagcga gaaccgggga
    29221 agccaaacgt cccacggatt gaactatcaa aaattaggaa aggagttgat gtcccaagac
    29281 gaaattgccg tgatggacgg cggcaagtgt atcttgcagc tacggggtgt gcgcccgttt
    29341 ttatcggaga aattcgatat taccaagcat ccccggtaca aataccttgc cgacgccgac
    29401 aagaagaata cctttgacgt ggacagattt ttgactatca cgcgccggaa acggcagcaa
    29461 gtggtaacgc aggatgaagt attcgacctg tatgaaatcg acctgtcgga cgaggacgcc
    29521 gccgctgaat aaacagcggc ttttttcatt ccaacaacaa aatcaaaaaa tcattatgag
    29581 ccggaaaccg gcagaaagag gtaaatttat ggcatttttt aattccgcag ttactacttt
    29641 gcagactatc gtgatcggac tgggcggcgc tctgtgcgta tggggcggca tcaatctgtt
    29701 ggagggatac gggcaggaca atccgggggc aaaatcgcag ggtgtcaagc agcttgtcgc
    29761 tggcggcggc gtggccctga tcggtgtcac tctggttccc ctgctgtccg ggctgctggg
    29821 ctgatcctgg cctttgtccc tgtccaaacc cttaactaat cgcctccgcg tcctcccggc
    29881 cagaccggga gggcgcggga aaggaggtgc tacccgtgat tagtgaaatc attgaagaat
    29941 ggataaaagg catcctcatg gacggtatca cgggcaacct gtccgggctg ttcgatacgg
    30001 taaatgccaa agtcggagaa atcgccgccg acgtgggacg aaccccgcag gcatggaaca
    30061 gcggtatttt caatatgctg cacagcctgt cggaaaccgt gatcgtcccc atagccgggg
    30121 ccatactcgc ccttgtcatg tgctatgagc ttatccagat gataacggaa aagaacaata
    30181 tgcacgactt tgacagctcc atgttcttcc gctggatatt caaatccgcg tttgcaatcc
    30241 tgatcgtaac gaacacatgg aacatcgtca tgggcgtatt cgacgccacc caaagcgtcg
    30301 tcaatcaaag cgccggtgtg attatcgggc agacatccat tgattttaac accctgatac
    30361 cagaccttga aagccaattg gaggctatga gcgtgggcgc tcttttgggg ctgtggttcc
    30421 aaacccttgt tgtgggcctc accatgaata tcctttccat ctgcattttc cttgtgacct
    30481 atggccgcat ggtggaaatc tatgttgtca cgtcgctggg gcctatcccc cttgccacaa
    30541 tgggcaacgc ggaatggcgc ggcatgggcc aagggtatct gaaatccctg ctggcgctgg
    30601 gcttccaagc ctttttaatc atggttgtgg tgggtatcta cgcggtgctg atacagaata
    30661 tcggttccgc ttccgacata tccggcgcaa tctggggctg tatgggctat acggtgctgc
    30721 tgtgcttctg cctgttcaag accggcagta tatcaaaggc cgtattcggg gcgcattgat
    30781 cccaaaatcc aagcatacac aggaggaact tgtttatttc aacgtacaac atcatttacg
    30841 ctgacccgcc gtggcggtat gactgcaaaa acgtacaggg cgcagcggaa aatcactatt
    30901 ccaccatgag cattgacgag ctgtgcgccc tgccggtgga acggctggcg tccaaagact
    30961 gcctgctgtt tttgtgggcc acattcccca tgctgccgga agctctgcgg ttaatcaaag
    31021 cgtggggctt ttcattcaag accgtggctt ttgtatggct gaaacagaac cgtaaaagcc
    31081 ttacatggtt ttacgggctg ggccgctgga caaggggaaa cgcggaaatc tgcctgctgg
    31141 caacacacgg caagccgaag cgtcgttctg cctctgtcca tcagtttatt atcagcccga
    31201 ttgaacaaca cagcaaaaag ccggatgtga cccgtgaaaa aatcgtagag ctggcgggcg
    31261 atttgccccg cgtggagctg tttgccagac agaaaacccc cggctgggac gtgtggggga
    31321 acgaggtgga atgtgacctt atcctgacgt gaaaggaggt gccaaatggc ttatgtaacc
    31381 gtccccaagg acttaaccca tgtgaaaagc aaggttgtgt ttgggcttac caaacggcaa
    31441 ctgatctgtt tttccggggc gctggtgatc ggcgtcccct tatattttct cacccgtgac
    31501 tatcttacca acagcgcggc ggccctgctc atggtatttg ccatgctgcc gggctttttg
    31561 cttgccatgt acgagcgtca cggccagccc cttgaagtgg tgattatgca gatcatccag
    31621 tgctgcttca tccagccaaa ggagcgtccc tatcagaccg acaacaccta caccgccctt
    31681 gtgcggcaat accagatgga acaggaggta aaggccattg tccaaaaagg aaatcccaag
    31741 agaaaccgaa aaaacaaagc tgacccgcgc ccagcgaaaa gaaattgacg cggtaatccg
    31801 taaatataag ggcgacggca ggccccacac ggcgcagcag agcatcccct acgaggtcat
    31861 gtacccggac ggcgtgtgcc gggtatcgcc cggcgtcttt tccaagtgca ttgagtttgc
    31921 ggacatcagc tatcagcttg cccagccgga cacgcagacg gctatctttg aaaaactgtg
    31981 cgacctgtat aactatgtgg acgcctccat tcatatccag ttttctttcc tcaatcggaa
    32041 agttgacccg gtgcagtacg ccaagagctt tgagatcgcg ccgcaggggg acgacttcga
    32101 cgacatccgg gccgagtaca ccggcattct gcaaaagcag cttgcaaacg gcaacaacgg
    32161 catggtaaag accaaatacc tgacattcac catcgaggcc gaaagcgtga aagcggcgcg
    32221 agccagattg aagcgcatcg gctttgacct gttaggctat ttcaagagca tgggggccgt
    32281 agcccatgtg atggacggct gggaacggct gaacctgctg catggcgtgt accacccgga
    32341 cggcgagata ttcaattttg actggaagtg gctggccccg tccggcctct ccaccaagga
    32401 ttttattgcc ccgtcctccc tgtgcttcgg caatgcaaag acattcggca tgggcggcaa
    32461 atacggcgcg gtaagtttcc tgcaaatcct gtccccggag ctgtcggacg atatgctggc
    32521 cgacttcctc aatacggaaa gcggtgtttt agtcaatctc catgtgcagg ccattgaaca
    32581 gaccaaggcg atcaagacca tcaagcgcaa aattaccgac cttgacgcta tgaagattgc
    32641 ggagcagaaa aaggccgtcc gcagcggtta cgatatggac attcttccca gcgaccttgc
    32701 cacctacggc gaggacgcca agaagctgct gacaaagttg cagacccgca atgaacggct
    32761 gttccagttg acgttccttg tcctcaacgt ggccgacacc aagcaaaagc tgaataacga
    32821 cgtgttccaa gccgcaggcg tggcccaaaa gcataactgt ccccttgtcc ggctggacta
    32881 ccagcaggaa cagggccttg caagcagcct gccgctgggc gtcaatcaga tcaagataca
    32941 gcgcagcctt acgacttcca gcgtggccgt gttcgtcccc tttgtgacgc aggagctttt
    33001 tcagggcggc gcggccatgt attacggcat caacgccaag tcccgcaaca tgattatgct
    33061 ggacaggaag caggcccgtt gccccaatgc cttgaagctc ggcacccccg gcagcggcaa
    33121 atccatgagc tgtaaatccg agatcgtcag tgtgttctta acgacgcctg acgatatttt
    33181 tatttcagac ccggaggccg aatattaccc ccttgtcaaa cggctccacg gacaggtaat
    33241 ccggctgtcg cctaccagca aggactttgt gaacccgctg gacatcaacc tgaattattc
    33301 ggaggacgat aacccgctgg ccctgaaatc cgactttgtg ctgtcgttct gtgagcttgt
    33361 catgggcggc aagaacgggc tggaagccat tgaaaagacc gtgatagacc gggctgtgcg
    33421 cgtgatctac cggccctatc tggcagaccc ccgcccggag aatatgccga tcctgtccga
    33481 cctccacaaa gcgttgttag atcagcatgt cccggaggct gaccgggtgg cgcaggccct
    33541 tgacctgtat gtgtccggct ccctgaacgt atttaaccac cgtaccaacg tggacatcgg
    33601 caaccggctt gtgtcctttg acattaagga gctgggcaag cagctcaaaa agctggggat
    33661 gctcattgtc caagaccaga tatgggggcg cgtcacggcc aaccgaagcc aaggaaaggc
    33721 cacatggtat tttgccgacg agttccattt gcttttgaaa gaggaacaga cggcggccta
    33781 ttctgcggag atttggaagc ggtttaggaa atggggcggc attccaacag gtgccaccca
    33841 gaacgtcaaa gacctgcttt cctccccgga aattgaaaat atccttgaaa acagcgactt
    33901 cattacgctg ctcaatcagg cgtccgggga tagaaaaatc cttgcggaac gcttgaattt
    33961 gtccaccgaa cagcagaagt acatcgacaa ttccgaaccc ggcgagggcc ttttgatctt
    34021 tgaaaacgtg gtgctgccct ttaccaaccc catcccgcac aacacccagc tttacaagat
    34081 tatgacgacc cgcttaaacg aggtggcggg agtatgaccc ggcgacgcca caaaggaggt
    34141 gaaccaccat gaaagagctg aaagccaagg cgaaagtgac gcaggccatg acccgcgacg
    34201 ggctgacgct ggaaaatcag gccaccggcg aggtggagaa catttccagc cgggaggccg
    34261 aacaggattt gtccgcgccg gggccgggcg gcaccgccga taagctgctg gaacgggccg
    34321 acgccatcca tgacggccat aaggccaaga aagccgcgaa gcaggccggg gctgtggccg
    34381 ccgaggggga cgctgccctg caccggccat ccgcccggct ccaactgtcg gaggaagaac
    34441 gggccgaccc ggatttacag ccctatatcc gaaaatcgga caaacgggcc gataagctgg
    34501 ataaggcccg cgccgccatc cccaagaagc gcgtcccggt caaggaaacc gtctttgacg
    34561 aggcaagcgg caaagcaaag accgtcctgc actttgacaa acaggacaag gggcctccct
    34621 ccctgaaacc caatccggca ggccgtcctg tttccgaggt ttttctattc ggccacggga
    34681 aaatccatga agtcgagcat gaaaacgtgg gtgtggaggg cggccataag ggggaggaac
    34741 ttgccgagcg gcaggccgga aaagccatcc gcagcaccat ccggcaccac aggctgaaac
    34801 cctactggga cgcggaaaag gccgagcgca ggctattgtc tgccaacgcg gagtatttct
    34861 accagaaatc tttgcgggat aacccggaga tcgcacaggc ggccagcaac cccatttccc
    34921 ggttctggca gaaacagcag atcaagcgcc agtacgccaa ggccgcccgg acagcgggcc
    34981 agaccgcagg cgcggcggca cagggcgcgg ccaagacagc cggggcctcc acgaaagcgg
    35041 ccaaggccgc agccaaagaa agtgaacggg cggcctcctt tgtggcccgc cactggaaag
    35101 gggcgctggc cgtccttgtg ttggggcttt tgatgctgct tatcatcggc ggcttacagt
    35161 cctgcaccgc catgttcggc agcgccggaa gcggcatcac ggcgtcctct tacttttccg
    35221 aggatagcga tatgttggcc gccgaggacg cctacgcgga gctggaagcc gagctgcaag
    35281 actatctgga caactacgag gccacccatg actatgacga ataccatttt gaccttgacg
    35341 agatcagcca tgacccctat gtgctgattt ccattctgtc ggcgctccat gacgggatat
    35401 ttaccatcgg ggaggtacag ggtgatttgt ccatgctctt tgacaagcaa tatatcctga
    35461 cagaaaacgt cgtggtagaa acccgttacc gcaccgaaac cgatacatgg acggacgcgg
    35521 agggcaacac ccatacagac acctaccaag tgccgtatga ctattacatc tgctacgtca
    35581 cgctggaaaa cttcgacctg tcccatgtgc cagtctatat catggacgag gaaacgctaa
    35641 gtttctattc cctgtatatg tccacgctag gaaaccggcc tgatctgttt tccggcagcc
    35701 agtaccccaa cgcctccacc ctgacgccgc cgacctacta cgacgtaccc ccggaggctt
    35761 tggaggatgc cacctttgcc gccatgctca aagaggcgga aaaatatatc ggttatccct
    35821 atgtgtgggg cggcagctct cccagcacca gctttgattg cagcggcttc atttcgtggg
    35881 taatcaatca tagtggatgg aacgtgggac ggctgggggc gcagggccta tataacatct
    35941 gcacccctgt ttccagttcg caggccaagc ccggcgacct tgtatttttc aagggaacct
    36001 acgacacccc cggcgtgtcc cacgtcggcc tgtatgtggg caacaatgtg atgctgcatt
    36061 gcgggaaccc gatttcctac acgaacctta cttcaaacta ctggcaatcc catttttaca
    36121 gttacgggcg tttaccttaa cgccagaaag gagctttcaa ttatggcaac caaacttgac
    36181 cgcatcgaaa aggacatcca gaaaaccaag tctaagatcg cggagtttca gaaacagctt
    36241 cgggagctgg aaacgcagaa aaccgaacag gagaatttgc agatcatcca gcttgtgcgc
    36301 ggcatgaaca tgaagccgga ggaatttgcc gcgttcttac gcagcggcgc aatgcaggcc
    36361 gcccctgccg caacccctta ccatgaacag gaggacaatg cccatgaaga ataagaccag
    36421 acggatttcc cgtattctcc ccgcacttct ggccgtgatg ctctgcgtca cggcctttcc
    36481 cgttaccgcc cttgcaggcg gcaatgaccc ggcaccggcc ccgctgccgg aggctacaac
    36541 cgaacccgct acgggcggtt tggagcctga aacagacgaa accggcaccg ccacggacgg
    36601 gacagaaacc gaggccgaaa aagataccgg ccctctgacc ggcaaggaca tcaccgacct
    36661 gttttccgcg ctgttcggtt ccaaggtgag cattgccgcc acggacgacg gcatccagat
    36721 caccaccggc accgacaaaa aagaacctga acagaccggc accgtcacca ccaacggcgg
    36781 caggctgaat gtccgcaccg gcgcggggct tgacaagacc gcgttcaccc agcttcccaa
    36841 tgggacgacg gttgaggtag tcggcacaga cggcgactgg attaaaattc tcttgccgga
    36901 gcgcatcggc tatgtccatt ccgactatat gaccgtcagc gaaaaggaag tagcggctac
    36961 cggcgagggc ggtttttccc tctccattga cccggaggaa attgcttctc tgctggaact
    37021 gttcaatggc ggcggggcca gcgccgccct gtccccggac gggaacctgt cactgattga
    37081 cgacatcggc agcgccgcga aaaatggcaa gcagtttatc accgtggaaa ccaaaaacgg
    37141 caatgtgttt tatctgatta ttgaccggga cgacgaggga aaagaaactg tccatttctt
    37201 aaatcaggtg gatgaagccg atctgctgac gctgatggag gacggggaaa ccgtcacccc
    37261 cgctgctgtc tgctcctgta ccacgaaatg caaggccggg gctgtgaaca cgaattgccc
    37321 ggtatgtaaa accaacctga ccgagtgcag cggcccggag ccgcaggaac cccagccgga
    37381 ggaacccgaa gccccggagg aagaacccaa gggcggcgcg ggcggcctga tcgtgttcct
    37441 gctggtggcg ctggcgggcg gcggtgcggc cctttactat ttcaagttca aaaagcccaa
    37501 ggctgaaacc accggcagcg acgatttggg cgagtatgat tttggggagg acgaggattt
    37561 ggaggacgag gaacccgaaa ccgagtttga cccggaagct gattttgtga gtgaacagga
    37621 ggacgaggaa tgacatataa acttgtaatc gcggaaaaac ccagcgtggc ccgcagcatt
    37681 gcgggcgtga tcggggccac ggagaaacac gacggctatt tggaggggaa cggctatctg
    37741 gtgagctggt gcatcggaca tctggtgtcc tttgccgacg ccggacgcta tgacgagcgt
    37801 ttcaaaaaat ggcgctatga ggatttgccc attctcccgg aaacatggca gtacatcgtc
    37861 cccgacgaca agaaacagca gtttgacgtt ctctgttcgc tgatgcagcg ccccgacgtg
    37921 accggccttg tgtgcgccac cgacgccggg cgcgaggggg aattgatttt ccgtttcgtc
    37981 taccagatgg cgggatgcca aaagcccttt gagcgccttt ggatttcctc tatggaggac
    38041 agtgctatta aggacggctt tgcccacctg aaaccgggcg gcgactatga tccgctgtat
    38101 caatcggccc tgtgccgggc caaggccgac tggctgatcg gcattaacgc cacccggctt
    38161 ttttccgtcc tgtaccacaa gaacctgact gtgggccgcg tccagacgcc gaccttaaaa
    38221 atgctggtgg acagggacgc caagattacc gatttcaaga aagagaaata tcacatcgtc
    38281 catatcacgg cgggcggcgc ggacgcggta agcagccgct tttccgacgc tgccgaggca
    38341 aacaccgtca aggcggcttg tgcaaaagcg caggccgttt gcgtttccgt gacgcgggag
    38401 aaaaagacgg aacagccgcc caagctctat gaccttacca ccttgcagcg ggaggctaac
    38461 cggcttttcg gctataccgc caagcagacc cttgactatg cccaggcact gtatctaaag
    38521 aagctgctga cctatccgag aacggatagt caatatctta ccgacgatat gctgcccgcc
    38581 gtggaaagcc ttgtgtccgg cctgtgggag ctggtgccgt ttgccaaggg cctgaacctt
    38641 tccccgcagt ttgaccgcat cctgaacagc aaaaaggtgt ccgaccacca cgccattatc
    38701 cccaccgctg aatttgtgaa gcagggcttt ggcactctgg ccgagagtga aaaaaagctg
    38761 ctgtccctga tctgctgcaa gctcttatgt gccgtggccg ggccgcatat ctatgaggcc
    38821 gtcaccgcca catttacctg tgccgggcag gagtttaccg ccaagggcaa gaccgtcctt
    38881 tcccccggct ggaaagagat tgaacgccgg ttccgttctt ccttaaagac cgacgccgac
    38941 gaggacgccg aggcggtgcg ggagctgccg gagctttgcg agggccagac ctttgcagac
    39001 gtggccgcct ctgtcaccga gcatttcacc acgccgccca agccctacac cgaagatacg
    39061 cttttgtccg ctatggaacg ggccggggcc gaggatatgc cggaggatgc cgagcgcaag
    39121 ggattaggca caccggccac ccgcgccgcc attctggaaa agctggtgca gatgggcttt
    39181 gtccagagaa aaggcaagca gctcattccc accaaggacg gcatcaatct ggctgtggtg
    39241 ctgccggagg cgcttacttc tccccagctt actgccgaat gggaaaaccg gctgaccgag
    39301 atcgccaagg ggcaggccga tcctgacgaa tttatggacg gcatcgagac gcaggcgcgg
    39361 gagctggtgc agacctattc ctgtatcagt gaggaaaagc agaaattgtt tcaggccgag
    39421 cgtgttccta tcgggacgtg tccccgctgt ggtgaggctg tctatgaggg caagaaaaac
    39481 tactactgcg gaaaccgggc ctgccagttc gtcatgtgga agaatgaccg attttttgag
    39541 gaacgcaaga aagcgttcac cccgaagatc gccgctgcgc tgctcaaaac cggcaaagtc
    39601 aaggtaaagg gcctctattc cgtaaagacc ggcaaaacct acgacgggac ggtgcttttg
    39661 gctgataccg ggggcaagta cgtcaactac cgcattgaac acaggagcta aaggacagta
    39721 acacagcaag catagggagt gtggctacac tcccggtaaa atcccccggc cgcgtccctg
    39781 ccgggccggg gatttttgct tgttggggaa gtccccaacc ccctattttt tgaaacagaa
    39841 cagagaaagg agtgaccgcg tgaacgaagt attttctatc caagtccata accggcagtt
    39901 tttggaacag ggcaaacaag gcgtctggct ggatttgccc accacaaccg aaacgctgca
    39961 agccgccctg cgggatgttg gcattactgc cgacaatccg caggattttt ttatcaacgg
    40021 gtattcctgc ccggaggaca gacaccttgc cattccctat gacatggtgc tggccgccga
    40081 cgtggacgag ctgaatttcc ttgccgcccg gctgggccag cttgacgccg ccgagatcgc
    40141 agagctgaac gccgccctgc aaaatccccg tggcggcttt gagaatatcg gccagatcat
    40201 cgactacacc gaaaatgtgg attactatgt gcatcttccc gacgttaggg gggatggaca
    40261 gttgggcgac tactacctga accgttccgg catggtggat atgccggagg aatggaaagc
    40321 cgggattgat acggcgcagt ttggacgcca cattgcccag caggaacaag gcgtttttac
    40381 ccagtacggc tatctggtga gaagcggcga cgaatggcag cgcgtccatg agggccagcc
    40441 ggtgccggag gaataccggg tgatgcacta cccccagccg gaagctgacc gggaggaacc
    40501 gcaggcccag cagccggagg catccgaaag ccccgacaaa gcgccgcccc cggttatccc
    40561 gatcatgctg gacggcatga acagcaaaga acgcatgaaa gtgattactg accgtctgga
    40621 aaccggcgta caggagcttt ttgaaagtag ccgctatatg gcttacttat ccgctatgtc
    40681 caagatgcac gattacagtc tgaacaatac gctgctgatc gccatgcagg gcggttcgat
    40741 tgtggcgggc tataacaggt ggcaggatga atttgaccgc catgtgaagc ggggcgagaa
    40801 aggcattaag atactggccc cggccccgtt caaggttaag cagcagatgg agaaaaccga
    40861 cccggccacc cagcagcccg tgatcggcgc ggacggcaag cccgtgaccg aagaacagga
    40921 agtgacggtt ccggccttta aggtggtgac agtctttgac atcagccaga ccgagggcaa
    40981 ggattttccc atgccctata tcagtgaact taccggcgac gtgcagcagt atcaggattt
    41041 ctttgccgcg ctggaacgga catcacccta tcccataagc attgagccga tttcagacgg
    41101 ggccaagggc cgctgcttct acgcaaaaca gcgcattgcc atcaacgagg gcatgagcga
    41161 attgcagacc ctaaagaccg ccatccatga gattgcccat gccaagctcc acgccattga
    41221 ccgggaggcc cccgccgagg aacaggcggc ccggccagac cgcagcaccc gcgaggtaca
    41281 ggccgaaagc gtggcctata ccgtctgcca gtattacggg ctggacacgt cggactattc
    41341 ttttggctat gtggccgatt ggagcagcgg cagggagtta tccgagctga aagcctccct
    41401 tgaaaccatc cgggccacgg ccagcgaatt gataaccgag atcgacggcc attttgccca
    41461 gcttcagcag gagcgcgagg cccggcagga acaggaggcc gtcacggttg acgttacccc
    41521 ggaggcagcg gccccggcgc aggccgagga agaacaggcc ccggcccttg atccggcagc
    41581 cgagccgctt gtgactgtgc tatggagcga aagcccccag ctaaaggacg gccagcaaat
    41641 gccgttgcat gaggccgacg cgctgtttgc ccgtctggat gcagcatatc cggcagaggc
    41701 aggctatgac aaaaccgcgt tccgcattga ctgtatcttt cagggcgagc cggacagcta
    41761 cgaggggcgg caggattttg gagataggga cggttccctg atcgaacata tccagagcta
    41821 ccaccaattt tacgcgcagg acgaaaactg gaaaaagcat gtaatcgcta caaccggcat
    41881 agagggctgg gagcaggaca aggcccatcg ggatatgctg ttaggcgagt ttgtccccta
    41941 tatgaagctg cattgcagcc ttgcccaaat ggaacagacg gcgcagggcc gcttacagtc
    42001 cggggaaacc ctgacgccgg aggaaacggc ctatttgggg gcgcttctct cttatgtgca
    42061 ggagtgccgc cccatgctca atcagggcca gtatcagttg ccggagccgc cgaaactggc
    42121 tgacttcgac cagagcttgc aggactacaa agcacaggta caggccgaga tcgcgcagga
    42181 ggccgccgca gccggtatga ccgtggagga atacgcggcg gctggctatg aagcacccca
    42241 acaggacacc ttttccatct accagcttcg aggcggggag gaaacccgcg actatcggtt
    42301 tgagccatac gagcgtttac aggccgcagg gctggccgtg gacagtgcca actatgacct
    42361 tgtttatacg gcaccgctgg ataaaagcac gtctttggag gatatttacc gcacattcaa
    42421 catcgaccac ccggcagatt ttaggggaca cagcctttcc gtttccgacg tggtggtgct
    42481 gcaccagaat ggacaggaca ccgcccacta tgtagacagc ttcggctata tggaagtgcc
    42541 ggagtttttg cgggaaaatc ccctgcgtac cgccgaactg tctacggagc agaacgaaaa
    42601 catgattgac ggcattatca acaatacgcc gcccgaaccg cagccggagg aacccgaaca
    42661 gctatctttt gaggatgtgg cagttgcttc cggccagaca caggaggaac ccccggaggc
    42721 tgcgcccccg caaacggctg tccgctatta tcccatcaat gagggagccg cccgccgcgc
    42781 caaggaagcc atgagctttt ctgactaccg gcccggcagc gccacggcgg aataccggca
    42841 ctatgtcgat caggccgtgg aaattgcgga gcgccagaaa aagcgtgtgg agccagagta
    42901 tcacgaaaag atagacagcc tccttgacac ctacgcccgc aagctggccg agaacatgaa
    42961 taagggctat gagattaccg cccgcgtccc ctctgtcctg attgccgggc cgtccaattt
    43021 cccggtacgg gcgaaagaaa agcagaacgc cgccagtgac cgcaacatgg aggaatttca
    43081 gtacattcag ggcttgcttg acaaaatccg cagcaccggc atgggtggta tcagcgccga
    43141 cgatccgcag gccgtttcca agctggaaaa gaaactggaa aagctggaag cgtcgcagga
    43201 gttgatgaag gccgtcaatg cctactaccg caagcatggg acgctggacg gatgccccca
    43261 tctgatcgaa agaggcattg aaaacctgaa agcggatatg gcgtcgggct ggcactatga
    43321 gaaaaaaccg ttccagtcct ggcagctctc caacaataac gccgagatac gccggttaaa
    43381 gggccgcatt gaggaattga cccgccaaaa ggaggcggcc tatgtgggat gggagtttga
    43441 cggcggcact gtggagatca accgggtggc caaccgcctg caaatcttct ttgaggggaa
    43501 gccggatgct gctgtacgcg acgagctgaa aagcaacggt ttccgctggt cgcccaaggc
    43561 cggggcatgg cagcggcagt taaacgacac cacaatccgc gtcgctgacc gtatcaagtg
    43621 catccagccc ctttccggcg aaaagcccag cgccttacag cttgcggccc gcagggagaa
    43681 agaaaagccc tctatccggg cgcagctcaa cgcggccaag accgaacagg ccaagcagcc
    43741 accggcgcgg gaaaaatcaa agggattgga ggtagagtaa atgcagaagt ttgaaaatgt
    43801 ggacgttctg gccgcgctgg aacagatcat gcggcagaac accgcgtttt atcaaagtga
    43861 ctttggcatt gacaaagaca ttatcaggcg ggatgccgcc agcgatcagg ccgcagacaa
    43921 gaccctgctc tggatgtccc ggccctccgg gacgtactgt ttccgggaac gtgatgtttt
    43981 cctgaaagac acccgacagt acaacacatg gaaattttac ggggagcaga cccgtgacaa
    44041 gatactggcc tacgcggtgg agctgaccgg cacacagggc ggcactatcc ggggcaatct
    44101 ctatgagctg gactatccgc agcatttccg gcacgtcatt gaaaccgccc agccggtgag
    44161 tgtgaaccgg ctcttttatg agcatggcac ccgtgacatc ccggagagcc agcgttttga
    44221 cggaagccct gaccgggtat tgggaaactt tttgtactat gaggcccagc cccatgaccc
    44281 ggctgtgctg caggaggcgc tacggacgga gcagcacagc cgggggcggg ccgtccccgg
    44341 cgatttcaaa gtccacgtca ccgctttgca tgacagccgg attgaaaccg aggcccggcg
    44401 tattgtggac agcctgaaag atctgtccgc gcctaacagc cccaataaaa cgcatttcat
    44461 ggtggagatc tccccgcact ttgcggcgat tgcttccacc aaggataatg accggctctt
    44521 tgccatgctg ccctataaat ccctgtgttt taccgggatg aaaggcaggc atggcgtgta
    44581 tgccgtgatt aaccgggacg agcgccggga tgtgagtatt cgcaggcccc ggccctctat
    44641 ccgcaagcag ctatccgaca gcaaacaggc cgccagccca aaaaaggcgg cggccagaac
    44701 caaaaagaat gaattggagg tataaggaat gatgcacttt accgtggagg aagaaaacct
    44761 gatctgtatg taccacaatg cagaccggcg cagaacgata aacaggctca ccgccgtcat
    44821 gccggttatg gatggggata tgcgggcgca ggcccagcag accctttcca agctggaacg
    44881 catgacggat gccgactatg acggccagaa gttccacttc acagacgaat aacgaacagc
    44941 agacgccggg cgcggcggcc atgtggtcgc ttgcgtccgg cgtcttttct ttttgcctat
    45001 tcctacgcat ttagaacccg gtattgtcgg ggataggatg aagtattcgc ttgcccctgc
    45061 aaacatgcgg gagaagcctt gcagcgggcg gttttcaatc ccttaaatgc gtaggttgca
    45121 gctataatta gacccctgaa acagatatag ccgcgcagcg ggtgtatctg tttcaggggt
    45181 gtgcaggtga tagccgcaaa gcggcgtaag agggtgcagc cctcttgccg tctatctctg
    45241 ttccagcggg aagctcggca atgcttccag cagtttcagg gaaatgcgct gccgtatatc
    45301 ttcgtcaatg actttcttct ttttgccgtt tgcctgtctg atctccaccg tggaaagctc
    45361 gttgatgtag tcagcataat gggccaacac tttttccgtg gcccacctct caccggcaac
    45421 ggcggctttg atcgtttcat agtccagcag cttttcttgt ccgtccatcc tgataccccc
    45481 gtcagactga ttttttctat gataccatat tcggaagcat ggaaccagag aaaacggcgc
    45541 ttttctgctg gtaaattcta cgcatttaga acagcacttc ggcggggata ggataaaaca
    45601 cccacatacc ccgctgacca tgccggaaaa gccttgaaat ataagggctt ttacagctct
    45661 aagtgcgtag gtttccagta tcttttccgc tggcgctcgg cctctttgcg gcggcgcatc
    45721 cgtttggagc aggccgcgca gtatttggcc cggttagact tcggcgtgaa cgtggccccg
    45781 cactcacagc agcgtttcac ttcgtcccgg tctttggtga tctcggcata cagggccgca
    45841 tccagcggga ggacagcggc cttaaaccag cggcacagaa gcgaatagga aatgctctgt
    45901 acgcaaatac attcttcgcc gtcgtccagc aacaggcagt tgccgtcaca atagttgcag
    45961 cactcatgcg tcagcttccg ggccttgcga tattgagggt aattcattcg tggaatactc
    46021 atagctcttg cgtccattcc tttcccggcg tcatacgcaa aatgccgtcc acattctgct
    46081 tgatgatgcc gtattcctgc atctgctttt tcgcttcgcc gtacttctca tacagccgtt
    46141 ccttttcctc ggccaatcgc ttgtactcgg ctttcagggc gtacagatcg gggagctttt
    46201 tcacaccctg tccctttagg gcctttgccg cagcttcata caaaatcaac gtgctttcat
    46261 gctcacgccg gaattttgcc ttatccgctg cattgcggta ttccatagcc acgggccaga
    46321 gctgcttgta ggtagaaata ttctttatca gcaccgccat atccgcaagc cggtgttcca
    46381 tagctttgag ggtagcggcg gcctcgtcgc tggcggcggt gatctcggcc actttgcttt
    46441 ccaaatccgg gtaggtgtct atcccatgtt cagtcaggaa attcaaagtc tttgcggcct
    46501 gcttcaaatt gtggagcttc gcccacctct catagcctgc cgactgctgg gccttaatgt
    46561 tgttttccag atcaatccgc aaagaaatcc ccttgcgctc tttgggcgct ctggtgataa
    46621 cgcggccttt gatacgctct ttgatggctt cctcggtgta ggcttccccc aatgtcttgc
    46681 agcgggtaaa gcgttcctgt ccgggagcgc ggaaagaaat aaactttccc ggcttgatct
    46741 catagccctg cgcctgcatg agccgcagga aatcatcaaa atcttttgcc tgcgggatag
    46801 cggcgtcaat ggctgctttg agcttcgctt tccagctcgt ccctttccgc tgggcgtccc
    46861 actcggcata gctcttgccc ttactctggc cgggcttcac cacggacaat ccgttttcct
    46921 tgcacagcct gtcgctggtg cgccggatat aggcatagct ctgtttgttg gaaatgtact
    46981 tgcgctgatt taccatatcc acggcacaga aaataatgtg attgtggacg tggcccttat
    47041 caatatgggt agtcagcaca tagggatatt tcccttgcag cacttcctcg gcaagctgct
    47101 tcccgatctc atgggcctgt tccggcgtgg cttcgccggg ggcaaaggat tgtatcaggt
    47161 ggtggcccag attattgccc ttttggtatg cctgcgccag cagcatttca aattcaatgt
    47221 ccgctgtttc ataagagcag gcaaaggagg ccaccagcag cttgccgtca gttttgtccg
    47281 ggttctcgat gtagtcaagg gcttttttca gcgttgactt gataggatgt atctttgtaa
    47341 ctgccatatc tgcgccagcg ccccctttat atcctcgatg tcctgtgcgt acaccggccc
    47401 cataccgttc agcctctttg caatctgatt gacgttgacg ccgatcttct gtatctcggc
    47461 ggtctgcgcc cggatgtcgc tggtgtccat gttgacgata tagccgtcaa tgagcatctt
    47521 ccgggcgtag gctgaaaagt tcttcgtatg cagcagcgcc attttctgtt caatcatagc
    47581 ccgttcctcc ggcgtcacag ggacgcgcag cacgattttt cgctttctgt ttgccatgct
    47641 tcaccgtcct ttccattcag gggtttgggg atttccccaa caagcaaaac ggacgcggcc
    47701 cggcagggac ggggcaggcc gtttttccgg gagtggctac actccctatg cttgctacgt
    47761 tactgtttct ccactaacaa gacgtttcca aagccccaaa ctacccgcaa aatagccctc
    47821 tggaaagaaa aaagtgcaaa aaaatagaag ctacgctgtg cagctcccgc taaaagtaaa
    47881 acagaggatg ccagttacac atcctccgtt tcattcttct tcggcttttc aattagtatg
    47941 gcgctgtcaa tcgcgccctc gatgatcggc aggtattctt cggggcagag tttcagcttg
    48001 tggctgaccc tttgccgcag ttcgctttcc tcccgcatga tctccgggtt aaagtagcgt
    48061 tccacaggaa gcccgcaggc tttaataagc tgtatgacaa ccggcagact gggaatggcc
    48121 cgtcgttttc gatgttggca agatagcgcc agtcaatatt tattttctct gccattgctt
    48181 tgcgcgaaac gcgctttgct tgccgggccg ctttcacatc cgcgccgaaa gtttcaaagc
    48241 cgggacaatc ttcaatattc gccatatcgc acctcccact tacattgtat atttcatact
    48301 ctgcccgtgg aatgttggta tatgcacctt tcttaaagtt tatatttcac attttgtttc
    48361 ttttattctt cgagcaaaag aattataatg taccctgtgg aggtgtacta tggactacat
    48421 gacgttgaaa gaggcaggcg agaaatgggg tgtgccccca cgatggataa actactattg
    48481 tgctgcggga cgcatccccg gcgctgtaaa gatggcgacg atctggctca ttcccaaaac
    48541 tgcggaaaag ccgattgaca ggcgtacaaa gaaaggaaag gcggttactg aatagtataa
    48601 tgaaaccggc gcattttgga tatggttttg aagagagaga aagcatggta ttttgtcacg
    48661 gaaaaactat aagatgatag atggcaggct gctccagacc gataaaaagt attctcatct
    48721 gaaacagaaa gaaaagattt acacatggat gtatgaagaa gcgaaacttt atcatgacag
    48781 aaatggaaaa tgcccgaaac aaagacgagg aagctgctgc tgtatcagcc gtatatggta
    48841 gaattgaaaa ggccggcatc tggattcttt atggtgaagt ctccagacat tggataactg
    48901 ctggtctaat gcgcctttga gtatggggtg attgatttta ataccgggga ggtacggctt
    48961 tttgaggaaa atattctggg atttacattt ggcgattatt acatttcctg taactgcaag
    49021 gacacggatg atgaagatat gaggaatata gacttgctga ttttctactg tcttgaacgg
    49081 tattaggact gaatctgctg cgcggagtgc ggcaagagcg accggaggga gtacacacag
    49141 gccctgcctg tgtgaaaagc cataccgcaa ggtgcattcg caaaaaagag gccgcgcatt
    49201 ttgctgaggc ttggggtgtc cccaacaagc aaaacgagaa cgccgcaggc gggcaagtgg
    49261 tggatcagaa tatccgtaaa ggatattctg atccattgct tgccagtatt atcgggatgt
    49321 tttgacaacc gctgtaatcg aaacatccca aacattaaga aggtgttaat tattattatc
    49381 ttgatttaat tcgtttaaac caataatata gatacataca ccatgaaaag aagcgagtat
    49441 cccaatgacg gatgattaaa atccgaaaag aaatcgcttt gaaactacag ggaaactaca
    49501 gactgttatg ttatcttctt aaaatggagg gatttttatg tcgatacgaa ttctacttgt
    49561 cgaggatgat gatcatatct gtaatacagt aagggcgttt ctggctgagg caggatatca
    49621 ggtggatgcc tgcacagatg gaaatgaggc atacaccaag ttttacgaaa acacttatca
    49681 actggttatt cttgatatta tgctgcccgg tatgaacggg catgaacttt tgcgtgaatt
    49741 tcgtgcgaaa aatgatactc ccattctgat gatgacagcc ctgtcggatg acgaaaacca
    49801 aatccgggcg tttgatgcag aggcagacga ctatgtaaca aagccattca agatgcagat
    49861 tttactaaag cgggtggaag ccctgctgcg gcgcagcggt gcgctggcaa aggaaatccg
    49921 tgtcggcagg ctgacacttc tgccggagga tttcacggta ctttgtgacg gtacagagct
    49981 gcccctgaca cgaaaagaat ttgaaatcct tttgctgctg gtgcagaaca aaggcagaac
    50041 cttaacgcat gaaatcattt tgtcacgtat atggggatat gactttgagg gtgatggcag
    50101 cacagtccac actcatatca aaaatttgcg ggccaagctg ccggaaaata tcatcaaaac
    50161 cattcgcggt gtaggatacc gattggagga atcataataa tggaaagaaa agggattttc
    50221 attaaggttt tttcctatac gatcattgtc ctgctactgc ttgtcggtgt aacagcaaca
    50281 ctgtttgcac agcaatttgt gtcttatttc agagtgatgg aattacagca aacagtaaaa
    50341 tcctatcagc cattggtgga actgattcag aatagcgata ggcttgatat tcaagaggtg
    50401 gcagggctgt ttcactacaa taaccaatcc tttgagtttt atattgaaga taaagaggga
    50461 agcgtactct atgccacacc aaatgccaat acatcaaata gttttagacc caactttctt
    50521 tatgtggtac atagagatga taatatttcg attgttgctc aaagcaaggc aggtgtggga
    50581 ttgctttatc aagggctgac aattcgggga attgttatga ttgcgataat ggttgtattc
    50641 agccttttat gcgcgtatat ctttgcgcgg caaatgacaa cgccgatcaa agccttagcg
    50701 gacagtgcga ataaaatggc aaacctgaaa gatgtaccgc cgccgctgga gcgaaaggat
    50761 gagcttggcg cactggctca tgatatgcat tccatgtatg tcaggctgaa agaaaccatc
    50821 gcaaggctgg aggatgaaat cgcaagggaa catgagttgg aggaaacaca gcgatatttc
    50881 tttgcggcag cttctcatga gctaaaaacg cccatcgcgg ctacaagcgt tctgttggag
    50941 ggaatgcttg aaaatatcgg tgactacaaa gatcattcta agtatctgcg cgaatgcatc
    51001 aaaatgatgg ataggcaggg caaaatcatt tccgaaatac tggagcttgt cagcctgaat
    51061 gatgggagaa tcgtacccat agctgaaccg ttggacatag ggcgcacggt tgccgagttg
    51121 ctgcccgatt ttcaaacctt ggcagaggca aacaaccagc ggttcgtcac agatattcca
    51181 gccgggcaaa ttgtcctgtc cgatccgagg ctgctccaaa aggcactatc caatgtcata
    51241 ttgaatgcag ttcagaacac gccgcaggga ggcgaggtac ggatatggag tgagcctggt
    51301 gctgaaaaat gccgcctttt tgttttgaac atgggcgttc acattgatga tactgcgctt
    51361 ccaaggatgt tcaccccatt ctatcgcatt gatcaggcgc gaagcagaaa aagtgggcga
    51421 agcggtttag gacttgccat cgtacaaaaa acgctggatg ccatgagcct ccagtatgcg
    51481 ctggaaaaca cctcggatgg cgttttgttc tggctggatt taccgctcac atcaacattg
    51541 taaatattta aaacttaaat gattttgggc tctttgtcaa ataggactga tagagtgaga
    51601 taagaacatc taaggtagaa ttccttttct actttagatg ttttttgatt cataggtaat
    51661 cagattattt agtaagaaaa ttctggtctt cattttccga aagcttcgaa agccataagc
    51721 gactcgtttc aatgctttga tgtgggtatg cagattttct attttggcat ttgaataagg
    51781 caattcgagg gctaaacgaa tgccggattc atagtttata aaagcttttt ttatagaatg
    51841 cagttctttt ggaacggaat tgggcatcgt tcttacaagt ttaaagaaag tgtccgcctc
    51901 tttgtcgtga aacgcttgaa gaatttcttg atagtaaaaa taggcgattc gtaattcgtc
    51961 agagatcgaa agcagacgat ccaccacttc actttcggtg agatacgccc aaccaaaatt
    52021 gcgccatttg gtccatttgt cataaacaag cttgtcctgt cgtttgatca gaagccgaga
    52081 caacgccttt aattgtcgat aatatttggc ttgtgttgga tcgtttcgat caaagctttt
    52141 catgattcgt acgcgaatat cctcaaattt acgaatgaga tgtttgacaa tgtgaaaacg
    52201 atccacaacg agttttgcct ttggaaaaca ttcctttatc agagaggcat aagaaacatt
    52261 catgtccgtc acgatgacct ttaccttcaa tcgtgcgcgt cgttcaaatt gcataaaata
    52321 agaaacgaga gcctttttct tccgtgaagg aagaatatcc agtaattttc cagtatcgcc
    52381 atccatacaa gaaaaggagt agggaccgac ttgatttttc agtgaacgaa attcatccat
    52441 taataaacaa cgcggtaacc aatttctttt tacttttgtc atggggatca gagaagcgag
    52501 tgtccgagaa acggtcgacc aagaaacgcc gcaatgctta gcaattgtcg tcattgcttg
    52561 tttttcagtt agctcttcta aaattttata gcgcacttgt ttagcgataa agcagtttct
    52621 atcgacaatg taggtattcg ccgtaaaata ggtgtggcag ccacgacagt ggtagcgttg
    52681 tttcgctaaa gcaagataag tcagttggtt cgcacattta ttaagttgaa tgagcgattt
    52741 tttctttccg ttcttaacga tcatgccttc atgattcatc tgtttacaca aaggacagcg
    52801 acgaatttct ttacttaacg tcgcagaaac aacaagactc ttgatattct taatgctctt
    52861 cgattccaca tttgtgatga aaatgttttt atctttgatt ccaagtagta gtttgatatg
    52921 atgaagatca ggcatacaga acgctccttt gattgtgttg tggtgattca attctaacgg
    52981 agcttctgta tgttttgttt tttcatgctc aaaagggacc gatagaatga ttttctatc
//
LOCUS       DACCVH010000009        52350 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.009, whole genome shotgun sequence.
ACCESSION   DACCVH010000009 DACCVH010000000
VERSION     DACCVH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.009"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(122..499)
                     /locus_tag="IVV98_000619"
     CDS             complement(122..499)
                     /locus_tag="IVV98_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806297.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /locus_tag="IVV98_000620"
     CDS             755..1483
                     /locus_tag="IVV98_000620"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP7806298.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="IVV98_000621"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="IVV98_000621"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP7806299.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="IVV98_000622"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="IVV98_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP7806300.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="IVV98_000623"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="IVV98_000623"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP7806301.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /locus_tag="IVV98_000624"
     CDS             4618..6057
                     /locus_tag="IVV98_000624"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP7806302.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6089..7132
                     /locus_tag="IVV98_000625"
     CDS             6089..7132
                     /locus_tag="IVV98_000625"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP7806303.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="IVV98_000626"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="IVV98_000626"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP7806304.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="IVV98_000627"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="IVV98_000627"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP7806305.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="IVV98_000628"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="IVV98_000628"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP7806306.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="IVV98_000629"
     CDS             10651..11565
                     /locus_tag="IVV98_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP7806307.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="IVV98_000630"
     CDS             complement(11698..13263)
                     /locus_tag="IVV98_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7806308.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="IVV98_000631"
     CDS             complement(13256..14707)
                     /locus_tag="IVV98_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7806309.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="IVV98_000632"
     CDS             complement(14721..15737)
                     /locus_tag="IVV98_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7806310.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /locus_tag="IVV98_000633"
     CDS             15957..17045
                     /locus_tag="IVV98_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7806311.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /locus_tag="IVV98_000634"
     CDS             17099..18625
                     /locus_tag="IVV98_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP7806312.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /locus_tag="IVV98_000635"
     CDS             18627..19832
                     /locus_tag="IVV98_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806313.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="IVV98_000636"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="IVV98_000636"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP7806314.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="IVV98_000637"
     CDS             21330..22754
                     /locus_tag="IVV98_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP7806315.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="IVV98_000638"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="IVV98_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP7806316.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="IVV98_000639"
     CDS             24327..25304
                     /locus_tag="IVV98_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP7806317.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25329..26972
                     /locus_tag="IVV98_000640"
     CDS             25329..26972
                     /locus_tag="IVV98_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP7806318.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26980..28386
                     /gene="lpdA"
                     /locus_tag="IVV98_000641"
     CDS             26980..28386
                     /gene="lpdA"
                     /locus_tag="IVV98_000641"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP7806319.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28548..28823
                     /locus_tag="IVV98_000642"
     CDS             28548..28823
                     /locus_tag="IVV98_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP7806320.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28829..29596
                     /locus_tag="IVV98_000643"
     CDS             28829..29596
                     /locus_tag="IVV98_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP7806321.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29764..31593
                     /gene="typA"
                     /locus_tag="IVV98_000644"
     CDS             29764..31593
                     /gene="typA"
                     /locus_tag="IVV98_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP7806322.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31854..33626
                     /gene="recQ"
                     /locus_tag="IVV98_000645"
     CDS             31854..33626
                     /gene="recQ"
                     /locus_tag="IVV98_000645"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP7806323.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33740..34042
                     /locus_tag="IVV98_000646"
     CDS             33740..34042
                     /locus_tag="IVV98_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP7806324.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34045..35208
                     /locus_tag="IVV98_000647"
     CDS             34045..35208
                     /locus_tag="IVV98_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP7806325.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35234..38662
                     /locus_tag="IVV98_000648"
     CDS             35234..38662
                     /locus_tag="IVV98_000648"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP7806326.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38683..39807
                     /locus_tag="IVV98_000649"
     CDS             38683..39807
                     /locus_tag="IVV98_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806327.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39797..40234
                     /locus_tag="IVV98_000650"
     CDS             39797..40234
                     /locus_tag="IVV98_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP7806328.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40218..40556
                     /locus_tag="IVV98_000651"
     CDS             40218..40556
                     /locus_tag="IVV98_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP7806329.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40675..41235
                     /gene="rsmD"
                     /locus_tag="IVV98_000652"
     CDS             40675..41235
                     /gene="rsmD"
                     /locus_tag="IVV98_000652"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP7806330.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41232..41723
                     /gene="coaD"
                     /locus_tag="IVV98_000653"
     CDS             41232..41723
                     /gene="coaD"
                     /locus_tag="IVV98_000653"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP7806331.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41713..42756
                     /locus_tag="IVV98_000654"
     CDS             41713..42756
                     /locus_tag="IVV98_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP7806332.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42915..43643
                     /locus_tag="IVV98_000655"
     CDS             42915..43643
                     /locus_tag="IVV98_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP7806333.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43759..44004
                     /locus_tag="IVV98_000656"
     CDS             43759..44004
                     /locus_tag="IVV98_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7806334.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44001..44219
                     /locus_tag="IVV98_000657"
     CDS             44001..44219
                     /locus_tag="IVV98_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP7806335.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44355..44894
                     /locus_tag="IVV98_000658"
     CDS             44355..44894
                     /locus_tag="IVV98_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP7806336.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44887..47160
                     /locus_tag="IVV98_000659"
     CDS             44887..47160
                     /locus_tag="IVV98_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP7806337.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47198..48244
                     /gene="holA"
                     /locus_tag="IVV98_000660"
     CDS             47198..48244
                     /gene="holA"
                     /locus_tag="IVV98_000660"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP7806338.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48333..48587)
                     /locus_tag="IVV98_000661"
     CDS             complement(48333..48587)
                     /locus_tag="IVV98_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP7806339.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48987..49256)
                     /locus_tag="IVV98_000662"
     CDS             complement(48987..49256)
                     /locus_tag="IVV98_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806340.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49726..50181)
                     /locus_tag="IVV98_000663"
     CDS             complement(49726..50181)
                     /locus_tag="IVV98_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP7806341.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50319..52247)
                     /locus_tag="IVV98_000664"
     CDS             complement(50319..52247)
                     /locus_tag="IVV98_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7806342.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT        17193 a         9005 c        11418 g        14734 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc gcagaaggtg
    25381 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    25441 aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga acggttaaaa
    25501 atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta gaaatcgatg
    25561 caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc caaactccag
    25621 ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca agcgaaggag
    25681 tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat
    25741 ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa gttcaaaatg
    25801 acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac gtgattgttc
    25861 cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct cctggacaca
    25921 atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat
    25981 caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg gctatgccat
    26041 ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact gcaactggaa
    26101 aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg
    26161 caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct cctgcagcag
    26221 aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac ttggaagaac
    26281 gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac agtaagcata
    26341 cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg gataatcgga
    26401 aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg ccatatgtcg
    26461 tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct atcgacgatg
    26521 caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact gatacggatc
    26581 acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt gctattgcag
    26641 acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca gaagatatgc
    26701 gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg tttacaccag
    26761 tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa caaccaatcg
    26821 taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc
    26881 accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa cgtcttttag
    26941 ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg agattttgct
    27001 gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc tgccatccgc
    27061 gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg cggtgtttgt
    27121 ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca ttatcaagag
    27181 tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa
    27241 acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt tggtttccta
    27301 ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca
    27361 ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc aatcatcgca
    27421 acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt gttagattct
    27481 actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg tggcggtgtg
    27541 attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac gattcttgaa
    27601 ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt agaagatgat
    27661 ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac
    27721 ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt tactgctgat
    27781 tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt agaacaagcg
    27841 ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg tacgaacgta
    27901 cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca caaagccagt
    27961 tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt agattataaa
    28021 gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat gacgatcaaa
    28081 gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc agggaacggt
    28141 cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac gatcgaagat
    28201 aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta
    28261 gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat tcatcctcat
    28321 ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt accaatccat
    28381 atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta
    28441 gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg gtttattacc
    28501 acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg caagaatatc
    28561 agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg aagatgtggg
    28621 aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg aagacttatc
    28681 agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga cgggaatttg
    28741 aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca
    28801 aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata tcaagtcctg
    28861 gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa
    28921 atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt ttctaatcga
    28981 aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag ggtgtaatca
    29041 attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca ccttgaattt
    29101 tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg gcgttggaaa
    29161 gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa aaggaatagg
    29221 cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat cggaaggctt
    29281 acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag aaattgcgga
    29341 aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg caatcttgaa
    29401 aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag cgggaaatgt
    29461 cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt tgacatttga
    29521 aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg cagacctttt
    29581 gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa
    29641 agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa aagtctgcta
    29701 taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa ggagttagtt
    29761 acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga
    29821 aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc acatacgcaa
    29881 ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta
    29941 gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga tactccagga
    30001 cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg
    30061 gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa aaaagcactg
    30121 gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc tgctcgtcct
    30181 gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga tgatgatcag
    30241 ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt gtcagatgat
    30301 ccagcagatc aagaaccaac catggcacct atttttgata caattattga aaaaatccct
    30361 gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact tgactacaac
    30421 gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa agtaggagac
    30481 caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac gaaattattt
    30541 ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga cttgattgct
    30601 gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat
    30661 gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt agttaataat
    30721 tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga agaacgtttg
    30781 atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc tccagatgca
    30841 tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa catgcgccgt
    30901 gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat cgacggtgta
    30961 aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat gggtagtgtt
    31021 atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac aggaaacgga
    31081 caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc aactgaattc
    31141 ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata tctgccaatg
    31201 cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa
    31261 gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt
    31321 acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga tttgactgtc
    31381 aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga ccaaacatct
    31441 gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt gaatgatgat
    31501 gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt agagaaaaat
    31561 gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag agagaaacca
    31621 gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt ggagaagtca
    31681 tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa
    31741 aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga aaggagatca
    31801 acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg
    31861 acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa gaaattatcc
    31921 agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt gggaaatcaa
    31981 tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg tcccctttaa
    32041 tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc gccactttta
    32101 tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc gatagacagc
    32161 agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt atccaagcaa
    32221 tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc tctcagtggg
    32281 ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa ctgccaaatc
    32341 gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct gacataaaaa
    32401 gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga gaaaatctac
    32461 gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat ttaaagatca
    32521 acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac cgtctctatc
    32581 atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta aatgagaatg
    32641 agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt gtagcgacaa
    32701 atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat tatcaaattc
    32761 ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat ggtctttcca
    32821 gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt tttatccagc
    32881 agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa gcgatgacag
    32941 aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt ggcgagacaa
    33001 gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta gaagtaacga
    33061 cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa
    33121 tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta ggttttggac
    33181 atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg
    33241 aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct gttttgaaag
    33301 taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga aaggaaccca
    33361 agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg ctgcgggaac
    33421 tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt tcagattcca
    33481 cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt cagataaaag
    33541 gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg ataaaaaatg
    33601 cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa taaaaacaac
    33661 tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat taaggaatta
    33721 gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa
    33781 tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc tctgtatctc
    33841 acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt cccggcaagt
    33901 cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga tgttaagtga
    33961 gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt atgataaaaa
    34021 agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca tctattagac
    34081 tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat ggtatatagt
    34141 tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt cattaaccag
    34201 agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat gaaaacagat
    34261 gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat tttgctgctg
    34321 attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca aattgcagga
    34381 ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct gtctctgact
    34441 ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa acgtccactt
    34501 gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg taatgcggca
    34561 gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta tgtgtatact
    34621 ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct gatcaatatc
    34681 acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt tgctatttac
    34741 caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg ctactatgcc
    34801 atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa aaaaggattt
    34861 ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact gggagtgatt
    34921 atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt ccttgtaggt
    34981 atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc aatgtttttg
    35041 atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac agggatcacg
    35101 ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg tgtcggcttt
    35161 gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata aaaaaagatg
    35221 taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt
    35281 atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag aagaagatga
    35341 atattccgta caccgtttca aagcggatga agcatattta gtaggacaag gaaaaaaacc
    35401 gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat gcggagctga
    35461 cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga
    35521 agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt ttggagataa
    35581 aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag gcacagatgg
    35641 accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt atccgattat
    35701 gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg atgaaaagag
    35761 tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga
    35821 agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga ttctcgggga
    35881 tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc gccgtcacca
    35941 aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg
    36001 ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt
    36061 tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc aagtggaaca
    36121 tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt tgattgctca
    36181 aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta aattaaatgg
    36241 ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt taccagacac
    36301 agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg atgtcggaaa
    36361 tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa aagtatgtac
    36421 gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga aagaatttag
    36481 aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac atcctgaatt
    36541 ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat ttgaatttcc
    36601 tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg
    36661 ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga
    36721 tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga agggtgccga
    36781 tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata cgacatttag
    36841 agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca agcagattgc
    36901 acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg ggggagcaac
    36961 atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga gaaaaattcg
    37021 ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta
    37081 ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag cgcaaggaat
    37141 cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa aaagtatcca
    37201 agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg gcgatatcaa
    37261 cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa aggaactaga
    37321 acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta aaccgcaggc
    37381 agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc atctgcatac
    37441 tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag caggagtaga
    37501 catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta gcatgagcag
    37561 cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg aaaatgcaca
    37621 gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg aaaacggctt
    37681 gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt attcgaatct
    37741 acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca aacaaatgta
    37801 tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat ctaaagtagt
    37861 tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata tttatgaaaa
    37921 aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag aactagggca
    37981 acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca gacctgcatt
    38041 gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt
    38101 ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt tgatgtatcc
    38161 gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta cattactgga
    38221 cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg
    38281 cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg aagggaatcg
    38341 cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag ataattcgat
    38401 catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac aaattggagc
    38461 aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg
    38521 tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag cacgttttga
    38581 cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg gtgacctttt
    38641 gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag actgggtttg
    38701 ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt cttgtttccg
    38761 ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat gacaacgtgg
    38821 aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc gatcgatcag
    38881 ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg ttttgaaaca
    38941 agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca agacagcaga
    39001 gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg
    39061 atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac ttttgagtac
    39121 catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg tccgctaatt
    39181 gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa cggcctattt
    39241 tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca agtgtttggt
    39301 gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat caatcgcgtt
    39361 aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga acttcccata
    39421 tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga ttttttgaca
    39481 aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc gctaggcagt
    39541 gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt aatcagtaaa
    39601 caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc tactttttcg
    39661 tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc gggaacggat
    39721 tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga agaaaacgga
    39781 gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg atcaatgcct
    39841 ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg aacataaaca
    39901 gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga
    39961 agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg aaaaaaaacg
    40021 agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag ctttccgata
    40081 tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg ccgaagaagt
    40141 ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa aacactttgg
    40201 atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca aaacgacgcg
    40261 ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt
    40321 tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa gagacattgg
    40381 aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa cgttcttacc
    40441 gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta ttaaaagacg
    40501 aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat ctttaaaaat
    40561 ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt ttgatcattg
    40621 tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga gtagatgcgg
    40681 ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga
    40741 ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata ttttgatgga
    40801 gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc agtatctaga
    40861 ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat catcaaagaa
    40921 aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga tgcggacaaa
    40981 gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct tgatccgcca
    41041 tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg acttttttct
    41101 aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga aactgtggct
    41161 ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat ctatagaaaa
    41221 gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt acaaaaggtc
    41281 acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt ggtgttttta
    41341 tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg atcacaaaag
    41401 ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa
    41461 cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc aaagactttg
    41521 aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg gaaactgtct
    41581 tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa gaagtactgc
    41641 actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct ttagctggaa
    41701 agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat catatttgga
    41761 atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc accgggagcc
    41821 acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg ttctgggtct
    41881 ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa
    41941 atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc gacaaatgaa
    42001 gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc aatcgaacaa
    42061 gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata tgtcatgagt
    42121 gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt aacaaaagta
    42181 gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag ccaaaaagtt
    42241 ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc ttctggtgat
    42301 ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac tgaccatacc
    42361 gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg gccatcagcg
    42421 ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt gcgacatggt
    42481 aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg aatcggagga
    42541 atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt tgcaccagat
    42601 gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa
    42661 gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta
    42721 caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa agaggggttg
    42781 tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa
    42841 acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag agctcactgt
    42901 ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc tttgaaaaaa
    42961 gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg atcatttgga
    43021 tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca aatttgctat
    43081 tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt agttccagtg
    43141 gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt
    43201 acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct tcagaagaac
    43261 gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat agcgatcgaa
    43321 tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct gtaggtgaag
    43381 agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct acagcagatt
    43441 ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag cagattcctg
    43501 ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac ggatccttcc
    43561 agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt gaaaaactaa
    43621 aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc aataaatgga
    43681 cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag gaggtagtat
    43741 ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc aatgctgaat
    43801 gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt cagcggcaat
    43861 aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac agcagataaa
    43921 gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc taaagaaacg
    43981 taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt tctgatcatg
    44041 ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg aataacaagt
    44101 tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat tgtgaagtat
    44161 cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata atgggctaat
    44221 ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg
    44281 ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg
    44341 gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag
    44401 ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg gctcaggcag
    44461 tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca ctcgttcgag
    44521 aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc cactgcatag
    44581 atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca gagatgaatg
    44641 cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc tatgtcacac
    44701 attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt
    44761 atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat
    44821 ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat gaattaacag
    44881 gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt tccggcaatt
    44941 acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg tttgcttctt
    45001 gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt
    45061 ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt tttagaggaa
    45121 aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa tggtaatttt
    45181 ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc ttatcaagta
    45241 aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat agaattgact
    45301 gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt tgaccaagaa
    45361 gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat tgaacagatc
    45421 accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt tatctccttt
    45481 gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt atggggctat
    45541 aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt gctgcatctg
    45601 ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta tttgtttcga
    45661 cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac tatctgttat
    45721 gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga
    45781 ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc agttgtcttt
    45841 tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca gcttagtttt
    45901 ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa aaaaacggcc
    45961 tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt ttatgagtgg
    46021 cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt tctttttctt
    46081 cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt acttttgctg
    46141 atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg gtcgtctctc
    46201 attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt actgatttgt
    46261 atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct tttttctttt
    46321 atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat cgatgtcggt
    46381 caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt gatcgatact
    46441 ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg tcctcctgct
    46501 gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga taaactcatc
    46561 ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca gcattttact
    46621 atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca aaggcattta
    46681 tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga caggatcagc
    46741 ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag aaatgaagat
    46801 tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg agatttgaat
    46861 caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa
    46921 ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca tattgaagca
    46981 aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca cagcgaagta
    47041 ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca aggaatgatc
    47101 acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat gatagactag
    47161 taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt tgagtataca
    47221 agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga ttttaggaac
    47281 agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc aattagaggg
    47341 cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag atgaggtagt
    47401 agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg tagagaatcc
    47461 ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg atttattgac
    47521 ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc catatgaaaa
    47581 gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta tcatcaatgt
    47641 ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag agaattcctc
    47701 aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact tagatttatc
    47761 caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac agcaaatcac
    47821 ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt ttgacatgac
    47881 ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag atttagttat
    47941 gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac gtttattttt
    48001 acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg aaacattgaa
    48061 aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg atgaacattt
    48121 gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa cgggacaaat
    48181 cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt taagaaatcg
    48241 ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg
    48301 acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt gcttaaacga
    48361 gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc catatcaata
    48421 gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc tacagcatct
    48481 tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt cacattagcg
    48541 ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag tttcacctcc
    48601 gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt atacctaaag
    48661 gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct tttattagga
    48721 ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg
    48781 gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa agtttgaatg
    48841 ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag ttttttttga
    48901 aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca gttattttat
    48961 aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt aatgtattca
    49021 tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt ccatttgcca
    49081 cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc caaatagcga
    49141 tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc agtcagcatc
    49201 attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt ttccacaagc
    49261 gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat tttgatattc
    49321 gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata acaaaaaaga
    49381 gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca ttggcacggc
    49441 ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc atcccctata
    49501 tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa atcaggaaat
    49561 aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc gattgttcct
    49621 atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat cacggatcag
    49681 taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc
    49741 aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg cggcgattcc
    49801 tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc
    49861 agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac cgcaaaaaac
    49921 agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac cgatttctcc
    49981 tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat tgattccttt
    50041 gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa tcaaaacaaa
    50101 agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta aaataattcc
    50161 taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca atcataacat
    50221 gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat aagctgtttt
    50281 tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga agacagccgc
    50341 gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc aggtaaaggt
    50401 cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg tcctacaact
    50461 ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag aataacaaga
    50521 atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag ccgatgactg
    50581 tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc catagcggca
    50641 tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg cgcatcattg
    50701 actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt gactagttgt
    50761 gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg ttcagcaatg
    50821 gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt ttgggattta
    50881 aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc taaaacagca
    50941 attaactgct gatctttaga aagataaatc acggttttgc cttgattttc caaacgttcg
    51001 atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc gtgcttgcca
    51061 actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat ttcttctatt
    51121 ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat cgcatgagca
    51181 agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa atccttttca
    51241 tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc tgttttatca
    51301 aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt gattaaaatc
    51361 ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga tgcgacaagc
    51421 gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc atcccaactc
    51481 caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa aatcaatttt
    51541 acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt attctgcgct
    51601 tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt tgttactcga
    51661 atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc taaatatttt
    51721 tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg tgtgctttct
    51781 aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt atccaccttt
    51841 agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg ggctttttgt
    51901 ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt gtattcctct
    51961 aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta attaccgatc
    52021 aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt ccgatcattc
    52081 cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat ggcactgata
    52141 taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa gatcataaat
    52201 aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt tattagacct
    52261 ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac agctaaatga
    52321 gaacgataat ggttatcatt tggtgattaa
//
LOCUS       DACCVH010000010        50293 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.010, whole genome shotgun sequence.
ACCESSION   DACCVH010000010 DACCVH010000000
VERSION     DACCVH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.010"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(99..1229)
                     /locus_tag="IVV98_000665"
     CDS             complement(99..1229)
                     /locus_tag="IVV98_000665"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP7806343.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IVV98_000666"
     CDS             complement(1878..3080)
                     /locus_tag="IVV98_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7806344.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IVV98_000667"
     CDS             complement(3140..3343)
                     /locus_tag="IVV98_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP7806345.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IVV98_000668"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IVV98_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IVV98_000669"
     CDS             4880..5692
                     /locus_tag="IVV98_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806346.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="IVV98_000670"
     CDS             complement(6716..6868)
                     /locus_tag="IVV98_000670"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806347.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="IVV98_000671"
     CDS             complement(7059..7937)
                     /locus_tag="IVV98_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7806348.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="IVV98_000672"
     CDS             complement(7976..9094)
                     /locus_tag="IVV98_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP7806349.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="IVV98_000673"
     CDS             complement(9091..11190)
                     /locus_tag="IVV98_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP7806350.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="IVV98_000674"
     CDS             complement(11241..12062)
                     /locus_tag="IVV98_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7806351.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="IVV98_000675"
     CDS             complement(12059..12868)
                     /locus_tag="IVV98_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7806352.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="IVV98_000676"
     CDS             complement(12889..13383)
                     /locus_tag="IVV98_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7806353.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="IVV98_000677"
     CDS             complement(13395..13883)
                     /locus_tag="IVV98_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7806354.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="IVV98_000678"
     CDS             complement(13960..16656)
                     /locus_tag="IVV98_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7806355.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="IVV98_000679"
     CDS             complement(17084..18157)
                     /locus_tag="IVV98_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7806356.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="IVV98_000680"
     CDS             complement(18154..18981)
                     /locus_tag="IVV98_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806357.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="IVV98_000681"
     CDS             complement(18982..19788)
                     /locus_tag="IVV98_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806358.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="IVV98_000682"
     CDS             complement(19800..20885)
                     /locus_tag="IVV98_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806359.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="IVV98_000683"
     CDS             complement(20902..21444)
                     /locus_tag="IVV98_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806360.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="IVV98_000684"
     CDS             21702..22691
                     /locus_tag="IVV98_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP7806361.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="IVV98_000685"
     CDS             22688..23425
                     /locus_tag="IVV98_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP7806362.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="IVV98_000686"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="IVV98_000686"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP7806363.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="IVV98_000687"
     CDS             23989..24621
                     /locus_tag="IVV98_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7806364.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="IVV98_000688"
     CDS             24706..25353
                     /locus_tag="IVV98_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7806365.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="IVV98_000689"
     CDS             25358..26341
                     /locus_tag="IVV98_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAP7806366.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="IVV98_000690"
     CDS             complement(26744..28258)
                     /locus_tag="IVV98_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP7806367.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="IVV98_000691"
     CDS             28396..29202
                     /locus_tag="IVV98_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806368.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="IVV98_000692"
     CDS             complement(29377..29946)
                     /locus_tag="IVV98_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806369.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="IVV98_000693"
     CDS             complement(30029..32089)
                     /locus_tag="IVV98_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806370.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="IVV98_000694"
     CDS             complement(32366..33844)
                     /locus_tag="IVV98_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7806371.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IVV98_000695"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IVV98_000695"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP7806372.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="IVV98_000696"
     CDS             complement(35150..36070)
                     /locus_tag="IVV98_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7806373.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="IVV98_000697"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="IVV98_000697"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP7806374.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="IVV98_000698"
     CDS             37799..38332
                     /locus_tag="IVV98_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP7806375.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(38822..39346)
                     /locus_tag="IVV98_000699"
     CDS             complement(38822..39346)
                     /locus_tag="IVV98_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806376.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="IVV98_000700"
     CDS             complement(39339..39812)
                     /gene="tsaE"
                     /locus_tag="IVV98_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP7806377.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(39935..40915)
                     /gene="pta"
                     /locus_tag="IVV98_000701"
     CDS             complement(39935..40915)
                     /gene="pta"
                     /locus_tag="IVV98_000701"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP7806378.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(41068..41748)
                     /locus_tag="IVV98_000702"
     CDS             complement(41068..41748)
                     /locus_tag="IVV98_000702"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP7806379.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            41874..42743
                     /locus_tag="IVV98_000703"
     CDS             41874..42743
                     /locus_tag="IVV98_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7806380.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            42769..43284
                     /locus_tag="IVV98_000704"
     CDS             42769..43284
                     /locus_tag="IVV98_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806381.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(43331..43894)
                     /locus_tag="IVV98_000705"
     CDS             complement(43331..43894)
                     /locus_tag="IVV98_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806382.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(43949..44128)
                     /locus_tag="IVV98_000706"
     CDS             complement(43949..44128)
                     /locus_tag="IVV98_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806383.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(44205..44714)
                     /locus_tag="IVV98_000707"
     CDS             complement(44205..44714)
                     /locus_tag="IVV98_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806384.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(44810..45190)
                     /locus_tag="IVV98_000708"
     CDS             complement(44810..45190)
                     /locus_tag="IVV98_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7806385.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            45520..46269
                     /locus_tag="IVV98_000709"
     CDS             45520..46269
                     /locus_tag="IVV98_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP7806386.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(46453..47730)
                     /locus_tag="IVV98_000710"
     CDS             complement(46453..47730)
                     /locus_tag="IVV98_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806387.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="IVV98_000711"
     CDS             complement(47809..48453)
                     /gene="pcp"
                     /locus_tag="IVV98_000711"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP7806388.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(48652..49596)
                     /locus_tag="IVV98_000712"
     CDS             complement(48652..49596)
                     /locus_tag="IVV98_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP7806389.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(49598..50284)
                     /locus_tag="IVV98_000713"
     CDS             complement(49598..50284)
                     /locus_tag="IVV98_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP7806390.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT        14904 a        10438 c         8611 g        16340 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt taagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatatag gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctgattt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccattttttt
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc aagaggttgt gaaatcagcg ttttgacctg agtattagag
    38641 aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata ccgaaggtca
    38701 gctgattgaa caccgtttat tcaaaaaaaa tggactgcga cacgactttt gtcacagtcc
    38761 cttcgtgtgt ttttctgcct tctcaaaagg atgacagttt ctcactcttt tcctatttct
    38821 tctattcaat caaataactc attttatata catctaaaaa ttcacctaga tctgttcttg
    38881 cccctctagg catgaccgct tcgatttgga agcccatttt tcggtaaagg tgtacggctc
    38941 tttcattacg aacttgaacg tcaagctcca atcgaaaaag tacacccatt tccttcgccc
    39001 aactgatgat ttcttctagc ataagagtgc ctagtcccat tccccaatat tcctgcagaa
    39061 tactgatacc gacttctccc acgtgagaca aacgaaattg actgtctgcc ttgacagatg
    39121 ctgttccaat aatcgtccct tcatagattg caagcagcaa taaattatta ttgctttcgt
    39181 atatataatc caactcttct tctaaggttt ctggtggtaa caggagttct gcttcatcca
    39241 aaactaaaaa ttctgtctcc ttattaactt gtcccatcat caaaagaatg tcttttgcat
    39301 ctcctggcac tgcttcccgc aagatgatcc caacttcttc actcatgatt ttcagcccat
    39361 ttttctagaa ttcgctgttt gaaggtttca ctttgctccc cgtatgagat tagtttcaca
    39421 taccgctttt ctaaatctgt atcacttttt tctaaaatca gttccaaata atcctccggc
    39481 agtgcttctt ctaatagatt tccccattca acaacggaaa gcccatcacc ttcaaaatat
    39541 tcatctaacc ctaaatctgc tccgctagct gctacccgat aaatatccat atgatacaac
    39601 ggaatccgac cttgactata ttctctaata atcgtgtatg tcggactttt gatcatttgc
    39661 gttatcccta atccttgggc aattcctttc gtcaacgttg ttttacccgc acctagatca
    39721 ccagtcaata tcagattgtc acctggcatt gcggaatgac caattgcctc tgcgaattgt
    39781 tctgtcattg ttaatcctga tagttcgatc atttttcatc ttctcccgct cttctttctt
    39841 tttgccagta tatcgcgtaa tgaagttttt ttaaagaaaa aatgaactag tcaagaacag
    39901 cagctgctgt ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg
    39961 tgataatcga taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg
    40021 gtttgttcaa gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa
    40081 ttttatagcc gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag
    40141 ctacttctga atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt
    40201 gcaattcgcc gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa
    40261 ctactttgtc tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta
    40321 cttttggttc gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca
    40381 attcttgcgc agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat
    40441 ctcttccacg taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga
    40501 tgatctgaag tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc
    40561 cgtctgcaat ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct
    40621 tttctgcttg ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt
    40681 catcccactt atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc
    40741 tggcatgcgc tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt
    40801 cttctgcttt caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa
    40861 cgattttgat cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat
    40921 gacctccaga cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta
    40981 ttttatctgt atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact
    41041 gcactataac aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg
    41101 ttcttctcct aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa
    41161 gccacgactt gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt
    41221 atcgatcatt ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt
    41281 ttcccgttca tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg
    41341 atgagaatac gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg
    41401 tttagcccat gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag
    41461 ctctttatag atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga
    41521 taagccatga gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac
    41581 ttcttcataa ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt
    41641 ttgggacgca tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa
    41701 ttctgaggac aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc
    41761 ctaataaaaa gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca
    41821 cttgattaat atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca
    41881 aattaattgc atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg
    41941 aaaatgccga ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg
    42001 gtcgaaacta tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga
    42061 tcactttgaa cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga
    42121 ttccaaataa tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg
    42181 aagtagcaac caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg
    42241 cttccatggt ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct
    42301 cagctaagct ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag
    42361 aaaagaatct ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag
    42421 gtccagttgg aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa
    42481 acaatatcga agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc
    42541 acgagcgtgg gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca
    42601 gcatgctgca agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag
    42661 attatgccaa atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc
    42721 gcgcgattgc agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt
    42781 ttcattcagg aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga
    42841 cattccctgt ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat
    42901 gccatgaatg gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt
    42961 tttgagctgt ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc
    43021 ggtgactttt attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat
    43081 caatatcaaa tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt
    43141 tcaggagatt actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt
    43201 attgctgcgg ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt
    43261 tcttaccgac ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag
    43321 gtacatcttt ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct
    43381 gaccgacaac tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat
    43441 ccacacttag accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta
    43501 ataatcgcga accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat
    43561 accattcgtt gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat
    43621 atttctctaa gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac
    43681 cgtaagcaac tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt
    43741 aacgataatt tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg
    43801 tctgcttcaa aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt
    43861 ctggagcatc ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta
    43921 acatgcagaa aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa
    43981 tgaaataacc atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg
    44041 gcatttcttt atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc
    44101 cgcaattagg gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct
    44161 tagcttactc ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat
    44221 acctgacggt cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg
    44281 actagaagtg tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc
    44341 atcgctgctt gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg
    44401 gccttttccg tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact
    44461 tgtccttcac aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt
    44521 tcaactgcaa aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct
    44581 gctgcttttt tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg
    44641 gcattgagca gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac
    44701 atcatttttt tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa
    44761 cgaatgaaaa atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca
    44821 gttctaatgg caatccgtct ggatcaaaga aaaacgtcat tttttttcct gtaaaggtat
    44881 cttctctaat cggttctgat tcgatcccta aggactgcaa ttctgcaatt gtttcttcaa
    44941 tatcgtctac tttgaaagca agatgacgca agccacaagc ttctggatag tttggtcgtt
    45001 gtggcgcatt agcaattcca aaaatctcca attcagcact tcctagtttc agatctaatt
    45061 tatagtcatc tcgttctttg cggtaatttt ctctgattac ttcaaatcct aatttattaa
    45121 cataaaaatc acgtgatttc tgataatctg aaacaatgat ggctatatga tggatcgttg
    45181 taaggttcat atgagcactc ctattcttcg tttaagctcg gatctatatt aatctccagt
    45241 tccattgtaa atgtgtcaga ttgaaaaaaa tagctgtttt tcctttttat aagaaaaaag
    45301 gcaaaaaaaa cagaaagtag gtcctccaag acactcttcc tgttcccaat ataataaatg
    45361 aaagtaagaa attatatttt caagaaaaca aacagaaaat tatcataaca caaattattt
    45421 ataattgaaa gactagtttt ttttcaagaa aagcatacaa tagattgtgt tagtaaatac
    45481 agaacacact acatttagtg tcttaaggag tcctcataca tgaagtcata ttttcagttt
    45541 ttagctcatc agctaaaagg ctggccgcaa caaaattatt atcttttctt tttcagtctt
    45601 ggctgccagg tcatgactct tgtcaatagt cccatcactt ggctgtccgt tattacattt
    45661 atcggtacca cgcttggtgt attgtgtatt ttatccatca atgcggcaaa atcagtcaac
    45721 ggtattttag gtattttgtc tgcgatttgt tttattatcg ttgggttttc agcaaagaac
    45781 tatttaagta tcggtgaaca gattgcttat atgatcacat tggatatccc cgtattgtta
    45841 agtaaagaat ggaatcataa tatggcttca aaaatccgaa aattcactgg aaaaagctgg
    45901 tttatcgcaa tcatcagtac tttccttgtc tatcttgttt caggattcct gattggtcgt
    45961 tatacagatg atcctcggcc gtgggtagat gccattgctt tttctattag cttgactgct
    46021 ggtatcatca gtttcttgcg ttacaacaac caatattact ggtggttagc ttcagggctt
    46081 gctcaaatgg tcctttggta tatttcattt acgcatggat ctgcaagttt ggcgatgttc
    46141 gtgaacagct ctgtttactt gctgaatgat gtccttgcat ttaccgtttc accttggtat
    46201 aaccaaaaag aacgtgaacg tatgcaaaaa atggaagaag aatactacaa cgcacaacaa
    46261 cacgcataaa aaaactgagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    46321 acacgtataa acggcggaat cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    46381 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
    46441 agcctctatt ttttatagta attccttcag atactttctt gcctcatcat tgaaacgcag
    46501 tgattcttct aacttctgat aatattccaa cgcttgtttc tgagcttcag taaaacgata
    46561 atgttttcct ttccatttgt cgattgtctc ttgcacattt ccagattgga tatctttcac
    46621 tactagttgc catttttctt ttgagactgt acggtctttc ttatcagcag attgtatagc
    46681 ttctcgttct ttacgcaata cttttaaaaa accatttctg actatccgag gaatgctgtc
    46741 gaagaaccct tctgtaaaac catagcgaca atattgcttc caaataaata gatagatttt
    46801 tggttggatg aatcgttggt ttttcgcaaa atattccatc tgagcagtga cttctggtgt
    46861 tcgttgacgt tttgtctttc tcaacacgga aataaatgtt tcaaaataag cattaggatg
    46921 tactggcact tcttcatata cgatggattg ccaatcttta cgtaaaaatg cgcgatagtt
    46981 gatcaagaat tcttctacat cctttactaa ttcttctgca aagtcgtcaa atagttcttt
    47041 ttttatctgt cgcttttttg actgcccatt gatgtgttca cttattttct tgatttcatt
    47101 ttccaatgct tgataatccg ctatgtaaat cggcatttct acttggcgaa attctgcgag
    47161 ccgctgagct aattttatat ccggtaaata tggctgtttc atccgacgat tttggtacaa
    47221 gacaaaacag tatttttgcc atagtccttc aggaaaatcg atattcttct gcttaagcca
    47281 taataattcg tctaaggcca gatcaacttt tgtcattccc tgatggatcg aagctgccac
    47341 tgtcggagag acatgcaggt gatcggcaaa gtggttgatg cctagtttta ggatctttcc
    47401 ggtttttggc gatttaacga tgtattgcac ttttaattct ctaccacact cacaatacaa
    47461 tttttgctgg cttcgttttg ttcgaaaaaa cggattgatc ttgaagtcag aaaacaccca
    47521 atctgttgca gctaaataat gttcttccat aaaacgagag ctgattagat atcggcggtg
    47581 cttatcgact agttcccgct gttttttcgt taattttgca tagatctccc aacgttgact
    47641 gcttgtgtat tgtttagaaa ttttgatggg atagcttttg ctgatttctt ttggaaacca
    47701 ttcttcaaag acggattgcc attcttccac ggctgtttct ttcctttcta attacaaaaa
    47761 gctggctact aacataacgt tagcaaccag ccagtgtttc ttgctaaatt agtgagttgt
    47821 tccggcattt ccggaaatat cttctttatt ttctactgct gcttcaactg cataagtcaa
    47881 agaagaagca atgtcttcta aagacataga aggcgtaccc actggacgat cgatcacttg
    47941 atcgggtgag aatggcacgt ggatgaaccc acctcgaatt gccgggaatt gtgtttcgat
    48001 caaatgaagc aaacgataca tgatatcatt gcagacaaat gttcctgctg tataagagat
    48061 gtacgctggt agaccatgat cttgtacatt ttttgtcatt gctttgattg gcaatgaggt
    48121 aaagtaagcg gctggaccgt tttcttctaa agccgtatcg aatggctgat ttccttcatt
    48181 atcagggatt cttgcttctg ctagattgat tgcgacacgt tcgaacgaga ctgctgaccg
    48241 cccacctgct tgtccgacac agatcacgac atctggttgg tgctgttgga tggcttcttt
    48301 gactacttga ctgctttttt cgaatacggt cggtacttcc actttgatga tttcagcacc
    48361 gctgatttca tctggcattt tttttactgc ttcataggct ggattcactt tgtccccacc
    48421 aaatggatca aaacctgtta ctagtacttt catctgttgt tcctccgtcc gattgattta
    48481 acatatggtt atcttttatc ataccatttt ccttgaacag cgtaaataaa ggaaacaata
    48541 gtttaaataa cataacagat caaacttaat atattcttat aaaaaaatag tgttccacta
    48601 caatgttaga agaggttgcg acaattattc tgtcacaacc cctctcttct attatttaaa
    48661 tagaatcata taagcaattt ggaaaactag cataaataac gcaataaaca actggttttt
    48721 gatcactccg tatttgtctt tcatctccag catcgctaca ggcacgatat tgaagttagc
    48781 agccatcggt gtcagcaggg tcccacaaaa accgcaagtc aatgcaacca ttcctattaa
    48841 cgctggattc gctccatgac taaatacgaa tggtgcaccg atcccaaccg tcatcacggt
    48901 gatggccgca aatgcattcc ccatgattac cgtaaatatc accatgccaa gagcgtaaat
    48961 gatgatgccg atgttcacat ttccttctgg aacgatcgta cctactgcat tggaaatcac
    49021 tgtcccaact ccagcgcttg taaataccgc acctagagaa gctaaaagca ttggcaacat
    49081 gcttaacggc cctactgtgc ccagcatatc tgctgcatca tctaaaaatg tacttggtcg
    49141 attatctcga gaaaagaaca tcaagattag catggctgca aaaacaccga cgcccacgcc
    49201 gactaaagca cctaaattgg taaatagagc aaacaagatc gcaaagacac cgatactcaa
    49261 agctggaata aaaattttca ttcctagttt gtctgacatt ttttccatat attcttttga
    49321 tggaagccgg ctttctcctt tgctgacttt cttagcaatt gctggtatgg tcatcgcaaa
    49381 gatcaagcca ccgttcacga ttgccggaag ccatcttcct cctgcaataa ctacccctaa
    49441 gaccgtccag aaaaaggctg acccataacg atgaggattg gttttatctg ttaaatttct
    49501 tactccagtg taaatcaata cgagtcccat cacgatataa aggatctcca gtaatttatc
    49561 gcctaataaa atatcaggat ttgtaaaaaa gtccatctta ttgccccttt cctggataat
    49621 atttcttcgc taatttcttt tctttaagat agaagtagac acttgccaca actaaagccg
    49681 tgatagccac tggaacttcc actaaagcaa gctgtcccaa tgttacgtca tatcctagat
    49741 ctttcagtgt tgattggact agcaacgccc ctgctcctcc gatgaatagt acttggccaa
    49801 agaaccagca gacattttcc atagctgaag ccataccttt tagttcttct tcatgcttag
    49861 gatggacttc taaccctttt gattcgatgg tccccaatgc catcggtaaa atgattggac
    49921 gaacaaatcc agcaactcca ccaaaactca cgttaaaagc cgcaaagatc attcgaaaga
    49981 tcccataaat atctacaatc ataccagcag atactttctt gaatcgcttg atcaaggaag
    50041 ccgctgattc tttcagacca tttctttcaa gcgttcctgt tgccaacata atgatgataa
    50101 aaatcgccat cccgcgattg tttacaaaac ttgtacctaa aagttctaac attccttgaa
    50161 tgccaagacc gccagtcaaa gctgtaacaa ctaaagcaac cattacgatc aatatcgagt
    50221 ctaatttaaa tgcaaacccg agaataacaa tcaagacgcc taaaaggcta agataatttt
    50281 ccatatattt tcc
//
LOCUS       DACCVH010000011        47456 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.011, whole genome shotgun sequence.
ACCESSION   DACCVH010000011 DACCVH010000000
VERSION     DACCVH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.011"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2387)
                     /gene="esp"
                     /locus_tag="IVV98_000714"
     CDS             complement(<1..2387)
                     /gene="esp"
                     /locus_tag="IVV98_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAP7806391.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
     gene            complement(3004..3438)
                     /locus_tag="IVV98_000715"
     CDS             complement(3004..3438)
                     /locus_tag="IVV98_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806392.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3455..4660)
                     /locus_tag="IVV98_000716"
     CDS             complement(3455..4660)
                     /locus_tag="IVV98_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAP7806393.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5354..5740
                     /locus_tag="IVV98_000717"
     CDS             5354..5740
                     /locus_tag="IVV98_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7806394.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5834..6025
                     /locus_tag="IVV98_000718"
     CDS             5834..6025
                     /locus_tag="IVV98_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806395.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6539..6871
                     /locus_tag="IVV98_000719"
     CDS             6539..6871
                     /locus_tag="IVV98_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7806396.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7167..7322
                     /locus_tag="IVV98_000720"
     CDS             7167..7322
                     /locus_tag="IVV98_000720"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP7806397.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7598..8938
                     /locus_tag="IVV98_000721"
                     /pseudo
     CDS             7598..8938
                     /locus_tag="IVV98_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9179..10795)
                     /locus_tag="IVV98_000722"
     CDS             complement(9179..10795)
                     /locus_tag="IVV98_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP7806398.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10913..11131
                     /locus_tag="IVV98_000723"
     CDS             10913..11131
                     /locus_tag="IVV98_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806399.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11326..11787
                     /locus_tag="IVV98_000724"
     CDS             11326..11787
                     /locus_tag="IVV98_000724"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7806400.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11980..12219)
                     /locus_tag="IVV98_000725"
     CDS             complement(11980..12219)
                     /locus_tag="IVV98_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806401.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12243..13766)
                     /locus_tag="IVV98_000726"
     CDS             complement(12243..13766)
                     /locus_tag="IVV98_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP7806402.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13784..13906)
                     /locus_tag="IVV98_000727"
     CDS             complement(13784..13906)
                     /locus_tag="IVV98_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP7806403.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13936..14919)
                     /locus_tag="IVV98_000728"
     CDS             complement(13936..14919)
                     /locus_tag="IVV98_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP7806404.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14943..15092)
                     /gene="rpmG"
                     /locus_tag="IVV98_000729"
     CDS             complement(14943..15092)
                     /gene="rpmG"
                     /locus_tag="IVV98_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7806405.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15113..15490)
                     /locus_tag="IVV98_000730"
     CDS             complement(15113..15490)
                     /locus_tag="IVV98_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806406.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15522..15701)
                     /gene="rpmF"
                     /locus_tag="IVV98_000731"
     CDS             complement(15522..15701)
                     /gene="rpmF"
                     /locus_tag="IVV98_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP7806407.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15716..15985)
                     /gene="rpsN"
                     /locus_tag="IVV98_000732"
     CDS             complement(15716..15985)
                     /gene="rpsN"
                     /locus_tag="IVV98_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP7806408.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16508..18280)
                     /locus_tag="IVV98_000733"
     CDS             complement(16508..18280)
                     /locus_tag="IVV98_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806409.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18234..19988)
                     /locus_tag="IVV98_000734"
     CDS             complement(18234..19988)
                     /locus_tag="IVV98_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806410.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20098..20667)
                     /locus_tag="IVV98_000735"
     CDS             complement(20098..20667)
                     /locus_tag="IVV98_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAP7806411.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20685..22109)
                     /locus_tag="IVV98_000736"
     CDS             complement(20685..22109)
                     /locus_tag="IVV98_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7806412.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(22111..22779)
                     /locus_tag="IVV98_000737"
     CDS             complement(22111..22779)
                     /locus_tag="IVV98_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP7806413.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22909..23493)
                     /locus_tag="IVV98_000738"
     CDS             complement(22909..23493)
                     /locus_tag="IVV98_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7806414.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23824..24057)
                     /locus_tag="IVV98_000739"
     CDS             complement(23824..24057)
                     /locus_tag="IVV98_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAP7806415.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24072..25022)
                     /locus_tag="IVV98_000740"
     CDS             complement(24072..25022)
                     /locus_tag="IVV98_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP7806416.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(25019..25861)
                     /locus_tag="IVV98_000741"
     CDS             complement(25019..25861)
                     /locus_tag="IVV98_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7806417.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25863..26582)
                     /locus_tag="IVV98_000742"
     CDS             complement(25863..26582)
                     /locus_tag="IVV98_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7806418.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27274..27432
                     /locus_tag="IVV98_000743"
     CDS             27274..27432
                     /locus_tag="IVV98_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806419.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27504..28730
                     /locus_tag="IVV98_000744"
     CDS             27504..28730
                     /locus_tag="IVV98_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7806420.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28818..29210)
                     /gene="rpsI"
                     /locus_tag="IVV98_000745"
     CDS             complement(28818..29210)
                     /gene="rpsI"
                     /locus_tag="IVV98_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP7806421.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29226..29669)
                     /gene="rplM"
                     /locus_tag="IVV98_000746"
     CDS             complement(29226..29669)
                     /gene="rplM"
                     /locus_tag="IVV98_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP7806422.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30188..30655)
                     /locus_tag="IVV98_000747"
     CDS             complement(30188..30655)
                     /locus_tag="IVV98_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP7806423.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30775..32313)
                     /locus_tag="IVV98_000748"
     CDS             complement(30775..32313)
                     /locus_tag="IVV98_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP7806424.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32393..33079
                     /locus_tag="IVV98_000749"
     CDS             32393..33079
                     /locus_tag="IVV98_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP7806425.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33280..33807)
                     /gene="msrA"
                     /locus_tag="IVV98_000750"
     CDS             complement(33280..33807)
                     /gene="msrA"
                     /locus_tag="IVV98_000750"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7806426.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33891..34568)
                     /gene="pgmB"
                     /locus_tag="IVV98_000751"
     CDS             complement(33891..34568)
                     /gene="pgmB"
                     /locus_tag="IVV98_000751"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP7806427.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34565..35695)
                     /locus_tag="IVV98_000752"
     CDS             complement(34565..35695)
                     /locus_tag="IVV98_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7806428.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35695..37878)
                     /locus_tag="IVV98_000753"
     CDS             complement(35695..37878)
                     /locus_tag="IVV98_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP7806429.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37875..38900)
                     /locus_tag="IVV98_000754"
     CDS             complement(37875..38900)
                     /locus_tag="IVV98_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7806430.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38945..39772)
                     /locus_tag="IVV98_000755"
     CDS             complement(38945..39772)
                     /locus_tag="IVV98_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7806431.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39769..40836)
                     /locus_tag="IVV98_000756"
     CDS             complement(39769..40836)
                     /locus_tag="IVV98_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP7806432.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSESNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40862..41698)
                     /locus_tag="IVV98_000757"
     CDS             complement(40862..41698)
                     /locus_tag="IVV98_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7806433.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41695..42564)
                     /locus_tag="IVV98_000758"
     CDS             complement(41695..42564)
                     /locus_tag="IVV98_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806434.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42634..43917)
                     /locus_tag="IVV98_000759"
     CDS             complement(42634..43917)
                     /locus_tag="IVV98_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7806435.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43931..45616)
                     /locus_tag="IVV98_000760"
     CDS             complement(43931..45616)
                     /locus_tag="IVV98_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP7806436.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45891..46916
                     /locus_tag="IVV98_000761"
     CDS             45891..46916
                     /locus_tag="IVV98_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7806437.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT        14675 a         9318 c         7521 g        15942 t
ORIGIN      
        1 aagcttacgc cgtctttcac tgcaaagact gttgttccac tttcaatact tgttccttcc
       61 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
      121 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      181 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      241 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      301 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      361 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      421 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      481 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      541 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      601 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      661 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      721 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      781 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      841 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      901 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      961 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
     1021 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1081 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1141 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1201 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1261 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1321 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1381 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1441 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1501 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1561 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1621 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1681 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1741 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1801 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1861 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1921 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1981 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     2041 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2101 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2161 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2221 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2281 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2341 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2401 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2461 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2521 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2581 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2641 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2701 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2761 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2821 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2881 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2941 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     3001 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3061 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3121 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3181 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3241 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3301 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3361 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3421 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3481 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3541 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3601 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3661 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3721 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3781 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3841 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3901 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3961 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     4021 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4081 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4141 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4201 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4261 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4321 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4381 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4441 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4501 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4561 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4621 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4681 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4741 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4801 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4861 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4921 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4981 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     5041 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5101 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5161 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5221 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5281 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5341 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5401 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5461 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5521 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5581 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5641 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5701 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5761 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5821 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5881 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5941 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     6001 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6061 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6121 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6181 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6241 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6301 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6361 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6421 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6481 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6541 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6601 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6661 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6721 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6781 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6841 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6901 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6961 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     7021 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7081 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7141 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7201 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7261 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7321 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7381 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7441 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7501 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7561 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7621 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7681 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7741 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7801 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7861 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7921 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7981 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     8041 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8101 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8161 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8221 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8281 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8341 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8401 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8461 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8521 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8581 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8641 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8701 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8761 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8821 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8881 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8941 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     9001 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9061 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9121 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9181 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9241 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9301 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9361 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9421 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9481 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9541 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9601 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9661 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9721 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9781 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9841 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9901 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9961 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
    10021 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10081 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10141 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10201 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10261 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10321 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10381 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10441 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10501 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10561 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10621 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10681 catttacaat gacagcaatt ttctttccgt gatcaccgta cagaatatga tttagaagta
    10741 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10801 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10861 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10921 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10981 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    11041 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11101 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11161 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11221 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11281 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11341 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11401 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11461 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11521 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11581 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11641 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11701 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11761 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11821 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11881 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11941 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    12001 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12061 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12121 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12181 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12241 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12301 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12361 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12421 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12481 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12541 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12601 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12661 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12721 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12781 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12841 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12901 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12961 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    13021 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13081 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13141 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13201 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13261 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13321 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13381 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13441 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13501 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13561 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13621 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13681 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13741 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13801 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13861 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13921 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13981 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    14041 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14101 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14161 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14221 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14281 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14341 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14401 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14461 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14521 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14581 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14641 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14701 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14761 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14821 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14881 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14941 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    15001 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15061 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15121 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15181 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15241 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15301 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15361 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15421 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15481 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15541 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15601 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15661 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15721 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15781 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15841 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15901 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15961 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    16021 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16081 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16141 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16201 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16261 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16321 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16381 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16441 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16501 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16561 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16621 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16681 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16741 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16801 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16861 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16921 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16981 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    17041 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17101 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17161 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17221 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17281 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17341 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17401 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17461 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17521 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17581 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17641 attctatagt ttcttgaaat tcttccgagt tctctctcaa agtatcgtaa tatttagtat
    17701 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17761 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17821 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17881 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17941 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    18001 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18061 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18121 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18181 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18241 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18301 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18361 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18421 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18481 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18541 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18601 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18661 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18721 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18781 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18841 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18901 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18961 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    19021 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19081 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19141 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19201 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19261 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19321 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19381 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19441 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19501 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19561 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19621 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19681 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19741 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19801 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19861 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19921 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19981 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    20041 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20101 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20161 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20221 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20281 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20341 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20401 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20461 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20521 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20581 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20641 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20701 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20761 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20821 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20881 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20941 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    21001 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21061 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21121 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21181 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21241 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21301 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21361 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21421 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21481 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21541 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21601 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21661 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21721 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21781 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21841 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21901 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21961 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    22021 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22081 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22141 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22201 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22261 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22321 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22381 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22441 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22501 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22561 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22621 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22681 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22741 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22801 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22861 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22921 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22981 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    23041 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23101 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23161 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23221 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23281 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23341 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23401 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23461 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23521 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23581 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23641 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23701 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23761 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23821 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23881 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23941 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    24001 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24061 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24121 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24181 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24241 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24301 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24361 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24421 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24481 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24541 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24601 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24661 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24721 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24781 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24841 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24901 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24961 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    25021 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25081 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25141 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25201 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25261 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25321 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25381 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25441 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25501 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25561 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25621 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25681 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25741 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25801 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25861 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25921 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25981 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    26041 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26101 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26161 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26221 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26281 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26341 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26401 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26461 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26521 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26581 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26641 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26701 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26761 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26821 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26881 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26941 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    27001 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27061 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27121 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27181 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27241 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27301 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27361 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacattt
    27421 aaaataactt gaaattttct tctcgccgca tatactaaaa ttagtgaaat atactgcctt
    27481 acttttttta aggagtgagg attttgccta caaagctttc aaatgggaaa tataaaacta
    27541 atctgagata tccaaaaagg tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa
    27601 aaacatttcc aaataggcaa ttggcgatta aagccgaaaa tgatatgaag aagaaaatag
    27661 aaaaagtttt gagagaggag aatgcaaact cattagaatt aaaaggaaaa ataacgttta
    27721 aaaaatttta cgaatctaaa tggcttccta gatatgaatt aggtcaaaca attagatcaa
    27781 acaggcctcc tagtgatata accattagta atacaaaaga tatatttcgg ttgcatattt
    27841 tacctatgtt tggtgaatac gcaatgaatt atctaaatat caatactgag ataatatcag
    27901 atgaattaac caaaaaatcg aaagaatatg caaatataaa aatcataaaa ggatatgttc
    27961 gttccatgtt cgatattgca gaaatactaa attatatcga atttaatcga actactaaaa
    28021 ttattcaaag tatcactgca cctaaaaaaa atgctttaga agaaaaaaga atacaagaag
    28081 gtaagcaagc actatcatca aaagaactta ctaattggat agaagcagta aatgatgatt
    28141 ttaataatca tttacttact tttcatgatt acacactttt tatgattacc ctgtatcttg
    28201 gtgatagaaa aagtgagact tacgctttgc aatggaaata tattgatttt gaaaaacaaa
    28261 cggtccgtct taaacatact ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa
    28321 aagataccgt cattcaagta ccagaagttg taatgacatt gctaagtgaa tggaaatcgg
    28381 tacaagctga tcaattgttg aaattaaaaa ttaagcaaac gttagatcag tatctcttta
    28441 cttatactaa accatctgga gaagtaaatt gtcctgttca tgccgattac ctaaactatc
    28501 gaatcaattc aattaaaaga aggcatcctg acttagttca tttatctcca cacaaactcc
    28561 gtcatactta tgcaactata gctagacaag gtggagcaga tatgaatcaa atttcaaatg
    28621 ctttaacaca ctcagatatt tctacaacaa agatatatgt gaacacacca gatatagttg
    28681 ataaggctgt ttttgaagct tttcagagag gattgaataa gtgtgattga tatgtgttct
    28741 taaatgtgtt cttaaaaaca aaagaagcac tttccaaata attgaaaagt gccagaaacg
    28801 ttgatatata aaggatatta acgttttgag aattgtgaag ctttacgtgc tttcttaaga
    28861 cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc acgtttaaga
    28921 gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg acggatagct
    28981 cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata tgcgcctttt
    29041 gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg tggaatgtat
    29101 tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag acgtacgcga
    29161 gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa tgaaattccc
    29221 tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc atgtggatgt
    29281 tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt gtttttagga
    29341 agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg caattcgcca
    29401 gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc
    29461 gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa atcgccagta
    29521 tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc aacaactgtt
    29581 gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg ttctacttcg
    29641 cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag ttctgatgtt
    29701 tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat ttaacatatt
    29761 acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt atatgaaact
    29821 ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa
    29881 gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg ttctcctgcc
    29941 aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt ttaaaattgt
    30001 ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg tgttcaatca
    30061 gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt tgacgtttgt
    30121 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc aagttcaaca
    30181 acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc atccagatac
    30241 gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg tcgccttctt
    30301 ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag cctgcaacaa
    30361 gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca gggatttttg
    30421 tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt
    30481 cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc attgggtgca
    30541 atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca acagacattt
    30601 ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat ttcatctttc
    30661 ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga aaagtacaac
    30721 aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag ccaatcattt
    30781 ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct gtgctaaatg
    30841 cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat cagtttcttg
    30901 tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac tttggatctt
    30961 tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg tgacagtagg
    31021 gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg gagattgagc
    31081 aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc cttttaaaat
    31141 ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt tttctgtatg
    31201 ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc
    31261 accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa aagcgatagc
    31321 cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa cgacttcctg
    31381 taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg ctcctcccac
    31441 tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat ggaactgagg
    31501 ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc
    31561 accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca aaacaaatga
    31621 tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg ttacttgata
    31681 ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt caagcacttc
    31741 ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg ttccgtagtc
    31801 gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga caaaataagc
    31861 agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt tcaatggtgt
    31921 cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca cggtatattt
    31981 cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc gagataacgg
    32041 tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg agacaaattg
    32101 aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc agacaccttg
    32161 aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca aagggtagcg
    32221 aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt
    32281 ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt tatgtatgta
    32341 caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg gcgtgttact
    32401 ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc agcggattcc
    32461 gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc gttcgctttc
    32521 ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct gccgctattg
    32581 caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg gtctttttgc
    32641 ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc
    32701 tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca cgctattctg
    32761 ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt
    32821 gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc
    32881 tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag agttgcttca
    32941 gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact ttatctgtca
    33001 taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt tgctgattgt
    33061 ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac ctctgatata
    33121 tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca caacctctcc
    33181 actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg ttttacaacc
    33241 tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga cgccccaatg
    33301 tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat ggagcttgtt
    33361 tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc ttggttcgat
    33421 ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc
    33481 tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag aatcaccgcg
    33541 atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga tttccaccaa
    33601 ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg tatgccctgt
    33661 tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag tataaccgga
    33721 tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc aaaagcatcc
    33781 gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat cataccttga
    33841 tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta ttatatacgt
    33901 gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt taaatcagga
    33961 atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac atgcatgtta
    34021 ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca tgcatttggc
    34081 ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt tgcttttgat
    34141 acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt ttctaaaatg
    34201 aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt tttcaagtac
    34261 tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg aatcgcttga
    34321 agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga gaatttctgt
    34381 tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat tcctttcagt
    34441 tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac cagccacgct
    34501 tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag tgctgctttg
    34561 attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg atgtttttag
    34621 ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag
    34681 gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt cctttaccaa
    34741 cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca atcccaactg
    34801 gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt acgaggtctg
    34861 cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg ccagagacta
    34921 ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca ctactgcccg
    34981 atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct tggtcagcca
    35041 ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa gcgccttctt
    35101 ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta atcagctcaa
    35161 taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc agtgcttcta
    35221 ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg ccgatgccgc
    35281 catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca
    35341 attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt tgttggttta
    35401 gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg
    35461 aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct gtttgccgct
    35521 tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg cctataggta
    35581 gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg
    35641 cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata cgcattattt
    35701 tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat tgacaaaaat
    35761 aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca aaacaaatag
    35821 caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg aaggaagtct
    35881 tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa atataactgc
    35941 tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat gcggatctgg
    36001 tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca tttcttggat
    36061 acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt
    36121 ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag gtaataagta
    36181 taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt cgctacgggc
    36241 ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca aatcaataac
    36301 tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag gcactggcaa
    36361 atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc cagcttgata
    36421 tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat tattgtcgat
    36481 atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat catcgacttt
    36541 tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc cctttgtttc
    36601 taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag caaggtctgc
    36661 actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg ttttgatatt
    36721 caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc atgggaaaag
    36781 tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg
    36841 gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag gcaggataaa
    36901 aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc ccttcgcccc
    36961 tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag cagcgaagtc
    37021 catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa
    37081 atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc ttttctgggc
    37141 ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga gcacgatgat
    37201 cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag cggtgatccg
    37261 gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc caatatcaat
    37321 tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata ctcgcagttc
    37381 tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac ccgttttcac
    37441 atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg cctgatggag
    37501 attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt gagcagtttc
    37561 aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct cgtatgcaag
    37621 aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc atctgatgac
    37681 atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat atacaccagc
    37741 tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc tgataccaaa
    37801 aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta aatcaaactg
    37861 tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg atataaattt
    37921 tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg agtctggtca
    37981 ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt aactggcgtg
    38041 gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc tggatacaga
    38101 ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct gatattcaaa
    38161 gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt gccaaaaatt
    38221 gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga attttttttc
    38281 gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa tccagtaata
    38341 tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc tccttgaagt
    38401 tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc attcgcttct
    38461 acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc ttcgtcagaa
    38521 aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt ctctgccatc
    38581 tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga agcattagct
    38641 tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac actcacgata
    38701 tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga aaatcctgta
    38761 cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc caattctaag
    38821 acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg tccagcgcct
    38881 atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta ttgttattct
    38941 ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag tttttcaagt
    39001 attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga cattcatata
    39061 ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta aaatcaattg
    39121 cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc acatactctt
    39181 tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga taaaaatcag
    39241 cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca tccgctaaca
    39301 aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc gtacctgttt
    39361 cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag tctccttctt
    39421 tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa gctgctggga
    39481 taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca atttgacgta
    39541 caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag ccgttacaag
    39601 ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg atattttcta
    39661 ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata aatctaaatt
    39721 tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc attgttctcc
    39781 tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta cataacgcat
    39841 gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt cacaatccaa
    39901 gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt tccatcttgg
    39961 gtaatctggg tttgattcac tagatgctcg agcaaagacg atttttgcat tattgaaatg
    40021 tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa cataagaaat
    40081 gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac tgccactcgt
    40141 ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa aaccgacatc
    40201 tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt ctctacgctg
    40261 cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta attgaatcgc
    40321 aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc gaacatgtgc
    40381 ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat ttttccattg
    40441 atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa tcagcgtttc
    40501 acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca ccaaactgcc
    40561 cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa ataccacacc
    40621 gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa attcttcatc
    40681 gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg gagtagcgaa
    40741 aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc
    40801 ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct ttcttttctt
    40861 tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca gataacgcat
    40921 acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt ccccaaatgt
    40981 agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg
    41041 acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa taaacgaaga
    41101 cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc tggatccggc
    41161 taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt
    41221 ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc agtgctgtat
    41281 tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg atcaaaatac
    41341 cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct ttgaagcgta
    41401 gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg gaggctatca
    41461 aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa
    41521 tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc gttgcaattg
    41581 cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac aaattgacag
    41641 ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta tttttcattt
    41701 caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga acaatagaat
    41761 cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat acaaataaac
    41821 gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat agaacatcca
    41881 gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca gtgtcacgat
    41941 cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa gcgttttgtc
    42001 gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc tccagatagc
    42061 aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg gtgcttcgtt
    42121 gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat tattgaacat
    42181 atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata aaatcagtga
    42241 acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa
    42301 agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta aagaacgata
    42361 aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa cggcgtctga
    42421 gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca ttggaatcag
    42481 cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta attttaagtc
    42541 agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca atagctatct
    42601 acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt gtgcgtcagc
    42661 taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt ttccgatcac
    42721 acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta gtccaaagac
    42781 ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag acttgatgac
    42841 ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt gagcaccacc
    42901 aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag ctgtgaatgc
    42961 ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc cagatactgt
    43021 gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc
    43081 cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg ctgttccatt
    43141 catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt attgggataa
    43201 gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta cctcgccttc
    43261 atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt gctcactcat
    43321 tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat ctgtgaaatg
    43381 ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag cttctgataa
    43441 tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag caatatagct
    43501 ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat cttctccagc
    43561 ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat ccatcacttt
    43621 agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag ctaacgtaac
    43681 gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga tgtctggatt
    43741 ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct gttcgacaga
    43801 agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac tttcaccaca
    43861 agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt ttttcatttt
    43921 tttccacctc ttattttatt attttcagcc acatatattc atacggctgg aatatcaact
    43981 ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa tctccttttg
    44041 gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact ttctcttcct
    44101 tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa atcaaactat
    44161 tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat tcaccatata
    44221 ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac aaaaattttt
    44281 gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca tttcgacttc
    44341 ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa aatgaatgag
    44401 cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt aacgcatcta
    44461 gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc ttgtagttta
    44521 ctcgggtacc ctctttcttc agctgttcca ctaattcaag gatcgttttt tccggcagaa
    44581 tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta aaaaaagttg
    44641 tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt gtattacccg
    44701 aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc tgtgcttcat
    44761 tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc tcagtgatca
    44821 ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg attttatgcg
    44881 tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc acagcgtcca
    44941 agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc attttcaata
    45001 aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt
    45061 gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag
    45121 tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg tacgtatcat
    45181 tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg cagacaaagt
    45241 cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg cccaaacggt
    45301 cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat gggaaaaatg
    45361 gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat ttcttaaatg
    45421 tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc aagaaaatat
    45481 cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa acactgactt
    45541 tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa atcgcttgta
    45601 aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa cgatttgatc
    45661 atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga tatacacaaa
    45721 aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa atatggtctc
    45781 tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag aatgtctatt
    45841 gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa ttgaaaccta
    45901 ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc agagtattaa
    45961 ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca atcaaagaat
    46021 tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt gacgcgattc
    46081 tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt tcagatgtta
    46141 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    46201 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    46261 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    46321 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    46381 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    46441 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    46501 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    46561 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    46621 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    46681 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    46741 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    46801 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    46861 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    46921 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    46981 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    47041 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    47101 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    47161 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    47221 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    47281 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    47341 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    47401 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagac
//
LOCUS       DACCVH010000012        44868 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.012, whole genome shotgun sequence.
ACCESSION   DACCVH010000012 DACCVH010000000
VERSION     DACCVH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.012"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(2..1012)
                     /locus_tag="IVV98_000762"
     CDS             complement(2..1012)
                     /locus_tag="IVV98_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7806438.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1192..1536)
                     /locus_tag="IVV98_000763"
     CDS             complement(1192..1536)
                     /locus_tag="IVV98_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP7806439.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1529..1963)
                     /locus_tag="IVV98_000764"
     CDS             complement(1529..1963)
                     /locus_tag="IVV98_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP7806440.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2101..2838
                     /locus_tag="IVV98_000765"
     CDS             2101..2838
                     /locus_tag="IVV98_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806441.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2831..4042
                     /locus_tag="IVV98_000766"
     CDS             2831..4042
                     /locus_tag="IVV98_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806442.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4249..5028
                     /locus_tag="IVV98_000767"
     CDS             4249..5028
                     /locus_tag="IVV98_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP7806443.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5098..5760
                     /gene="trmB"
                     /locus_tag="IVV98_000768"
     CDS             5098..5760
                     /gene="trmB"
                     /locus_tag="IVV98_000768"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP7806444.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5858..7612)
                     /gene="ade"
                     /locus_tag="IVV98_000769"
     CDS             complement(5858..7612)
                     /gene="ade"
                     /locus_tag="IVV98_000769"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP7806445.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7744..8673
                     /gene="cpaF"
                     /locus_tag="IVV98_000770"
     CDS             7744..8673
                     /gene="cpaF"
                     /locus_tag="IVV98_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP7806446.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8630..9679
                     /locus_tag="IVV98_000771"
     CDS             8630..9679
                     /locus_tag="IVV98_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP7806447.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9676..9954
                     /locus_tag="IVV98_000772"
     CDS             9676..9954
                     /locus_tag="IVV98_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP7806448.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9929..10399
                     /locus_tag="IVV98_000773"
     CDS             9929..10399
                     /locus_tag="IVV98_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP7806449.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10416..10718
                     /locus_tag="IVV98_000774"
     CDS             10416..10718
                     /locus_tag="IVV98_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806450.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10735..11106
                     /locus_tag="IVV98_000775"
     CDS             10735..11106
                     /locus_tag="IVV98_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP7806451.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11078..11437
                     /locus_tag="IVV98_000776"
     CDS             11078..11437
                     /locus_tag="IVV98_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806452.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11609..12616
                     /locus_tag="IVV98_000777"
     CDS             11609..12616
                     /locus_tag="IVV98_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7806453.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12641..13825
                     /locus_tag="IVV98_000778"
     CDS             12641..13825
                     /locus_tag="IVV98_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP7806454.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14262..15845)
                     /locus_tag="IVV98_000779"
     CDS             complement(14262..15845)
                     /locus_tag="IVV98_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7806455.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16423..16566)
                     /locus_tag="IVV98_000780"
     CDS             complement(16423..16566)
                     /locus_tag="IVV98_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP7806456.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16789..17268)
                     /locus_tag="IVV98_000781"
     CDS             complement(16789..17268)
                     /locus_tag="IVV98_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7806457.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17341..17625)
                     /locus_tag="IVV98_000782"
     CDS             complement(17341..17625)
                     /locus_tag="IVV98_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806458.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17703..17897)
                     /gene="ssrS"
                     /locus_tag="IVV98_000783"
     ncRNA           complement(17703..17897)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IVV98_000783"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17969..19255)
                     /locus_tag="IVV98_000784"
     CDS             complement(17969..19255)
                     /locus_tag="IVV98_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP7806459.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19393..20064
                     /locus_tag="IVV98_000785"
     CDS             19393..20064
                     /locus_tag="IVV98_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP7806460.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20030..20518
                     /locus_tag="IVV98_000786"
     CDS             20030..20518
                     /locus_tag="IVV98_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP7806461.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20531..21478
                     /gene="prmA"
                     /locus_tag="IVV98_000787"
     CDS             20531..21478
                     /gene="prmA"
                     /locus_tag="IVV98_000787"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP7806462.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21479..22243
                     /locus_tag="IVV98_000788"
     CDS             21479..22243
                     /locus_tag="IVV98_000788"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP7806463.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22476..24689
                     /locus_tag="IVV98_000789"
     CDS             22476..24689
                     /locus_tag="IVV98_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP7806464.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24700..25146
                     /locus_tag="IVV98_000790"
     CDS             24700..25146
                     /locus_tag="IVV98_000790"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP7806465.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25317..26576
                     /locus_tag="IVV98_000791"
     CDS             25317..26576
                     /locus_tag="IVV98_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP7806466.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26665..27612)
                     /locus_tag="IVV98_000792"
     CDS             complement(26665..27612)
                     /locus_tag="IVV98_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP7806467.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28006..29298
                     /locus_tag="IVV98_000793"
     CDS             28006..29298
                     /locus_tag="IVV98_000793"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP7806468.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29313..31082
                     /gene="aspS"
                     /locus_tag="IVV98_000794"
     CDS             29313..31082
                     /gene="aspS"
                     /locus_tag="IVV98_000794"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP7806469.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31191..32066
                     /locus_tag="IVV98_000795"
     CDS             31191..32066
                     /locus_tag="IVV98_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7806470.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32332..34215
                     /locus_tag="IVV98_000796"
     CDS             32332..34215
                     /locus_tag="IVV98_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP7806471.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34290..34574)
                     /locus_tag="IVV98_000797"
     CDS             complement(34290..34574)
                     /locus_tag="IVV98_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP7806472.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34564..35298)
                     /locus_tag="IVV98_000798"
     CDS             complement(34564..35298)
                     /locus_tag="IVV98_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP7806473.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35427..36050
                     /locus_tag="IVV98_000799"
     CDS             35427..36050
                     /locus_tag="IVV98_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP7806474.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36242..37363
                     /locus_tag="IVV98_000800"
     CDS             36242..37363
                     /locus_tag="IVV98_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP7806475.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37370..40498
                     /locus_tag="IVV98_000801"
     CDS             37370..40498
                     /locus_tag="IVV98_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP7806476.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40517..43711
                     /locus_tag="IVV98_000802"
     CDS             40517..43711
                     /locus_tag="IVV98_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7806477.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43857..44564)
                     /locus_tag="IVV98_000803"
     CDS             complement(43857..44564)
                     /locus_tag="IVV98_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP7806478.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14401 a         7967 c         9407 g        13093 t
ORIGIN      
        1 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
       61 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
      121 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
      181 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
      241 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
      301 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
      361 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
      421 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
      481 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
      541 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
      601 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
      661 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
      721 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
      781 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
      841 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
      901 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
      961 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     1021 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     1081 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     1141 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     1201 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     1261 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     1321 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     1381 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     1441 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     1501 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     1561 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     1621 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     1681 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     1741 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     1801 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     1861 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     1921 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     1981 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     2041 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     2101 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     2161 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     2221 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     2281 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     2341 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     2401 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     2461 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     2521 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     2581 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     2641 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     2701 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     2761 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     2821 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     2881 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     2941 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     3001 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     3061 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     3121 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     3181 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     3241 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     3301 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     3361 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     3421 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     3481 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     3541 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     3601 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     3661 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     3721 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     3781 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     3841 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     3901 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     3961 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     4021 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     4081 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     4141 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     4201 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
     4261 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
     4321 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
     4381 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
     4441 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
     4501 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
     4561 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
     4621 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
     4681 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
     4741 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
     4801 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
     4861 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
     4921 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
     4981 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
     5041 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
     5101 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
     5161 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
     5221 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
     5281 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
     5341 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
     5401 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
     5461 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
     5521 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
     5581 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
     5641 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
     5701 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
     5761 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
     5821 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
     5881 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
     5941 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
     6001 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
     6061 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
     6121 gctgattgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
     6181 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
     6241 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
     6301 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
     6361 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
     6421 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
     6481 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
     6541 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
     6601 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
     6661 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
     6721 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
     6781 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
     6841 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
     6901 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
     6961 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
     7021 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
     7081 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
     7141 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
     7201 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
     7261 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
     7321 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
     7381 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
     7441 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
     7501 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
     7561 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
     7621 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
     7681 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
     7741 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
     7801 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
     7861 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
     7921 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
     7981 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
     8041 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
     8101 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
     8161 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
     8221 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
     8281 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
     8341 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
     8401 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
     8461 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
     8521 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
     8581 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
     8641 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
     8701 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
     8761 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
     8821 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
     8881 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
     8941 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
     9001 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
     9061 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
     9121 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
     9181 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
     9241 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
     9301 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
     9361 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
     9421 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
     9481 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
     9541 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
     9601 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
     9661 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
     9721 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
     9781 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
     9841 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
     9901 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
     9961 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    10021 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    10081 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    10141 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    10201 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    10261 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    10321 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    10381 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    10441 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    10501 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    10561 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    10621 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    10681 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    10741 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    10801 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    10861 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    10921 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    10981 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    11041 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    11101 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    11161 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    11221 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    11281 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    11341 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    11401 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    11461 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    11521 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    11581 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    11641 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    11701 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    11761 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    11821 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    11881 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    11941 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    12001 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    12061 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    12121 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    12181 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    12241 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    12301 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    12361 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    12421 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    12481 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    12541 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    12601 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    12661 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    12721 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    12781 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    12841 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    12901 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    12961 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    13021 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    13081 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    13141 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    13201 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    13261 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    13321 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    13381 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    13441 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    13501 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    13561 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    13621 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    13681 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    13741 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    13801 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    13861 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    13921 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    13981 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    14041 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    14101 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    14161 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    14221 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    14281 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    14341 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    14401 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    14461 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    14521 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    14581 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    14641 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    14701 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    14761 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    14821 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    14881 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    14941 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    15001 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    15061 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    15121 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    15181 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    15241 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    15301 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    15361 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    15421 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    15481 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    15541 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    15601 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    15661 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    15721 gatttgccag ttccgttgat accgactaag acaatttttt caccagcttc aatttgacag
    15781 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    15841 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    15901 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    15961 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    16021 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    16081 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    16141 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    16201 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    16261 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    16321 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    16381 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    16441 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    16501 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    16561 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    16621 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    16681 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    16741 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    16801 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    16861 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    16921 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    16981 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    17041 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    17101 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    17161 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    17221 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    17281 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    17341 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    17401 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    17461 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    17521 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    17581 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    17641 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    17701 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    17761 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    17821 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    17881 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    17941 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    18001 ttatacggta atactgttga cccagagcct gttcatattt ccctgtatct tttggctgat
    18061 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    18121 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    18181 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    18241 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    18301 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    18361 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    18421 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    18481 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    18541 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    18601 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    18661 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    18721 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    18781 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    18841 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    18901 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    18961 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    19021 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    19081 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    19141 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    19201 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    19261 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    19321 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    19381 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    19441 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    19501 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    19561 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    19621 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    19681 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    19741 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    19801 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    19861 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    19921 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    19981 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    20041 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    20101 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    20161 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    20221 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    20281 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    20341 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    20401 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    20461 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    20521 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    20581 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    20641 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    20701 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    20761 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    20821 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    20881 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    20941 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    21001 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    21061 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    21121 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    21181 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    21241 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    21301 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    21361 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    21421 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    21481 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    21541 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    21601 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    21661 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    21721 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    21781 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    21841 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    21901 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    21961 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    22021 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    22081 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    22141 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    22201 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    22261 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    22321 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    22381 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    22441 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    22501 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    22561 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    22621 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    22681 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    22741 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    22801 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    22861 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    22921 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    22981 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    23041 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    23101 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    23161 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    23221 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    23281 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    23341 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    23401 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    23461 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    23521 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    23581 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    23641 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    23701 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    23761 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    23821 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    23881 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    23941 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    24001 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    24061 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    24121 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    24181 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    24241 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    24301 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    24361 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    24421 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    24481 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    24541 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    24601 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    24661 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    24721 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    24781 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    24841 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    24901 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    24961 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    25021 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    25081 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    25141 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    25201 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    25261 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    25321 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    25381 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    25441 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    25501 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    25561 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    25621 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    25681 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    25741 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    25801 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    25861 taaaaggtgt cgaaaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    25921 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    25981 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    26041 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    26101 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    26161 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    26221 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    26281 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    26341 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    26401 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    26461 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    26521 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    26581 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    26641 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    26701 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    26761 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    26821 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    26881 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    26941 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    27001 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    27061 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    27121 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    27181 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    27241 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    27301 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    27361 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    27421 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    27481 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    27541 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    27601 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    27661 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    27721 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    27781 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    27841 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    27901 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    27961 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    28021 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    28081 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    28141 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    28201 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    28261 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    28321 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    28381 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    28441 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    28501 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    28561 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    28621 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    28681 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    28741 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    28801 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    28861 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    28921 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    28981 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    29041 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    29101 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    29161 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    29221 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    29281 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    29341 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    29401 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    29461 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    29521 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    29581 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    29641 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    29701 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    29761 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    29821 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    29881 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    29941 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    30001 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    30061 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    30121 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    30181 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    30241 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    30301 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    30361 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    30421 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    30481 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    30541 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    30601 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    30661 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    30721 tctatgcaga agcttatgat atcgtcttga acggttatga actaggcgga ggttctatcc
    30781 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    30841 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    30901 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    30961 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    31021 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    31081 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    31141 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    31201 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    31261 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    31321 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    31381 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    31441 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    31501 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    31561 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    31621 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    31681 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    31741 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    31801 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    31861 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    31921 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    31981 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    32041 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    32101 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    32161 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    32221 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    32281 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    32341 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    32401 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    32461 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    32521 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    32581 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    32641 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    32701 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    32761 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    32821 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    32881 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    32941 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    33001 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    33061 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    33121 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    33181 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    33241 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    33301 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    33361 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    33421 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    33481 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    33541 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    33601 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    33661 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    33721 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    33781 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    33841 aaattaaagg aacaagattt gttgaaagac actgttctga tcggactagg aacgaatggc
    33901 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    33961 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    34021 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    34081 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    34141 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    34201 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    34261 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    34321 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    34381 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    34441 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    34501 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    34561 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    34621 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    34681 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    34741 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    34801 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    34861 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    34921 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    34981 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    35041 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    35101 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    35161 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    35221 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    35281 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    35341 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    35401 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    35461 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    35521 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    35581 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    35641 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    35701 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    35761 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    35821 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    35881 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    35941 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    36001 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    36061 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    36121 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    36181 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    36241 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    36301 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    36361 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    36421 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    36481 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    36541 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    36601 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    36661 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    36721 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    36781 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    36841 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    36901 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    36961 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    37021 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    37081 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    37141 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    37201 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    37261 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    37321 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    37381 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    37441 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    37501 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    37561 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    37621 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    37681 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    37741 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    37801 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    37861 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    37921 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    37981 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    38041 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    38101 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    38161 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    38221 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    38281 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    38341 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    38401 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    38461 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    38521 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    38581 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    38641 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    38701 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    38761 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    38821 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    38881 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    38941 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    39001 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    39061 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    39121 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    39181 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    39241 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    39301 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    39361 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    39421 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    39481 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    39541 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    39601 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    39661 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    39721 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    39781 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    39841 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    39901 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    39961 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    40021 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    40081 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    40141 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    40201 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    40261 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    40321 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    40381 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    40441 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    40501 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    40561 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    40621 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    40681 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    40741 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    40801 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    40861 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    40921 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    40981 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    41041 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    41101 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    41161 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    41221 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    41281 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    41341 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    41401 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    41461 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    41521 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    41581 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    41641 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    41701 tggcgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    41761 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    41821 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    41881 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    41941 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    42001 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    42061 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    42121 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    42181 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    42241 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    42301 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    42361 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    42421 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    42481 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    42541 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    42601 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    42661 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    42721 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    42781 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    42841 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    42901 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    42961 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    43021 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    43081 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    43141 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    43201 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    43261 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    43321 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    43381 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    43441 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    43501 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    43561 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    43621 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    43681 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    43741 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    43801 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    43861 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    43921 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    43981 ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    44041 agcatatgaa attctttctc agctagctga aaaatctctt tttctggttt ttggaaacct
    44101 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    44161 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    44221 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    44281 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    44341 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    44401 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    44461 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    44521 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    44581 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    44641 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    44701 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    44761 taatcattat ggtagaagtc gattgattta ttttaatgca atctctgtgg aattttcgaa
    44821 agatttattt ttttaataca gtctcaatat aactattcaa acataaaa
//
LOCUS       DACCVH010000013        44177 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.013, whole genome shotgun sequence.
ACCESSION   DACCVH010000013 DACCVH010000000
VERSION     DACCVH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.013"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            141..4499
                     /locus_tag="IVV98_000804"
     CDS             141..4499
                     /locus_tag="IVV98_000804"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP7806479.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            4644..5117
                     /gene="rimP"
                     /locus_tag="IVV98_000805"
     CDS             4644..5117
                     /gene="rimP"
                     /locus_tag="IVV98_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP7806480.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            5140..6315
                     /gene="nusA"
                     /locus_tag="IVV98_000806"
     CDS             5140..6315
                     /gene="nusA"
                     /locus_tag="IVV98_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP7806481.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            6337..6630
                     /locus_tag="IVV98_000807"
     CDS             6337..6630
                     /locus_tag="IVV98_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP7806482.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            6627..6938
                     /locus_tag="IVV98_000808"
     CDS             6627..6938
                     /locus_tag="IVV98_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP7806483.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            6951..9257
                     /gene="infB"
                     /locus_tag="IVV98_000809"
     CDS             6951..9257
                     /gene="infB"
                     /locus_tag="IVV98_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP7806484.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            9284..9631
                     /gene="rbfA"
                     /locus_tag="IVV98_000810"
     CDS             9284..9631
                     /gene="rbfA"
                     /locus_tag="IVV98_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP7806485.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(9788..9961)
                     /locus_tag="IVV98_000811"
     CDS             complement(9788..9961)
                     /locus_tag="IVV98_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806486.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            10409..12771
                     /locus_tag="IVV98_000812"
                     /pseudo
     CDS             10409..12771
                     /locus_tag="IVV98_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            13139..14062
                     /gene="truB"
                     /locus_tag="IVV98_000813"
     CDS             13139..14062
                     /gene="truB"
                     /locus_tag="IVV98_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP7806487.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            14066..15007
                     /gene="ribF"
                     /locus_tag="IVV98_000814"
     CDS             14066..15007
                     /gene="ribF"
                     /locus_tag="IVV98_000814"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP7806488.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            15359..16144
                     /locus_tag="IVV98_000815"
     CDS             15359..16144
                     /locus_tag="IVV98_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7806489.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            16157..17008
                     /locus_tag="IVV98_000816"
     CDS             16157..17008
                     /locus_tag="IVV98_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP7806490.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(17132..17584)
                     /locus_tag="IVV98_000817"
     CDS             complement(17132..17584)
                     /locus_tag="IVV98_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806491.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(18049..18417)
                     /locus_tag="IVV98_000818"
     CDS             complement(18049..18417)
                     /locus_tag="IVV98_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP7806492.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            18567..19049
                     /locus_tag="IVV98_000819"
     CDS             18567..19049
                     /locus_tag="IVV98_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP7806493.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            19086..20096
                     /locus_tag="IVV98_000820"
     CDS             19086..20096
                     /locus_tag="IVV98_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP7806494.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(20211..20924)
                     /locus_tag="IVV98_000821"
     CDS             complement(20211..20924)
                     /locus_tag="IVV98_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806495.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(21114..21704)
                     /locus_tag="IVV98_000822"
     CDS             complement(21114..21704)
                     /locus_tag="IVV98_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP7806496.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            22188..22415
                     /locus_tag="IVV98_000823"
     CDS             22188..22415
                     /locus_tag="IVV98_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP7806497.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            22431..23597
                     /locus_tag="IVV98_000824"
     CDS             22431..23597
                     /locus_tag="IVV98_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP7806498.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            23831..24874
                     /gene="hrcA"
                     /locus_tag="IVV98_000825"
     CDS             23831..24874
                     /gene="hrcA"
                     /locus_tag="IVV98_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP7806499.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            24968..25531
                     /gene="grpE"
                     /locus_tag="IVV98_000826"
     CDS             24968..25531
                     /gene="grpE"
                     /locus_tag="IVV98_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP7806500.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            25582..27411
                     /gene="dnaK"
                     /locus_tag="IVV98_000827"
     CDS             25582..27411
                     /gene="dnaK"
                     /locus_tag="IVV98_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP7806501.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            27562..28728
                     /gene="dnaJ"
                     /locus_tag="IVV98_000828"
     CDS             27562..28728
                     /gene="dnaJ"
                     /locus_tag="IVV98_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP7806502.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(28810..29475)
                     /locus_tag="IVV98_000829"
     CDS             complement(28810..29475)
                     /locus_tag="IVV98_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAP7806503.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            29451..29624
                     /locus_tag="IVV98_000830"
     CDS             29451..29624
                     /locus_tag="IVV98_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7806504.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(29669..30406)
                     /locus_tag="IVV98_000831"
     CDS             complement(29669..30406)
                     /locus_tag="IVV98_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7806505.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(30408..31910)
                     /locus_tag="IVV98_000832"
     CDS             complement(30408..31910)
                     /locus_tag="IVV98_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7806506.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            32169..34163
                     /gene="uvrB"
                     /locus_tag="IVV98_000833"
     CDS             32169..34163
                     /gene="uvrB"
                     /locus_tag="IVV98_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP7806507.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            34173..36989
                     /gene="uvrA"
                     /locus_tag="IVV98_000834"
     CDS             34173..36989
                     /gene="uvrA"
                     /locus_tag="IVV98_000834"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP7806508.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            37252..38517
                     /locus_tag="IVV98_000835"
     CDS             37252..38517
                     /locus_tag="IVV98_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAP7806509.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            38521..39252
                     /locus_tag="IVV98_000836"
     CDS             38521..39252
                     /locus_tag="IVV98_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP7806510.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            39387..40271
                     /gene="rapZ"
                     /locus_tag="IVV98_000837"
     CDS             39387..40271
                     /gene="rapZ"
                     /locus_tag="IVV98_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP7806511.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            40268..41266
                     /locus_tag="IVV98_000838"
     CDS             40268..41266
                     /locus_tag="IVV98_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP7806512.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            41300..42235
                     /gene="whiA"
                     /locus_tag="IVV98_000839"
     CDS             41300..42235
                     /gene="whiA"
                     /locus_tag="IVV98_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP7806513.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            42778..43428
                     /locus_tag="IVV98_000840"
     CDS             42778..43428
                     /locus_tag="IVV98_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806514.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            43615..>44177
                     /locus_tag="IVV98_000841"
     CDS             43615..>44177
                     /locus_tag="IVV98_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAP7806515.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        14821 a         7601 c         9467 g        12288 t
ORIGIN      
        1 aattggaact gcgatttgaa tcgcagttcc aattttttaa tgtaaaactc agaaaaaacg
       61 agtatactaa aaggtactga aaaagaagag gataagatgc gatcaattgc attgtttctc
      121 atcagaaagg gcgtatatct ttgtcagaaa aacgagattt atttgaaaaa ctgttggaac
      181 aaatccaact agaggaagca gaaaaaaatc atccactgct tactgctggt gaaatggata
      241 gtgtagtggt ccatcgtaaa tcgcgtttat gggaatttac gctgcatttt tccaaaattt
      301 tgcctattat gctatatcgg tcattgactc agcatctgac tatcgctttt aaagatattg
      361 cacaagtcaa actgaatatc ttagcagatg accagacatt cgatgaacag ctcttgcaag
      421 attactgggc ccaagctttg gaaaatcagc aatgcgatac accactagca cagcaagtat
      481 tgaaaacgca ggtacctgtg ataaaagatc gtaaagtcat cttgccaatc gacagtacag
      541 gagctatttc ttatttgaag caacaatact tgccattagt agaagagttg ttcgtcagtt
      601 acggattccc aaaatttcgt atcgaaccag aagtggatga gcagcaagcg gaacgagtat
      661 tgaaactttt tgaagaacgc aaacaagaac aggcagaagc ctttatgaag caagcagctg
      721 aaagtctagt tgtccacgaa caaaagaaaa aggaaagaaa agagcaatcg ccagctcttg
      781 aaggacccat ccacatccag ctaggacgaa atattccagc cgatgaacca acgacaccaa
      841 tgatcagtat cgttgaagaa gaacgaagag tcacacttga ggggtacgta ttcgacaaag
      901 aagtcagaga actacgttca aaacgcaaga tcttgacttt gaaaatcaca gattatactt
      961 catcatttat cgtcaaaaaa ttctcgaacg gcgaaaaaga tgaacaagta tttgatgcga
     1021 tcagtgtcgg tagctggtta aaggtacgag gaagtattca agaagatacg tttgtccgtg
     1081 atttggtcat gaatgcgcaa gatatcatag aagtcaaaca tacacctcgc aaagattatg
     1141 ctcctgaagg ggaaaaacga gtagagcttc atgttcatag caatatgagt acgatggatg
     1201 caacaaacag catctctgat cttgtggcac aagcagggaa atggggacac cgagctatcg
     1261 ccattacaga ccacggtggt gcgcaagcct ttccggaagc acatagtgct ggaaaaaaag
     1321 caggtgtgaa aatcttatac ggcgtggaag cgaatgtcgt agatgatggt gtcccaattg
     1381 cttataatga tgcacatgaa gcattgagtg aagccacata tgtcgtattt gacgtggaaa
     1441 cgacaggatt gtctgcagta tatgacacga tcatcgagct agccgcagtc aaaatgtata
     1501 aaggaaatgt gatcgaaagc tttgatgaat ttatcgatcc aggacatcct ttgtcacgaa
     1561 caacggtaga tctgactggt atcacggatg gaatggttcg aggatcaaag tcggaagaag
     1621 aagtattgcg gatgttcctt gaattttcaa aagatacaat tttggtagcc cacaacgcgg
     1681 cttttgatat ggggttcttg aatactagct acgcaaggta tggtattcct gaagcggcca
     1741 atccagtcat tgatacgttg gaattagcta gatatctgta tcctcaattc aaacgtttcg
     1801 gattaggtgt gttatctaaa aaatttggtg tcagcttgga acagcatcac cgagcaatct
     1861 atgatgctga agcaactggt cacttagcat ggatctttgt gaaagaggca atggacaatc
     1921 ataacatgct ttatcatgat cagctaaatg agcatatcgg agaaggagat tcttacaaaa
     1981 gggctcgacc tttccatgta acgattttag caaaaaatca ggcaggactg aaagatttgt
     2041 tcaaactgat ttcaatgtcg aatgtcgaat acttcgaacg cgtcccacga ataccacgct
     2101 cccaattgaa aaagatgcgt gaaaatctat tgatcggctc agcttgtgat aagggagaaa
     2161 tattcgaagc catgatgcaa aaaggggtag aagaggcaag aaaccgagca aaattctacg
     2221 attatattga agttatgcca aaagcggtct atgcgccttt gatcgagcaa gaattggtaa
     2281 aaaatgaaca tgatttggaa gaaattatcc aaaatttggt agaaatcgga aaaagtttgg
     2341 ataaaatcgt tgttgcaaca ggtaatgtac attatctgaa cgaagaagat gccatttacc
     2401 gaaaaatttt gatcaattct atgggcggag cgaatccgtt gaatcgtcat agtttgccgg
     2461 atgtccattt ccgaacaacc gatgagatgc taactgcatt tcacttttta ggggaagaaa
     2521 cagcgaaaga gatcgtagta gaaaatacga ataaaatcgc agatatctgc gaagaagtga
     2581 ttccagtcaa agatgaactt tatacaccga agattccagg ttcagaagat gaaatatcag
     2641 aattgagtta cacaaaagca aaacaaatgt acggagatcc gttacctgag atcattcaaa
     2701 aacgattaaa aaaagagttg aattctatta atggtaatgg cttctcggtt atttatctga
     2761 tcgcccaaaa actagtgcat aaaagtaatg aagatggcta tctagtaggt tcacgtggct
     2821 ctgttggctc tagctttgtt gcgacgatga caggaatcac tgaagttaat ccgttagccc
     2881 ctcattatta ttgtccagag tgccaatatt ccgagttttt tgaagatggt acgtatggtt
     2941 ctggatttga catgccagaa aaacaatgtc caaaatgtgg tgcacgctta aacaaagacg
     3001 gtcatgatat tccatttgag acatttttag gattccatgg agacaaagtg cccgatattg
     3061 atttgaactt ctcaggtgat tatcaagcag aagcccataa ctatacgaaa gtattgtttg
     3121 gcgaagacta tgtttaccgt gccggaacga ttggtacagt cgccgacaaa acagcatatg
     3181 gctatgtaaa aggatacgaa agggacaata atctgcagtt tcgaagtgca gaagtcgaca
     3241 gattagcaaa aggcgctact ggagtcaaac ggacaaccgg ccagcatcca ggggggatca
     3301 tcgttattcc cgattatatg gatgtctatg attttacgcc gatccaatat ccagcagacg
     3361 atcaaaattc ggaatggaaa acgactcatt ttgattttca ctcgattcac gataatgtat
     3421 tgaaattaga tattctaggg catgatgacc caactgttat tcggatgctt caagatttat
     3481 cagggatcga tccacaaacg atccctacgg atgacccgga agtgatgcgg atatttgccg
     3541 gtcctgaagt acttggagta agtcaggaac aaatttattc caaaacaggg acattaggta
     3601 ttccagaatt cggcactcgt tttgttcgag ggatgctaga agaaacgcat cctacaactt
     3661 ttgcagaact actgcaaatt tccggactat ctcatggtac agacgtatgg ttaggaaatg
     3721 cggaagaatt gattcgacga ggagatgcga cactggcgga agtaatcggc tgtcgtgatg
     3781 atattatggt ttatttgatc catgctggat tagatagcgg gatggcattt aaaatcatgg
     3841 aaactgttcg taaaggacaa tggaacaaga tccctgatga attgcgagaa acctatctat
     3901 cggcgatgaa agaaaataat gtgcccgact ggtatatcga ttcttgttca aaaatcaaat
     3961 atatgtttcc gaaagcccat gctgcagctt acgtattgat ggctcttcgt gtcgcttatt
     4021 tcaaggttta tttccctatt ttgtattact gtgcatactt ttctgtacgt gcagacgact
     4081 ttgatctagt ctccatgtgc aaaggaaaag atgctgtgaa acaagcaatg aaagaaatca
     4141 cggacaaagg attagatgct tccgtaaaag aaaagaatca actgacagtg ctggagttag
     4201 ccaatgaaat gctggaacga ggattcaaat ttggaatgat tgatttgtat aaatcggatg
     4261 ccgttaactt tgttattgaa ggtgatacgt tgatcgcacc atttagagct gtcccaagtt
     4321 tgggaaccaa cgtggcaaaa caaatcgttg aagcaagaaa agacggtcca tttttatcca
     4381 aagaagatct tgccacccgc ggtaaagttt caaaaacatt gatcgaatat atgaacgaca
     4441 atggcgtatt gaaagatcta ccagatgaaa atcaattatc gttattcgat atgctataag
     4501 catctgtttt cctgtctgct tgtaatttta agcagagtat ggtatagttc ttataggtaa
     4561 tgatactaac tgtgagtgag cggatttttc gctcactctt tttaatggaa ttacgcactt
     4621 aattttttaa ggaggcgaaa cttttgagta gcgtcgttga aacagtcaca gaaatggtga
     4681 caccgatttt agatgaacaa aattttgaac ttgtcgaagt cgaatttgta aaagaaggaa
     4741 aaagctggtt cttacgagta tttattgaca aagaaggcgg tatcgatatc gaagaatgcg
     4801 cctttgtcag tgagaaactg agtgaaaaac ttgatgcagc agatccagat ccgattcctc
     4861 aagcttattt cctggaggta tcctccccgg gagcagagcg gccattgaaa aaagaaagcg
     4921 actatgaaaa ggcacttggt gattatgtcc atgtctcctt ataccaacca gtagatggcg
     4981 aaaaacaata tgaaggattt cttcaatcat ttgatgctga acagcttaca ttgaaaatac
     5041 gcataaaaac acgagaaaaa gaattgactt ttgaccgaaa aaatattgca aaagctcgct
     5101 tagctatcca attttaatca cggagaggaa tcagaaaaaa tgagtaaaga aatgttaaat
     5161 gcgttagacg ctttagaagc tgaaaaaggg atctcaaaag aaatcgtgat cgatgcttta
     5221 gaagcagcat tggtttctgc atacaaacgt cactatggcc aagcacaaaa cgtcgaagtg
     5281 gaatttgatc agaaaaaagg aaagatccat gtctatgcgg taaaagaagt aacggaagaa
     5341 gtgatggatt cacagttgga agtctcattg aaagatgcac ttttaatcaa tccagcatat
     5401 gagatcggtg atacgatccg ttttgaagta acaccaaaag attttgggcg gatcgctgcg
     5461 caaacggcta aacaagttat tttacagcgt gtacgtgaag cagaaagaac gattatttat
     5521 aacgaattca gtgcttatga aaaagacatc atgcaaggaa tcgtcgaacg ccaggataaa
     5581 cgttatattt atgtcaatct tggtaaaatt gaggcagttc tttctaaaca agatcaaatg
     5641 ccaaatgaat tttatcaacc acatgatcga atcaaagttt atgtttcccg agtagaaaat
     5701 acgtctaaag gtccgcaagt atttgttagc cgcagccatc cagacctatt gcgccgctta
     5761 tttgagcaag aagtaccaga agtctatgat ggaatcgttg aaattgtcag catcgcccgt
     5821 gaagctggcg atcgttcaaa agtggcagtt cgctcaaatg atccaaatat cgatgcagtc
     5881 ggtacatgtg tcgggccaaa gggacaacga gttcaagcaa tcgtcaatga attaaaaggc
     5941 gaaaacatgg atatcgtcga atggaatgaa gatccagctg tattcattgc aaatgcattg
     6001 aatcctgcac aagtcatgga tgtgatcttc gatgagacaa atccaaaggc ctgcacagtt
     6061 gtcgttccag actaccaatt atcgctagca atcggtaaac gcggacaaaa cgcacgttta
     6121 gctgctaaat tgactaacca taaaatcgat atcaaatcag aatctgacat gacggaattt
     6181 tatgaaaatc aagaacaaca aaaagaaaca gaagaactgc atgatgaagc aatcgttcag
     6241 tcagatttaa cagacgatga atatgaaaca attgcattca acaatgaaac ggtcgaagaa
     6301 aaaccagaag cttaacttta gtaaggaggc aaagagatga aacaaaggaa aattccttta
     6361 cgcaaatccg tggtttcagg tgaaatgaaa cctaaaaaag agatggtccg aatcacccgt
     6421 tcaaaagaag gggaagtatc gatcgatcca actggaaaaa tgcctggacg aggagcgtat
     6481 gtctcacttg agccggaaga agtacaacaa gcttgggata aaaaaattct cgatcgagta
     6541 ctcgaaacaa cattaacaga tgagttttat caagaacttc ttgactatgt cactcaccaa
     6601 aaagcacgta aagagttatt tggaaaatga atacagttaa tcggcaaaaa gccatgaatc
     6661 tcatcggtct agcgatgcgc gcgggaaaac taatcacggg tgaagaactg accattgctg
     6721 aaatccgcaa acaaaaagca aaattggtgt ttgtggcaac cgatgcaagc gagaatacaa
     6781 gaaaaaagat aaaagataag agttcatatt atgaagttcc ttgctttgag ctattttctg
     6841 aagcagaaat cacgcagatg atcggaaaac ctcgcaaggt attcggaata atggatgccg
     6901 gatttgcgaa gaagaccaag gagctaattg aaggttagga aggtgattgc atgggcaaca
     6961 aaagaatcta tgaattagca aaagaactca aaaaatctag taaagacgtc gtggaaaaag
     7021 cacaacaact tggcatcgat gtgaaaaacc atatgggtgc gattactagc aatgatgaga
     7081 agaaattgca acaagcgttc aaaaacccaa gcacgaaaca acaagctgca caacaagcaa
     7141 gcagaaaacc agccaatcaa cagccgaacg atcaacgtaa aaaagaaaca acgaacaatc
     7201 aacaaaaaaa taaaaataac cgcagttatc aagatcgcgg tcaagggagc ggtcaagtga
     7261 atcaaggaaa aaaaccaaca acaaaccaaa ataatacggg aaataccagc agccaaaatc
     7321 gtcaaggaac gagccaaggc ggcaatcaaa accgtactaa caataacaac aaaccaaaca
     7381 ataacaatcg cggcaaattt aataataata accgtaatcg ttataataaa aaaggtaaaa
     7441 aaggcaaaca gcaacaatca actaaaccag ctgtaccacc acgcaaattc cgtgaattgc
     7501 cagatgtatt agagtatact gaaggtatga acgtagcaga tattgcgaaa aaaattcatc
     7561 gtgagccagc agaaatcatt aaaaaattat ttatgcttgg tgtcatggtc aatcaaaacc
     7621 aagcactgga taaagatacg attgaactgt tagcgacgga ctatggcatg gaaccacaag
     7681 aaaaagtcca agttgacatt gctgatatcg ataaattctt cgaggcagaa gaagtcgatc
     7741 cagataaatt agtctcacgt ccgccagtcg taacgattat gggacacgta gaccatggga
     7801 aaacaacttt attggataca ttacgccatt cacgtgtaac aagcggcgaa gccggcggaa
     7861 tcacacagca tatcggtgcc taccagatcg atattgatgg taaaccaatc actttcttgg
     7921 atacaccagg acatgcggcc tttacaagta tgcgtgcacg tggagcaagt atcacagata
     7981 tcacgatctt agttgttgct gcagatgatg gcgtcatgcc acaaacagtt gaagcaatca
     8041 accatgccaa agctgcaggc gttccaatca tcgtcgctgt aaataaaatt gataaaccag
     8101 gtgcaaaccc tcaacatgtt atgcaagaat taagtgagta tgagttaatt cctgaagcat
     8161 ggggtggaga aacgatcttt gttgagatct cagcgaaatt cggccaaaac atcgaagaat
     8221 tgctggaaat gatcctgtta gtcgcagaag tagaagattt aaaagcagat ccaacacaac
     8281 gcgcaatcgg aacagtgatc gaagcacgtc ttgataaagg taaaggtcct gtgtcaacct
     8341 tacttgtcca agaaggaaca cttcatgttg gtgacccaat cgttgtcggt aatacttacg
     8401 gacgtgtccg tgtaatgaca aacgatcttg gccgtcgcga taaagaagca ggacctgcaa
     8461 cgccagtaga aatcactggc ttgaatgatg tacctcaagc aggtgaccgt ttcgtagtct
     8521 tcgaagacga aaagacagca cgtgcagcgg gtgaagaacg cgcgaaacgt gcattattag
     8581 aaaaccgtgc tgccacaagc cgtgtgactt tggataactt atttgaaagc ctgaaagaag
     8641 gcgaattgaa agaagttaac gtaatcatca aagcagatgt acaaggttca gcagaagcac
     8701 tggctgcatc attgaagaag attgatgtgg aaggtgtccg tgtaaaaatc gtccattcag
     8761 ctgtcggagc aatcaatgaa agtgatgtaa ccttagcagc agccagcaac gctattatca
     8821 tcggtttcaa cgttcgtcct acaccgcagg caaaagtgca agctgatact gaagaagtcg
     8881 atattcgtct tcaccgtatc atctataaag ccatcgaaga aatcgaaact gcgatgaaag
     8941 ggatgctaga ccctgaattt gaagaaaaaa tcaccggtca aatgatcgtt cgtgaaacct
     9001 tcaaagtttc taaagttggt acgattgcag gtgcctatgt aacagaagga tatattcgta
     9061 gagatagcgg tgtccgtgta atccgtgacg gaatcgtaat ctatgaaggc caacttgcaa
     9121 gtctgaaacg attcaaagat gacgtgaaag aagtcaaaat gggttatgaa tgtggtgcaa
     9181 tgattgaaaa attcaatgac atcaaagtag atgacgtaat tgaaggattt atcatggaag
     9241 aagtcaaaaa tgactaaaaa ctgataaaag gaggccaatc attatggcta actaccgtga
     9301 ccgccgagtc ggtcaagaaa tcttaaaaga agtcaatgat attttgcgca aaaaggtccg
     9361 tgaccctcgt gtggagaacg taacgatcac agatgtgaaa gttacggggg acttacagca
     9421 agcaacgatc tattacagca ttttatctga cttagcatca gataagaaaa cagcacaaga
     9481 tggattgaat aaagcatcag gattgattcg tcgagagtta gggcacaatc taagtattta
     9541 taagacacct gaattgttct ttgaacttga tgaatcagtt gtctatggca accatatcga
     9601 tgaattgctt cgcgacttga acaaagacta atcaaaaact cccgcaaatc ctgtgaaatc
     9661 aggggttgcg ggattttttt gttttcatta agacgtatta cctaagagtt ccatgacttt
     9721 agtcttgcgg cgtgtcagct aaccaaaaaa gagaaaaaga aaagtaaaaa attcgacttt
     9781 cttttttcta gtagtatata aatttttgca tatagataaa gatcaagata ccgataacgg
     9841 aagctagatt gtaatctatt ttagtgacag tcaggtatag ccaagtaact agaagatcag
     9901 tggaacctgc accataaaag tttgagtttg tcggtccgtt gacagttaaa agaaaaatca
     9961 cgttgaagtt attgatattt ccgattacgc cgcttcgatt tggtcacgat ccaaattttg
    10021 gataatccct gtagaaatta gcatagtagc tgggatacca attcacatat tgacaaagat
    10081 aacagagact tttacataaa acggatcaat caggaaagga attgctcgat ccagccccag
    10141 ttttccagca atgtgttaac tggcccagcg tcattcagca aattatgcat gatgaggagc
    10201 gaaatgaact gcggaacagc cattgtgata acgacaagtt ttttggatca atgtaaaaaa
    10261 cgtcagcgaa aggaaaaatt tcgtggtttt ttatacctgt tcatttggct agatataaaa
    10321 tccaaacaaa tgaacagaag tgcttattag gtttcaattg ggagtatctg cgctagaata
    10381 agagtaataa tgaaaaggag tgttatgtat ggattattct agtaaagaat actttgataa
    10441 aatgacggct tggtggcgtg ctgctaatta tctttctgtt gggcaacttt atcttaaaga
    10501 taacccctta ctgagacgta cactgaaacc cgaagatgtc aaaaaacatc caatcggtca
    10561 ttggggaacg attcctggcc aaaattttat ttatgtccat ttgaaccgag tcatcaataa
    10621 atatgatttg aacatgtttt atattgaagg gccaggacac ggcggacaag tcatggtatc
    10681 gaatgcttat ttagatggaa gttacacaga gatctatcca gaagtaacgg aagatgagac
    10741 aggaatgcaa aaattattca aacgattttc atttcctgga ggcattgctt ctcatgcagc
    10801 accagaaaca ccaggttcta tccatgaagg cggagagctt ggatactctc tttcacatgc
    10861 agtcggagct gtattagaca atcctgaagt aatctctgct gtcgtgattg gtgatggtga
    10921 agcagaaacc ggtcctttag ctggaagctg gttctcaaat gtctttatca atccagtgat
    10981 agatggagct gttttaccga tccttcattt aaatggtgca aaaatagcca acccaacgat
    11041 cttggcacgt aaatcagatg gagaattagc aaattacttt aacggacttg gctgggaacc
    11101 tttctttatt gaaggaaatg attcagaaaa attaaatcct gttatggctg aaaaaatgga
    11161 tcaagcaatc gagaaaatta aatccatcca aaaagaagct cgcctgaaga cagcaacaga
    11221 tgtcgtgatg ccaaaatggc cagtattgat cgtacgcaca ccaaaaggat ggaccggtcc
    11281 aaaagaatgg gacggggaac caattgaagg aaccttccga gcacaccaag taccgattcc
    11341 tgtagatcaa gaacatatgg atcatgcaga tgctttactc cgttggctga aatcctatga
    11401 accagaaaaa ttatttgatg cacaaggacg tattttagaa gaaatcagag aaatcgcgcc
    11461 tactggtgac caaagaatgg caaaaaatcc tatcaccaat ggtggaatcg atccaagacc
    11521 gcttattatg ccagattgga aaaaatatac tttgcaattt gaaaaaccag gctccgttaa
    11581 agcagaagat atgaccgaac ttggtaaatt cgttcgcgag atcattgaga aaaatccaga
    11641 aaatttccgt atatttggac cagatgaaac aaaatcaaac cgattgaatc aagttttcaa
    11701 aacgacaaat cgccaatgga tggaaaaaat cgaaccagaa aatgatgaat ggctttcgcc
    11761 atctggtcgc gtcatcgaca gtcaattatc ggaacaccaa gatgaagggt tcttagaagg
    11821 gtacgttctg actggacggc atggtttttt gcaagttacg aatcattctt gcgagtggtt
    11881 gactctatgt tgactcagca cttcaaatgg atgcggaaat cacatgacct ttcttggcga
    11941 aatgattatc cttcgctaaa tctcattgca agctcaacag tcttccagca agatcacaat
    12001 ggatatagcc accaagatcc aggaatattg acacatttgg cagaaaagaa ggcggagttc
    12061 atccgtgaat atctgcctgc ggatgcaaat acattgctcg cagtcatgga taaagcattc
    12121 cgctcgtcag aaaaaatcaa tttgatcatc tcttccaaac atccgcgtgc tcaattttac
    12181 tcagcagaag aagcagccgt cttagtgaat gaaggcttga aaatcattga ttgggcttcg
    12241 acagcaaaag aggaggaacc tgaattggtc attgctgctg caggaacgga atctaactta
    12301 gaagcattag cagctgtaac tttgctgctg gaagaattcc caaaactaaa aattcggttc
    12361 atcaatgtcg tagatttatt gaaattacgt catccaagtc aagatccgcg tgggttgagc
    12421 gatgaagaat ttgatcaata ttttacaaaa gacaaaccga tcttatttgc tttccacggt
    12481 tatgaaacat tggtccgcac gattttcttt gatcgtcata accatcattt aatgattcat
    12541 ggctacaaag aaaatggaga tatcacgaca ccatttgaca tgcgtgtagt aaatgaactt
    12601 gatcgttatc atttggcaaa agacgcagct ttaaaaatca aaggaagtca agcagaagat
    12661 tttgcgaaaa aaatggatca gaaattacaa gaacatcaaa actatattcg tgaaaatggt
    12721 attgatctgc cagaagtatt ggattggaaa tggaaaaatc ttgaccaata aaatgataaa
    12781 atcgatcccg caaaatagaa ttttttacat tgattaagaa actgaaaaaa taaataaaaa
    12841 aaacggaaaa aagactggaa gaatggccag tctttttttt cgtttttggg aagtgaaaac
    12901 caaactattt acctgtaagc cacccataaa tccaatcaaa tggtgcaaag aaaaaatctt
    12961 ccattctatt ccctccttta aaaaagcata acatgatttc tatttacgtg agcatgaatt
    13021 ttgttacgtt tttattgccg aaaaataaaa accgttcatt atgatgtcaa attcgtcagt
    13081 aattgatgca atgtgttata ataattcagt taaatcaaaa atgaaatgga gaaaagacat
    13141 ggacgggtta ttacctttat ggaaagaacg cggaatgaca agtcatgatt gcgtattcaa
    13201 attaagaaaa atcttacata cgaaaaaaat cggacatggg ggtacgcttg acccagacgt
    13261 agacggtgtg ttgcccattt gtattggaaa agccacaaaa gttatcgaat atttgacaga
    13321 ttctgggaaa atctatgtag gcgagataac tctaggtttc agtacaacga cggaagatcg
    13381 atccggagaa cgggtagaaa caaaaccagt agatatgtct ttatctgaaa aaaaaataga
    13441 tgaagtgatg gcttcattta ttggtgagat cacccagata ccaccaatgt actcagcggt
    13501 aaaagtcaac ggtaagcggt tatatgaata tgcccgcaat aatgaaacag tggagcgtcc
    13561 tgttagaaag gctcagattt accgttttat ccggacaagt gaattgacaa gagacgaagt
    13621 gacaggaacc atttcttggc gcttcgaagt agaatgcggg aaaggaacct atgtccgcac
    13681 attagctgta gatacaggca agaaacttgg ttaccctgcg cacatgtctg atctgacccg
    13741 aacagcaagt gccggtatgt cccagaagga tgctctgaca ttagaagaag tagctcaagc
    13801 tgtgaaaaat gggacaatcg atgattgttt gctgccaata gaaaaaggag tggaacggtt
    13861 caaacgagta gatattactg atgaagtatg gcagaaagta aaaaacggta tgagacttga
    13921 ttatactgta tttgcgctcc cagaaatgcc gtcagaagaa attgctttgt tttataaagg
    13981 aaaagttgtc agtatttatc agccaaaccc gaaagaaaaa aacaaattaa aacctagtaa
    14041 agtattgaga aatgaggaat aacgaatgaa tatcatcaag atcagacatc cttaccaatc
    14101 agaacaaatt ccagaagacg atgtcgtttt agtgctggga tttttcgacg gcgtgcatat
    14161 cggacaccag aaagtcataa agacaggtat ggaaattgca caaaaagaag gattgaaatt
    14221 agcattgatg actttcaatc agcatccatc tattgtcttt aaaaagatcg atcctagcag
    14281 cgtgaaatat ttgactagcc ttaagcaaaa agaagaaaaa atggccgctt tgggtataga
    14341 ttatttatat gaagttgatt ttacttcttc ttttgctcat ttagcaccgc aggaatttgt
    14401 tgatcaatac atcgtagggt tacatgcaaa atatgctgtt tccggttttg attatacgta
    14461 tggaccaaaa gacattgcag atgtcgctca ttttcctgaa tatgccaaag gaagattcaa
    14521 aatcgtcaca gtttctaaag aagaagaaca aggtgaaaaa atcagctcta cccgtattcg
    14581 tggattacta gacagcggac aagtaaaaga agcagcaaaa ctattaggtt gcacatatga
    14641 ggtagaaggg gtagttgtcc atggcgatgc acgaggcaga ctactaggat tccctacagc
    14701 aaatgtcaaa gtaaagagca cggttcattt gcctaaagaa ggtgtttatg tgtcggaaat
    14761 aaaaattggg gaaacatggt atccagccat gggttcaatt ggacataatg atacattcgg
    14821 tgaaggacgg gagctgactg tagagttgta tattttggac tttaatcaag atatctatgg
    14881 tgaacatgtc gcggtacgct ggaatcaatt tttaagagat caagtgaaat tttctagtgt
    14941 agaggaattg attgaacaac tcaaggagga tgaacaagca acagctgaat atttttctca
    15001 gcaataaaac attatgcata aaatctcttg tttatgtata actagcaatt acaataaaat
    15061 gggtgataaa taagcccagg aaaggggctg tgacaaaagt cttgtcacag cctttttttc
    15121 caaataaatg gtttttcaga agtagcttct tcggaaataa gccgaaattt cttgaagctg
    15181 accacttctg tcacaacctc tttctttata gaaataaaag gacactagca attcatgaaa
    15241 acgattgcta gagcgtatca tttgctttag actatatatc ttggtgtaca ctcactttaa
    15301 ggcggaaata aaagttatcc gtaataacag gtttaggtat gaaaaaggag tgggtactat
    15361 gtacaaggaa ttagaaaaca aagtcgcagt agtaactggt ggctcaaagg ggattggaac
    15421 agcgattgct caacgattcg ggaaagaaaa aatgaatgta gttgtcaact ataactcgga
    15481 taaagaagga gcagaaaaag cagtcaaagc aatcgaagag gcaggcggaa aagcagtctc
    15541 tgtacaagca gatgtcagtt ctgaagaagg aatacagcgt ttacttgata cggctttaga
    15601 aaattttggg acactggacg tttgggttaa taatgctggg atggaaaatc agcatccaac
    15661 ccatgaactt agccttgaag attgggaaag agtgttaaaa gtcaatttga ctggcgtttt
    15721 tatcggaacg aaagcggctt taaattactt tacagagaat aataaaaaag gaaatatcat
    15781 caatatgtct tctgttcatg aacagatccc atggccaacg tttgctcatt acgctgcttc
    15841 aaaaggcggg gtaaaattat ttaccgaaac ggtagcaatg gagtatgcac cgaagggaat
    15901 cagaatcaat agtataggcc ctggtgctat ccgtacacct attaatgcgg caaaatttga
    15961 tgatcctgaa caaaaagaac tcttggaaag tatgatccca ctaggacgcg taggtgaacc
    16021 aaaagaaata gcggcgacag ctgcatggtt ggcttcagac gaatccagtt atgttacagg
    16081 tattacacta tttgcagatg gtgggatgac tttatatcct tctttccaag gtggaaaagg
    16141 ataagggtga ataaaaatgg gtttattgat tgcattgatc ccggcagttg gctgggggat
    16201 ccagccactg attttgaaaa agattggtgg cagaccaaca aatgagatat taggaactgg
    16261 tattggagcg gtgcttgtcg gcttactcgt tcaattattc gcttctccag ctggtatttc
    16321 agtgactaca tttttgatta gtttactttc tggtgcattt tgggttattg gacaaacagg
    16381 acagtataca tctttcaact tgattggtgt ttctaaaacg atgccaattt cgactgcatt
    16441 acagttagtc ggaacctcgt tgattggtgt cttcgctttt ggagaatggt ctggaagtat
    16501 ggggaaaatc attggagcag cagcaatcat tcttcttgta tttggttctg ctttaacggc
    16561 aatcagtgat gatcctggaa aaaaaggcgg tatcacaaaa ggaattagtc tattagcatc
    16621 aacaagtatt ggttattggg tatacagtgc attgcctaaa ctagttgatg caagcggact
    16681 ttccattttc tttccgcaaa tgatcggtgt ctttttaggg gcagtgattt atgtgatttt
    16741 ccgtaaacca accgcatttt ctgaagacaa gagttggaaa gcaacgatcg ttggagccat
    16801 ctttagtgtg tcagcattgg cttatatttt ttcagcaaat gaaaatgggg ttgctactgc
    16861 atatatcatt acacagctaa acgtagttat ctctacatta ggcggtatgt acatcctgca
    16921 tgaaaataag acaccaaaag aaaaaaaatt aacgattatc ggattattgc tgatcgtagt
    16981 aggaagcatg gtcacggtct ttatttgagg ataaagatgg taaaatttca tttattaaaa
    17041 aaatatttgt ttgaaccaaa cagtaagtac ttataaaaaa atagcgctag aatttccaac
    17101 atctctggaa tttctagcgc tttttaattg tttaagatac aagggaaata tctgtctgga
    17161 tcaataattt ttcattgatc cattgactaa agtttacgac ataattgaag ttaccaccga
    17221 ttagtatctc cgcatgattg tctttataaa gatcgtattg taaaagacgg tcttttttat
    17281 ttgcgtaaac atcgttatgg tactggacta attgttctcg gaattgattg attgctgtaa
    17341 aatcacgata ttgaaggttg aaacgcatcg tgattggtgc atttagcatg aatcgctgca
    17401 tttcttttgc tgcttcctct gcttgatctc cgtataggaa ctcaaaaaga ttacgttcag
    17461 aaaatttcca ttgcccgcca acctttgttc cttttagttt tccttcatga agataatttc
    17521 tgatagaacg tgtagtaaca cctaattgtt cggctaattc atttactgag taaaaatctt
    17581 tcaatgttca ccctcctatg tgaatggttc tactgactta gttgatattt gcttaatcac
    17641 gaaatgtaga aagaacgatt ttaattaagg tcattgtaaa aatcaagtca gaaaattcta
    17701 acttttattt ctctaaagaa attcgttctc tcctaaagtg atattatatt taaatatacc
    17761 tgaaaataat gggcagtatt atgaaagatc actgatattt tctcgtattt tttccttatt
    17821 caaaagtttt gcaggaaaat tgctgaaaaa ataattttac taagtagaaa attcaaagcc
    17881 attcaatcag tgattttttt cagcacaaga aagactcctt ataaaaatag cagatacttt
    17941 gtcaattaag tgtttaacca gggatgataa aaaggatagg attgaacaaa acctgtataa
    18001 ggtgatgaat agtttcctcg ccagtaaaag gtttattcgt ataaagcttt atcgccaaaa
    18061 tttatcatga ccttttttat cttcaatatt aaatgaaatc aattgttcaa tcaattccca
    18121 gttgattaca cttttccaag gaactttgat gacgttatcc gtatatacgt agcctgcttc
    18181 ttggatattt ttttcaaggg cacgaatcgc tgctttttcc ggtgcgatag aaaaatgatt
    18241 tttagcaaaa ctaaatgcaa taataaaggt accatggtca gtaaacatag gttggttcca
    18301 ttttacagtt gtgtctagct ggggatacgt ttctgttatc ttagcaaaaa ggtctttgat
    18361 cttttgttga tgttcttttt ctttgatttg attgatgatc ggctgaaatt tttccattct
    18421 aaaacgcctc cattaagtgg tttgatttat tttaccagaa aaacaatagt tatgtataaa
    18481 aaacgaacaa aacacaagta atgttgtaac cgctatattt atatgataag atgtctcaaa
    18541 taataaaata gaaaagagac ataaaaatga ttgacttggc aaagaaattc ttacacgaaa
    18601 atatatattt tgagttgtat catcatcgag ccatttatac aaatgaagat gctttggtaa
    18661 taaagaaaga acaaggattt acaggtacag agaccaaaag cttattctta aaagataaaa
    18721 aagataataa ctacgtatat ctgactttta ctacgaaaca aacggatttc aaagcattag
    18781 ggaagatcgt cggtaaaagg ctttctattg tttcatcaga acgcatggaa gaacaaacgg
    18841 gacaaaagca gggcgctgtt tctccgtttg gttatgaaaa acagattccg attattattg
    18901 atgaagagct cttatcaaat gaaaaacttg tttttgcacc aggtagacca gatcaaacga
    18961 tggtcatcca aacggttgac ttaaacaaaa tcatccagct acttgagatg ccgatatttt
    19021 tgatgccggc aaacgaaaaa aacaattaac caagtaaaat agtgcatact tggaggtgaa
    19081 gcaacatgat aagttatcca ttattagaaa gaaatgcaac gattggggtt actgcaccat
    19141 cctcaggcgt atcagaggaa caccattcgt tactcgaatc agctttaaag agaatggaag
    19201 aaaaatcttt ccaagtagtt actggaaaga cgctttggac gcaagataag gaaaaatcag
    19261 gtccagcaag aaaacgagca gatgaattca atcaaatgat gcaagatgaa aatatccaaa
    19321 tgatctttcc gacttgggga ggagaattat tgattgagat tctcgatttt gtcgattttg
    19381 atgctctaca accaaaatgg atagtaggtt attcagatat tagtacgttg ctacttgctg
    19441 tcacattaaa aacagggata gccactgcac atggaactaa ccttattgat ttaagaggag
    19501 agtacttgga tgaaacgaca gcaatgtggg aaagtgtact gaaaacaaga gaaggagaat
    19561 cgattctaca gcaatcttct gaaaagtatc aaaaagtgtg gccccatgag cattcatcat
    19621 cttctgtttt ccatctcact gaaccaacaa attggcaatc agtcagcgga gatgcagtaa
    19681 ggatgaaggg acgattatta ggtggttgta ttgatacgat caggcattta atcggtactc
    19741 cttatggaga tgtccaatct tttaaaagaa agtataatga tggaaagccg atcttgtggt
    19801 ttctagaaaa ctgtgagcta tcgtcagttg atttaagaag atcacttgtt cagatgaaac
    19861 tggcaggctg gtttgatggc agctcgggga tcatgttcgg tagaagtgcg gcagaggatt
    19921 tgttagatta taaaatgaag gatgtatacg aagatctgtc aaaggaatta aaactaccga
    19981 tcttgtatga tattgattgt ggtcatgtac cgccacaact gacattgatt aatggtgcct
    20041 atgcagaagt agcggtagaa gatagaaaag cgactgtttt gcaaacgttt atttaaaaaa
    20101 ttttttcctg ccttggagtc tatcaaagac caataaatct aaatagaaaa gaaagtgaaa
    20161 gaagctgaca aaatgctgtc agcttctttt tgtataacat attagaaagt ctaattatct
    20221 ataactgtca catcgattaa ctgtttcacg tcattgggat ttcctgtagg aatagctact
    20281 acagatgcat tatcaatgat ttcttgagtt gtttctctaa tgaacgctgg ataagatgtt
    20341 tgatctgcag gcatttgcca atgtgaagga actggataac tagtgattgt cccgtcatgg
    20401 ttacttgaat acactaaaac tccctggtaa ctgtatttcc cagtgagcat aaccacatct
    20461 ttcggataga ctgcactccc tgcatcataa ggggcgatag gtgttcctgc aggataatga
    20521 ataacatgta attcgaaatc acccgatgta tctctaaaag tattacctct aatagctagc
    20581 caaacacgtg cgtactcaat ttgtagatca gaatatcctg ctaacggatc tattgactga
    20641 gaagactgtg aggaggttgt gtctattgtt gaagaagaaa tatttgtctc aactgtacta
    20701 ctagatgtag aagaagtatt gggctctgag actttactgc ttgttgaaga tgtattcgtt
    20761 tcagtagaag ctgatttctg agtacttgat ttttcagctg aactggtttg tctgattgaa
    20821 cttttgtctg tggtcgcaga tggatcacta ttttctttac taggagacgt acatcctaca
    20881 aggaataaag agaccaacaa taaaataaaa cctaactttt tcatataaaa tacctcatta
    20941 tttttttaat accagtatag cataatcctg aatttttgaa tccgtaaaac cttgtctatg
    21001 aatataaata gagtgtatct tctttgataa atgtcagaaa aagtgtgaca aataatcatc
    21061 agtaaaatta cttgtcacac tattgataag gagtatttaa ttgaagagaa tgattaggag
    21121 aaaggatctc cgtacttttt atagtaatca tagaatccaa gtttgtatag acgaatcgtt
    21181 ttttctctta tttcttctgt ttcaaaatgg actgcttgaa gaatcaagtc tgtgaattct
    21241 ataggagctg ttccattcgc agtaatcaaa ttacgatctt tcacagcttg ttgttctata
    21301 aaatcttctt tattctgata attttccgat tctaaccaag gaaattgcgc atttccggtg
    21361 tgtttgtaac cttgcaataa tccgctctga gctaaataat caactgcccc acaaatagca
    21421 gctactggta cgtctgtttt taacaattta tcgattattt gatataaatg atgatttttt
    21481 atgtcccatg aattgccacc gatcataata aaaaggtcaa ctttttcagg tatttgttcg
    21541 attaagtaat cgatttttgt ttttaatcct ccaatggaag tgacctctga ttggatagaa
    21601 gcagttttgt tttgccattt ctcattttgg tttagtgtgc tagtaatata agcaccttcc
    21661 caatcggcat attcctctaa tagaaacgta atcgcagttt tcattttcaa gctctccttt
    21721 actatctata acaaggacaa cagttttaac ctacagacat tcattaaaat tgggtagcga
    21781 cagcgaaaac aacaattctt aagttttaga cagagtatac agatagtcaa cttaattaaa
    21841 tacgaactaa ataaaaatga caggtaatca tttttgttta ccagcattat aacattttgc
    21901 atacatggat gacaaaagaa ccaattccca cttgcttgag tacaatatta aaagaaactg
    21961 gaaggcaaaa agtaattata gaaacgaaaa ataaatcata tcgggcactc agacatgaaa
    22021 acaaccctag agatatataa ctaggtaacc agtttaatga aagaaaaaat catccaagaa
    22081 gtcgattctt ggatttttta gtggatttgt tcgccaaata cgtttagtat gcgtatatga
    22141 gaggttgtaa gcaaagcgtt gtggtctgag cacttaagga ggaatctgtg aaaatagctt
    22201 ttcatatttt tgcagatttt gacttaatgc cgaaggtcag ctttgcgatt accgtttatc
    22261 gagaggctgt aaaagcaccg tgtagctccg atgacaataa gcaagcattt ttagagctag
    22321 gtttccttga ttctaaatat gcggcttatt tcaatgagtt ggtgcttgaa cgcgatttta
    22381 agaaggtcga aaacaggcac gacttttcga cgtaaggaga aagaatttca atgatagaaa
    22441 caataaatcc cgcagaaaac aaggtttctg cgtacattca tatcccattt tgcgagcata
    22501 tctgctatta ctgtgatttt aataaagttt ttttagaagg gcagccagta gatgagtatg
    22561 tggaaatgct gctgaatgaa atgaaaataa tgctagaaag tcatccgaca gcgaatttag
    22621 aaacacttta cgtagggggc gggacaccaa cttctttatc tgctaaacaa cttgatcgac
    22681 tgttatcagg tgctagagag atcctgcctt ttcaaaatgg taatgagttt actgtagaag
    22741 cgaatccagg tgatttgacc cgtgaaaaac ttcaagtaat gaaaaactat ggcgtcaatc
    22801 gtttatccat gggagtgcag acatttgata atcgcttatt gaaaaaaatt ggacgtaaac
    22861 acaccgcaga agatgtgtat caaactatgc aatttttaga agcagaaaat tttaccaatg
    22921 taagcatcga tttgatttat gcattaccgg gacaaacact agaaggatat ctggatactt
    22981 tggaaaaagc tttggctttg gatctgcctc actattcttt gtactcattg atcctcgaaa
    23041 acaaaacaat gttcatgaac tgggtacgac aaggaagact cgaactgcct gatcaggaaa
    23101 cggaaaccag aatgtttgaa gagacgattg aagcaatgga aaagcatgga cgtcaccaat
    23161 atgaaataag taactttggg ctctccggac atgaatctca acataacctc atgtactgga
    23221 acaatgccca ctattttggg tttggagctg gtgctagcgg ttatcttgga gatattcgtt
    23281 accgcaacaa aggaccaatc caacactatt tacgcccatt acgagcaaat gaacgcccgg
    23341 tattggaaga agaaaaattg acacgaaaaa atcaaataga agaagaaatg ttcttaggac
    23401 taagaaaaaa aacagggatt actaaaaaac atttctatga tcgctatcaa aaaacaattg
    23461 aatcggtgta cggtgatgtg ctaagggaat tagagcaaga agggttactt gttaatgaag
    23521 aagaccgtgt ttatttgaca ccaagaggga cctttttggg gaacaatgtg tttgagcgct
    23581 ttttgtttga aaaatagttt aaagaatatt tgttttttat ctgaatttaa ataaaaaaag
    23641 ttcaaaaata caataaagga ctattgaaac gttgatataa ctggatttac atcaattatt
    23701 tagaattagc actcttgtgt ttagagtgct aaaaaatgga gtctttctct tgacaggaga
    23761 agggcttctt gctatattta taagtggatt agcacttaga atatatgagt gctaatgaga
    23821 ggtgaggaag atgttaacaa agcgacaaaa cgacatttta cgtctgatca tccaacacta
    23881 tacgagtagt ggcgtgcccg ttggttccaa aacattgatg tctgagggag tcaaggccag
    23941 ctcagcaacg attcgcaatg atatgaaagc attagaagat gaaggattgc tgttgaagac
    24001 tcactcttct tctgggcgga ttccatctgc tttaggctat cgttattacg tggatcattt
    24061 gttaaaacct gctcgcgtag cagaagatga tttgctgctg attcgtcagt ctctaggcag
    24121 agaatttcat gaaatcaatg agattattaa gcaatctgct gagatattat ctgagctgac
    24181 aagctatacg actttttcat tgggacctga aataaaagac cgccgactga ctggctttcg
    24241 tatcgtaccc ttgaataatc gacagattat tgctatcgtc gtaacagata tggggaatgt
    24301 agaaagccaa gtgttcactc ttcccgaata tatgggaagt caggaactag aaaaaatggt
    24361 acagattgta aacgaccgtc tagtcggaga tcctctgatg acggtgtacc ataaacttcg
    24421 tacggagatt ccgatgattc ttcataaata tttccaaacg acagaaggga tgtctcagtt
    24481 atttgacacc gttcttggtc atgtttttga agataaggtt tatgtcagtg gacaaatgaa
    24541 tctcttggat tatgagcccc gtcaagatct tgatcagttc aaatcgatgt tttcttttat
    24601 gaaagactca gacggactta cacaaatgat cactccgatg gatagcaata ttcatatcaa
    24661 gattggtgct gaattaggca atgatttatt gcagaatatg agtatgattc aagcaagtta
    24721 cgagatagat ggtcatggaa gaggtacaat agccttgtta gggcctacta gtatgcctta
    24781 ttctcggatg ttcggtctag tcgatgttta tcgaagagaa ctagcagcta aacttgctga
    24841 ttactaccgt tcgcttgact tgtcaaactc gtaatgtgaa taacgaagct atttgcagct
    24901 gatcgttctc tctttcttag taagagcaat caaacagctg actgaataat gaaaggaaga
    24961 ctgtatcgtg aaagaaaatc aagaagaact agataaagaa atgacagatg ctcagccaga
    25021 accggaaatc gatgtcgaag ctgcagaaga ttcgggtatt tcagaagctg aagcggaaga
    25081 attcgaaaca gcgaaattaa aagctgagtt agaagaaatg gaagataaat acttgcgggc
    25141 tcgtgctgaa atcgcaaata tggcaaatcg aggaaaaaat gagcgtgagc aattacaaaa
    25201 ataccgttca caagatttag ccaaaaaatt acttccatca attgacaacc tggaacgtgc
    25261 attagccaca gaagtgtcag atgatcaagg ggcaggtttg aaaaaaggcg tggaaatggt
    25321 cttggaaagt ttgcgtaacg cactggaaga agaaggaatt gaaaaaatcc ctgctaaagg
    25381 agaagccttt gatcctaatc ttcatcaagc agtacaaact gttccagcga ctgaagatac
    25441 accagccgat acgattgtag aagtactaca agaaggctac aaattacatg atcgcgtgtt
    25501 aagaccaacc atggtcattg ttgcacaata attgtgcgga tataaaactt acactttcaa
    25561 ttaaagaagg agacgttaat tatgagtaaa attatcggta ttgacttagg tacgactaac
    25621 tctgcagtag cagtattgga aggaaacgaa gcaaaaatca tcgctaaccc agaaggaaac
    25681 cgtacaacac cttctgttgt atcattcaaa aatggagaaa tccaagtagg ggaagttgca
    25741 aaacgtcaag ctgtgacaaa cccaaatacg atttcatcaa tcaaacgcca tatcggtgaa
    25801 gcaggttaca aagtagatgt agaaggtaaa tcatatacac cacaagaaat ctcagcaatg
    25861 atccttcaat atatcaaagg attcgcagaa gactatttag gtgaaaaagt cgaaaaagca
    25921 gttatcactg tgccagctta ctttaatgat gcacaacgtc aagcaacaaa agatgctggt
    25981 aagatcgctg gtctagaagt agaacgtatc gtcaatgaac caactgcagc tgctcttgcc
    26041 tatggtttag ataaaacaga tcgcgacgaa aaaatcttag tattcgacct tggtggcggt
    26101 acttttgacg tatctatcct tgaactagga gacggtgtct ttgatgtatt gtcaacagct
    26161 ggcgacaacc atctaggtgg ggacgacttt gataacaaaa tcatcgacta catggtagca
    26221 gaattcaaaa aagaaaacag cattgacttg tctcaagaca aaatggcttt acaacgcttg
    26281 aaagacgctg ctgaaaaagc gaaaaaagat ttatctggcg tatcaagcac acaaatcagc
    26341 ttgccattta tcacagcagg agaatctgga ccattgcatt tggaaatgac attgacacgt
    26401 gcaaaatttg atgaattaac agctgactta gtagaacgta caaaagtacc agtacgtcaa
    26461 gcgctaaaag atgcaggttt atcacaatca gaaatcgacg aagttatttt agtcggtgga
    26521 tctactcgta tccctgcagt tgtagaagca gtacgtaaag aaacaggaaa agaaccaaac
    26581 aaatcagtta accctgatga agtagttgct atgggtgctg ctatccaagg tggcgtgatc
    26641 actggtgatg tgaaagatgt tgttttactt gacgttacac cattgtcatt aggtatcgaa
    26701 acaatgggtg gagtgttcac taaattgatt gaccgcaata caacgattcc aacaagtaaa
    26761 tcacaagtat tctcaactgc ggcagataat caaccagcag tagacatcca tgtattacaa
    26821 ggtgaacgcc caatggctgc tgacaacaaa actctaggaa gattccaatt gacagatatt
    26881 ccagcagctc ctcgtggtat tccacaaatc gaagtaacat tcgatattga taaaaacggg
    26941 attgtaaatg tatctgcgaa agatctaggt acacaaaaag aacaaaaaat cacgatcaaa
    27001 tcttcttcag gtctaacaga cgaagaaatc gaacgtatgg taaaagatgc agaagcaaat
    27061 gcagaagcag ataaagctcg taaagaggaa gttgacctac gtaatgatgt agatgcattg
    27121 ctattctctg tggacaaaac attgaaagaa ttagaaggca aagtggacga agaagaagtg
    27181 aaaaaagcag aaacagctcg cgatgaattg aaagccgctg ttgaagcaaa caacatcgaa
    27241 gaaatgaaaa ctaaacgcga tgcattgaac gaaatcgttc aaaacttgac tgttaaacta
    27301 tacgaacaag cggcacaaca acaagctcaa gaaaacccag aagcagctca aggcggagca
    27361 gatgatgtcg ttgatgctga ttttgaagaa gtcgatggcg acgataaata atcagttcac
    27421 tgaatttcga gagaaggcca aagttgctac tttggctttt tcttttgaaa aatagtttga
    27481 agtatcggtt tttgtttcaa acaaaatatg atatgataac aagcgacgtg aaaatgatga
    27541 gaaccaatag gaggaaagcc tatggcaaca aaacgtgatt attatgaagt cttagggctc
    27601 tcaaaaggag catcagaaga tgaaataaag aaagcttatc gtaagctttc gaaaaaatac
    27661 catcctgaca tcaataaaga acctgatgcg gaagaaaaat tcaaagaagt atcagaagca
    27721 tatgagattt taagtgaccc gcaaaaacgc gctgcatatg accaatacgg gcatgcaggc
    27781 acagatccaa attacggtgc tggtggagct ggtggcggat ttggtggatt cggcggcttc
    27841 tctggtggcg gcttcggtgg ttttgaagat atcttcgact ctttctttgg aggaggcggt
    27901 cggtcagtcg atccaaatgc gcctcgtcaa ggtgctgatt tgcaatatac ggtcgacttg
    27961 tcttttgaag aagcgatttt tggtgtagaa aaagaaatca agtataatcg ggaagaaatc
    28021 tgtcatactt gtggtgggaa cggtgcaaaa ccaggcacac aaccaactac ttgtcataaa
    28081 tgtcatggtg caggtacgat taatgtagaa cgccaaacac cacttggacg agtgatgagc
    28141 cgtcaaactt gtgatgtttg tcatgggaca gggaaagaaa tcaaagaacc ttgtccaacc
    28201 tgtcatggct caggacatga gaagaaagca cattcagtta aagtgaatgt accagctggt
    28261 gtagaagaag gacaacaaat gcgtttagct ggtcaaggag aagctggaga aaacggcgga
    28321 ccatttggtg atttgtatgt ggtcttccgt gtagaagaaa gtgatatctt tgatcgtgaa
    28381 ggttctgaaa tttactatga attgccttta agttttgtac aagcagcttt gggggatgaa
    28441 gtccaagtac caactgtcca tggagatgtg aaattgaaga tccctgctgg aacacagaca
    28501 ggtacgaact tccgtttacg tggaaaaggc gctccgaagt tacgtggtgg tgcaacaggc
    28561 gaccaacatg tcaaagtaaa actgatcaca ccgaaaaatc taaatgaaca acaaagagaa
    28621 gcattacgtg cattcgctga agctggcggc atcaaagttg aagaacagca agaagacggt
    28681 ttcttcgata agtttaaaga tgcttttggc gggaaaaagc ggaagtagtt tttctagtaa
    28741 aaacgctaag tcattaataa ttaaaaacca gacgaacaat catatgttcg cctggttttt
    28801 ttgtagttgt catgtttgta ccaacaaaaa agccagcttt agaatatgat aatcgtcata
    28861 gtttctaggg gtataaccag tgagagaatg gaacttgttc aatcgatatt gcaaggtgtt
    28921 tttatgaata aataattctt ctgagcaatt tttgatgctt ccgttatttt tactgaagca
    28981 tgccaaagtc ttcttgaaca aatgtacttc ttcttctgtc aggcttttca aaatacgttt
    29041 tacatataat gttcgttgat ctgacgggat tgctggtaaa acgatcccga ggtctaaatc
    29101 ttcaaaaaag cggatctcgt tcacagattg atggaaagct atccattcgc aaacttgttt
    29161 ggcatgaagg aaagattgcg gtgtctcttg ctctgtataa caaagcgacc caattccaaa
    29221 gtttagctgt aactgataca ttttattaaa ctttgtctgg attttatcaa gcaatgatag
    29281 caatgaggct ctggaaatcc gattgactag gataatgatt tgttgtctat gtacagtgag
    29341 caaagcctgt ccgtaataag agaagaccct ttcgagcaac tccaataaag gattgatccg
    29401 ttcttgacac aattgctgat tgtcagaaag ttgtcccaca actacataat atggagaaga
    29461 aaaatcaagc tcaattaagt gagggtggta tcgactatgt acttgatatc atcaatgaac
    29521 cgatggtact ttcttatgcg atggaacagg tagagcgatt gcttgtttgt gcaggaaaac
    29581 aagcgatgcg gctgatacga ttaggtgaga aaataagaag ataaaaatac acggtccctt
    29641 catggcgacc gtgcattttt ggtttttatt aaatatttaa tactttattc aagaaatctt
    29701 ttgtccgttc attttgcgga ttttcaaaga tttgttgagg cgttccatct tctaaaaagt
    29761 ttccgtcgtc aatgaacatg acgcgattgg ccacttcttt agcgaacccc atttcgtgcg
    29821 taacgataac catcgtcata ccttgttctg ctaacttttt catgacgttc aagacatcac
    29881 cgaccatttc aggatcgagt gcagaagtag gctcatcaaa aagcatgatg tcagggttca
    29941 tcgctagagc acgagcaata gccacacgct gtttttgtcc accagaaagc atttcaggat
    30001 acatatcttt tttatcttct agaccaactg tctgcagtaa tttgattgct tttttctctg
    30061 cttcttctct agattctttc ttcaggtcca tcggtgctaa aatgatgttt tccaaaatag
    30121 aaagatgagg gaataggtta aagtgttgga ataccattcc gatatgttgt ctcaccaagt
    30181 tgatatctgt gcttttatcc atcaagtggg cgccgtcaat aataatttca ccgtcagaag
    30241 gttcttctaa acgattcaag caacgcaaga atgtactttt tcctgaacct gaagggccaa
    30301 tgatacagac gacatctcct tcgttgatgg atacattgat gtcgtttaat actgtgttat
    30361 cgccgtattt tttgactaaa tgctcaacta agattttttc tgccatctta cttcaccttc
    30421 ttttctaaaa cttttgctaa ttttgtcaat gctgtgatca aaatcaagta catgatcgca
    30481 atgatcaagt aaacatacgt actttgtgtt gtacgtgcaa caatgatctt accagtttgc
    30541 agcaattcga ctacaccgat tgcggaaatg atcgttgtgt cttttaatga gataacgaac
    30601 tgattgacga atgatgggat catgatgcgt atcgcttgcg gcaaaatgat tttttgcatt
    30661 gtccgattat aagaaagacc taaacttctg gaagcttcca tttgtccgac aggaacggcg
    30721 ttgatcccgc ctcgaacaat ctctgcgata taagcacttg cgttaagagt caaggtgata
    30781 acaccagcaa ggaagtcagg aatcgtaaat ccaacgatac caggcaaccc aaagaaaata
    30841 aagaacgcaa gaaccatcat tggaattcct cggatgatat cgacataaat actagcaatt
    30901 gtgcgaagag cgcgtattgg tgctacactg aataatccaa aaatcacacc gattactata
    30961 gccaaagcaa aggagatcaa agttaggaga attgttctcc aaagtccttt caacaatgct
    31021 tgatagttgt tttggataag tccaagaaat gttgattcat cagcagtgga agactcactg
    31081 gaagtttctg aaccatccgc tacatattct ttaataatct tatcgtattc gcctgttctt
    31141 tttaattctt tcaatccttc attgaacata ttaagaagct caggattttg tcctttttta
    31201 acggcaaatg catattttcc gccagattct tttttgatcg gtgtttccaa ttcttgtcct
    31261 tgtttgatcg cataaccgat taccggataa tcatccatca ttgcatcgat tgcgccaact
    31321 tttaacccgt cgtacaattg atcagcagca tcaaaatatt tgatagaata gccatattca
    31381 gattcatggt cgcttaaaaa ttcagcactt tcggtaccaa cttttgctcc gactgttttt
    31441 cctttcaaat cttcataaga cttgatcgaa gtatctcctt ttttgacagc taattggatc
    31501 ccgctatcaa agtaagaatc agaaaaatca tagcttttct ttcgttcatc tgttacagtc
    31561 attccggcaa tcattccgtc tgcttgtcct gattccaaag cttgcaaagc agcagagaaa
    31621 ccacggtagt ccattcggat gttaaatcct tgcagtttgg cgatgttttc catcaatttt
    31681 acatcgatgc cttcgtactc gccctttgcg ttttgaaatt caaatggagc aaaagcagag
    31741 tcactggcaa ttacgtatac gtcttttttg ggctctattt tttgcattgt ctcgcttgtg
    31801 cttgactctg ccgttgtagt gttgtcagct tgtgcaacat gaccaaacgc aagtgtcaca
    31861 agtcctgtca ttaagaaaac aaatgagtga aataaatgct ttcttttcat aatcaacctc
    31921 ctaaatttcc aatattttat tattataggc gaaaagtgct gaatcagaca agactgtaag
    31981 ctcgaaaaaa tgaaaaaaat gcgagtttct aacattttat gttataaaac ataacatgta
    32041 taataagata aaaaagtggc gaaagtatgt tcggtgtggt ataatttttt agtaaggaat
    32101 gcctttgctt tccttttctt tttattggtc gtaaaatgaa aaggaatgaa tgaaaaggag
    32161 gacgaagaat gattgagaga gatacctccc gacactttga gcttgtctcg aaataccaac
    32221 cggctggtga tcagcctgaa gcgattaacc aattagtgga tggcgtagtc ggcgggaaaa
    32281 aagcacaaat cttattaggt gcgactggaa cagggaaaac atatacgatt tccaatctta
    32341 ttgagaaagt gaataaacca acactgatta ttgcccataa caaaacattg gctggtcagc
    32401 tgtacgggga attcaaggaa tttttcccta acaatgctgt tgaatatttt gtttcttatt
    32461 atgattatta tcagcctgaa gcttatgtgc cttcaagcga tacgtatatc gaaaaagatt
    32521 caagtgtaaa tgatgagatc gacaaattac gacattcggc tactagttca ttattagaaa
    32581 gaaatgatgt gatcgtcatt gcatccgttt catgtatttt tggattaggc tcgccttttg
    32641 agtaccaaaa acaagtagtt tcgattcgac agggagcaga actagatcgc aatcagttga
    32701 ttcgtgactt agtcagtatc caattcgaaa gaaatgatat agattttcag cgcggtcgtt
    32761 ttcgagtgcg cggtgatgtc gtggagattt ttccggcttc aagagatgaa cgtgccttac
    32821 gtgtggagtt ttttggagat gaggtcgaac gtatccgaga agtcaatgca ctgacaggtg
    32881 aagttttagg agaaacggaa cacgtagcaa tcttcccggc gactcacttt gtgacgaatg
    32941 atgaacatat ggagcatgcc gtagcgaata tcaaagcgga attagaacag cgtttaactg
    33001 tcttgcgaaa tgaaaacaaa cttctggaag ctcaacgttt agaacagcga accaattacg
    33061 atattgaaat gatgttagaa atgggctaca cgtcgggaat tgaaaattat tctcggcata
    33121 tggacggacg taaagaaggt gaaccgcctt atacgctatt ggatttcttt cctgaagatt
    33181 ttttgatcgt ggcggacgaa tcgcacgtaa ccatgcctca aatcagagga atgtataatg
    33241 gtgaccgagc gagaaaacag atgctagtag attacggttt ccgtttgcca tctgctttag
    33301 acaatcggcc acttcggtta gaagagtttg aaaaacatgt caatcagatc atttatgtct
    33361 ctgcgacgcc aggaccatat gaacatgaac aaacagatac cgttatccaa caaatcatcc
    33421 gtccgacagg gctgcttgac ccagtgatcg aagttcgtcc aatcatggga caaatcgatg
    33481 atctagtagg cgaaataaat gaacgagtcg aaaaagacca gcgggtgttt gtaacgacat
    33541 tgacgaaaaa aatggcagaa gacctcacag attatttcaa agaattaggg atcaaagtca
    33601 aatatttgca tagtgatatc aaaacgctgg aacgaacaga aatcattcga gatcttcgat
    33661 taggtgaatt tgatgtgtta gttggaatca atttgcttcg tgaaggatta gacgtacctg
    33721 aagtttccct tgttgctatc ttggatgcgg ataaagaagg ctttttacgt agtgaacgtt
    33781 ccttagtcca aacgattgga cgagctgctc ggaatgaaga aggtaaagta atcatgtacg
    33841 cagacaaagt aacagattct atgcgtctag cgatggatga aacgtcaaga cgtcgtacga
    33901 ttcagcagaa gtacaatgaa gaacatggga tcgttccaaa aacgatcatt aaagaaatcc
    33961 gagatttgat ttctattacg aaagaatcgg aagatgatac aaaagaagcg gtacaagtct
    34021 cgtacgaaga aatgacgaag gaagaaaaag acacgttatt gatgaaatta gaaaaagaaa
    34081 tgaaagatgc ggcaaaagct ttggattttg aaacagccgc gaatgtgcga gatatgattt
    34141 tagaattaaa agcttcaaag taggaggaca acatggctaa cgataaaatt acgattcatg
    34201 gtgcacgtgc ccataacttg aaaaatatag atgtaacgat tccacgagat aaattcgtgg
    34261 tcgttacagg tttgtccggt tctggaaaaa gttccctagc atttgatacg ctgtacgctg
    34321 aagggcagcg gagatacgta gagagccttt ctgcttatgc tcgtcagttt ttaggacaaa
    34381 tggataagcc ggacgtagat agcatcgacg gattgagtcc ggcgatttct attgatcaga
    34441 aaacaacaag taaaaatcct cggtcgacag taggtactgt gacggaaatc aatgactatt
    34501 tacgcttgtt gtttgcacgt gtaggacatc cgatttgtcc caacgatcat atcgagatta
    34561 ccagtcaatc agtagatcaa atggcagatc aagtaatggc tttgcctgag cgcacaaaga
    34621 tccaagtgtt ggcaccgatc gtggtaaaga aaaaaggaca acataaaaaa atattcgaac
    34681 gaatccaaaa agagggatac gtccgcgttc gagtcgatgg tgagatctat gatttaagtg
    34741 aagtgcctga gctggagaaa aacaaaaaac atgatatcgc gatcgtcatc gaccggatca
    34801 ttgtgaaaga agggattcgt tctcgcctat ttgattcttt agaggcggcc ctgcgattag
    34861 cagacggcta tgctctggtt gacgtgatcg gtgaagaaga aatgttgttt agcgaacact
    34921 atgcctgtcc ttattgcgga tttactgttg gcgaactaga accaagactg ttctcattca
    34981 atgcgccttt tggagcttgt ccagactgtg atggtttagg tgtcaaatta gaagtcgatc
    35041 aagatttagt gattccagat agaacgaaga cacttagtca aggtgctatc gttccatgga
    35101 atccaatcag ctctcagtat tatcctcaaa tgttagcgca ggcttgtgaa agtttcggta
    35161 tcgatttaga tacaccattc gaagaattac cggaagagca tcaggagatc atcttgaatg
    35221 ggacagatga tcttttccat ttccattatg aaaatgattt tggtggcgtt cgcgatgtag
    35281 aaacgacttt cgaaggggta ttgaagaata tcgagcgtcg ttatcatgat acgaacagtg
    35341 atttcacgcg tgagcaaatg cgtctttata tgacagaatt aacttgtcag acatgtaaag
    35401 gttatcgatt gaatccccaa gctctatctg ttcaaatcaa tggaacgaat atcgggcaaa
    35461 caaatgagtt gtctattcaa aaagcagtag atttcttctc aaacttaacg ttatctgaac
    35521 aagagaaagt aattgccaaa ccgattttaa aagaagtaaa tgacagactt tcattcttgg
    35581 aaaatgtggg actagactat ctaactttga gtcgcgcttc cggaacatta tctgggggag
    35641 aagcgcagcg aatcagattg gctacacaaa ttggatcgaa tctttctgga gttttgtata
    35701 ttttagatga accatcgatc ggattgcatc aacgcgacaa cgatcgactg attggctcat
    35761 taaagaaaat gcgtgatctt ggcaacaccc tcgttgtagt cgaacatgat gaagatacga
    35821 tgtgggcagc agattatttg attgacgtcg gacctggggc cggagaacaa ggcggacaaa
    35881 tcgtggctgc aggcactcct gaagaagtag ctaatgatga aaattctttg acagggaaat
    35941 atctttcagg gaaaaaatca atccctgtac caaaagaacg ccgtaaaggt aatgggaaag
    36001 caatcaagat cactggtgct tcagaaaaca atctgaaaaa tattagtgtt gaatttccat
    36061 taggagaatt tgtagcagtc acaggtgtgt ctggttctgg aaagagtaca ttggtcaata
    36121 gtatcttaaa gaaatcgtta gcgcaaaaat taaataagaa ttctgctaag ccaggtaaat
    36181 tcaagacaat ttccggctac gaaagtatcg aaaagatcat cgatatcgat caaagcccaa
    36241 tcggccggac gccgagaagt aatccagcga cttatacaag tgtatttgat gatatccgtg
    36301 ggttatttgc tcaaacgaac gaggcaaaaa tgcggggtta taagaaaggg cgttttagtt
    36361 tcaacgtaaa aggcggtcgt tgtgaagctt gtcgcgggga tggaattatt aagatcgaaa
    36421 tgcacttttt gcctgatgtc tatgttcctt gtgaagtatg tcatggtaaa cgatataatt
    36481 ctgaaacatt agaagtgcat tacaaaggaa aaagcattgc tgatattttg gaaatgacag
    36541 tagaggatgc tgtagaattc ttcaagcaca ttccaaagat tcatcgcaaa ctgcaaacga
    36601 ttgttgatgt tggcttaggt tatgtgacga tggggcaacc agcaacgaca ttgtccggtg
    36661 gtgaggcaca acggatgaaa cttgccagtg aattgcacaa aatctctaat ggaaagaatt
    36721 tctatatact agatgaacca acgacaggac ttcatagcga tgacatcgcc cgcttgttgc
    36781 atgtattaca aagattagta gatgctggta acacagtttt agtgattgaa cacaatctag
    36841 atgtaatcaa aacagcagat tatatcattg atttaggacc agaaggtgga gaaggtggag
    36901 gaacgatcct tgcgactgga acaccagaag aaatcattaa cgtaaaagaa agttatacag
    36961 gtcactattt gaaaaaaata atggtataaa gaggatagat agctgagata gttaaaaaaa
    37021 cataaaaaaa tgaatttttg cttgttttat taatatcagt gttctagaat cattacatgg
    37081 tagttctttc tacactgatt ggtatagata aaaacttcct ataagttcaa tccgttcaaa
    37141 aaagaattga gcaatcggag gactttcctt tgattgcttt tttctttatg gtatgatatt
    37201 ccttgtgtag ttggaaaaga aaaacaagag attatgagta agtgagagat aatgatgaac
    37261 agtattgaaa atgaagaatt tatccctata ttattaggaa gcgacatgaa cgtttatggt
    37321 atggcacgtt cttttaatga agcatacggc aaaatctgcc aagcatatgc ttcggatcag
    37381 ttagccccta cccgctacag taaaattgtc aatgtagaag ttattccagg atttgataaa
    37441 gaccctgtat ttatcgagac gatgcttcgt ttggcaaaag aaagatattc tgataagagt
    37501 aaaaaatatc ttttgattgc ttgtggtgat ggatatgcag aattgatctc ccaacataaa
    37561 caagagctgt cagaatattt tatctgtcca tatattgatt attctttatt tgaaaggctg
    37621 atcaataaag taagctttta tgaagtttgt gaagaatatg atcttccgta tcctaaaaca
    37681 ttgatcgtca gagaagaaat gttagtaaat ggacatttgg aacaggaatt gccttttgaa
    37741 ttcccagttg ctttgaaacc tgcaaacagt gtggagtatc tttctgtcca atttgaagga
    37801 agaaaaaaag cttttatttt agagactaga gaagagttcg atttaatttt aggccggata
    37861 tacgaagccg gttataaaag tgaaatgatt gtacaagatt ttatcccggg tgatgatagt
    37921 aatatgcgtg tgctaaatgc gtatgtagat gaagatcatc aagttcggat gatgtgcctt
    37981 ggtcatccac tattagaaga tcctacacca gcatcgattg gtaattacgt tgtgatcatg
    38041 ccagattata acgaaaaaat ctatcaaacc attaaggcat ttttggaaaa aatcgaatat
    38101 acaggctttg ccaatttcga tatgaagtat gatcctagag atggagaata taaattattt
    38161 gaaatcaatt tgagacaagg tcgtagcagt ttctttgtga cattgaacgg cttgaatctg
    38221 gctcgttttg tcacagaaga tcgagtgttc aacaaaccct ttgttgaaac gacctatgga
    38281 acgaatcaat cagataaagc aagattatgg atgggtgtgc ccaaaaaaat ctttttagaa
    38341 tatgctcggg aaaatgaaga caaaaaacta gctgagcaaa tgatcaaaga aaatcgttac
    38401 ggtactactg tattttatga aaaagaccga tcaatcaagc gctggttgtt gatgaaatat
    38461 atgttccata actatattcc aagattcaaa aagtattttc atgtgaaaga aggctagttc
    38521 atggagaatt ttttcagtat tttaggcgga atgggcacga tggcgacaga aagttttgtt
    38581 cgcttgatca accaccgaac gaaagctaca aaagatcaag aatatttgaa ttatgtctta
    38641 ttcaatcatg caacagttcc tgatcgtaca gcttatattt tagatcgatc agaagaaaat
    38701 ccaatgccgt ttctgctgga tgatattgag aaacaaaatt tattgcgacc aaacttcatt
    38761 gtgttgactt gtaacaccgc acactacttt tttgaagagt tacaagcggc aacggatatt
    38821 cctatcttgc atatgccaag agaagcagca aatgaacttg tccgtcagca tacgacaggg
    38881 agagtagcga ttctaggaac agaaggaagt atgaaagctg gaatctatga acgcgaagtc
    38941 aaaaatcttg gtttcgaaac agtgattcct gatactgcgc ttcaagaaaa aatcaattac
    39001 ctgatctatc atgagatcaa ggaatcggat tatttgaatc aagagctcta ttacgaaatc
    39061 ttagaggaag cggtagagcg cctaaactgt gaaaaagtca tcctaggttg cacagaatta
    39121 tctttgatgc atgaatttgc tgaagataat cattacccag tgatcgatgc tcaatctatt
    39181 ttagcggatc gaacgatcga acgtgcatta gctgaaagaa gcgaggcatt ggatacagca
    39241 tcggaaaagt aaaaaaattg gatttggggc aaatatccta aaagatattt ggtccaaatc
    39301 tttttgtaaa agaaaaagaa aactggtaat gatacgcccg ggatgatata attttattat
    39361 gcacaatgtg agaggggttc gtaaatatga cagataattt gcaattagtc atcataacag
    39421 gtatgagtgg tgcagggaaa acagtagcta tccaaagttt tgaagatatg ggctattttt
    39481 gtatcgataa tatgccgcct cgattgattc caaaattctg ggaattgatc aaagaatcag
    39541 gtaaagtcac aaaaatggct ttaggagtgg atttgcgttc tcgttccttc tttgaagaaa
    39601 tccaaaacat gctgatcgaa atcgaaaata cgaacttcat cgacacttct atcttatttt
    39661 tagatgcttc agacgaagaa ctagtggctc gctacaaaga aacaagacga gcacatccaa
    39721 tggcgatgga cggtttgatc actgaaggga tacgtaaaga acgggcgata ctagacgact
    39781 tgaaagccca agcttccgtg atcattgata cgacaacatt gacaccacga caattacgtg
    39841 aaaaaatcaa tgagtcattc aaatcaaagg gagaccaagg atttcggatc gaatttgtat
    39901 catttggttt taaatacggg ttgccgatcg attcggatat tgtgatggat gtgcgttttt
    39961 tgcccaaccc tcattatatc ccggaactaa gaccattgac cggaaaagat cagccagtct
    40021 atgattatgt gatgtccttt gatgaaacgc aatcattcta ccataaattt ttggatcttc
    40081 tggaaactgt attgcctgga tacattaaag aaggaaaaag cagcttgaca gttgcaatcg
    40141 gctgtacagg cggtcaacac cgttctgtgg cattgactga acgtttggca aatgctttag
    40201 ggaaaaacta taaagtcaat gtgacacatc gggacaagga taaaaggaaa gagacggtga
    40261 accggtcgtg aaaatgaaaa cctaccggat aagaaaacca aagatcgtag tggtcggcgg
    40321 tggcactggt ctgccagtta tcctgaaaag tttacgaaat caaggagcag atatcacagc
    40381 agtagtgact gttgcagatg atggtggaag cagcggtgca atcagagaat cgatcgctat
    40441 ggctcctcct ggtgacttga gaaatgtctt agtggcgtta tcggatatgc cacaattcta
    40501 tgaagatatt ttccaatacc gtttcaaaaa ggaagatcag tttttagcca atcatacgat
    40561 cggtaatctg atcattgccg cagtttccga gatgcgggga agcacttatg aggcgattca
    40621 attattagca aaaatgatgc atgtagatgg acatgtttat ccttcttcag aaactccttt
    40681 gaccttgcat gctgttttta aagacggaac gactgcagta ggagaatcta aaatcgcgat
    40741 caaccgtaaa accattgacc gtgtgtatgt ctgcaacaca aatgataaaa gtgaagccaa
    40801 agcggctcga aaagtcgttt cagcaattat ggacgccgac atggtcgttt tgggacccgg
    40861 aagtttattc accagtatcc ttccaaattt agtgatacca gaaatcggcg aagcaatgct
    40921 caagacaact gctgaaaccg tctatatctg taatatcatg acccaaaaag gggaaacgga
    40981 acatttcaca gatgccgatc atatacgtgt tttacacaag catttgaatc agccttttat
    41041 cgatacagta ttggtcaata cggaaaaagt gcctgaagat tatatggacc cagagatcta
    41101 tgatgagtat ctagtacaag tcgcacacga cttcaacgga ttgagaaatg aaggatgtcg
    41161 agtgatttcc accgactttt tagaattgaa agatggtggt gtcttccacg atggagacaa
    41221 agtagtagaa gaattgttcc gtttagtttt cggttcaaaa tattaagcaa tttattgttg
    41281 gagaaaggag gagaatagga tgtcatttgc tgcagatgtg aagaaagaac taactggttt
    41341 ggaagttcat cgagaacatg cgaaagcgga attagctgct ttgctgcgaa tgaacggctc
    41401 tttaggtatt gtgaaccagc agtttatttt gaacgtccaa acagaaaatg ctgcaattgc
    41461 cagacgtatc tattctcttt tgaaagatca ttatcaggta cgaagtgagc tactcgttcg
    41521 taaaaaaatg aaattaaaaa agaacaatgt ctatatcgtc cggttgaagc aaggcacaaa
    41581 agatgtgttg atggatcttg atatcatgga tggtatgatg ttcaatggac acgtttcgga
    41641 cgagattatg ggaaattcgc aaaaaatgcg ttcttactta cgtggtgctt ttatggcctc
    41701 aggttcagtc aataatccgg aaacgagtcg ttatcatttg gaaatatttt ctatttatga
    41761 acagcataac caagacattt gcgatatgtt aaattattac ggtctacatg ctcgaacgct
    41821 tgaacggcgc aatggctata tttcgtattt aaaaggagca gaaaaaattg ctgatttctt
    41881 aacattgatt ggtgcaacca actcaatgct ccgatttgaa gatgttcgaa tcgtacggga
    41941 tatgagaaat tcggtcaatc gtctagtcaa ttgtgagaca gcaaatctga acaagacgat
    42001 tgatgcggct tctaaacaaa tcgaaaacat cgaattgatc gaagcaaagg tcggtctaca
    42061 tgcccttcct gaaaaacttc aggaaatcgc agaacttcgg cttcaacatc cagaggtcag
    42121 cttgaaagaa ttaggggaaa tgattccctc aggtgcaata tcaaaatcgg gaattaatca
    42181 ccgaattcgc aaaataaatg aatttgcgga aaaactgcgt gaagaagcag tttaatccaa
    42241 agaaaaaact gatacatgaa gcaggagatg cgaatgtatc agtttttttt aaaagctata
    42301 cttgcttttc ttccgtcaaa ctataattcc aactttactg gagtaacata atgttgaaag
    42361 gcttctattg ttttttaata caatcgtata aaaagcgggg agacaactga atgaagattt
    42421 tagttttata cataaacttt tgcttaatat agaagtcctg atatagatag gatcaagtat
    42481 ttatctataa ctggagatta attaaaaact ggaaggaact gctcgatcaa ccttgagaac
    42541 tgtttttctt acttctggtc aagattctcg tggttggtgg ataaggatgg ttgataagtt
    42601 cattggatta gctagtcgaa aacaaccagg tgtaattaat gtagaagttt taacaagggg
    42661 atggagtgat ttattcagtg ataatcataa gttcataaat agtaattggg atgtatggtt
    42721 ggtatacgtt atacctgaac ttgaactatc aagatttggt ttagaatttg agaatcgatg
    42781 tttataaagg gagggcaaaa aatgtgcttt tttacaactt ttactatcat tatgattgca
    42841 gtacttttta tttttctaga tatagcaaag cgaaatacag catttttatt atatcgggtt
    42901 ttacttcgag caggtctcat aacatttata tcgatcgttg gattttttct attcacagtt
    42961 attgtattta tttggagaac tacagcacca ccattgccag agattacata tggagaattt
    43021 ccgtttagtc ttgaatatga aatagatgag gaaagaattt tgattgaaga tacggtgatt
    43081 gcagaattta taggaagttt tagagggaat gtgacaactc aacctagacg aagttggagt
    43141 ataaaacttt taaataatag tggagagttg aaagcatttc attatgaatt cttaataata
    43201 gaaagtgaag atgtaacaat cactttaagt agtggctctg ctggatattt tatgaatgat
    43261 ggtggaagca agccacagct cacagtccgt gatcgtattg caggttttat gcatttttct
    43321 cactatgact tagaagaagc tcgtaaaata cttgcagaat atgggatcac attaatcaat
    43381 tgggaatatg cgccaccgat aagaaatttt ttcaatgatt attattagtc ttataaaaaa
    43441 cagaatgtaa aatttatgtg cgcgagtatt tagttttcca ttttttgttt gatagatata
    43501 tagcattgtt gaagcatggg atagtggtgc caattttatc aatgaggttg gtcaggcagt
    43561 taacataatt ggtgatgcta taaatccatt taattggaat tggaggaatt aggtgtggaa
    43621 acagtgagat tatggatatt catgaaaaat tttcgttcgg ctttgagata tgttattctg
    43681 gaatcaaaat caggttatta tctgattgac acagatcact atactttttg gggaggctac
    43741 ctttttccga tttttaattg gataatcccc cataaggtta tgaaaattaa cttgcctgca
    43801 gaagaaataa atagattaat actcaacaaa gatttacaaa ggaaaagaga gaaagaacat
    43861 tctaatgttg cttggatagg tccagcattt gcagtagtga cttcttcaat tgtcggtcct
    43921 atgctagaga gtatttatag tgatttttct attggaatac gttatttatt tgttacttta
    43981 agtatagctg ttcttttgtg cataaagggt tatgttagca agaagaataa agatatttta
    44041 acactaatcg gtgtaaacaa tttatctagt actaaaatta tactgtttcc tgaatctata
    44101 aaagaaggat caaggttgtt gataattttt ataatgctta tactgttttc tgttttattt
    44161 ggggtgatgt ttataga
//
LOCUS       DACCVH010000014        42816 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.014, whole genome shotgun sequence.
ACCESSION   DACCVH010000014 DACCVH010000000
VERSION     DACCVH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.014"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            72..317
                     /locus_tag="IVV98_000842"
     CDS             72..317
                     /locus_tag="IVV98_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806516.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            410..856
                     /locus_tag="IVV98_000843"
     CDS             410..856
                     /locus_tag="IVV98_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806517.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(915..1376)
                     /gene="mscL"
                     /locus_tag="IVV98_000844"
     CDS             complement(915..1376)
                     /gene="mscL"
                     /locus_tag="IVV98_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP7806518.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            1628..2896
                     /locus_tag="IVV98_000845"
     CDS             1628..2896
                     /locus_tag="IVV98_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP7806519.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2889..4175
                     /locus_tag="IVV98_000846"
     CDS             2889..4175
                     /locus_tag="IVV98_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP7806520.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            4953..5837
                     /locus_tag="IVV98_000847"
     CDS             4953..5837
                     /locus_tag="IVV98_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806521.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            6046..6624
                     /gene="pgsA"
                     /locus_tag="IVV98_000848"
     CDS             6046..6624
                     /gene="pgsA"
                     /locus_tag="IVV98_000848"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP7806522.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            6864..8105
                     /locus_tag="IVV98_000849"
     CDS             6864..8105
                     /locus_tag="IVV98_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP7806523.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            8214..9263
                     /gene="recA"
                     /locus_tag="IVV98_000850"
     CDS             8214..9263
                     /gene="recA"
                     /locus_tag="IVV98_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP7806524.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            9674..11230
                     /gene="rny"
                     /locus_tag="IVV98_000851"
     CDS             9674..11230
                     /gene="rny"
                     /locus_tag="IVV98_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP7806525.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(11309..12115)
                     /gene="proC"
                     /locus_tag="IVV98_000852"
     CDS             complement(11309..12115)
                     /gene="proC"
                     /locus_tag="IVV98_000852"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP7806526.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            12256..14829
                     /gene="mprF"
                     /locus_tag="IVV98_000853"
     CDS             12256..14829
                     /gene="mprF"
                     /locus_tag="IVV98_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP7806527.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            14983..15834
                     /locus_tag="IVV98_000854"
     CDS             14983..15834
                     /locus_tag="IVV98_000854"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP7806528.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            16079..17017
                     /locus_tag="IVV98_000855"
     CDS             16079..17017
                     /locus_tag="IVV98_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP7806529.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            17040..17720
                     /locus_tag="IVV98_000856"
     CDS             17040..17720
                     /locus_tag="IVV98_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7806530.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            17693..18517
                     /locus_tag="IVV98_000857"
     CDS             17693..18517
                     /locus_tag="IVV98_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7806531.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            18684..19502
                     /gene="purR"
                     /locus_tag="IVV98_000858"
     CDS             18684..19502
                     /gene="purR"
                     /locus_tag="IVV98_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP7806532.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            20005..21378
                     /gene="glmU"
                     /locus_tag="IVV98_000859"
     CDS             20005..21378
                     /gene="glmU"
                     /locus_tag="IVV98_000859"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP7806533.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            21472..22443
                     /locus_tag="IVV98_000860"
     CDS             21472..22443
                     /locus_tag="IVV98_000860"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP7806534.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      22449..22551
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22617..23186
                     /gene="thiT"
                     /locus_tag="IVV98_000861"
     CDS             22617..23186
                     /gene="thiT"
                     /locus_tag="IVV98_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP7806535.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(23267..24040)
                     /locus_tag="IVV98_000862"
     CDS             complement(23267..24040)
                     /locus_tag="IVV98_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806536.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            24307..26007
                     /locus_tag="IVV98_000863"
     CDS             24307..26007
                     /locus_tag="IVV98_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAP7806537.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            25977..26195
                     /locus_tag="IVV98_000864"
     CDS             25977..26195
                     /locus_tag="IVV98_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806538.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            26215..27105
                     /locus_tag="IVV98_000865"
     CDS             26215..27105
                     /locus_tag="IVV98_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP7806539.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            27123..27407
                     /locus_tag="IVV98_000866"
     CDS             27123..27407
                     /locus_tag="IVV98_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806540.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            27894..28508
                     /gene="gmk"
                     /locus_tag="IVV98_000867"
     CDS             27894..28508
                     /gene="gmk"
                     /locus_tag="IVV98_000867"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP7806541.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            28513..28818
                     /locus_tag="IVV98_000868"
     CDS             28513..28818
                     /locus_tag="IVV98_000868"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP7806542.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            29071..31479
                     /gene="priA"
                     /locus_tag="IVV98_000869"
     CDS             29071..31479
                     /gene="priA"
                     /locus_tag="IVV98_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP7806543.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            31494..31985
                     /gene="def"
                     /locus_tag="IVV98_000870"
     CDS             31494..31985
                     /gene="def"
                     /locus_tag="IVV98_000870"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP7806544.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            31978..32916
                     /locus_tag="IVV98_000871"
     CDS             31978..32916
                     /locus_tag="IVV98_000871"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP7806545.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            32916..34274
                     /gene="rsmB"
                     /locus_tag="IVV98_000872"
     CDS             32916..34274
                     /gene="rsmB"
                     /locus_tag="IVV98_000872"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP7806546.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            34287..35027
                     /locus_tag="IVV98_000873"
     CDS             34287..35027
                     /locus_tag="IVV98_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP7806547.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            35024..37093
                     /gene="pknB"
                     /locus_tag="IVV98_000874"
     CDS             35024..37093
                     /gene="pknB"
                     /locus_tag="IVV98_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP7806548.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            37258..38157
                     /gene="rsgA"
                     /locus_tag="IVV98_000875"
     CDS             37258..38157
                     /gene="rsgA"
                     /locus_tag="IVV98_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP7806549.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            38170..38820
                     /locus_tag="IVV98_000876"
     CDS             38170..38820
                     /locus_tag="IVV98_000876"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP7806550.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            38821..39459
                     /locus_tag="IVV98_000877"
     CDS             38821..39459
                     /locus_tag="IVV98_000877"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP7806551.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            39614..40468
                     /gene="mreC"
                     /locus_tag="IVV98_000878"
     CDS             39614..40468
                     /gene="mreC"
                     /locus_tag="IVV98_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP7806552.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            40472..40981
                     /gene="mreD"
                     /locus_tag="IVV98_000879"
     CDS             40472..40981
                     /gene="mreD"
                     /locus_tag="IVV98_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP7806553.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            41236..42810
                     /locus_tag="IVV98_000880"
     CDS             41236..42810
                     /locus_tag="IVV98_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806554.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT        14117 a         7637 c         9259 g        11803 t
ORIGIN      
        1 ttcttttttt tttatggtaa acttgaaaat tttaaaaata tgtggtatag ttgatagtag
       61 aggtgaactg tatgccaaca actttagctt caatcaagaa agatttagaa ggtcgtatcg
      121 gcagcccaat catgttggtt gctcagacag gaagaaagcg tcaaacagaa cgccgcggcg
      181 ttttaacaga aacctatcct tcagtattcg ttgttgattt ggatcctgaa gaaaattctt
      241 ttgaacgagt atcttacagc tattcagatg tacttactcg gacagttgag atcgaatttt
      301 taactgaagc agtttaaaaa gcaaacgagc ctgagattcg taaggttcgt ttgctttttt
      361 gtgtgcgaat cggtatgcta agaataaaaa agcagggggc gtttgcttag tggaatatca
      421 ggtaaagaaa tttgaagaat tgtcaacagc agagttttac gcgatcgtca aagaacgaat
      481 cgcagttttt gttgtggaac aacagtgtcc ttatcaagaa gttgatgaca ttgatggaga
      541 agcttggcat acgttttttc aagatactga tgggaagatc cttgcctaca cgcgagtata
      601 tgaagaagcg gagagtatcc attttggacg tgtccttgtt catcaggaca accgtaaaga
      661 tggtttagga agaaagattg ttcaagaaac gattaacatg atccagaaaa attttccaga
      721 aaaaccaatc gtgatcggcg cacaagaata cctacaagct ttttatgagt cgtttggatt
      781 caaggcaatc tcagatgtgt atttggaaga tgatattcca catatcgaca tgaaaaagga
      841 acaagtagca agttaagaat ctaaaaaaag aaagccgaca ctgaaaatcg gctttctttt
      901 ttttagattc tttattattt agaagtatcg gaaagatttg tttgctctac tggatgtgta
      961 ttgtcttctg ccacttgttt ggcaagaaga tcgcgtatgt cactaagata atcttctgca
     1021 gtaggagttt cttccacttc cacttgctct tctttggagc gtaaattctt cgcacggttt
     1081 gccgctttga caactaagaa taagacaaaa ccagtgatca gaaatgtaat gatagcacta
     1141 ataacgttac caaacgcaaa tgtgacgcct tttgtcggcg accagtcaag aattgaaagt
     1201 gctccttcta aatcagaagt acctgtgatc attgcgacaa accaacctat tagtggtgtg
     1261 atcaagcctt gcaccacttg gtttacgatg cttgtaaacg cactaccaat aacaacgccg
     1321 acagcaagat ccaagacatc tccacgcatg atgaactctt tgaattcttt gatcatgaat
     1381 gaccctccct tcttttattt gtctttagta tatcgaaaaa taaaaaataa aaaaacaata
     1441 tacgctttta gccgtctgtt tcttttgata aaaaacatct atgctatact ataaagtgta
     1501 acatcattta gaaaaaacgg cgaattgcct gaacttataa atttcaagca gaggaataag
     1561 taaaaaaggc aggttgaccc attaaaagag taagcgggca atcaactgtg aaaaggagca
     1621 tataaatatg gtgtatcaat tggcagaagg cgtgaatctt catgtcttac caacaaaaca
     1681 atacaaaacg atccggattt ttatccgttt tactgcgcgt ctgcaacaag aagtcatcac
     1741 gaaacgttca cttctcagca gcatgttgga aacaaatagt ttgaattatt cggatcagac
     1801 aaagttaagt gcgcaacttg cagagcttta tggcgcaagc tttggattat cagttagaaa
     1861 aaaaggaaat ttacattggc taaacgcagg gatcagtttt gtgaatggtg aatatgtcaa
     1921 tgatccaaac cttttttctc aagcggtaga ttttttaaaa gaggttttat tttatccaaa
     1981 tattaaaaat catcagtttg atcagttgac gtttgacttg gaaaagaaca atctgcgtct
     2041 atatttggaa agtttgaagg aagataaaca aacttttgct tcctatgcct tgcaagaact
     2101 ttattttgaa aacagcccgg aacaaaagat cccagggttg ggcgtagtcg aagatttgga
     2161 caagatcact gctagttcgc tagcgtccta ctatcaagaa atgatggcaa atgatcaaat
     2221 cgacattttt gttgtcggcg atgttgatcc ggacaaagca gctgaagcag ttgggcaatt
     2281 accatttgag tcgcgggaaa cagtttatcc agatctgttt tatacccaac ctcaagtgaa
     2341 tatcgtgaag gaacgacaag tacgtgagcc aatcgttcaa gcaaagctga acctagctta
     2401 tcagacaaat gtgtattacg atgaaccaga acgttttgcg ctaatggtct ttaacggttt
     2461 atttggcggt tttcctcact ctaaactttt catgaatgtc agagagaaag aaagtctagc
     2521 ttattatgcc tctagtagcg tggatacgtt ccgaggattc atgagtgtcc aaaccggtat
     2581 cgatgaaaag aaccgaaatc aagtacttca tctgattcac gagcaattag aaagtttgcg
     2641 aaatggtgaa ataacagagt tggaactgtc tcagacaaaa gcaatgctga gaaaccaata
     2701 tctgctttct ctagactctc cgcaagcggc aatcgaagct tcttttttgg acagctggct
     2761 gccggaaaca aaattatctg atgaagaatg gttgaaacgt atggagagcg taacgatcaa
     2821 agagatacaa caagtagctg agcaaatcga attgcaggca atcttctttt tagcaggagg
     2881 aaatgcaaat gaataaaaca gaatatgagc aaatcaatga aacactttat catgaagtac
     2941 tgccaaacgg tttgaccgtg tatttgttgc ctaaaaatga ctatcacaag acatatggtt
     3001 tgttcagtac gaattatggt tcgatcgata acgaatttat tccctatggt gaaaaagaaa
     3061 aggtgaaagt tccagatgga attgcccatt ttttagaaca taagttgttt gaaaaagaag
     3121 atggtgatgt ctttcaatta tttgggaaac aaggagcttc cgccaatgct ttcacaagtt
     3181 ttacgaaaac cagctatctg ttttctacga cggatcaggt agaaaagaat ctgacgactc
     3241 tgatcgattt tgtacaagca ccttacttca cagaagaaac tgtaaacaag gaaaaaggaa
     3301 tcatcggtca ggaaatccaa atgtatgaag acgaccctaa ctggcggatg ttttttggca
     3361 tactaaataa cttgtatcct acacacccat tgcatatcga tattgcgggc acggttgaaa
     3421 gtatcgacaa aatcacagct caagacttgt atacgtgcta tcggacgttt tatcagccaa
     3481 gcaatatggt tttatttgta gttggtaaga tggagcctga gaaattgatg aaacttattc
     3541 gggaaaacca agaagcaaaa aatttccctc caaagcaaga aattgtacgt tatttccctg
     3601 aaaacacaaa agaaatcatc aaacaaagtg cattggaagc agccattaca cgagataaat
     3661 ttgtacttgg tattaaagga ttagacacat tgccgcaaga aggaacagaa ctgttacgct
     3721 ataaaacagc aatcaatctg ttgttccaaa tgattttagg caatacttct cgaaactatc
     3781 tagcgatgta caatcaagga attatcgatg acagctttgg ttttgaattc agcttggatc
     3841 gtgaatttca ctttgcggac ttcagcggag atacggacga accagagaaa gcagcagaaa
     3901 aagtcaaaga aatcattctt ggattcgctg atgatccgga agtgtcagaa acaaatctcg
     3961 atttgctgaa gaagaaaatg cttggacaat atttccaatc attaaattcg atcgaatata
     4021 ttgccaatca atttacgcaa agtttatttg gcgatcgaac tttatttgat cttcctgaaa
     4081 tcatcgattc gatccaaatg aaagacgtac tggcagctgg ggaagcattt ataagtgaag
     4141 aggccttcag cgagttttac atgagaccaa aataaaccag tattttatga ggaaaagtct
     4201 taaatttcgt tttagacttg tagtaggaac ctcctccaaa atcagctttt atggtattct
     4261 tagttgtgtt ggaaaaatta gtgagaaaat aaaacaaatc atgctctctt ttaatcaact
     4321 tatattaaaa taaaatcaaa cgaagtaatc aaagaggttg tgacagaagt ggtcagcttc
     4381 aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgatat ttcggcttat
     4441 tgccgaagaa gctacttctg gaacaccgtg taccaagagg ttgtgaaaaa gctgccctgc
     4501 atcaagtaat aagaacagcc aagtaaaaac agcttcttaa tgtttttaac ttggttggac
     4561 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaatcagcgt
     4621 tttgacctga gtattagaga aacatacgga aaaatatctc cttatatttt gccggttttt
     4681 gagctaatac cgaggaacag ctgattgaac accgtttaag aaagaggtcg tgagcctgcc
     4741 gtttaactcc gagtcacaag gaacaagttc aaaaaacagc ttcttatatt tattggatat
     4801 tgtgacttgt gaccgaggag ttggcaggag aacaatgttt attcggaaaa aaggagctgt
     4861 gacatgactt ttgtcacagc acccaaacat aacgtctttc gttgcaacag cagatgcttc
     4921 ggagaatcaa acagactgga gaagatgaac gagtggcttt tgaaaccatc ggagaaaaat
     4981 tacggcaagc acgcctgaat aaaaaaatat ctttagatga attacagcag attacaaaaa
     5041 ttcaaaaacg ttatttggaa gcaatcgaca atgatgattt tgaccaattg cctggtaaat
     5101 tttacgtgcg ggcatttatt cggcaatacg ctgaagctgt aggagaagat ggagaccatt
     5161 tagtcgatgt ttttgatggg aaaagcaaat tgacaggatc ggtccctgaa cgtccgcagc
     5221 ctgaaacagt aagtacttct agaaaagcaa tgcatcagga agaatcgcat ccaagtcgct
     5281 tttggacaag tcttcctgtc attttattag gattggttgc tttggcgatt gtcgttgtcg
     5341 tgggctatat gacttggcaa gatcgtcaag ctgatccaat aatcggagac acagcttctt
     5401 cgcttaaagt agaaggatca gtcgaggagt cctcttcctc agagcaaagc acgcagacca
     5461 aagagtcttc tacagtagaa tcaacaacaa aatcaagtga agaaaagaaa atggcaatag
     5521 ctacaggaga agattctggc agtgccatcg cagtaaatat cacagacgct accaagcctg
     5581 taacccttga atttactgct gtcaatcgtg tatggttagg tgtgctagta gacaatgcct
     5641 atgtttatca agggacactg gcagcaaatg aaacacagag taccgtgtta ccggaaacag
     5701 caacaaatgc gaccatcacg attggtgcag caagcaatgc aacgatcaaa gcgaatggag
     5761 aatccgtacc agttaatcca ggggaaaaca atcagagtcc aaaaaatgtg aaccttactc
     5821 ttcaatacgc agaatgatcg tataaattag tttacgcatc tgtttacttg taggtataaa
     5881 aaagaaggat cgtgacaaat ctgtgtcgcg gtccttcttc gttaattcaa aaagatcaat
     5941 ttcaataaaa atactccttt gaataaattc atttggaaaa gtaaataata tcggtggaaa
     6001 cttcgctgat agtcacgtag aatagggaag aaaggagtcg atagtgtgaa tttaccaaat
     6061 aaattaactg tacttagaat ttgtatgatc ccgattttca ttttggttgt aggtttacct
     6121 ttagattggg gacaatttaa cgtaggagac accacactgg ctgtcacaca gctagtaggt
     6181 gcagttattt ttgctttagc tagtatcaca gactggttag atggaaaaat tgcccgtgcg
     6241 cgaggccttg tcactaattt tggcaagttt gcggacccgt tggcagataa aatgctagtt
     6301 atgactgctt ttatcatgtt ggttgaccaa ggaaaggccc ctggttgggt agtagcgatc
     6361 attgtctgtc gtgaattagc cgtcacaggc ttgcgtttac tacttgtcga acatggagaa
     6421 gtcatggctg cagcttggcc gggaaaagtc aagacggcta cacaaatggt tgctattatc
     6481 ttgctgttta tcaataatat cccattcagc ctgatcggta ttccagtaga tcaaatcatg
     6541 ctttatgctt gtctgatctt tactatctat tcaggtgtgg attacttcat caaaaacagc
     6601 ggtgtgttca aaggatcaat gtaagtatcg tttagtggag aggttgtgag cctgccgtct
     6661 aactctgagt cacaagggat aatttcaaaa aacagctttt catgttttat gtatattgtg
     6721 acttatgacc gaggttttgg caggagaaca ctgtttattt ggaacaagga gctgtgacaa
     6781 gatttttgtc acagctcctt gccctctttt taaataaaaa aatataaaaa tacagcgtat
     6841 actatataag ggagcgggaa gtaatgaaag cagaaataat agctgtcgga acagaacttt
     6901 tactaggaca agtcgtgaat acgaatgcca ctttcttgtc agaacagcta gctgatctag
     6961 gtatcgaagt ttattatcaa acagttgtag gagataatca gcagcgttta gaagagttga
     7021 ttgctctagc tgaaacaaga agtgaactca tactcttatg tggcggatta ggaccgacag
     7081 aagatgacct gacaaaagaa gcaactgcgg ctcacctcgg taagtctctc atacaaaata
     7141 cggaaggata caaaaaatta ttggcatatt ttgaaacaac ccatcgaaaa atgaccaaaa
     7201 acaatctgca acagtcccag attatcgaag gcggggttcc tctaccaaat cgtacagggc
     7261 ttgctttagg gactttttat caaacagata cacatgcgta tatccttctt cccggtccgc
     7321 ctaatgagtt gaaaccaatg tttgtggaac aagtacgtcc tttactagag gaacgttttc
     7381 cttctgaaga aaaactaatt tctaaagttt tgcgctttta tgggattggt gaatcgcgac
     7441 tggtcactga gctaaaagat ctgattgaga cacagatcaa tccaacgatc gcaccatatg
     7501 ccaaaccaaa tgaagtgaca ttacgactga cagtgaaaac aaatgatgtt caggcaggga
     7561 atcaagctct tttagcatta gaagaaaaaa tccaagaacg agtaggggaa tatttttatg
     7621 gatacggcga tgataattcg ctagcaaaag tcgtagtgga actactgaaa gaaaacaagc
     7681 agactgtaac agcagcggaa agtttgacag ccggcgcctt ccaagccgca ttaggcgaca
     7741 ttgctggtgt atctgaagta tttccaggcg gattcgttac ctactcgctc caaacaaaag
     7801 ctggttttct ggagattgat ccggagctat tagcagaata tggaacagtc agcaaagaat
     7861 gtgtggagca gatggccatt caagcacgtg agatagcaag aacagattac agtgtagctt
     7921 tcaccggagt ggctggaccg gacacgttag aaggtcaatc tgcaggaaca gtatggatcg
     7981 ctatttcatc taaagacggc gtggtttcgg aaaaatatca ctttgccaga gatcgtgctg
     8041 ctatcagata taatgcggtt atgcaaggat ttgatctttt gagaaaacag cttttaagaa
     8101 aatgataaat gcgaatattt gttcggtttt ttcttgcttt ttttcactaa aaaagatatg
     8161 ataaggataa tgaaatgttg ctctgatttg taaatataag gaggattatc gtattggcag
     8221 atgatcgtaa agcagcctta gatgctgcac tgaaaaaaat tgaaaagagc tatggtaaag
     8281 gctctattat gaaattgggc gaaaaaatcg accaacaaat ctctacaatt ccaagtggct
     8341 ctcttgcgtt agatgtcgct ttaggtgtcg gcggttaccc ccgtggacgt atcatcgaag
     8401 tatatggacc tgaaagttca ggtaaaacaa cagttgcact acacgctatt gcagaagtac
     8461 aaaaaaatgg cggaacggcc gctttcattg atgctgagca tgcgttagat ccgcaatatg
     8521 cacaaaaatt aggtgtgaat atcgatgaac tacttctttc acagcctgac acaggagaac
     8581 aaggtctaga gatcgctgat gctttagtat caagtggggc tgtagatatc gtagtagtcg
     8641 attcagttgc tgctttagtt ccacgagcag aaatcgacgg cgaaatgggt gactcacatg
     8701 tcgggttaca agcacgtttg atgtctcaag cattgcgtaa actctctggt tcgatcaaca
     8761 aaacaaaaac aatcgctatt ttcatcaacc aaatccgtga aaaagtaggc gtgatgtttg
     8821 ggaatccaga aatcactcct ggaggacgcg cattgaaatt ctacgcaacg atccgtttgg
     8881 aagtacgtcg tgcagaacaa ttgaaacaag gtacagatat tgttggtaac cgtacaaaga
     8941 tcaaagtcgt aaaaaacaaa gtagcacctc ctttcaaaat cgctgaagta gatgtcatgt
     9001 atggtttagg gatctcacaa gaaggagaac ttctagacat ggcagtagaa aaagacattg
     9061 ttgataaaag cggtgcttgg tattcttata aagaagatcg gattggtcaa ggacgggaaa
     9121 acgctaaaat ctatatggct aatcatcctg aaatgatggc agaagtttct gctctagtta
     9181 gagcagctta tggtattggt gaagaagtcg ctgtcccaga agatgaaaaa ggacaagaag
     9241 aattgccttt agtagaagaa taaaaattat gataaacaaa aacggctggt ctgaagagta
     9301 ggtactctcc ttgacctgcc gtttttttat tgaataaaga aatcgtgagt tatttaatta
     9361 tacgagtggg tacataaaat aaaaatatct gttcatctac aaagaataat ttaatagaaa
     9421 agtttctcaa tttaaaggtt tacctatatg aaactagtgt catttatttt aaaaaccatc
     9481 gtttaatgaa taagtagaaa gccgtttctt tgtttattta aagttgacac tacggggtac
     9541 aaacattaga ataaagttgt gcatgttttt tgtacacata tatgcgaaga tgcatattga
     9601 cgagtttaga ataatttatc atagaagctg tatagatgat aaaaatgaaa aagatagtat
     9661 ggaggtggat tttatggtat tcaacattct cctcgctatc atcggtttaa ttgtcggtct
     9721 tggtttaggg tttatggtcg caaagtcacg tcacgagaaa gaaatagctg gtgcacaatc
     9781 atcagctgct ggaatcatcg atagtgcaaa aaaagaagca gaaactctaa aaaaagaagc
     9841 attgttagaa gctaaggaag aaaatcagaa ataccgttct gaagttgaaa gtgagctgag
     9901 agaaagtaag ttagaattaa aatctcaaga gaatcgtttg attcaacgcg aacaaacgct
     9961 gaatcgtaaa gatgactcgt tagaaaaacg cgagaactca cttgaaagta aagaagaagc
    10021 acttagttca aaacagcaat taattgaaga gcgagaaaaa gacgttgaaa aaatgattga
    10081 agatcaacaa aaagaactag aaaaaattgc tggtttatca aaagaggacg cacgagatgt
    10141 catcatgaaa tcgactgaag aagagctgaa tcatgagtta actctaatgg taaaagaatc
    10201 tgaacagcgt gccaaagaag aagcagatcg caaagcgaaa aacttattat cattagcgat
    10261 tcaacgctgc gcagcagatc aagtttcaga aacgactgtt tcagtcgtta cccttccgaa
    10321 tgatgaaatg aaaggtcgta tcattggacg agaaggtcgt aatattcgaa cgcttgagac
    10381 gctgactggt atcgatttaa tcatcgatga tacaccggaa gcagttgttc tttccggatt
    10441 cgatccaatc cgaagagaaa tcgcacggat gaccttggaa aaactgatac aagatggacg
    10501 aatccatcca gcgcgtatcg aagaaatggt cgagaaatct cgtaaagaaa tggatgaacg
    10561 tattcgcgaa tacggggaag aggcagcgtt tgaagtcggt gctcatacac ttcatccaga
    10621 tctaatcaag atcatcggac gtctgcgatt cagaactagt tatggacaaa acgtcttgaa
    10681 gcattcggtc gaggttgcaa aattagctgg tatcttagca gcagagcttg gcgaagatat
    10741 ccaattagca aaacgtgccg ggttgctcca tgatattggg aaagcacttg accatgagat
    10801 tgaaggatct cacgttgaga tcggtgcgga attagctgcc aagtacaaag aaaacccagt
    10861 agtaatcaac gcgatcgctt ctcatcatgg agatgtggaa gctacttctg ttatctctgt
    10921 ccttgtagct gcagcagatg cgctctcagc agcaagacct ggtgcgcgaa gtgaatcatt
    10981 agaaaactac atccgtcgtt taagaagtct ggaaaatatt tcgaacagct tcgccggtgt
    11041 agaatcaagt tacgcagttc aagctggacg cgaagttcgg gtaatggtca agccagaaga
    11101 aatctcggat ttagacgctg ttcgtttagt acgtgatatt cgtaaacgaa tcgaagaaga
    11161 actggattat cctggacaca tcaaagtaat cgttattcgg gaaactcgtg caactgatta
    11221 tgctaaataa taaaaaatac aaaagaagag ccgcggcaaa agccacagct cttctttttt
    11281 tgtaaggcac gaaaaaacat tgctatcatt attttttatt caacatctca agatctttct
    11341 cgatcgtcgt attgattcct ttgatgattg ctgggatgaa tcctgcttct tctaaggcaa
    11401 ctacacctgc aacagttgta ccgccaggag aagaaacttg gtctacaagt tcccatggat
    11461 ttttatcact tgaaaggaat ttttgacaag aacccataat tgcttttgca gcaatctcag
    11521 tggctgtctg tttggacaaa ccattcagta caccagtccg tcccatcgca tcgatcagca
    11581 tgtaaacgaa tgcgggtgag ctgccagcaa ggccaatgaa tgtactgaaa tctgattctg
    11641 ctaaaggata gacgctgccg attgcttcaa aaatcatcgt agcttgctga agctgttcct
    11701 ccgtggcagc ttcatttttg caaatcgcag aaacgcctgc tcctacgctg acattgacat
    11761 tcggcatcac acgtacgatg gaggcctgag gatcttcaag cgctgtttct aaatctatta
    11821 atgattttcc tgaagcaata gaaatgaata agactttctg gctatattct cttagttctt
    11881 ccaatacttt ttcaatgatt tttggtttca cggctaaaag aacgatatct gattgtgatg
    11941 caacttcctg attacttttg catgcatgga cgccagtttc agcagcaaat ttttgtgcat
    12001 tttcaaaatg tccactggaa acgaacacct cttctttcga gactgttcct ttttttaata
    12061 aaccatcaat aatagcttgt gccatattcc ctgtgccgat aaatcctact ttcatgttat
    12121 cctctccttt agcattagga tatctttctt tttctatcat cgcaagcaaa gaacaggtct
    12181 aaagtggaaa aattaaaata aataagataa cattggggta tgacacaaaa gtatacaagt
    12241 taggaatggg aaaatgtgaa aaataaacga tacttgatgc tgcaatggat aaaggaacat
    12301 agtctgattt taaaactgat ttttttcggc tccgtgttag tctttgtggc aaatcaagtc
    12361 gcaaatattg ctaatggcat gagttggcaa gatatttggc aaaggatggg acaacaaagc
    12421 cgcatgacga tcctgctcat gattctggct ggactgctgg gtgtcactcc gatgttgttg
    12481 tatgattggg tgacgatcag agtcttagaa aaacaaggaa aaccaaaaat ggaaagaaaa
    12541 gagtttcttc ttgctgcgtg ggtaacaaac acgatcaaca atctcgccgg ttttggtggt
    12601 gtggtaggag caagtctgcg ggctagtttt tatggaaagc agacaaatag aaaaatggtt
    12661 ttagccactg tatcaaaagt cgcactattt atgctgactg gtttgtctgt atggtcgttt
    12721 cttacattta ttgatgtctt ttttattcag tcagaaagta tttttcgaag ctattggatc
    12781 tggcttttcg gcggtagttt tttagcacca gtcattttct tttttgctta tctaaagaga
    12841 aagacattgt tcttcgagtt ttatccaaaa ggcttgcttg gtctgctact ggcatccttt
    12901 ggacaatgga cgggagccct tgcggtattt ttgatcatcg gcaagttgat gagaatagat
    12961 atttcgatgc tttcgatcta tcctatgttc atgattgcta cattgatagg aatgctgacg
    13021 atggtcccag gtggaatggg gacttttgac gttttgatga tcttaggaat gagtcaattg
    13081 tctgttcggc aagatgtagc agtagtttgg ctattatatt atcggttgtt ttattatgtt
    13141 ctacctttta tgacgggact tctattgttc atcacacata caggagtcaa aatcaatcga
    13201 tttttagata acattccgcg actgtttttc caaaaggttg cgcatatcgt gctcgtaagt
    13261 gctgtctatt ttgcggggat catgatggta cttctatcaa caatcactaa tctgtctgca
    13321 atcagtcggc tatttcaagt attattgccg ttctcattca attttttaga tcagacagtg
    13381 aatctattgg ttggcttttt attactcggc cttgctagag cactttcagt aaaagtcaaa
    13441 aaggcatttc tgcctacgat tgctttacta tcttttggta ttttaaatac aatcacacgt
    13501 acgttatctt ggcagttgat attggtatat gtcttgattc tgttagctgt gtggttatcc
    13561 agaaaagaat tttatcgaac aaaattcgtt tattcttggg gagctataat ctttgatgct
    13621 agcttgttcg gctttttgtt tatcgtttac gcaattgcag gctatcacag cggacgcttt
    13681 ttagtcggtc gaataacagg aaatcatttt attttgtttc cttcagatga tgtgtggttc
    13741 tcagggctta ttggtttggg catctcattg ctagctttag tggcgcttta tcaatattta
    13801 gctgaagata ctacgaagct tggcagtgag tacgaaaaag accgttttga ccgtttattg
    13861 gaaacatacg gaggcacagc tacaagccat cagcttcgct tgtcaggtta cagttatttt
    13921 tattaccaag aagacgacca agatcaagtc gtttttggtt atcagatcaa aggaaacaaa
    13981 tgctttgttt taggagatcc agttggcaat cctaaaatga tgcgggcagc aacgaatcag
    14041 tttatgaaac aagcagattg tttaggctat cagcttgcgt tttataagat atcagaaagc
    14101 tacgtagtga tgcttcatga attgggtttt cacttcacga aagtaggtga agcagggatt
    14161 gttgatctag caacagaaga cttgtctcgg ctgagtcagc aacttgaata tcaacgtttg
    14221 atgaaagaag gataccattt tacttggtac gatcaactgc cggaagaatt acatcaagct
    14281 gtaaatgaag tttcacaaaa atggcttcaa ggtgcacgag aaaaatactt ctctgtggga
    14341 cgatttgata aatcatatgt attatctagc ggtgtcggta ttgtccgtaa agatcaaaaa
    14401 gtcgttggct tcatcaccgc tcagccgatg acgaagaagc aggcgggata tgatttgttg
    14461 cgggtcttac ctaaagaatc tgaggaatta gctgactatc tgttagccaa tctgtttatt
    14521 gtatacgaga aaatgggcta ctcggaagcc aatctaggct tagctccatt agctaatgtt
    14581 ggagaaacag atttttcttt ctttcaagaa aaagtcatgc atatcgtata taattatggt
    14641 aattttttct attccttcca gtctgcttat gaaaagaaat taaaatatgt cgatcattgg
    14701 gaaggacgtt attttgctta taggaaagga agtaatttcg gatttgctac catgcagcta
    14761 ctcagtctga taggaaaaga aaaaggaaat gttccgagtt tggcagaaga agtgctcaca
    14821 gaattataag aatcactaga acttgtttgg attatgaaga gaaaattctg tgaaagctgt
    14881 tgaaacgatg acaaaatcaa ccactaggca gacataagct atacttttat ttttccctat
    14941 gatagaatac ttgcgactta gacttttcga atgggtgaga ggatggaatt gattgaaaaa
    15001 gcgccagcca agataaattt aggactggat gtattatata gacggcaaga tgggtatcat
    15061 gagttggaaa tggtgatgtc gagcgtagac ttggcagatc atctattttt tgaagaaata
    15121 acagaagaca aaatcattgt agaaacaaat aaagcatttt taccggtaga tgaacggaac
    15181 aatgtttatc aagctgcttt attgctaaaa aataaataca atatcaaaac cggtgtcaag
    15241 atctttgtta agaagaatat tccagtagca gctggattag gcggaggaag tacagactgt
    15301 gcagctgctc taagagggat caaccaatta tggaatctgg gctgttcgtt agaagaactg
    15361 gcagaaatcg gtttggaagt cggtacagat gttccttact gtgtctacgg aagtacggca
    15421 tttgtcggtg gcaaagggga agaaatccaa gtattacctt ctatgccaca gtgctgggtt
    15481 gtgttggtca aaccaagaat gagtgtctct acacgtacag tgtttagaga agtagatacg
    15541 caagccatcc aacatcaaga catccacgga cttgctgaag ccatccgaga gcaagattat
    15601 cagcagatga tcaaaaaaat gggaaacagt ttagaagata taacgggaaa gcggcatcca
    15661 gtcatccatc aaatcaaaga gcgtatgatc aagtacggag cagatgctgc attgatgagt
    15721 ggaagcggac caaccgtttt tgccttgtgt caacattatt caagagcgca gagagtatat
    15781 aatgggttaa aaggtttttg tgaggaagtt tatttagtac gaaccctgca ataaaatata
    15841 agaagtaaaa taggtgatga aaaactgagg aatcctaaaa tggtattctt cagtttttta
    15901 ttgtagtgaa atggctagat atgagcagca actcatccat tttacgattt aatcaagaat
    15961 atacatgctt aaatcagaaa ttgatggatt tctattgact gtgttttttt attttgatac
    16021 attagttcac gttaataaat cgtaaaattc cgatttgttc attgaaagga gcatataaat
    16081 gaaaaaatat cttttgacag ctacggtaat gataggtgct ttactgtttg cagcatgtgg
    16141 aaatacgaac aaggaagcag acaaaaaaga ggatttgacg atcgttacga ctttttatcc
    16201 gatgtatgat tttacaaaag agatcgtagg ggatgaagga aacgtgaaac ttttgatccc
    16261 tgctggaacg gagccgcatg atttcgaacc aagtgcaaaa gaaagagcag aaatttccga
    16321 tgcagatgtt ttcgtgtata atagttcaga catggaattt tttgtggatt cgttaaagga
    16381 ttcagtggat agcaaacaga ccttgatgat cgaagcagct aaaggaatcg accgtttaga
    16441 atcgcaagaa gcagacgaac atgaagaatc agaagaaggg catggtcatt cacatgaata
    16501 cgatccacat gtttggctcg atccggtatt agctataaaa gaagtcagaa cgattgctga
    16561 agaattaggc gaaaaatatc cagataaaaa ggaaactttt acgaagaatg ccgatgctta
    16621 tatcaaaaag cttgaagcac tggatcaaaa atactccgat gagctaaaag atgcaacaaa
    16681 ccgcacattt gtcactcagc atgctgcttt tgcttattta gcgaatcaat acgacttaaa
    16741 acaagtagcg atttcgggcg tttcaccaga tcaggaaccc acaccaagtc gcttagctga
    16801 gctaaaagaa tttgtgaaga aaaacaacat caaagtgatt tattttgaag aaaatgcctc
    16861 ttcgaaggta gctgagacat tgtcgaatga aacaggagtg aagctagaag tgttgaatcc
    16921 tttagaaagc ttgactaatg aacaaatcaa agcaggcgaa aattatattt ctgtcatgga
    16981 aaaaaatctg aaagctttaa aagaaagtat caattaagtt ttagaatgga ggttgtaagg
    17041 tgcgttatat cgaaatatct gatttgacct tttactatga tgatgaacct gtactagaag
    17101 atgtctctta tcatgtagat gcgggtgaat ttgtcatttt aactggagaa aatggagcag
    17161 ccaagtcaac cttggtgaaa gcatcgttag gattactgaa accttcaaaa ggaatgataa
    17221 agattgctga gaaaaatcaa gaaggaaaaa aattaagtat cggttatatt cctcaacaag
    17281 ttgcatcttt caatgcaggt tttcctagta cggtgatcga attagtccgt tcaggaagat
    17341 atccaagagg ccgctggttc aagcgtctct ctgaaaaaga tcatcaacat gtacagcgtg
    17401 ctttagaagc tgtagggatg tgggatatgc gaaatcggcg aataggtgaa ttgtctggcg
    17461 gacaaaagca gcgaatcagt ttagcgcgta tttttgctac tgaccctgac ttatttgttc
    17521 ttgatgaacc aacaacaggt atggatgaag aatccagaaa tgaattttat cgtcttctcc
    17581 gacatagtgc gcatgtccat gggaaatcag ttctaatgat cacccatgat catgaagata
    17641 tcaaacagta tgcggacaga cagatccgac tggtgagaaa ggaggattct caatggcgtt
    17701 gctttcatat gaattcatga gaagagcgtt tcttgccgct atcttcattg ccggaatcgc
    17761 cccgatgcta ggtgtgtttt tagtgatcag aagacaatcg ctgatggctg atacgctttc
    17821 tcatgtctct ttagcagggg tagcgttagg attctttttg aaccttaatc ctacacttac
    17881 gaccatgcta gtcgttgtat tagcagctgt gatattggag tatctgcgaa cgatctaccg
    17941 aacctattca gaaatctcca ttgccatttt aatggctggt ggtttggcgc tagcgttagt
    18001 attgatgaat ttgagcggag ggaattcagc aacaagtatc caatcctatc tgtttggttc
    18061 gatcgtgacc attacatggg agcaagtcat ctttttagga atcttattcg ttgccatcgg
    18121 tatattgttc tttttattca aacggccgat gtatgttctg acttttgatg aagataccgc
    18181 ccacgtggat gggctacccg ttcatttgat gtcgatgatg ttcaatgtga ttactggtgt
    18241 ggctattgct gtgatgatcc cgattgccgg tgcacttttg atatccgcaa tcatggttct
    18301 tcccgcagca atcggtatgc gattaggcaa aagcttcaat gtcgtgattg ctatcagtgt
    18361 ttgtgtagga tttctaggga tgctgtcagg actaactagc tcgttttatc tagatacacc
    18421 tccaggagca acaatcacat tagtctttat tgctttgttc ctgattgtaa atatcatcaa
    18481 acgaatattg gttgccttca gaagaaaaaa taactaaatt ataaagaaaa gaagccttat
    18541 aaaaacgaaa aattttttat aggcttcttt ttattttaat aaataccgaa ctattttctt
    18601 attttttcat aaaatgctcg aatttttgaa gaaaaactta tataatgtaa aacgataaaa
    18661 tttcttaaaa ggagttggaa taggtgaaag tacgtcgcag tgaacgtcta gttgacatga
    18721 cacagtattt attgaatcac ccgcatgaat tgatttcctt aacaagcttt gccgaacgtt
    18781 atgaatctgc taaatcttct atcagtgaag atttgggaat catcaagaaa acatttaaag
    18841 aacgagggta tggaaccttg gaaacaatcc cgggtgctgc aggtggtgta ttgttcatcc
    18901 ctgaaatttc atatgaagag gcgaaaaaat atattgaatc tctagcagaa cgtctatcag
    18961 aacaagaccg tctgcttcca ggaggatatg tttatctctc tgatttgtta ggagaacctg
    19021 aactgctgcg tcaagttgga agaatcattg cttctaaata ccttggtgaa aaaatcgatg
    19081 ctgtaatgac tgtagccaca aaaggcgtac ctattgccca agctgtgtcc tattatctga
    19141 atgcgccatt cgttattgta cgccgggact caaaaataac agaaggatca acagtaagtg
    19201 tcaactatgt gtctggatct tctgaaagaa ttgaaaagat ggaactgtct aagagaagtt
    19261 tgaaacgtgg ttcacgtgtc cttgtagtgg atgatttcat gaaaggcggc ggaacagtca
    19321 acggaatgaa gagcttgatt gaagaattcg aatcagaact tgttggcatc actgtatttg
    19381 ccgaatcaaa attcaacggt catcgcgcca tcgatgatta tacgtcactg ctttatgtca
    19441 aagatgtaga tactcaaacg aaaaatatta cggttgtgcc aggaaattat ttttcagaat
    19501 aagaggttgt gaaaaagccg cttagtttcg agtagtaaga aaaattttgt gaaaatggct
    19561 ttccacattt tttcataaat ttggcttaat accgagaaac tggcttttga acaccgttta
    19621 tctagaggtt gtgaaatcag cgtcctgtcc tgagtattag ctcaataaac ggaaaaattg
    19681 ctcctcatat tttgccgttt attgagctaa taccgaaggt cagctgattg aaaaacgttt
    19741 aatgaagagg ttgtaagcct accgtttaac tctaagtcac aagaaacgat ttcaaaaaac
    19801 agcttttcat gttttatgag tagtgtgact tgtgaccgag gagttggcag gagagcaccg
    19861 gttaccaaat agataggccc gttatggtct atctattttt ttatccagaa aacgctggga
    19921 taaaagaaaa tcacttgttt tgttgaaaaa atgggtatac tgggataaac tgaaatcagc
    19981 aaactatatt taggagtgac gcagttggac gcacgttatg caattatttt ggcggcaggg
    20041 aaaggtaccc gcatgaagtc aaaattatat aaagttttac atcccgtttc tggtaaacct
    20101 atggtagaac atatcattaa tcgggtcagt gaaacgaaac cagatgaagt gattacgatc
    20161 gttggacacg gagcagaaca agttaaagca caactaggag aacgcagtaa atatgcgtta
    20221 caagcagaac aattgggaac aggacatgct gttttgcaag ctgcttcttt cttggaagga
    20281 aaaaaaggaa caacgttagt tatcagtggc gatacaccat tattgactac tgaaacgctg
    20341 aacaatcttt ttgaatatca ccaaggaaaa aatgcaagtg caacgatctt gacggcacaa
    20401 gcagaaaacc caacaggata tggacgaatc atccgtgacc atattgggat cgtagaaaaa
    20461 atcgtggaac aaaaagatgc aacaccagaa gaagctcttg tacaagaaat caatacagga
    20521 acttactgtt ttgacaacga agctttgttc gatgcgttaa gcaaagttgg aacaaacaat
    20581 gctcaaggtg aatactatct aacagatatc atcgaaatct taaaagaaga aggccataca
    20641 gttgctgctt atcaaacgga tgattttgaa gaatcaatgg gagtcaatga tcggatcgcg
    20701 ttagctaaag caaatgagat catgagaaag cgaattaacc agatgcatat ggtcaatggc
    20761 gtaagctttg tcgattcagc aacgacatac atcgatgcag gcgtagaaat cggtccagac
    20821 acattgatcg aagcaggtgt acaaatccaa ggaaatacag tcattggttc tgattgtgtc
    20881 atcgggtcac attcaaaaat cgtagacagt aggattgagg atcacgtcgt cattgaaaac
    20941 tcagtcattg aaagcagcca tgtcaagaaa catgcagatg tgggacctta tgcacattta
    21001 cgaccaaaag ctgaaattgg cgaaaacgtc catatcggaa actttgtgga agtgaaaaat
    21061 gctcaaatcg gcaaaggaac taaagtcggt cacttgactt atgttggtga tgctacgctg
    21121 ggagaagaaa tcaatgtcgg atgtggtgtt gtcttcgtca actatgatgg aaagaacaaa
    21181 catcatacga ctgtcggcga ccacagcttt attggttcta gcacgaatat catcggacct
    21241 gtcgaggtag ctaaaaacag ttcgattgct gccgggtcaa caattacaga caatattcca
    21301 gaatatgcgc tggcaattgc gagagcaaga caagtcaata aagaaggata tgcaaaaaaa
    21361 ctcccttatc taaactaaga cttttgcaaa atcacttgat ttatttaaaa aatatgacta
    21421 ctatttatta ggtagaattc tagagttgtg aaaaagaaag tggaggtccc catgtcaaaa
    21481 cattactttg acccaagatt aaaaattttt gcgttaaatt ccaatcgccc attagcagag
    21541 aaaattgcag cagcagtcgg cgtcgagtta ggaaaatcat ctgttactca atttagtgat
    21601 ggagaaattc aagtaaacat tgaagaaagt attcgtggat cgcatgtcta tgttattcaa
    21661 tcaacgagca gcccagtcaa tgataacttg atggagttgc tgatcatgat tgacgcactg
    21721 aaacgagcaa gtgcaaaaac aatcaacgta gtcatgcctt attatggcta tgcgcgtcaa
    21781 gaccgtaaag cacgtgcacg ggaaccaatc acagcgaaat tagtagcaaa catgattcaa
    21841 aaagctggtg caacaagaat gctgactttg gaccttcatg cagtccaaat ccaaggtttc
    21901 tttgatattc cagtcgatca tttgatgggt gcgccactta ttgccaatta tttcttagaa
    21961 aaaggaatca aaggcgatga tgttgtcgtt gtttcaccag accatggtgg tgtcacacgg
    22021 gcacgtaaat tagcggaatt tttgaaatct ccgattgcga tcatagacaa acgccgtcca
    22081 aaagcaaatg ttgcagaagt aatgaatatc attggacaag tcaaaggcaa aacttgtgta
    22141 ctgatcgatg atatgatcga tacagcaggt acgatcacat tggctgccaa tgctttgaaa
    22201 gaagctggtg caactagtgt gtatgcttca tgtacacatc cagtattatc cggccctgct
    22261 ttacaaagaa tagaagattc agctatcgag cgtctagttg ttacagactc gatctatctt
    22321 ccagaagatc gtaaaatcga caaaatcgat gaagtaagtg ttggcggact aatgggagat
    22381 gcaatcaaac gtatccatga aaacaaacca gttagtccat tgtttgaaac aaaaaataaa
    22441 taataaataa actcacaaag gggagtccaa ttgggctgag attgaatcta tttctaaacc
    22501 cttcgtacct gtatcggtta tgcgagcgta ggaattgtga ataaacagct gtttgactat
    22561 tttcgaaagc tgcttcctcc tttgtgactt ttttattcaa aggaggaagt ttttttatgg
    22621 gaaaaaatag agtttgggta gaaggaacga ttgttgcagc gttagcgatg gtgttgtcgt
    22681 tgattccgat ccagatcggc agcagttttt ctatttcatt agggcagatt ccattgactc
    22741 tttttgcgtt aagaagaggg acaaaggcag ggatgctggc aggtttcatt tggggcatcc
    22801 tacattttcc gttgggacaa gtttattatt taagtgtcgt tcaagtgttg attgagtacc
    22861 cgattgccta tacttttgca ggcgcagcag ggctcatggc ttcaaatgtc caaaaaggct
    22921 atgtagacga taatacgaaa caaattagaa aaagcatcgt gtttggtgca ttgattggcg
    22981 cactttccag atatttttgg cattttattg caggagtggt tttctgggga gcgtatgcac
    23041 tatgggggat gaatccttgg ctcttttctt tcgtaatgaa tggtgccagc gggttgagta
    23101 cagctattgt aacgatcatc gttttattag ggatccaaca aacgactcct tcgatttttg
    23161 tgccagataa acgacaggag ctgtaaataa aaaagaagca agaaacttga gacagaatca
    23221 tgtcctagtt tcttgtttcc tttttatttt ttgataagaa atagatctac ttcaatggca
    23281 gataagaaag atcggcatct tctaccaatt gccagtgtcg atcggtgaca gagtagatta
    23341 aagtagcgat gatttcctct tctcgatacc gggtgccttt taatttccaa atataatctt
    23401 caatcacata gattgggata cgatatttac catcgatcaa accaacttga tcaaaagaaa
    23461 aaatgatccc ttcctgcatc aaattacgca tttctttcaa taattccaca ctgatttttt
    23521 caacaggtgt ttcttttttg aaaaaagatt tttttacatt gatcttatct gacaagatcg
    23581 aacttaattt actagcaaaa atcctataaa attcatctaa atagcgataa taaatccgat
    23641 tcagctgatc attaagatcg aagtatacaa aattattctg tagtttataa aaaaacggcg
    23701 aatgaagatg tgttttcata tgaccaaaat ataataattc tgaaatttct aaaggtgtca
    23761 attctttcag catcgttaaa tcagtaaagt cgatccactt caattcatcg aatccacgcc
    23821 tgttacgaga agaggaaaag aaacgctgaa tattttctgt accacggatt actttcagcc
    23881 ctgtatggga ttcatattct ccagcagaag cagatggatc aagcaagagc aagttttgag
    23941 gaaaatgcac gatactgttt gcaaagtcag tagcagtcag cccttttgtt aaaacagcat
    24001 tacttgtggt atcaatatgt acataaactg actcagtcat catgttcctc ctcttatttc
    24061 ctcttaatct cttttatttt acaacatttg cattaaaaaa gcttgtttct tttattttaa
    24121 aattccatta caaaatcacg ttttcattga aaacactctc attttcaatt aatttttgtg
    24181 atttttgtat ttttttattt aaaggaggtt ttatgaattg ttttcttatg gaatctacaa
    24241 agtcgaatac gagactcatg acctttttat gacgtactgg tatacttgaa gaaaaaggag
    24301 agcgcgatgg agataaaaaa agtttacttt tcacagaaaa tgtcgctgta ttcgcctatc
    24361 cagcaagcaa aacaacccct tccatttttt caaagtcatc aagaaagtag agacgctttt
    24421 tggcgttctg caaaaaagca atgtgctttt aaagcagtat cgaaaaaata taccgtctat
    24481 tttactattg ctaaaagtag aggagatgtt atttttaata atctgttgat tgaaggtgaa
    24541 acttttgaat ggaaaaaatt ttttcggtat atggaagctt gcgctcgttt ttttattaaa
    24601 gaaaactgtt gttttttatt tcaatctcct ctatcagaag aatggttgcg tatttttcat
    24661 aaaaacggct atcaaggaac cacacaatta aataaaaagc tggtctatca tacagcactt
    24721 gttttaggtg gaggaggagc gcacggtgct tatcagattg gtgtgtggca ggcgctgaag
    24781 gaacatgata tcaactttga gattatcaca ggtacctcgg taggtgcgtt gaacggcgca
    24841 ttgattttac aaggagatat gaaaaaagct gtgaatttat ggaaaaagct gtcgacaaga
    24901 caagtgcttg cgttaccaga aatggctgca gttgaagacc ttcgtgaacg cttctatcga
    24961 gaaagacgcc aaatgacgaa aacagcacta attgaaggcg gggtttcttc tgctccattg
    25021 gaaaagatgg tcaaagacaa tttggatttg tccttactca aacataatcc caaaatacgt
    25081 ttatatacgg tgtctactaa actgccagaa ctagcggaag tagtgactga tatccaacag
    25141 acaaaaacag aagaaatacc agattggata ctcgcctctg cttcatttta tcccgctatg
    25201 gcttatcgaa agatcggaaa aaataaatat gcagacggtg ggtatcgcaa caaaatacct
    25261 attgatattg cgattaacaa aggagcaaca gaggcatttg tcgtagatgt gcaagggcca
    25321 ggcccagcga aaaaaattcg tatgccagac atttttatcc attggaaatg tcaaacattg
    25381 tggacactag gcagctttct gctttttgat agccaaagga accaattaaa tttacaatta
    25441 ggctatctgg aaatgaaaaa acgattaggc tattactatg ggaactggta tacatttcat
    25501 tctgttaaac ctgcaagaac atactggcga ggatttttgt cttacttaac aaaagaaatt
    25561 cagttagaat tatctttttt caaaagcata aaattttggc aaaaactgcg taatttatat
    25621 aagaacaggg tcgtaccaga gacatgcgga ttggcgatgc tagaactttt agcaaaaaaa
    25681 cattttttac tgcccaatga aatctatcaa gtagacatga tgattcaaat gatctgccaa
    25741 caagatataa aaagtatgcc ggatgattta ttggcacaaa ttggtcaatt aagtactgaa
    25801 gaatggcgaa ggtatcgaaa ataccagcaa aaaatacaaa atgagcgcac gaaaactgtt
    25861 tattttgatt atctgctaca aggaaaacgc aaggatcgtt tgcagcatga attgcttaag
    25921 caaccagttg acacattact gatcctatat ttatattatc tcaaggagga acaaccatgg
    25981 cacaagaatt ttcatatgaa atcgtagaag aaatcgctat attgtcagaa aacaacaagg
    26041 ggtggcgtaa agaactgaac ctagtcagct ggaatggtcg cccgccaaaa ttcgatcttc
    26101 gagattgggc gccagaccat gaaaaaatgg ggaaaggcct gacattgacg aacgaagagt
    26161 ttgaacaact gcaaaaagca atagaaaata tgtaatgagg aaggaccctg tcgaatgaaa
    26221 agtatgactg gttttggcaa agccatccgc gaaacaaaag cgtatcagtt agatattgaa
    26281 ataaaaagtg tcaaccagcg ttttctagat gttcaaatac gaagtcctaa aatcctgaac
    26341 tttgttgaaa acgattttcg tcagcttatt aaacagcagt taagccgcgg tcgaatcgaa
    26401 gtatttgtga atctagctta tattggcaaa aacgaaaaac agatcgtcat caactgggaa
    26461 ttgattgatt cacttatcac tcaattgaca gacggaattc aacaacgata cggtagtcaa
    26521 aatcaagtgt caattagtcg gatggcggaa cgcttcgtgc tggacgaaaa cttcgtaacg
    26581 gtagaagaaa aaccggaaga gagcatggaa gaattggcac agttagctct agatacattg
    26641 aaaagcgcac ttgattctat tgaggcgagt cgagaaaaag aaggtcaagc tttagcttta
    26701 gtgttgaaaa agaatactga agaattcaaa gaagtactaa aaaaactcga tagttttgta
    26761 gaaatctatg aaaaggaatt tcaaataagg tatcaaaaaa agctggagga atttcttgga
    26821 gcgaaagtcg atgagcaacg gttgttgacg gagctagcca tcttgttgga acgcggagat
    26881 attcacgagg aactggatcg tctggcgatc catgtacaaa aactagatga acttatcgaa
    26941 gcacaatgtc ctgtaggtcg ggaattagat ttcctgatcc aagaaatgaa tcgggaaatc
    27001 aacacgatcg gttccaaatc aaatgcaatc gaaattaaaa atcaagtcgt ccagtctaag
    27061 acgatcttag aaaaaatcag agaacaagta caaaatattg aatgacgaaa gaggtagaga
    27121 taatgaaata ttatgacgta acgttccacg aattaagtgg aaaaactgtg gttaaacggg
    27181 atatcccttc tgaaaaaaac ggctttgacg tatggaaaga tgcctgtgca gactataatg
    27241 agaacgaact gtttattttg atcaacgacg gtgcttacgt gacgatgaat cggaaattta
    27301 ttgttcgaat tgacacagaa gaggtagaag atccgacaga aaaagcacgt tctcgaaaag
    27361 atgagatcat gggtgtagtg aatactttgt ccaatatggg cttttagcaa ggatgctgaa
    27421 caaagaaata caataaataa acagaattgg atttcttcgc ttagcttctt tgctctagga
    27481 atacatttaa aggttgtgac aaaattcgtg tcacaatctt tttttatttt gaataagtga
    27541 tgttcaaaaa ccattttctc ggtattaagc caaatttatg caaaaatgtg agaaactatt
    27601 ttcacaaaat ttttcttcat actcgaaact aatcggcttc ttcacgacct cttatacacg
    27661 gcgttcaaaa gcttgcatct gcgataataa ccccaaccaa acgaaaaaca tgagaagctg
    27721 tttatgtttg gctgttctta ttacttgatg caggacagct tttttacgac ctcttggtac
    27781 agggtagctt ttttaccaat ttctagctat aattaaagat aaccttgaaa gttgcagaaa
    27841 aaaagtgcaa aataaacgat aagtacaaaa agactagttg aaaggacgtc gtcatgtcag
    27901 agcgtggatt attaatcgtg ttgtctggtc catccggtgt aggaaaaggc acagtacgaa
    27961 aagcaatttt tgagagtgag gataatgatt ttcagtattc gatctcaatg actacccgta
    28021 aaatgcgtga aggggaggtc gaaggcgttg attatttctt ccgaagcaaa gaagagtttg
    28081 aatcaatgat cgaagctgga gagatgctgg aatacgcaga atatgtcggg aattattatg
    28141 gaactccttt gtcatatgtc aacaagacat tggatgaagg aaaagatgtt ttcttggaga
    28201 ttgaagtcca aggagcaaaa caagtcaaag aaaaagtgcc cgatggtgta ttcatctttt
    28261 tgactccgcc agatttagcg gaattaaaat cacggatcgt aggccgagga acagatgcag
    28321 atgaagtaat cgaaaaacga atgaaagttg caaaagaaga aatcgaaatg atggctcttt
    28381 acgactatgc tgttgtaaat gatgaagtgc cgctagcagt tgaacgaatc aaaaacatta
    28441 ttgccagtga acattttcga gtagatcgcg taatcggtaa atatattaaa atgttaaagg
    28501 agatgtagtc ttatgatgtt aaaaccttca attgactcac tattagatcg tgtaaattca
    28561 aaatattctc tagtgatttt agcaagtaaa cgcgcgcatg aattggatgc aagtgcacag
    28621 cctactctag attcttttga ttcagtaaaa agcgtcggtc aagctttaga agaaatcgat
    28681 gcaggaaatg tagtcaatga tccacatcct gaattaaaac gtgaacgttt gaagatggaa
    28741 gaagaggaac gtcaagcaca aaaagagcgt gaacaacacg aattggaatc acgtatccgt
    28801 gaagagcaaa aaatgtaata aagaaaaata gagcgaacat ctaaaaagaa aagcaaaccc
    28861 agctgtttcc ttttcaaaca ttcgccactt attgtctggt agaaaaggct gtgtctgaac
    28921 tttttgacac agttcttttt tttcttatct gctgttaatt ttttgttagg atttggcaga
    28981 agataagaca aatccatcga tctctagtaa aataggcaag gaactttttg tcgcttgata
    29041 agaaaagaca aaaaaaggag gaaacgaacc atgacattaa cagctgaagt cattgtggac
    29101 gtacctacta tgcagaccga tcagccattc acttatttgg ttccctctga aatggaaaca
    29161 gctttgcaag tcgggatgcg agtagaagtc ccttttggta atggcaatcg tcatgtccaa
    29221 ggatttgtta tggctatcca aaaatcagaa gaatcagcta atccatcttt gaaggcagtt
    29281 attcgtttgc tagaccttgc tccggtggtc aatgaagaat tactttcatt agctgattat
    29341 atgaaaaaaa ttacttacgc attcaaaatc acttgtctac aaacgatgct tccgagtgtg
    29401 atgaaagcag aatatgataa attgatctat cctttggcag acacaccaga agttcaggta
    29461 ttgtttgatc agcgagaagt gatttcctgg aaggaagcag aagaagaagg cagcctttct
    29521 caattgattc gctggcgcca agagcaatta gtagatatca aatatgaagt ccatacacga
    29581 aataaagtaa aaacgattcg tttggtccgt tctttgttaa ctgaaaagca aatcgaagaa
    29641 gaatgggcaa aattacggca aaatgccaag aaacaaaaag aacttctttt gtgtttatct
    29701 gaactgagcc aagaagaacc aattgcttat ttcaaaaata aaggaatcag tactgctgtc
    29761 ttgaatcaag gaaaagaaaa gggctggctg gagtttatag aatcagaacg ttatcgcgac
    29821 ccttataaag accgagtatt tgaccaaacg acggcattgg aactgaatgc agaacaaaaa
    29881 aatgctgtcg aacaaatcat cacagcaggt cagcagcaaa aagatcaggt ctttttgctg
    29941 gagggaatca ctggcagcgg gaaaacagaa gtatatcttc aggcaatcgc tgatgttttg
    30001 tcagaaaata aaacggctat tatgttagtg cctgaaatcg cattgactcc gcaaatggtc
    30061 gagcgattca aaggacgctt cggagaatca gttgcggtct tacatagcgg actttcccaa
    30121 ggtgaaaaat atgatgaatg gcgcaagatt gagcgggaag aagcgcaagt agtagtaggc
    30181 gcacgatctg ctatttttgc cccgctgaaa aatatcgggc tgatcattat cgatgaagaa
    30241 catgaatcaa gttacaaaca agatgagaca ccgcgttatc atgcgagaga tctagcaatt
    30301 tggcgcagta aatatcatca ttgcccaata gttctaggaa gcgcgacgcc ctctttagaa
    30361 tcaagagcac gagctcaaaa aggcgtttat cagttattgc agttaaacca ccgagccaaa
    30421 gcagctgcac agcttccagc tattgagatc gtagatatgc gtgaagagtt tcagaatcat
    30481 cggacctcta ctttttctgc taatttgcag gaaaaaatac aaaatcgatt agacaaaaaa
    30541 gaacaaactg tcctactgct caatcgtcga ggatattcgt cttttgtgat gtgtagggac
    30601 tgtggatttg ttcttccatg tcctaattgc gatatctctc ttacactgca tatggataca
    30661 cgttcaatgc gctgccatta ttgcggacat gaagaaccta ttcccaatcg ctgtcctaat
    30721 tgtggcggca ataaaatccg ctactatgga acaggtactc aaaaagtaga agaggaactc
    30781 cgagaacttt atccgcaagc taggattttg cgtatggatg tagataccac tcgaagaaaa
    30841 ggggcacacg aacagatttt acaaaaattc ggtgcaaaag aagcagatat attattaggg
    30901 acacaaatga ttgctaaagg tttggacttt ccagaagtga cattagttgg ggtgttgaat
    30961 gctgatacct ccctgaattt accggatttt cgttctagtg agcatacatt ccaattgctt
    31021 acccaagttt caggacgagc agggcgagcg gaaaaagcag gcgaagtcgt gatccaaaca
    31081 ttcaatcctc aacattacgc catagaattg gctaaaaaac aaaattatga gcagttttat
    31141 cagcaggaaa tgcatgtacg gcatcgtgga ggctatcctc cttattactt tactgtgaaa
    31201 ataaccgcca gccatcctga agaacaagta gcggcaaaga aaatctttca gattgccaat
    31261 cagctaaaag aagtgttaag ccctcaaagc ttgctattag ggccaacgcc cagcatgatt
    31321 ttgagagtga aaaaccgata ttattatcaa ctaatcatca aatataaaca tgaaccgaat
    31381 cttcctcatg ttttggatga aattttgaat ggaagccaga aagaacagcg acaaggtctt
    31441 tttgtggcaa ttgacaacga accattaaac tttatttaag aaagggccaa attatgcgct
    31501 atcctatatt gatccaccct aatgataaat taaaaagaac tgctcagcca atcgatgtaa
    31561 tcacggacga gacaatcgct ttattagaca atttatatga gacaatgatt gcgaatgacg
    31621 gaatagggat cgctgctcct caagtaggac aaaacaagag aattgctgtg atcgaagtag
    31681 atgaaggcga gaaatttgaa ctgattaacc cagaaatcat cgaagcaaaa ggtgaaagcc
    31741 ttgacgtaga aggttgtctc agtattccgc atgtctatgg aacggtcaag cgagcagatg
    31801 aagtgaccgt gcgttattat gatcgagacg gagaagagat agaagtgacg gcttttggct
    31861 atttagcccg tgccttccag catgaaatcg atcacttaga cggtatcttg ttcattgaga
    31921 aaatgataca gcagatcccg gaagaagaac ttgaagaata tatggaggaa catcttgatg
    31981 actaagctag tatttatggg cacacctgct ttttctgtgc cgattcttga agggctgata
    32041 gaatcaggtt acgagatcca ggcagtggta acacagcccg accgtccagt tgggcggaaa
    32101 cgagtaatta cgccgacacc ggtaaaaaaa gcggctctga agcacggtat ccgtgtgctg
    32161 cagccagaga aaatctccgg ttcgccagaa atggaagaaa tcattgaatt ggtgcctgat
    32221 gtgatcgtca ctgcggcatt tggccaattc ttgcctgaaa agttattgca agtaccaaaa
    32281 ttaggggcaa tcaatgtcca tgcttcttta cttcctaaat atcggggagg tgcgcctgtt
    32341 cattatgcca tcatgaatgg ggagaaagaa actggtgtaa cgatcatgga aatgatcaaa
    32401 aaaatggatg caggcggaat ctatgcgcaa gaaagcatac caatcactaa acaagatgat
    32461 gtagggacga tgtttgaaaa gcttagcctt ttaggaagaa agctattgct agaaacattg
    32521 cccaatattt tggatggaca aaaaccagta cctcaagacg agtcagaagc aactttttcg
    32581 ccaaacatca cacgggaaca agaagcaatc gattggcata aaactgcaga agaaattgac
    32641 aaccaagtac gcggaatgcg tccttggcca attgcattca cgacctatga gggcatacgc
    32701 tggaaattat tatcggttga agtattggca gaaactacag acaaagcacc tggtacgatc
    32761 atccggaaag acaaaaaaaa tctatggatt gcttgcggta aacagaccgt cttagccatc
    32821 aatgaattac agccagctgg taaaggaaaa caggccgtac atgatttcct taacggaagc
    32881 ggtcagcaag ttcagattgg tcagcaggtg aaataatgaa aaaaatccct aaaaaaatga
    32941 aaaaatcagt acgatatatg gcattactga cattagagcg agtgaacaag ggtggcgcct
    33001 actcgaatct tttgttgaat gagatgatca aacaaagcga gctaaatcaa aaagatgtgg
    33061 gtttatttac agaattgatc tatggtacga ttagccatca gcgactattg gaattttacg
    33121 ttgcaccatt gatcgctaaa gcaaaaaaag tggatgactg ggtcaagatg cttctttatc
    33181 tttctgtata ccaattagaa tttttagata aagtccctgc acatgctatt ttaaacgagg
    33241 cggtcgaaat cgcaaaagta aaaggaaatc ctgggacagg gaaatttgta aatggtgtct
    33301 tgaggaatta tcagcgtcaa ggagcaccag atctgcaagg cattgctgat cctatcgaaa
    33361 gactttctgt caaaatcagc ctgcctctat ggatgacgaa acgactggtg gatcaaatcg
    33421 gatacgaaga aactgaaaag ctcggtttat cgctatatca gcctagccat gctagtgccc
    33481 gagtagatac acgccgactt tccagagatc aggccatcac tgttttgcaa gaagaagaga
    33541 tcacagctga aaaaagccaa gtcagtccat acggtatagt agcgaaaaaa gggcatttag
    33601 cttctagctc attgttccac gatggcgtca tgacgatcca agatgaaagt tcgatgcttg
    33661 tagcgccgtc tatgcaaatc gagcctgaac atcatgtctt agatgcctgt gcagcacccg
    33721 gaggtaagac gacgcatatt gcttcttttt tagatccgtc atgcggtgga gaagtggtcg
    33781 ctttagatgt acacgaacac aaagtcaaac tcattgaaga taatgcagca cgtctaggtg
    33841 tctcttctgc tgtctacgct caaaagatgg atgctagaga agtcagtaaa cagttcgaag
    33901 cagagcagtt tgatcggatt ttagtagacg cgccttgttc aggtcttggg ctgcttcggc
    33961 gaaaaccaga tattcgttat aaaaaacagc cggatgaatt agcgaattta ccaaaaatcc
    34021 aattggaaat tttagaaagc tgcgcaccaa ctttaaagtc ttccggtatt ctgacttata
    34081 gcacttgtac gatcttaaaa gaagaaaacc aagacgttgt ttctgctttc ttggaaagac
    34141 accctgattt tgagaggatt gatgttttga ccaatcctat gctacaatca tcaatcgaag
    34201 agaaaatgtt gactttgtat ccgcatcagt tttacacaga tggatttttc atttgttgtt
    34261 tgcgcaaaaa gtaatgaggt gaaaaaatgc agattgaata tcaatcagat gtaggaagac
    34321 gacgtaacac aaatcaagac tatgccagtg tatttaccag ccgttcaggt ctcaagcttg
    34381 ctgtattagc agacgggatg ggtggtcatc gtgccggaga cattgccagt cagatggcgg
    34441 taacgaatct aggcgaagct tgggaaaaac aagaagctgt tgacgatgaa aaaatcgccc
    34501 aatggttcat tcaatcgatt caagaagaaa atatgctgat ttatcagcgt ggacaagaac
    34561 agccggaata taacggtatg ggaacaacaa tcgtagcggc cgctctgtca gatgactggt
    34621 tcacgattgc caatgttggg gatagcagag cttatttgat tcgtgaagat aaaatcatgc
    34681 aattgacgga ggatcattct ttagtcaatg aactagtcaa atcaggagaa atcagcgaag
    34741 aaatggcagt gaaccatcca aggaaaaata ttttaacacg ttctgtcggc atgcctggaa
    34801 cagtcgaagt agatgtttct actcatcttt ggcaactaaa agatcgactg ctgttatgtt
    34861 cagatggctt gacgaacatg ctgtctgaag aagaaatagg aacgatcatc aatcaagaag
    34921 gcccattgtc tcataaagta actgagctga ttgatcgtgc caatgaagca ggcggagcgg
    34981 ataatatcac cgttcttctt atcgaatata aggaggacag tgtatgatcg agttgggcaa
    35041 aaaattaaat ggccgttatc aaatcactgg aaatatcggt agcggtggta tggcaaatgt
    35101 atttttggcg cacgatttaa tcttggatcg tgatgtagca gttaaagtct tacgatttga
    35161 ctttcaaaat gaccagactg cgattcgacg atttcagaga gaagctttag cagcaacaga
    35221 actcgttcat ccaaacattg ttagtgttta cgatgttggt gaagaagaca acatgcagta
    35281 tctggtgatg gaatacgtca aaggaatgga cttgaaacga tatatccaaa cacattatcc
    35341 tgttccttat gaaacagcag taaatattat gcagcagatc ctttctgcta tttctttagc
    35401 tcataaccat caaatcatcc accgagattt gaaaccccaa aacgtactga tcgataatga
    35461 aggtgttgta aaaatcacgg atttcgggat tgctatcgct ttatctgaaa catcgatcac
    35521 gcagacgaat acgatgctag gatctgttca ttatctgtcc cctgagcagg ccagaggaag
    35581 tatggcaacg aagcagtcag atatttatgc tttagggatc atcctttatg agatgttgac
    35641 gggtagcgta ccgtttgatg gtgaatctgc tgtaacaatt gctttaaaac attttcaaga
    35701 tgatcttcca tctataaaag cacttgatcc aaatgtgcca caagcactgg aaaacgtgat
    35761 tttacgggca acggctaaag aacctgcaga ccgttataag tcagccgagg aaatgtctga
    35821 tgatctttct acagtattat caccagctcg tgcaaacgaa gaaaaatggc agcctcatgt
    35881 gatggataat gaaacaaaag ttatcacacc ccttacggaa gatgcaccaa tgcctgattc
    35941 attcaaatct atgcctctgc caaaagacaa gccagaaaac gaaaccttac cagaggagga
    36001 agaagttctg cctgatccta aaaagaaagg acagaaaaaa tggtggctga tcctattagc
    36061 tattcttgct gttttaggaa tcggaacagc tgtattcttt gcttctggcg ggcgaggaga
    36121 agttgttgtt cctgatgttt ctgatctttc tgaagcttct gctagagaaa cactcgcaaa
    36181 agcgaaatta gaagtagcaa caaaaacaga agaaattgca gatgacaaaa tcgaagaagg
    36241 taatgtagtg aagacagacc cggcagcggg aacgacagtc aagcaaaaac gcgaagtcac
    36301 tctgtatatt agtagcggca cgaaaaaaat caaattagat gattacagtg gtaaaagtta
    36361 tgaagatgcc gaagcaagtt tgaaagaatt agggttttct gctgacttga ttcaaaaaga
    36421 agaggaattc agttcagagg tagaaagcgg aatgatcatt tcgcaatctc catcagaaga
    36481 tacagaagtc gatcctaaaa cagacacgat tactttcaca gtcagcaaag gaccagaaac
    36541 agtgactttg agtagtcatg taggagaaaa ctacgaaact gttcgtaatt ggcttgttac
    36601 acaaggattc aatatcaata atattagtgc tacttatgac tatagcgaca ctgtaccatc
    36661 aggttcgatc atcagtcagg atccagcctc gggtgaagtt gtagcagaag aaacttacat
    36721 caattttgtc gtaagccaag gaacagagcc taaattgaat gatatctccg gctatacaaa
    36781 aagcgaagca caaagttatt tagctagtgt cggtgcagaa tatatcgggc atgagacttc
    36841 cgaatattca aacacggtgg ataaagataa agtgattcgt acagtaccag gggcaggaac
    36901 gacaattacc aaaggaatgg ttgtgaacgt aatttactct aaaggaccag atccagcgtc
    36961 ttctagttct gaaaaagact cttcagacag ttctagcagc tcaagtagct ccagtagcac
    37021 aagcaactct tcaaaagaag aatcttccag ctccacaagt tcatcagcta gcacctcaga
    37081 aagttcaaaa taagtgctga ataaaatata tcagaaggga atgcgacatt gatttgttgc
    37141 attctctttt ttgtgtttct atctcttttg atcaattttc aagccatata ctttgagaag
    37201 tttgcatgga ataacaccta ctttcctctt cgtatggtaa aataaacaaa aacggaggtg
    37261 gcacttatca aaggacaaat cagaaaagca atcagcggtt tttactatgt atacgcaaac
    37321 ggagagacct atcaaacaag aggaagagga aatttccgga atcggaaaat cacgccgctt
    37381 gtcggagatc aggtgatctt tgagagtgaa aatcaaacag acggctatct tctggaaatc
    37441 ttgccgagaa aaaatcaatt agttcgccca ccagtcacaa atgttgatct tggaatcatt
    37501 gtcacaagta tcgtagagcc tgcattttct tataatctac ttgaccgctt tctagttacc
    37561 ttggaatacg agtcgatcga accgattatt tttttgacaa agaccgactt gtcagacgac
    37621 ccagaaaaaa tcgaagagat caagcaaacc tatactaaaa taggctatcc ggtgattgta
    37681 cccaatcata cgggtgatac gacagaactg atccgttact tcccagaacg gctatcggtc
    37741 tttatgggtc agtctggagc aggaaaatcg acgctactga atcaaatatc accggaactg
    37801 aatttagcaa caggagagat ttctgatgca cttggaagag gacggcatac aacacgtcat
    37861 gtggaactga ttcctatcta tggcgggtta gtagcagata caccaggatt tagctcgatt
    37921 gactttttga caattgaagc aggagaactg ccgagacaat ttcctgaatt tgtagaagct
    37981 tctgtccatt gcaaatttag agagtgcatg catgctaaag aacctggctg cgaagtaaaa
    38041 catagagtag aaacaggtgg tatcgcacag acacgttacg acaattattt gcaattctta
    38101 caagaaatcg aaaaaagaaa accaatgtat gcaaaaaaag aaggtaaacg aaaataggag
    38161 gaaacaagaa tgaagatagc accatccatt ttgagtgcag attttgccaa tttacaaaga
    38221 gacattgagt tagtggaaaa aggaggcgca gattacatcc acgtagatgt aatggatggc
    38281 cgatttgtcc caaatatcac attagggcca aatattgttc aggcaatccg tcctgttact
    38341 aaattaccgt tagacgtcca tctgatgatc gttgatccag aaaactacat tccagcattt
    38401 gcaaaagctg gagcagatat cattactgtc cacgtcgaag caactcctca tattcatcgg
    38461 gcacttcaaa tgacaaaaag cttaggagtt aaagctggag tagttatcaa tccaggaaca
    38521 ccagtctcca tgatcaaaca tgttttgcct ttggctgatc aagtactagt catgactgtc
    38581 aatcctgggt tcggcggaca aagctttatt gaagaaacag tagaaaaaat tacggaactc
    38641 gctgatctac gtagagagaa caattggact tatgcaatcg aagtagatgg cggaatcgtt
    38701 ccagaaacag caaaaatctg taaagatgca ggggcggatg tcttcgttgc aggatcatat
    38761 atctatggag ccgaaaatcc agtcggacaa atcgaacgat taaaagaggc attagactaa
    38821 atgaaaattt tattagctgc tggaggtaat ccgcaaaact ggccgcagtc tctgctgtcc
    38881 aaatacgatg cctatgtcgg gatagaccgt ggtgcgctgt acctgcttca agcaggctac
    38941 ccagtagatc tggcagtggg tgattttgat tcattgtcga acgaagagca gaaggaagta
    39001 tttgcaaaag ccaaagagta tacccgttcc cctgcagaaa aagacgatac agatacacag
    39061 ttaggtatct taaaaacatt tgaacgttac ccgcaagcgg aagtcacttt gattggagct
    39121 acgggcggaa gattggatca tcttttagcc aatctctggt taggtatgga acctcgcttc
    39181 aaaccctttg cccatcagct tattatcaga gattgtcaaa attatttgtc ttattatttg
    39241 cctggagagc atatagtaag acagatacca gatatgaagt atttagctta ttgctgcttg
    39301 actcccgtct cgaatcttac attaaaaggc agcaagtatg tattggaaaa taaagaagta
    39361 gaatatccga catcttatgc aagtaacgaa tttctttcag ataccgcaga attttctttt
    39421 tcagatggta tgattgcagt tattcaaagc aaagattgat ccataaacaa ataaaaaaat
    39481 ttgtctttca ggctaaaaat gacagaatct attatttgct aaaaaaaagc ttaagaggag
    39541 caacttacct tttgtttcac ggcatttagt gataaaattg aacacaagag tctaattaat
    39601 tcgaggtgtc tttgtgaaga agttcaatcc taataaaaat attattatta ccttggttat
    39661 tgttatcatc gtggtgacga tactaagtgt gaccgctgcg cagcgagcga atgaaggaaa
    39721 gcccaatttc ttccaatcca tcgttaatga cagtgttgca atggttgata aaacaatctc
    39781 tgccccagta cggtgggtac gaaatggagt agattctgtc cataatcttt tttcaactta
    39841 tgccgaaaat gagcggctaa aagaaaaaat cgatagctat gatgacgttt cacagcaaaa
    39901 caagaattac gagagagaaa tcgaagcgtt gaaaaaagaa cttgagttga atcagacgct
    39961 gactagttac gaaaaagtaa cggcaaatgt cattactcgt tcgcctgaca gttggcagga
    40021 catgctgatc gtagacaagg gttctaaaga cggtatcgaa gcaaatatgg cagtcatgtc
    40081 gcaaaaagga ttgattggcc gagtgatcga ggtcaatacg gcttcgtcta aaatcgaatt
    40141 actgtcatcc tctaatgaaa gctccaatca ttttccagta cgggtatctt cggctaatgg
    40201 cgaagcgttt ggtttgctta aaaactatga tgaaaagctc catgccttag tggtgaccca
    40261 attaactggt gatacggata tcaaagaagg ggatgttgtc cagacatccg gtcttggagg
    40321 gaattctcca gctaacttgc cgatcggtac ggttattaaa acgaaaccag atagttatgg
    40381 gctggatcgg gaagtttatg tgaaacctta tgcagaaatg tatgacgtgt cagttgtgac
    40441 gattgtccaa cggctagcgg aggattagtc catgttgaag aaagaaacaa tgaagtacta
    40501 tctgccaatc gttttgttct ttttgatgtt gatagatggt catttaacaa gaatgctagg
    40561 ggagtggtcg aaaggcacct atatgtcaaa tgcccacttt ctgatattgg cattattatg
    40621 ttgcagtatg gcgtttgaaa aacgttattt actgattacc acgattgttc tcggggctat
    40681 ctatgacgct tactatattg gcgttatcgg tatctatgca gtagctctcc ctttaattgt
    40741 atggttgatg tatgtaatga aagacgttat ccatgtcaac atctttactg aatttttcag
    40801 tatgatcatc tttgtcacgg gttatgaatt gtttacgatg gtggtccagt tgatttttaa
    40861 attagcagta gtaaataaca cgtattttat tacaaggttt ttaggaccta cactgctgtt
    40921 gaacatgatt atatttgtat tattcatttt tccctttaag aaattattca gtgatgaata
    40981 atttcttttt ttatttttag gtcgaaagcg aaaaagaatc gttgttatct taagaaatgc
    41041 tagacttaac gcggcttttt catgatcatt ttctgaaacg aacagttttg tcatttttaa
    41101 aagttgtttt gaaacatttt tgtaacataa ctattatatc gttgacacac tgctatggta
    41161 caatttttat atcgttaaga aagacttaaa tatatttaga tatttattaa attaagccag
    41221 tcggaggaat gaagagtgaa aaagagttta atatcagcag taatggtatg ttcaatgacc
    41281 ttgactgccg tagcatcacc gatcgctgcc gcggcggacg attttgattc tcagatacaa
    41341 cagcaagatc aaaagattgc agacttgaaa aatcaacaag cagatgcaca atcacaaatc
    41401 gatgccttag aaagccaagt ttctgaaatc aacacacaag cacaagacct attagcaaaa
    41461 caagatacat tgcgtcaaga atctgcacaa ttagtaaaag acattgcaga tttacaagaa
    41521 cgtattgaaa aacgtgaaga tacaatccaa aaacaagcac gcgaagcaca agtaagcaac
    41581 acaagctcaa actacatcga tgctgtattg aatgctgatt cattagcaga tgctattgga
    41641 cgcgttcaag caatgacaac gatggtaaaa gcaaacaacg acttgatgga acaacaaaaa
    41701 caagataaaa aagctgtaga agacaaaaaa gctgaaaacg atgctaaact aaaagaatta
    41761 gctgaaaacc aagctgcttt ggaatctcaa aaaggcgatc ttttatctaa acaagctgat
    41821 ttgaacgtac tgaaaacttc attagctgct gaacaagcaa ctgctgaaga caagaaagct
    41881 gacttgaacc gtcaaaaagc agaagctgaa gcagagcaag ctcgtattcg tgaacaacaa
    41941 cgtctagcag aacaagctcg tcaacaagct gcacaagaaa aagctgaaaa agaagcacgc
    42001 gaacaagcag aggctgaagc acaagctact caagcttcat ctactgcaca aagctcagca
    42061 acagaagaat catcagctac acaatcttca atgactgaag aatcatcatc agctacacaa
    42121 tcttcagcaa cagaagaatc aacaacacct gaatcttcaa cagaagaatc aacagcgcct
    42181 gaatcttcag caacagaaga atcaacaaca gcgcctgaat cttcagcaac agaagaatca
    42241 acaacagtgc ctgaatcttc agcaacagaa gaatcaacaa cagtgcctga atcttcaaca
    42301 acagaagaat caacaacacc tgcgcctaca acaccatcaa cagatcaaag tgttgataca
    42361 ggaaacggca caggaagtag tactccggct ccaacgccaa caccaacacc tgaacaacca
    42421 aaacctgtaa cacctgctcc agctccttct ggaagtgtga atggtgcagc aatcgtagca
    42481 gaagcttaca aatatattgg tactccatat gtttggggcg gtaaagatcc aagtggcttt
    42541 gactgctcag ggttcacacg ctatgtttac atgcaagtaa ctggtcgtga catcggtggt
    42601 tggacagttc ctcaagaatc agctggaaca aaaatttcag tttctcaagc aaaagctgga
    42661 gacttgttat tctgggggtc acaaggcgga acttaccacg tagcgattgc tttaggcgga
    42721 ggacaatata tccatgctcc tcaaccaggc gaaagcgtaa aagttggttc agttcaatgg
    42781 tttgcccctg actttgctgt cagcatgtaa gaatga
//
LOCUS       DACCVH010000015        38014 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.015, whole genome shotgun sequence.
ACCESSION   DACCVH010000015 DACCVH010000000
VERSION     DACCVH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.015"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(424..1368)
                     /locus_tag="IVV98_000881"
     CDS             complement(424..1368)
                     /locus_tag="IVV98_000881"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP7806555.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1664..2608)
                     /locus_tag="IVV98_000882"
     CDS             complement(1664..2608)
                     /locus_tag="IVV98_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806556.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2829..4043
                     /locus_tag="IVV98_000883"
     CDS             2829..4043
                     /locus_tag="IVV98_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7806557.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4065..6080
                     /locus_tag="IVV98_000884"
     CDS             4065..6080
                     /locus_tag="IVV98_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HAP7806558.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6163..7536)
                     /locus_tag="IVV98_000885"
     CDS             complement(6163..7536)
                     /locus_tag="IVV98_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP7806559.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7562..7846)
                     /locus_tag="IVV98_000886"
     CDS             complement(7562..7846)
                     /locus_tag="IVV98_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7806560.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7848..9863)
                     /locus_tag="IVV98_000887"
     CDS             complement(7848..9863)
                     /locus_tag="IVV98_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7806561.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10042..10347)
                     /locus_tag="IVV98_000888"
     CDS             complement(10042..10347)
                     /locus_tag="IVV98_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP7806562.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10436..11467)
                     /locus_tag="IVV98_000889"
     CDS             complement(10436..11467)
                     /locus_tag="IVV98_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP7806563.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11674..12549
                     /locus_tag="IVV98_000890"
     CDS             11674..12549
                     /locus_tag="IVV98_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7806564.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12701..13543)
                     /locus_tag="IVV98_000891"
     CDS             complement(12701..13543)
                     /locus_tag="IVV98_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7806565.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13635..15512)
                     /locus_tag="IVV98_000892"
     CDS             complement(13635..15512)
                     /locus_tag="IVV98_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7806566.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15509..16930)
                     /locus_tag="IVV98_000893"
     CDS             complement(15509..16930)
                     /locus_tag="IVV98_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7806567.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16933..20322)
                     /locus_tag="IVV98_000894"
     CDS             complement(16933..20322)
                     /locus_tag="IVV98_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP7806568.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20579..21970
                     /locus_tag="IVV98_000895"
     CDS             20579..21970
                     /locus_tag="IVV98_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7806569.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22043..22690)
                     /locus_tag="IVV98_000896"
     CDS             complement(22043..22690)
                     /locus_tag="IVV98_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7806570.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22698..23384)
                     /locus_tag="IVV98_000897"
     CDS             complement(22698..23384)
                     /locus_tag="IVV98_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806571.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23390..24463)
                     /locus_tag="IVV98_000898"
     CDS             complement(23390..24463)
                     /locus_tag="IVV98_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP7806572.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24685..25359
                     /locus_tag="IVV98_000899"
     CDS             24685..25359
                     /locus_tag="IVV98_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806573.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25364..26704
                     /locus_tag="IVV98_000900"
     CDS             25364..26704
                     /locus_tag="IVV98_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7806574.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26853..27839)
                     /locus_tag="IVV98_000901"
     CDS             complement(26853..27839)
                     /locus_tag="IVV98_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP7806575.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28563..29594
                     /locus_tag="IVV98_000902"
     CDS             28563..29594
                     /locus_tag="IVV98_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7806576.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29703..31235
                     /locus_tag="IVV98_000903"
     CDS             29703..31235
                     /locus_tag="IVV98_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP7806577.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            31374..32186
                     /locus_tag="IVV98_000904"
     CDS             31374..32186
                     /locus_tag="IVV98_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP7806578.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            32176..32661
                     /locus_tag="IVV98_000905"
     CDS             32176..32661
                     /locus_tag="IVV98_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7806579.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32684..33229
                     /locus_tag="IVV98_000906"
     CDS             32684..33229
                     /locus_tag="IVV98_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP7806580.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33302..34945)
                     /locus_tag="IVV98_000907"
     CDS             complement(33302..34945)
                     /locus_tag="IVV98_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP7806581.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(35074..37302)
                     /locus_tag="IVV98_000908"
     CDS             complement(35074..37302)
                     /locus_tag="IVV98_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP7806582.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(37335..37814)
                     /locus_tag="IVV98_000909"
     CDS             complement(37335..37814)
                     /locus_tag="IVV98_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806583.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        11092 a         7196 c         6909 g        12817 t
ORIGIN      
        1 aaaaatgata aacctctctc gaacggtttt ttatcaaaaa tcgtcatttt tccatcaaaa
       61 tctgcttatg caaaattata aaaaaatttt gcagtttttc ttactttttt tgtcgtttaa
      121 ttgaatgata aaaaccagtt tctttattca gttaatcaaa tatgaacgaa ttagatatga
      181 atcattgtat ttgccgttgc ggaaggattt tttaattaac cacagataaa cattgataac
      241 gattcgctta ttgtaatcaa cagattaaat ttcatatgtt catatgtacg gatacatttt
      301 cggaccgatt aattttaacc attctgttta tttgcttacc tattagatat caataaaaaa
      361 ctgcttaaca gctatttcag ctgttaagca gttttaggat ttttagttca tattcattgt
      421 ttcttataat acagtgttca atacttctct taaagcactt gttgatttgc tgaacattgc
      481 tttttcttct tcgttgattg ataattcaac aacttcacga acaccatttt cgtcaacgat
      541 tgatggcaca cctgtaaaga tatctttttc gtcgtattca ccagttaaat aagcagatac
      601 aggcaataca gcttgttcgt tattcaagat agcttttacg atacgtgcag tactcatacc
      661 aataccatag taagttgctt ttttacgatc aatgatctca taagcagcat tacggacttt
      721 atcagcaatc acatctaatt catcttgggc aatacgatgg tctttttcta caatttcaaa
      781 cactggttta ccaccgacag ttgtatgtga ccatgcagca acttctgaat caccatgttc
      841 acctaagata tagccgtgga cgctgcgtgg gtcaactttt aatttcaatg cgatttcttt
      901 acggaaacga gttgtatcca atgttgttcc agtaccgata acacgtgatg ttggcagacc
      961 agattcgttc caagcgatat atgtcaaaat atctactggg tttgaagcaa caacgataat
     1021 accgtcgaat cctgatccca tgatttcttt tacgatttgg cgcatgattg acgcatttgt
     1081 tttaactaaa tctaaacgag attgaccagg tttttggttg ataccagctg tgataacaac
     1141 gatatcagca tctttacatt cttcatagcc acctgaccat acagccacat tttcatcgcc
     1201 ccaagccata ccatctaaaa ggtccaatgc ttccccttct gctttttctt gattcacatc
     1261 gatcaatact aattcattag agattccttg gttgatcatt gcataagcga tacttgttcc
     1321 aacaaaacct gtaccgacga ttactacttt acgacttgtt tttttcatga ataaacagct
     1381 ccttttcata actatttgtt actttcatga aaagtatagt cttgtttatt cattttatca
     1441 acatgttaat tataatagtt gttattataa tttttgatgg aaacgaattc ctgaatacgc
     1501 ataacagata aatgacaaat gtttacacct atatcccctg ataatacaac caaaagttta
     1561 gaactgaaaa taaatccaaa aaaattcgct gcaacgatat aataagacag caatcgcacc
     1621 taaaacaatt ttccttcata tgctttagtg aaagattttc ttcttaatgt ttatttctcc
     1681 attcattggg agtacatgtt gaatacttct tgaataattt gaataaagaa gtcgtttgtt
     1741 tatatccgat acgattagcg atttcttcca acgaaaaact cgtttcttga atcagttcca
     1801 acgcaaagtc gaattttttc tttagaacca gttcttgaaa ggaagcatca aaatacattt
     1861 tcaatttatt actaagatag accggattgt agccaaaatg agctgctgtt tcttttaacg
     1921 tacaagaagt aaaatgctta tcgatataat ctaatactct aagcatctca ttttctgcgc
     1981 atccatctgc tgatgaaaag ctttgttgtt ctaataaatg agtcaattcg atcagtaata
     2041 gtgatgtata gagatttaac gaacggatct tatgactgta tgtatcaaaa taaatcaaca
     2101 gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc gccgcgaaaa tgaatgaatt
     2161 gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa agaagaaagt agattatttg
     2221 tgcttgccaa atgattcaat atctctgtag ataaggtttc ttcttttaat aagatgttga
     2281 ttaaaatatc ctcttgccct gtgtattcga ttctttgagt agcttcttta tcaatgatca
     2341 ccacgtcact ttcttccatc tctatccttt ctccattaat aatttgtaaa catgtaccgc
     2401 tatacatata attgatttca acaaaatcat gtgtatgctc gggaacttcc gcatatcgac
     2461 ggtgtttact gatatgaata tttccctgtt gaaatagatc ccctcggtgg atttttggcg
     2521 gtgtctgaag atggtaagct aagtttaaat cattgatatt cattccttgt tcacgctgca
     2581 gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta attcagctag ttccaattga
     2641 ctccctcctt tttgtaagcg gtttctttcg cttattagtt cacgctgtac tgctattata
     2701 tgcaaagcta tttttggttt cataaagact ttctatggtt gggacatgaa cttcctgtga
     2761 ttccgctatt gagagaataa ccacttcata ctatattttt gataagcgct tacaaaaatg
     2821 aaaggaacat gcttatgaat aaaaagatga tgaaattttc tctgctgtca gtctctctta
     2881 ttttgacttc tgctggtgca gtcacgtctg caattcccag tatgtcagct acttatgcca
     2941 cgcgttcttt atctgctgtt gaattattaa cgactgctcc ctcttttatg gtcactattt
     3001 ttgttttgat tagtagtttt attgctagga aaatcggaca aaaacaaact gtgatcatcg
     3061 gattagtgat tgcatcgatt tatggtatcc tccccctctt ctcacaaagt tacagtattg
     3121 tcttagcttc aagagctgga ctaggtattg gctttggatt gatcaattct ttggcagtca
     3181 gcatgattgc tgccttttat cacggagatg aacgagcctc tatgattggt tttcaaagtg
     3241 catttcaagg atttggtgca gctttaatga catttgttgc aggacagcta gtacagttcg
     3301 gttggcaata taccttttta gtctacgcca tcagcttacc tattcttgtc ttgtttgttt
     3361 tgtttgttcc tacacctgaa acaactgaac ttcaatcaca tggcacagcc ccaacaagac
     3421 aagtaatcaa aacgaatcct aaaatgatta gttatggtat ttttctcttg ctggtcatcg
     3481 tggtatataa tgctgtatcg attaaattag ccacagtcct gacgacttat tctctaggaa
     3541 acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt ggcaagtatg gctgccggag
     3601 tttgttttgg ctggcttcag acaaaagcac atcgctatat gcttacactt tctttactac
     3661 tgatgggaat cggctttgta ttgattgcca ctgtgataaa cctgtatgtg attgggtttg
     3721 gtgcgatcct aacaggaatt tctttttcgt tattcattcc ttacttattc aaccaagtaa
     3781 gtatccaagc gcccaagtac gcggagagtt tcaatacttc aatcttattg gttggcgcta
     3841 atttaggtac tttcattgca ccatatggtt tgctctttct ctcttttgct tctcttggga
     3901 gtaaaacact tgctgttttc gtcaatggca gtatcttgct gttgattagc gcgcttatta
     3961 gccttctagt agtacacagg acgaatagaa agacagtgat aagagtagat gaagaaataa
     4021 aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg taaaatgaca aatgaaaaac
     4081 ataaagatag atggctttgg tatcctggag actttgagat ccgccatgga ctgctacaaa
     4141 atttccaacg ggaagaacga ggttttgact ggccagcgta ctggtacatg gatgattgcc
     4201 atcggaacgt caagtttaag agatattact ttcttgatca accttccatg tttaaagtga
     4261 cgatccaagg agttgggtat gtagaaatta atggacaaaa acatccatgt ggaaaatggc
     4321 tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt aggacataca tcagggctac
     4381 cagcgatgtt tatcgaggga gacgaagtaa aatcagatat tggctggaca gcaagtaatt
     4441 ttattgaaga atatccagct ggctggagtc cgctttatgt cgatatcgca aaagatccaa
     4501 atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac tgaaacggag attggcggag
     4561 gaatcttatt cgattttggg cgagcagtga atggctgtgt agaactaata tctctggatg
     4621 accatatcga atctatcact ctatgttatg gagagtccga tgtagaagct atggatatcg
     4681 attattgcta ctataagcaa ataggaatga caagaaaaat gaaagctcgt aaacgcgctt
     4741 ttcgctattt gtttatacca gaggtttcta ctggaatggt tcaacttcaa gtttttcatg
     4801 aatttttatc tctttcgaaa caagctgctt tttcaagcga ttcttcttta ctgaatcaga
     4861 tctggtcagt atcagaagaa accttcaagt tatgtagtga tttgtttttt atcgacggta
     4921 tcaaacgaga tcgctggatt tggtctggag atgcgtatca atcattcatg atcaatcaat
     4981 atcttttttt tgacgaggaa atcaataaac gaacgatatt agcattaaga ggacaaaatg
     5041 aaatcaagca gcatatgaat actatcgttg actattcgat cttgtggttg attggtatcg
     5101 aaaaccacta tatgatgacg aaagactatg aatttttacg catcgtctac cctaagatgc
     5161 aatcattaat gagatacttg atggagcaaa cgaatgaatt agggtttatt tatgggagag
     5221 caaaagattg gatatttatt gattggtctg aaatggataa agaaggaacg cttgctgcag
     5281 aacaagtctt attactgaaa gcctatcatt ccatgatcac ttgcggagat atcttagctg
     5341 aaacatatgg agagaacgaa aattatcata ctcatctcta tcaagaaaaa tatcaactat
     5401 tgaaacaaaa cctatttgac tacttttggg atgaagaact tggcgctttt atcgattgct
     5461 atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat tttcgctgtt ttattcgatt
     5521 ttgctaacaa agaccaacag caatcgatct taaagaatgt cttattgaat gacactatca
     5581 cacagattac tactccatat ttcaaattct atgaacaaga tgctttatgc aaactcggac
     5641 agacgaatat cgtctaccaa acgattcttg attattgggg agggatgtta tctcatgatg
     5701 cggtaacttt ctgggaagaa tacgacccta ctcaaacagg aaatgaaaag tacagtatgt
     5761 atggagatcc ttatggaaaa agcttatgcc atgcatgggg agcaagccca atctatcttt
     5821 taggacgcta ttttatcggt ttgtatccaa caaagccagg ttatgaagaa tttatgatac
     5881 aacctaatct agattcattt gaaacactga attgtacgct acctatcaaa gatggaaaga
     5941 tttcgcttga aaaaacaaaa gataagatcg tgattacttc tgatagaaca ggcggaacag
     6001 tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca gccacttgtc ttaacaagct
     6061 attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac atatcagaag actttaaatc
     6121 ttcttctgat attgtccaag caatttttat tttgaagttt gcttaattct gttctttaga
     6181 aacaatgttt gttctttttc cggcaaaaag aaagctagat aatacgacaa gtaaaaagaa
     6241 agcgatgatt ccaactgtca aggctatttg accgtattct cctagtttcc caagtacaag
     6301 tcctggtact agataatcag tatcggcaaa tgtagaagaa gcgattttaa gatctcctaa
     6361 tactggaagg ataaataatg gcagccaact aatcaataag ctattgaaag cagaacctaa
     6421 taccgcccct cttctaccgc cagtcgagtt gccgaagaca ccagaagcag ctccgcagaa
     6481 gaaatgtcct actaccccag gaatgataac tgtagtttgc aagcctatca tagcaaacat
     6541 ggatagtgtt cctacaaaga agctaacaaa aaagccaatt aatacagcat taggtgcata
     6601 tggaaaaacg ataggaacat ctaatgctgg tttagaatcg ggtacgagtt ttttagcaat
     6661 cccttggaat gctggaacga tttctgccaa caccattcga accccttgaa ggacgataac
     6721 aaacccagct gtgaatgttc cagcttggat cagtgcaaag attacagcgt tgtctccatt
     6781 gcttagttct ctttcaacaa atccaggacc agctaacaaa gcaagtgcga catatacgat
     6841 cgacatcaag agcatgatcg atacagtaga atctcgcaaa aagctgaaac ttttaggaat
     6901 ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac tttccgatcc atccactaga
     6961 agcataaccg atatttccgg tatgccctaa cgcaacttga ttgtttccag tgatgttctt
     7021 cataaacggt tgacaaagag caggcgtaat agttaatagt gttccttcga agaccccgcc
     7081 taataagatc atccacaaat ttgcagtaaa ccccgcgctt actaaaatga ctgctgttag
     7141 acaagaaaca taaagcattg cttgacctgt aagaaaaatg aatttatatc ttgtgaatct
     7201 agcaagtaaa atattcacga tcatccctac tagcatgatc aaagcagtag gtgtaccgta
     7261 ttgttgcaaa gcaatcgcca ctactgcttc attgctagga actactcctt gagtatgcag
     7321 agctgtttgg aacatcgaag caaaaggggt tagtgaatta ctgattaaac cagcaccgcc
     7381 gatcagtact aggaatccga caaatgtttt gatagttcct tggatcactt ctgaaaattt
     7441 cttcttctga agaacgagac caagcagtgc aatcaaagaa acgaggatgg agggctgact
     7501 gacgattgac acaaacaaat tcaacaattt atccattgat agttcctccc ttgaatcatt
     7561 tttattcttt tgacaagatc ttcgttactt tttcttttac ttcttcgctg tcaatgatcg
     7621 attgcaaagg tacgagcttt tcatcaggta tagaagttag cgtatctttc aaagaatgct
     7681 caatgaagaa ataatcagcc atatcgctag atacacttcc aacatccgta tgacttactt
     7741 caaactcgtc cacatctgct ccaagatctg caagtgcttg tttgatgttc atctctacca
     7801 taaaacttgt tcctaatcca ctttgacata ctgcaaaaat tttcatatca ttcgtctcct
     7861 tttcttatga tcgctaatat ttcttctttt gttgatgcgt gtaataaatc ttgaagattt
     7921 tgtttattag aaagtagctt tgttaaattt gccaaagccc gaagatgtgc ctcattatcg
     7981 atagcagcta aacagatgaa caaactaatg ggatgggctg gattatcaag cagatccaca
     8041 ggttgttgaa gtttcagcaa agacatccct acttcgttta cgccatcttc tggacgagca
     8101 tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac catactgctc cacgcgctcg
     8161 atcatagctt tgatataact ttcttctatt ttattttctg ataatagcgg ctgtgcggca
     8221 aatgtgattg cttcttgcca gttttttggt tgatccgata attggatcat ttcttctgtt
     8281 aataattcag atagcatagg acgttgatcc tccttctttt ctaaaagttt gttcatttta
     8341 cgatttaata cttgatagag cttttcttcg tctacgcctt cttttaattc gatataaggc
     8401 agtagcgccg acaacaattc ttgggcagaa ggcattgaaa atcctggtat cagccaatct
     8461 ctttgtactt gattgatcag ctgatttttt tccaagtcag tcatgattgg atgcagaaca
     8521 tagagagact ttttcttatc agtaagtgtg agaggtacag tagaaaaaat aatatcgtaa
     8581 gaagtttcgt caacctcgtg taagcggtca gctgaattag tctctgtaaa aaagatcatc
     8641 gggaataatt gctgaagttc actttttaag atcaatgaag agctaatgcc acttggacag
     8701 acgatcacgg ctcttatttt tctatttctt tcttctgcgt ccgcttttct gatctctccg
     8761 ccaaatagta tagtgaaaaa accaatctct tcttcaggga tgctcttccc tattcgtctt
     8821 tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg aagcatattg atgcttaatt
     8881 tgatcgatca tcacattagg taaataaaaa gaataggaaa tacgaaaata ggcagggacc
     8941 aagtgataaa agacattcat caataattca cgaaacgaag caaattctac ggccatcagg
     9001 aattccatgc gatggatgac ttctgaagaa cattccagca aaaaatcaag tgcaggctcc
     9061 tggacatctc cttcaacgat cgatgctaag caaagagaga aaaatataat ctccgaattt
     9121 tgatgttcgg aatagccaag gccagtcaat acttgtcgac taatgtcagt gactgcaaga
     9181 gaagccaaca gttcagcatc ttttaccagt tccatggatg tttttccaat tcgaatggtt
     9241 gtcaaactca aataataagc taattcatcc attcgatttg gtgcgaatcg aagatctgat
     9301 agtgaaatcg ttttatctag caaatctcta actttggcgt aataatcaat ggaaagggtt
     9361 gcggttaaat acgtgagccc aaatcttcca gcaagtgact gcatcaaacg agcagtgcga
     9421 ttttttgctt ctcttcttaa tattgcttct gaccctagca gcctaaaacc agttttccta
     9481 gtatacgaca gctgacaatc ttccacttct aattcatttc ttatcttttt gatatctgac
     9541 aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat gaaaaacaga aacagacgtt
     9601 gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct cttgttcggt atacacagct
     9661 tcaaatcgag taatatccaa aaatttttct gcccagtcga ttgctcggaa tttctttata
     9721 cggatacggg tatcatccac atattcggca aaaggagtta attgtttgat cgcctcgctt
     9781 gtatttactt cgatgatctc tgctgctttt tctagactga tttctcttgg tgttttcagg
     9841 agataactaa ttttgtagtt cacagcgctg ttcacctcct acttatattc tagtatggta
     9901 gcgcttttaa atcgaggggt gtttggtaca acttacagtt ggattttttt tacgactgta
     9961 ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg tgaccaaatg tctcctgctt
    10021 ttatgaattg atttcgtccg atcaatgatg atcatgttta ttttttgagg tcagttcttc
    10081 aaatttttct ttgacatctt caaccgcttt ttcgatatct ttttcaaagt gattgggctc
    10141 attaggcttt gtttcctctt ctacagaatt tgaaccagat aaagctgttt ctttattttc
    10201 tgtttcacca gagtttgtgc cagctaatga ttcttctttg tcttctgttt caccagaatt
    10261 agttcctgct aaagccactt cttcttctgt tttaggggcc attgaacctc ttaatcgttt
    10321 gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct agtagttcta tactttttca
    10381 tcgtacaata agacagttta tgcgtcaaaa aacaaacccg attcttacaa atatgtcata
    10441 tttttccttc tgattcttga atgcttttga ttccttcttc caaaattttc atttgtaaga
    10501 ttgtttcttc atctttgatg actttttctg cgccattaac taatgtctcg taaatccctt
    10561 cgtagacacg gctgtaatca ccaacctcgg aaattacttt ttcttcatga taactccctt
    10621 gttcatctat ataggtcaat acaccataat gttcgggcaa atcgatacca aagtcttcat
    10681 gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg atcttttgtt tgtttcacga
    10741 acatcccttt ttttccgtaa acgacgaaac ttggacgttc tttgatgcgg aaataactgg
    10801 attttatcga aattttcata tttccataga aaaaatccag atcgaagtaa tcattcattc
    10861 gtcctttccc taaaagttga cgtacatcat agctgatatc atctggttcg ccgaaataag
    10921 aaagaacttg atctactgta tgacaagcat gtccatataa atagctgttc gcagtagaaa
    10981 attcatgcgt attttctggt acttccggtc tgaaataatc ataatgcatt tctacttcta
    11041 aaatatcccc taattttccg ctttcgatta ctttttggac tgtcaagaag tcagaatcga
    11101 accgtctgtt ttggtaacat tggataaata gacctttttc ttttgctaat gcaaataact
    11161 cttctgcttc ctttgacgtt tctgcaaaag gtttctctac tagtacattc ttaccatgtt
    11221 cgagtgccat ttttccatat tcataatgaa attgactagg tgtagtgatg acaactaatt
    11281 ggatctcagg atcatcccaa agatcagaca gctgatcagt atattcgatg tcttcgaatg
    11341 ttttccacac tggttcagat ggggaaaaaa tttttttgat attgattttg ttcgtaagtt
    11401 ttcttgaaaa aggcaaatga tagcgatttg tactctttcc attgccaaga taagcgattg
    11461 taagcatgag tggtgcctcc ttttattgat gttttcagta tatcctagaa aagcgcagaa
    11521 agtatttata atagctattc tggtaaaaaa gttcagaaaa acacttgtta tcattcggtt
    11581 tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa gatagtagcg gaaccaagtg
    11641 tttatcagta agatagaatt tggaggtcag atcatgctta ttgaagaaaa actaacaaaa
    11701 caagagttgt ttaccacgac agagaaacgg attgtcgatt acatccgtag gaatatcgaa
    11761 gctgcagtct acatgacgat tgaagaatta gcaaaagcta cgtatacttc ccattcagct
    11821 atcattcgtt tatgcaaaaa aatgggattc agcggattta aagaattccg tttcgagctg
    11881 gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa cgattgatcc taattttcct
    11941 ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa tggcggattt atcgatccag
    12001 tcaataaaaa aagcacaatt gcagattgaa catgaagatt tagatcaaat cggtaaagta
    12061 ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg attctcaaat cacggcaagg
    12121 aaattccaga ataaaatggt caagttgaat aagtttttga tcatggctga agaatacagt
    12181 gattcttctt ggaatgcagc caatttgact agcgaggatt gcgccatttt tattagctac
    12241 agcggtcgca tccatcatta tgaacgaata atgacctatt tgaagcatgt agaggcccct
    12301 accttgctga ttaccggaaa tcagcattca gaaatggcca aacaggctga tatgtgtctt
    12361 gttatatcgc aggaggaata tgattttgct aaagtagcga ctttctcctc tcaaattgcc
    12421 ttcgattacg tattaaatac gttattctca gtgatatatt ctcaaaattt tgaagagaat
    12481 atccgcaact tgaaaaacaa acaagaattg atgcaaaaag gccttcttaa agaatatcgg
    12541 aaaacttaag aaaagatcct catttagtaa taagaaagat agtgtttgat aggctctctt
    12601 tgatatcatc ataaaaacag gctgaagttt tctttttcaa acctcagcct gtttgtttac
    12661 ggaacgattc gaatagatat attatagaaa tgaggaatag ctaacttctg tttcttattt
    12721 tgaacgattg acgaaaaaga tatataagaa ggaggaaaat cagtatacat gcagctaaca
    12781 atccatacag gaaaaatcgt ttgttctcgg atactttctg tacttctttt tgaacttctt
    12841 ttgcatgata aggaacccgg tgccctctga caagtaagcg atgactgttg accatataag
    12901 gtgtacaagt taggagtgtc acgaaatcct gccctttttc gattctcaga tcttttgtat
    12961 cagtcggttc taccgtcttg atctgatcga cttgataagc gagtgtccgt ccattgattt
    13021 cgatatagaa agaatcacct aaagtcagtt tcggtaagtc tgtgaacaac tttgcttgag
    13081 gcagtcctcg atggctggaa ataacggcat gtgtattttc tccccccgta ggataagacg
    13141 ttccttccaa taatgaggca cctttttcta gcagcacagt attcgtttca tcaaaaattg
    13201 gcaaatggac attgatctca gggatcgtca aaataccgat cgtatgtttc tcaaaatagg
    13261 ttctatcctt tttcgcaggt tcttttttct tagtaaaggg atctgcacct ggatttccac
    13321 cttcttttgc taattgctgg tttttctttg tcatgttttc ttggatttta gccatgactt
    13381 cttcattttc tttgaccgct tgttgctgat aatgagagat gatctgctga tccagataat
    13441 tattcagcgc gtcgctaaca aatggataag ctagtatccc tattcctgag agaagcaaga
    13501 aaagcatcag cagatctaga agtttccttt tctttggttt catttgtgtt ctccttgtga
    13561 tgactgtttg ataataaaag aaaaaggagc atttgcgtaa tccgctgctc ctttttccaa
    13621 ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag caaagtacag tccagcaatc
    13681 agtagaagga ctactcctgc accgatatac acatagattc ccttaccgcc tgttgaagga
    13741 agtgtacctt tgtgtttatt tggtattttt tcaggagaaa tcaactgtcc tgctgttaca
    13801 taagattgtt catcgatagt aaatgctaca cggtttgtta atggaacata tttttctggc
    13861 gctttcgttt cttccagata gtacgtgcca tattttagac ctgtcacatc gattaaaccg
    13921 ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg atacccagct gacggctttt
    13981 gtggatgggt cgatcgataa atatttcgct gtgtcactat cttgatcacg aacgacgaat
    14041 tctgctccag caagtgtttg gtctgatgta acgtcaccat ctactttaac aaatcgtttg
    14101 cccccagtaa cgacatcgac tgacggtggt gtttgatcat ttgtatgccc gttatcgaca
    14161 tttgcttggt tagaaaatcc tttggttgga tctgcttttt cgttcaaatg catatagtaa
    14221 acgaatttca atgtaccgcc aggagttaat gaaggaatat aattcggatc aactgaaacc
    14281 gtgaatccgt ctgtttgctc agtgacagaa taatttactg ggtcgatttc tttatttcca
    14341 tcatataagg cataagcata cgttcctgaa gaatcattat caaatgttaa agcagcgtca
    14401 tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg ttccttcttt atcagcgata
    14461 cctaatggga tattgacaga aatctcatat tgaatttttt caccgattgc gacatctttt
    14521 ccattcaatt gaggtgttgt tttatcaact ttagacgtat catttttgat ggtcttttct
    14581 actggtgttt ggctatttgc caggatctca aaaggcgtga ttgtttgctt ttcaatcatt
    14641 tccgcattat caggagcttt tacttcttct aaattatatt ttccaacttc taaatgatta
    14701 acgatcaact ggcctttttc aatagatgcc tcggcaaagt cattgttgcc gatgtcataa
    14761 gaatgaccag taatgaaatg tttggctttg gtttgatcag ttgtccaagt gtacaatcca
    14821 tctgtgacac tttggatgta ttttttgacg cttggtgttc cttcttcttt agaaataata
    14881 aattctgctc catttagtgc ttcgttttcg gcagtaccga tttttgtaac tttcaacgtt
    14941 ccatcattac agactgtatt tttagggtag agatggatag tatctagttc ttctgtcccg
    15001 tatttataag agccatctgc ttgtttgatc atctcatata cagggaaagc taaaaccatg
    15061 tttgcggcag ctgacactcc gtcttttggt tcttctttga tcgtgtagac tgcatctttc
    15121 ccattttgtt ttttaggtaa agataaagtg acatttccat cagcatctgt cgttcctgaa
    15181 gcaactggtg taccaggagt caaagactgg actgcttgtt ttgctgcatc cacggacgct
    15241 cctttatctc gttgcgcata aaattcttga gtgacgttat aaactgaaaa tgaaatatcg
    15301 gctaatcctt ggtattgatc gaattcgctc atttctttcc cgctgttttg gattaaagga
    15361 tcgggtaaat cagtcatttt ctttttatga aggatgactt gagctgctgt ctcctctgca
    15421 aacacttttt ttgcgccgaa gctgtttgtg agtaatggta aaataaggaa aaggactcct
    15481 aacataacgt ttattttttt atgatttttc attttttcac tcctgttctt tttttgataa
    15541 acaaccagat tgcaaagctt gcgaatacca taccaacaac gcctaaaagt gtatttttcg
    15601 tttcgtttgt ttttggaaga aatggacggc tattttcttt tttattgact actttcaata
    15661 tactgtccgc ctctttatcc tcagaaagaa aagttgaaat ggtaaacgga atttctgttt
    15721 cacttaaaat ataaccagaa ggtgcttcga tctcttttaa tcgataactt cctgttttca
    15781 acccggaaat tgaaaaagcg ccatttttat cggaaatcag gtgaagcgca tctgattcgt
    15841 tctttgtcca cttgtatccg ttggctgttt gctggaggta atttcctgct ttgtttttaa
    15901 taaggaatac tgcgccagct aatcgtttat ctggtttatt tgtctcgatt ttgacaaatt
    15961 gcttactccc tgtatataca gagactttct ttgtactgac accaaaacca aaatccagtg
    16021 ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact gcttagctgc atctgataag
    16081 aaatggtcag tttttttcca gcatattttt ccaacgaagg gatcgaaaat aaaacatcaa
    16141 atccgtgagg tttcttgtgt atgacaaagc cttctgtcag cttttctcca ttcgatgaaa
    16201 tcgttaaact attaggtaaa aacgttaatg cttcatccgc actatctgac aattcgaact
    16261 tttgatagtc aaggatattt acaggaattg tcgtatgcaa ggaataagtg attttttcac
    16321 caatcgtaaa atcatttcta ggctcttcta ataccttctc aaaaggtgga tcagggtagt
    16381 cgttttcttc atttttagga tacaaatgga tagttgaaag tttttgattg ttttgtccat
    16441 gtacaggaag aacaactacc atattctctg ccttttcttt gacgacttct ggtactttgg
    16501 attcaatgaa aagatacgct ttatctcttt tttcttgatc tttagcggcc agagaaaaag
    16561 aagcgatacc atcttcgttg ttaagagttg tagttgttgc ttctgcggta aacataccgg
    16621 aagacgcacc gttttttgcg atctctgctt gtgcttcttc taccgttttg cccttttccc
    16681 gtagatggta aaaagaatct gtgacatcat aaacttggaa tgtgacacca tttaatcctc
    16741 gatacgtttg taataaagct ttttcttgtc cgtcatttgg atgatttttc ggcagttgcc
    16801 cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat ttctgtttct gtttctgttg
    16861 ctacctgagt aaaagctggt ttaaatagta acaagaagag acacatacta agccaaccaa
    16921 gttttttcat atttagctgc cccctctttc ttttttcaaa aaaagatacc aaatagaaaa
    16981 cgcacaacca atcatcccta ctagatagat tcctaaacgg ccaattcctc ccgtttcagg
    17041 taatggtact tttgcctgat tcgtgatgtc taaagaaatc tggttgtttt tggctcctgg
    17101 tgacagaaca gattcatgat cttgtccatc cacttgaatt gacccatctt cgtgtataac
    17161 tatagtaact ggctctttta gaccttggta tccttctggt gtaaaagttt cggtcagcgt
    17221 ataagttcca ggttttaaat tttcgaatag aaaggtatct gtttcttgtc catcttttgg
    17281 cgattctaag tccatttctg gtccctgcag tctgaatttt gctcctttta atgtctgtcc
    17341 gttgtcttct tttttgtgta ccgttagatc aaacgctttt agtcgatttt gatgagtgag
    17401 cgtccataca ttatttgtca tctcggtatt ttttcccgtg taaatgattt ttccatattt
    17461 atcgatttgg aattcataat ttcccggcga agtatcatat ccggcaggac cagctgtttc
    17521 aacgactcga tatttaccag gtgtgagtga atcaaaactg gcaagacctt tttcattcgt
    17581 tgtttggctg tcaattggct gataagtacc atttgcttct tttttctgta gggaaaatgc
    17641 tgctccttta agatttatct ctttgtccgt cccttgcatc gcatacttac gtactgctac
    17701 aggaacttca acaaaaggat tttcaatagt caactggatc gtatcatcgg aagtagtgac
    17761 tgtttttcca tcaatggtta ccgtaccatc agaagcgatc ttgatttccc aagtagtctt
    17821 tttgcttaat ccatgccctt ctggagcttt tgtttctgtc agcgtatagg tcatttcttt
    17881 ttgcaatttg acattttctg gaagagaata ggttccgtcg ccatgatctg ttagtaaagt
    17941 atcaatagaa tctcctgtta atttgaaaac agcgccaata agatcctttt cacctgtaga
    18001 ggaatttttc gttattttca agtttaacgg tgtgaattgt ttagtatttt tccatgtcat
    18061 tgcatctatt tgttgagaat cgtatcctgg tacaggtaat tctttgattg tttggtaact
    18121 gaatgcttga ccttgattat tgtattgagg tagtgataat atctcttgat aactttctcc
    18181 gctatttgca gataatttgt caatgtctgc acgttcccac gtatttgttg tatctttagc
    18241 tggtttaatg attcgaatat atccgttttt ccaagctgca gcatttgtcg tatgttcccg
    18301 ttgaatctca aaagtaactt gatctggacg atcagctaga ttgttgtcaa attcttccca
    18361 taactttttg atgtgaagac tgactccggg agctttagca gatggtatac cgaattcagc
    18421 taattcattg gtatcaatgt ttggctggaa agttgtcctg ccgttcattt gataccagaa
    18481 atttggatgg aagtcctcat tttctgtttg gattctcact tggtaatgga tttggatttc
    18541 ttggtctttt cctaaataga tctgattgct cttgatggta tttccttcta tggaaataga
    18601 tggagtgacc gttgtaggac ttgtccccac actcttgact gaaagtgtac caggctgata
    18661 aatgaatggt tctgcgattg gatcatttat ttgtccattg cttacagttg ctgagatctg
    18721 tacagctttt ttggctaggt attcagagat atctgttgca tgatcagctg attcatagta
    18781 aagatcgcct ttttcatctg atgaaaccat ttgtcgcata cgagactcta cttctgcttt
    18841 tgagagacca gctgccggat cgctttgaag ttggatgcca agaccatgta tttcgattcc
    18901 tcgttctttg agtgccatcg cttctccgat ggttgcgata aacgtactgt cgattcttct
    18961 ggatagattg ttttggtcag gtgcatcata gattcttgag attagagaag tatttcccgg
    19021 ccgatcttgc gtattagaaa actgagttcc gtaataattg ctgcttgatt gtgcgtgtac
    19081 ccgctgtact ttataggaaa atgttggtac accatccgtc agcaaaacga tcactttttt
    19141 atgtccattt ggaacggata gcatgcttcc tgcatctctt agtgcttttt gtgtaaaagt
    19201 accaccattt gtccgtgaag gtgtaatgga ttttacttga tttttcactg aatcaaatga
    19261 acccatctgt actgcaccgt tactgtagct atatccttcg cttgagtagc cgacatatcc
    19321 catattgatt ttgtctgtga taccgctatc tgctaaagta tcgacaaaac gatcgacacc
    19381 aatctttact tcaccgatcc gattattgtc gttcatactt cctgaccagt ctacgaccaa
    19441 tacgagatca agaggcgtga tatctttttg tacatttcca cgagcattca aataaacatc
    19501 aaacaatccg ggtgtacttg tttcctttgc atactttcgt atcgcatagt ctgcttgatt
    19561 accggttcct ccatattcga tatacgaatg ggtccgatca ttaggatctc cattccaaga
    19621 atttatacca tcccattgat ttgttccgtt tttattgcct tgatgatcaa gaacatttgt
    19681 atttcctgta ggttgccaac tggctttagg ataagtgccc tgatcatctg ttgtatattc
    19741 tgtaggaatc gtttgattag atggcacact cacagctggc aaggataatg taggcaatgt
    19801 aaatgggctg acagaatttt cgttttcttt tgatgattct tcttctattt cgtctggctt
    19861 tggtactgac acatctgtat ctttcttatt ttctgtctca tcaataatgt catattcttt
    19921 attatcgacg atcagcttgt ttgcctggct gtggtaaagt gctggatcga ttggaaaact
    19981 cagatcgata gtttgtttag tgtttgatga gatttccaac gtaattttcc cgctatttac
    20041 ctgataagca tagccatctc cttcttttct ttccacatca cttaagtaat tttcgactag
    20101 accaatttct ttttctatct tttcagcact ggtgttattc gcatttagct tgatgttcag
    20161 tgcttttttt ccagactgat ccgaaatgac ttcagctgaa attgtttcta aaactgttgg
    20221 atcatctgta gtgtctgcta ttgcagataa tggcacaaag tttgataaac tcaatattat
    20281 cagcatgaaa ataactttca gtttcttccc tgtggtcgtc atttttcccc tcctttttct
    20341 ttttttctgt tttgacgtga atagtgaaaa ttattaaaat aaacaggcgt tacataattt
    20401 tatttatttt aatatgataa ttattatacg aagggcgcta aagggaatca caccaatttt
    20461 cataccaatt ggtttcattt atgaagttga ttccttcgat taatgagcgt ttcattgaaa
    20521 gaaaagggtt gagggagaaa aacatatgat caggttgttg gaatgcaact atagaaagat
    20581 ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg atgactaaaa aagaacttgc
    20641 caaacgaatt ggtagttcag aatctacatt tgtaaggtat atcgaagaga tcaaaatccg
    20701 ctggggaacg gatgtaacga ttcaatcttc acaaaaattg gggtatcgtc ttgaacattt
    20761 gaatgtacca gcttatttaa atgttctgat ggaaatgtcg caaagttcta caaacagtcg
    20821 tttattaaat gagattattg tcaatccggg taaaacgatt gagtattatt gtgaaaaaat
    20881 ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa tgcaatcaaa ttttagaaag
    20941 ctatttatta aaagtgatcg ttgaccaagg ttttcagtta actagcctta aaagtgagct
    21001 ccagttgcgt atctttgtta cctttttctt tttaagttac tacggaagac gcacgttgcc
    21061 atttccaatc gaaaaaaaga agatcaaaga aattatggtc aagaataatt gtcagatgaa
    21121 tttgtttcag gaagaaagcc catatgagca atctttcttt attatgtatt ttgttgtgca
    21181 tctcatgaga gaatcccaag gaactccatt tgaatggaaa gctggagact cttatgtaca
    21241 gttgataaat atcgataaaa aagacttctt aatcttgaaa aatctcttag gaaaattgaa
    21301 gtacagcagc tatataaaag tagtgaacta ttttgtcaat acgatttttt cagaattttc
    21361 ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa aatatgtcct actgttcgtt
    21421 ttcatccgct gattgcaaag aaaaaaacga agaatatgtt gttcaattat taacgcaaat
    21481 ttattttttc tcccgtattt tcccatacga tacgactcat ttgacgatcc gtgcaactta
    21541 ctttgcacag cagatgcaac accgccagat acgtctatat gctggatttc gtgcagaact
    21601 tcaattttat tccactctac tgaatcagaa tctgatttat tatttatcta gctatatctt
    21661 ttggatgctt atcggtaatc ctgaaattca ccattatact tctgataaaa aaatactgat
    21721 tatcagcgac ttaagtcttc gacatagtca atatattgaa gaatatatca gtgatattct
    21781 tgctgtgcat aaaattcact ctgagacaac tgctattact gaagatcagc tgtcgaaata
    21841 caatcttctc gagtatgatc tgatcgttac gaatcaaccc attttgaatg cccatgttcc
    21901 tcatatattg attgatgata gtgtgtcatt cgcaaatgaa gaagaactca tccgcttatt
    21961 cgagttatga ataatcaaaa aacagctatg tataaaccac cctgataaaa atttcaggac
    22021 aaatacacat agctgtttct ttttattgta ttccttcagc aatccaacga gatttatagc
    22081 gaaagtcttt taacaactct tcttttgtcc aattatttgc aatgagatcc gtcaaagtgt
    22141 tcattacgag ggtcatggaa aagtatagga aactaactgc ttcttccgac gattgaatgg
    22201 agaaatgatt gattcttaat aattccagcc atttttcgtt cattggagaa tcagccgata
    22261 gttctctacg tttggttgtc tgctgatcat ttcgctgggt taacaagtat aacctttgcc
    22321 aatagatact ttcgtgatct aagtcgcagc accactctaa atatttttcg atccccaaaa
    22381 agaaatgttg tttgttttcg ctaatgaatt ttaagatatc ttgatggact atgtgagaac
    22441 tgcttttgat cgtatacaaa taagcatctt ccaaatcttg aaaatattta taaaaagcac
    22501 cgcgcgacat ccccatcttg tcaacgattt ctgagacttt gacttggctg atgtgctgtg
    22561 agcaaaatat ctccagtaat aggtcatcga ttctctgttt ctttgcgttc gataaattga
    22621 aaaaagtttc ttttggcatc cacatctctc ctttatctct gattatacgt ggatagccct
    22681 tcattgtcat gaaggattca ttccttcttt ttctcttctt ctgtcaagta cccatcttcc
    22741 attcgataaa cgcgatcact ccattgaatc atacggacat catgagtaac cataatagtc
    22801 gctttttgtt tctcatgagc ttctttaact agtaatttga cgacttcata tgcatgatct
    22861 gtatccaaac tagctgttgg ttcgtctgct aagatcaagc ttggctcatt atataaagcg
    22921 cgagcaattg ccactctctg tctttctcca ccagaaaggt ctttaggata actattttta
    22981 agtgactgga tatctaaaga ttgcagcaag gaatcgattt ttgttgaatc ttcttttttt
    23041 gaagtaactt ggtcaactag ttcaaattgt tcctttaccg ttaaaaaagg aatcaaatta
    23101 gagctttgga gaataaatcc tatttcttta aagcgtaaat ctgctcgttt tttttctgga
    23161 agctcagtta gtgagtgacc gttgatcact atttctccgg aagtcggtgt ttgcaatcct
    23221 cctgaaatgg taaggaaagt acttttacct gaaccagaag gaccaatgat gctgacgaat
    23281 tctccttcct ttacataaaa atcaattgct ttcaaagctg agacctttgt atgaccagaa
    23341 ccaaatgttt tggtaacttt tttcatcgtt aatatttttt tcatttttat taacctccta
    23401 ttgctgtaat tgggtctact ttggttatcg tacgtatcga aaacaatccg cctagcattg
    23461 cgacaatgat caaaatccca ctatatagca accattgtga ccaaaaaaca gcaaaaggca
    23521 tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa aagagcaagc agaacgccta
    23581 ccaccccaac aataaaggac tgtgctacta aagatttagc gatgaagaaa tttttgatcc
    23641 cttgtgcttt cattactcca aaaatagcag tcttctgaag tgtcatcacg tacatgaaaa
    23701 taccgaccac ggcagcaacc actaagaaca aaaagtatat catcgcattt aaggtcatat
    23761 tttgggcaga atagccagga atactttcaa tgaatgtccc aatagttaat aactgtagac
    23821 ccttcgatgc tttttctttc gaaattttag ctgaatcctt tattacgatc ccattgatcg
    23881 gctgttcttc ttcagaagca aacggctgtt gtccatactt caaagcagtc cacgtatcta
    23941 gggacgcata gatgacggga gaaactgtgt aataagtttc aggaaagata ccgacaatcg
    24001 tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc aattttatag cctgaatcag
    24061 ccagattttg agagatgatg atttcattct ttgttttaaa ttcatgccct ttcgtgagtt
    24121 ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt aacattttct ttgttttttc
    24181 ctttgattgc tccgctgtac aatccgattg gtgctttctc tcctccttca atgtatttca
    24241 gatctcctct tgttaattgt gaagctgcaa atacttgatt tgcatcctcc gacaaaacaa
    24301 tctcttgtgc gtcccaatca tcgattgctt ttttaaactc ttctgaaagt ccattcgcta
    24361 gtcctgacaa catgaatacg acatacgcaa tcaagaacat aataccgacg atcaagccat
    24421 atcgtaattt agaatagcga atttctttga tagctagaaa catttgtttt tcctccctat
    24481 gatagattga tagtgacaaa atgtcacttg ttgaatagtg taactctaaa gtgacaattt
    24541 gtcacttgtg ttgttttttt cttatcaata aattgtctaa gacatctttc gataaaacct
    24601 taacatgagt cataaaaaat ttatttaagc cttatttatg ctttccatga taaactaaag
    24661 tgaccaaatc aatgaggtgg gaaaatgatt aaactattag tagtagaaga cgataaagta
    24721 ttatccaata atataaaaga aatactcgct gcaatcggcg agataacaca agtttatgat
    24781 ggtagtgaag gactgttcga gttggaaagt ggagtttatg atcttgcaat cttggatttg
    24841 atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa tacggaaaga aaaaatacag
    24901 actccagtat tgattttgac tgcaaaagat agtttggaag ataagattga aggatttgaa
    24961 cgaggtgcag atgattatct aacaaaacct ttctatcgag aagaactgat catgcgcgtg
    25021 aaagcattat tgaaacgctc gctaggtctc tttgatgaaa atgttctgaa gtataaggat
    25081 atcagttgtg atttaaaaag caatgaagtc ttgtataaag aacaagtttt gcccatacaa
    25141 ggaaaagagt ttgaattgct cgtttatttt ttacaaaata agggaatcat tttgacaaaa
    25201 gagcagatat ttgaccggat ctggggattt gattctgata cgacgattac agttattgaa
    25261 gtttatatga gcaacttacg aaaacatctg cgaagtactg gattggataa agaaatcaaa
    25321 accttacgta atgtcggtta tatactgcaa agggtgtgat gcaatgaatg gagatattac
    25381 acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca gcatttgctt ttatcttttt
    25441 tcttttggga ttcattactt tacagatatt aaaccaatct gcatacagag aaacagatct
    25501 gtcattagag aaaataaatt ttgattctcg aacagtacaa ttagagatac aaagatatca
    25561 gcaaggcgat ccctttttaa acccgactca aacggaacaa aacagaacaa acatggaaca
    25621 gccattaatg gaaccatcaa atgaccgttt taacactcaa gtgatcttgt ggtctaaaaa
    25681 tggtgagata ttgaataaag cagctattgg tgggcgtttc aaccaaatca aagaattaaa
    25741 aatggatacg aaaaatctga ataccatcca aaatattgaa ttaaatgaag acagtggctc
    25801 atctgccctc tctttccgtt cgattacgaa aaaagcggag acgaatcaag atggcgttgc
    25861 ctacatccaa attttagaaa atacaaatca aatcaagaat tcattagcga cttttcgcac
    25921 gattatgatt ttgtgtatga ttgttttttg gattctctct attggtatca gttattactt
    25981 gtctagtcta agcatgcgcc ctattattct ttcttggaga agacaaaaag aatttgttga
    26041 gaatgcttct catgaattgc gcacaccgtt aacgattatt caaaatagtt tggaacatct
    26101 ttttaccaag cctaatcata ctattattga agaatccgaa agcatcgctc aagcattgtc
    26161 agagacgagg cgcctcactg gattgacttc ggatttgctg acaatcgctc ggaatgattc
    26221 tgatcagcag ctgctttcaa agcaaatgat caatacacaa gaatatatcg aacaacttgt
    26281 taaaccattt caagagatgg ccatcataga tggaaaagag tttattctcc ataacgatgc
    26341 aacattagaa gtaccaattg atgaaaaaaa aatccatcaa gttttggtta ttttgctgga
    26401 taatgcatta aaatatacga atccagaaga taagatcatt ttggattcat ctgttaacca
    26461 taaagaatgg ctgattcacg taaagaatac tggcccttct atcagtgaag aagatcaagc
    26521 aaggattttt gatcgatttt atcgggaaga tcaatctcgg gcgaaagaga ctggcggata
    26581 cgggcttggc ttggcaattg caaaacaggt aatcgaacag catcatggac agatttctgt
    26641 atccaattat cttccacaag gagtcgattt taaagtccaa ttgccgttga agcctaaaaa
    26701 ataatgctta tccctaaaaa agggctgtga caaaaatctt gtcacagccc ttttttgttg
    26761 cgaataaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt ctttaagctg
    26821 accacttctg tcacaacctc tttagcttac gcttacgatt ttttattgcg gtcttcaatg
    26881 tgtacatcac cgcttgtgtc aatatccaat tcttctcggc taacatcttc tgtcactttt
    26941 tcaacatctt catgttcttc tttatgaatc ccaacttctt cacgaataac tgtatgtttg
    27001 cttacatcta cttgctcttc tttgattggg atagtaatcg tgtcatcttc caatttttcg
    27061 tctgttccct gtgaagattg atctgttact ggtttgcgtt cgatgacgat ttcttcacgt
    27121 ttgaccggta cttctaccgt ttcagtatcg ttgaccacat gtttgtggat gtcgacttct
    27181 ccagttgtca catcatgtgt atttacatct aatttttctt cttttagttg aattgtatca
    27241 tcatctagat ttggtttgcg atcgatgtct tcagtcttgc ttgtacccat tgtatcagtc
    27301 tcgccaggta cgtccatcgg atcagttcct ggtgtcatat tcaatggatc cgttgtattt
    27361 tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc cagtgccagt ttctaatcca
    27421 gtccccattg tgcttgctgg gctaacagta tcttgtgtat ccattgtatc ttctgttgtt
    27481 tctggctgac gatagccttt tactgtgatg acaaattttc catcagaaat atctcctcta
    27541 tattgatata aaggatcatt ttctggtgta gccgtctcag aatcataggt atcaaaagaa
    27601 aaagtatctt ttattttttc ccataaagaa cggtcttctt caccatccat ccgattttca
    27661 tctgtttcaa catctatacc agacaatccg tcaaatccta gtctagatgc tgcttcatca
    27721 gtagtataaa taacgatatc atctcgttca tacccttcgt tacgcaaccg ttcaattact
    27781 gataatgctt cttccctcgt actatagctt ccgatgaccg ttaaattttt ctcttccatg
    27841 taaattcctc ctagcaaata gatttatgat tggtatattg ttacttataa atttattcta
    27901 taggagacga ttgttttcta caaatattta gattggaatt tgattaaaac aatttaattg
    27961 aaatttgaaa acatttatgt taatgaaagt catattctaa taaaatgtca tttgtttcta
    28021 tatgaatttt tatgaaaaat ttcatataat ttccactcgt tgtgatggtt taatttatcc
    28081 aatccatcaa taagcaaaca acttatataa aaaaggatta attctcaata taattgctcc
    28141 taccatagaa taaatcttca tgtaaagtaa tgaagtacca actatttcta atacttcttt
    28201 aagaattatc ccaacaatat cgttagacaa accattattg aataaatgga gagccaatcg
    28261 attctgaaaa aatgttttct aatttttcgg aaataaaaga aagagcctcc tgccattaga
    28321 acgaaccaaa tccatttcat tgctcatgaa gtaaccacat agctaaaaag aggataaatc
    28381 aattaaaaga tcaaaagaat gactgcacta ataaaataac taaaaatgta tcttcttact
    28441 tcatatcttt tagctagtac ttagttaaaa atttgcttcc taagatcaag acaaactgtc
    28501 tatcttcatt tgatgaaatg cggtaaaata tagaaaatga acactattgg agggaatttg
    28561 taatggacag caaaactaga aaacaactgc aagaaaagtt aaagcaacgt acacacttgc
    28621 tcccttccgt ctttcaacag tttttagaag aaaatcgttc ttccctttca ttaggcagtc
    28681 gctatgaata cgcaaaagat tttcatctgt ttactgatta tttgagaaaa gtattttctg
    28741 aagaagtgga tgatcagctg attatccatt tagaaaaaca agattatcag aatttcttag
    28801 ctaaaatcta tcgacatact cgttcgttcc aaactacagc gaaccaagaa acggagcaat
    28861 tgtttgaaaa tagctattac gggatttcaa ggaagcaata ttcattaaat cattttttac
    28921 gatttttgta tcaaaaagga ctgattgaag aagagatttc tcttttgggt acaagtttac
    28981 cggaaacaac caaagcagct ccgcgatata tcgatgcaga acttttcaaa gattttgagc
    29041 atttgtttat cccgattgaa ggctttcaaa caagcagaga agctagcttt gaagaaaaga
    29101 atagaccgag gaaccttgca attactgcca ttcttctgta ttgcggatta aagatccatg
    29161 aagtagtaga acttaaacgt aaagatgtat ctttgaccaa gcagattctt aatctgaata
    29221 gaaaagaaaa cagactgaat aaagtaccaa taccaaaaga agcgatgcca tttctggaga
    29281 actattttaa gttaacagca caaaatacgg acgaaaattc ttttgttttt cgttcctcac
    29341 atgatcagca aatttctcct cggactattc gccaaatttt gagcaaaatt acagtatata
    29401 aaaacgtatc gccagaacta tgcagaaaaa catatcgtta ttatgcagaa ctatatttag
    29461 atgatgctga cgcggtaaat tatttatgtg gtaatcgata cctctcatcc cattcttttc
    29521 aagatatctg ggaaaagatg gttgattttt cttatcacga attagcggca ttcgttcggg
    29581 tttcttccat ataaaacaaa tgtatgatct ttttttcaca ataaactatg ttattatata
    29641 aaggattatg ttacgattat cttgaatttg tatattactt aacaaaagat aatggagtgt
    29701 gaatgatgga gaccataacg tattcccctt tgaacttatt tacgaatttt caagaagctg
    29761 cagctaactt ttccgagacc ccgattatct ttgatgagcc actttcagct ttcccagaat
    29821 taggacttga aacaacttac aaaaaatgct gcgaaagtgt gttgaaacgg gcttatcaat
    29881 tggctcatct tggagtgaaa tccggagaca aagttattat ttataagagt tccgcttttg
    29941 acacatacct tctagctgtt tctgtgtctt accttggtgc agtgcctgtc atgacttctt
    30001 atcatctacc aacaacaaca atggaagtat ttatcgatcg tttagaagac cctttcattt
    30061 tatttgatga tgagacaaaa aagcgagtga gagaaatttc aaatggaaca aaatcaaaac
    30121 agattcctat tctttattta atggaacaac ctgctttgtc tgtttctcaa tcatttttag
    30181 acaaaaatga aatttcttat atgacccata cttctggtac aactggtatc cctaaactta
    30241 tttgtcattc tgctcattct atgggatggc ggacgaaatg gcaaaaaaca gttttcacaa
    30301 aaatttcgga aaagaaatta atcgcttttc acatctctcc agtgcattcc agattcaata
    30361 ttggtatctc ttctttgatg tccatgggat ttcctatgat gcctttagca aacgcacaaa
    30421 gttcaaaagt tgttcatatg ttggaagctc accggccaat tgcactagag acccatccga
    30481 ataactttgt tcagtggcgt tttactgcta aggagcatcc agaagctttt tcgggtatcc
    30541 gatactatca ctccactttt gatgctataa acaaccagac aatgaagaca tttttgcgaa
    30601 cgtcgatggc acaggatgcg gtatttcttc aagtatatgg ccaaagtgaa tgcggaccaa
    30661 tgattcttaa ggctcataca ctagagagtt tgaaaacaag tgatgcaaga gatatgggcg
    30721 ttggactgga agacatgaca agcgctcgga ttacagattc agttgggaat gtcctacctg
    30781 aaaacacaga tggtcatata caattactgt ctaaaggacg ggctttgact tattacaagg
    30841 aagatgcacg gttccaggaa aatgtttatg gcgattggtg ggatagcgga gattacggtt
    30901 ttatggataa gcatggccac ctatttttga aagatcggca agtggatttg atcgaaacga
    30961 tcaatagtac attagctatt gaagactttt tattagattc gttagatttt ttggcagaag
    31021 tagtgattgt aagggataaa aatcattctc cacaaccgat tattgcttta gctcctgata
    31081 aagaaatgga ttggaatcga tggtgggagc aagtccatga acttcctcgc ttgaacgtcc
    31141 ctatcatccg tgattttgat gcaatcccgc gaacagctac aatgaaagtg caacggcttc
    31201 aaatcgagaa agaattaaaa tcacaaaagt cctaactatt taaggaaaga aagatccatt
    31261 ttggtctttc ttttcttttt gtttttttaa attggatgag ataaaaatat gccaattggc
    31321 tgtttttctt ttttgaaaat ttcgttatac tcttattcat ggaggaaaat gttatgaaaa
    31381 gaatcttgac aattggcggt tctgatccat ttgctggtgg aggaatccaa acagatttaa
    31441 aaacttttga gaattttggt ctattcggac taagcgcctt gacttctata ggggcactag
    31501 atattaatga gcgatttatg ctggaatcta tatctttgga attgcttaaa cgacagttag
    31561 tttcgattga taaaatgact tcattagatg gtatcaaaat tgggttattg aattcaagtg
    31621 aagcaatcat ggttgttcga gacttcataa aaacaaaaca aaatatccca atcattttag
    31681 accctgtttt ggcattcaaa gaaactgaag ctgtgatcaa tcaattgtat atttcgcagc
    31741 tcatcgaaga actttttcca cttgttacga tgattacgcc taatttggca gaagctgctt
    31801 tactttctgg tcaagctctt ccctcttcgt taacagaaat gatccatctc gctaaagaac
    31861 tcactgcttc aggaacaaaa aacattgtga tcaaaggcgg cacaaggatg gctggagatg
    31921 aagctgtgga tcttctctat tcaattgatc attatgaggt attttctcat aaaaaaatcg
    31981 acactacaac agtaaacggg gccggttgtg ccttttcttc tgcaataaca gcgaatcttg
    32041 tgttaggggc agattttacc aaagcagtag cagaaagtaa aaaatttgtt gcccattgta
    32101 tttctaatgg cgtgctgatg aacgatcata ccggaagtgt ctggtctggc ggtattcaaa
    32161 aaggaggaat gagaaatgaa aactaagcaa ttaacgatct atgctatgct gattgcgttg
    32221 acagttgccc tttcattaac aattttgatc cctgtaccgg ctacgaatgg atttgtgaca
    32281 ttatgcgagg ccgggatcta taccgctgct tttctttatg gtccaacggg tggattagtt
    32341 gttggtgctt ccagtggtct attgatcgat ttgatttcag gatatccgca gtgggcagtt
    32401 ttttcattag tgatccacgg gttacaagga tatgttgctg gttctttcag caaatcttct
    32461 actcgtatgt ggggattagg gcttttatta ggaagcttag ttatgatcat cggctatggt
    32521 atcgccggtt ggattttata tgattggccg gctggagtgg cttctatacc aggaaacatc
    32581 ttccaaaatc tgattggaat gggacttgcc tttcctataa ctgcaagtct tcaacgtatt
    32641 caagcacgga agcaatatta attgaaaaag aaggttttag aaaatgaagt tgtcagaaaa
    32701 agaattaaaa gaccaattga ctgaaatagt taatgacata ttggctgagg cacacttgaa
    32761 aaaaggtgat ctttttgttt taggatgcag cacaagcgaa gtcgttggag gacatattgg
    32821 aaaaaattcc agtgcggaag ttggtcaatg gatcatccgt acgttaaaag agttgttgga
    32881 tcctaaagaa attgcgctag ctgtccaagg ttgtgaacat ttgaaccgag cattagtagt
    32941 agaacgaaca gtggcagaag caaaaaattt cgaaattgtc tctgttgttc ctgcactaca
    33001 tgctggaggt gcttgttctg ttgctgcttt tgaccagttc aatgatcctg tcgaagtgga
    33061 acacgtagtt ggacaagccg gtatcgatat cggtgacaca tcaatcggta tgcatatcaa
    33121 gcatgtccaa gtacctgtca gacctcgttt gaaaaccctt ggacaagctc acgtgacagc
    33181 ccttcgctct cgtcctaaat atatcggtgg tcctagagcg aattattgaa atgagtaatt
    33241 gacagagcaa tctgaaaaac ttcctcgcaa agtccaacta atgaacttta acgaggaagt
    33301 tttacttgtt tgttttatat aaccgagctt cataaggtgc tagtatgcct ttagcttcaa
    33361 attctccgct agaggaattt gacaagagta atgtccagga ctgatctgct tcttttggaa
    33421 gttcatagtc agcaagtgat tctgttaagt ttaccataat aagatattgt tcatcttcta
    33481 aatatctttc atagacataa agttgtggat gttcatgaag atattcttta taagaaccgt
    33541 atatcagacc tttattggtt tgtctaatgc ggatcatgtt cttatagaat tgcaggaccg
    33601 actctggttc atattcttgt tgttctacat tgatcgtttt ggtatttgga ttagtgatca
    33661 gccaaggttc atgtgtagaa aaaccagcat attgttccga agtccattgc atgggtgtcc
    33721 tgctgttgtc tctcgttgtt tcacgaatga tatccaatgc ttcttctctt gtcttacctt
    33781 ccgcaagcag ccttttataa agtcttttcg aatctactgc atcaacttga tcgatcgatt
    33841 caaagggcat attcgtcatt ccgatttcct gtccttgata aataaatggc gtaccttgca
    33901 aaaagaaata catcatagcg attgcttttg cagacatagc ccaaaaatcg ggacgagtat
    33961 ctccaaacac tgaaacggca cgaggaacat catggttttc catatataaa gcgttccatc
    34021 cgataccatc caatgaagtt tgccaagcgc ttaatgcatg tttcaattta aggacatcta
    34081 attgcccttc tttttcttgc tgccagatat ggatatgatc aaattcgaat atcatatcga
    34141 aataaccgtc tttccctacc cattgtggtc cttcttctgc agtgacacca cttgcttctc
    34201 cgacagtcat gatatcgtac tcttcaaaaa catgtttcaa atcggtcaaa tgttcttcga
    34261 ttcctgagac attttgaaag ggtgagaaag ggttctctgt ggcttttact gaatattcat
    34321 ctttttttac atgagaaatc gcatctaaac gaaatccatc tatcccttta tccaaccacc
    34381 atcggatcat attgaatagt tcttctttca atttctcgct ttcccaattt aagtctggtt
    34441 gttcttttgc aaaaacatgc agataatact gtccagtttc atgagaatac tcccaagcag
    34501 aaccgccgaa aatcgatgtc caattattcg gttctttgcc atctaccccg tcgacccaaa
    34561 tgtaataatc gcgatacggg ctttctttag attttttcga ttcttcaaac cattgatgct
    34621 gatccgaact atggttgatg acaagatcca taatcacttt gatccctaat tcatgtgctt
    34681 cttttagcaa taaatcaaaa tcttccatcg ttccgaatct ctcttctata tcttgatagt
    34741 cacttacgtc ataaccatta tcgacaaatg gagattgata gatcggattg atccagataa
    34801 agccgatacc aagatctttc aaataattaa gtttttcacg gatcccattg atgtctcctt
    34861 gaccatcgcc attgctatct ttgaaactag caggatagat ttgatagcct actgcttctt
    34921 tccaccattt ttgttcttgt atcatatcgt ttcactcctt taacggtccc tcttgattat
    34981 aaccgattct attttagaag tatccttgtt accggtaact agaaacgaaa agctcaacga
    35041 atctgctaag tgcgttcgtt gagctttatt ttatcataga tagcgggcaa tcagttgaat
    35101 catttgcttg ggaaattcat tcaagtcagt aatatctaca aaacgacttt caccgtagat
    35161 cgacttgatt tcttctttgt cttggccaat agctgcggag acaaatagga ttccttgacg
    35221 ttcatattct ttcaaaacag actggatatc ttcttttgct tttttgcctg tataatccgg
    35281 caatgctttt ggctgaccgt cactaatatt aagcaacagt ttggttgttg cggattgtct
    35341 gtttaatttt tctgctgcta aacgaagtgc agcaccatca cgattgtttt gccttggttt
    35401 catagtgact aatttttcat ttaaccattg aaatccgtct tcaaattctt tataagaaaa
    35461 caaagaagtc ttttctcttg acgaacggtc tgctgtatct ccgtaaatca acaatgggat
    35521 atcgactttc ttagaaaatt cggcaatggc aatcgctgct ttttttgccg cttcgatccg
    35581 atcatcccgt atcattgacc cagattcatc gatccgtaca gctaccgcta aagaaggttg
    35641 ctcatgtggc gggttctttt tgtcaaaatt tctcaaatca ccatatgcta ctttgcttgc
    35701 attgaaccgc tgaccttcgt attttccttt ttggtacgtc tctgtttgtt cattatccag
    35761 taactctaaa atttgccggc taagtgattc tactattggc attacttgca tgtgtagctc
    35821 acgtgcttcc ggcgtttttc cttggaaagc tggtcggtga acgatgagac cttctttttc
    35881 atgaatcgtt tccttcatga tttgtcgcgc ttctttattc agttgcttct tgatttcctt
    35941 atcatgtgct tccatgtcag aagcagacat ttcttgagaa tcatctcctg tttgttgttc
    36001 tttttgattt tttccttcga tatcgctact gcgttctttt tgcatttgag gaggaatctc
    36061 gtttttttct attgtttctt cttgtttctc ttctccctca tttggttctt cagcagacaa
    36121 cgatttcttt tcatctaagc gcagaatttc ttcagcattt tcagtgatgt ttcgttcatt
    36181 tgcttcttcg gcgctaatgg ttctttcttt tgtatgctca gattgaggat gaccccattt
    36241 ttcttttctc aatatgtcct gaagttccag tagcaatcca ctgtcagaca aagcttgttc
    36301 aagaattgcc aattcatctg aatcagtgga taatttatac aaaacttttg gataaatcga
    36361 ctggagtaaa tcttgtcctt gcttataggt atttgcccaa taaaaataag aacgcattcc
    36421 tgctacacct ttgatggcgt tagcttttgc agtttcatcc aacaaacgga taatctctgc
    36481 catctttaag agaagttctt gtttttggat catagttttc gccatcgcac gttctgccat
    36541 gacttctaag gcaggaagat ccattttttc cgcatgttgc atccgatctc ttaaagattc
    36601 atttaatggg cgatttcctt ggtaatttcg atttgtagtg atcacaatga cgcaatctgg
    36661 atggcgacga atgattcctg tcggtaaatt caacatccca tttggttcga gcgctgagtt
    36721 aagtgccaca agaacagagg catctcggat gacagtcggc tcttgaatct ctaataaata
    36781 gcctttttca atcgctcgaa cgatttcaga agggtaatag ctgtaatgga ttgcatctgg
    36841 ataatcagct tcgatccttt gaactagctc tgctaatttt tctttagcag aaaaaggatc
    36901 aatgccgtaa tggttctgga tcagtgtcag tacagcttca agtgtatctg tttggtaaat
    36961 agcttctagt aattcttggt cttgttcctt attagaatct actacaggta ataaggctcc
    37021 gaaaacatct gatttgtcca tatctgcaaa acaggtcact tttgtatagg gaagttgcag
    37081 atcagcagat agtgctttgg ctaattgtgt cttccccgac ccggcatctc cttccaaaag
    37141 tacgttactg attttcattt caggatcttg ccaattccct ttgatttcgg aggcgatccg
    37201 ccattcttct gcacttgtcc gatggctttt cggtttcttc cagatcattt gcttttctag
    37261 ccgtgaaaag gttcggtttt ctgttagtga gaaattctcc atgcttctct tccccttttg
    37321 atcatctctg tctattaata tcctagctca tctaaaagac gttttaaaat acggaatcgt
    37381 tccccaatca gttctccgtc tttttgtagt gtatcgtaat acaaaatgat gtcttcatcg
    37441 atctttggat ttttggtatc tacttctacc gtcattcggt tcccttgtaa tccaatgatg
    37501 tctacgactg gattttctgg atcataaaat ttttcataac gataagcatc ttggaagtat
    37561 aaacttcctt gcgcagctaa gatcgctaaa tctaaaatac gtgtgattgg taattcttcc
    37621 gactgtcgtg accatttttc tccagtatgt cgccatacct tgcctgagat atcgactttt
    37681 ccacgatcat tccactgagc aaggcccagt gaaagccctt ttgcatccat atttaatgca
    37741 tttcttccat caactttatc atagtcttct acaacgatta ctggtttatg ttttaaattt
    37801 gttggtattt ccattatttt aactcctcat ccttttattt ttagtaaata agtaaattag
    37861 tagtttactc atttactaaa ctatatgcga cattatagag gattgaagtg aggattgcaa
    37921 agaaaaagag cttcattgat agaaataaaa acaccatctc gttcttttac acgctcatta
    37981 gtaacatgta gaaagtccaa gatgatgttg gaat
//
LOCUS       DACCVH010000016        37386 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.016, whole genome shotgun sequence.
ACCESSION   DACCVH010000016 DACCVH010000000
VERSION     DACCVH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.016"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..616
                     /locus_tag="IVV98_000910"
     CDS             <1..616
                     /locus_tag="IVV98_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP7806584.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="IVV98_000911"
     CDS             613..1386
                     /locus_tag="IVV98_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP7806585.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="IVV98_000912"
     CDS             1383..1781
                     /locus_tag="IVV98_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP7806586.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="IVV98_000913"
     CDS             1966..2637
                     /locus_tag="IVV98_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806587.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="IVV98_000914"
     CDS             2696..3136
                     /locus_tag="IVV98_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806588.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="IVV98_000915"
     CDS             3148..3816
                     /locus_tag="IVV98_000915"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP7806589.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="IVV98_000916"
     CDS             3880..4503
                     /locus_tag="IVV98_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP7806590.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="IVV98_000917"
     CDS             4559..4945
                     /locus_tag="IVV98_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP7806591.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="IVV98_000918"
     CDS             5158..6549
                     /locus_tag="IVV98_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP7806592.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="IVV98_000919"
     CDS             7160..7528
                     /locus_tag="IVV98_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7806593.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="IVV98_000920"
     CDS             7708..8649
                     /locus_tag="IVV98_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP7806594.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="IVV98_000921"
     CDS             8718..9449
                     /locus_tag="IVV98_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP7806595.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="IVV98_000922"
     CDS             9593..11773
                     /locus_tag="IVV98_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP7806596.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="IVV98_000923"
     CDS             11793..12275
                     /locus_tag="IVV98_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP7806597.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="IVV98_000924"
     CDS             12291..13052
                     /locus_tag="IVV98_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP7806598.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="IVV98_000925"
     CDS             13183..14517
                     /locus_tag="IVV98_000925"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP7806599.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="IVV98_000926"
     CDS             14824..15309
                     /locus_tag="IVV98_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP7806600.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="IVV98_000927"
     CDS             15302..15985
                     /locus_tag="IVV98_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP7806601.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="IVV98_000928"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="IVV98_000928"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP7806602.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="IVV98_000929"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="IVV98_000929"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP7806603.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="IVV98_000930"
     CDS             19601..20230
                     /locus_tag="IVV98_000930"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP7806604.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="IVV98_000931"
     CDS             20282..20614
                     /locus_tag="IVV98_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP7806605.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="IVV98_000932"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="IVV98_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP7806606.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="IVV98_000933"
     CDS             21440..22813
                     /locus_tag="IVV98_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP7806607.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="IVV98_000934"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="IVV98_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP7806608.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="IVV98_000935"
     CDS             23868..24308
                     /locus_tag="IVV98_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP7806609.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="IVV98_000936"
     CDS             24452..25153
                     /locus_tag="IVV98_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP7806610.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="IVV98_000937"
     CDS             25150..26271
                     /locus_tag="IVV98_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP7806611.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="IVV98_000938"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="IVV98_000938"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP7806612.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="IVV98_000939"
     CDS             27650..28558
                     /locus_tag="IVV98_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP7806613.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="IVV98_000940"
     CDS             28593..28865
                     /locus_tag="IVV98_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP7806614.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="IVV98_000941"
     CDS             28876..29922
                     /locus_tag="IVV98_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP7806615.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30173..32782
                     /gene="clpB"
                     /locus_tag="IVV98_000942"
     CDS             30173..32782
                     /gene="clpB"
                     /locus_tag="IVV98_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP7806616.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32933..33604)
                     /locus_tag="IVV98_000943"
     CDS             complement(32933..33604)
                     /locus_tag="IVV98_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806617.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(33597..34091)
                     /locus_tag="IVV98_000944"
     CDS             complement(33597..34091)
                     /locus_tag="IVV98_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP7806618.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34111..35331)
                     /locus_tag="IVV98_000945"
     CDS             complement(34111..35331)
                     /locus_tag="IVV98_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806619.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35478..37313
                     /gene="lepA"
                     /locus_tag="IVV98_000946"
     CDS             35478..37313
                     /gene="lepA"
                     /locus_tag="IVV98_000946"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP7806620.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT        12416 a         6551 c         8101 g        10318 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa aacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagcccaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
    30001 tttttttata tacatacaat caattttgtt tttttaagat ttatataagt cgagaaaaaa
    30061 agtcaaaaaa ctatgtgtat attttgacca aaattgacca aagcgatata atagtttttg
    30121 taaagatcaa agaaataagt gatcttacct ttaattagga gggtatacct gtatgaatat
    30181 tgagaaaatg actacgacgc ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac
    30241 tcgaaaacat caagatatcg acattgccca tgtatggaaa atctttttac aatctaatca
    30301 ttttggtcga aatttctata cggatgccgg attggatgtc gaatcttttg aacatgaaat
    30361 tgatcgtcta ctggatgagt atccagttgt ttctggtgga aacgtccaat atggacaaaa
    30421 cctcagccag aatttctttc gattattgaa tgaagcagac caaatacgtg aaagcttcgg
    30481 cgacgagttt ctttcaacgg aagtcgttat tttagcgttg atgaaattaa aaaattatcc
    30541 gttaactgtt tatttgaata aaaacggatt atctgaaaaa gaattgcgta aaaacatcga
    30601 agagatgaga ggaggagaaa gagtgacctc acaaaaccaa gaagaacaat acaaagcatt
    30661 agaaaaatac ggcgttgatt tagtacagca agtcaaaagc ggaaaaatgg atccaatcat
    30721 cggtcgtgat gaagaaatcc gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa
    30781 tcctgttctg ataggagaac ccggtgtagg gaaaacggca atcgttgaag ggcttgctca
    30841 acgtatcgta cgcaaagatg tgcctgaaaa tttaaaagat aaaacgattt tttcattaga
    30901 tatgggtgca ttgatcgctg gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc
    30961 agtcttgaaa gaagtcaaaa aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca
    31021 caatatcgta ggggcaggaa aaacagaagg aagtatggat gccggaaatc tgttgaaacc
    31081 aatgcttgct cgcggtgaat tacatttgat cggtgccaca actttagatg agtaccgtca
    31141 atatatggaa aaagacaaag cgttggaacg tcgctttcaa aaggtattag tcaaagaacc
    31201 aacagtggaa gatacgatca gtattctgcg tggattaaaa gaacgttttg agatccacca
    31261 tggtgttaac atccatgaca acgcattagt agcagcagct actttatctg accgttatat
    31321 tactgatcgg ttcttaccgg acaaagcaat cgatttgatc gatgaagcca gtgcaacgat
    31381 tcgggtagaa atgaactcta tgccaacgga attagatcaa gttactagac gtttgatgca
    31441 gttggaaatc gaagaagctg cactgaaaaa agaatcagat gatgcaagta aaaaacgctt
    31501 gaaaaatttg caagaagaat tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca
    31561 gtgggaaaca gaaaaagaag aagtcaattc tgtttcagca aaacgtgctg aaatcgataa
    31621 agcaaaacac gaattagaag atgcagaaaa taactatgat ttagaacgcg ctgctgtatt
    31681 gcgtcatggt acgatacctc aattagaaaa agaattgaag gaattagaag ctaaagcaaa
    31741 agacagcgag attaagatgg ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt
    31801 tggcagatta acgggtatcc ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat
    31861 taaattgaat gaaacacttc ataaacgagt gattggtcaa gatgaagcag ttgatgcggt
    31921 cagtgacgcg gtaattcgtt cacgggctgg attgcaagac ccaaatcgtc ctctaggttc
    31981 tttccttttc ctaggaccaa ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga
    32041 gaacttgttt gactcagaag atcatatggt acggatcgat atgagtgaat atatggaaaa
    32101 acatgctgtg tctcgtctag tcggagctcc tccaggctat gtaggttacg aagaaggtgg
    32161 tcaattaacg gaagctgtca gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga
    32221 aaaagcgcat cccgatgtct tcaatatctt gttacaagtc ctagatgacg gacgcttgac
    32281 tgattcaaaa gggcgagtag tagatttcaa aaatacggtt ctgatcatga ccagcaatat
    32341 cggttcacag ttactgctgg aaggcgtgac tgctgatgga acgattccag aagcagtggc
    32401 tgaacaagtc aacacgctat tacgtggaaa cttcaaacca gaattcttga accgaatcga
    32461 cgacacgatt ttatttacac cattgagcct agacaacgtg aaaggaatcg ttgacaaaat
    32521 ggtggcgcaa ttggcacaac gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga
    32581 agccaaaacg tggattgctg aaaatgctta tgaaccagca tatggtgcaa gaccattgaa
    32641 acgatttatc actaaggaag tagaaacacc actagctaaa gaaatcgttg caggacatgt
    32701 tatgcctaaa tcaaaagtaa cgattacttt acttgatgga caacttcatt tcaaaacaga
    32761 agagctagaa gaaatcgtct aatcttccat tgagactata aaagaaaaaa ggggtctgac
    32821 acaactagtg tcagacctcc ttttttcaaa taaacagtgt tccagaagta gtttcttcga
    32881 aaaataagcc gaaatttctt gaagctgccc gcttctgtca caacctcttt tattaggtat
    32941 ttttcacttt ttctaattta taactttcaa agtaacgctc atctttttta ctttgagacc
    33001 atgcaaacaa tcccattaag gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat
    33061 ccatcaatgc tgctcgtccg acaaacagtg tgccatcaga agcagcaaaa cgttgaagat
    33121 tcatgcctaa gaactggtcg cataagaatt cccagaactc ccaaaacacg ccgcaaagtc
    33181 cagcaaacgc aaagccgaat aagaggaaca accaaggact ggtttttgat atctcagcat
    33241 ctttcatcaa gtaaccaatc aatccatagc caagagctgt caggaccatt ggactcaccg
    33301 catgtaagat tttgtcccaa aaagagatga tactgatcaa atgcatccct gtgcctaaaa
    33361 agacagagat gaacaagaaa aaccagtaaa acaaaacgat tgctgctggt attttaagtt
    33421 tgaaaacttt caaaatgact tgtggcatga aaatcaatgc aatccctaat aaagattcca
    33481 cgataaatgt gattccttga gaagtcgaat atttttgtgt gataaattca taaaaattat
    33541 agcagacaac gaatacacca aaagcaagta aagctatttg cacctttttg atttctttaa
    33601 tcactgaaag tccctccatc taaaaatctt tttacttctg aaagcaactc aatttctgaa
    33661 gaaaccactt ttccgttcaa tttgatcaaa cctattgtat ataagttcag gtagtgaaat
    33721 tgattttcag ctgtttcttg tagtgcagcg atttttttcg ggtgggttcc gccttgctgt
    33781 cgagtatcag tatataagcc gatcactggg atgcctttcg cataagccac accgatttcc
    33841 gatgctaccc cggcatcgat cgtcagccca tctagtaaag caatcattaa atcactagcc
    33901 aacacttttt ctgtgtcagc aagagcaatc attcgactgt ctgcataagc agttttgtca
    33961 ttgattgctt cattttcttg aggaagatag atcgaaagct cagaagagag ctctctgatt
    34021 tctttaacta actgttggtt atataacaaa tcacttttag caaacattgg tgcggcaaaa
    34081 taaattttca tctaaacatc atccttttta tcaaaaataa tcgctaaagt aagcttccat
    34141 gtttggaatg atacgctcta gtgacttcag tgtttcttca tctgtttcta accgttcgat
    34201 tcttgccaaa taagaagcac ggcgataatt catcatcaag caagtcaatg tttggatatc
    34261 cagtcgaacg gattttccta taggttcatt taagacacgg acttgtccct gttcatccca
    34321 tgttaaagcg aagacaccat tattccaagg agcgacagga tcttcaatga tgaaatgaaa
    34381 agcatcagct gttccaacaa acggaaaccg ttgaaggaat tcttttacat caacgatccg
    34441 agccataaaa tatggttcga tctgctcttt gatctgacta tcttcaatca aaaatgctaa
    34501 aggctcattt ttataaatat ctccatgtac ccagtagatc atggaaaaat gtgcggaaat
    34561 aaagttccat aagccatttc gagcttcttg atcaagatag aacatttctt ttacgtgaaa
    34621 tatttcttca gctacccagt agaacagaac acctcttggt tcatggttgc tatcgtagta
    34681 gacagcggct gtgcgctcat cttcattttc gaaacgccaa tactcttccc aatgaaaatc
    34741 actgcggaat aaagcaccat ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc
    34801 tggatgatca actggtaatc gctcaaccat accacttact gggatttgtt taggtagctg
    34861 tgtatctctg attttaaagg aaagtttatc agacatgatt tcccatcctt tacgccgata
    34921 gtaggggata ctgtaaggat acaaataaga gatccattgc ttattcttgc gcatattatc
    34981 caatgcaacg ataattagat cttgcatcaa tccatggtta gcatattctg gataagttcc
    35041 aactccagtc acaccaccca ttttataacg tgcaccgtga atattgactt cacaaggata
    35101 gatagcgatt tgagagatca gtttattttc gtggaaccat ccgaacactt tcgatacttc
    35161 caaaatcggt tttttggaac ggataaaagc tcgtttattc tcaaacccgc tttcctcgat
    35221 gtctgcttca gtcacttgga acacatagga aagcaattca ttgaattgat cgatatgttc
    35281 ttgagtgacc ggttttaatt caagattttc tctaaaatct ttttgatcca ttttttcatc
    35341 tccatttatt agcttgataa cagtatagca aaattctaca aaaaaaactt ctatagctga
    35401 ctaattaaaa actctttaaa ttactgcttt tcgttggtat aatggaaagt gctgattata
    35461 tgaaaagagg agacgctatg gatataaaga aaatgaaaga acgccaagag cagattcgta
    35521 atttttcgat catcgctcat atcgaccatg ggaaatctac attggccgat cgtattttag
    35581 aaatgacgca cactgtgacg tctcgcgaaa tgcaagatca gctgttagac tcgatggatt
    35641 tggaacgtga acgtggaatc acgattaaat taaatgctgt agaactcaat tacacagcga
    35701 aaaatggaga aacatatatc tttcacttga ttgacacccc agggcacgtc gacttcacct
    35761 atgaagtctc tcgaagcctt gctgcctgtg agggtgccgt tttagtggtc gatgcagcac
    35821 aaggaatcga agcacaaaca ttggccaatg tttatttagc gttagacaat gatttggaga
    35881 tcctgccagt catcaataaa atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag
    35941 aaatcgaaga cgtaatcgga atcgatgcta gtgaagctgt attagccagt gccaaatcag
    36001 ggattgggat tgaagatatt ctcgagcaga tcgtggaata tgttcctgca ccaagtggag
    36061 acttagatgc accgctaaaa gctttgatct ttgactctat ttatgatagt taccgcggtg
    36121 ttgttctaaa tgtccggatc acggacggta tggtcaaacc cggagacaaa atcaaactga
    36181 tgagtaatgg caaaacattt gatgttacag aggtcggggt cttctcgcca aaagcagttg
    36241 ctagagactt tttgatggtc ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc
    36301 aagatacacg agtaggggat acagtaacgt tagcagacaa tcctgccgct gaagctttac
    36361 caggttaccg aaaaatgaat ccgatggttt attgtggtct ttatccaatt gatacttctc
    36421 gttacaacga tttgcgggaa gctttagaaa aactgcaatt gaatgatgct gctttacaat
    36481 tcgaaccaga aacctctcaa gcattaggtt ttgggttccg ctgtggattc ctcggacttc
    36541 ttcatatgga tgtcgtccaa gaacgcttgg aacgggaatt caatctagaa ttgatcacga
    36601 ctgcaccatc cgttatttac catgttaata aaacggatgg tacgactgct acagtagata
    36661 acccggcaga ttttcctgaa cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag
    36721 cacagatcat ggtcccaaat gattttgtcg gtgcagtaat ggaactttct caacgaaaac
    36781 ggggagaatt cattacgatg gattatttag atgattaccg agtaaatgtc gtctataata
    36841 ttccgctttc tgaaattgtc tttgactttt tcgacaaatt gaaatcaagc acgaaaggct
    36901 atgcctcatt ggattatgaa atgtctggtt atcaaaaaag caagttagtg aagatggaca
    36961 tcttgctgaa tggagaaaaa gtcgatgcat taagctttat cgttcaccga gactttgcct
    37021 atgaacgtgg aaaagcaatc gttgaaaaac tgaaaaaact aatcccacgc caacaatttg
    37081 aggtgccaat ccaagcagct attggacaaa aaatcgttgc ccgttcagac atcaaagcct
    37141 tgcgtaaaaa cgtcttggct aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct
    37201 tagagaaaca aaaagaaggg aagaagcgga tgaaacaaat cggctccgtc gaagttccgc
    37261 aagaagcctt catggccgtt ctgaaaatgg acgaggacga accgaagaaa tagcaagggt
    37321 ttgtttgaaa acagtgtaaa aaataaacca tgtttacatg gatttgccac cggtttgcca
    37381 ccggtg
//
LOCUS       DACCVH010000017        37135 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.017, whole genome shotgun sequence.
ACCESSION   DACCVH010000017 DACCVH010000000
VERSION     DACCVH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.017"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(141..416)
                     /locus_tag="IVV98_000947"
     CDS             complement(141..416)
                     /locus_tag="IVV98_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP7806621.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /locus_tag="IVV98_000948"
     CDS             complement(659..1969)
                     /locus_tag="IVV98_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP7806622.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IVV98_000949"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="IVV98_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP7806623.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="IVV98_000950"
     CDS             complement(3515..4195)
                     /locus_tag="IVV98_000950"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP7806624.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="IVV98_000951"
     CDS             complement(4244..4879)
                     /locus_tag="IVV98_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7806625.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="IVV98_000952"
     CDS             complement(4945..6348)
                     /locus_tag="IVV98_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP7806626.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="IVV98_000953"
     CDS             complement(6335..7366)
                     /locus_tag="IVV98_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806627.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="IVV98_000954"
     CDS             7397..7618
                     /locus_tag="IVV98_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP7806628.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="IVV98_000955"
     CDS             complement(7783..8520)
                     /locus_tag="IVV98_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP7806629.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8673..10013)
                     /locus_tag="IVV98_000956"
     CDS             complement(8673..10013)
                     /locus_tag="IVV98_000956"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP7806630.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10250..11773)
                     /locus_tag="IVV98_000957"
     CDS             complement(10250..11773)
                     /locus_tag="IVV98_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP7806631.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12151..12762)
                     /locus_tag="IVV98_000958"
     CDS             complement(12151..12762)
                     /locus_tag="IVV98_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7806632.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12885..13010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13092..13808)
                     /locus_tag="IVV98_000959"
     CDS             complement(13092..13808)
                     /locus_tag="IVV98_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP7806633.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IVV98_000960"
     CDS             complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="IVV98_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP7806634.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14367..15164)
                     /locus_tag="IVV98_000961"
     CDS             complement(14367..15164)
                     /locus_tag="IVV98_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP7806635.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15134..15505)
                     /locus_tag="IVV98_000962"
     CDS             complement(15134..15505)
                     /locus_tag="IVV98_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP7806636.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IVV98_000963"
     CDS             complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="IVV98_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP7806637.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(16507..16980)
                     /locus_tag="IVV98_000964"
     CDS             complement(16507..16980)
                     /locus_tag="IVV98_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7806638.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(17085..17948)
                     /locus_tag="IVV98_000965"
     CDS             complement(17085..17948)
                     /locus_tag="IVV98_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7806639.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(18144..20243)
                     /locus_tag="IVV98_000966"
     CDS             complement(18144..20243)
                     /locus_tag="IVV98_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP7806640.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(20463..21572)
                     /gene="rpoD"
                     /locus_tag="IVV98_000967"
     CDS             complement(20463..21572)
                     /gene="rpoD"
                     /locus_tag="IVV98_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP7806641.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(21596..23437)
                     /locus_tag="IVV98_000968"
     CDS             complement(21596..23437)
                     /locus_tag="IVV98_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP7806642.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(23619..26012)
                     /locus_tag="IVV98_000969"
     CDS             complement(23619..26012)
                     /locus_tag="IVV98_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7806643.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(26119..26979)
                     /locus_tag="IVV98_000970"
     CDS             complement(26119..26979)
                     /locus_tag="IVV98_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP7806644.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(27038..27559)
                     /locus_tag="IVV98_000971"
     CDS             complement(27038..27559)
                     /locus_tag="IVV98_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP7806645.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            27879..28598
                     /locus_tag="IVV98_000972"
     CDS             27879..28598
                     /locus_tag="IVV98_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7806646.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            28624..31215
                     /gene="mprF"
                     /locus_tag="IVV98_000973"
     CDS             28624..31215
                     /gene="mprF"
                     /locus_tag="IVV98_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP7806647.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(31403..32590)
                     /gene="tuf"
                     /locus_tag="IVV98_000974"
     CDS             complement(31403..32590)
                     /gene="tuf"
                     /locus_tag="IVV98_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP7806648.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            32958..33314
                     /locus_tag="IVV98_000975"
     CDS             32958..33314
                     /locus_tag="IVV98_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7806649.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(33555..34559)
                     /locus_tag="IVV98_000976"
     CDS             complement(33555..34559)
                     /locus_tag="IVV98_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP7806650.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            34725..35576
                     /locus_tag="IVV98_000977"
     CDS             34725..35576
                     /locus_tag="IVV98_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP7806651.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            35593..35838
                     /locus_tag="IVV98_000978"
     CDS             35593..35838
                     /locus_tag="IVV98_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806652.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            36025..36729
                     /locus_tag="IVV98_000979"
     CDS             36025..36729
                     /locus_tag="IVV98_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806653.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        10488 a         7802 c         6397 g        12448 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtagatagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgttccc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctc
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaaccgctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     8641 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     8701 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     8761 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     8821 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     8881 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     8941 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     9001 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     9061 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     9121 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     9181 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     9241 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     9301 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     9361 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     9421 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     9481 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     9541 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     9601 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     9661 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     9721 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     9781 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     9841 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     9901 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     9961 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
    10021 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
    10081 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
    10141 gaaaaaacac tcactgaatg gagctattga cttatccacg tgcttatcga tagccgttta
    10201 tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt tagaacattg
    10261 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
    10321 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
    10381 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
    10441 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
    10501 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
    10561 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
    10621 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
    10681 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
    10741 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
    10801 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
    10861 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
    10921 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
    10981 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
    11041 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
    11101 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
    11161 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
    11221 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
    11281 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
    11341 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
    11401 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
    11461 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
    11521 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
    11581 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
    11641 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
    11701 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
    11761 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
    11821 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
    11881 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
    11941 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
    12001 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
    12061 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
    12121 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
    12181 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
    12241 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
    12301 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
    12361 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
    12421 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
    12481 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
    12541 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
    12601 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
    12661 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
    12721 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
    12781 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
    12841 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
    12901 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
    12961 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
    13021 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
    13081 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
    13141 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
    13201 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
    13261 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
    13321 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
    13381 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
    13441 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
    13501 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
    13561 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
    13621 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
    13681 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
    13741 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
    13801 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
    13861 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
    13921 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
    13981 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
    14041 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
    14101 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
    14161 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
    14221 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
    14281 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
    14341 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
    14401 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
    14461 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
    14521 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
    14581 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
    14641 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
    14701 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
    14761 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
    14821 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
    14881 tctgtgacga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
    14941 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    15001 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    15061 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    15121 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    15181 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    15241 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    15301 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    15361 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    15421 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    15481 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    15541 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    15601 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    15661 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    15721 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    15781 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    15841 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    15901 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    15961 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    16021 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    16081 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    16141 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    16201 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    16261 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    16321 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    16381 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    16441 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    16501 agacactcag acggactggt ttcttttttc tttttcatag cattcctgac agattccatg
    16561 gaacgttagc cgatgatctt ttactaaaaa atgataacgt tcttctacta cttgctccac
    16621 ttcaagtaaa agatcctctt ctacttcctc gatcgtgccg cagttcaagc atagtaaatg
    16681 atgatggaaa tgtttggcgc cttcttttct caaatcataa cgggctaatc catcattaaa
    16741 acttacttta tcgacaattt tcaattctgt caagatttca agggttcgat aaacagtagc
    16801 aagtccaatt tccggactct tttttttcac taaaaagaag atttcttctg cagataaatg
    16861 ctctttctca ttttccaaaa gcacaagcag agtagcttct ctttgcggtg tcagcttaaa
    16921 ccccgcttca tgtagctgct gttttgtttt tttcatcgcc gaaatagcat tcatgaccat
    16981 ttactcaacc ccaacaattt ataataatta caaataaaaa aagatataac actatgttaa
    17041 ttaaaattat tataagctag ttaagaaaaa catgcaaggg attctcaatt agattttttg
    17101 actagttttg tcacaccgtt ttcttgtgta atcaatcctt gtttcaaaag attacctaat
    17161 gcgcgcttaa atgctccttt gctgatacca aaagctttca tgatttcttc tggatccgat
    17221 ttatctgtaa agttgatttg ctgatctgca gaacgttcta aaatggttaa aatcatttgt
    17281 gcatcatctg atatagcttc atatgctctt ggcttcaatg aaagattcag tacaccgtct
    17341 ggtcggacac caatcactcg accttttatc tgctcgccta gacgaggttc attatatcgt
    17401 tcagaaggat ggataaaccc aagatagaaa tcttccgtta aaacgtacgt acctgttaat
    17461 ttcaagcggt atgctgttcc tatcacatct ttgtttttca tttcttctgt tccatatttg
    17521 cttaaagatt tgaatatttt ttcatctgct aaactgcccc aaatacggtc ttttgcatca
    17581 actctaaggg aaatcatcaa gcgatcccct tttttaggcc atagctctgt cattgtcggc
    17641 aattcatcaa gagatacgac aaagtcttta tctggaagac cgatatcgac aaacgcacct
    17701 aaatcttttc gtgtagcagt aacgattcca aaagcgtaat gaccgatacg gcttttagga
    17761 atttgtgtag tgatccgatt ttcatgtttt tgattttggt aaccgaatcc ttcaactgct
    17821 tcaccgattt tgtgttcacc ttctgatttg cttaagccaa aggtttgtcc gtttttttgg
    17881 acaaagtagt ttttttcatt ttcatcaata ataatacctg taaatatagt tgctaataaa
    17941 tcgttcattt ttttctccct ctatagtgaa aggttttctt aatacatttc tttgctatca
    18001 taacataatg ttatctactt gaatagctga gccttggttt ggaaaggtga aaaaaggagt
    18061 atgacaacag ttgtgtcata ctcccctttt tcgaataaac ggtgttaaac ggcaggctca
    18121 cagcctcttt catttgccta aaattaattg ctcccatttc ctccgaacca tccagtttta
    18181 cagttgatgg ttacgatgta aaatggcaaa gcactttctc caatgccttt catcaatgca
    18241 gattttgttg aagtggcata tagattataa tagccttccc cattttcgat tctggctttt
    18301 tctaatctgt aacctccttc aacgatatat ccacgttgga tacatgtagc aatcactttg
    18361 ctttggacac ctggtgccca cgtccatgct ggattagatg catcggcaat atcacttgct
    18421 ctggcagatt tgattggctg attcgctgag tttgaagagg aaggggtcga ggatgccgct
    18481 tcttgctgtg ctgcttgtgc gaccgcagct tgttgagcgg cttgagctgc agctgctgct
    18541 tgagcggctt gttttgcttg ttcttcagct gcttttttcg cttcttctgc ttttttcttt
    18601 tcctcttctt cttttttctc tttatcagtg agcatcttat ctacttgttt caattgttca
    18661 ttcaactgag cagatagatc tgtatttttc actttttcta ctgcttcttt tgccgtcttg
    18721 tattggtcgc gtgttgctga atccactact tttccgtctt taaagactat agctgttttt
    18781 tctttagctg tttgcaattc agcatattga tttttagctt ctgtttgtgc ttgttgaatc
    18841 aattttccaa aatctgtgtt atccgtttcg attgcttgga tctctttatc tgctttcaac
    18901 ttgatgtcat ctgctagatg atcatcgacg atggcaggtg ctatgaacca ctcattcact
    18961 ttttggatat ctcggatctt agattggata tcttggtaag ttgtttctaa ctctgaatat
    19021 cctttttcat tcttaagact ggataaatca ttttttagtt ttgataaatc ttgatgaatc
    19081 atatctgcac gaataaattg atggtgatca tctgtataaa aggcagcaag tttctcatga
    19141 agttcttcca tttgttgctg tctttttgct tctgctgcta cttcggcttc tactttttga
    19201 tgatggtcat aataagccca gcttcctcca ccgagtagaa gtactgctgc taaaacgaga
    19261 taaggtactt tttttgattt tttcttttgc gctttatctg gatctgtttt ttctaagttt
    19321 gattcttgat gtgttttttc agtatctggc acgattgtta ttgatttcgc ttctgcttca
    19381 aacagcttag gctggttctc ttctttttct atttttgctt caagatcagt accctctttg
    19441 cttacagatt gattttcagc atcggattca ctatttattt catcgggctc tgttgacttt
    19501 ttgtctgtgt tttcgagtat ttcttttttc tctgcttccg gcagtttatt cgttttttcc
    19561 ttttctaatt gtttttcagt aaatacttca gttttttctg tgatatccgt ttttacgtct
    19621 tttattttta ctgtttcttt acctgtggcg ttttctctat cagagtcttt ttcagtttct
    19681 tgttcctttt ctggctctac tttgttttcc tgtgcaattt tttcactgat cattttgagc
    19741 agctctttcg cgtgctcttc ttttgtatct tcacgatgtg ctttgatata agcggatagt
    19801 atcgaatttt cttcctcatt atcgacgatt tctttcagtt cagctactct tcttttttgt
    19861 tttgattcaa gcgtttcttc ttgattcttt cctgattctt ccgaagtctc atgaacagtt
    19921 gctttcttct gttcattttt ctctatatta gttacttgat cgtgagcagg tggttcttcg
    19981 tcttctggtt ctgctttttc gaataattcc attacagatt ctagaggtaa atctttcaat
    20041 tccgaccatt cgattggatc gtttaattct gtatcaggaa agactgcatc ttcagttgat
    20101 ttatcctgca tagctgcatc tgtatttgtt tcttcaattg attcttttat ttgctgatct
    20161 tctgcagtta tttgatgacc gcagtctgga cagatagtat tctgctccat ttttttcgat
    20221 ccgcaatttg gacatttttt catcacttag cgatcggctc ctttactagg tttacgctac
    20281 catttaatct atcatattct atacgtcacg ccaatagctt atttttagga tttacttaaa
    20341 aataatgaat gaatttcctt cctatagaaa aaaaagcttg agactgcgta gtctcaagct
    20401 ttttttcttt taaaataaac caaacagttt tactgatttc tcttctggtc aatagtccac
    20461 gcttattcta agaaatcttt taattgtttt gaacgagaag gatggcgcaa ttttcttaat
    20521 gctttagcct cgatctgacg aatacgttcc cgagtaacac caaatacttt ccctacttct
    20581 tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta agcgaaggac attctcttcc
    20641 cgatcagtca atgtatctag tacatcttcc aattgttctt ttagtaactc ataagctgcg
    20701 tgttctgctg gacttgttgc ttcctggtct tctatgaaat cacctaagtg agagtcatct
    20761 tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg cgattttcaa gatttctcgg
    20821 actttttctg ttggaagatc catttccgca ccgatttctt ctggcgtagg ttctcttcca
    20881 aggtcttgca gcaattgacg ttggatacgt atcaatttat taattgtttc aaccatatga
    20941 actggaatac ggatcgtacg tgcttggtca gcgattgctc gagtgatggc ttgacgaatc
    21001 caccatgtag cataggttga aaacttaaat cctttgcggt agtcaaattt ttcaactgcc
    21061 ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga actgcatgcc tcgtcctaca
    21121 taacgtttag cgatacttac tactaaacga aggtttgctt ctgccagacg ctgtttcgct
    21181 tcttggtcgc cttcttcgat tttcaatgct aacgctactt cttcttccgc agttaaaagg
    21241 gagacacggc caatttcttt cagatacata cgaaccgggt cattgatttt tacaccggtt
    21301 ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt tctcagcact cttcaagctg
    21361 tgaattgatg gatcaccatt ttcatccacc acactgatac ctgcgtcttc aatcttttgg
    21421 atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg tagcaagctg attggataaa
    21481 tcatcatata caacttgtcg tttgggtttg ttttctttga tgaaagctgc tactgctgct
    21541 tcatacgttt ttttatctgt tccatttgcc ataaaagaag gccccccttg agtagctatt
    21601 tggcttgttt taactgtttc gttaaattga tgatttcaat cgtcaattca agctcaagct
    21661 gtttgtttcc agttcgtctg gcttcttgct gcatttgttt ttttaatgtt atttcatcag
    21721 ctaagccaga tttgctgatc acatctagca agtcttggat ttctcgtggc gaactttctt
    21781 ctgccaccgg taaatattcg atttccacca ccaaccgcct taaattttca tcttgcaaaa
    21841 agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga gacatatgca tcgaataaaa
    21901 aataaacttc tgcatatgca tcatgaataa actgaaattc tcgttctttt aaaatattac
    21961 ggacagaaac ttctttaaat gcacgatata atagaatctg ctctgccttt tctacttgcg
    22021 tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac ctgagtgtgt tgactttcct
    22081 gaggttcttg acgattttgc tgatttgtcc ttcgaagatc gcgcagttgt ttttgtatcg
    22141 tctctctgcc gatctgaaac tctgttgaca gttgagatag atacatatct tgttcgattg
    22201 gtgaaacaac tcggctaagt tcaactagta attcttcgag gtattcgatc ttgtcttttt
    22261 cattatctaa atttttccct tgttttaaat aacgtgattt aaaagtaaag actgtttcgc
    22321 gcccatgagc cactaattct tggaaagatg cttctccata cttacggaga tattcatcag
    22381 gatcaagctt ttctggaacg actacgacag aaagtgctaa tcgactgttt tgccgaagca
    22441 attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc tccgtcatag caaaagacca
    22501 attctttcgt cagcttttcc atttgttgga tctgttgagc tgttagactt gtccccatag
    22561 aagctaatcc agttttgata ccagcctgcc atgcagcaat cacatccata aacccttcga
    22621 acaacaaaat ttctccgttt ttccggatat cgcttcttgc tttatcaaga ttaaataaaa
    22681 cttgtctttt attgaacagt tctgtttctg gactattcaa gtatttgggc tgatcttttt
    22741 cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc gatcgtctgg ccttgagaat
    22801 tacgaagtgg aaacatcact ctttgataaa aacgatcaga catacggcca tcatcatgcg
    22861 tgacaaacaa tccagagcgt tctaacaatt catttgaaat tgattcattc ttgaatactt
    22921 gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt gaattcttca attaattcta
    22981 aagacaaccc acgactttgc aaatattcta aagctggctg tccagctttt gtatgcaata
    23041 gcatgtgatg atagatttcc gctgcttttt catgagcagc aatcagtttc cccgtagcag
    23101 attcaggatt ttggacagct atagtacgct gacgccattg atcttctaac ggtatctgtt
    23161 cgaagtctgc cacttttacc actgcttctg gaaaacttag accttctagt tcttgaagaa
    23221 aagtaaacac gtttccgcct ttaccacaac caaagcaatg aaaaatctgc ttgtcttctg
    23281 caacagaaaa agacggtgta cgttcttcat gaaaaggaca cagccccaag taatttttac
    23341 cagacttttt caactggaca tattgtccaa tcacctcaac gatattcgtt tgactgcgta
    23401 ctgtttcgat aacctcttga ggaatccgtt gagccatttt ttcaccccct gctctattga
    23461 tatcttttgg gtttaacaga agatatttca ggagaataac cggtaaaaaa tcgcactaac
    23521 tgaaatcagt gcgattttaa aggacacaat tatacatgtt tgattgtatc atatttcatt
    23581 gctttttcaa gtataacaca tttctatctc attaagcatc aatttgctac tcttttcagt
    23641 aactgatttt gaatatcagc cttccagtac aatactcgaa gaacaatatt tacgagcatg
    23701 aatacaaaga agtatcctac gctctctccc aaccctaagt ttacttccaa aattccatgg
    23761 aacagcattg cagctacata tatccctacg atcgtcgtta ctgctaggaa gatgcgcaat
    23821 gggttgaagg gataacaagc ttttacaact gccatgcaac tgatcccaat cagcaagtaa
    23881 tacatcaaag tagtagtttc agcatttccc catgcgaatg tttttccaag tagatacacc
    23941 gcaatgatat tcactactac aagcaaggca tttggtaaag cattaataag tgctgtaggc
    24001 aaataacggt aagtgatttt tcttttatct tgttcaaaag ataaaaagaa ggaaggatac
    24061 ccttcaatcg ctaaatcaat cagcgtgatt tggataggga taaacggaaa tccaattgct
    24121 gtaacggcac atataatcga taaaataaat gaataaatcg ttttgataaa aaagatgcct
    24181 gagactttcg tcacattgtt gaccactcgg cgtccttcaa acaggacttc tggcaatgta
    24241 gtaaaatcag agtccaacaa taccagattc gcaatctgac gtgttgctcc atcaccttct
    24301 gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa catcattcac accgtcgcct
    24361 gtcattgcaa ccgttctgcc gctttctttc aattcattta ccagcaattt cttttgctgc
    24421 ggactcactc gtccaaaaac cgtatagcga tgagcagctt ctcgcacttc catttcttca
    24481 gtaatttgag aaagatcgac atacgcatca taattcggta atcctgcacg tctagcgata
    24541 ttggagacag taaaaggatt gtctccagaa atcactttca gatccacacc ttcctcatga
    24601 agataagcta gtgtttcttg agcgtttttt cggattggat catcgatttc aaacagagca
    24661 accggctcaa caaatgctgg tttttcttcg ttcaattgct gatttggagc gatccccaac
    24721 ataagtacgc gatagccatt cgcttgggct gtttttagac tgtccggaag ccgatcttct
    24781 tccaccaaac gttcaggcgc tcctacgtac acgactccca gttctggaaa ttccatcgcg
    24841 ccccatttgc gatcagaaga aaatgcgact ttgtttgtca catcataccg attagaaagc
    24901 tcaaaataat ctctcatagc ccgcatagtg atgttgttat cactgctttc tgccagatac
    24961 gtccccataa tttctgggat ggctttctcg tacagcggat gtagtgcttc tacccgctgg
    25021 atactcattt tcccttcagt aatggtccct gttttatcca agcataatgt atcgacatgg
    25081 gccagcgttt caattgaata catgtcttga acaaggattc gtttttttgc cagtttggtt
    25141 acccctgtcg ttaatgcaat acttattagc aataccaaac cctttggaag catgcctaac
    25201 aaagctgctg cagatgcaat aacagaaatt ttgatagaag catcgcggat gaacagtgct
    25261 tccaaaaata gtatgatccc caaaggaata atcacgaaac tagtgaattt ggatactttg
    25321 cgaatcgaat ctacaagttc agaacgaata gctttgtgag tctttgcctc gctagtcaag
    25381 cggacagcat aattatctgc acctactcgg ataacttcag ccatgacaga accgcttgtc
    25441 aaaaagcttc cagaaagcaa ttcagctcca gtttctttga caatcaaatc agattcgcct
    25501 gtcaaaagag cttcatttgc ttctgcccgt ccagatataa cctgtaaatc ggctggtatc
    25561 tgttctcctg ctccgatttt taccaaatct cctaatacca gctctttagt agaaatcgat
    25621 tgttctttac cgtcccggat cactagtact tctgattggg aaacaatcga taatttccgt
    25681 acaagatttc ttgcatgtat ttcttgataa attccaataa cgatattgac gacaataatt
    25741 gctaaatacg ccatgttgga atacgcacct acaaataaca gacaaatccc aataccaaag
    25801 ttcagaaaat tgaataacgt caatatatta tcgctgaata tttgttttgt actttttgat
    25861 gcatcttcct ggtagtcatt ttgctggcca gaagccattt tctgaactac ctcttgctgt
    25921 gtaagtccat tcattttctt tttctccatt ttccgccaac tttcaaaaat aatcacgtgt
    25981 ttaagtctag cgtgttccaa gattaaaaac aacttgtttt tataaaattt atagaaaaac
    26041 acacgaatga ttttacaaaa aagatgccaa cctttttgtt tgaatcaccc gtgtgctgtt
    26101 tttattatca atctatcttt acttatattg ttcctccaaa cggctcatcc accaacctag
    26161 tgctgtaccg gctataaaaa gaacaggaca agctagtacc ccagcaactc ccaatcccgc
    26221 gtaatcggta ggaatgatca taatcgttga agcaaaaact acacctaaaa tgaaatggaa
    26281 tagcttgcta tatgcctttg agaaaatgta atccatgatt tttgacaatc caagaacaca
    26341 aagaatccca ccaattccga tcggcacaat cacttcaagt cgtacttctt taaatccgtc
    26401 agccatcgct ttatacaatc ccatatacac caaaaaatta gaagggctca atcctgggac
    26461 gatcataccc aaaccaatca atccgccggc aatcagccat gttccaaaat tctgatcgac
    26521 ttgcccgtca aataattgag cgccgtataa taaaaacaaa taagccagaa caaaagtaac
    26581 aaccatgatg atcacatcag aagtatctct tccttttttc cctgcttctt tccataacgc
    26641 aggaacagtt ccagcgatac atccgacaaa aaaccataat atcgttgttt catacgcacc
    26701 taataaaaaa ctgactaaaa aagaaagtag aaagatgcct gtcactccgc ctagaccaac
    26761 aggcagaaaa aacaaaacat tttctttgaa attttttgta aggtgggcta aaaaagaaat
    26821 cagccgctca tacatgccaa agacagctgc taatgcacca ccgctgactc ctggcaagat
    26881 aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac atccagtctt tggttgtgta
    26941 ccccacttct tgattttcca ttttttgcct tttttccact atttgcgtac tccttctttc
    27001 atttaatttt attcatgatt gaacatttcc tgctatttta cttaaagact ttttcatagg
    27061 tctctattat tttttcattc attttgacaa tatcaggata aaacatgtta cctccattat
    27121 gatagagata gccgccattg taaagcaagg actggatccg ccaatatcgg tattgtttcc
    27181 cttcctcatt tcctaaaagt gggctcagca catctttaga atacgcttct gctaattcta
    27241 ctgtgttttc tccgccatga ttttttacat aggcaatata atctttccca aaattatatg
    27301 cttggacagc tgtccataaa tcgcatcctt gtttctttgc ttctactatc atttccgcca
    27361 aatatttgac accttgatca atactgtcag ctggattatc aatgatctca gcttctccat
    27421 gcagactttc cgagctctgc atgagatctg tcccttttcc ttttgattcg gtcaatatta
    27481 tcgccttgat caaattctcg tagttttcca tatgataatt ttttgcagct gttgttattt
    27541 ctatttgata gctttccact cgttttaccg aacgataagt tcttcctcat aaaaacaaca
    27601 ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat acggataata gataatcgtt
    27661 ttcgcttcat ttcatcacct agttattttg acatcttttt ttatcttact atttctttat
    27721 cttcttggct atttcttcct tgatttctgt gtacgcctta agaaaaaatg aattttcctg
    27781 tattttttga catcttacga aaatgatcgt tgtttttcag taaaaacaat tgcccaatga
    27841 ctgatataat cgttatactt tacacagtag gtgattatgt gaaaaaagaa aagaaatatg
    27901 caaaaatgcc agatgggagc gaaatttact atgaaaagag cggtcaaggc ttccctctct
    27961 ttttactgca tggcaatgac ggcagcggcc gctttttttc agaacaggtc cctgtactcg
    28021 aacgctacta taccgtgtat ctagtagata gccgaggaca tggtcgttcg acaaacgaag
    28081 catctatgtt gaattttcag ttaatggccg aggatctgaa tacgatcatg ttgctggaaa
    28141 aaatcgatca ggcagatttt cttggattta gtgatggagc aaatctagca ctggtatttg
    28201 ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa ttctggaaac acgcttgtta
    28261 aaggcgttcg tttttctgcc agagtcatca gtaatattca ttatgcatgg gtatggttac
    28321 tctctttatt tcgcccaagt cttcgcaaaa atcttttagt tatcaaactt ttgctgcatg
    28381 acatcgggct tacagaaaat gatttaaaaa aaatcaactc ccccactttg atcatcgtgg
    28441 gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat agctaaaact ataccaaaag
    28501 cttcctttgt gcttgtgaaa gaacaaggac atgaattagc tagaaaagat cctgaacgct
    28561 tcaatcgaga agttcttcaa tttctttctg aaacataact attaggaata gaaggtgatt
    28621 tatttgttaa aaaataccat acaatggctg aaaaaccacc taggactgtt caaaacaatc
    28681 tttttgattt ctgtcattgt cattattgtc ggtgaattga tgtccatcgg taaaactcta
    28741 tctatccagc aattaggaga aacgtttgcc actatacctg tatggaaaag cggactaatg
    28801 ctattgattg gtcttatctc tgtgttacct atggttggtt atgatattat tttgaatcgg
    28861 atgcttgaac aaaagcagaa tcctcgttac ctgtttgaga caagctggct gatcaatacg
    28921 atcaacaata ttgccggttt cggcgggttt gttagtgtgg ggcttcgctc tgaactatat
    28981 ggacaaaaga aagagagcag aaacgtgatc caagcattat cgaaagtttt cttgtttttg
    29041 atggctggac tttctattta cagtctgctt tcttttttac ttgtagtctt cacgccagtt
    29101 gctccttttt tgaagcaata ttggatatgg ttgatcggcg gcggtctata ttttcctgtc
    29161 gtctttttat ttactacttt caaaaagaaa ggattccttg gtggtacctc acttaaaact
    29221 caaggacagc tattgctagt ttcattgttg gaatggaccg gtgtcctgtt tagtttcctt
    29281 tctgttggtt atttaatgga aatccggatt gatctgtggc aaacaattcc attattcatt
    29341 gctgcttcag tgataggaat cgtgtctatg attccaggag aaattgggag tttcgatgta
    29401 atgatgatta tcgggttgtc cgctattggt gtgccaagag aaatagtcgt tgtgtggatc
    29461 ttgctctatc gcctgttcta ctacatcatt ccgtttttga ttggaatcgt ctttttcttc
    29521 aaaaatatcg gttccacttt tgatcagcgt tattctggta tccctaaaca attagcaaca
    29581 gaaattgcgc ataaaatcgt ggttgtctta ttatactttt ctggaatcat gctagtactt
    29641 tctgccacta tcccgcaagc ttttacagag tttcgctggc ttcatagttt gaacccattg
    29701 aaatttcatt ttattatcca atttcctagt atactattgg gatttctttt aatcattatg
    29761 ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc ctacaatctt cttgattgtt
    29821 ctagctttac tttatgtttt attaagtgat tttagtttca caccggtggt tttcttgtct
    29881 attctgcttc tgatcattct tgcttctaaa aacgaattat ttcgggaaca attgatctat
    29941 tcatgggagt ggcgtacgat cgatggaatc attattggtg cactgtcctt gctttacatc
    30001 gttattgggg tatacaatct gccggatttc cctcatcggc gtcaccattt tatttccttt
    30061 ttcttatttc cttctgaaaa gatttggttt tcgggattgt tggccatcat cgctgttagt
    30121 ttcatgatcg ttctatttgt tcatttcctt caaggagaaa agaaacagat tggcgaagcc
    30181 tttaatgaag aaaaggccct gaagatcctt acaacttatg gaggaaactc cgatagtcaa
    30241 ttgatcttct taaaagataa gcggatgttt gcctatgaaa aagacggtga accaactgtt
    30301 cttctccaat tcgcttgctt caataataaa tgtattgtaa tgggtgatcc ttctggtaag
    30361 aaagaagatt ttccagaagc aatcgaagct tttatcgaag aaacagatcg actatgctat
    30421 ttaccagttt tctacgaaac aagcgaagag attgttatga ttttgcatga attcggctac
    30481 gatttcatta agatggggga agaagcttat gtagacctga atagttttac aacttcaggg
    30541 aaaaaaatga agggcactcg tgctgtcttg aatcggatcg aacgagaagg atttacattt
    30601 gatgtcttac aaccaccatt ttctactgag caaatgagta ctttcaaaaa tatctctgat
    30661 aattggttgg gttcacgaaa ggaaaaaggg ttttctttag gctttttctc tgaagattat
    30721 ctacaaagag cgcctattgc agttgtcaaa aatacccaag aagaaattgt cgcttttgca
    30781 acgatcatgc ctacttacac gaacaataaa gtaggaacga ttgatctgat gcgatatgat
    30841 tctaaaaaag caccttctgg cagtatggat ttcttgttct tgcatttgtt tgcctatatg
    30901 aaagaagaac atatccaatg gttcaattta gggatggccc ctctttcaaa tgtcggaact
    30961 tccagaaaga gttttttaca ggaaaggatt gcatacttgg tttacgagtt tggttctcat
    31021 ttttattctt tccatggatt aagagaatat aaaagcaagt acgctacaaa ctgggtctca
    31081 cgttatactc tatattctag agatagttgg attgcatatg ttatgattgc tttgctgatt
    31141 attgataatg cgccagttga gcagacacaa ggtagaataa gtggtttgaa aaaatggata
    31201 cgaagaaagt attaaaaact gcataccgat agatgaacac tctcatgatg aataaaagag
    31261 actgaagtaa aacgaaagtt catgcttcta caatctcttc ttatacaatt gaagaacaaa
    31321 gagcggtcca aacagaaatc ctgtttggac cgctctttta ttttaaacat ttttcattac
    31381 caaaatattc gagtcgcgtt tcttatgctt cgatctctgt aacgatacct gaacctactg
    31441 tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc aacagcgatt ggatggatca
    31501 agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat ttctgtatct tctggcaatg
    31561 tgattgttcc tgtaacatca gttgtgcgga agtagaactg tggacgatag ttgttgaaga
    31621 atggagtatg acgtccacct tcttcttttg tcaacacgta cacttctgct ttgaattttg
    31681 tatgtggagt aatggaacct ggtttagcaa gtacttgtcc acgttcgata tcgtcacgtt
    31741 ggatcccccg taacaacacg cctacgttat ccccagcttc cccgtaatct aacgttttac
    31801 ggaacatttc tacacctgtt acaactgctt tttgtgtttc aggtttgatc cctacgatct
    31861 ctacctcatc accgacacga acagcaccac gatcaatacg acctgaggca acagttcctc
    31921 gacctgtaat tgagaagacg tcttccactg gcaatagtaa tggtttatct gtatcacgtt
    31981 ctggtgttgg gatatattca tctactgtat ccatcaattc cataatagca gcttcagcat
    32041 ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat cacaggagtg tcatcgcctg
    32101 ggaaaccata ttcgctcaat aactcgcgaa cttccatttc taccaaatcg atcaattctt
    32161 catcatcgac taaatcaact ttgttcaaga aaacaatcag gtattttaca ccaacttggc
    32221 gtgacaataa aatgtgttca cgtgtttgag gcatcggacc gtcagttgca gaaacaacta
    32281 agattgcacc atccatttgt gctgcccctg taatcatgtt tttcacatag tccgcgtgtc
    32341 ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc atattctacg tgtgcggtat
    32401 tgatcgtaat cccacgttca cgttcttctg gagctgcatc aatactagca tagtcttgag
    32461 gatttgctag gccttttttg cctaatactg tagtgatcgc agcagttaaa gtagttttcc
    32521 catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg tttacttctg tcataatgtt
    32581 cttttgccat aatttacaaa cctcctaaat aatatagatc actgaaaaat ttcagctctc
    32641 acctttttat tatagtcttt ttttgactaa atcaaaaaga atacgtccga cttacttttt
    32701 gtaagattcg aactaagctt attatacgtc aatattggtc aaagtcaact aagagcactc
    32761 gtctgtctta tacgcgaaaa aagtaccttt tataaataaa aaaatgtgtt ttttgagaaa
    32821 aacttcaaga tagtccttaa ctttcttttg aagcaataag aacaaaatga ggaaaagttt
    32881 aaaattcagc tgttgccaac aactttcaat agacgaaatc ttctatttcg ttaataataa
    32941 ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact tgtcgtttta ggcatatttc
    33001 tcggcggaag ttttgcagct tatcattatt tttacggcgg cgaagcttat tatacaaaaa
    33061 tcacgacgaa tggcgaaatg tcagctaccc aagcagataa cggagagaaa ttcacgactt
    33121 atacctacaa gcaagcggct tataataaag atggtgaaaa aaaacaggtg acgcttcgcg
    33181 aagaaagaga acatccatta aagatgaatg cgtatcttaa actcaaagtc aatcctcgta
    33241 aaggtgtatt aagctgggaa gaaataaagg cttctgaagt gcctaaaaat gcggcagaaa
    33301 aaatcgataa ttagtaaatg gtcttaaaat tttattagat aaaaagaggc tgggacagaa
    33361 gcgtttaact ccaagaaata agaaggagtt gcttctgctt ccgccgttta tacgtgttta
    33421 gagcgtgaga caaaagtgtt ctttactttt gtctcacgct ctttttttgt tatattcgtc
    33481 ttttccgatc cttctcttga cacaattcat ttaactgatc actggtactt gaacacctaa
    33541 tattctagtc atttttataa acgattcaat acttcatcca catttttgat catcacggat
    33601 atcgtaccat ccggattatt cacaaattca atcaaatctg ggttgcgata tacatctact
    33661 ggtacgatca gttcgatccc gtttgatagc ttgaattttt gttttccaaa ttttttctca
    33721 gaaatttctt gtacttcttt tacaggaggt gcttctggga caaatccttg ctcttgtact
    33781 tcttctttaa aagccatttt tgccgtgatg ttttccttga agactttttc cgcaatcatc
    33841 tcatgatcca accgaccttt ttcttctatc gtatcataga cagcttcttt caaatcagcc
    33901 atgatatcaa attcttctgt ctcaaatttt tttccaagat gcttggctac tttttggatc
    33961 acttttacat tttcttctaa agaaggtgca ggaacacttt cgatcactct tccagaaaaa
    34021 taaagctctt ttttgccaga aaactcatat tttttttcaa ttaattcgta ggtccaatca
    34081 gtcaaattca cagcgaatgc ttcatctgct ttttgtgttt tcgcccctag aattgctcga
    34141 ttcaaaatca agcggttgtc gatccctgct tcgtctgctt caacaaagtg agtgtaagcc
    34201 tcacgataat tgactttcaa taaagataag tacatcactg tatctaattc atacaagaca
    34261 acaaatacat ctgcactagg tgcttcttca ctttcttggt agatatcgaa ccaccgctga
    34321 acgattgctt cacttgcttc cacaaaattt tcttgagcga ttttaagtga ttcaacgatc
    34381 atgctttctt ctgctagttg tccagttttt gtttgagcag aagagatttt ttggatcttc
    34441 ttttgaagaa aatcacgaat atattctttt gtcagatcca gctctttttg tgaaaagact
    34501 ggagaaccag tttctctgtc aataatatgc agaattgctt tttttaaata gatatccatt
    34561 ttctcattcc cttctgtctt agtttacgga aaaaaaatca aaaataccag aatcaaaatc
    34621 attttctttt aaacaaaaat ttcaagagta gaaacaaaat ggattctttt tttcgaaaaa
    34681 tgcgctacac ttatagttga acgaataaaa aaggagctga aagtatgaat tcattaacaa
    34741 gcacttatcg tctatcaaat ggttacgaaa tcccggtagt aggattcggc acatggcaaa
    34801 cacctgatgg ggatgtcgct gtttcctctg ttaaagaagc gctggctgca ggttatcgcc
    34861 atatcgatac tgcccaagga tacaagaatg aagaaagcgt cggccaagcg attaaggaaa
    34921 gtggaattcc tagagaagag atattcttga caacaaaatt atggaatgca aaccacagct
    34981 atgaacttgt gatgtcttct tttgaagaat cattgaagaa gctccaaaca gattatttag
    35041 atctgttttt gatccactgg ccaaaccctg ttgcttttcg tgataattgg gaacaagcaa
    35101 atgcagatac atggcgagca tttgaagaac tgtatgaagc aggtaaaatc aaagcaatcg
    35161 gtgtgagcaa tttcttaccc caccatctag atacactagc aaaaacagca aaaattatgc
    35221 cgatggtcaa tcaagttttc cttgcaccag gcgaattaca gacaactgta gttgagtatg
    35281 caaaaaaaca tgatatgatc ctcgaagcat atagtccatt aggcactggt aaaatcttcg
    35341 atgtgcctga aatgaaacaa atcgctgaag cacatgacaa gacgattgca caagttgctt
    35401 tgcgttggtc gctgcaacac gaattccttc ctcttcctaa gtcagtgaca ccaagcagaa
    35461 tcaaagaaaa tactgaatta tttgattttg aattaacaga agaagaaatg aaacaaatcg
    35521 atcagttaga tggtgtagtc ggcaaagcaa aagacccaga tactacccaa ttttaagtcg
    35581 aaaggtgatt ttatggatcc aatcgaacgc ttgaattctc tctcggaaga agttacccag
    35641 acttttcatt ccgattttgt ctttttgatc gatgcagaga aaatccaaca ttttcctgca
    35701 agaaactgga cacatgatca aatcatcgaa gaactgaaaa aacggttcga tcattcgcta
    35761 atggtcaaac cctggcacga acatgaagtc atttattcac ctgaactacc tgtttttgcc
    35821 ttgataccga aaaaatagaa agaatggaac ggattatgta tatatacata atccgttcca
    35881 ttttttattt ttctttcaaa aaacgggaaa atacgcaaat ttttctgttg taatttgcgt
    35941 atacgcaagt ttttttgcat tactcctttt catttggctg tttttttctt ataatcgaaa
    36001 gggtatgagc gaaggagaga acatatgaag aaaaaacaga aacaaaaatt attaaatcaa
    36061 ttccgtcctt cattggatgg tgtaagagga caattattcc gttctctaga agaagagagc
    36121 ttgcgacgtt atggtttgcc gttacaagtc atgcttgatc ccaaaaaccg tcaaatctta
    36181 acgatcggat tagctgggaa aacaaatgaa gatacacgga tcaacgtgcc aatcgatgac
    36241 aacttcaata ctgtattaaa gagaattcgt tcaggagaaa acgggatttt cgaacgattc
    36301 cgtgacaatc ttcttattga aatcgtgtct tactggaatg atcaacgatt gaaaaacgat
    36361 gaaccaactg cgcaagctgt tgcgacacca gttacagaag aaacagtcag tgtgccagaa
    36421 gaaaaaacgg aaaaaccaaa agcggacaca actgaaaata cacgctcaac tgatacgaat
    36481 gccgctttaa gttttgctga tttttcaaaa gccgttgctg agtatcctaa attttacaca
    36541 gaacaaaatg aacatgaagt agttattaat gaaaaaaatg ctgatgaacc tcgtaaatta
    36601 gcaactattt ctatgactac tgaaaatgag ttcgttatcg aaaaagcact cgaacggaaa
    36661 tacaaagtca aattgacttt gattcctttg atcgaacaat ttgcagcgac agcgattact
    36721 gatcgataaa aattctattt gtcataaaag gctgggattt aaaatcccag cctttttagt
    36781 catataataa tttctacagc aagtaaaaag aaattccttc taacatcagg ctcaaatatc
    36841 agcttgacct gtccaacaaa tcacctatga tcctacaatg ttaggcgact tctcttctac
    36901 ctgaagatat cttggagttg cctgatttct taagatgcct aaccttaact ataaaaaatt
    36961 ctaataataa acatattttc tgatagagaa aaaagcggtt ctataatatt ttgtgttggt
    37021 ggaaaatcga aagcgatttt ctactaacac ttttttcttc gtttcaactc aaaaagagac
    37081 tcacttttgg taaaatttag tcgaccaaaa cgtcacccta ccaaaggagt ctctc
//
LOCUS       DACCVH010000018        37082 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.018, whole genome shotgun sequence.
ACCESSION   DACCVH010000018 DACCVH010000000
VERSION     DACCVH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.018"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            112..1077
                     /locus_tag="IVV98_000980"
     CDS             112..1077
                     /locus_tag="IVV98_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP7806654.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1134..1364)
                     /locus_tag="IVV98_000981"
     CDS             complement(1134..1364)
                     /locus_tag="IVV98_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP7806655.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1450..2337)
                     /locus_tag="IVV98_000982"
     CDS             complement(1450..2337)
                     /locus_tag="IVV98_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP7806656.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2426..3649)
                     /locus_tag="IVV98_000983"
     CDS             complement(2426..3649)
                     /locus_tag="IVV98_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7806657.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3666..4745)
                     /locus_tag="IVV98_000984"
     CDS             complement(3666..4745)
                     /locus_tag="IVV98_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7806658.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(4876..6603)
                     /gene="ptsP"
                     /locus_tag="IVV98_000985"
     CDS             complement(4876..6603)
                     /gene="ptsP"
                     /locus_tag="IVV98_000985"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP7806659.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6603..6869)
                     /locus_tag="IVV98_000986"
     CDS             complement(6603..6869)
                     /locus_tag="IVV98_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP7806660.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7348..9582
                     /locus_tag="IVV98_000987"
     CDS             7348..9582
                     /locus_tag="IVV98_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP7806661.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9730..10050
                     /locus_tag="IVV98_000988"
     CDS             9730..10050
                     /locus_tag="IVV98_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP7806662.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10255..10479)
                     /locus_tag="IVV98_000989"
     CDS             complement(10255..10479)
                     /locus_tag="IVV98_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAP7806663.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10677..12257)
                     /locus_tag="IVV98_000990"
     CDS             complement(10677..12257)
                     /locus_tag="IVV98_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP7806664.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12658..14034)
                     /locus_tag="IVV98_000991"
     CDS             complement(12658..14034)
                     /locus_tag="IVV98_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP7806665.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14162..15280)
                     /locus_tag="IVV98_000992"
     CDS             complement(14162..15280)
                     /locus_tag="IVV98_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7806666.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15422..15856
                     /locus_tag="IVV98_000993"
     CDS             15422..15856
                     /locus_tag="IVV98_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806667.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15934..16467)
                     /locus_tag="IVV98_000994"
     CDS             complement(15934..16467)
                     /locus_tag="IVV98_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP7806668.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16561..17739)
                     /gene="mutY"
                     /locus_tag="IVV98_000995"
     CDS             complement(16561..17739)
                     /gene="mutY"
                     /locus_tag="IVV98_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP7806669.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17732..18529)
                     /gene="recX"
                     /locus_tag="IVV98_000996"
     CDS             complement(17732..18529)
                     /gene="recX"
                     /locus_tag="IVV98_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP7806670.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18636..20018
                     /gene="rlmD"
                     /locus_tag="IVV98_000997"
     CDS             18636..20018
                     /gene="rlmD"
                     /locus_tag="IVV98_000997"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP7806671.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20192..20770)
                     /locus_tag="IVV98_000998"
     CDS             complement(20192..20770)
                     /locus_tag="IVV98_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP7806672.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            21092..21562
                     /locus_tag="IVV98_000999"
     CDS             21092..21562
                     /locus_tag="IVV98_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP7806673.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(21670..22896)
                     /locus_tag="IVV98_001000"
     CDS             complement(21670..22896)
                     /locus_tag="IVV98_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP7806674.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(23650..23850)
                     /locus_tag="IVV98_001001"
     CDS             complement(23650..23850)
                     /locus_tag="IVV98_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7806675.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(23984..24592)
                     /locus_tag="IVV98_001002"
     CDS             complement(23984..24592)
                     /locus_tag="IVV98_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP7806676.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(24677..25147)
                     /locus_tag="IVV98_001003"
     CDS             complement(24677..25147)
                     /locus_tag="IVV98_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP7806677.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(25195..26109)
                     /locus_tag="IVV98_001004"
     CDS             complement(25195..26109)
                     /locus_tag="IVV98_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP7806678.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            26255..27058
                     /locus_tag="IVV98_001005"
     CDS             26255..27058
                     /locus_tag="IVV98_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP7806679.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            27236..28183
                     /locus_tag="IVV98_001006"
     CDS             27236..28183
                     /locus_tag="IVV98_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP7806680.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(28251..28544)
                     /locus_tag="IVV98_001007"
     CDS             complement(28251..28544)
                     /locus_tag="IVV98_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP7806681.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(28572..29237)
                     /locus_tag="IVV98_001008"
     CDS             complement(28572..29237)
                     /locus_tag="IVV98_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP7806682.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(29377..30009)
                     /locus_tag="IVV98_001009"
     CDS             complement(29377..30009)
                     /locus_tag="IVV98_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806683.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(30016..31083)
                     /locus_tag="IVV98_001010"
     CDS             complement(30016..31083)
                     /locus_tag="IVV98_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7806684.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(31080..31811)
                     /locus_tag="IVV98_001011"
     CDS             complement(31080..31811)
                     /locus_tag="IVV98_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP7806685.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(31980..32459)
                     /gene="greA"
                     /locus_tag="IVV98_001012"
     CDS             complement(31980..32459)
                     /gene="greA"
                     /locus_tag="IVV98_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP7806686.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(32595..33770)
                     /gene="mltG"
                     /locus_tag="IVV98_001013"
     CDS             complement(32595..33770)
                     /gene="mltG"
                     /locus_tag="IVV98_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP7806687.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            33974..35143
                     /locus_tag="IVV98_001014"
     CDS             33974..35143
                     /locus_tag="IVV98_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP7806688.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(35410..37032)
                     /locus_tag="IVV98_001015"
     CDS             complement(35410..37032)
                     /locus_tag="IVV98_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806689.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        11312 a         7363 c         6073 g        12334 t
ORIGIN      
        1 ttttgattat caaagtattt tctgtgaaca gaactataga attccctaaa acttgtccat
       61 tatttcaaaa tttgttatag tctttttatt caaagcgtaa aaggagatcc tatgttaaaa
      121 gaaaaaatga aaactctccc catgctgccg ggtgtctatc ttatgaaaga ccgagatggt
      181 aaggtcatct atgttggtaa agcaaaacgg ctcaaaaata gagtaagcag ctattttcat
      241 cagaataaac agcattcaaa aaaagtatta cgtatgattc atcatataac agattttgat
      301 ttcgtcgtag tagacacgga attagatgct ttattgctcg agtgtcaatt gatccaacat
      361 taccgtcctt tttataaccg acaaatgaat tatttcagta attataatta tgtacatatt
      421 accaataagg gatttgtatt aacagatact cctacggctc gaacatacgg gccttttcgt
      481 ctctataaaa aaatgccgtc tattttgcgt ataatggaag aaacttatca aatgccttgg
      541 ttgtctgaaa ttagtttgtt agctttgcga gtccagcttc ctgacctaca ggaaatgact
      601 tttgaacaga aaaaaaagga actccaaggg ctgtttcaag gccgaaataa aaagctactg
      661 acttacttga aaaaaagaca acaacatttc atctatcagt tgaatttcga aaaagccggt
      721 atgcttcaaa aagatatcga attagttact tattttatta gacggatcca ggaacaaaag
      781 cagtttttaa gaacaccatc gctcaccttc agcatgccat tagcagcaga tgagagtcag
      841 aaaaagcact acctcgtttg ttatggtcaa cttgcagaaa caatgattac ctctggtgac
      901 gtttctcctg acttctatta tgaaaagaaa gaagctcatt tatctttgaa acgtcaattg
      961 tcaaaagaag aaatcgatcc tgtacaaatc ttgatcagtt accgcaaaaa attagaaaaa
     1021 gaacagtttg aaattgaact gttaaacaaa aaagaagctg aaaagcaact aaattagttg
     1081 cttctcggct tcttttaggc atcttcaact tcaaatgtca attatcctaa aatttattgg
     1141 attaagtcat agatttccat cgctacgata tcgatattat caaattcgta ttgctgatga
     1201 gtatctgttt cagttaattc aaatgtatcg gtcgctttat cataagttac tgtacacttc
     1261 tctacgcctt ctttttcaaa acggcgaact tgcagttcat tatctgctga ctcgaccata
     1321 gcctccagtc gttttatgat tgcgactaat tgtgaatgtg tcatcggagg tcctcctttt
     1381 cttatttctg ttatattgta tcaaaagcat agcctacttg cattgatttt ctctaaaaaa
     1441 actcgttttt tatgattttt tttctggtat ttttccttca ggccaccaaa gtttgatcaa
     1501 agcttgggtt ccgtcattct caaaaccttt atctgccaac tcttcatata gtttcaatgc
     1561 ttgggtagtt gctggcaata caagatccat tttttctgct tcttctaatg caatctttaa
     1621 atctttgata aaatgtttga caaaaaaacc aggtgtgtaa tcttctttta aaatacgagg
     1681 agaataattg cttaaagacc agttagctgc acttccacct gaaagcgtct caatcacttt
     1741 ctttaaatca agtccgtttt tttgtgcata gacaagcatt tccgtcattc ctgtcatcgt
     1801 acctgcaatc atgatctgat tagccatttt tgtatgctga cctttcccag cagaaccatg
     1861 caatgtaaat gtcgtaccaa attctttgaa taaaggcagt acttgatcat aaacggcttc
     1921 ttctccaccg accatgatcg tcagtgtacc attctttgct cctaagtcac caccggatac
     1981 cggtgcatct aacgcatctg cgcctttttc ttttgctgtt tttgcaattt tttctgccag
     2041 gcttggtgta cttgtagtca aatcaactaa aatatgtcct gagatatctg cagaaaaaat
     2101 ccccgactgt ccatagtaga tttcttctac atctttgggg taacctacca ttgtaaagag
     2161 aatattactt tgttctgcta ccgcttttgg tgtatctgcc cagatagctc cttctgttac
     2221 taaaggatca gcttttgctt ttgtccgatt atagacagct acttcgtgtc ctgcttctag
     2281 tagatggcgt gcgacagcac ttcccatgac gcctgttccg ataaaaccaa gtttcatttt
     2341 ttcgacctcc taaaaatcaa aaatccttgc ttctatgcta gtatacgcta gaaacaagga
     2401 ttttttcata aaaaatgttt gaattttatc ttttaaatga atttaatttt attttgattc
     2461 gttcaatcga gtcttcttct tcttttcttc gcatctcttc ttcatgataa acaaccatgt
     2521 cttgataaaa ttcgatcata gcttcgccga aatgtgtaga tgaaatatca taaagtttag
     2581 cttctaaaac ttttggatct ttaggaactt cactggaaat ataatcaata agtgctggtg
     2641 caaagtcttc gtcggtttca aaagttttcc ctaatgaagg atgatcgaac aatcggttca
     2701 aataagcatt tccttccacg acacaaggtg ttccggctgc catcgcttct gtataagtaa
     2761 gcccttgtgt ttctgaagta gaagcactga caaaataatc tgccgcttta taataaagtg
     2821 ctacatcatt gttgtccact tctcctgtga actgcacaaa ttcttctaac tgcagttctg
     2881 agatcaattc ctctaactct tctacataag gtccttttcc tacgataact aatctggcgt
     2941 taggataagc ggagatgacc tgaggaaacc cattaatcaa ggcttggata tttttctcat
     3001 aagaaatcct gcttaaagaa agaatcatca aatggttttc ctgaagacct agtgactccc
     3061 ttaatttgct gatatcctgc tgagtgatat cagaacgttt gaatttttca atgtcgatac
     3121 cagtaggaat cacgcgaagc ggtgctatta caccatagct gcgtaatgta tcaataacac
     3181 gttcacttgg acaaactaca cctgtcgtat gatttgcaaa taatctagac aagtatttta
     3241 catgggattg cctgatcact tttcctttac cgatataatg aaggtagtct tcatacatcg
     3301 tatggtaagt atggatcaga ggtattttca acttcttagc taccatcttc ccaagtatcc
     3361 ctgctccgaa ttctgtatgg gtatgaataa gatctagttc tagttctttg gcaaccaaat
     3421 aagcatacca catgcctcta acaacaactc ttcgatcctt gaaagaaata aatggtacac
     3481 ttggcattcg aatcacatct ttttccaact tatccgcatt aggatcggtc gttgtaaaaa
     3541 tatagacttc atgcccatgt ctttctaatt cttgttttaa tgttttgatc gatgtagcaa
     3601 ctccgctgac ttgcggaaag taggtatcgg taaaaaagcc gattttcatg tttttcgcct
     3661 ccaaactagt ccttgacctg atttactttt tttaatttgc tagagacttt ttcattcagt
     3721 acactttcgt atacattttt aagttcttca ccgattttat tgatacttcg ctcttttgct
     3781 gtttgataac cggcttgtgt cgtactcggt agttcttgat tggtaatctg ttggatcagt
     3841 cggataaatt cttcgtttgt cttccccata tagcagttct tgctatcttc taaccagcca
     3901 ttatacactg gaatatctcg aacaagtacg ttttgtttgc ttgctaaagc ttctaaaaca
     3961 acgatccctt ctgtctcttc ataagaaggg aaaaagaata gatctgcacc tgaatacgca
     4021 ccttctatga tctctccacg aatgtaacca ggaaacagga cattttcagg atgatcttct
     4081 tttacaattt tccggatgtt ccgaggaatc gagtacatgg gaacatgacc aaaccaaata
     4141 aatgtgtatt cgggcatctt cttagcaatt tctacgaaat caatgattcc tttacgttcg
     4201 aaaaacaaac cgacacaaat gattactttt tgatccggag acagtttgaa atattctctg
     4261 aacttttgtt ctttcattgg atcagggtga tatttctcta agtcgatccc attggaaata
     4321 gcttgaatcg gcacacggat accatagctt tccaacaact gttttgaata aggtgttggc
     4381 gtgatcagat agtccgcttt ttggtacaat cctaccagat atttttttac gataggagaa
     4441 agctggttcg atctgataaa ggaatttcgg aaatcttcct ctgtagaatg cgcatgatag
     4501 acaacttttt ttccttctct tctggcttta ttgaccatat tatgactatt gattccgtat
     4561 gtattgatgt gcaggatgtc ataatcttct ttttcatcta gtgtataaga gataccgact
     4621 tccgtcagag cacgtttttg atgatcaagc gcacgcccga ttccagattt tgcaagcatc
     4681 ttttcacttt caaaatataa taataccttc accttacgtc ccccttcact tatatagtat
     4741 aacatagcct acaaactgtc actcaaactt aagccctatt tttgtctatt cttactgaca
     4801 aaaacgtttt cttaaaaaag aacaaaaaaa ctggcgtagc tcttttacaa gccacaccag
     4861 cttttgatac gttgtttatt ttacatattc atgaacaagt tcaacgactt cttccatcat
     4921 atcgcattct ttcaatgcac gatcagcaag ttcagccatt ttcgctgtgt ccaagcgttt
     4981 cattaaacta cgcgttttaa gaatagatgt cgcactcatt gagaactcat ctagacccat
     5041 acctactagc aatggaacag ctgtttgatc tccagccatt tctccacaca tacctgccca
     5101 ttttccttca gcgtgtgctg catcaattac atttttgatc aaacgtaaaa ttgatgggtt
     5161 atatggttgg tacaagtaag aaacgcgttc gttcatacgg tctgctgcca ttgtgtattg
     5221 aatcaaatcg ttcgtaccta cagagaagaa atctacttct tttgcaaact tgtctgctaa
     5281 gactgctgct gctggaatct cgatcatgat gccgacttgg atcgtatcag atacttcctt
     5341 gccttcactt atcaattttt gtttttcttc ttcaaagatc gcttttgctg cgcggaattc
     5401 tttgagtgta gctaccatag ggaacatgat acgtaaatta ccatgaacag atgcacgaag
     5461 caatgcacgc atttgtgtac ggaacatttc gtcgccttgt tcagataaac tgatacgcaa
     5521 tgcacgatat cctaagaatg gattcatttc atgaggtaat tgcagatatg gtagttcttt
     5581 atctccaccg atgtccattg tacgaacaac tacaggtttt ccttccatac cttctaatac
     5641 agctttgtaa gcttcatatt ggtcatcttc tgttgggaag tctggagaat ccatatacag
     5701 gaattcagta cggtacagac caactgcttc tccaccatta ttatggacac caactagatc
     5761 ttttggtgtt ccgatgtttg cagctaattc aaaatgcttg ccgtcagctg tgacagtttc
     5821 tgcatttttt aatttttccc attctgcttt ttgtgctgcg taatctgcac ctgctttttc
     5881 aaattcagct ttttgttcat ctgtaggatc gatgattaca tcgccttcga tcccgttgac
     5941 agccaaaata tcgccttctt tgactttagc agtaatttct tttgtcccaa cgattgctgg
     6001 aatttctaaa gaacgtgcca tgatagcaga atgtgaagta cgtccaccaa tgtctgttac
     6061 aaacgctttt acaaaattgc gatctaattg tgctgtatca cttggagtca agtcatgtgc
     6121 aacaacgacc acttcttcgt tgatcattga tggatttggt aaagtaacgc ctaataagtg
     6181 cgctaaaata cgtttagcaa cgtcacgaat atctgcagca cgctcttgca tataagcatt
     6241 atcttccatt gcttcgaaca taccgatata catatccgtt acttctttta gcgctgattc
     6301 agcatttacg ctgttgtctt taatattttg cttgatttga cctaccattt ctggatctga
     6361 aagaaccatc aaatgggcat caaatacttg cgcttctgct tcacctaagc tttgcgctgc
     6421 tttttcacga atttgctgca attcttcagt agatttagct aatgcagcat ccaaacgagc
     6481 ttcttcagcc gcagtatctt ctactgttgc cttactgaat gttaaatccg gttgaactag
     6541 caggtaagct tttgcaacgg ctacaccgtc actagcggca atccctttta gcatttcaac
     6601 cattattcag ataagccttc tttcttcatt gtttcaacga ttgctgccat tgcatcagct
     6661 tcgtcagcac cttctgcagt aatagtaaca tcagaacctt gacctacacc taaagacata
     6721 acgcccatga ttgatttcaa gtttactgat ttacctttat actctaagtt tacatcagag
     6781 ttaaatttgc ttgctgtttg tactaatagt gtagctggac gagcgtggat cccagtttct
     6841 gctactacgt gaaattcttt cttttccata ttaatcggtc tcctttaagt gagtgttgtt
     6901 tttatgtgag ggttttcttt tttagtaatt cagagaatcc taacaaatgc caccctttca
     6961 tctgtaaaga ttaacatttt ttttcgttag atacaacagt tttcattcaa tttcagataa
     7021 aagtattcaa attattccgg attctttttc atccttttct tcacatttta taacaaacgt
     7081 gtttatttcc tttttcttgt cgctttctct tctcctgacg tttatcattc tttcctttga
     7141 ccctctttgt tttcatatga aacgaattac ttgcttccct ttttattttt agtataataa
     7201 gagtcaaagg tcaggaatgg tcaatagaga tttcaccttt tctacctcat aaatctctta
     7261 aaaaactagg ggttattctt ttacctcatg aaaaacgaga tgtaaaatat ggatgtaccc
     7321 atttttgtga aaggacgtga atgattcatg ctttgtcaaa actgcggcaa gaatgaggca
     7381 acgattcact tgtatgccac tgtcaatggt cagcggacac aactcgatta ctgtcagagc
     7441 tgttatcaaa aaatcaaaaa tcaacaaaat ggaggtctga ctaatatggc ccaaaatgat
     7501 ccatttggat ttggcagttt ggacgatctt ttccgttcca tgtctcgcca aatgcaacag
     7561 caaggaaatt atgagcaaac accaccaaca caatttggcg gaaacaacaa cttcaatggt
     7621 ggtcagccac ctcaaggcaa tacagaaggt ttattgggag aatacggaat caatatcaca
     7681 gaacaagcac gacaaggtga tatcgatcct gtgatcggac gcgatgacga aatcaaacga
     7741 gtcattgaaa ttttaaatcg ccgaaccaag aacaatcctg tcttgattgg agaaccaggt
     7801 gttggtaaaa cagcagttgt tgaaggttta gcacaaaaaa tcgtagatgg tgatgtaccg
     7861 caaaaattaa tggacaaaga agtcattcgt ttagatgtcg tatctttagt ccaaggtact
     7921 ggtatacgag gacaatttga agaacgtatg caaaaattga ttgaagagat ccgtcaagca
     7981 gaaaatgtga tcctattcat agatgaagtt cacgaaatcg tcggtgctgg ttctgctggt
     8041 gatggaaata tggatgctgg taatatttta aaaccagctt tagctcgagg agaattgcaa
     8101 atggttggtg ctactacctt aaatgagtac cgcatcatcg aaaaagacgc tgctttagaa
     8161 cgtcgtatgc aacctgtacg ggtagatgaa ccaactgtcg aagaaacgat cagtattttg
     8221 aaaggtttgc aaaaacgtta tgaagactat catcatgtaa aatatactga tgaggccatc
     8281 gaagcagccg caactttatc caatcgttac gtccaagatc gcttcttgcc ggataaagcc
     8341 atcgatttgc tagatgaaac aggttctaag aaaaacttga cgatccaaat cgttgatcct
     8401 aaaacaatcg agaaaaaact gcaagaagca gaagaacaaa aagttttagc ttctcgagaa
     8461 gaagatttcg aaaaagcagc ttattatcgc gatcagatca ataaacttca aaaaatgaaa
     8521 gaacgtcagc tcactgaaga ggaaacacct gtgattaccg aaaaagatat ggaaaaaatc
     8581 gttgaacaac ggacaggtat tccagtgggt gaattaaaag aaaaagaaca gacacaactg
     8641 aaaaacttag cagatgactt gaaagctcat gtcatcggac aagataacgc tgtagatcga
     8701 gtagcgaaag cgattcgccg aaaccgtgtt ggattaaaca aacagaatcg tccaatcggc
     8761 tccttcttat ttgttggacc aactggtgta ggtaaaacag agcttgcgaa acaacttgcc
     8821 tacgaactat tcggttcaca agattcaatg attcgtttcg atatgtctga atatatggaa
     8881 aaacatagtg tctctaaatt gattggttct cctccaggtt atgtcggata cgaagaagct
     8941 ggtcaattaa cagaaaaagt acggagaaat ccttacagtc ttgtcttgtt agatgaagta
     9001 gaaaaagctc atccagatgt tttgcatatg ttcttgcaaa tcttagatga tggtcgattg
     9061 acagatgcac aaggaagaac ggtcagcttt aaagatacga tcatcattat gacaagtaat
     9121 gccggaactg gtaaagtaga agcaaacgtt ggttttggtg cggcacgcga aggtgttact
     9181 cgttctgtat tgaaccaatt aaacaactac tttacaccag aatttctgaa ccgttttgac
     9241 gggatcatcg aattcagtgc attatcaaaa gaaaacttga tgacaatcgt cacactaatg
     9301 ctagacgatg tcaaccaaat gctggcagca cagcaacttc acatcgaagt tcctacgaat
     9361 gtcaaagaaa aattagttga cttaggctat gatccatcta tgggtgctcg tcctcttcga
     9421 cgcacgatcc aagaacaaat cgaagatggt atcgctgaat tttatcttga tcacccttct
     9481 atccatgagt tgaaagcaaa actggataaa gatggaaaaa tcatcgttac ttctaaacca
     9541 gaacgtttgg ctaaagaatc agccgaagaa acggctgaat aaatccagtt ttatagcgtg
     9601 agacggtatt tctttgagaa atgccgtctc attctttttt cagaaaagtc aaaatactgt
     9661 tcattttata aaaaagaaat tataataaga gaaacaagca attaaaaata cataaaagag
     9721 gtgagcgcca tgaaattggt aaatgtaaca aacagccatt cccgtcttgt attaaaccag
     9781 cttgaaaaca ctgatgccca tctagtcaag gtctacacag ccggaaatac cactattgtc
     9841 tacactgaag cccctgaaca taatgaaatt ctgctgatca atgacaaacg taaaatccag
     9901 ccgaaagaaa tcgaagatgc taaaaattat ttcttagata aaatcaaaga cgccgtttac
     9961 cacgaggatg aaatcaaagt aatcgaattg gcaggccttg ttgaaatctc gattccaaaa
    10021 catgaattag gcgctacatt agccgtgtaa acaaattttg aacataataa ttaaagagcg
    10081 tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcgaaagc
    10141 agaagcaact ccttcggaaa taagctgaaa ttcacgaaaa ttgcttttca aatttttgtg
    10201 aattccagct tatttcttgg agttaaacgc ttctgtctca gcctcttttt ctttctagct
    10261 ttttgatttt tctcttttct tttgtacttt tctcttttca ttttcagttc tacgcgtgtc
    10321 tttattttta actttttcct ctttatggat gattgatcgt actttttgtg caatttgctc
    10381 gtttttgtcc cagtctttta catctaataa tcgacataat cgtaacatct cttctttttt
    10441 ctgttttttt ctttcacgtc tttgccattc tgtttccatg tgtcacactc tcctttcttt
    10501 aatcatatgt acgcaaaata atttttatat ttttttgatt agacatttct atgattttaa
    10561 tatagtaaaa agagccgtca cggaaaatcc gtcacggctc taaacaaaat atgagaggct
    10621 gtttttgttt ggctattctt attacttgat gcagggcagc ttgtgtcaag acttctttac
    10681 atcaaacttt ttaattttac attgggatat ttatccgcaa accagcgttc tgcaaattgg
    10741 ttctcgaata agaacaacgg ttggtcgaaa cggtcacgag ccaagatatt gcgacttgaa
    10801 ctcatcttct catccaaatc ttctggatcg atccagcgag cgattttgtg tcccattgga
    10861 gacatgatta cttcggcgtt atactcattt aacatacgat attggaatac ttcgaattgt
    10921 agctgaccaa cagctccaat gatatattct tccgttagat atgttttata aagctgaatc
    10981 gctccttctt gaactaattg atagattcct ttgtggaagg atttttgttt catgacattt
    11041 tttgcagtca ctttcataaa cagctctgga gtaaatgaag ggagttcttc ataagcaact
    11101 tttagttttc cttcgaacaa tgtatcccca atctgataat tgcctgtatc atatacaccg
    11161 atgatatcgc ctgctactgc tttttcgacg ttttctctcg aatctgccat aaattgtgtg
    11221 acattgctta atttcagttt tttatttgta cgttccaacc agacatccat tcctcgttcg
    11281 aatgttccag aacagattcg gacaaaagcg attcggtcac gatgggctgg attcatattt
    11341 gcttggatct tgaatacgaa acctgaaaat tcttcctcat aaggacttac catctgatca
    11401 tcttgtgttt tgtgtccata aggagctggt gccaattcaa cgaaagtctc taaaaaagtc
    11461 tgtacaccga agttagtcaa tgcagaacca aaaaatactg gtgtctgatc gccacgagca
    11521 attttttctt gattaaatgc atctccagcc tctttgatta gttctacttc ttctaagact
    11581 tgttcatata aggaattttc agttagagga tgattttcgg gaagcagtcc atcttcatcc
    11641 aattctacta atcgttcatc ctgataattt tccggacgat aaaactctac acgattatgg
    11701 tagatatcat aaagaccttc tagcccttta cccataccga ttggccaatt catcggataa
    11761 gattcgatat ctaatagctc ttctaattct tctaacaatt ccaatggttc acgaccatca
    11821 cgatctagtt tgttgataaa agtaaatatc gggatgccac gtttttttac aacttggaat
    11881 aatttctttg tctgtgcttc gatccctttt gcactatcga ttaccatgac cgcactatcc
    11941 acggccatca aagtacgata agtatcttca gaaaaatctt catgtcctgg tgtatccaag
    12001 atatttactc gtttcccttg ataatcaaac tgcataacag aactagtaac agaaatccca
    12061 cgttgtttct cgatttccat ccagtctgat ttggcaaaat tacctgtttt tttgcctttt
    12121 acggtcccgg cttgacggat agccccacca aacaatagta attgttctgt aatcgttgtt
    12181 ttcccagcat ccggatggga aatgatcgca aaagttctgc gattgtccac ttgttgcttt
    12241 aattttggat tattcataac ctaactccat ttcttccatt caattattta tattttctct
    12301 aggcacagat tgtccgatct cttaaagaaa gacaatttca tatagggctg tgacaaaagc
    12361 cgtgtagcag tctctttttc cgagtaaacg gcgttctaga gacagcctat cagcaataag
    12421 cccacccaag ccaaaaatac gaaaagctgt ttttgcttgg ctgctcttat tacttaatgc
    12481 aggatagctt tttcacaacc tttgtcaact actacaactg aatcagtata gcatggattc
    12541 agcgaatgaa aaagccacca aaccataaga gtcaaatatt tttttgtcag ctgactaaaa
    12601 gaaaagacgt gttgcttgtt tattcaagca acacgtcttt cataaccaag tttccaatta
    12661 tcttcttggc tcgtcatctt cgaattcttt tctgaagtat cttcgttctt cttcaggttc
    12721 cgcttctgtt tcttccggat catgaaaaat gacacggatt ttaaggattc gagaaccttc
    12781 catttcttca gaaaccagcg taatattatc gacatcaaac gataactttt cgccttcatc
    12841 cggaatcatg cctaatgctg taatcaaata accagccatc gtatctacat cactcatatg
    12901 cagatcactg tcaaaagctt cattgaactc atcaatcagc atacgtcctt ggatgatata
    12961 ttcgtgttca tcgatttttt cataaagatt ctcaacttca tctgattcat catcgatttc
    13021 tccgacgatt tcttctaaaa ggtcttctag tgttgctaac ccaacgacgc cgccatattc
    13081 atctaataaa atagccatct gattctgcgt ctttttcatt tcatataaca gatcatcaat
    13141 aaagaccgtt tcaggaacga ataaaggctc ctgcatgatt ttcttgatat ctaaattatc
    13201 aaagccgaat ttatgggcag cttttagtaa attctttgta tgaaggattc cgactacttt
    13261 atctttgtct tcgttataaa cagggattct tgaatagttt tcggataaaa cttcattcac
    13321 attttcttcc acagtgtcgt tgatatcaat cataaatgca tccgttcgtg ggaccatgac
    13381 ttctcgggca actttcgtat caagagaaaa aaccccttgg agcatttcta attcttcatt
    13441 attcaatacg ccttcgtttt caagcatata acgcatttca tctctggtca tttttgaatc
    13501 ttcatcatca aaagtcatcg gcgtgatacg cgccaataaa cttgtggaag cagaaagcag
    13561 ccagacgaag ggcttagcta ctacaccaat caagcgtatc agccctgaag tgaactttgc
    13621 gacttcttct gatttattta aagcaatacg tttagggtac aattctccaa aaacaatcga
    13681 tacataggtc aaaatagcca gcacaatgat atttgcaata ttttttgccg ctgtgccgcc
    13741 acctaatacc ggagctaacc gttccgataa agtattagct agtgaagcac cagacaaaat
    13801 gttgaccaaa gtgattccta cttggattgt cgataggaaa ttatttggat tctgcaatat
    13861 ttttaaaagc ttttgagatt tcacatctcc ttcatcagct ttttgctcga ttcgattctt
    13921 attgatcgaa acaacagcaa tttcggaagc tgctaaaaaa gcattgatca atgtcaaaac
    13981 gatcaataat aaaatctgcg ctaacagcga ctgactctca gggtcagcat tcataatcgc
    14041 attctctcct tataaaatta atttttagtt tacgatagaa aaaaacgtgg cactatagcc
    14101 acgttaaaat ggtatcacaa agcaattttc tttgcaataa aaacaagtgt actaaaacta
    14161 cctacgaggt cgtagcaatt ttcttcttgt tttcattttg cttgtcttct ttgacgattt
    14221 tgattatata ggaaatgatc gtcttgcaga ttgcgtaaaa aggaacacct aagaagatac
    14281 caagcaatcc ggcaatattt ccagctacta gaagaacgat aatgatcgtt aatggatgga
    14341 ttttcagtga tttcccaatt acattaggat aaatgatatt cccatccaac tgttggacga
    14401 ttagcacaac cacacaacaa agtaatgctt ttaccggatc attgaagact gttactagaa
    14461 atgcaggtgc tagtcctaga taaggtccta aatatggaat taggtttgtc aatcccgcaa
    14521 tgaccccaaa taagaaagca taatccacac caattaccat atatcctaaa aatgtgaagg
    14581 taccaacgaa taaacattcg attgcttgtc cgctaatgta attagccaat gttttattca
    14641 gttgccccaa taactccaca atttggtttc ttcttttttc tgggaaaaac tgttggatgt
    14701 ttggcactag tttttctccg tctttcaaca tatagaacaa gatgaatggt gctgtaatga
    14761 ttactacggt tgccgaagcg atcgttccaa cgatcgaacc taaactattg gatactccac
    14821 taaggaattg ctgaatgatt gtcccgtaag aaatgtctaa ttgctcaaaa tatttattga
    14881 tatctacttc cttgaacaaa ggcaattcgg ctacctcttt taaccagctt tctacctgtt
    14941 tgatgaaatc aggcatatta gatgccaatg aggaaatttg ctgtactaga cttgggatga
    15001 cactaagtaa aatccaaata attgctgcaa ctaaaaggag cagcacaatt gcgacagccc
    15061 atattctttt gatttttgct ttcatcaaca gcttgacaat aggattcaat aaatagtaaa
    15121 gaaagcctgc aatcagtaca ggtgcaaata acgtggaaaa aaatgtcccg atcggttcga
    15181 aaataaagtt tatttctgat gaaatcatga tcaatgcagc tatgatcaat aattcaagcg
    15241 accaaaacat tagtttagac tgtctaagtt tttcaaacaa tagatttcct cctttctttc
    15301 ttactagtat atattatatt cgttaaaaat tcttttattc tttttttatt tttgaaaact
    15361 tgccatactt tttatttgtt ttattttcca gtatactata cgaaaggaag gtggctagac
    15421 catgaaagtt gtacaaacaa aagatacaat gagcaatatt tacttagatg ctgtacggat
    15481 caggcatcaa gtttttgtag tcgaacaggg tgtgcctttg tctcgagaaa tagacaaaga
    15541 tgaagcccat tgtatccact tcgtcctgta ctcagataaa aaagaaccgc aaggaactgt
    15601 acgtcttttg cctttagaaa acggaaaaat gaaattacag cggatggcga ttctttctga
    15661 atacagacac caagggttag gaaaaatatt gattgaagaa gcagaaaact ttgctaagaa
    15721 tcaaggctat aatacgattt tattaggggc acagtccaca gctgaaactt tttacgaaaa
    15781 actaggatat acagcttacg gcgatccttt tgaagatgct ggcatgcctc atatttatat
    15841 gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa
    15901 aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt gcttgtaacg
    15961 gttataccaa atatcaatat agccttccga gaacgggcca tctccattat tgatccagtc
    16021 aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcgggt aattcatcat
    16081 tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt caggaaatac
    16141 cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca aaaaaggtga
    16201 agctagatta caataatagg aaaccccctt ttctctgatc attgctatta cattgaacca
    16261 gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga
    16321 ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg tttttaatac
    16381 catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac
    16441 aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat tttgtgcttt
    16501 gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa tgagctttgc
    16561 ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt tcatttggac
    16621 cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag ttttgttctc
    16681 ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa catgccattt
    16741 cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa caaagagttc
    16801 ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa acagatcgat
    16861 ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg tcacttccat
    16921 cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt caaaataata
    16981 cgctccagaa tgattttgaa gagctgcact gatataataa acgtcttttg gctttgcttt
    17041 ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg
    17101 gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac ctagatccat
    17161 cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca tcgcttcatc
    17221 aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca atctgctgac
    17281 tactcgcatc acgttgccgt caactgcagg ttctggaagt ccaaatgcga tacttgcaat
    17341 cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag gcgtttgcgg
    17401 catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt tccgggctct
    17461 tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag catttgctag
    17521 ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca ctgtgtctac
    17581 tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac gattatagcg
    17641 ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt gaaattcttt
    17701 tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc ttttccgtaa
    17761 tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc tttactttta
    17821 gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct ccttgtttga
    17881 ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagct atcgcttgtt
    17941 ggatcacttc ttgagaaaag cctttcgtca tcaatgtttg ttggattttt ctcaataatt
    18001 ctttttggct ttttccgtga ttttttccaa acgctttttc ggctgtctga tgtgcatttt
    18061 gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca ggtttcaaac
    18121 ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag cgcatattcg
    18181 tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct tttaagcggg
    18241 ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat gttcggattt
    18301 ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa ccgaaatcag
    18361 ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt ccttttaata
    18421 atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca gataaatcta
    18481 cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata aacatcctcc
    18541 tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat tatatgttag
    18601 aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt gtcaaaactg
    18661 gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga atcggttatt
    18721 tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta ctagtgaaaa
    18781 tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa aaaacaagca
    18841 aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt caattacaac
    18901 acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa gcattggaaa
    18961 aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg atggatgagc
    19021 cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag actcaaaaaa
    19081 ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca gactgcttgg
    19141 ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg aataaatttg
    19201 atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc atggttagaa
    19261 tcggtgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa aaattcccgc
    19321 aaaaaaacgc aatgatccgt gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc
    19381 aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc cacttatggg
    19441 gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct cctcgtgcct
    19501 tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc aaagcattag
    19561 atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg atcggcttaa
    19621 gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa gcaatcgctg
    19681 atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa gtcgggacag
    19741 cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt atcatcgtag
    19801 atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa taccctccaa
    19861 aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg gttaatttaa
    19921 gtaaaaagtt caagattgaa tatttacagt ccgtcgacat gtttcctcag actgcacgtt
    19981 gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt
    20041 ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg ttttatgaat
    20101 actgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa aagggttgtg
    20161 acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct atcacttgat
    20221 aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta tatccttttc
    20281 gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt gctttgtcgt
    20341 ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga ttccaagttg
    20401 gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa ttccaagtaa
    20461 tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc tgttcatcta
    20521 aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat gtatttttgg
    20581 tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt aagtttcctg
    20641 ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca tgcgcaaaac
    20701 ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat aacgtactaa
    20761 tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct ttattgtatt
    20821 aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga
    20881 tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag aatcaaatca
    20941 tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt aataacaaca
    21001 attatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga gccttcatgg
    21061 taaactaata ttatagaaag gagttagtaa aatgaagatg ataaaagata ttcgtttttg
    21121 ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta gcggaaatcc
    21181 cggaaaatat tactattctt tgcaacttcc accatttgca ccacctagct ggatatttgg
    21241 gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt tacttaatca
    21301 caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt tcatttttaa
    21361 ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag caatcgatat
    21421 tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctgc atcatcgcct
    21481 ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc tattgaatta
    21541 ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta acacatagaa
    21601 aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta ttaaccaaac
    21661 tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat aaccataacc
    21721 attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg gtgtatagta
    21781 ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact gatcatatgt
    21841 gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat caccgtttgt
    21901 cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat ttttcaaatt
    21961 aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt ggatcgaaag
    22021 aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc cttcgccttg
    22081 caactggtct tgtttgattg tttcaaacgc cggggtgtag ttcgtcgcta catcaagcat
    22141 gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa tttttctata
    22201 attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta cttcccgctg
    22261 acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag aataggctaa
    22321 acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat ccaaagtaaa
    22381 gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt ccatgccatc
    22441 caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa ttgaatccat
    22501 ggccatttcg acaccaccaa atgcgtaggc atgatttaat ttatctaccg ttccataacc
    22561 tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt tttgtttcgg
    22621 attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc ctaatccacc
    22681 ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc ttactctctc
    22741 agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg tttggctcgc
    22801 ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa cgaatacccc
    22861 taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt tcacattttc
    22921 taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc ataagaaaac
    22981 tttaaaaaac atttttgtgt aacgattatt attttttaaa atttctcaaa attcttaact
    23041 atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc aatcgtttta
    23101 tcttttttta tgtatttttt ccagaaaaag cgaacaacaa ggtattttcc aaataatcgt
    23161 gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc taccgttcag
    23221 attatcattc gatttcacga caatttcttc ctatgactgg tccttttgtt aaacccatct
    23281 tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa ctagtgattg
    23341 cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac gattttcttt
    23401 taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac aaatggtctt
    23461 ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa gaaaatgttc
    23521 cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt agccaaaaaa
    23581 tctaaaaact tcataaatag acaaaaagac acgactctct aagaagtcgt gtctttattc
    23641 aacaaattat tataatttag tcacttcagc agcttgaggt ccgcgtgcac cttcaacaat
    23701 cgtgaattct acttcttgac cttcttctag gctcttgaag ccgtctcctt gaattgctga
    23761 gaaatgaaca aatacgtcat ctccgccgtc tactgtaata aacccaaatc ctttttcatt
    23821 gttgaaccat ttaaccgttc cgtgttccat aaatgtatat cctccaaaaa agttcttgca
    23881 agtaaccttg caagaacatt atacccaatt tagaaaacgc tagcaagctt tcgctctttt
    23941 attttccaaa ttatttttaa gactgatatg acggaggaaa tggttatttt gctgcttcga
    24001 aacgtttgtt tacttcatcc caattaataa cattccagaa tgctgcaata taatctggtc
    24061 ggacattttt atatttcaaa taataagcat gttcccaaac gtccaaacct agaattggtg
    24121 tctttccttc catcaatgga gaatcttgat ttgcagtaga ggtaatagct aattttccat
    24181 tttccattac aagccaagcc catccagaac caaatcgtcc agcggctgct tttttgaatt
    24241 cttctttaaa agaagaaaaa tcaccaaaag cttcattaat cgcttctttt atttctcctg
    24301 taggttcgcc accagcattt ggtgccatga tttcccagaa aaatgaatgg ttagcatgtc
    24361 cgccaccatt gttacgtaca gctgtcttga tatctgttgg aatagcgtcc atatcagata
    24421 ataattcttc tattgttttt tcgcctaatt ctgggtattt ctcaattgct gaatttaaat
    24481 tcgtcacata agtattgtga tgcttatcat gatgcagatg catcgtttct tcgtcaatat
    24541 aaggttccaa tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc ataaaaaaat
    24601 tcctcctcaa tgttttctta ataatgtcta cattacaaag agtaacaaag agaaggaaat
    24661 tcttcaattg ttatgcctag tcgtcttttt cactttgacc tacttcttct tcaaaaacct
    24721 cagtttcttt aaaaataaac aacttgctga aaatatagtt cgcaaggata acaataattt
    24781 gagtgatgat tttcgccaca tactcattgc tgttcataac attgatcaac aataccattg
    24841 cccccatgtc caatccgtaa gaaaggatac ggtagaagaa gaacttaccg cattcaataa
    24901 gtgcatgtgt aaaattcggt gattttgaat ggaataccca aagtttgttc gttacaaaag
    24961 caaacaatac agaacaaaac cacgaaatag aattggataa ggccatactt aaatcaaaat
    25021 attggcgtgc gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca ccaaaaaaga
    25081 gatagactag tatctcccaa tatccttttg cttctaaata tccttttaac tgtcgatact
    25141 gcttcatgag ccaacctacc ttattaaaaa ttcttattta tcatactcta tatttcaata
    25201 actttcatct ttatttaaaa aaattaattt tttttgatcc tttgcctttg tctctgcttg
    25261 gatcgtcaca tgtgtaatac catattttaa ttttaataaa gaaattatac gaggatatat
    25321 cttttcaatc tcgcttagta gctgatcttc aaaatcaata tgtccgtcga aaataattat
    25381 cttttcgcta tactgccaaa tatggacatg atgaacatcc tttaccccat cgattgcttc
    25441 aatttcttgt tccatttttt catagtcgat agcaggtgca ctttgtatca aaatagcggc
    25501 agcttttttg atcaccatta tcgcttctat caatatatat atcgaaatga tcagtgtaat
    25561 aactggatcg atccagtaga tatcgaaaaa acggatcaaa attgctccga taatcacact
    25621 taccgaagac agtgtatcac ttaacaaatg caaataacta gattttatat tcaaactttc
    25681 atctgcttct tgtcgtaata ataatactga gaacaaattc gcgagcaatc caataactgc
    25741 tactgttagc atcaaatgac tatttatctt ttctggtgaa gtgaaccgct tgaatgcttc
    25801 aacggttaaa aacaaggata atatgatcaa tatgaatgag ttgatgaaag cactcaatat
    25861 ttctaaacgc tggtagccat acgtacgttt tttatttgct tcttttcggg ccattttttg
    25921 tgccccgtaa gaaaaaataa ttgccaatgt atcactaagg ttatggaaag catctgaaac
    25981 aagagacaaa ctccctgaca taatccctcc aataaattct gataaagtga tcaccgcatt
    26041 caaaaccact actccaaata gtttttttga tgatctctgt ggctgtgtag gcactattcc
    26101 ttcctccatt ttatttatat tggatagtct ttagacaaga ataacatttt tttgatattt
    26161 caccaatcat tcagctgttt ccttaaagca cttgtatttc acttgatact tcgctagaat
    26221 tgcaagtgat gacactacta gatgaggagt acttatgaca acaaaacaat taattatcag
    26281 ttcctttata cgattcaaag acctaaagga ggcgagaaat gtcccatttt ggaaagccat
    26341 tgtctatctt ttagttttga gtataattat ggctttgcca atctcttttc aagtttttca
    26401 agtcttaaac aacattcaat tggatgggca aaagattgct actcgcattc ctgattttac
    26461 aatccaaaac gggcagcttc aaaccgaaga aaaagaagga ttcatttacc aaacaaactc
    26521 cattatcttc acatttgatc cagagggaaa acgaacagaa caggacatct ctactgattt
    26581 gatggggaat tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag ctcttcctaa
    26641 tacaggcacg acttctgctt tgttgaacaa taaccaatta gaacttccct acaccaatga
    26701 atctttaaaa aacttaacag gtaagcagct ccgttctttt ttaagtgaag catctatacc
    26761 actttggata aaagtcctga catttatatt ttctatttat cctagttttc tgaatctgct
    26821 gatcactttg ctatttacca acattgctgc ttttctctat gcacgctttc gactaacaaa
    26881 agctactttt cttgattgtt taaaaacatt gatctattca atttcattgc ctactataat
    26941 tgcaacaatc ttgatggtct ttcttccttc ttttgacact agcgccttca ttgcttttgc
    27001 aggaatcttt atttttgctc aagctgtcaa aggatgggca aaaatatcga tcaattaaga
    27061 aataaagaca actcgttatt tctacttcaa tagacccttt tagaggttgt gacatttttt
    27121 tgtcacagcc ccttttttat ttgaaaaata tttctttctc aaaaaacaag caaggcgctt
    27181 caaagttctt cttgtatgcg ctacacttag agtaaagaaa ggcgggaaat taactatgtc
    27241 agaaagaatc atttatgcag atcgtccatt tcgtgatgaa tttatcgaag aaatccatac
    27301 tatagcgcct ggttatatct ttaaaacaga attacaacca gaggatctac aaaatgtaga
    27361 gatcagtttg ggctggaact cagactacca agaaaaacta ttagcctctt ctaccttgaa
    27421 atgggtccaa tctatctcag ctggtgttga tcagctaccc cttgagactt tttcaaagaa
    27481 acatatttta ctttcaaatg gtagtggcat ccacagtgaa tcgattacgg agcatgtctt
    27541 aggaatcatc cttgggtatt ctcgtggtct ttttcaagca caaaaggcac agagtgacat
    27601 gaaatggtta ggttcatcgg tccattacca atctatccaa gggaaaaaaa tactaatcat
    27661 tggaactggc catattggaa aaatgattgc aaaaaaatgc aaagcattag acatgaactg
    27721 ctatggaatc aatacatccg gtcatccagc agaaggaatg gaaaagactt tttctttaaa
    27781 tcaactaaag gaagttcttc ctgaagtaga tttcgtagtc aatatcttac ctctaacgga
    27841 ggaaacaact gggctctttg atcagcatat gtttgaacac tttgatccaa aatctgtatt
    27901 catcaatgtt ggccgtggtg cttctgttaa gacacaagat ctggtgcagg ctttaaataa
    27961 ccagcaactt tcctttgcag cattagacgt ttttgaggaa gagcctcttc cacaagatca
    28021 tcctctttgg aaaatggaca atgtactgat tacttcccac attgcaggtt tgacacctga
    28081 ttttcaaaag aaattaatgg ctattttttt aaccaatctg aaaagctact ttgccaccca
    28141 tgagcttcaa accaatcaag taaaattgtc tgcaggatat taatagctga aaacaatatt
    28201 ttcaaaagaa aaaagagaag gtgacaaaaa ttgtgtcacc ctctcttttt ttattgtttt
    28261 ttaaagtgat aggttggctc ctccaggttg ggattataat caacaagtaa atcatatcct
    28321 ttaaagaacc attcatctgc ttcctcgata aaaaaaagtg tcccatcaat ttccactttc
    28381 tttacaggat gttctggctg ttcaactgac attccaatcg aaaaaccatc atgaacctct
    28441 gttttgccgt agacttttcc aaaaaaacgt attccgtaag tttctggcag atcaatttct
    28501 gagtcaaacc acttttgtgc ttttggcgtt accgttaatt tcatcccaac aacctacttt
    28561 ctcttttctt tctattgatt catcttatcg tctagaatat ccacatcgcc tgtctctcca
    28621 ataaccagta gattatcatt ttcacgaaca tattcatctg ctgcaggaga agcgataacc
    28681 gtttgatcta ctcttcgtat ggcgactact gttaagtcaa aacgttgcct gaaatttaat
    28741 tcagctaatg ttttgttgaa aaatttagga ttggagactc ggatttctgc taaagaatat
    28801 ttatctgaca actctaggta atctaaaata ttctttgaca ctaaattatg cgcaatcctt
    28861 attcccatgt ctcgctcggg atggacgacg cgatcagctc cgatcttttc aagtactctg
    28921 gcatgatact cattttgggc ttttgctaaa atatttggta cgcccatttc ctttaccatc
    28981 agagtaacta agatactggc ttgaatatct tctccaatag cgacaattac atgatcgaaa
    29041 tttcttatgc ctaatgatcg aagtgtcatt tcatcctgtg catttgccac aacagcatga
    29101 gtggctatat tcatatattc attgacccga tcttcattac tatcaatagc cagtacttct
    29161 tgaccagctt cgatcagtgt tcggcagata cttccgccaa atcgtccaag acctacaatt
    29221 gcaaaatttt gtttcaccgt tttcctcctt tagtatcttc ttttctcagt ataacaaagc
    29281 ctttacaaaa acaaaagcaa gcatcattat tgtaaaaaag ccaagaaaaa taatagttat
    29341 tttctcagct tttgattatc ctctttatca tcgtttttat ttcaccaaac catgtttgaa
    29401 tgcatagata gcggcttgtg tacggtcttc cacttctagc ttagccaata tattggaaac
    29461 atgtgttttt actgttttca gtgtaataaa caattcgtcc gctatttcct gattactttt
    29521 tccttcagaa atcagcatta aaatttcatt ttcccgattc gttagttctt catgtaatac
    29581 aggctcattt cgccgactca ttttttccat catttttgtt gtcacttctg gttctaatac
    29641 tcgctcgcca cgttgcgttg cccttatagc atcagcaatt tcatgtgcgg tagaggtctt
    29701 caacaaatac cctgctgcac ctgcttcaat ggcaggataa actttttcgt catcaataaa
    29761 actggttacg ataatgattt tagcttctgg ccaatctttt aagattgctt ttgttgattc
    29821 gataccatcc atttcttcca tgactaagtc cattaaaatg acgtccggtc gaagtgtcat
    29881 cgccttctca tagccttgtc gtccattttc agcttctcca attacttcaa tgtcttcttg
    29941 aatagataaa taaaaagaga cgcctaagcg caccatttca tggtcatcta ctaataaaac
    30001 ttttatcatc cttatctatg cctccttcat caaagggacc ttgatttcta cacttgtacc
    30061 ttgaccttta aaactaatga tttttactgt tccaccaata ccagctactc gttctttgat
    30121 attgttcaat ccataacttc ccgttttcgt ttcattcata ttaaaccctg ttccgtcgtc
    30181 aataatacgt aacaaaagat tattgtctat tttgtgcaaa tatacctcta attcattggc
    30241 tttagcatgt cttaatgtat ttgataacaa ttcttgaacg attcggaaca agtgatcctc
    30301 aatggaacta gatagtttta catcttctac atcccatttc agcgaaatct ggattttatt
    30361 ttgcaattcc ttcaataact gctcgatacc ttgctttaaa cttttctctt ctaaattgac
    30421 tggacgtaga tgaagaagca gcgcacgcat ctcagactgg gaagcgttga tgatctctgc
    30481 taccattttc aactgcttgc gaaacatttc tggtgtctcg cttttttctg cttgctccgt
    30541 caatgccgac atcatcatca ttgctgcaaa caattgttgc gaaactgaat catgcagctc
    30601 acgggctaat cgatgtcttt ctaattctaa aatttcttct ttggtttgtc catctacata
    30661 ttggggacgg ctcgttacaa tttgtaattc actagatact tcaatcattt tttcttttat
    30721 cttagtgatt tccttatcaa tatctttgat gtataaatcg tccgatgcac ttgggatcgg
    30781 aagaagcaac aatttggatt cataattgcc agaagaaagt gcacgcagct tttcttcgat
    30841 tttcccgtat tttgtctttt gaataagtga taataataga aagacaatta atcctacacc
    30901 taaggaaatg gctaacaaat ggaagataag cggaacatat aataaacgtg cacgcagtaa
    30961 ttctccccac caatgacttt gattgctggc ataaaaataa gtgaaaagtg aaaatagaat
    31021 aataaggaaa gccgcaatcc ccgaataaac agctagcatc gctctggata tttttcccat
    31081 catattcgta tcacctcgac atctccaatc aaggtattag taataatctt caatctacga
    31141 gggttttcat cataatcact gctgtagatt ttgatttgtt catttttcaa agaaaattgc
    31201 tcttcttcaa acaagacatt tcctactaat gtcgcatgct ctaatcggat ggctacgccc
    31261 aaaggtacta agatccgtgt tctgcctatc ccttttctta caatcacaat attatcatct
    31321 tttggcaaaa gcgtattgcc caaatctatg atagtatcac cagaaatgac ggcgatgttg
    31381 atatcgtccc attcatagac gtcgtttcca atacgttggt taccgaataa ttgctgtctt
    31441 ttccgctcat tattatgtgt ttttaattgc tctgtttgga tcatcatgat ctgtttcttt
    31501 cgccaaaaag catttttggt taaatctatc cctgaaatct ctacaccttt cagaccaata
    31561 aataaaacgg caaatacagc catcatccat aaagcaggac tgttgactaa gctaaaaaaa
    31621 atgaccaaac ttcctaatat caattgaaaa ttttgaaatt tagtacgagg atgtttgcgc
    31681 atagctagat atatattgaa aataccgaat atcactaaaa gcaaaagtcc agtattgttt
    31741 acgatttgcc aaacagcaaa taacagcagt agtgcttcaa ctaccacaaa aaaacgccaa
    31801 gaactattca tcgctctttc tccctcctga cacattctca tttcatcata cctatttttt
    31861 taactgttgg ctataggact ttagatgtaa gatcgtttgt tgaaatctaa aatacacaaa
    31921 gagaaaaaga tctagagtgt atcatcagta agatgaactc tctagatctt tcagtcagac
    31981 tacgcttgtt ctactttgac gattttaact aacatatcgc cacctggagt agcaatagtt
    32041 acttcatcat ttttacgttt gccaatcaat gcttgcgcaa taggagaatc attggaaatt
    32101 ttgccagaaa acggatctgc ttcagcgctt ccgacaatcg tgtactcttc ttcttctcca
    32161 tctggtagtt cgatgaatgt aactgtttta ccaattgata cctcatctgc atctacaccg
    32221 tcgttatcga tgatttgagc aaaacgaatc atattttcaa ttgttgtgat tcttccttca
    32281 acaaatgctt gttcatcttt cgctgattca tattcagagt tttcggaaag atctccgaaa
    32341 ccgcgggcaa ttttgattcg ttcaatgatt tctccgcgtt tgactgtttt tagttcttct
    32401 aattcttttt ctaatttttc tttaccttct agagtcattg gataaacttt ctctaccatg
    32461 tgtaacgtct ccttttttcg ataaaatacc gcaaaaggta atcttttgag gaatatagtc
    32521 caaaaaagat taccacgctt ttcttcaaat gtaaatgttt ttctaaaaat gatcaatgtc
    32581 tagagcctgt ttttctaaga attatttaca tatttttcca ctaattccat atgttcttca
    32641 taagttttag cgaaataaac atttccagtg ctcgtatctg ctacgaaata ataatagtca
    32701 ttttctgctg gttctaatac tgccttgatt gcctcttcgc ttggattgtc aaaaggtcca
    32761 ggtccatagc cggtattggt atacaaatta tatggtgaat ctacagctgt atcttcatac
    32821 gtcactaatt ctttgtgttc acctaatgcg tataaaacag agatatctga ctgaagtggc
    32881 atatttgctt tgattcggtt aaagaagact tgtgcaatgt ttttacgatc attttctttt
    32941 acgccttctt tttcaactag agaagctaga gttaaaactt cttgtacagt caaatttttc
    33001 tgcttgatag ctgaataata gttttgcatg accgtattcg tcttgttcac catttcaatc
    33061 actagatcct taagcgaagt actcgtgtaa taatcatatg tggctgggaa taagtaacct
    33121 tccaaacggt attttgtgtt ctcagcttta gatgcacttt ccaacagttc tgggaatttt
    33181 tggtgcaact cgttaaagaa agtctcatca ttcactaaat ctaaaaattc tttcttgtct
    33241 ttaccagtta ccttcgctac ccgttcagca atctgatcga tatcgtaccc ttctggaatg
    33301 gcaattttcc catctgcaac ttttgttggc tcagaagtac cgccttcttg caactgtttg
    33361 ccaatctcgt caagagtcat attaggcgct aactgataat agccagcttg aaagccagtt
    33421 aaatttttaa attttgtata ataattgaaa acaatcccgc ttttaataat attgtccttc
    33481 tccaaaatct caccaatctg cttgttagaa gagccactcg ggatctcgac ttggactaat
    33541 tggtcatctg atttatctaa aggcttcaac ccgctatcta cataacgata cacggtaaat
    33601 ccaagaaatc cgccaataat caataatgta agagcaatca ctaaaatgat cttcctcaca
    33661 atcttatctt cttttttacg cagatttctc cgcttgtcga ttatatctgc tgtagctgcc
    33721 ttactggctt cttttttatc tttacttggg tgttgtttgt ttcctgacaa aacaactcct
    33781 ccttactatc aagttcgtaa ctttattcat tatacatgat atttgaattg gcgtgaatga
    33841 ttttatttaa atattctatc aaaaatgtaa gtagtaaatc cattactata agattaaaat
    33901 aaatgttatc aagatacaag ctattttagc tttattcttt ctgtaaaaaa gaaaggagac
    33961 taaataaact attatgaaaa aaggaaaaca tgctaaaaaa agaaaatatt catttttaat
    34021 gatcgttgtc gtgttgttta gccttagtgc gttctctaca ggaactattc ttggatggca
    34081 attttacaat aatgaacact ctcagatagt tgcccatgct caatcagctc aaaaaaagtt
    34141 gatactgact accaatgaac aacagctcgt tgaaaaaatc gatcaactat taagaaaaaa
    34201 tgattatatt ggctcaattt acgtaaagaa aaataatcgc atcatcatgg aaaaaggcta
    34261 tggctatgcg aataaactca cgcaacaacc aaatgatcct tctctttatt atcagattgg
    34321 ttcggttcaa aaagcattga ctactctttt gattttaaaa caagtcgagc gtgggcacct
    34381 ttctttagat actaagctgg ctcaattcta tccacaaatt gctggcagcc agcaaattac
    34441 tatccgtgac ttgctgtata tgcgctcagg cttgcaccga actgcttctc caaccatacc
    34501 gatgactgat gaagaagtcg ttcaatttgc gattcagcac ttaaaattta cagattatca
    34561 gacctctcat tatgattcat tgaactttac catattgact ggaattttga tcaaattaac
    34621 aaatcaaccg tatgaaaaat tattgaccga tgatatcatc gaacctttag gattacagca
    34681 tacaaaattt tatgaccaag tcaaaaattc atccaatcat gcactatcct atcaaatgtc
    34741 taaagaggat gattacttta aaccactgac agaatctgaa acagagatcc ataacgaatt
    34801 agggactggt aatatcagta tgtccgtcta tgatttaaat acgctgttta cacaagtttt
    34861 atctggaaaa ctagtttcca aagacttact cttctcatta tggcgtgaaa atgcgaatgg
    34921 acatccatat agtggtgggg tatatagcgg agataattat atcctgtcgc aaggaaatat
    34981 cgactctttt gatacatctg ctatatttag caaagattca caggatgcta tcatcatgga
    35041 aagcaatata aaagctgaca aaactatcaa actgcctact gctgatctaa gaaaccaaat
    35101 ctatgacctg atggaaggaa ctactaagtt ggcaaatagc tgatatgatg aaaagatagc
    35161 aaatactact tctttgaata gcatttgctt aaaaaaagta ctcgactaaa cgtaggaaag
    35221 agtgtgggac aaatctaaaa atcaattttt gctacagact ttaattccaa ataaacagaa
    35281 cagaaagagg tgttcttctt tctgttctgt ccaaattatt ctaagatttc tctttaccaa
    35341 cattatttga caaagggcct attaaatcta aaatagtatc tttagattgc taaaatatgt
    35401 gctagcaaat cattcatggc ttgttcttat ttttaatttt atgcaataaa aaagaagaac
    35461 aattagcgtg attatagaaa taaataatga gattttagaa aaaaatgtgt atgaatacct
    35521 gattgttact ttatttattc cactttcact ttttactgta acaaaaggac ctccttgttt
    35581 tagtactgta gcattttttg aattaacagt aaccgttaat cctttatacc ggaatacagg
    35641 taaaactatt gttttgcctt ttgaagattt aaacgtaaat gtaatttcat ctttatttgg
    35701 agaaaagcta ctataaataa cttgaccatc ttctgtaact tgatggtttt tcaaaagcaa
    35761 ttgatctttt ttatagccta taggtacata atcaaaattc tcaaattctt caagtttatt
    35821 ttccatttgt tcattagaat aagttccttg aaaattcatt tctttcacca tgttaactac
    35881 tgatgaataa tttaaaattg aaatagctaa tattaataat agtataaaat ttcttctcct
    35941 tgtataagaa aatttttcca actgtggaga aataaataga gatactgaaa aagatatgaa
    36001 caatgttgaa aatatcataa aacgccaagg agcttgaata atatttaaag gagtattttg
    36061 taaggcaaac catggaaata tttttgtaca aagtagaata gatattatac ccattatata
    36121 agtgatttta gataagattc ctaatttttt aaagttaaat gttagtataa ttaaacaaat
    36181 aagcaaagtt aagccaatac caaatgatag taattctgaa tctatacttc caatcaaaaa
    36241 ctctttaccc agataaattg ctcttttttg taatatatcc acataaggtc tattcagatc
    36301 ttgatacaat gtctgctcaa tcataggacc tataaacgct agtgaaagaa gtaaagtaac
    36361 tatagcagct tttattaatt taataattaa gaagatttct attttctttt tccgataaaa
    36421 ttgaataatt aaagcaatta taatcattac catagtcata gctacagaaa gaacatgagt
    36481 gtaaattaat aaagtcatgc taatcgccaa cataacccaa gattcttttt ttgagtcgta
    36541 aagctttata aacccgagta aaataagagg aagtattgac attgcgagta attcccccat
    36601 tgcccctcga agaaatattt ctacactcct aaaagaagat gttgtatata taatagcgaa
    36661 aaaggagcta gtaacatgtt ttttggtaat ttcatacatt acataatgac atataaatag
    36721 agtaatgagc gtaacaatat aaagaaaaag gttatagcct attgctaaat tagtaaactt
    36781 gatcaataaa aataaaggat atagagttaa ccatgggtaa aaattattta cttgcatgcc
    36841 atatgatcta aacgtttcaa aattaatagg ggagctaaaa atagattcta aacttaacgc
    36901 acgattaatg tgaaatgccg tatcataaaa gccaaatatt tccatgtttt taaatgctgg
    36961 aaataaatat aataaactaa caaatgcata aactataaat atttttacag aaaaaatttt
    37021 tttcaaattc atataccacc tcatgttttt ttatattaca tatagtatca tttatttttt
    37081 tt
//
LOCUS       DACCVH010000019        37064 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.019, whole genome shotgun sequence.
ACCESSION   DACCVH010000019 DACCVH010000000
VERSION     DACCVH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.019"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            299..1960
                     /locus_tag="IVV98_001016"
     CDS             299..1960
                     /locus_tag="IVV98_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7806690.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="IVV98_001017"
     CDS             complement(2030..2392)
                     /locus_tag="IVV98_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP7806691.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="IVV98_001018"
     CDS             2460..3401
                     /locus_tag="IVV98_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806692.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="IVV98_001019"
     CDS             3402..4445
                     /locus_tag="IVV98_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806693.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="IVV98_001020"
     CDS             4451..5521
                     /locus_tag="IVV98_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806694.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="IVV98_001021"
     CDS             5511..6464
                     /locus_tag="IVV98_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806695.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="IVV98_001022"
     CDS             6476..7486
                     /locus_tag="IVV98_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7806696.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="IVV98_001023"
     CDS             complement(7771..8592)
                     /locus_tag="IVV98_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP7806697.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="IVV98_001024"
     CDS             complement(8689..8967)
                     /locus_tag="IVV98_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806698.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="IVV98_001025"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="IVV98_001025"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP7806699.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="IVV98_001026"
     CDS             complement(11723..12310)
                     /locus_tag="IVV98_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806700.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="IVV98_001027"
     CDS             12485..13807
                     /locus_tag="IVV98_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7806701.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="IVV98_001028"
     CDS             13962..14738
                     /locus_tag="IVV98_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP7806702.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="IVV98_001029"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="IVV98_001029"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP7806703.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="IVV98_001030"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="IVV98_001030"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP7806704.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="IVV98_001031"
     CDS             16628..17257
                     /locus_tag="IVV98_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806705.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="IVV98_001032"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="IVV98_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP7806706.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="IVV98_001033"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="IVV98_001033"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP7806707.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..19980
                     /locus_tag="IVV98_001034"
     CDS             19444..19980
                     /locus_tag="IVV98_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP7806708.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="IVV98_001035"
     CDS             complement(20020..21783)
                     /locus_tag="IVV98_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806709.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="IVV98_001036"
     CDS             complement(21786..23501)
                     /locus_tag="IVV98_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806710.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24280..24504)
                     /locus_tag="IVV98_001037"
     CDS             complement(24280..24504)
                     /locus_tag="IVV98_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806711.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24704..27472
                     /locus_tag="IVV98_001038"
     CDS             24704..27472
                     /locus_tag="IVV98_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7806712.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            27553..27972
                     /locus_tag="IVV98_001039"
     CDS             27553..27972
                     /locus_tag="IVV98_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP7806713.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27984..28454
                     /locus_tag="IVV98_001040"
     CDS             27984..28454
                     /locus_tag="IVV98_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7806714.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28471..29250
                     /locus_tag="IVV98_001041"
     CDS             28471..29250
                     /locus_tag="IVV98_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7806715.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29237..30058
                     /locus_tag="IVV98_001042"
     CDS             29237..30058
                     /locus_tag="IVV98_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7806716.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30075..31124
                     /locus_tag="IVV98_001043"
     CDS             30075..31124
                     /locus_tag="IVV98_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7806717.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31137..32141
                     /locus_tag="IVV98_001044"
     CDS             31137..32141
                     /locus_tag="IVV98_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7806718.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32774..33793
                     /locus_tag="IVV98_001045"
     CDS             32774..33793
                     /locus_tag="IVV98_001045"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP7806719.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33836..34717
                     /gene="galU"
                     /locus_tag="IVV98_001046"
     CDS             33836..34717
                     /gene="galU"
                     /locus_tag="IVV98_001046"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP7806720.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35017..35394
                     /locus_tag="IVV98_001047"
     CDS             35017..35394
                     /locus_tag="IVV98_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806721.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36000..36614
                     /locus_tag="IVV98_001048"
     CDS             36000..36614
                     /locus_tag="IVV98_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7806722.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12136 a         6493 c         7576 g        10859 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt cattcatagg
    23701 aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata tatcaagtaa
    23761 atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa tcttttttgc
    23821 tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca aagaaggagt
    23881 atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag gaataaataa
    23941 tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac gaagacaacc
    24001 tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa aagaaaacaa
    24061 ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg
    24121 tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct gaaagcatca
    24181 taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata aggatttgta
    24241 atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat ggaaggattt
    24301 atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta tatattgcgt
    24361 atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag gcaaaaatac
    24421 aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct
    24481 gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt tcatatgttg
    24541 aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa ttataaggga
    24601 taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa gattttattg
    24661 acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga agaaggaaat
    24721 tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga acgaggtctt
    24781 tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca gtcattattt
    24841 gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag tgatttattt
    24901 ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt atttttctat
    24961 cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat tctcttttat
    25021 gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag ctctttacta
    25081 tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta aaagttattt
    25141 agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt ctgcaccatt
    25201 catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta gcaatttgtt
    25261 tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg cttttgaagc
    25321 agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag aaggtcagga
    25381 aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac ctaatttgtc
    25441 acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta gtcatttctt
    25501 aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta atcagcgtag
    25561 tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa gaaaaatggg
    25621 gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga aattatccgg
    25681 aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat atgctgaaca
    25741 gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac tacttgcgca
    25801 gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc agaccttaga
    25861 gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat
    25921 cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa aattaaagca
    25981 agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag aaaaacacga
    26041 gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg aaactgccta
    26101 tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct atcagcgaag
    26161 cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag aattagaaca
    26221 acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc tggaattaag
    26281 taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga cgatctatct
    26341 aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg
    26401 ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag aggatctatt
    26461 tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag aaatccttga
    26521 ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca tgggatctct
    26581 gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga ttttgaataa
    26641 tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg tatcattaga
    26701 agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc tctatccaga
    26761 ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta cggcggtcca
    26821 cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa tcatcccata
    26881 tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca tatacgaagt
    26941 cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc tttcattaga
    27001 agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca ctactatgaa
    27061 tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat tggaaaaagt
    27121 actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg atcattttat
    27181 gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat tagcgttgta
    27241 tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg aaacctatca
    27301 aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta aatctgcgtt
    27361 tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg cctatatcta
    27421 tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt gaacataagc
    27481 aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga
    27541 ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt tgcttcaggg
    27601 atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt attcgattgc
    27661 tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat gaggtacaaa
    27721 gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa cgaattctta
    27781 caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc actattgatt
    27841 gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca gcaggtgcta
    27901 actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa aatagaagaa
    27961 gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat cggttattac
    28021 acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt ttgattgcta
    28081 atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc aagccacaag
    28141 gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa agcggggtga
    28201 cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat aagctggcag
    28261 aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa cctggtactc
    28321 gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg aaacgattaa
    28381 ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa
    28441 gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt attaggaatt
    28501 gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc tcgtccgatt
    28561 gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat cattatgggc
    28621 gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat tccacctgat
    28681 gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc cggtacagaa
    28741 accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa aaatatttac
    28801 ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga agaaggaaat
    28861 tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt gatgcttggt
    28921 gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct attaaatatg
    28981 attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc agctcttggt
    29041 tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt tttcttaggt
    29101 tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt tggtgcgatt
    29161 ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca aacaactgca
    29221 ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa cgaaaaaaga
    29281 gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt atgaacgtca
    29341 gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat atcagtcgaa
    29401 agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga ccccacatat
    29461 cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg atgatcctga
    29521 atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc ttgcagggtt
    29581 aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg gtacctcttt
    29641 agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca atattccgca
    29701 cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg gttttttgaa
    29761 aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta ttattggact
    29821 gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt taaaaatcgg
    29881 ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc caaatatctt
    29941 atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga aaccattaac
    30001 gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga ttttttaaaa
    30061 aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag gaagtactaa
    30121 gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa acagtgaatt
    30181 tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag ccagcattgg
    30241 aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc aattatggaa
    30301 aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta
    30361 ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct atcacaaatg
    30421 acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt gccggggtag
    30481 aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta ctactcttag
    30541 ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc
    30601 aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg gaagaatttt
    30661 ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt ggatatggtc
    30721 caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt
    30781 cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca gatgcttcgc
    30841 atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa aagttgcaaa
    30901 gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa gcaagaaacg
    30961 agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta gcgcttgtcg
    31021 ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac ttgaacaaaa
    31081 agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg gaaatcatgc
    31141 tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct ttacgtccgc
    31201 aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc tattatctag
    31261 gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat gggaaaagca
    31321 acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac aaaagattaa
    31381 caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag
    31441 cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat aaagcgaaca
    31501 gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga acagaacaaa
    31561 tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc gaagcttatt
    31621 cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa gcagagaaaa
    31681 aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt atgcattatt
    31741 ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt tactgggaag
    31801 aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac gggacgttag
    31861 agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa cagagagtgt
    31921 tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca ttgatagaca
    31981 caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct
    32041 tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg aactgccatc
    32101 cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg gataaaaaga
    32161 atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa atattggcat
    32221 caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata atctgtttaa
    32281 tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag ttgttgcatg
    32341 gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc
    32401 agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa tctgtccgtt
    32461 gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta aatcaatact
    32521 cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt gtcaaaactg
    32581 cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag actattgtaa
    32641 catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa
    32701 tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca attatttatt
    32761 tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt ggggcactgc
    32821 tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa atgtacctga
    32881 acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg atttgacgat
    32941 cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg cagatgctat
    33001 tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta ttggtaaaat
    33061 gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata cgcataaacg
    33121 aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt
    33181 atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa ttacagctgc
    33241 aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg attatttcag
    33301 gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga aaaatatcat
    33361 tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa aagcagcaat
    33421 catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct
    33481 gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa gtgttcattc
    33541 tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag aagttctaga
    33601 aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag agctagctca
    33661 acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt ataatggaga
    33721 agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt
    33781 ttctcttcgt taaatagatg atcaatagtt aatcgtcgtt taggaggaac agcaagtgaa
    33841 ggtcaaaaaa gcagtcattc ctgccgctgg gctaggaaca cgttttttgc cggcaacaaa
    33901 agccatggca aaagaaatgc ttccaatcgt ggataaacca acgatccagt ttattgtgga
    33961 agaagcattg gattcgggaa tcgaagacat cttgatcgta acgggaaaag aaaaaagacc
    34021 cattgaagat cactttgatg caaatatcga attggaaaac aatttgcggg aaaaggaaaa
    34081 aacagaatta ctcgctttag ttgaagaaac gactcaagtc aatcttcact tcatccgtca
    34141 atctcatcca agaggactgg gggatgccgt gcttcaagca aaagcattta taggaaatga
    34201 accgtttgtc gtcatgctgg gggatgattt gatgaaagat gatatcccat tgactcaaca
    34261 attgatgatg gattatgaag aaacacaagc ttccgctgtt gccgtcatgc gtgtaccaga
    34321 aaatgaaaca tctaaatacg gaattattga tcctaaaaca gatagcgaaa agggtcgttg
    34381 cagagtaaaa gggtttgtag aaaaacctga aatgggaaaa gcaccaagta atttagccat
    34441 tatcggacgt tatctactga ctcctaaaat atttgagata ttagaaactc aagaaccagg
    34501 agcaggaaac gagatacagc taacggatgc acttcagact cttaaccaga cagaggcggt
    34561 ctatgcgaga gagtttaaag gaaaaagata cgacgtaggc gataagttag gatatatgaa
    34621 gacaaatatt gaatatggac ttcaacattc ggaaattggg acttcattaa gtgcatatat
    34681 tatccagttg agtaaaaagc taagaacaga aagttaactg gaaataagtg gcctgctgag
    34741 aatgaaaggc tatttgttat taaagcggca gcttgtgcgt catttgcgca actgtcgttt
    34801 tagttttttg actctagatc agttgagtcg tggaaaacga aagatagaaa aagactttcg
    34861 tgaatagatt cagaaaatat tatgctaatg gtttaatttt tttttaagtt gtataaaaga
    34921 aaatgattac ataagagaaa tgaaagccaa gccagaagat tcatagtaga ataaaaaggc
    34981 gaatttttta attataaaaa aaggtgtgtg ttcactatgg gaaaattagt cgctgttgca
    35041 cagtcgctgc ttgatatact caagtggctg atggaaggaa gcaattggat atttgtgttg
    35101 ccactattgc ttattagtct atttatcatg tttcgcatgg tcagaaaaaa agaaacgttt
    35161 ctgattttta tctggtatgc agcatccgtt ggggttgcta ccttgatggt tgaattggcg
    35221 ttaggtagtt gggaagcttg cgtatttgct ttattttttg ctgtactgta tctaatcatt
    35281 tatatcccat atatgaaaag aaagtctcgg ataggcagaa aaggtagaca tacaactact
    35341 ttttctagta cagattctct cgaacaaagt agaagaacga gaagaagacg gtaatattta
    35401 gtaggtatac gcaaaaaaag ataaaataat ggataaacta ttgagatgag agatttattt
    35461 aattggtgga aaaaagcttt tttcacttat ataaaagaat cttttttaaa ggaatgcttg
    35521 ttgtatcggg ataagccatt ccttttttta tgttatttat atatatataa atcataccaa
    35581 tgtttttttg tattttcttg cttgcacttg gataagagat tacttacaat aaattcagat
    35641 agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga atcagggaat
    35701 gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc agtgcatcga
    35761 cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat attttccatg
    35821 gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc aatgcctttt
    35881 ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt ttttatgtac
    35941 ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg gagagataaa
    36001 tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg atagaagagc
    36061 cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt ggtagattgc
    36121 agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat caaaccccgg
    36181 atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa acgctagaag
    36241 gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt tttcttcttc
    36301 tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc aaagaaaatg
    36361 gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa tcgcaacata
    36421 gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac gccaatttac
    36481 atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca gcctctcttg
    36541 caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta gtccaggaca
    36601 caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa tgttccacat
    36661 aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca acgactactt
    36721 tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt ttgtttaaag
    36781 tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga atatgtagtg
    36841 tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg attctttctt
    36901 gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa gtaattatag
    36961 tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg tccaacagga
    37021 tacctttttc taatagaaat aaaatacaca aaaattgaag gata
//
LOCUS       DACCVH010000020        34959 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.020, whole genome shotgun sequence.
ACCESSION   DACCVH010000020 DACCVH010000000
VERSION     DACCVH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.020"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            156..1862
                     /locus_tag="IVV98_001049"
     CDS             156..1862
                     /locus_tag="IVV98_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP7806723.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="IVV98_001050"
     CDS             complement(2020..2922)
                     /locus_tag="IVV98_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7806724.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3623)
                     /locus_tag="IVV98_001051"
     CDS             complement(2919..3623)
                     /locus_tag="IVV98_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP7806725.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="IVV98_001052"
     CDS             complement(3654..4295)
                     /locus_tag="IVV98_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7806726.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="IVV98_001053"
     CDS             complement(4333..4647)
                     /locus_tag="IVV98_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806727.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /locus_tag="IVV98_001054"
     CDS             complement(4635..5264)
                     /locus_tag="IVV98_001054"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP7806728.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVV98_001055"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVV98_001055"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP7806729.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="IVV98_001056"
     CDS             complement(5984..6916)
                     /locus_tag="IVV98_001056"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP7806730.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="IVV98_001057"
     CDS             complement(6913..7689)
                     /locus_tag="IVV98_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP7806731.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVV98_001058"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVV98_001058"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP7806732.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVV98_001059"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVV98_001059"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP7806733.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="IVV98_001060"
     CDS             complement(12014..13294)
                     /locus_tag="IVV98_001060"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP7806734.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="IVV98_001061"
     CDS             complement(13313..14239)
                     /locus_tag="IVV98_001061"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP7806735.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="IVV98_001062"
     CDS             complement(14252..15535)
                     /locus_tag="IVV98_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP7806736.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVV98_001063"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVV98_001063"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP7806737.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="IVV98_001064"
     CDS             complement(16323..17234)
                     /locus_tag="IVV98_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7806738.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="IVV98_001065"
     CDS             complement(17231..17695)
                     /locus_tag="IVV98_001065"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP7806739.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="IVV98_001066"
     CDS             complement(17700..18398)
                     /locus_tag="IVV98_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7806740.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="IVV98_001067"
     CDS             complement(18385..18771)
                     /locus_tag="IVV98_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806741.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="IVV98_001068"
     CDS             complement(18918..20588)
                     /locus_tag="IVV98_001068"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP7806742.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="IVV98_001069"
     CDS             20771..21004
                     /locus_tag="IVV98_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP7806743.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="IVV98_001070"
     CDS             complement(21103..21534)
                     /locus_tag="IVV98_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP7806744.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="IVV98_001071"
     CDS             21613..22026
                     /locus_tag="IVV98_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP7806745.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="IVV98_001072"
     CDS             complement(22064..23212)
                     /locus_tag="IVV98_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP7806746.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="IVV98_001073"
     CDS             complement(23334..23930)
                     /locus_tag="IVV98_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7806747.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVV98_001074"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVV98_001074"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP7806748.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="IVV98_001075"
     CDS             27160..27591
                     /locus_tag="IVV98_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7806749.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="IVV98_001076"
     CDS             complement(27636..28985)
                     /locus_tag="IVV98_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7806750.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="IVV98_001077"
     CDS             complement(29055..30218)
                     /locus_tag="IVV98_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806751.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="IVV98_001078"
     CDS             30347..30670
                     /locus_tag="IVV98_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806752.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="IVV98_001079"
     CDS             complement(30853..32202)
                     /locus_tag="IVV98_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7806753.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="IVV98_001080"
     CDS             complement(32271..33224)
                     /locus_tag="IVV98_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP7806754.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="IVV98_001081"
     CDS             complement(33326..34516)
                     /locus_tag="IVV98_001081"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP7806755.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9950 a         7641 c         6120 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccga
//
LOCUS       DACCVH010000021        34772 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.021, whole genome shotgun sequence.
ACCESSION   DACCVH010000021 DACCVH010000000
VERSION     DACCVH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.021"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(227..1114)
                     /locus_tag="IVV98_001082"
     CDS             complement(227..1114)
                     /locus_tag="IVV98_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7806756.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="IVV98_001083"
     CDS             complement(1111..1980)
                     /locus_tag="IVV98_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7806757.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="IVV98_001084"
     CDS             complement(2117..3403)
                     /locus_tag="IVV98_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7806758.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="IVV98_001085"
     CDS             3676..4254
                     /locus_tag="IVV98_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7806759.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="IVV98_001086"
     CDS             4254..5183
                     /locus_tag="IVV98_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806760.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="IVV98_001087"
     CDS             5180..6916
                     /locus_tag="IVV98_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7806761.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="IVV98_001088"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="IVV98_001088"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP7806762.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="IVV98_001089"
     CDS             complement(7812..8321)
                     /locus_tag="IVV98_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP7806763.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="IVV98_001090"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="IVV98_001090"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP7806764.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="IVV98_001091"
     CDS             complement(9622..10713)
                     /locus_tag="IVV98_001091"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP7806765.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="IVV98_001092"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="IVV98_001092"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP7806766.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="IVV98_001093"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="IVV98_001093"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP7806767.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="IVV98_001094"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="IVV98_001094"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP7806768.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="IVV98_001095"
     CDS             complement(14676..15650)
                     /locus_tag="IVV98_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP7806769.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="IVV98_001096"
     CDS             complement(15631..17514)
                     /locus_tag="IVV98_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP7806770.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="IVV98_001097"
     CDS             complement(17532..19757)
                     /locus_tag="IVV98_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP7806771.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="IVV98_001098"
     CDS             19872..20906
                     /locus_tag="IVV98_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7806772.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="IVV98_001099"
     CDS             complement(20973..21986)
                     /locus_tag="IVV98_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7806773.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="IVV98_001100"
     CDS             complement(22064..22252)
                     /locus_tag="IVV98_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP7806774.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="IVV98_001101"
     CDS             complement(22692..22820)
                     /locus_tag="IVV98_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP7806775.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="IVV98_001102"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="IVV98_001102"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP7806776.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="IVV98_001103"
     CDS             complement(24307..25362)
                     /locus_tag="IVV98_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP7806777.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="IVV98_001104"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="IVV98_001104"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP7806778.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="IVV98_001105"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="IVV98_001105"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP7806779.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="IVV98_001106"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="IVV98_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP7806780.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="IVV98_001107"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="IVV98_001107"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP7806781.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="IVV98_001108"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="IVV98_001108"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP7806782.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="IVV98_001109"
     CDS             33124..34683
                     /locus_tag="IVV98_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP7806783.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9518 a         7495 c         6336 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctgggaaa ac
//
LOCUS       DACCVH010000022        34088 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.022, whole genome shotgun sequence.
ACCESSION   DACCVH010000022 DACCVH010000000
VERSION     DACCVH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.022"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(27..1259)
                     /locus_tag="IVV98_001110"
     CDS             complement(27..1259)
                     /locus_tag="IVV98_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP7806784.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="IVV98_001111"
     CDS             1514..2083
                     /locus_tag="IVV98_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7806785.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="IVV98_001112"
     CDS             complement(2261..2701)
                     /locus_tag="IVV98_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP7806786.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="IVV98_001113"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="IVV98_001113"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP7806787.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="IVV98_001114"
     CDS             3655..4578
                     /locus_tag="IVV98_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP7806788.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="IVV98_001115"
     CDS             complement(4803..5042)
                     /locus_tag="IVV98_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7806789.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="IVV98_001116"
     CDS             complement(5047..5466)
                     /locus_tag="IVV98_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7806790.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /locus_tag="IVV98_001117"
     CDS             complement(5693..6931)
                     /locus_tag="IVV98_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7806791.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="IVV98_001118"
     CDS             complement(7038..7673)
                     /locus_tag="IVV98_001118"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7806792.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7787..7879)
                     /locus_tag="IVV98_001119"
                     /pseudo
     CDS             complement(7787..7879)
                     /locus_tag="IVV98_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8015..8650)
                     /locus_tag="IVV98_001120"
     CDS             complement(8015..8650)
                     /locus_tag="IVV98_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7806793.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="IVV98_001121"
     CDS             9162..10304
                     /locus_tag="IVV98_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7806794.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="IVV98_001122"
     CDS             10297..10503
                     /locus_tag="IVV98_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP7806795.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="IVV98_001123"
     CDS             10582..11775
                     /locus_tag="IVV98_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7806796.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(11782..11940)
                     /locus_tag="IVV98_001124"
                     /pseudo
     CDS             complement(11782..11940)
                     /locus_tag="IVV98_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            11980..13119
                     /locus_tag="IVV98_001125"
     CDS             11980..13119
                     /locus_tag="IVV98_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP7806797.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="IVV98_001126"
     CDS             13112..13912
                     /locus_tag="IVV98_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7806798.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="IVV98_001127"
     CDS             13912..14739
                     /locus_tag="IVV98_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7806799.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14717..15451
                     /locus_tag="IVV98_001128"
     CDS             14717..15451
                     /locus_tag="IVV98_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7806800.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="IVV98_001129"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="IVV98_001129"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP7806801.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="IVV98_001130"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="IVV98_001130"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP7806802.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="IVV98_001131"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="IVV98_001131"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP7806803.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="IVV98_001132"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="IVV98_001132"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP7806804.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="IVV98_001133"
     CDS             19036..21069
                     /locus_tag="IVV98_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806805.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="IVV98_001134"
     CDS             21113..22393
                     /locus_tag="IVV98_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP7806806.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="IVV98_001135"
     CDS             22603..23409
                     /locus_tag="IVV98_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806807.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="IVV98_001136"
     CDS             23421..24641
                     /locus_tag="IVV98_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806808.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="IVV98_001137"
     CDS             24631..26217
                     /locus_tag="IVV98_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7806809.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="IVV98_001138"
     CDS             26256..28394
                     /locus_tag="IVV98_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7806810.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="IVV98_001139"
     CDS             complement(28762..29745)
                     /locus_tag="IVV98_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAP7806811.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30123..31514
                     /locus_tag="IVV98_001140"
     CDS             30123..31514
                     /locus_tag="IVV98_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP7806812.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31530..32570
                     /locus_tag="IVV98_001141"
     CDS             31530..32570
                     /locus_tag="IVV98_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7806813.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32589..33674
                     /locus_tag="IVV98_001142"
     CDS             32589..33674
                     /locus_tag="IVV98_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP7806814.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33707..>34088
                     /locus_tag="IVV98_001143"
     CDS             33707..>34088
                     /locus_tag="IVV98_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7806815.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQI"
BASE COUNT        11054 a         5832 c         6716 g        10486 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt aggagtgtat
    30121 atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata ttaatggatg
    30181 ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt ggagagatcc
    30241 cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg atttttattg
    30301 cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt gacatcgtgt
    30361 ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg acttttgcgg
    30421 gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc ggtacgcttt
    30481 tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt cgagataaaa
    30541 aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa
    30601 agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat gcaaacatca
    30661 aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa gaaactgaaa
    30721 aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg aatacaacat
    30781 ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa agtattattg
    30841 aagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg tttgatatca
    30901 tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca gcaattttag
    30961 tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa
    31021 aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca aaatctggac
    31081 cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt attcgagctg
    31141 tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg tcgatcgtag
    31201 gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac ccttattact
    31261 acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat ggaaaatatg
    31321 tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa tattcattga
    31381 tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa atgtcctctc
    31441 aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt ccgaatgaaa
    31501 aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac
    31561 cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa gaattggatt
    31621 atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca caggaaatca
    31681 ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc aatcaagggc
    31741 ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc ttattcttcg
    31801 atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg ctagaaaaga
    31861 gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac gagggaagaa
    31921 tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac gaagagttta
    31981 taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg aacaaatgct
    32041 atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat agttgtgagg
    32101 atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg aacccaaaag
    32161 tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac cgacctaaca
    32221 agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac gatattaata
    32281 aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt tctatttata
    32341 gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata ttgagtgatc
    32401 cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa aaaataacaa
    32461 agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt ggaagcttcg
    32521 ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag ttaatggagg
    32581 aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt ggagcagagt
    32641 ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt gattttttga
    32701 tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga ttaggaggcc
    32761 gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata gaagtgaata
    32821 agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt ggcgggggaa
    32881 ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat agccatgcaa
    32941 ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat
    33001 tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt gaaagtctgt
    33061 ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt tatagtaaaa
    33121 attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt acttttgttg
    33181 tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta gagatttttt
    33241 tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa gggtcactta
    33301 gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta aaatttttag
    33361 gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta atgccttctc
    33421 tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta aaattagtct
    33481 tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt gtatcattag
    33541 atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct aataaaataa
    33601 cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag agtatatata
    33661 gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga aaatatgtta
    33721 tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc gattgaacga
    33781 aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat ttattgaagc
    33841 atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta aaatttattg
    33901 gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat tacaaaatga
    33961 gaaatattta aaatatgtat tattatctgg tgctgattat ccaatcaaag ataatgagta
    34021 tatttataat tattttaaaa agaatagttc agtggagttt attcgtggaa tagatctaga
    34081 tcaaatta
//
LOCUS       DACCVH010000023        33823 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.023, whole genome shotgun sequence.
ACCESSION   DACCVH010000023 DACCVH010000000
VERSION     DACCVH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.023"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            53..1951
                     /locus_tag="IVV98_001144"
     CDS             53..1951
                     /locus_tag="IVV98_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP7806816.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(2281..3000)
                     /locus_tag="IVV98_001145"
     CDS             complement(2281..3000)
                     /locus_tag="IVV98_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAP7806817.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            3337..3669
                     /locus_tag="IVV98_001146"
     CDS             3337..3669
                     /locus_tag="IVV98_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806818.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            3656..5659
                     /locus_tag="IVV98_001147"
     CDS             3656..5659
                     /locus_tag="IVV98_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP7806819.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            5678..6148
                     /locus_tag="IVV98_001148"
     CDS             5678..6148
                     /locus_tag="IVV98_001148"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP7806820.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            6169..6753
                     /locus_tag="IVV98_001149"
     CDS             6169..6753
                     /locus_tag="IVV98_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP7806821.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            6768..7754
                     /locus_tag="IVV98_001150"
     CDS             6768..7754
                     /locus_tag="IVV98_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP7806822.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            7744..8055
                     /locus_tag="IVV98_001151"
     CDS             7744..8055
                     /locus_tag="IVV98_001151"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP7806823.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            8077..9858
                     /locus_tag="IVV98_001152"
     CDS             8077..9858
                     /locus_tag="IVV98_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP7806824.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            9851..11227
                     /locus_tag="IVV98_001153"
     CDS             9851..11227
                     /locus_tag="IVV98_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP7806825.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            11234..11869
                     /locus_tag="IVV98_001154"
     CDS             11234..11869
                     /locus_tag="IVV98_001154"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP7806826.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            11899..13254
                     /locus_tag="IVV98_001155"
     CDS             11899..13254
                     /locus_tag="IVV98_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP7806827.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(13446..14840)
                     /locus_tag="IVV98_001156"
     CDS             complement(13446..14840)
                     /locus_tag="IVV98_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP7806828.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            14932..15903
                     /locus_tag="IVV98_001157"
     CDS             14932..15903
                     /locus_tag="IVV98_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP7806829.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            15900..16682
                     /locus_tag="IVV98_001158"
     CDS             15900..16682
                     /locus_tag="IVV98_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP7806830.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(16851..17222)
                     /locus_tag="IVV98_001159"
     CDS             complement(16851..17222)
                     /locus_tag="IVV98_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7806831.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            17356..17799
                     /locus_tag="IVV98_001160"
     CDS             17356..17799
                     /locus_tag="IVV98_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP7806832.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(17842..18651)
                     /gene="yidA"
                     /locus_tag="IVV98_001161"
     CDS             complement(17842..18651)
                     /gene="yidA"
                     /locus_tag="IVV98_001161"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP7806833.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(18670..20037)
                     /locus_tag="IVV98_001162"
     CDS             complement(18670..20037)
                     /locus_tag="IVV98_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7806834.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(20021..20851)
                     /locus_tag="IVV98_001163"
     CDS             complement(20021..20851)
                     /locus_tag="IVV98_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP7806835.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            21014..21451
                     /locus_tag="IVV98_001164"
     CDS             21014..21451
                     /locus_tag="IVV98_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP7806836.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            21527..22147
                     /locus_tag="IVV98_001165"
     CDS             21527..22147
                     /locus_tag="IVV98_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP7806837.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            22336..22842
                     /locus_tag="IVV98_001166"
     CDS             22336..22842
                     /locus_tag="IVV98_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP7806838.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            22859..23758
                     /locus_tag="IVV98_001167"
     CDS             22859..23758
                     /locus_tag="IVV98_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP7806839.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            23845..24729
                     /locus_tag="IVV98_001168"
     CDS             23845..24729
                     /locus_tag="IVV98_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP7806840.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(24921..24992)
                     /locus_tag="IVV98_001169"
     tRNA            complement(24921..24992)
                     /locus_tag="IVV98_001169"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24957..24959),aa:Arg,seq:ccg)
     gene            25052..26386
                     /gene="rpoN"
                     /locus_tag="IVV98_001170"
     CDS             25052..26386
                     /gene="rpoN"
                     /locus_tag="IVV98_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP7806841.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            26589..27626
                     /locus_tag="IVV98_001171"
     CDS             26589..27626
                     /locus_tag="IVV98_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP7806842.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            27667..28668
                     /gene="gap"
                     /locus_tag="IVV98_001172"
     CDS             27667..28668
                     /gene="gap"
                     /locus_tag="IVV98_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP7806843.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            28778..29968
                     /locus_tag="IVV98_001173"
     CDS             28778..29968
                     /locus_tag="IVV98_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP7806844.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            30072..30827
                     /locus_tag="IVV98_001174"
     CDS             30072..30827
                     /locus_tag="IVV98_001174"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP7806845.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            30943..32241
                     /gene="eno"
                     /locus_tag="IVV98_001175"
     CDS             30943..32241
                     /gene="eno"
                     /locus_tag="IVV98_001175"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP7806846.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            32640..33779
                     /locus_tag="IVV98_001176"
     CDS             32640..33779
                     /locus_tag="IVV98_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP7806847.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        11178 a         5973 c         7207 g         9465 t
ORIGIN      
        1 agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt taatggaccg
       61 ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca cggaaatcat
      121 caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga gtgatataca
      181 tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc ttaaagaaaa
      241 gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat tcactatttt
      301 tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag ataaatcgca
      361 gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata cccggtcaaa
      421 agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct tgtatatcga
      481 tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac ttgttttgat
      541 gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat ctgtcatcga
      601 tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca aagtgatgga
      661 tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata ttttgtggat
      721 tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg cagcacgcta
      781 taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat tgttttcttt
      841 tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta aaaatctatc
      901 cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc ttcaattcaa
      961 atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc gtaaattgct
     1021 ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct atgagttgaa
     1081 aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg aagaggaaca
     1141 aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc aaaaacatat
     1201 gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg tgctgtttca
     1261 tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag accaatctta
     1321 tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg caaaagatct
     1381 gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg ggccattttc
     1441 gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca cagagcctca
     1501 tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt ggttcagtga
     1561 aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta atgggcacac
     1621 gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag tatttgtcat
     1681 tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt attcactatt
     1741 atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta ttgaacaaca
     1801 atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc aactaccacg
     1861 caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta cccagctcaa
     1921 aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat tgttccatag
     1981 actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac ggtgttcttc
     2041 tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg ttttttgaaa
     2101 ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat aaacggtgtt
     2161 caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa gccattttca
     2221 caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc agaaagtcta
     2281 ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta cacggtgggt
     2341 aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc tttgaaccgc
     2401 ttcaatgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa gatctttgac
     2461 tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc ttaacaaact
     2521 gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct gttgttcatg
     2581 ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt ccaaaacgac
     2641 attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt tcaatgcttc
     2701 caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta gctttggatg
     2761 aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa taagtttgtc
     2821 gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa taagaggcaa
     2881 tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca cttgatttcc
     2941 ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga ttggtttcat
     3001 ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt aaactatgta
     3061 agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga gaaatttcgt
     3121 gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa aagtaagcag
     3181 aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg agaaggacat
     3241 tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt tcaatgaaaa
     3301 aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt agaagctttg
     3361 gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact gcggcagcag
     3421 ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac aaactatcga
     3481 caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga attagaaaaa
     3541 gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa agatcaatat
     3601 caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga aacttatggc
     3661 cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg agaggatttt
     3721 acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa atagaacaaa
     3781 caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag aagcaaaatt
     3841 aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca tacaacacca
     3901 cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct tacaagattt
     3961 ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc ttgatttaaa
     4021 agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg aagaatggct
     4081 tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga cgaccatttt
     4141 tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac tgagtaagct
     4201 tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc tttcgtatgt
     4261 tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg ggttcaataa
     4321 agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca agcagcaatt
     4381 atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt gcagtggcta
     4441 tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac gagaaaaaat
     4501 aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg tagatgcaga
     4561 agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag atatatacgt
     4621 cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta aattgaaaaa
     4681 ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc caaaatatga
     4741 agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg ggatgatggt
     4801 cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc aaaaactact
     4861 tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct cgataccatc
     4921 gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa aagaactgtt
     4981 tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata cgattttgat
     5041 tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg cagcaaagga
     5101 aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct ggcaagggat
     5161 cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata cagcatttgt
     5221 ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg ttccgattat
     5281 ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt acggactgac
     5341 cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta tttcaggcgg
     5401 aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg ctcgattcag
     5461 tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga cactgctaag
     5521 tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt tttatacagg
     5581 aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca tcaatcacaa
     5641 gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact taattagtca
     5701 aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt tttcagggat
     5761 cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga caacaagtca
     5821 acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggtacgc aaggtttgta
     5881 tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt cagttgtaca
     5941 aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt tttcaggtat
     6001 tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac ctgaacatgc
     6061 tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag gtttcgttat
     6121 ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat gaacgccatt
     6181 gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc gttagaacaa
     6241 gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt tgaaacagaa
     6301 catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg tcagctaagg
     6361 aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga atttttaaga
     6421 cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga acaaatccag
     6481 tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt cattgctgga
     6541 gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa tgaacttccc
     6601 tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct gataaacgat
     6661 caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca aggaacgatg
     6721 agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg gaataccacg
     6781 aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag acatttgaac
     6841 ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc acgatttaca
     6901 gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta aaggagcaga
     6961 gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt tggatctata
     7021 cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg acaaatcaaa
     7081 atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg aaggatgcca
     7141 ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata cgagaagtac
     7201 gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat gatcgacagt
     7261 ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg ctgacagaag
     7321 tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata ttgcagaaaa
     7381 gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa aaagaagtat
     7441 ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta gagacagatt
     7501 atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta aagcttgaac
     7561 agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag gctttcggac
     7621 cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac cttcgtttac
     7681 tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg gtgagacaag
     7741 tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc attcaaattg
     7801 tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc aattgaagaa
     7861 atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc attgagccca
     7921 gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat tcccaatcat
     7981 caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa agcagtaggt
     8041 caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa aatcataaaa
     8101 gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca agacatgtgt
     8161 ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga tgtggcgtct
     8221 attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg ctctactggt
     8281 gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga cggaatccaa
     8341 cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg cggagttcaa
     8401 ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga agccggagaa
     8461 acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat aaaacataaa
     8521 atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg ttcattcact
     8581 attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt gacgatgctt
     8641 caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc ggatgcaccc
     8701 atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg aggagcagca
     8761 gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat tgcaaaatgg
     8821 gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga gatgacggat
     8881 gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt gatggaacgt
     8941 acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc ttctatctat
     9001 acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc tatcatggca
     9061 gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt ggaagaaatg
     9121 cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata ctatgaacga
     9181 tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac cgcaatcagt
     9241 gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac attgcgggtc
     9301 gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt tccttcgatc
     9361 gattggatac aaagctattc tctttattca acagaagtag ggaagtatat ggatcatatc
     9421 cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca ggaagaacag
     9481 cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa tgaccgtctg
     9541 acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc ttttgatgat
     9601 gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat cttgaccttt
     9661 ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat catggacggt
     9721 accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac agaattagaa
     9781 aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt ttcagaagga
     9841 ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc cattgatggc
     9901 ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta tgcaaaatgg
     9961 cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg tccaaatatt
    10021 cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag gccatccttt
    10081 agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg gacgaccgaa
    10141 agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag aagtaatcaa
    10201 tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg caatcgatca
    10261 tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg gtcttcctca
    10321 taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat cagatgattt
    10381 cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt tcatggaaga
    10441 ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag caaacgaccc
    10501 tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat atcttgctta
    10561 tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg cagaggcatt
    10621 gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc ctgggtatct
    10681 ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac taaaaggatc
    10741 ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc caatccctga
    10801 cttgactggt tatattacag aaggacagat catcttgact agagagcttt acaagagtgg
    10861 gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata agggaactgg
    10921 acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg cagcctatgc
    10981 acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt tatctgatgt
    11041 agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca atcaaggatt
    11101 ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc tatcgatgtt
    11161 gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc tgccagaagg
    11221 gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat tgactcgatt
    11281 gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata agcaagatga
    11341 actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc aagaaatgga
    11401 agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga tcacggaacc
    11461 tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta tcgtagacaa
    11521 aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac agctgacaga
    11581 cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt caatcgatcg
    11641 gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa cttgtcaact
    11701 gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat atatgacgat
    11761 ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa acgagcgcgc
    11821 agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag tggtatcttt
    11881 ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg tttgccggct
    11941 gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg cctacttacc
    12001 ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct tttcactgca
    12061 acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca ttggaacagt
    12121 gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt tatgatggtt
    12181 ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg tattatatta
    12241 aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct ttacatccta
    12301 aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt atttgtgcct
    12361 gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc tagtttttgt
    12421 aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa tgtttatttg
    12481 atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt atggcgtgat
    12541 ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc attaaccgtt
    12601 acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg caatggggca
    12661 acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat gagtgtgaca
    12721 cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc aggtctgatt
    12781 ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg cggattgaaa
    12841 acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg acgtacgaga
    12901 gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact tactttattt
    12961 tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac tgaaacgata
    13021 cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt tggtacagta
    13081 ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat cattatagcg
    13141 cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat gacaaaagca
    13201 caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg ataatttcat
    13261 cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt ttcttgcttc
    13321 ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg ttgttgaacc
    13381 tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct ttatttatca
    13441 ataggttata attcatattt ttttattttt tcttttacga tacttagtcc agaagctaaa
    13501 atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg cgtacgtgta
    13561 gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt ctcaattatc
    13621 ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg attcgttggt
    13681 ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag acttaattta
    13741 gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac ttccacatct
    13801 aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct ttggacatgt
    13861 actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt cattccagct
    13921 aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt atgttgatag
    13981 taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc tttttcaatc
    14041 acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg attattacaa
    14101 gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat caatatatca
    14161 ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata taactgagcc
    14221 aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc tggagagaaa
    14281 agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga tagagattct
    14341 aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa ttgaaaattt
    14401 gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt actagttgat
    14461 tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag accaaaatca
    14521 atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac attgggagaa
    14581 ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc atatttataa
    14641 gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct ttgggagggt
    14701 aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg ttgaatcaac
    14761 gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa cgggtaattg
    14821 tcataagaat taataggcat tttctccact ccttaaaatt gtataccata caattttacc
    14881 attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc tatgaaaatt
    14941 attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca agtaatgaaa
    15001 aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt ggtggaaatt
    15061 ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt gggggagaac
    15121 agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta tcatttacct
    15181 tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa agcattgata
    15241 aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc aacagattac
    15301 ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca agcattgtcg
    15361 catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta cgatatttta
    15421 gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa aataacgttt
    15481 ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg tacgttgacc
    15541 tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca tatcaatgct
    15601 gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga aacttctcaa
    15661 atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct tatagccatg
    15721 gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt agtttctgag
    15781 aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt tggtctagct
    15841 attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg ggctttaaaa
    15901 tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa ggaaatccag
    15961 cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa attgccattg
    16021 aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt gagcttagat
    16081 ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca acagcatttg
    16141 ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact caaagcggta
    16201 atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt attatgccga
    16261 aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt aaagaagcct
    16321 acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct aaattgcagc
    16381 cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg acagcagaaa
    16441 gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc aatgaagatc
    16501 cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga atgaataaaa
    16561 caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt gaattaaaag
    16621 aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc tcgtttattt
    16681 gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta tagctacaat
    16741 ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt ctcattttaa
    16801 ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa ctatcctcgg
    16861 atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg cgcagtgcca
    16921 ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc gtgtaatttt
    16981 tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc atacgcacca
    17041 tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt caaataaaca
    17101 agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc aaatgccttt
    17161 tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg agccattttc
    17221 atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta aggaaatagt
    17281 tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat aaaactgtta
    17341 aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt tgctgattat
    17401 caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc agtaatcgag
    17461 gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga gacgaaagaa
    17521 gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat ttcttcttat
    17581 ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta ttataatcca
    17641 ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga aaagaccaat
    17701 aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg tagccaccga
    17761 tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag tagatcagct
    17821 ttctctcagt ttttttattt attacagtac atattttttg attgcttcag ctacaccgtg
    17881 ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa cggcatttcc
    17941 cattgctact cctagaccag catattcaat catggataag tcgttctcgt tatctccgat
    18001 agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa ctgccgcacc
    18061 tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga ccgttgtgta
    18121 tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt ctggttcgtc
    18181 gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg ttcgatattt
    18241 tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat ctcgattagg
    18301 cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc gtgccatcac
    18361 ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt tacctgattt
    18421 cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt gaaaaaggtt
    18481 caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata aaacgatcga
    18541 aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta cttctctttt
    18601 ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca taatttcctc
    18661 caatatattt taatttattt caatcaatgc gccattacgg atatggctgg caaattcttg
    18721 ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca tttcttttgg
    18781 aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa gctgactaac
    18841 ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg tgcgatgtct
    18901 gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca cagcagtgta
    18961 ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga ctaattttga
    19021 atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa aacgtttagc
    19081 taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag tgcccaagac
    19141 cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa atggcagaag
    19201 taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt gtgcgcgatg
    19261 aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt acacttgcac
    19321 atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac tcatggaaaa
    19381 agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat caaatgttcc
    19441 atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat ctgcatcgat
    19501 ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga tcacactagc
    19561 taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt ctgtttctgg
    19621 agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat gttcaaatgt
    19681 atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag tcaccagccg
    19741 ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc gagaaaagat
    19801 atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac ggctatgttc
    19861 tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta gacgttggac
    19921 ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat agttatggac
    19981 tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg ttgtcataat
    20041 gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc cattgctcca
    20101 gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca gaatacagct
    20161 tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt tggtcaagca
    20221 gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt gtaccaaagt
    20281 cttcttttaa agcagattga taaaatcgct tcatgacttg cccgcgtttt tcctgattac
    20341 cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc tgagcgatac
    20401 cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa gaatgggtga
    20461 tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg agcatttgct
    20521 cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc aaagaaatat
    20581 tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc actggagcgt
    20641 aacctgcatc tttcagtgtt tggatcccgt cacttagaaa aggagttcga acatccttca
    20701 tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc tggtgttctt
    20761 tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt ttttgataaa
    20821 tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat aaattcatat
    20881 tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt tttctgtaaa
    20941 aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta tgagaagtaa
    21001 aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat tgcgtacaaa
    21061 agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc aaatggtgac
    21121 aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg gcgatgagat
    21181 tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg caggagaaat
    21241 gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc gaacaccata
    21301 cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga aagaccgtcc
    21361 cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa aaatcggcga
    21421 atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga ttttttgtgt
    21481 ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg aaattagtgt
    21541 atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg cgatcttaga
    21601 acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa actatcttgg
    21661 gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact tgaatattga
    21721 cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt atgctatcga
    21781 ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata ctccacgtcg
    21841 ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga tcgattacaa
    21901 tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc tgtttgatga
    21961 cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag aaatcggagc
    22021 agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag atttaagtat
    22081 catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg actctgaaaa
    22141 agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct atcagaataa
    22201 ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc ccaagtaaat
    22261 acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat taagtgaggc
    22321 agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat cgaaaaatac
    22381 cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg tatcacgatg
    22441 aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt tcataaagcc
    22501 ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt ttatcggata
    22561 ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt ggacttattt
    22621 gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga gctccatatg
    22681 attttagata aaatagacag tccggaaaaa gagattctga tcctctactt ttttgaagga
    22741 tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt taaaacgaaa
    22801 atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga agagtgccat
    22861 gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac aagcaattcc
    22921 caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat catttataaa
    22981 agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta tcgtaatgat
    23041 tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag atttacccat
    23101 cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat ctgaaaaaat
    23161 cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa caattcatgg
    23221 attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg aaaaagaata
    23281 tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa tcgtagacga
    23341 taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata gccatgttga
    23401 aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc cacttttatt
    23461 caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga tggccgaaca
    23521 agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag aagggacgat
    23581 agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag agcatcaatt
    23641 agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac cagaatttgt
    23701 cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg atcattagac
    23761 gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa taataagaag
    23821 agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag tattattgct
    23881 ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac cgaagtaaaa
    23941 ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga acaatcaacc
    24001 attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga atcagcggaa
    24061 aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag ccgagatccg
    24121 gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac aacaccgcag
    24181 cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt aggagaaaat
    24241 acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga gattggcaat
    24301 cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac ggaggaagtg
    24361 acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt tgttcgtccg
    24421 ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat catcgaatgg
    24481 tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca gaagatccaa
    24541 gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga aacgattcgt
    24601 gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac gacagttggg
    24661 gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga tcatcggcca
    24721 gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt agttgaacac
    24781 ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa aaaactgtcc
    24841 accaattttc tttggcggac agttttcact taaaaataaa gaagcaacta ttcgtaaatt
    24901 atgctaaaat agcagtagaa cgcgtcctga gggaatcgaa cccccgtctc aagaaccgga
    24961 atcttacgtg atatccacta cactaaggac gcaagcactg ggataattgt aactaaacag
    25021 ataaaaaatt acaaggggat tggacaaaaa aatgaaattt gagcaaaatt tttcacaaaa
    25081 acagcagcag acacagaaac tagccatgac gcaacagttg caacagtcca tccaagtttt
    25141 acaatataac agtgaggagc tgttggcatt cgttgagaat caagcaatgg aaaatccatt
    25201 ggtggaagtt gttgagccgg aatggcagcc agattacata aaagcttctt catcttctta
    25261 tgaaggagaa gagacaaatt acctaaatca gattcctgat acaaaagggt ctttatttga
    25321 ttcattgatc gaacaagtcc atttgaatta ccgagatact tttttgagga aaatcgttct
    25381 ttatcttgta gaatacatcg atttgaacgg atttttgacg attagtttag aagaagccgg
    25441 aaaagagatt ggagctacgc ctatccaaat gctcgatgcg ttgactctga ttcagcaatt
    25501 agaaccagct ggagtaggtg cacgtagttt gcaagaatgt ctcatgcttc aaacagaacg
    25561 agatgattat gcgccggaat tagcttatat cgtgttggaa gaatgttttg aggaactggt
    25621 ggagcgaaaa tggaaagaaa tcgcacaacg tttttctgtt gatctacatg ctgttcagca
    25681 gatattcgac tatttacaaa cgttgagtcc aagccctggc cggattttcg accgtagcag
    25741 cgaattgtac attattcctg atgtccgggt attagtggac gacgataaaa atgtacaagt
    25801 tatctcaaac cgaaaaaatc agccaaatat acgctttcaa gagagttact tcaaacaaat
    25861 gtcacaacaa gcagataaag aaactgaaaa ttatttaaaa gaacggaaac aggaattcga
    25921 atggttgaag aaaacgatcc tacaacgtgg ggatacaatt ttgcgggttg ctcaagtcat
    25981 tgtttcccgg caaaaagctt tctttatcga caaggaacgt ccaatcaagc ctcttacgtt
    26041 aaaggaagtt gcaactgaga tagatgtgca tgaatccacg gtcagtcgtg cagtcaacgg
    26101 gaaatatttg gaaacagact tcggtgtatt tgaattaaaa aaatttttca ctacacgaat
    26161 tcctacgaat agtacagaac agacagaaga cctttcagca gatacagcga agaaaaagct
    26221 gcaggaatta gtcgatcaag aagacaaaaa caagccgttg tctgaccaga aattggttga
    26281 attgctgaaa aaagatgaga tagcgatctc aagacgaaca gtagcaaaat atcgtgattt
    26341 attaggaatc ccgagttcat caaaaagaaa acgttatgat aactaatcag tcaaaagact
    26401 agaaaaagta tttcactttt tctagtcttt ttagttgaaa aacgagagca aaactgttag
    26461 acttacagtc gtgaggttga gatttccctt tattgatgtg aaattcgaat agttaatttc
    26521 tttttttatc gtatatgggt cgttttaagt ctacattgga cgtaaagtgt ccaactaagg
    26581 agatcgctat gctggatgaa ataaaaatga ttgaatctgt tgcaccagat attatcgaag
    26641 tgttgcaaga acgctataaa attttacgaa atatctattg gatgcagccg attggacgtc
    26701 gaagtttatc ggaaagtatg gggatcacag aacgagtatt gcgaacagaa acagatcttt
    26761 tgaaaaatct gaatttgatc gacacctcaa aaagcggtat gacgctgaca actaagggcg
    26821 aagaagttta tcaaagcctt gaaaacttca tggatcagct tttaggtacg catcaaaccg
    26881 aacaacagtt ggcagaatat tttggtaacc aacgctgtat cgttgtttca ggaaacagcg
    26941 aagagcagac caaagtggct gatgcattcg gcgaagcgct gagcgaagcc ctagaccgac
    27001 tacttccaga aggcgagaat atcatcgctg tgatgggagg aactactatg gctgtggtag
    27061 ccgaacaatt gtctaatctg gaaaataaga aacggcataa cctgtttgtc cctgcaagag
    27121 gcgggattgg tgaagcgata actgtacagg caaattctgt cagtgcaaga atggctgcta
    27181 aagcaaacgg taaccaccgt gcactttatg ttccggaaca attaagtctg gcaacttaca
    27241 attctttact caatgagcca tctatccaag aagtcttaaa cttgattagt gaagcgaatt
    27301 gtgttattca tagtattggg cgtgcattac acatggcagc acgtcgtaag atgactgaaa
    27361 aagaattagt catgctgaaa caagcaaatg ctgttgcgga atcttttggc tactttttca
    27421 atgaaaaagg tgaagtcgtt tataaggtcc ctagaatcgg catagaattg caagatttgg
    27481 aaaaagtccc gatcatcatg gcaatcgcgg gcggaaaatc aaaagctaaa gcaattcgag
    27541 cttatatgaa aaatgcacca aaacaaacgt ggctcatcac tgatgaagct gctgcaaatg
    27601 agattttaaa aggggtaacc ctttaaaata aatatttttt tgattttcat aaggaggaaa
    27661 tcttaaatga cagttaaagt aggtattaat ggttttggac gtattggacg tctagcattc
    27721 cgtcgtatcc aagatgtaga tggaatcgaa gtagtagcaa tcaacgactt gacagatgct
    27781 aaaatgttgg cacacttgtt aaaatacgac acaactcaag gacgtttcaa cggaacagtt
    27841 gaagttcatg aaggttcatt caacgtaaac ggaaaagaag ttaaagtatt agctaaccgc
    27901 aacccagaag aattaccatg gggcgaacta ggcgtagata tcgttctaga atgtactggt
    27961 ttcttcactt ctaaatcagc agctgaaaaa catttaacag ctggtgctaa acgcgttgtt
    28021 atctctgctc ctggcggaaa cgatgttcca acaatcgttt ataacacaaa ccacgaaaca
    28081 ttaactggta aagaaacagt tatctcaggt gcttcatgta ctactaactg tttagctcct
    28141 atggctaaaa cattgaacga caaatttggt gttgttgaag gattaatgac aactatccac
    28201 gcttacacag gtgaccaaat gactctagac ggacctcatc ctaaaggtga cttccgccgt
    28261 gcacgcgctg ctgctgcaaa catcgttcct aactcaacag gtgctgctaa agctatcggt
    28321 ttagtaattc ctgaattgaa cggtaaatta gacggagctg ctcaacgtgt tcctgtacca
    28381 acaggttcat taacagaatt agtaacagtt cttgaaaaag aagtaactgt tgacgaaatc
    28441 aatgcagcaa tgaaagaagc ttcaaacgaa tcttacggat acaacacaga cgaaatcgtt
    28501 tcttcagata tcgttggtat gacttacggt tcattatttg atgctacaca aactaaagta
    28561 atgacagttg gcgacaaaca attagttaaa actgttgctt ggtacgacaa cgaaatgtca
    28621 tacactgcac aattagtacg tactttagaa tacttcgcta acttataaga tagacaaacg
    28681 tacaagtgta aattatagac atgtacattt aaaagcgggg aagcaatcgc gcttcttccg
    28741 ctttttttga taataagttt attcaggagg aaataaaatg gctaagaaaa cagtgaaaga
    28801 tatcgattta aaagacaaaa aagttcttgt ccgtgttgac ttcaacgttc ctttgaaaga
    28861 cggcgtgatc actgacgaca ctcgtatcaa agcagcattg ccaacaatca actacgttct
    28921 agaacaaggc ggaaaagcaa tccttttctc tcaccttgga cgtgtaaaaa cagaagaaga
    28981 taaagaagga aaatctttag ctccagttgc aaaacgtcta ggcgaattat taggtaaaga
    29041 agtaacattc gtacctgaaa ctcgcggaga acaattagaa gaagcaatcc gcaacatgaa
    29101 tgacggcgac gttgtcgtat tcgaaaatac acgatttgaa gatattgacg gtaaaaaaga
    29161 aagcaaaaat gatacagaac taggtaaata ctgggcttca ttaggcgatg tatttgttaa
    29221 cgatgctttc ggtacagctc accgtgcaca tgcttctaac gtaggtatcg cttcaactgg
    29281 tatcccaaca gttgctggat tcttgatgga aaaagaaatc aagttcatcg gtgaagcagt
    29341 agaagaacca aaacgaccaa tgattgcaat ccttggtggc gcaaaagttt ctgataaaat
    29401 cggcgtaatc gaaaacttga ttcctaaagc agataaaatc ttgatcggtg gcggaatgac
    29461 ttacacattc tacgaagcaa aaggaatcaa gatcggtaac tctctagtag aagctgataa
    29521 agtggaacta gcaaaagaat taatcgaaaa agcaggcgac aaacttgtct tgccaatcga
    29581 caatgtctgt gcaccagaat tttcaaatga tgttgaaaca caagtaatcg aaggagacat
    29641 tcctgatggt ttgatggctt tagacatcgg cccagcatca gtaaaattat ttgctgatac
    29701 attacaaggt gcaaaaacag ttgtttggaa cggacctatg ggtgtatttg aaatgagtaa
    29761 ctttgctaaa ggtacaatcg gtgtttgtga agcaatcgct aacttagaag gcgcaacaac
    29821 aatcatcggt ggcggagact cagccgcagc agcagaacaa ttaggatttg ctgacaaatt
    29881 cacacacatc tcaacaggtg gcggcgcaag cttggaattg cttgaaggta aagaattacc
    29941 aggactagca gcaatcaacg ataaataaac gaccaagttt gctcaattct gacgagtaat
    30001 cgaacaaaag gtgaagggag ttttcatgac tccctagcca tttttcaata aattaaggag
    30061 tgtgttcctc aatgcgtaaa cctattatcg caggtaactg gaaaatgaac aaaactgcat
    30121 cagaagcaaa agaatttgct gaagcagtaa aaaacaaaat cccttcaaat gacaaagttg
    30181 attcagtcat cggatctcct gcattattct tacaagaatt aatgacatca gctgaaggta
    30241 cagaactaaa aatctcagca caaaactgct actgggaaaa ctcaggtgcg ttcactggtg
    30301 aaacttcacc agcagctctt gctgatctag gtgttcatta tgtgatcatc ggacattcag
    30361 aacgtcgtga atatttccat gaaacagacg aagacatcaa taaaaaagcg aaagctatct
    30421 ttgcaaatgg tatgacacca atcctatgct gtggcgaatc tttagaaacc tatgaagcag
    30481 gcaaaactgc tgaatggatc gaaggacaaa ttacagctgg tttagctgat ctttcagctg
    30541 aacaggtgtc aaacatggtt attgcttatg aaccaatctg ggcaatcggt actggtaaat
    30601 cagctgacgc acaaatcgct gacgaaattt gtggagttgt acgtcaaaca gttgaaaaac
    30661 tttatggaaa agaagtatca gaagcagttc gtatccaata cggcggttct gtaaaaccag
    30721 aaaatattgc tgaatacatg gcaaaagaaa atgttgacgg tgctttagtc ggtggcgcaa
    30781 gcttgcaagc agattcattc ttgtcattgt tagacgctgt aaaataattg ttgaaaattt
    30841 gcgaaaaatg caagaaatgt ttgcactaat gagcaaaatt aactaaaatc gtatatgagg
    30901 gaaatccctt aggaaaaaac aaactcaaag gagagacaaa acatgtcaat tattactgat
    30961 gtttacgctc gcgagatctt agactcacgt ggtaacccaa caatcgaagt agaagtatac
    31021 acagaaagcg gagcttttgg ccgcggaatg gttccttcag gtgcttcaac tggtgaatac
    31081 gaagcagttg aattacgtga cggagacaaa gctcgttatg gcggtaaagg tgtaactaaa
    31141 gctgtcgaca acgtaaacaa catcattgct gaagcaatca ttggctacga tgttcgtgac
    31201 caaatggcta tcgacaaagc tatgatcgct ttagacggaa ctcctaacaa aggtaaatta
    31261 ggtgcgaacg ctattttagg tgtttctatc gctgttgcac gtgcagctgc tgactaccta
    31321 gaagtacctt tataccacta cctaggcgga ttcaacacaa aagtattgcc aacaccaatg
    31381 atgaacatca tcaacggcgg atcacatgct gataactcaa tcgacttcca agaattcatg
    31441 atcatgcctg ttggcgctcc aacattcaaa gaagctctac gtatgggtgc tgaagtattc
    31501 cacgcattag cttcaatctt gaaagctcgc ggattagcaa cttctgttgg tgacgaaggt
    31561 ggatttgctc caaaccttgg ttcaaacgaa gaaggttttg aagtaatcat cgaagcaatc
    31621 gaaaaagctg gctatgtacc tggtaaagac gttgttcttg ctatggatgc tgcttcttca
    31681 gaattctacg acaaagaaaa aggtgtttac gtactagctg attcaggcga aggcgaaaaa
    31741 acaactgacg aaatgatcaa attctacgaa gaattagttt ctaaatatcc aatcatctca
    31801 atcgaagacg gattagacga aaacgactgg gacggattca agaaattaac tgacgtatta
    31861 ggcgacaaag ttcaattagt tggtgacgac ttgttcgtaa caaacactca aaaattatct
    31921 gaaggtatcg aaaaaggaat tgctaactca atccttatca aagtgaacca aatcggtaca
    31981 ttaacagaaa ctttcgaagc tatcgaaatg gctaaagaag ctggctacac agcagttgta
    32041 tctcaccgtt ctggtgaaac agaagattca acaatctctg atatcgctgt tgcaacaaac
    32101 gctggccaaa tcaaaactgg ttctctatca cgtactgacc gtattgctaa atacaaccaa
    32161 ttactacgta tcgaagacca acttggtgaa gttgcagaat acaaaggttt gaaatctttc
    32221 tacaacttaa aaaacaaata attcttttct aatgaagata catgatcgac tattgaaaga
    32281 tagtcgagta tgatcactta gttaagtaat cgaactctct acttgctgaa atatcagcag
    32341 gtagagagtt tttttgcaac tagcttctgt atatgatgtt tacaaagaat ggtacaagaa
    32401 aagatcatcc ttgaaaaagg aaagctaaca ataactagca tcatataaga gcttttaagg
    32461 atagaacagt agaataggaa tctatgagca agtcctctcg tataaataaa ataggaggga
    32521 agtagcagca tatttttcat aaagtggctc tctttcttca tttttacttt ggttgctcct
    32581 atttgaaaat tcgagcacac tcaaatacaa taaaaagaaa tggcaaggga gaggattaga
    32641 tgaaaaaaga agaaaaaatc gcgattttac aagagatcat ccgaattaaa tcagtgaatg
    32701 gaaacgaagg tgaagtagca gcctatttga ataagctttt ggcaaagcat gacataacag
    32761 gagagattgt ttcttacaga gatggtagag ataatttgat tgctcgttac caaaagggcc
    32821 aatcaggaaa agtgttaggc ctatctgggc atatggatgt cgtggcggct ggtgatgaat
    32881 cgtcttggac ctatgcaccc tttgcagcag aaatccatgg gaaccgtttg tacggacgtg
    32941 gtgctacaga tatgaagagt ggcttggcag caatggtgat tgccatgatc gaactgaaag
    33001 agtcaggaaa accatttaac ggaacagtca aattattagc cactgtcgga gaagaagtgg
    33061 gtgaactagg tggggaacag ctcacgaaag caggctatgt agatgactta gatgccttga
    33121 tcatcggaga gccaaccaat tacagtttga tgtatacgca catgggatca atcaactata
    33181 cagtcacctc gcacggaaaa gaagcgcata gctctatgcc agaccaaggt tataatgcaa
    33241 tcaatcacct aaatgaattc attacgaaag caaatgctga aatgaatcac ctcgctgaaa
    33301 caatcgagaa tcctgtccta ggaaaaacaa tccataatgt tacattgatc agtggcggga
    33361 atcaagtcaa cagcatccca agccatgcgc agctccaagg gaacattcga tcgattccag
    33421 aatacccaaa tgataaaatc attgcattgc tgcaatcaat cgtcaatgaa ttgaatcaag
    33481 agacagacta tcatttggaa ttgatgatcg attacaacaa aatacctgtc aaagctgatc
    33541 cagattctcc tttgattcat tgcattcagc aacaattcag ccagccatta cctttagttg
    33601 gagcggcagc aacaacggat gcagccgaat ttacgaaagc taaccattcc ttcgactttg
    33661 tcgtctttgg gcctggtgtc gttactttgc ctcatcaagt agatgagtat gttgaaatcg
    33721 ataattattt ggatatgatc gaaaaatatc aaggaattat tttatcctac ttagcgtaag
    33781 atttttttaa taaatgaaaa aacagagcca gattagcatt att
//
LOCUS       DACCVH010000024        33420 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.024, whole genome shotgun sequence.
ACCESSION   DACCVH010000024 DACCVH010000000
VERSION     DACCVH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.024"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            290..1201
                     /locus_tag="IVV98_001177"
     CDS             290..1201
                     /locus_tag="IVV98_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7806848.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            1418..1855
                     /locus_tag="IVV98_001178"
     CDS             1418..1855
                     /locus_tag="IVV98_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806849.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            1950..2834
                     /locus_tag="IVV98_001179"
     CDS             1950..2834
                     /locus_tag="IVV98_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP7806850.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            3058..6225
                     /locus_tag="IVV98_001180"
     CDS             3058..6225
                     /locus_tag="IVV98_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806851.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            6245..6790
                     /locus_tag="IVV98_001181"
     CDS             6245..6790
                     /locus_tag="IVV98_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAP7806852.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            6818..7273
                     /locus_tag="IVV98_001182"
     CDS             6818..7273
                     /locus_tag="IVV98_001182"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAP7806853.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            7270..8028
                     /locus_tag="IVV98_001183"
     CDS             7270..8028
                     /locus_tag="IVV98_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7806854.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(8114..8854)
                     /locus_tag="IVV98_001184"
     CDS             complement(8114..8854)
                     /locus_tag="IVV98_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806855.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            8915..10168
                     /locus_tag="IVV98_001185"
     CDS             8915..10168
                     /locus_tag="IVV98_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7806856.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            10490..10717
                     /locus_tag="IVV98_001186"
     CDS             10490..10717
                     /locus_tag="IVV98_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP7806857.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            10840..11166
                     /locus_tag="IVV98_001187"
     CDS             10840..11166
                     /locus_tag="IVV98_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP7806858.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            11234..11947
                     /locus_tag="IVV98_001188"
     CDS             11234..11947
                     /locus_tag="IVV98_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP7806859.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            12257..13107
                     /locus_tag="IVV98_001189"
                     /pseudo
     CDS             12257..13107
                     /locus_tag="IVV98_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            13228..15093
                     /locus_tag="IVV98_001190"
     CDS             13228..15093
                     /locus_tag="IVV98_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7806860.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            15141..16550
                     /locus_tag="IVV98_001191"
     CDS             15141..16550
                     /locus_tag="IVV98_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP7806861.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            16658..17359
                     /locus_tag="IVV98_001192"
     CDS             16658..17359
                     /locus_tag="IVV98_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7806862.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            17518..17997
                     /locus_tag="IVV98_001193"
                     /pseudo
     CDS             17518..17997
                     /locus_tag="IVV98_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            18845..19420
                     /locus_tag="IVV98_001194"
     CDS             18845..19420
                     /locus_tag="IVV98_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP7806863.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            19420..19860
                     /locus_tag="IVV98_001195"
     CDS             19420..19860
                     /locus_tag="IVV98_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP7806864.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            19876..20577
                     /locus_tag="IVV98_001196"
     CDS             19876..20577
                     /locus_tag="IVV98_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7806865.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(21065..21490)
                     /locus_tag="IVV98_001197"
     CDS             complement(21065..21490)
                     /locus_tag="IVV98_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806866.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            21864..22835
                     /locus_tag="IVV98_001198"
     CDS             21864..22835
                     /locus_tag="IVV98_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7806867.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            22867..24264
                     /locus_tag="IVV98_001199"
     CDS             22867..24264
                     /locus_tag="IVV98_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7806868.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            24423..25046
                     /locus_tag="IVV98_001200"
     CDS             24423..25046
                     /locus_tag="IVV98_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806869.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            25795..27888
                     /locus_tag="IVV98_001201"
     CDS             25795..27888
                     /locus_tag="IVV98_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7806870.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            28048..28914
                     /locus_tag="IVV98_001202"
     CDS             28048..28914
                     /locus_tag="IVV98_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7806871.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(28936..29373)
                     /gene="ndk"
                     /locus_tag="IVV98_001203"
     CDS             complement(28936..29373)
                     /gene="ndk"
                     /locus_tag="IVV98_001203"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP7806872.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            30032..32710
                     /gene="mgtA"
                     /locus_tag="IVV98_001204"
     CDS             30032..32710
                     /gene="mgtA"
                     /locus_tag="IVV98_001204"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP7806873.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            32797..>33420
                     /locus_tag="IVV98_001205"
     CDS             32797..>33420
                     /locus_tag="IVV98_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7806874.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGK"
BASE COUNT        11264 a         5564 c         7060 g         9532 t
ORIGIN      
        1 cccagcagcg gaagaagaaa aacaaaatcg ataacatttg ttctaagaat tagttacgtt
       61 aaatacggaa cgcaagatag acttgaaaaa cggtaacaaa agaagtagta tattaaggtg
      121 tgatgtgcta cttgacattt attctgctga gcgaactttc tggattgtgt agccttatat
      181 ctattcagga cgtatcgagc agattagtaa aggtgttctt gatgattttc atcttgaaca
      241 cctttgtttt tagcaattcg caaaaaacga aaagtaggag aattgataaa tgaaaaaaag
      301 atttttagca cttgccatcg tactaggcac tggcttattg tcaggctgta cgaatgccgg
      361 tgaaaaaaca gccgttagtt ataaaggcgg tacaatcagc gaacaagaag taatggatag
      421 cttgaaaaaa atgcaaggag cagattccgc tgtgcaacag ttgatcgttt atcaagtatt
      481 tgaagataaa tatggagatg acgtatcaac caaagaaatc gattctcaat atgatcaaac
      541 aaagaaacaa ttgggtgatt catttgattc acaattgaaa tctgcaggtt acacagaaca
      601 aacattcaaa gacagtatca aacaaagtct agcctttcaa gaaggtctaa agaaacatat
      661 caaattgacc gatgaagatt taaaaacggc ttgggaatct ttccatccag aagtggaagc
      721 tcaaattatc caagtagcaa gtgaagatga tgcaaaagat gtgaagaaag ctgctgataa
      781 gggagacgat ttctctaaat tagccaaaga caagtcaact gatactacga caaaagaaga
      841 tggcggaaaa gtgaaatttg attccactac tacaacggtt ccggcagaag tcaaagaagc
      901 agcctttaag ttgaaagatg gtcaagtttc tgatgtgatc acttctacca atgcttcaac
      961 ttatactacg gaatattatg tggttaaaat ggtgaaaaac caaaacaaag gcaacgacat
     1021 ggataaatac aaaaaagaat tgaaagaaat tgcaacagac acaaaattaa gtgacagtac
     1081 cttccagaat aaagtaattg gcgaagtatt gaaagacgct aatgtaaaaa tcaaagacaa
     1141 agactttgaa aatgttttga gtacattcac ttcagattct agtacagcaa gtagtaaata
     1201 agcggtataa ataaaaaata tgaactattt aaatcaataa aactgttcat ctaaatcttt
     1261 ttattagaac taaatcaaca gtagtttaat tactacttga tttagttctt tttattttaa
     1321 aaattttttt tacttagaat ccagcgaccc tagatatttt tctgtataat cttaaataaa
     1381 gaaaacaata tcaaaaaatg cacgtagaag tagataaatg gagtggtttt gcaaatttct
     1441 tttatttcta gaagttattc acgtatacgg atttgttttt ctcacaaata aaaaggcagg
     1501 aagtacaatg gatcatttgt atataaaata tattcatcaa ttttccgttt tggtgttagg
     1561 cacactaatt atagcgggga ttgtcgcatt tattattcaa ggccgtgaca tattaacagt
     1621 acatcaagag tttttcagtt atgcatttgg tattcctctg atcgctataa ggtctgataa
     1681 caaaaagtgg aagaaacgct attacattct cttgctattt ttgtgttttt atctgccacc
     1741 taagattttt actttattag gtatacaatg cctatcattt tcttttattt cctatatcat
     1801 tgttttaatt ttcctcagtt tcatagtatg gatgttttat cttgtcaaaa aataaatgaa
     1861 tgtttcatga acagtacttc atcacagcct aatttttttc tttatgctat cgttatatta
     1921 aagaaatcaa tcagaaggga aagaaagtga tgaaaaaagt tttattagtg gtaaacccca
     1981 gttcaggcgg tgaacaagca aaggaatttg agcaattagc gatagcaaaa ttggaatcgg
     2041 tgtttgatga agtggtcgtc ttgcatacaa aaaaagcagg ggatgcaaaa aactttactc
     2101 gcgaagcggc tacggaaggg tatcatagtg tgtttgtcat gggcggagat ggaacagtca
     2161 acgaaggaat cagtggaatc gctgaacaag aacatcggcc aaatttcgga tttttcccat
     2221 tgggtacggt gaatgacttg gctcgagcat tagggatacc gctagaacct gaggaagcga
     2281 tcaatcattt ttcgattgaa tcagtcaagc cattggatat tggaaaaata aatgacgact
     2341 attttatgaa tgtcgtcgca attggctcta tccctgaatc aatcaatgat gtagatgcgg
     2401 agaagaagac gaaatttgga aaactagctt atttcatgtc aggaatcaaa cagttagctt
     2461 ccacacaatc ctactcgttt cacgtagaag ttgatggaaa gaaggaagaa attgagagca
     2521 gtaccttgct gataggacta actaactcag tcggcggttt tgaaacatta cttccaaatg
     2581 caaaagtgga tgatggtaag ctccatttgg tttatttaaa agattcttct ttgatcgata
     2641 cgcttaaaac attgccagac ctattaaaag gagtagatga atctacgaaa aatctagcct
     2701 accttacttg tgagcaatta gttgtgtcat tagctgatga ggaagaattg acgacgaatg
     2761 ttgatggaga tgaaggggat aaattacctg tgacaatcaa agtattgccc tcacatttac
     2821 aggtttattg ttaaaatgga ggttgtgacc gaggagttgg cgggagaaca ccgcttgttc
     2881 gggataaggg actgtgacaa gacttttgtc acagcctttt ttttgtacaa aaaagaaatt
     2941 tacacctaat agaaaaattt ttccataaaa atacatattt taaatatgaa agtacaattg
     3001 gaaatagatt aaaacgataa aataaaattg tcaaaacgtc agagaggatg gtggagaatg
     3061 aatcaatgtg taaaaaagct gattgcgtcg attttgtttg tcttccctct cttgatggtg
     3121 acatccgttt ttgccgatgt agagaaaaca aacgaatcaa cgcaatcaga gaatcaaagt
     3181 tttgacaaga ctactttttc agaagaatcg attacttctg aaactacaga atctcaaagt
     3241 gaggcttcta ctaataaaag gcaagaagaa aataagacaa gtgagacctc agaagtagct
     3301 gaacaaacgt ctgatagcag tgaagcggca ctggcaagag ctgtttcagc ggatgggtac
     3361 agcgaagctg ccacaacaga agaactggcg cagcttctcg cagacgaatc agtaactaag
     3421 atccgactga ttcagccttt gactttagac agggaattag agatcaaacg agatatcgtt
     3481 attgattttg gtggattcgc tcacaatttc ggcacacacc atatttatat caatgagata
     3541 cctcagtcga tcgagttcca gaattttaaa ggaacagctg cacatccagg tggattgaca
     3601 ccaaatatcg atggaaatgc cattatcatt gcttatatga ccgatttttg gggaagcaga
     3661 tatcatttta cgggagaaat aaaatttacc gggacacttg atttgtatga tgggtccaaa
     3721 ttaggactga tttacgctcc tcgtgcaact gtcacattag atggtgtttc cggtgtgttg
     3781 gatgtccaac cagtgaagga aggactgaat gccgctccgg gtaaagccta tttttgtaga
     3841 agctatcaat tgaatgtgat caatggtagt caactttatg gaccgtatct agggaaattc
     3901 tacggttttc tagattcagg agatgagact ggtagtggaa aaacagcgcc aggaatccat
     3961 atcttaagcg gttcaaaggt ctctcttgat tatgatcggg cagatggcgt tagcgatgaa
     4021 ggagaggcag tcgatacgct acctggtaat gtcatgtttg aagtcagtgg ttcgggaagc
     4081 gaattttcgg taaatacaaa gatcaatatt accaatgaca acaatcgcgg aatcatccaa
     4141 atgagaggtt caggatcgaa agtcactgta tcgaatggtg ggaaaatcac catcaataca
     4201 gcaactacgg gcggatttcg cttgcaagga gattctagtc aaatccatgt atcaagtggt
     4261 ggacaaatct cggtcaaaat ggctggagat gacgatcaac ccgggaacaa tgggatgcgt
     4321 tttgtaggaa aaggcctttc tttgatcgta gaaggagccg gatcagttat cgacatcgat
     4381 aagcagagtg ggcgttccag cgcagttcgt tttgagaatg gtacgcaaaa gctgacagta
     4441 accaatggag gctcattgag ggtaagaaat acaggtgatg gcaaatctta cgtgaacaga
     4501 ctcaatcaag gaaatcaagc gatccaattt tatgacgctt ctggttttct agaaagtcca
     4561 ggttcagctg attttacagt cactggagaa aaatcaaata tcgatatacg cgcagattcc
     4621 ggagcaactg tagatacaac tggagatatt gatttaaatt ttacggcagg tgaaaaaact
     4681 tatttagtca tggtcgggaa aacaggggaa gataagaccg gcatcatcag tggggatgtg
     4741 ttgaatgtgg acttagaatc tcctacctat tttgatttcc aaaacaaacg gattggaagc
     4801 gagaccaatg gcataggcgg ctgggtattc caaggaaatg gagattcttc tttaaagatc
     4861 gcccattcag aaatcgcttt atggcgaaaa acaggcgcaa cattcgataa ctttgaaaaa
     4921 gacccggatt atttttctga tatgacagac ttatcgatca atgggaccga cttaggcaat
     4981 ttcgtatcaa gccctagtgc aggtttaaca aatgaatttg ctcagacagg tgccggaatg
     5041 aaaaattata atcgaatcag tgccaataat cagctcccga tgattgaatc cttaagagtg
     5101 ccaacgaatg cagataaaaa aatctatggg catgtcgttg ttcccgaagg tgtcgaggca
     5161 aagccaagag atgcttggac aggcgaagta gaagtgactt tacgtattac ttacgcagat
     5221 acgacgaaat catctgtaga aattactgct ctcacgcaag gacaaacaga tgaaaatgaa
     5281 ggggcaggat ataacccatg gggagaaggc gaacaaggcg gcttgttcga agttcaagta
     5341 cccaatgatg agagattaaa aacggaggat caagtgcaag ttgttgctgc taaaaaagta
     5401 agaggtggcc aagaagtgac agaactggac tctgccaaaa cgacagtcga tgtgattcct
     5461 cctgaacctg ctaatttaag taccacattg atcaatgcag cttctcgcac gatcacaggt
     5521 acaggtgaag caggagcctt ggtttcattg aaaaaaaatc aagctgtttt gtcagaaaca
     5581 actattgatg atacagggga atttgttctt tctatcccag aaaatcaact ttttgcagga
     5641 gatgtattag aaattgtatt aaacgaccaa gcaggagaag ctactgctaa gggtgtgcag
     5701 aacaagccaa gtaccaacga tgaaattggg aatcacaatc caagtgatac gccagttgtt
     5761 tatcatgatg ccccgccttt tgcacctgct acgaagatcg tagtagaagg tggtctctca
     5821 tttcttgccc cttccaaact cgattttggt cagatcaaag caactggttt gacacaagaa
     5881 gcatttggcc aaatggatat acaggaaaaa ttatggattt atgatcagcg agaaacgaaa
     5941 aatccgtgga tcttaacgat aaaattatct cagcctttca caaatgatgc aggattttct
     6001 atgcaggatg tcctatattt caagaaagga gaggagtatc aattagtgaa tgaagaagaa
     6061 ctggaaattg tcagaggaca aaattcaacg aatgtgcaag cagattattc agaatattta
     6121 aataacggtc gggcgtttaa acttgtctta accaaagaaa atcagatagc tggtaattac
     6181 tcagcagaga taacatggac attagcagat gcgccgacag aataaagatc aaggaggatg
     6241 attgatgaat cgaatatgga ataaaagtca tcgaaacaac tgctctttac ttatgatcct
     6301 tctccttgga ttcatccttt ggcagacacc tgtccatgcc tccgaattca attttgcggt
     6361 agattttgaa ttaccggcta atcagattga taagaacaaa acatatataa atgtaaggat
     6421 ggagcctggg aaaacacagg aaatccccta cacggtcttt aaccgaacag ataaatcagt
     6481 aacagttgag acattgatcc actccgctac gacgaattca aacggtgtga tcgaatatgg
     6541 agaatcaaaa agtaaatttg atgaaacatt aagttatgat atgaaaaact tagcaaaaac
     6601 agtgggagaa ataactgttc ctcctcaaag tgcggtcact gagacacttt cactgaaagc
     6661 gccagaaaaa gagctggctg gtgtggtcgc aggagggatc acgtttcaag aaaaaaaaga
     6721 gaacgtttct aacaaaagta cagttggtgt cgtcaatcag ttttctcaag tgaaagcaat
     6781 cttgatttga aatagcgaaa aagagtcttc cccagatttg aaattaaaaa aagcttatgc
     6841 ggatcaaagc gatggaagaa atgtgattaa ggcgaatctt caaaatccaa atgcttctta
     6901 tatgttcggc ttgactacat cggttgaaat ctacaaaaaa gaaacaaaag agccttacct
     6961 ttcaataaaa aaagaaaaaa tagatgtagc acccaataca aattttgatt tacttgtccc
     7021 attagaagga aaaaaattag ctccgggaca ttatcaagcg gttgtgaagg gtgcttggaa
     7081 agaaaaacgc tggaatctcc ataccgattt tgaaataact gatgatgcag cggaccaatt
     7141 gaatgaaaag gatattgatt taaaaaatca gccagaaaca tttgactggc gatggctgat
     7201 acttgttgga gtcattctta ttggcttatt tgctggatta tttattttaa aagaaagaag
     7261 gaaaaagaaa tgaaaaaaac aattgcatta agtaccgttc tagctggaag tctattatta
     7321 tgtacacaaa gtgtttttgc tgagaataag agctcagcca ctacagaagg aacgatttct
     7381 gtgaccaaac cagatgctgc aaatcctgaa gacgttgttc cagttcctcc tgttgatcca
     7441 aatgatcctg atactccttt tacacctgac gaaccaaatc agggaacatc cggattactg
     7501 acgattgacc aagctccaga tcttgatttt ggaacaatca agttaggtac agcaaaaaca
     7561 gtatatgctg cattacaaag cggaacggac agtactggag cacaaacaca agtacagaat
     7621 ttcgtacaag taacggataa aagcggaaat tatgccggtt ggaaattatc agtcaaacga
     7681 acagaattta ttggtacaac atctgatacg aataaactaa ctggttcaaa ggtgaaattc
     7741 aaaaacgccg tgattcgaaa tagcgcaact aatagcagtg gaatgccatc taccgtttct
     7801 ggaactggcg ctgaaggaat cgaaatccca gcagatcagg cagtagatct agtaactgca
     7861 ggagcaaatg aagggattgg cacatggatt tattcattag gagagaatgt ggaacaaggg
     7921 agacaatcag tggaattatt tgttcctgta tccaattatg ctgtagacaa ctacgtttca
     7981 acattcacat ggtcgttaac agatgctcct acagaagagg aagcgtaaaa tcatatcaac
     8041 gatttcaggg agtggagccg attcaaggcc cactccctga aatctgctat gcttacgtct
     8101 cagctcttat tcatcaactc gaagcagttt tttggaagtc atggaaacgt tcctttgtct
     8161 tttcaaagat ctttcgacca acgagtaagg agtcaccgtt gaaaaattct aacacataat
     8221 gagcagaatc aattttctgc aattgcgata agttgataca gtaagatttt aaaagtaaaa
     8281 agtaagcata cttttctaac tctgtcttca attgttttaa agaagtattc actaatttat
     8341 cttctgtagt tgttttgacc ataacttggt ttttcaaacc tttgatactt tcaatatata
     8401 aaatttcccg aggatacagg acgagacttc cacctttttg atcaataaag attttatcga
     8461 catttacgat ctgctgttct ttccaattga tctgttctag cacttgacga atttgttcag
     8521 ataaattcct gtcttttctg atatatccaa tcggaaggat tttccgattg atgatctcta
     8581 ctgcaaaatt cgtataagcg gtgaaaaaaa caatattact atgtgcattt tttttacgta
     8641 tttgttcggc gacatcaata cctgtgagtg attgcttcaa gtcgatatcg ataaagaaaa
     8701 catcgtgatt atcaatagtg cccaactgga tcaactgatt gatttgagag atagaagtga
     8761 gctgcacgat attctcgata tgatgattga ccaattctct gatgatccat tcgctgtgaa
     8821 actggttatc ttctatgata aaatactttt tcatatgcag gctcctatta aaaaaatatg
     8881 tgtacatttt gaaacaaaac aatggaggaa taagatggtc gcaacagtga cactttattt
     8941 gacctttact ttgattttag atttaggtat ctatttattc ttttcgaaac aactgctagt
     9001 aaaaaacagc tttggttgta tagctttgat ggtggtgaca cttttacttc ctatccctaa
     9061 agtgagcttt ccttacctag ttggcttatt attgatgttt cttttttatt ttactacgaa
     9121 aaacctgttt atcagctgtt tgatcagtaa tctttttttt gctatcactg gactcagctt
     9181 ttttctggtt tttgatctga tggattattt aggaaagaga catcttggaa cagcaagttt
     9241 ttttgcacta cttatcgcat ttattttcta tctattagta aaaagtatag acaaacagac
     9301 gagatttctc aacttgcttt ttacttatcc aactgaacac tattttggag gtatttgtat
     9361 tttattaagc tggggcgtga tttacttggt attgggaagt gttcacttcc gctcatctaa
     9421 ttatctgctt ctatctcttt tgtcgatagt catcagtttt ttttctttgt ttttttccat
     9481 tatgttgatc agtttccaag taaaagaaag acaacatcag gaatcgcttc aactgtatca
     9541 aataaatgaa gaatattacc atcatctaga ggaattcaaa catgattata aaagtctact
     9601 gttttcatta aaaattactc ttcaggaaaa taaaaaagaa acgttggaat ttttagaaat
     9661 attagaagat cattctgcag ctatttttga aaaaccgcaa atacaacagc taacaaatat
     9721 tgtatcccca gctgtcaggg gtgtcttttt aaaatttcta gaaaaagcag aatcggagaa
     9781 aatcccgatc caagtagtta ttcctgtcga agtgaaaaca atcccgattg atctggttgt
     9841 ttttattcgc tgtttatcta tttttatttc taacgcattc gatcatcgtg tagccgatca
     9901 gagtccgatt acgatcaatc tgctggaaga aaaagaggga tcacgtttta gtatagcgaa
     9961 caaggcaaat ccaacgaatt tgacgctatc ggagatggtc aaaagaggaa aaacctctaa
    10021 aaaaaatggc gggttaggtc tatacagtgc gaaaaaaatg ttggatgttt acgaaaatgc
    10081 agaactaaaa atcgaatttt caaaacagaa tcactatttt tttgtagaaa tgtatctggc
    10141 atctagaaag agcaaatcag cctactgact tactgtcaaa ggataagttt gaggaaagtc
    10201 tacacggaga tagagacaac aacacagcat attcaaaaga aacagaagcg tgatgaccgt
    10261 tgtcaccctt ctgtttcttt tgctatgtag ttaaacaaag tagttgacac ttccgctact
    10321 tagtattagt acgaaagtat acttcatgat actaagtaga taagaagtga aaagcggaac
    10381 ccacgatcgt caaaatgcta actgctttgc ttacaccaga taaagggaag agcaatatcg
    10441 cttattttag gcgtggagaa gcaagcaaat ccctacgatc acaaaaaaaa tgctgaccca
    10501 gcagttaaga gagttagaac aagatgaaag tatccatcga aaagcctata accaagtccc
    10561 gcctaaagta gagtactcgc tcaccgaaga aggaaaatca ttaagagaga ttctagtagc
    10621 gttgtctgtt tgggaagaag aacgtatcga aaaacaaaaa gcctcaaggg aagaagacac
    10681 gctactgcat acacatggtg gctacctaaa ttattgattt tctatgacat ttattttaaa
    10741 taaaagaaaa caggagtttt tttaaaagca tcatctattt tttatgtaaa aaaatggtat
    10801 gattaatcaa gtaagaagtg attggaagaa ggcaagcaaa tgaatagtat ggaaaaagtc
    10861 aaccagttta gagatgaacg taattggcga caatttcata acgaaaaaga tttggctatc
    10921 tctatttctt tggaagcatc tgaattgtta gaactttttc aatggaaaac gccggaagaa
    10981 gtaaaagaaa cacaattaga acgaatcaaa gaagaactgg cagatgtatt gatctattca
    11041 tacatgatgg cagacaacct tcacctggat ctagatgaga tcattgaaga aaaattgatc
    11101 aaaaataatt tgaaatatcc tgtagaaaaa agcgcaggtg tacgaaaaaa atacacagag
    11161 ttgtagaaat gtgtcattcg gctgttggaa agagcaaaag aaaaacagta aaatgagtct
    11221 ggagggagag aaaatgaaaa aaaaaggaaa agcaaaaaga tggctagtca atatcctctt
    11281 gttcctcttg ttattagtag gactagcttt gattttcaat gaacagatca aggattattt
    11341 tgtcagagag acaggagata aatatgctat agcgaatgta acaaaagaag atctgaaaaa
    11401 gaataacgat aaagatgtca gttttgactt tgatgcggta gaaccaatga cgacagaagg
    11461 ggtcatgagg tcgcaaatga gaggaacaga tctaccagtg attgctagta tcgcagtccc
    11521 ttcagtttca atcaatttac cggttttcaa aggcttggat aatacgtcac tactttacgg
    11581 agcaggaaca ttatctccag atcaagaaat gggaaaagga aattatgcct tagcaagcca
    11641 tcgtgcaacg aaccctgaat tgctgtttac accgctagaa aatttagaga tgggtgccaa
    11701 gatctatttg acagatttag aaaatgtgta tacatacaaa acatttttta aagaaaaagt
    11761 tgctcctaca gatacccaat tactgaatga agtcgaggga aaagaaattg tcacactaat
    11821 tacttgtggc gacatggacg ccgtcacgcg actagttgta caaggagaac tggaaagtgt
    11881 tacatcgata aaagatgcga cagatgatat gagatctgct ttcaatctag agacaaaaac
    11941 attttaggat actgggacat aagtcgttac agattaaaaa cagccaaagg atatgaatcg
    12001 ataaggaaaa accaatttgc tgaaaaaaag agaaacgcaa agaggtgcat ctctgatttg
    12061 gttgttttct agatagactt gtgttccagt ttttttattt tttatatgaa aaggcttgca
    12121 taaataaaaa ttcgatggta tgatgatttt gaataagaaa tggattgtta ctgtacggca
    12181 ggcaaaacca gaattcagct aagaaacagt aggcgaattc taggtttttt tatttttctt
    12241 gagagggcga agcaaaatga aaattgataa aattttgaat aacaatgtcg tcatttcgaa
    12301 aaatggattc ggggaagaag tcgtttgtat gggaaaagga ctagcttttc aaaaaaagat
    12361 tggggacgag atttcgccag aagcggtcca aaaagaattt gtttaagaga ttcttttgct
    12421 aaaaaccaat tccagcagct gatggctgat attccggcag aggagatcga atgggtcaaa
    12481 caagtagtcg aactggctga agataaacta aaagttgaat tttcgcctaa tatttatctg
    12541 acattgaccg atcatcttca ttatgcgatc acacgagcaa aagaaaatat ccaactgcct
    12601 aatccattat tatttgaaac aaaaaaattt tatccgaaag aatatcaagc agcgaaagag
    12661 gctcttttgt tcgtgaaaca aaagacgggt gtggaacttt ctgaggatga agccggtttt
    12721 attgcctttc attttgtgaa tagccaacaa ggaaacgaag acatgcaagt gacgatgacc
    12781 gctaccacaa tggtaagaga tatactgagt atcatcagta aattcttcgg catcgtgttc
    12841 gatgaagaat ctttgaatta tcagcgtatc attactcatc tgcagttttt tgcccagcgt
    12901 tatctcaaag gggaaggatc tgacgagcaa gatgaatttc tctacgcatt agttcaagga
    12961 aagtatccaa aagcgtttca ttgtgtcgaa cggatcaatg agtatcttcg acaaacgcaa
    13021 aaacaggaaa tggggatcgc agagcagatt tatttaacga ttcatattca aagagtagta
    13081 agtgagaaaa aaagcatcca atcataagga ttgttactgt atggcaggca aaacctggat
    13141 tgaaaaaata ggttcacgaa tgtttgtgac tgtttttttc aatctgggtt tttatttttt
    13201 aaataaaaaa gaaagaagga aaaaacaatg gataatcaag cagttggtcg tcgtgtatgg
    13261 gaagcggtag gaggacaaaa gaatgtcaaa agtttagtac attgtgctac gcggttgcga
    13321 ttcagattaa aagatgaatc tttagcagat acgcaaaagt taaaagaaga cccggacgtg
    13381 atccaagtcg tacaaagtgg cggtcagtat caagtagtga ttggcagtaa tgtagcagat
    13441 gtttatcaat cgatcgtgga tgaggaaggt cttgcagttt cggaggatgg aaaagaagag
    13501 tccaaaaata ttttgaatcg tctgatcgat attatctcta gtatatttac accttttcta
    13561 ggggcgatgg cagccgccgg ggtattgaaa ggattcttat cattggcaac ggtgatgggc
    13621 tggctgacag ctgatagcgg tacttatcaa atattgtttg ctgcagcaga tggtgtcttt
    13681 accttcttac ctgtcatgct tgcttttaca gcagctaaaa agttcaaagc caaccagttt
    13741 ttagcagtag caattgctat ggcacttgtg tatccagcta tcacagcagt tgctggtgcg
    13801 ggagaagcta tcagtttctt tgggatccca gtgattcttt caccatctgg ttatacttct
    13861 tctgtcatac caatcattct agccgtatgg gttcaaagta aattagagcc attcgtaaaa
    13921 aaagtgattc cgcaatttct gcaaatgatt ttagttccgc ttgtcgtttt agtagtgatg
    13981 gttccattaa catttcttgc tttaggacca atcgggacgg ttgccggtaa tgctttaggc
    14041 ggtctcttca actcgattta tggatttagt ccaatcgtag caggtctaat catgggaagt
    14101 ttatggcaag tattcgtgat gttcggcatg cattggggat tcgtaccgat catgtttttg
    14161 aatatcgaac aatatgggtt tgatgtattg atgccaatgc ttcttccagc catcttggca
    14221 caaggtgggg ctgctttagc tgtagcattg cgaacaaaag atacgaaact tcgagcatta
    14281 gggatttctt ctacagtgac ttcgttattt ggaatcactg aaccaactgt gtatggtgtg
    14341 acattacctt tgaagaaacc attcattgcc gcttgtattt ctggaggtat tggtggagct
    14401 attatcggat tttccggagt aaaagctttc tccagcagtt tggtcagctt attgacgatt
    14461 ccgactttca ttaatacggt ggatggtgta gagtcaaatg tgacagtagc agtaatagct
    14521 acaggaattg cttttgttct tgcattcgta ggtacattga ttttaggatt tgacgaacaa
    14581 acacaagaca atcaattaga aaacaaacat gcgaatgcag gagaaccgat tacttcagca
    14641 cggcatacct taaaaagtcc tttaacgggt aaagtactgc cattgagtga agtaccagac
    14701 caagtttttt cttctggcgt gatgggaaaa ggtatcgcta ttgatccaga agtaggagaa
    14761 ctagttgcac ctgcagacgg agagatcacg actatttttc caactggaca tgctgtaggg
    14821 atcacaacga ctgacggagc ggagattttg attcatatcg ggatggatac agtagaatta
    14881 aatgggaatg gctttgagat cttagtcaaa caaggggatc tcgtcaaagc aggagattta
    14941 ttgattcgtt ttgacatcga agcaattaga gcagctggct atagcgtaat cactccagtt
    15001 gtcattacga atactgatgc atttgccgat atacttgaat tagaccaaaa agagattatt
    15061 gcaaacgaag atgttctggc aattgtaaaa taaggaggaa atcaggatgc aatcacgttt
    15121 ttcagaaaaa tttttatggg gtggagcaac tgctgccaaa tcaattagaa ggggcttatg
    15181 atcgagacgg aaaaggacta tccgttgcag atgctatgcc tggaggtaag cagcgctttg
    15241 cgattatcgg cagtgaagaa tttgactgga cgattgatca agaaaaatat atttacccga
    15301 atcatcgagg aatcgatcat tacgatcgtt tcaaagaaga tcttgccttg tttgcggaaa
    15361 tgggattcaa atgttatcgt ttttcgattg cctggacacg aatttttcca aatggagacg
    15421 aaggtactcc taacgaagcg ggattagaat tttatgatca gctgattgat gagtgcttaa
    15481 aatatgatat tgaacctgtg atcacgattt ctcattacga aatgcctctt catttggcaa
    15541 aagaatacgg tggctggaaa aatcgaaaac tgatcgactt ctatgaacga tttgctcaga
    15601 cagtattaga gagatacagc agtaaagtca aatattggat gactttcaat gaaatcaatt
    15661 cggcctttca ctttccagct ttaagtcaag gattagtaaa aagcaatgga gcaggagagt
    15721 accaaaatat tttccaagca tggcataatc aattcgttgc aagtagcaaa gccgtaaaaa
    15781 tcggccacga attgcgttcg gatatccaaa tcggctgcat gattatctat gcaacaactt
    15841 acagcatcga tgccaatcca gtcaatcagg cagcaacaat gatccaaaac caagaattca
    15901 attttttctg cacggatgtc caagtacgtg gagaataccc tgcatacaca gcgcgtaccc
    15961 ataaaaaata tggagtcgat ccggaaaaat tagagcaaac ggaaaaagac ttccagttgc
    16021 taaaagaata tccagtggac tacatcggat ttagttatta tatgtctacg gcaatcaatg
    16081 agactgatcc acaagcagca acttcagaag ggaacttgct gggaggagta aaaaatccgt
    16141 ttcttgaggc aagtgaatgg ggctggcaga tcgatccaga agggctgaga atcgcattga
    16201 atgaattata caatcgttac cagaaaccat tattcattgt tgaaaacggt cttggagcca
    16261 ttgatcatat ggaagaggat ggcacgatta ttgatgatta tcggatcgat tatttacgtc
    16321 gtcatatcga agcgatggct aatgcagtag cagacggtgt agatttgatg ggctatacgc
    16381 cttggggatg tatcgatctt gtcagtgcat caacaggaga aatgagtaaa cgttacggct
    16441 ttatctatgt ggatctagac gatgaaggaa atgggacact gaatcgatca aagaaaaaat
    16501 cttttgattg gtataaagaa gtaattgcct caaatggcgt aaacttgtaa ttaaagcagc
    16561 tgaatgaaaa agaacacact tctcacatgt gatttgtgtt ctttttttat tttttatgtg
    16621 ctattctttt agtaatagta aagcaaaggg tgacgttatg aaaaggacac gtgtactata
    16681 cttggaagtc gcagataaaa ttaaagaaga tattttctca ggaaaatatc cagtcggttc
    16741 gatgttgccg acagaaagtg aattagaaga actgtttcaa gtcagcaaaa tcactgtccg
    16801 aaaggcaatc gaactgctgg catcagatga atatgtcgca aagaaaagtg gtcgtgggac
    16861 gacggttcta agcaatcgtc cttacaatcg attatccaaa gcggcaagct ttacgcaaat
    16921 cttggagaac tcccgatatg aagtccggaa agaaacgctg gatttgcaat tggtccatat
    16981 aaagaaggaa gatcctttgt tttccttttt cggtgagcaa gctgtttgtt ttaagcgctt
    17041 atattatttg aacaatcagc cttatattta ttttgttcat tatcttccac aagaaatgat
    17101 gcaattcagc agagaagaat ttggcaaaga atctttgtat cgtttgctga cgaaaaaagg
    17161 atatactatt gactcatttt ctgatgattt ctcggcagta tttttaacag aagaagaaca
    17221 aggaattctg aaaacagacg cacagatcgg catcaaacgg atacggaaat cgtctacgca
    17281 aattggggaa atgattgaat attcggaggc ggtctaccat acggagctgc atccttacca
    17341 tattgattat gaaacataaa taaaaaaaga ggttgtgaaa aagctgccct gcatcaagta
    17401 ataagaacag ccaaacaaaa atagcttctc atatttttcg tttggttagg cttattaccg
    17461 cagatacacg gctgtttctg gattaccatt tattctggat aagggggtgt ggcacgattt
    17521 tcagaaggaa tctatgaacc aatcactgta ttgattttag cttcgatggt aaccccattc
    17581 ggcttgacga tcgcttattt cttagggaaa atcattcgta aaaatatact caatcgtcaa
    17641 gaaatcgata cattgaagac cgcttttcct atggggatct gtcagatcac agagggatgt
    17701 ttccctatcg tattgaacga cttggcacgc aatgtcatag caacgggagt cggtgggaca
    17761 gtaggtggcg gattaagcat gttttggggc gcagatagcc gtattccggc atcgggaatg
    17821 tttgcagtcg ctacgatgac cagaccatgg gcattcattg gtgcattgtt agctggttct
    17881 tttgtcacag gaataaccat tttattattg aaaaaaccag tagatccgaa tgcagaaatc
    17941 atccaagaag aaaaagagga agaagacata tcttgggatg atttgacaat tagttaggag
    18001 aggcagaatg gattacaaga aaaaagtaca atagatgtac cttgagacag gaatggtatg
    18061 aaagaatcag agttagaaag aatcgaatat acagattttg gtttaggagc gatcgaaact
    18121 gtccagagca tcggcaccct ccttgaaatg acgatgaagg aaaaatgaga acctttcgtt
    18181 gtcgaaaggg tctggtatac cttatgtcga aggaaaggaa acaaaaaaac tttcctgtac
    18241 tattccaaaa aggaaagaaa gttattatac agtaaaaaaa gaaattattc ttcatgctag
    18301 agatcagtac acgttcgagc ccaatatcaa acactagttc caggcaggcg caacaggtgc
    18361 ggttatcact gaattttctt ccagcagtga cgattcaagt gatattttta caaatccagc
    18421 tatttatcgt taacaaaaag atttttagga gaagctgatg aacaaaaatg atcaaatttt
    18481 gatcgtttag ttcgtcggct tttttattta gagaaacatc atttatcagt gaaacataac
    18541 acgagaacaa aatgattttt tcgttaataa aagaaacaag tatttgttgt ttaaaataat
    18601 acacgttatt ggcatatagg acgaaatccc agtatcttct ataagtaagt catttcatat
    18661 cgatgaaaac acgttattta tttttgtttt atctataaaa tggctgaaaa atgatttttt
    18721 tctaaatact atatatagtg gcgtctatcc tatataccac taaaaaacta caaaatctag
    18781 tcttttattt taaaaaaaca cgtgtagaat gaagatagac ttttgagtta gggagtgttt
    18841 ttttatgaaa cttactgttt tttgcggttc ccgttttggt aataaagaaa gttacaaatt
    18901 tattgcgcaa acgttaggaa aatacatggc acaagaagaa atcgaactgg tttacggtgg
    18961 ttcatactcc gggattatgg gagtgattag taaaacagta ctggaaaata acggaaaagt
    19021 cacaggtatc tatccgaatg ggctttttga aactgaattg cctggaaaag atgttactac
    19081 atttattcct acagaaacga tcgatgaaag aaaggtatta ttatttgaaa agggagatgc
    19141 tgtcctcgtt ttccctggag gtctaggtac attggaggaa ttctcacaac ttctttcttg
    19201 gatagcaatc ggtctgacgc ccgacaagcc aatcggaata ttgaatattg gcggttatta
    19261 cagcggcttg caacaattat tagaaacttt tgcaaaagag gattttatgg ataaaaaatg
    19321 gttggatcaa gtaatctttt ccaacaatcc attggaactg gtcaatgaat tacgagcagt
    19381 atctattaaa aatcagttat tattgaagga ggcaaaataa tgagtcaaat atatttagca
    19441 ggaccatttt tttcagagga gcaaatcgat cgagtaagtc gtatcgaaaa agcgttggag
    19501 gaaaacaaaa cagtcacaag tttctactct ccacgtcatc accaagaaag caattatgaa
    19561 ctattcagcg ctggatgggc gcaggaagta tacgaaaaag atatggaaga actgacaaat
    19621 gcagaatttg ttgttgctat ccttgacttt gagcatcaaa caatcgatcc aggaacggct
    19681 tacgaattag gtgtggcaac tatgttgaaa aaaccgatga tcattgtaca agaagagacg
    19741 gtacctacga acttgatgat tacacaaagt ctccatacgt atttaaaatc agaccaagct
    19801 gtacgtgaat atgattttga aacattgcct gttgaaactt acgtaggcga gtacttatag
    19861 aagaggaagg gttgtatgtc agtgattttg atttcaggaa cgattggtgc aggtaagagc
    19921 agtttgacgg atatgcttgc aaaagagatt gattctaaac cattttatga aaatgtcgaa
    19981 gataacgaag tattgccgct cttttattca aatcctgagc agtacgcttt tttattgcaa
    20041 atcttctttt tgaacaagcg atttttagca atgaaaaatg ctttagtgaa cgatgacaat
    20101 gtgctagacc gatccatcta tgaagatagc ctgttgttcc atctaaacgc tgatttaggt
    20161 cgggtaacgg atatcgaagt acagcagtac gatagcttat tagatacgat gctaaacgag
    20221 ttagatgatg ttgctccaaa aaaacggcct gatttgatgg tccatatcaa agtttctttg
    20281 gacacgatgc tagaacgtat caaaaaacgt gggcgtgact atgaacagct agaaagcgat
    20341 gagacgttat atacctatta tgaaacgttg aacacccgct ataatcaatg gtatgaagat
    20401 tttgatgtat gtcctaaaat acaagtggat ggggataaat tcgattttgt agaaaatcca
    20461 gaagatgcaa aaaaggtgat ccgtcagatc caagaaaaat tagctgaatt ggaaggaaag
    20521 cctgctggaa aatattttac ggataaccag catgcaaaag gtcaagaatt aggctaaaaa
    20581 taaaaaacca aacgacggga aagaaaaatt actacgtgat gtagaataag cctttctatc
    20641 gtttggttat tttatattca aatatttgaa ataaataaat ctttactctt tgatttgtaa
    20701 actgaaatga tccactgttt gttttactga tgaagcttga tcaaaggaag aagctgagtt
    20761 tgaagttcat aaaaatcagc catagtgagt tttgcttgga tttgtttatc ttcttctact
    20821 ttttacataa ttttgaacag gataagattc aaatgtttta aatgaatctt tgactagttt
    20881 gtgacagttg tcgcatatgc tcaagcttcc ttggtcatta aattctgtat ggatattttt
    20941 gttgttatta catgtacaat aatcaggact atcgatcatc catttcgtct cctttacaat
    21001 catcttgctt ctttactata gcagaaaaga aggggagaaa caaaagaaga tccaacagac
    21061 ggcactatag actgtagatg ttgccatcct catccttcaa acggtaatta ccgatttttg
    21121 taaatatgac tgttgtttct tttttatttt cttttcctga aataatatat tcgtcatctt
    21181 tggtagtgat cttgatatct gtcagcactg ttttttcttc agatgattca gaagaatcag
    21241 ttccttgtgt ctgatacgtg cgtgtccatt ccattttttt atctgtaaat gtcaactgtc
    21301 ccgcggataa atccatatct ttacgtactt ttagcgtata tacactgttg gtggtatctg
    21361 ctttttccgc ttttaagaca gaagaatcgg ttgtttcgtc cgaggattgg tcagagccgc
    21421 caaacaaatc acagccagtc aatgtcaaaa gtcccgcaga caaaataaat agtacgatta
    21481 atttcttcaa aatacttccc ccatttgata ggataaagaa attataccat tggaatgtaa
    21541 aacttcaaac ggatggaaga gaaaaacgca caaaacaccc acaaatagag taaattttag
    21601 aataaaattt taaaaaggca aaaaatccgc cactttcaga aagcgtttta aaaaagtgtt
    21661 gcaatctttt aaaaaaatgc tatattaaaa atgaaccggt tcaaatactt gtttaagtat
    21721 aattaatagt gagaggaagt tgctctactg aagactttag ttatatggat attgatgaca
    21781 agcaacacta tgcaaagaat gcggtcatca taatcgaaca acaagaaaga gaaatcaaat
    21841 gtaactggca ggagtgagaa tgtatggcat cgatccgtga tgtggctaag atggctggtg
    21901 tttcagtggg aacagtttcc cgttacttga atggtcagca actgaaggaa aagaacatga
    21961 aaaaaatagc agaagcgatt tcagcgttgg actataaaga aaacatcatt gctaaagggt
    22021 tgaagaataa tcgaagcttc tctattggac ttttgataaa cgggatttcc agccgttttg
    22081 ggtcggaagt tgtctcaggg atcgaaagag tagctgaaga aaatgggtat agcttattat
    22141 taagcgggtt tgccgatcag ccagaaaaaa ttgaacaaaa aattgaatac ctgatgaagc
    22201 atgtgatcga tgggctgatt gtcttcttat ccgaagaaga gtggtctgga tttgaaatgc
    22261 tcacaaaaat gagtattcca gttatcgcat tgaattgtcc agaaggacca gcaggtattg
    22321 atacaatatt agtgaatgat cgagaaagtg tagcaaaagt gatcgctcat catggtgaac
    22381 aaggacataa aaaaatcgga tttattgctg ccactcaaac agactacgta gcaagagaac
    22441 gtttagcagg agccaaagaa gcggtccaaa atgatccatc gatccaatta gaggtcttta
    22501 caggagacta ttctagaaaa agcggctatt acggggcaaa agcattatta gaaaaagggg
    22561 caactgctat ttttgtcagc aattacaata tgtcgattgg tgccatcgaa tgtttcaatc
    22621 aagaaggtgt cagaatcggg aaggatattg cgttcagtca ctatgattat ttagataaaa
    22681 acgatctgag tatccttccg aaaatcacga tcacgccacc aacagataaa atcggggaac
    22741 gagcagcaga acagctgtta aaacgaatca aaaaagaaga ggaagaaaat gaaaaagtga
    22801 ttgtgatgga aaatatcata catggaatca actaaaacga actaaaaaag aaaaagaggt
    22861 gctttgatga aaaaatatca atttccagca aatttttggt ggggttctgc agcaagtggc
    22921 ccacaaacag aaggaaggat ttcaggcgat ggaaaaggag agaacatttt tgattattgg
    22981 tacaaaaaag aaccgcaaaa gttctttgat caagtaggac ctgaaaaaac ctcgcaagtt
    23041 tatacgaagt atcaagagga tgtacagttg atgaaacaga ctgggcataa ttcatttcga
    23101 acatctatcc aatggagccg tttgatacct gatgaatctg gaacaatcaa cgaagaagcc
    23161 gttcgtttct atcatcgtta ttttgatgag ttgattgaaa acggtatcga accctttgtg
    23221 aatctgtatc atttcgatat gccgatgtat ctgcaagaaa aaggcggatg gttgaaccga
    23281 gaaacggttg aagcctatga aaaatatgcc aaaagttgtt ttgaattgtt tggttcgaaa
    23341 gtaaaaaaat ggtttactca taatgaacca atcgttccag tcgaagcagg ttatttatat
    23401 cgatggcatt atccagaaga gtcagatatg aaaaaagcga tccaagttgg ctatcatgaa
    23461 gcgttggctt cagcgttagc catcaaatct taccatgaaa tggagcaagg tggtgttatt
    23521 ggtatcatct tgaatctgac accaagctat ccaagagacg aatcaaaccc tgaagatgtt
    23581 aaagcagcgc aaatagcaga tgcgttcttc aatcgttcat tccttgatcc agctgtaaaa
    23641 ggcgagtttc caagtgaatt gattgagata gtaaaagaac ttgatctcat gcctgtgatc
    23701 catgcagagg atttgacggt tatcaaagaa aatacagtag atcttttagg tatcaattat
    23761 taccagccac gccgggtaaa agcaaaagaa acaccaatcg atactaaaaa cggtccaatg
    23821 cctgaggatt atttcgacaa ttatgaaatg cctggtcgta aaatgaatcc ttatcgcgga
    23881 tgggagatct atgaacaagg aatctatgat attttgatca atgtacgaga tcattatgga
    23941 aatatcgact gctttatttc tgaaaacggt atgggtgtag aaaacgaagc acgatttatc
    24001 aaagaagatg gcatgatcca cgatgattat cggatcgaat ttgtccaatc tcatctgaaa
    24061 tatgtccatc aagccattca agaaggtgcc aattgtttag gctatcatat gtggacatgt
    24121 atggataact ggtcgtggac caatgcatat aagaatcgat atggctttat ttcagtagac
    24181 ttagcacaag atggaaaaag aacaatcaaa aaatcgggtc attggttcaa agacgtatca
    24241 gataaaaacg gatttgaggc ttaagaaaga atagttgaga gcaaatgcgt gaaattctcc
    24301 attcttacca ttttgtgaaa aagaagttca attatttacg atctttttca acttttttgt
    24361 ctttctattt cattttttgt atataataga atagtcaaaa ttaaatagga gtggaggaaa
    24421 gcatgaggaa aaaaagaccg tttcttctct tttggttatt cggttttttc ttactgctta
    24481 ttttatccgc agcattttca ggaaaaatga cagcagatct tgctcagaaa gaaacagaaa
    24541 aaatcgtagc aagcaaagaa tcagtagata atttcaaaaa agaattctca acttattggt
    24601 gggcggagta taaaataact gccaattacg aaaaaggcga attggacatt tatttgccaa
    24661 aaggaaaaga agaaaatcaa tttattaata tcgatgacgt acttagtgcg atttctctca
    24721 gacaatatca atttaaagac aagcatttga ccgttttgct tttgactcat gatggcgaca
    24781 aagtagcccg tttgaaaaat ggaaaagtga tcaccgctta ttctgaaaaa gtagacaaaa
    24841 aagtggtcgc cgatcgttta gcggaatgga aaaagacaaa tgaacaagtc aagaaaacaa
    24901 ctgtctcttc tcaaaaaaac gagtcgacag gaacaagtcc ttcagattct ggcagtggac
    24961 aaacgataac gggaagtgaa gaaaatcaag cctcaattat tacgaatgag tcatcacaag
    25021 gacaatatca atcctatgga caatgaaaaa cagaggttgt gaaatcagcg ttttgacctg
    25081 agtattagag aaacaaacgg caaaatagtt cctcatattt tgccgttttt tgagctaata
    25141 ccgaaggtca gctgattgaa caccgtgtat caagaggtct tgagcctgcc gtttaactct
    25201 gagccacaag gagcaatttc aaaaaatagc tccttatatt tttcgtttgg ttgggcttat
    25261 taccgcagat gcaagctttt gaacaccgtt taccaagagg ttgtaaaatt agcgtcctga
    25321 cataatctaa taccgagggt cagctgattg aacaccgtgt atcaagaggt cttgagcctg
    25381 ccgtttaact ctgagccaca aggaacaatt tcaaaaaaca gcttctcatg ttttataaat
    25441 attgtgactt gtggccgagg agttggcagg agaacaccgt ttaaggaaga agttgtgaaa
    25501 aagctgtcct gcatcaagaa ataaggagct gcgacaagaa ttttgtcaca gcctcttttt
    25561 ttgtacgaat accgagaaac tggcttttga ataccgtgga gtgaagcggt caccacaaga
    25621 cttttatctc ttcattagtt taatcgctta catcgcagcg gttttatgct gtgaaaagtg
    25681 gacggaataa tctttagaaa gaataaaaaa atcttaagat aacaactttt ttaggaaatt
    25741 ttcatttttc aggagcaaaa taagaaaaaa tgtgaataga gagaagtgat atacgtgaca
    25801 caacttaaaa aattgtgcca aaatcgttta gcaatcgttt tgacagctgt tttctttttc
    25861 tggctgaaga cgatcattgc ctactatgca gatttttcat taggtgtgga aggtacgatc
    25921 cagtacttta tcttgtggat caacccaatt gcgactacct tattgttttt tggcctttct
    25981 ttgtatatta aaaagccaaa gccagcgtta gctattcttt tgatcattga tattttaaat
    26041 acgcttttgt tgtacttgaa tattattttt tatcgggaat tcacagattt cattacagtc
    26101 aaatctgtat taggcttttc gaaagtgtcg caaggattgt caggaagctc cttttctttg
    26161 atgaagcccc atgatgtcat ctactggctg gatatcgctg tgttcattgg gctactggtt
    26221 tggttgaagg tcaagaaaat acctatcaaa agcaaccctg tcggcaaacc gatggctatc
    26281 gctgttacct gtctttcagg gcttattttt tcaggaaatc tagcgctgag cgaagccaac
    26341 cgtccacaat tgctgcagcg aacatttgac cgttcatata ttgtcaaata tctaggaatc
    26401 gatgcgtata ctatttatga cggaatcaaa acaggaatga ctagcagtgt tcgcgcgcat
    26461 gcaagcagta atgggattga tgaagtttta gattatacaa agaaacatta tgcagagcca
    26521 aatcccgaaa catttgggat cgctaaaggg aaaaatgtga tcgttctcca tttagaaagt
    26581 ttccagcagt ttttgattaa tatgaaggta gacggacaag aagtcacacc gtttttaaat
    26641 agtattttcc agaatcaagc aacgatcagc tttgacaatt tctttcatga agtaggacag
    26701 ggaaagacaa gtgatgctga aaatatgttg gaaactggca catttggttt acctcaaggc
    26761 tcattattca cagaacttgg gtcagacaat gtctttcaag ccgcaccagc gatccttgga
    26821 caaaagcaag gctatacaag cgctgttttc catgggaatg tagctagttt ttggaataga
    26881 gatcatgtat ataaaaactt aggttatgac aatttctttg atcgatctta ttttgatgaa
    26941 tccgacgaaa cgttaggtta tgggatatta gataaagatt tattcagaga atctgcccaa
    27001 tatcttgagc atctacaaca gccgttttac acgaaatttc tttccgtaac caaccacacg
    27061 ccttattata cggatgacaa gaatttcgac tttccatctt tgaatactgg caatagcaca
    27121 gtagataatt atgttcgaac ggcacattat ctggatcaat cattggaaca attttttacg
    27181 tatttgaaaa aatctggtat ttaccaaaat tcaatctttg tgatttacgg ggatcatttt
    27241 gggatctcga atacagataa taaagattta gcaagcgctc ttggtaaaga tccagataca
    27301 tgggatgaat ttgacaacgc acagatgcaa cgagtgccat tgatgatcca tatgcctggt
    27361 tatactaaag ggacagtcaa tcatgaatac ggtggagaaa tcgatgtttt gccgacatta
    27421 ctacatctat tgggaatcga tgataaagat tatcttcatt ttggtacaga cttattatct
    27481 tctcagcatg atcaagtagt tgcttttcga aatgggaact ttgtgacacc caaatacacc
    27541 gtcctaggag gaaaagctta caataatcag acaggagaaa tcatcgatac gaaagcagca
    27601 ggaatcgatg aggaaatctc caaagatcag gaaaaagtca agactgcgtt aagtctttca
    27661 gataagctga atcaggaaaa tctcttgcgg ttttatgtgc caaacggatt tgagacgatt
    27721 gatccgaaaa aatatgacta taaaaatgaa gcggaacgta atgaagcaat cgaaaagcaa
    27781 aaaggcgaac attcgacaag tgtcttttca aaaaatggta ataaaacaac aaccaactta
    27841 tatccagtaa caagaacaga cgttgaacag caaaaaaata atcaataaac aatcaaacca
    27901 accttcagta gttagacaac attctaatgc ttgaaggttg gtatttttta tgaaaaaaac
    27961 atttttttat ttttttcgtg tatttttcct ttttaacgta tctatttatt gaatgtggaa
    28021 aaatttaaat taaaaaggag aactattatg tatgatggtg aattgatcaa gaaacttcga
    28081 gtcaacaaga agttgacaca gtcccaatta gcggaaggaa tctgttttaa gacttctcta
    28141 gtcgggattg agacaaattc agtgaaaaaa atgtcatttg taacattgag atcattttta
    28201 gagcgaatga acatgacact tgcagaatat gaatggatgc gaaaccagct ggatgaacca
    28261 ataaagttaa agaaaaaaag acgaatgcta gatcgggtac aagaagacag ctttgatcct
    28321 tataaagaga tcagcaataa ccgtaggcat tttaagaaaa cagaagatct gtattatttg
    28381 gttttgaatc ttcacatggt cgaaaaaaca gaagtatctg agacagaatt tgaattttta
    28441 cgttatgaat gccgaatcat tgaagaatac ttgatgcaga taccagacta tggtcaattt
    28501 gaactatcta ttctagctga ttttccttgg atattcagtg atcggttcat tgagaacaat
    28561 tatttgaaaa tcaaaaaaag aatgcgacga ttagcacagt tgaacaatca tgagcagtat
    28621 ctctttactt ttttaatgaa cctgacttcg ttttatatag aaaatggtcg gttgaaaaag
    28681 gcacgtagtg tgaatgaaga tatgaaacgg agcttatcac ataaagaaag aagtacagtg
    28741 atctatgaaa cattgatggc agattattat caaagattga tttctgctgc tttaggggaa
    28801 gaaaagacga aagactacca agaattcttc acagtgctcg aatatatgtt aggaaagaat
    28861 caacggaggt ccttagagaa aaaactgctg gccattgctg aacccagcaa ctagaccagc
    28921 agtttagaat ttgtatcact tcgccgcttt ttcagacggt ttgtttatat cgaatggcgg
    28981 gaaaaagcgg gcgatctctt ttaccgcagc atcacgggaa tcagaagcgt gaatgatgtt
    29041 ttcagtcccc ggcagcgcgt agtctcctcg gatcgtacct ggaacagcat cggcagcttt
    29101 tgttgctcca accatcttac ggacgatatc gatcacttcc tcgccgacca gcacaagata
    29161 aacgacagga ccggaagtca tgtaatcgat cagttcatca aaaaaactgc gctcagtcaa
    29221 gtgctgataa tgttcttttg ctaattcagg agtcatagtt tcaaacttca tttcagcaat
    29281 ggccagtccc tttgcttcaa aacgttggat gatgcttccg actaaatggc gtctcacgcc
    29341 gtctggcttg ataataacaa gtgttctttc cataacagca cctcgtttcc tactatattt
    29401 ctattatagc gggaggtgga aaatgagaca aataaaaccg cgtgagacag gaatataacg
    29461 tgtgtatttt aaaaaaagta tgaaaaacat ggaaaattga tttgacatcc tcttttttag
    29521 ttgttatatt aacgaaggaa aaccgaataa gatttgttag gtgaggctcc tatacaaaca
    29581 taggctactg cccaaaaacg tcgagagacg ccaatgggta gaacaggaat tgtcgagata
    29641 aggcttttca taaggtagct aaaagcaggt atctgctttt tacgttgtac agtgtcaaaa
    29701 ctcaacgatg agatctgaga agcttttttt aatatgcttt ttcaaacctt tcgctgagta
    29761 tttggcgaga ggtttttttg ttgccgcaaa tccccatcgg tgaaaaataa aaaggaggtg
    29821 gtctaattgg aaaaataact attcgaaaaa tgattggaag tcatgaatta aaattactta
    29881 gtaaaggaga tgagaacaaa tggatgacag tcattcgaaa aacaaggatc tagaggaaag
    29941 gccagggcta ttatctatct gttctcagcc cctttcagtt ttttctctat cgatccgatg
    30001 aatagctaaa gaccaaaagc agcgagaaca gctgtctttt ggacacaaag gagagattga
    30061 gatggaaaaa aagaaagata cacaaaaaat ctatgcagct tttgctggaa aaacgaaaca
    30121 agaattattt gaactattcc atgcatcagc aaatggattg acagaagaac aaatcgaacg
    30181 ttcaagagaa aattacggtg aaaatgcgat ttcatatggc aaaaaaacac cattcattgt
    30241 agaaatattg aaagcataca tcacgccatt tacattagtg ttgatcgcat taggaattat
    30301 ttcattcatc acggaatatg tattagcagc tcctggagat aaagatcttt tcggtgtagc
    30361 cattatcttc actatggtta tcgtcagcgg gacaatgacg ttgattcagt ccgtacgttc
    30421 caatcaagcg gctgaaaaac tgaaatcact tgtgaaagta acggcagctg taaaacgtaa
    30481 tggaaagtac acagagattc ctatggaaga aatcgtctgt ggagatcttg ttcggctttc
    30541 agcaggggat atgataccag cggatatgcg tttattgtcc gcaaaggatt tattcatttc
    30601 ccaagcagca ttgacagggg aaagctatcc agtagaaaag catgcgaaag tatgtgaaga
    30661 cgatcagcaa agcgaaacaa gttacgaaaa tcttgtcttt atgggaagta atgtcatcag
    30721 tggaagtgcg gaaggaatca ttgtttctgt tggaaatgaa acactatttg gtcatgtagc
    30781 agaaacgcta tctgaaaaac caattcaatc aagctttgaa ttaggcatcc ataaaacatc
    30841 catgctactg atcaaattta tgtcattgat ggctccagca gttatcgtca tcaatgggct
    30901 tacaaaaggg gattggctag aagcttttct ttttggacta tctgtagcag ttggtctaac
    30961 acctgaaatg cttccaatga tcgttacgac gaatttggtc aaaggagcaa gtgtgatggc
    31021 caaaaaagga acagtgatca aaaatttgaa tgccatccag aactttggtg caatcgatgt
    31081 gttatgtacg gataaaacgg ggacattgac acaagataaa atcattcttg aatatcatat
    31141 ggattgtgaa ggaaatgaag atgatcgtgt tttgcgccat gcgtatctaa atagctacta
    31201 tcaaacaggg ctgaaaaatt tgttagatgt ggctatcatt gatgaagcaa cagaaacttt
    31261 agatacagat aagatcaatt atcaaaaagt ggatgaaatt ccttttgatt ttgaacgtcg
    31321 tcgtatgagt gttgtggttg ctgatccagc tggtaaaaca caaatgatca caaaaggcgc
    31381 gattgaagaa atgctgaaca tttctaaatt tattgatctt ggcggtactg ttacaccatt
    31441 aacaaaagaa cgaaaagaag ccgtacttgc aaaagtacag tcacttaatg aagatggctt
    31501 acgagtgatt ggtgtcgcac aaaagaccaa tccaagcgtc gttggagaat tttcagtcaa
    31561 agatgagtca gacatggttt tgattggtta tcttgctttc cttgatccac caaaagaaac
    31621 aacgaaacaa gcgttgaaag ctctgaaaga acatggtgta gctgtaaaag ttctgactgg
    31681 ggacaacgaa ttagttacac gttcagtgtg ccgtcaagta ggtctagaga tcaatgaatt
    31741 ggttaccggt gagaaaatct cggaaatgag tgatcatgaa ttagcacaag tagctgaaga
    31801 ccatgaagta ttcgtaaaat tgaatcctca gcaaaaagca cgtttgacga cagctttacg
    31861 taaaaatggt catactgtcg gatttttagg agatggtatc aatgacgctc ctgcaatgaa
    31921 agtggctgat atcggtattt ctgtagatac agctgtggat attgcgaaag aatctgcaga
    31981 cgtgatcctt ttagaaaaag atttgacgat tttggaaaga ggccttcttt ctggacgaga
    32041 aacttttggg aatatcatga aatatatcaa ggctacagca agttctaatt ttggcaatat
    32101 gttttccgtg ctgattgcaa gtacgttcct gccattttta ccaatgctgc ctttacaact
    32161 tttgtttttg aatctgatct atgatgtttc ctgcatttcc ttgccatggg atcggatgga
    32221 taaagaatat ttggacgagc caaaaaaatg gaatgcatct agtattgggg aattcatggt
    32281 ttactttggt ccaacaagtt cgatatttga tattactact tacttgttga tgtattttgt
    32341 tatttgtcct gctgtagtgg gcggaagttt ccatacattg gatagttcac agcgagtgat
    32401 tttcatcgca ttattccatg caggatggtt tgtcgaatca ctatggacac aaaccttagt
    32461 gctccatgca ctgcgtacac cgaaagtacc atttatccaa agcaacgcaa catttgccat
    32521 gtttgttatc actacattag gaattattgt cggttctgtc cttcctttta caagttttgg
    32581 tgctgaatta ggcttgatgc cacttcctgg caattactgg ttatggttat ttgctacagt
    32641 catcgcttat ctggcgcttg tgacagctgt gaagaaaatc tatatccgtc gattccaaga
    32701 actcttataa acgagaaggc tggttctttg cttctgttct ttttggacca gtcgtgctaa
    32761 actatgtgta ttgttttgga aaggattaat gtatagatga aaggtgcaat atttgattta
    32821 gatggtttgt tagttgacac agaaaaaacg tatcgtgatg gctggctttg gggatttcag
    32881 caatttgata tccatatccc aaaagaaatc gttgacgctt ggggcggaaa aaactggaaa
    32941 caaagttttg atattttagt gaaagcagca ggtagccctg aaaaagtaca ggaagtccga
    33001 gcgaagcgtg aagaatattt ttatcaacag ctgacaagcg gagccatcca cttaaaacca
    33061 tatgcaaaag aaatattggc agacttaaaa gaacgtcata tgaaactagg cattgctacg
    33121 accactgtta cgaaaagagc aacagatatc ttggatcact ttaaattagc tgattacttg
    33181 gacacgttta cattcggaga cgaagtgtcg gagaacaagc cttcaccgat tccttatctg
    33241 acagctttgg aacgaacagg attagaagct agttcagcct ttgcagtgga agattcttta
    33301 gtaggagcaa cagctgcttc acgagcagga ttaggcgttg ttttgatacc tgattccagt
    33361 tttgtccgaa attataccgt cgaagaaaag gaaaaattga aacttcttgc ggaaggaaaa
//
LOCUS       DACCVH010000025        33263 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.025, whole genome shotgun sequence.
ACCESSION   DACCVH010000025 DACCVH010000000
VERSION     DACCVH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.025"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(41..229)
                     /locus_tag="IVV98_001206"
     CDS             complement(41..229)
                     /locus_tag="IVV98_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP7806875.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="IVV98_001207"
     CDS             499..861
                     /locus_tag="IVV98_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7806876.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="IVV98_001208"
     CDS             913..2595
                     /locus_tag="IVV98_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP7806877.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="IVV98_001209"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="IVV98_001209"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP7806878.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="IVV98_001210"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="IVV98_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP7806879.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="IVV98_001211"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="IVV98_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP7806880.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="IVV98_001212"
     CDS             6430..7434
                     /locus_tag="IVV98_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806881.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="IVV98_001213"
     CDS             7435..8379
                     /locus_tag="IVV98_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806882.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="IVV98_001214"
     CDS             8379..9341
                     /locus_tag="IVV98_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806883.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="IVV98_001215"
     CDS             9368..10282
                     /locus_tag="IVV98_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806884.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="IVV98_001216"
     CDS             10308..12089
                     /locus_tag="IVV98_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7806885.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="IVV98_001217"
     CDS             12437..13123
                     /locus_tag="IVV98_001217"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP7806886.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="IVV98_001218"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="IVV98_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP7806887.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="IVV98_001219"
     CDS             16733..17542
                     /locus_tag="IVV98_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7806888.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="IVV98_001220"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="IVV98_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP7806889.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="IVV98_001221"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="IVV98_001221"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP7806890.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="IVV98_001222"
     CDS             complement(21094..21546)
                     /locus_tag="IVV98_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP7806891.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="IVV98_001223"
     CDS             21696..22646
                     /locus_tag="IVV98_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP7806892.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="IVV98_001224"
     CDS             22639..23598
                     /locus_tag="IVV98_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP7806893.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="IVV98_001225"
     CDS             23595..24350
                     /locus_tag="IVV98_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806894.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="IVV98_001226"
     CDS             24373..25326
                     /locus_tag="IVV98_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7806895.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="IVV98_001227"
     CDS             complement(25970..26266)
                     /locus_tag="IVV98_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP7806896.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="IVV98_001228"
     CDS             26621..26977
                     /locus_tag="IVV98_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7806897.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="IVV98_001229"
     CDS             26987..27886
                     /locus_tag="IVV98_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP7806898.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="IVV98_001230"
     CDS             28403..29134
                     /locus_tag="IVV98_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7806899.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="IVV98_001231"
     CDS             29279..31306
                     /locus_tag="IVV98_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP7806900.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="IVV98_001232"
     CDS             31414..32511
                     /locus_tag="IVV98_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP7806901.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="IVV98_001233"
     CDS             32818..>33263
                     /locus_tag="IVV98_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7806902.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DACCVH010000026        31248 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.026, whole genome shotgun sequence.
ACCESSION   DACCVH010000026 DACCVH010000000
VERSION     DACCVH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.026"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(40..753)
                     /locus_tag="IVV98_001234"
     CDS             complement(40..753)
                     /locus_tag="IVV98_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7806903.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            928..2352
                     /locus_tag="IVV98_001235"
     CDS             928..2352
                     /locus_tag="IVV98_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7806904.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            2651..3358
                     /locus_tag="IVV98_001236"
     CDS             2651..3358
                     /locus_tag="IVV98_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP7806905.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            3345..3668
                     /locus_tag="IVV98_001237"
     CDS             3345..3668
                     /locus_tag="IVV98_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP7806906.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(3757..4794)
                     /locus_tag="IVV98_001238"
     CDS             complement(3757..4794)
                     /locus_tag="IVV98_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7806907.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(5115..6098)
                     /locus_tag="IVV98_001239"
     CDS             complement(5115..6098)
                     /locus_tag="IVV98_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP7806908.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(6513..7283)
                     /locus_tag="IVV98_001240"
     CDS             complement(6513..7283)
                     /locus_tag="IVV98_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806909.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(7276..8211)
                     /locus_tag="IVV98_001241"
     CDS             complement(7276..8211)
                     /locus_tag="IVV98_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806910.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(8527..10176)
                     /locus_tag="IVV98_001242"
     CDS             complement(8527..10176)
                     /locus_tag="IVV98_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP7806911.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(10293..12896)
                     /locus_tag="IVV98_001243"
     CDS             complement(10293..12896)
                     /locus_tag="IVV98_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP7806912.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(12908..13957)
                     /locus_tag="IVV98_001244"
     CDS             complement(12908..13957)
                     /locus_tag="IVV98_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAP7806913.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(13983..14297)
                     /locus_tag="IVV98_001245"
     CDS             complement(13983..14297)
                     /locus_tag="IVV98_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAP7806914.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(14313..14759)
                     /locus_tag="IVV98_001246"
     CDS             complement(14313..14759)
                     /locus_tag="IVV98_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP7806915.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(14760..16736)
                     /locus_tag="IVV98_001247"
     CDS             complement(14760..16736)
                     /locus_tag="IVV98_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAP7806916.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
     gene            complement(16894..17790)
                     /locus_tag="IVV98_001248"
     CDS             complement(16894..17790)
                     /locus_tag="IVV98_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7806917.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(17783..18463)
                     /locus_tag="IVV98_001249"
     CDS             complement(17783..18463)
                     /locus_tag="IVV98_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7806918.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(18464..19246)
                     /locus_tag="IVV98_001250"
     CDS             complement(18464..19246)
                     /locus_tag="IVV98_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7806919.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(19239..20156)
                     /locus_tag="IVV98_001251"
     CDS             complement(19239..20156)
                     /locus_tag="IVV98_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7806920.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(20320..20643)
                     /locus_tag="IVV98_001252"
     CDS             complement(20320..20643)
                     /locus_tag="IVV98_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7806921.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            21431..24658
                     /gene="fss3"
                     /locus_tag="IVV98_001253"
     CDS             21431..24658
                     /gene="fss3"
                     /locus_tag="IVV98_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP7806922.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            24771..25085
                     /locus_tag="IVV98_001254"
     CDS             24771..25085
                     /locus_tag="IVV98_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7806923.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            25098..25472
                     /locus_tag="IVV98_001255"
     CDS             25098..25472
                     /locus_tag="IVV98_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7806924.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            25482..25817
                     /locus_tag="IVV98_001256"
     CDS             25482..25817
                     /locus_tag="IVV98_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP7806925.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            25900..27240
                     /locus_tag="IVV98_001257"
     CDS             25900..27240
                     /locus_tag="IVV98_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP7806926.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            27318..27992
                     /locus_tag="IVV98_001258"
     CDS             27318..27992
                     /locus_tag="IVV98_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7806927.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            28225..28659
                     /gene="dcm"
                     /locus_tag="IVV98_001259"
     CDS             28225..28659
                     /gene="dcm"
                     /locus_tag="IVV98_001259"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP7806928.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            28660..29367
                     /locus_tag="IVV98_001260"
     CDS             28660..29367
                     /locus_tag="IVV98_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP7806929.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            29357..29647
                     /locus_tag="IVV98_001261"
     CDS             29357..29647
                     /locus_tag="IVV98_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806930.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            29906..31090
                     /locus_tag="IVV98_001262"
     CDS             29906..31090
                     /locus_tag="IVV98_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7806931.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            31105..31224
                     /locus_tag="IVV98_001263"
     CDS             31105..31224
                     /locus_tag="IVV98_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP7806932.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
BASE COUNT         9610 a         6054 c         5786 g         9798 t
ORIGIN      
        1 tataaaaaaa taagctctga aaaaataatt ttcccgagct tatttttcaa caaaaacagc
       61 ttcaaaaaca aagtcttgat ataaatgtct cgataccgaa tactcgaaag gtttaccaga
      121 cgatagagca acaactttgt ctatctcaat cataaattca cctggatcta tttttaatat
      181 ttttgcgtca aattcattcg cagtatctcc tttgatacgt atgtgcgaag tctttatttc
      241 cagacccagt tcatttgtga tataagcata tacagatttc tttaaatgtt ttggttccaa
      301 gcctggtatg actgctaatg gcatgaatgt ttgctcaatc gagtatggtt gacaatcaat
      361 aaaacggctt cgtacaatat tatatacata gtcttttaca ctgatactta atttatcagc
      421 tacttttttc gatggaagtt caattgagaa agtatggatt tctgaatcta cgtgttcttc
      481 accaaccacg ctaaacaaac cttcgtttgg accaagaact cgtgagttat caattggtgt
      541 tctgacgact tcagtcccat acccacttct acttcgcaaa actccttcgg aaacaagtaa
      601 gtctacgcct ttctttactg ttaacttgct tgtatgataa ataactgcca attcatctcc
      661 tgtaggaagt ttctcaccaa ttttatactc tccatttaca atttttttct ttatatctaa
      721 gtaaatttcc atatacttcg caattttttt caatggtgac cctccaatca aaaacatatc
      781 ttcatctata ctttaacata aataaaccga taaaatccac atcaaaatta tacacacaat
      841 aaaaaagata tatatattta aacaaaacta tttactttaa gttgtaagcg gtgttatcat
      901 taagtggaaa caggaggtaa aaaaattatg acaactatga aaaagctaac ttttccagat
      961 gatttttggt ggggttccgc ttggtcagct gagcaagcag aaggaaaagg agaaacagga
     1021 aaagcagaga ctatctggga tcgctggttt aaagaacaac cttaccggtt ttatcaacga
     1081 atcgattcct ctattacaac cgatcacatc catcaatata aagaagatat agaactaatg
     1141 aaaaaaactg ggcataactc ctttcgcgtt tctatttctt gggcacgaat gtttccaaat
     1201 ggcggtaccg gaaaagtaaa tcccaaagcc atttctttct atcgaaaatt attttccgaa
     1261 atgaataata acggaatcaa agtatttgcc aacttatatc attttgacat gcctgctact
     1321 cttcaagata aaggaggatg ggaatcacgt gaagtagttg atgcttatgt tcattacgct
     1381 gaaacttgtt ttaaagaatt tggtgactta gtttgtcatt ggtttacctt caatgaacca
     1441 cttgggccta ttttaggtac ttatcttgaa gattttcatt atccaaacct cattgacttt
     1501 aaacgcggag cgcaagcagc attcttcact atacttgcac acgcaaaagc aatacaagta
     1561 tttaaagaac tagctcttcc tagtaaaata ggcgttattc taaatttgag tcctactttt
     1621 cctcgtagtc aaaatcctgc tgatgtgaaa gcagcagaaa tcgctgattt attttatacg
     1681 cggagctttt tagatcctat ggttaaaggg aatttttcta aaaagcttat cctgttatta
     1741 caagaatata atcagcttcc tgaagattat acgaaagaag atcttgtatg tatctacgaa
     1801 aataccgctc aaattcttgg actaaactat tacgagccac gtcgcgtcaa atctcgttct
     1861 tctatggtgg atacatctag tccattttta ccagagtggt ttttcgaacc acatatcatg
     1921 cctggacgac gaatgaacga ataccgggga tgggaaattt acgaaaaagg aatttatgat
     1981 ttgtgcatgg atatcaagaa ccattatgga aacatcgaag catttatctc ggagaacgga
     2041 atgggcgttg cggatgaaga acgtttcatg gatgatacag ggcaaataat tgatgattat
     2101 cggattgagt atatcaaaga tcatcttgct tacttatgga aggcaataaa tgaaggatgt
     2161 aacattaagg ggtatcatct ttggacattt attgattgct ggtcatggat caacgcctat
     2221 aaaaaccgat atgggctggt ttcactcgac cttactactc aaaaaagaac aattaaaaaa
     2281 agtggcgaat tttacaagca attaagtgat acaaatggat ttagatacga tgtagacttg
     2341 ttagttgaat aatattctaa aattccactt gaagtgaaca cattagaaaa caagaataat
     2401 gagaaatacc aataacaaat actttttctt catacttcat ttatacttgt cagtataaga
     2461 gactgtgaca aatgtagtga tcctcagaag ttaggtctgg aaatctaact tgagaagatt
     2521 tttttaaact acgtccagtc ttttttattt gtttaaaatt gaagttgaca agtcttcatt
     2581 aaaaatttag aatattcaca agtttgacga caattatgaa aatttatgtc gtgctaaagg
     2641 agttttgtta ttggatgaaa agttagatat aaaaactgcg atcaaagaca cgttacctac
     2701 cgtttttggt tatatcggta ttggacttgc atttggtatc gttgggaaag ctgccgggtt
     2761 tcatccgctg gtcgtcacgt tgatgtccct gctgatctat gctggttctg cccaatttat
     2821 cacggtcagc atgcttgcta gccatagtcc actgctctcc atcgttctct cgacctttct
     2881 agtcaattcc cgaatgattc tgatgagtat gacgattgct ccttatttca agaaaaatcg
     2941 gctgcttcaa aatctgctga ttggcacatt gctgacagat gaaagtttcg cactgggaat
     3001 gaataaattg aactatactg gacaaaagtt aaactttcgt tggatgaata cagctaattg
     3061 gatttcttat ttgacgtggg tgggttcttc tcttgttggc gcacttttag ggaattttat
     3121 tactgatccg aaaaagtttg gtttggattt cgccatcgtc gctatgttta tcgggttact
     3181 ttatcttcaa gtcatttctg atagaaacac ctctaaacga ttacagttga tcctgattgg
     3241 tctcactttg attctggtat atgtcggact gatttttatc ccaagtaact tagtgatttt
     3301 agttgtaaca ctgattgggt gcggattggg ggtgtggatc aaacatgcct tcttttgagt
     3361 ttacattgct gactatttta ggttgtactt tagcaacttg gctttctagg atcctaccat
     3421 ttgtcttact gaaaaaattc gatttgccgc aaccgttgct tgagtattta agttttgtcc
     3481 cgatcgtcat tatgtctgct ttatggttca gcagtctatt tacccaaaat atcggacatc
     3541 tgccgcagat caatctcgaa aatgctttgg cttcagttcc tacactttta gctgctattc
     3601 tttcaaaaag cttattggtg atcgtcttgg taggaattct ttccctttcg ttgattcgct
     3661 tattataaat aaaaaaacaa gagcttatgg caaattactg tcatgcgctc ttgtttttat
     3721 caaagtcaaa taagaaaaaa atcggcgtat tcttgcttat ccgttgaacg gaccactaac
     3781 aacgactttt cctaatatat gtcctgtttc tacgtctttg gttgcttgtt tcaagttctt
     3841 cgcattcatc ccatctgaat agaccttgct caatgtactg cggataatcc cttcatttgc
     3901 taaagcagca atgtgcgcta aagcttctcc ttgcgtttcg atttcatagt tatagtctgt
     3961 tttagcgaac atatactccc agtcgaagct gatagattgg tttttccaaa cacctatatc
     4021 taacggctct ttgatcccta cgatcgttcc cacatgtcca aatggtcgga caaggtgttt
     4081 gatttgatca aagtagcggg taatatcgaa taatacagcg acatactcta cttgatcgat
     4141 tcctaattca cgaaaacttt tacttaagtc gtgatgataa tcgattggat agtctacacc
     4201 tgtttttttc agccattcaa aattcttcgg acttgcagtc gcgtagactt ctaggccagc
     4261 ccaatgcgct agttgattca aaatcgaacc gacgccccca gctccgttga tcactaagat
     4321 ttttttcccg cggttggcat tttcttctgg agtcagacca aatttttcaa ataacaattc
     4381 ataagcggtc aatgaggtca acggcaaggc tgcggcttct tcatctgaaa gattttttgg
     4441 tgcaagagcg acaatacgtt cgtcaaccag ttggtattct tgattgcttc ctgctcttgt
     4501 cgttgtacct gcgtaaaaaa cgcgatcgcc gacagaaaat ttttgcactt catcacctac
     4561 agcaacaact ttcccgactc catcaaaccc taagatacgt aaagcatttc ttatcccgtt
     4621 atcttggcga agtttcgtat cgacaggatt aacagatact gcgttgactt ttaccagaag
     4681 atcccgtgaa ctgggtacag gtatctgttc tttttcatca ataaagcttt ttggatcatc
     4741 gatcgacaac ccttcataaa aaccgactac cttcattaat tccttttctg acatacgaat
     4801 tcctccttag cttcatcaag ttggagcatc catacagttt tcatttcaat atatatagta
     4861 tgctatttgt tccactttta ttcatcataa ttattctctt acttaaagta aactatttgc
     4921 acttttttgg ttaaaaaaga ggttgcgaca agacttttgt cacaacctct tttaaacggt
     4981 gttcaatcaa ctgaccctcg gtattcgctc aaaaaacgac aaaatatgag gagctatttt
     5041 tgtttggctg ttcttattac ttgatgcagg acagcttttt cacgacctct aattcacggt
     5101 gttcaagcaa gaaatcattg ttcactgaaa agcgttggat gttctttttc aaaggtgtct
     5161 aagatctctc gtacttcatc agtagatttc gtattcatca actgaactcg caagtcattt
     5221 gctcctggaa atcctttgat atagatttta aagaaacgat gtagtcctgt gatggaacgc
     5281 gggatgattt ctgaataatg atcttgcaga tctagttgca gacgaagtag tccgatcagt
     5341 tctttttctg tatgttccct cggttctttt tcaaatgcat aaggattctt gaaaatcccc
     5401 cggccaatca tgatgccatc tacgccatat ttttcggcca attcttctcc tgtctggcga
     5461 tctgggatat ctccgttgat cgtgatcagt gtttgcggag cgatttggtc acgtaaagca
     5521 atgattttag ggatgacttc ccaatgtgca tctactttac tcatctcttt acgcgtacgc
     5581 aaatggacag aaagattggc tatatcttga tgaagtaggt gactgatcca ttcttccatc
     5641 tcagacattt ccgtatagcc gatacgcgtc ttgacgctga caggcaaacc gccagcttta
     5701 gccgcttcaa tcaattgtgc cgctacttct gggcgaagga tcaagccact gccttttcca
     5761 cgttctgcta cattagggac tgggcagccc atgttgatat cgattccttg gaagcccatt
     5821 tctgccatag caatgctcat ttctctaaaa aattctggct tgtctcccca aatatgggca
     5881 accatcggct gttcatcttc tgtaaaggtc aatcttcctc gtacactgtc ttttccatct
     5941 ggatgacaga aactgtctga gtttgtaaac tcagtaaaga agacatccgg tgctgctgca
     6001 tgctttacga catggcgaaa tacaacatct gttacatctt ccattggtgc taaaacaaaa
     6061 aaaggctttg gcagctcttt ccaaaaatta gtagtcattt atttgttact ctccattcta
     6121 tcaagcagtg aagtcgcaat ctttctcaaa aacattgtca ttatactagg aaacaaaaaa
     6181 agaagcaaag tgaacagctt aaaagatgtt tctgattgag caaaaaaaga ctgtgacaaa
     6241 aatcttatca caattccttt tccggaataa atggtgttca aaagcttgca tctgcggtaa
     6301 taagtccaac caaacgaaaa ataggaggag ctatttttgt ttggctgttc ttattacttg
     6361 atgcagaaca gctttttcac aacctctcca ctaaacggtg ttcaatcagc tgaccctcgg
     6421 tattagctca acaaacgaca aaatatgagg aactattttc ccgtttgttt ctctaatact
     6481 caggtcaaaa cgctgatttc acaacctctt ttctaacttc tcaatcctct tcctttattg
     6541 atcaaatacc aagtaacggc gtacaaaaca acgatgaata gcacaagtac gatcatcgat
     6601 gttgctactg gcacatcgat tgttccaagg aatccgtaac ggaaaccgga gatcatataa
     6661 acgatcggat tgactttcga aacagcttgc caaaatggcg gcaacataga gatggcatag
     6721 aaaacgccac ctagataagt taacggctgc aagacaaatg taggcacgat cgatacatcg
     6781 tcataagact gagcaaaaat cccgttgagc agtcctgcta acgaaaacaa gattgccgtc
     6841 atcaataatg taatgatgac catgaaccat gaatacacat gaagtggtac aaagaacaag
     6901 gaaatgatcg ttacgagaga gccgacgaga atactgcgac ccactccgcc aatcacaaag
     6961 ccccaaatga tcacatgcgt aggaacaggc gctaccaaga tttcttcgat gtttttctgg
     7021 aatttttgag agaagaagga cgaagaaacg ttggcatacg aactagtgat agcagacatc
     7081 ataatcaaac caggcacgat gaattccata tatgaaaaac cacccatgtc accgatccga
     7141 ccaccgatca tttttccgaa aataacaaag tacaaggatg tcgtgatcac aggcggaacc
     7201 agtgtttgga cccagatacg caaatagcgg ttcgtttcct tgatagctaa actttttaat
     7261 gcagtaaaat aaagattaaa catttttctc ctccgtatga ttattttctt ctgtgatttt
     7321 caaaaacagt tcttctaaac gattcgactt attcctcata gaaagaactt tgattccttg
     7381 tcttgtcagc tgatcgaaga ttccgttcac cccttgattt cgttcaactt cgacagcgat
     7441 tgtctgttca tcttcaaatg tacaagcgta tccttcaatc acaggtttgg tctcatatgg
     7501 cgctaaatca aagataaatg tttcaaattg cagtttggat agaagctctt tcatactagt
     7561 attctcgatc agttcacctg attggatgat cccgatgttg cgacaaagca tttcagcttc
     7621 ttctaaataa tgcgtcgtca aaatgatcgt tgtaccattt tcgttcaatt ctcggagaaa
     7681 ctcccacatc tcgcgtctca attcaatatc gactcctgct gttggttcat ccaagatcag
     7741 caaacgtggt tcatgcatca atgccctagc aatcatcagt cttcgcttca ttcccccgga
     7801 aagcatacgt gcacggacat ttctcttttc ccaaagattg gactgcttca aatatttttc
     7861 gctgcgtttc atcgcttctt tgcgagagac accgtagtag cctgcttgat tcacgacgat
     7921 ttgctggacc gtttcaaagg gattgaaatt gaactcttgc gggactaatc caatctgttg
     7981 ctttgctcgg actagatccg tatccagatc ataaccgaag acattcactt ttccagatgt
     8041 tttattgact aaagaagtaa tgattccgat cgttgtagac ttcccagctc catttggtcc
     8101 taatagcgca tagaaatctc cttctttcac ggaaagatcg attcctcgca atgcttcgac
     8161 cccacttcca taaacctttt tcaaattatt tatttcaagc gcatttgcca tttatttcct
     8221 atctccttat agacatgatt ctttattgta tcatggaata cagcagatga aaaaacaact
     8281 tggttccagc gaaaaatcag gttgctgggc tcaggaaaat ctcctaatga aagacatcaa
     8341 tcggacgaag tcagacaacc ttttcagaaa aaacaaatcg aagataaagg attactattc
     8401 atatgtgcaa caaaaggagc gtgagacaaa agtaaagaac acttttgtct cacgctctaa
     8461 acacgtataa acggcggaag caaaagccaa gatttttgat ccaataaata ctttcgatca
     8521 cttcgcctat cccaatacat gccactgccg cttttcatca aataacgcgg cttccgtttt
     8581 tgcggtttct actaaagtct ctgggtaatc caaaactttc agcaaggcaa tcgcatttcg
     8641 ggtccttgaa ggtccttctt ttaatttgaa atcaaaactg attccttttc cttctgttac
     8701 ttgttcttca aagtggacat tctcacaata attctttaaa atctctgtca attcgatatc
     8761 atgtgtggcg acaaatgcta aagatggata ctccgcaagc caccgaacga ctgaagcgga
     8821 agaagcaatc cgttcgatcg tatttgtccc ttttaaaatc tcatctacga agcagtagca
     8881 gcgttctttg gaagccactt ggtccaacaa acgtttgatc gatttgattt ctgaaacaaa
     8941 ataactgtcg ccttcaaata aatcatcttc gattgccatg gaagtcaaca catgtccagg
     9001 ttgcagggta aactgttctg caatcgctgt ttggatcgtc tgtgctagaa tacagctgat
     9061 ggctatactt ttgacatacg tagattttcc tgatgcattg gaacccgtga ctaatgtatt
     9121 cttctgccag ttgaccggat tcactaccgc ttcttttaac aatggatgat agatatcttt
     9181 cgctgtcaca ccgccctcag taaactctgg tcggcaagtg atgggcatat aagtacggta
     9241 attcaatatt gcagcggcta cttctaattc tcccagcaat tcccacagct tgatggcttc
     9301 agttgaatgc ttttctaatt tagtgagaac gaaatgatag gagataaatg gcagcatgaa
     9361 catgatgttg acatattcaa aaatcaactc tgcttcactc ccactcttca tacgaaatga
     9421 aaaacctaat ttagggatgt ctcttaatgg tttagtttgc tgtttcagct cttcttgaag
     9481 tggtgtcggc agttttgcta gctgattggc ggctgaaatc gttgaaacca aataactcat
     9541 gctattcagc tctgtttcta gtgtttgttt cttcactaga taatagaccg tattgaatac
     9601 taacccaccg attgccaaat agattcctag tacttgtcct aaaagaagca aacccaaacc
     9661 caccagcgga agcaagccaa gaaaaataaa taaacctacg cgtccaatct ttttactttt
     9721 tccatccgct agatattgtt ttgcaaaatt atgatctttt tttcctaaac gagcgaattg
     9781 atattggatt ttttctctca gttgaggatt ttcctgataa aaagcaatca gtttttctaa
     9841 ctgctgatct tcaccaaaat caaagctgcg taaacgttga tacaacgctt ctgaacctac
     9901 actagaatag gtactgttga ttccttcgaa tacttcgaac atatccaggt cataccaagt
     9961 aagatcatcg atttcgctat cccatgaacg gaacttcttc tccgtgagcc atgcttcctt
    10021 caagctttct tctttatcaa atctcggttg ataaggaatt ttttcccatt tgctacgaac
    10081 tgtttccttt aatttcaaac gtgaaaaaat gtctaaagca actaataaaa taacagctgc
    10141 aataataatt aaaacgataa attctctttg acccatatcc ctctccgttc ctttatttgt
    10201 tagctttagt atagcactgt tgcgctattt gaaaagaggg taaaaaaaca cctttcaaaa
    10261 taaaaggtgt ttttttcttg tatattacat atttatctct catttatcaa aattgacaaa
    10321 taatcatagg gaggaattgt tgttaattct tgtttattct ccagtgcatt gacaactgtc
    10381 ccaagggaaa ggatagcctc aggtactatt ttttcttgtt ctgttggatt agctaagcga
    10441 agaacaaatc cttgttcatg aaaataagaa ggataaatcg atgatacaat taagtcttca
    10501 ggtaattcaa tcaatgaaaa tttacgagga acatcaagtt cattttgtaa tggccaaatc
    10561 ttgttatcta acctgtgaat aaatacattc agtttctgct tttgataaga aatagattgt
    10621 tctaaccgtt tttctgcctg ttttgccact ttgaactcat taaatcttcc ttcttctaca
    10681 ttaaatccaa aagtgacttt atactcacct atctcttgag ctagcggtgt ttccatcatg
    10741 acatgccctt catttgtcgt atctcctgaa gctcgcccag gtcgccaagc aagattaggt
    10801 tttccaagtt cccctgttgt tgaaaataag gttatgatta attgattttc tatacgttca
    10861 tactctttta aaccatctgc ataaaacgta aaataatgat cattttctgc cacagagaca
    10921 ctcttatcga atatttctaa attaacaggt ttctctacca tagtttctga ccaattcgga
    10981 ggaatgacat caggggtatt ttcaataaat ccgttttgaa tttgtgcaat tgatttttca
    11041 gatttatcta aaacattaat tgctaagcgc atacgatgcg agtaaacagt attatgaatt
    11101 ttgagtgtgc cttcaacgat ttgactttct cccagactga acgatatttc ataagatatt
    11161 tcttccattt cgggtttttc agataaacga tcttttaaat ctttaggaag ttgagctttt
    11221 ccgtaaacaa ctaatgtttc ttgtaaagaa tctttatata ctttagctgt ttctaatttt
    11281 agagatagtt ctgtatctcc ttctaatggt gaataatcat acgtatcgcc atcatttgct
    11341 gaatcgatca aatgaacgaa atcaagatat tgtctatctc caactatcaa attcaattgc
    11401 ccatctttaa aagaaagttt atatttattg ttacttatct cagttttgtc tatctcgatt
    11461 gctgtttcta atttttcatt atttttctca aattcaacaa cagtgtatcc tagtgctggc
    11521 acatttacat ttatttttat gtcaagttca taataagctg gttcatcaaa atattcgaaa
    11581 cctgtagcaa tcatccgata agcatttttc cgttctggaa aataaacttc tttttcaatg
    11641 atattatagg gactaccttt gaagtgtatt ttctttgaat cagctactac atgcacgatt
    11701 ttcgatccac tataattctc agtcgttgtg ttgaaaacaa ggacttcatt cgattttagc
    11761 tttaatgcat cagccatccg ttttacaata aggttttcga ttccgtcagc tatctcatta
    11821 gcttctttga ttcgatggaa aatatcttcc gcaacattat ctgaaacaca gccaccaata
    11881 ctatcatgag cctggttttg caaaatcttt ttccataacc gacgaagtag gcctttactg
    11941 atatggatac catttctttc tgcaatcagc atgagcggct caactcgttt tagaattttt
    12001 tgttccaatt taaaattttc tattttcatt tttgttctta ctgagccaat agaacgatga
    12061 acacgagagt aaaccggctg acgaagttca cctttatatt caggtaattc ttttttgttt
    12121 ctgataactt ctacataaga aggataatct gaaataatat tgtggaattt actgtattta
    12181 ttcaacttct ctacgacttg atcaaaattt aaaatcattg acttttgatc tacacccgaa
    12241 ggtactaaaa tatctttgtt ttttccttgc atatgaagca tttcaactgc ttcatccaac
    12301 ttttcttttg caaattcagg aatatcttta attgcgtcta aggtcatcat tccagtcata
    12361 taaccaaatg gaaaattcat ggcataaaca aatttatctc ccaatccttt ccagataaaa
    12421 taaggagatg gaaccatcgt ttcaaagttt aatcctcgcc aacacatgaa attatcgatt
    12481 tctacttgat gcaaaagtgt aggcaaattc gcattgaacc caaacgtgtc aggcaaatac
    12541 cctaccatca ttggatctcc atatttaagg atcgtatcac tgattccaat cattaagttt
    12601 cttaaaattg attcagcatc cactaataag gcatctgttt gtgcatacca cggtcccacg
    12661 aatagttgtc ctgttttcat cagtcgttgg ataaccttaa gcttttgcgg attgatctcc
    12721 aaatactcat cgacgattga agtttgtcca tctaaacaaa agtttacttt agggttcctt
    12781 tccaattcat ctagaacttc agtaaagacc tgatcagaca atacgatggc atcttcattt
    12841 gtaaaatacc attctctgtc ccagtgcgtg tgttgaatta tatgtgcatt taccatatca
    12901 gattctccta ctttccttct tctactgaat ttacttgttg ttctttttta tacttgatgg
    12961 attttagtgc attgaccatt aacgctgtaa ccactccccc aataacaatt gatactaaat
    13021 ataaaggtat attcgtaaca aaaggaattg ccataaaggt tgaaagcatt gtttcttgag
    13081 taacaccaaa aaatccattt agaccacatg ctactgcagt gcccaccacg atgcttggta
    13141 ttactcgtaa aggatctttc acggcaaacg ggatcgtccc ttcagtaatc cccacaaggc
    13201 ccataatcat agctgtcttt gcattatctc gttccgattc atcataaagt tttttgttta
    13261 aaattgttgc taaaaacatt ccaaatggcg gaatagcaat tcctaataac atggctgtac
    13321 taggtccaaa gcttccgctt gaaaaagaag caaccccaaa agcatatgcg attttattga
    13381 taggtcctcc catatcaaac gccatcattc ctcctaaaat agccgacatc aaagcagcat
    13441 ttgctcctga catgccttct agccaattag tcagtcctgt tgtcattgct tgaataggcg
    13501 tagctagtac ataccataat atgattccaa caactaatgt agtaacaaaa ggaatcagca
    13561 taattgattt tagactaata acttgcatcg gtacttttac ttttttcaat gcattagcta
    13621 aatagccaca agctaatcca gcaaccattc ctccaataaa tcccatacca agattttgac
    13681 acatcatccc agtgataaaa gctggtgcta gaccgggacg gtcagcaatt gaatatgcga
    13741 tataggctga aatcatcggt acgataaact gtaatcccgt ctgaccaatc attcgcagga
    13801 ctccccagaa tgtatccgtc tggtcccaaa cacctgtgcc accaaaaatg actgcaatag
    13861 aagttagtaa ccctgctgct acgacaagcg ggatcatata ggaaacccca ctttggaaat
    13921 gatttagaat ttctcttcct tgtttcttga attccattag taactccccc acgatatatt
    13981 ttttatttgt taattaatgc aattgcttca tcaatcgtct cttcaccatc ttttactacc
    14041 tctgaggtcc ctactgttaa aatcggttta ccgtcaaagc gacctcgttc tgaaacattt
    14101 gtatctactg caaatatgac aacatctgcc tcggaaacat ccgaaattga aagtttgttt
    14161 tctatcccca tagccccctg tgtttctact ttaatatcta accctttctt cttcgcaaac
    14221 ttttctaaat tagcttttgc catataagta tgggcaatcc ctgcgataca tgctgttact
    14281 gctactattt ttgtcatatg aaattcctcc ttttaaaatg atagagcttt taccaattct
    14341 tttttatttc tcgaatcttt tattctttta acaaactcgt catccatcaa tcttccagat
    14401 aattctgcta aaatacgtaa atgattagta cctttatcag tgtcttttat tgctaacaaa
    14461 aagacgagat caactggttg atcatctaat gcgccccatt caacagaccg ctttaacttg
    14521 gctacagcca ctgttgattc aattactgct aggcttttgc catgaggaat ggcgatattt
    14581 ttcccaattc ctgtggtcat atggttttct ctgtcaaata cgtctttttg aaattgtttg
    14641 tggtcagaca caaacccatt agtctctaac aatttcgata atttttcgac tacacttttt
    14701 ttatcagatg catttaaatc tatcactata ttatttatat tgattttttc actgatcatt
    14761 tataagcctt ctttcaatat ataaactaat ttttcaaacg acgaactcgt ttttaaattt
    14821 gctaataact catgattcga agcgatttca ttgaatgttt cataaatttt attcaattca
    14881 ggttttactt tttcattaag tgcaaaaaag aaaacagaat gaacaagtgt cccatcccaa
    14941 tcaattcctt ctggattaac gtagacacag attactggct tttttataaa atctacttcg
    15001 atatgcggca tagcaaaatc attcatcgct gttgaagata gtttttctct tttgattgct
    15061 ccctctagta tcccttcttt cgcgtaattt tcttttacca attttttggt aattatattt
    15121 aaaacgttca cttgattatc ctttatttgg tgggtaaaaa agcaaaatcg tttatctaat
    15181 aaatttagaa aagcatcttc tgtttgttca tttaactgta gatactgttt tacttttctg
    15241 acatctgccc ctaacatcaa aggactaaca acaataacag gaaaatttgt attttcaatc
    15301 ggaatcgtgc ttataacaag ttcatcagtg acttttctat cttgtagttc attgatgctt
    15361 agtacatctt ctatctcaac catatctgca aaaccgttat ttattctttg ctctaataat
    15421 tttgatgttc catatccgct actacaaact aatatcactt tcgttttgtc aggtttgtaa
    15481 cgatccaaaa gtgattgaat atggagtgtt acgtaagcga tttcatcttc attaaaatgt
    15541 atacagaatc tctcttcgat ttcctctaat aaatctacac ttatcataaa tgacctttta
    15601 aaagaatatt tgattttgtc cgtataaggg ttatagatat ttactcccaa tttgagtctt
    15661 ttaactgctg cattgagatg taatactaga ttattgatca attcttcatc aggataaaat
    15721 tcatttaatt taattcttac taactcttgt agctcaacac ccatatctaa ataggaaagc
    15781 ttcgtttgat ctaagtcgtg attcatagca tttttttcaa tcgaagtaat gtgaatgtca
    15841 acataagctt gttcatctat tggcacaata attgaaaatg ctttttcaat cattttgatt
    15901 aaaataagtg tattctttga gatttcttct tcagaattat tactacgtga taagaaattg
    15961 cttgtttcaa tcctttctat cgcaatagca aggtggatag ctaaagtttg aaattcataa
    16021 tctgtaaatt tcaattgtgt cttattcatg tatcgattaa gcaattcggc tacttttttc
    16081 aatatgtcct tatttaagaa attattcgct tcaccaatga aattgatatt caagtctaag
    16141 agatctgttt tactgttaga tgctgtaaag ccaccccaat aatagttcac aacttctgac
    16201 atcaaccttc ttttactttt ttcatcagct ttgatgcgca cgccatttcg atctgaaact
    16261 aaggacatcc catgcttgtt tagtcttttt ctaacatctt tcattgtgct ttctaccgtc
    16321 gacctgctca cgtataattc gtcagcaaga ttttgaatct ttagagaatc attagtattc
    16381 aataatttag caaacacata agttagacgg tcctccggag agtctgcgat attgatttta
    16441 tgactggata ataaatttcg aagtgtttct ttttttccaa taagcgaaac gcctttttta
    16501 ggttgaacca acatttgtac atctggcatt ttttggatta tttctttcaa aattaaaata
    16561 tctttgctaa ttgttttcgt agatacatat aattgttctg ataattcttt gtaagttgtg
    16621 tgctcatttt caatcaaaaa gtatagtatt ttcatttgcc gttcgctaaa ttcgatgccc
    16681 attatcttca cctcctgaat acagcttaag tgtacaatta ttatctctat tttcatacag
    16741 aagaaagttc ttgattaatg tagaagtttc taatattctt gattatttca aatcaataaa
    16801 aaagcctgca atatttatat cacaggcttt tttctctatt aaatatatat aagataatac
    16861 atttttctac tagttctcac taatcttgta taattaaacc ctccgcaact tgacggagat
    16921 ggagaagatg cccccgtcta atctagcggt catctctcct cccattcctt ccaccaattt
    16981 ttttgacagg taaagcccga ttccgctaga ttccgtattt gtgcggctgg tattttcggt
    17041 ataaaaacgc tggaagactt tttcaacaga ggtttgcgtt cctggtttga taggattggc
    17101 cactgttaat cgaatgaatg gatcctcttt tgaaaatgtc acctttgctt gtccatctgc
    17161 ataacgcaat aaattctgta tgatattttg cagcactcgc agcaacatga gcggatctgc
    17221 taatacagtt gtatttatcg agtgttcagc gaacgctacc tcgatatttt tctcagaaaa
    17281 ttgttcataa aaagagaaaa atacttcttc cacctcttta gaaaaagaaa gcgtatggag
    17341 atccatttct ttttgcttcg tctctattcg agcaagatca taaaactgat ccgtcatact
    17401 gagtaatctt gcaacagatt gtttgatgat cgttaaatac ttctcccgtt tctccgtatc
    17461 ctctacctgt tccagtaatt gtacataacc gttaatagca gtcaaaggag ttctgagatc
    17521 atgagaaagg ccgacgatcg atagtctgat gttttcttcc atttcttgaa atgcttgtcc
    17581 tttttgttca ttttcatcca accatgtatt cagtgcatct actaggtcca ttagattctt
    17641 ttctcgaaat tcgactgaaa gacgaccacc atattcttgt cgttcagaaa gagtggcgat
    17701 tttcttagtt aatctcttga tttccctttg caggaagaaa ataaaacttc ccataaagat
    17761 aacaacgaga agcaacagcc atttaatcaa atctaaaccc cactccccac accgtatgaa
    17821 tatacacagc atgtgccttt gctagcttcc ctcgaagatt ggaaatatgc atattcactg
    17881 ttttctcact atcaaaatat ggttcttgcc aaactgtttc ataaagattt gctcgcgaaa
    17941 atactttttt cggatgttct aaaaaaagct tcagcagatc gaattctctt cctgtcaaat
    18001 ggacagccac accattcaca tttacatccc tcgactcttt gtccagtaag atttccttgt
    18061 aatagatgcg ttgcgacaga tcttttactt ggacagaagt ctgatgacga agttggatgc
    18121 cgattcgtaa caaaagttct tcgatatcaa atggtttcgt cacatagtca tccgctcctg
    18181 ctgccaacaa ggaaacttta tctctttgat cgctttttgc tgaaagaacg atgatcggaa
    18241 cattcgatgt ctgtcggatt tctgctaaca atgcttcacc tgaaagccct ggaagcatga
    18301 gatctagaag gatcaaatcg acaggatatg tgcttaacaa taattttcct tccgtacctg
    18361 aataagcatc aagaagtttg tatctctgtt caagaacctc ctccagtaag gaatgaacag
    18421 cttcatcgtc ttcgataatc aaaatagttt ccagcaggac cacctactta atgtcagatt
    18481 tttggaaaat aaacattcct agagctgatg ataccacgat tgttactaga ctgaccagaa
    18541 tcattttcgg tgcttgcgaa taagttgctt gttgcgcaaa gtccgtatac atgagccacg
    18601 tttccgtaaa ccactccgtt agaaattcca agcctttgat ttttgcgaaa acaccgggaa
    18661 tgaaggccgt tcccatgata taaagaaaag aaagaagcaa actgacactg gtacttctag
    18721 tgatgaatgt caaagccact ggaacagata atgtccctaa tgtcagcaga agcaatacag
    18781 gaaatacttt tagaacataa tttccatagt ttttgattcc ctcaacttca ccaaatccga
    18841 aagcaagtgt gtaagcaagc atggctagtc ccgtgatcaa aaccacgcca agtgttgtga
    18901 tcaaaagcgt aacgagaagt ttcgacacat aataagtcat tcgattccgt cctaaagata
    18961 acgtattgcg aatcgtaccg ttttgaaatt cttccccaat ataaaagcac gcaaatgctg
    19021 cgaaagccag aagaatccat gcagccattt tttctaccat taaaatccct gttgcaccgt
    19081 tgatgactgt atccgttgct tggtttaatt cattgccgta ttttgtatgc atataccatt
    19141 cgttccaaga ataaaaaagc ggaagtacga ccatcagtcc tagtgagacc cacattttac
    19201 ggctcttcca tacttttatt ttttcagcag ttaatagatt aaacatgtgg attgcctcca
    19261 gttaattgta agaaataatc ttccagtttt tgcccaacta ggtgaatacc atccacagga
    19321 acttttgctt ctaccaatgc ttgattgatg gctgctactt ggtcaattcc ttcaaaaagc
    19381 tggataacac ggctagattg tacaaaataa tccctataac caagagagtc gagaaccgtt
    19441 actgcttgtt ccgtcgccga agtgtcaatt tttataaatt gacgagattc ttgtgccaat
    19501 tcttctttcg ataattcttt gatcaagtgt ccttcatgca aaataccata gtgagtggcg
    19561 atctgtgaca attcatctag caagtggcta gaaagcaaga cggtgatgcc ccgttctttt
    19621 accaaacgtt ggatgatttc tcgcatttct gccatccctg ctggatccat cccattcgtc
    19681 ggttcatcca aaatcaaaaa ttctggattc gtgatcagtg catttgcaat agctaaacgc
    19741 tggcgcatac ctaaagagaa attctttgct ttctttttcc ctgtattttc caatcgcatc
    19801 attttcagca ggtcttcgat ttctctatcc gacacaccgc cgttcgctgc ttggatacgt
    19861 aggttatctc ttgcagttaa ttctggataa agagcagggg tttcaatcga ttgacccata
    19921 cgtcgtcttg ctgcctgcaa atccgtcgtt ccaaataatt cgatcgaacc ttcatcaatc
    19981 gagatcaaac ccataatagt tctcataaag gtagacttac ccgctccatt ttccccaatc
    20041 aatccataga tcattccacg tttgatttcg attgatactt tatctaatgc tttggcagca
    20101 ccgtattttt tggttatacc agttgctttc aagaccgttt catttccaaa atccatactt
    20161 atccttcttt cttattgatg agtgaagtat agttgacggg tataaagaaa gcagccagaa
    20221 atgtataaag aaagtgtaaa ttttccaatt gaatgtcaaa aaaaacaatc ggacaatacg
    20281 tgtctttcct attatcaggc agtttgttat acgcttgtat cagtttcctg attctttctt
    20341 ttcgaccaaa gtcgtttctc tgtattcctc ttcactgaaa atttttgctt ctttcagatc
    20401 aagcttgagt aattttacca gaccggttat aaggataact atagcaagac tccctcccag
    20461 aaaaattaga ctgtctcgca gacgtggttg cgttgtcttc caatcaaaga gcgcaccaaa
    20521 cagtgctaat ccaagtggac tggccaccat ggtaatcgtt gttatcgttg acataagtcg
    20581 tccttgtata tgcgttggaa cttctcgctg aagccagacc atataaaaag caaaagaaaa
    20641 cattaatcct taaaaacgga cttatgaaaa ataatacatg ccgtttggga tttacaatta
    20701 gctaccaaat aagaggttat gacaaaagac ttttcacaat cccttcttcc gaataaacgg
    20761 tgttctcctg ccaactcctc ggtcacaagt cacaatattt atcaaacatg agaagcaatt
    20821 tttgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct cagaagcgga
    20881 taaataatat tgtttgatga tactttatct ttttcccgtt tgtttataga tcgaatgata
    20941 ttatagacca agaatcctac ctattaacat agctaaaaac acaaaaaagg cactttccaa
    21001 attgtggaaa gtgccagaaa agttaggatt aaggtaactg cgctcagcat tgcttcgccc
    21061 agtacgattc tcgtaactcg tgaactcgaa cgataatcgc aattaacgtt ttgagaactg
    21121 tgaagcttta cgggctttct taagacctgg ttttttcttc gtatcattga ataagtttga
    21181 aaaaccttga tttataaagg ttttcccgta aatatatttt attatatttg attaaatttg
    21241 aaatgtttgt gttctaaaat gtgttctaat ttaaaggcag tatatttcgt attttagatt
    21301 aaatttttag gctcattcat tctcaaatcc attctattca gtcaataaaa attttaaaaa
    21361 gactttataa acaaagatgt tcaagcgagc atcttatttt tttgtgctta atttgaaagg
    21421 agaacatttc atgtataaaa aacaaaaaaa gaaattatgt gtattaacta ttttgagttt
    21481 ggctgttcaa gcaattgttg gagcaattgc tcctacgatt acttttgctg atgaaattac
    21541 ccatccacaa acggtaaccg tagaactaga tttagcacat caatatgctg ttgaaggaac
    21601 ttttagtgat ggtcgtccaa tgtcagaagt cactgttccg cattatgcag tgtacaacgg
    21661 ctttaaacaa gatattttct gtattgaacc aggagtcccg atttacaatg agttcactcc
    21721 tggctatgag aaaaacccgt taccagatat gtccgataaa gccaaattag tttccgtttt
    21781 atggaaaaaa gtaggtacag atgcagatac tcatattgtg gcacagaaga tgatctggca
    21841 agaagttaat gggtataccc ttcactcaat aaaacgatca gatggtagtg ccgtaaatat
    21901 cgcagccatt gaggcaaaaa taaatcaagc cattgacgat tatcagaaga aaccaacctt
    21961 ccataatagt acggctaaaa cagtattagg gcaatcgact actgtgacgg atacgaataa
    22021 tctgaatttg tcagagttcg atgaggttgt ggaaaatgcc gcaaacattg attatcgtgt
    22081 gaatggtaat cagttgataa tcaccccaaa tgccaattca aaagaaagtg gtgtgctgac
    22141 gcttaagaaa tctgctggta ccggaacacc tgtcgcctat aaaaaggctg gccaacagac
    22201 tttaatggcc ggggcgattg ataaacctaa tacctacaca atcaaaattg atgtggaaac
    22261 ggagggttct ttaaagatca aaaaagtcga taaagaatcg ggtgatgttg taccaggaac
    22321 ggttttccat ttagactttg gaaaaacttt acctgcaaaa gacgtgacta ctgacaaaga
    22381 aggcattgct acattggatg agattcctca tggtacaaaa gtaaccatta ccgaaaaatc
    22441 agtaccggcg ccttatacga ttgataccac ccccatgact accaccatta aagcaggcga
    22501 aaccatttac gtgacttcaa aaaacgcacg ggaaaaaggg caaatcattc tggataaaag
    22561 cggagttgaa acagggagtg atctttggaa tgacaattat tccttagctg gtaatacgtt
    22621 tgccattcgc aaagacagtc caaccggtga aatcgttcaa gaaatgacca cggatgaaaa
    22681 cggtcatgcg gaaacaccaa aagagattgc taatgcgttg gaattgggaa cctattatgt
    22741 gaccgaaact aaagctagtc atgggttcgt gaatacgttc aaacctgtaa aagtcgaatt
    22801 gaagtatgcc aatcaaaccg tagcccctgt taccagtaac gtaaaagggc aaaatcaaga
    22861 agtcactggc gaaaccactt tgacgaaaga agacaaagat actggggata aagcacaagg
    22921 taaggcagtc tttgagggtg ctgaatacac cttgtttact gctaaggatg gaaaagctgt
    22981 taaatggagt gaggctttta aaccagagtt agcgaaggga acgaaaggtt ctgatgaaac
    23041 ggtcactttg actttagacg aaaagaacca agttgccgtt aaacatttag ctatcaacga
    23101 gtattattgg caagaaacaa aagcgcccga aggatatagc cttgatgaaa caaagtatcc
    23161 tgtatccatc aaaaaggtgg atgatagcga aaaaaatgcc gtgattaccc gaaatgttac
    23221 ggcaaaagaa caagtgattc gctttggctt tgatttcttt aaatttgctg gatcagctgc
    23281 gggcactacc gaaactggct tcaatgatct gacctttaaa gtgtcgccat tggaagggac
    23341 caatgaaatc acaggtgccg aagatgaagc gaccacagct tataacgagc aattagggtt
    23401 tgatggttat ggcaagtttg aaaatcttcc ttatggggat tatttacttg aagaagtaga
    23461 agccccagaa ggttttcaaa agattacgcc attagaaatc cgttctactt ttaaggaaaa
    23521 caaagaagac tttgtgaaga gtgagtatgt ctttaccatt accgaacaag accaaaaaca
    23581 accaattaaa acggtgaccg ttccttacga gaagctgacg aacaaagcat tttctgttag
    23641 tttgaaccgt ttaatgctct atgatttgcc tgaggaagaa gatagtttaa cttctcttgc
    23701 gacttggaaa gacggaaaca aagaattaac ttctctggat tctaccgagc tagttgataa
    23761 attgagttac aatctacatg aaatcaaaga agactggtat gtggtagcgc aagccattga
    23821 tgtggatgcg acaaaagctg cccaagaaaa agatgaaaaa gccaaaccag tggtgattgc
    23881 agaaacaagc gcaacgttgg cgaacaaaga gaaaacagga acttggaaaa ttcagcataa
    23941 attaaccgcc gaacaagttt taaataaaac tattgtctta ttcaactatg tgtatgaaaa
    24001 taaggaagct tttgaagcag gcgataagcc agtagcgaag gatgttagct tgaataacca
    24061 agcccaaact gtcagttgta cagtggaaca ccatgtttct atccaaacaa aggcccacct
    24121 agaaaacggt tctcagacct ttactcatgg tgatgtggtg gatatgtttg atgatgtgtc
    24181 gattactcat gatgtactgg atggctcaaa agaagctttc gaaacaattc tgtatgcttt
    24241 attaccggat ggtacaaaca aagaaatttg gaaatctggc aagattgatt atgaagtaaa
    24301 tgataaagaa ttcaccaaaa ctgtgcttgc gaaaaaagta gataccggaa aatatccaga
    24361 aggaaccaag tttacttttg cggaaatcaa ttacgataaa gatgggaata tcaatggaaa
    24421 acacaatgaa gatttgaaag aaaaatctca aaccttaaca ccaaaagaag ttccaaccat
    24481 actaagtacg ccgaaacaac cggaaacacc aactgttcca agtggctctc aagaatctag
    24541 tcccacagtg aagaccttcc ctcaaaccgg ggagaaaaat tccaatgttt tactgttcat
    24601 tggttttact ttgatttttg cgacggcggg ctattatttc tggaatcgcc ggaactaagg
    24661 tgatgagatg atacaagtaa atcctaagaa ccaacgtgcg cgaccgcctc ctaaaaaagt
    24721 agtcgcgcta tttttgtatc caaaactaac aatgaaaaga ggaaaagaag atggaattga
    24781 aatttgtcgt gccagatatg gctgaaacct ttggaaagtt aagttatgcc ggtgaaggag
    24841 aaattataac agaaggatat ggacggaata ctacggtgat tggtcgcagt tatcatttgt
    24901 attccagtaa gcaacgggcc gatgatattg aggtggtagt agctgcggaa gccggtgaaa
    24961 aggattttga tcaagaccaa ccgctaaaag ccgtgaatcc ccatttggtt gccaaaggct
    25021 atgagattga gaatcgtggg tttactgatt acgtgttgta tgttgatgat ttagtgaaag
    25081 cataggagga aaagaagatg agattaacag aaggtattgt cgtagattca ggtttaacat
    25141 ttgggaagtt gcgtttttcc gcattacgcc gagaagtacg gaagcaaaat gaggatggaa
    25201 caattggtaa tgaggtaaaa gaacgaacct ataatttaaa atcctctgca caagggcgaa
    25261 tgattcaagt tagtatccca gctaatgtac ccttacgcga gtttgcttat gatgcagagg
    25321 tagagttggt caatccaatc gtggataccg ttgccaatta tgtttttcga gaaggaacta
    25381 ccgttaattg gttcattaag gcggatgatt tagtcttgaa gcggcagccg aatcaaggaa
    25441 atcctacgaa ccaaaatgaa agaaagaaat aggtgaagat tatggaaatt aatgttgaac
    25501 atattttaga ttgtctcgat caatatggaa aaggcgagct gactgaggaa caactcgtta
    25561 aagcattaac ctctgatgaa aaaatgtttc tgattataca tcaaggttta cttggagaaa
    25621 atagcgacag tgaagaagac tctgatgtac tagactggtt aggagaagaa gagtctttct
    25681 ttatagttgt cgaagtaaat gaaaacttat gtcggcaggc agaatccatt ttggaagaaa
    25741 ttggtgtgga gatgccggat gctattgaag gctttttaaa tcaattggtt gaaacgaaac
    25801 aactcccctc ctcgtagcag taaatgacta gcataacttt ttgaaattgc ctaatgaaat
    25861 cctattgggc tttttcgatt ggaggtggaa accatcaaaa tgtacaaagg acatcgcata
    25921 cgcgcaggag atcagcactt ggtttatcac tttgttcttg gctggctact cgctctgttc
    25981 atcggttgga tgagcgtctt ttattttcaa gagtttagac aatttgatat ttctaagcta
    26041 tcactttcta ctattgaaat cgtttggtct ataaaagatt tagtatgtct gcttggaagt
    26101 ctcgcttttt caggagctat gatattgctt tatattcact tttttcttga tcattggcga
    26161 agcttgtggc atcgacaaaa gctagctcgg atgattctag agaaccattg gtatgaagtg
    26221 aaacaaactc aaagtgaagg ctttttcaaa gatttgaata gtagccgaac cagagagact
    26281 atcagttact tccccaaaat ctgttatcga atgaaagatg gattactgtc tattcgcgtt
    26341 caaatttcac ttgggaaata ccaagatcag cttttaaaat tggaaaagaa gttagaaagc
    26401 ggactgtatt gtgagttagt agaaaaggaa ctcaaagact cctatgtgga gtatacttta
    26461 ctgtatgata tgatcgccaa tcgaattggg atagacgaag tagtggcaga aaatgggact
    26521 ctgcgattga tgaaaaatca agtatgggct tatgattctt taccccatat gttaatcgct
    26581 ggtggcacgg gtggagggaa gacctatttc ctcctcacca ttatcgaagc actattgaag
    26641 tcagatgcag aattgtttat cctcgatccc aaaaatgcag atttagctga tttaggtacg
    26701 gtgatgcctc atgtttattc acaaaaggaa gaaatttctg cttgtgtgga agatttctat
    26761 gaacgtatga tggctcgtag caaggcaatg aaagaaatgt ctaactacaa aacaggagag
    26821 aattatgcct atcttggact tccacccaac tttttaatct ttgatgaata cgtggcttat
    26881 atggagatgt taacgacgaa agaaagtgcg gtgattttga ataagctcaa acaaatcgtg
    26941 atgttgggtc gtcaatctgg tttctttctg attttggctt gccaaaggcc ggatgcgaaa
    27001 tatttaggag acggaatccg cgatcaattc aactttcgcg tggctttggg tcgtatgagt
    27061 gaactcggat attccatgat gtttggggag gtcgaaaaaa acttctttat gaagcacatc
    27121 aaaggtcgag gttatgtgga tacaggtggc agtgtgatta gtgagtttta tacgccactt
    27181 gtaccaaaag ggtatgattt cttagattca attagtaaat tagaaaagat gaatgattga
    27241 gtgatcttca atactgactt tatacttcaa gtaacgtata atacttttat atagtaggaa
    27301 gaaaggggat aattaatatg gaaagtaatg attcttattt agagtatgca aaagcaaata
    27361 aggataagtt tatttcttat attatcaaag ggaaatcccc cgaagttgga cgagacgcag
    27421 tttttatggc agggagtcct ggggctggaa aatcagaggt tgccattgga ttagctgaga
    27481 attatgataa ccatgtgatt attgatgcgg attactttcg cacccagttt cctgattata
    27541 atggaaaaaa ctctagtctc tttcaaaaag catcttcttg gttggtagag caggcattta
    27601 gatatgtctt agatcatggc tattctttta ttctggatgc aacttttgca atattaagtg
    27661 ctgaaaaaaa tatctcgcgg gcgttgaaaa aacattttcg agtgacgatt ttctatgttt
    27721 atcaagaccc taaaatcgct tggaaattta cacaagaacg tgaaattgca gagggacgtc
    27781 atgtgccgaa aaaggcattt attaacgctt ttttcaaatc aagagagaac attgcaaaag
    27841 taaagagtaa acatccagat gtattgcttc atatcataat aaaagattat acgaataata
    27901 tttccgaagt tcattatgct acggataatc tagaattatt tttaccacta gggtatagta
    27961 ggaaagattt ggaggttcaa ttacatgact gagaaagaac aagtaacgaa aattgtaaag
    28021 aaatacaata agagcattgc ggatttatcg gaaaatgcta ctgcaaaaga gttcaaaacg
    28081 gtgattaaat atgtagccga tcaggccaat gaaaaacaac ggaaattagt tggattaaat
    28141 aaaaaatagt aggacaaatt aataatgtat gagccaagag caaaatgttc ttggcttttt
    28201 tctttgcaat gaatgaggta atgtatgaga tttttagatt tattcgccgg tattggtggc
    28261 tttcgtttag gtatggaaca ggcgagccat cattgtatcg gtttttgtga aattgataaa
    28321 tttgctagac gtagttataa agcaattcat gatacaagta aggaggtgga aatgcatgac
    28381 atcacaagtg tatcagatga gtttattcaa tccctcggac cagtggacat cctttgcggc
    28441 ggatttccgt gccaagcttt ttcaattgcg ggaaagcggc aaagattttc cgatactcga
    28501 ggtactttat tctttgaaat cgctcggttc accactcttc tccgacctaa gcttttattc
    28561 cttgagaacg tccgaggatt gctcaatcac gaaggagggg ctacgttcga gacgatcctc
    28621 cgaacgctgg atggattggg gtatgacgtg gagtggtagg tgcttaactc aaaggcctac
    28681 attccccaaa gccgggagcg gatattcctt atcggacatt ctcgagacgc atgtaccgaa
    28741 caagtatttc ctatcattgg accgtcttca acatctgatc aaaacatcag aaatttggta
    28801 aatatcaatc cttccaatcg aggaatgggt ggacaagtct atggttcaga tggcgtagcg
    28861 ccaaccttaa caggtgatga aggaatcaaa atcgcactgc cagcaaggga tggaatctct
    28921 gtagcaggac tattaccggg aaagtttgaa caaggtaatc gagtttatga agttactgga
    28981 accgccccca ccttgtcaac gaaacaaggt ggtacaaaaa tcatgattcg aaaaaatgaa
    29041 acagaatatc aagaggtgaa gccagaagac agtgtgaatc tggcttttcc taattccaca
    29101 agtcgccgag gtcgtctggg aaaacagagt gttcatacct tactaacagg agaccaacaa
    29161 gcgatcgtca cggatcagta tcaaattcgg aagctaacac ctagagagtg ttggcgactt
    29221 cagggctttc ccgattgggc ttttgatcga gattctcaag tcaattcaga tagtcagttg
    29281 tataagcaag ccggaaactc tgtaacagtt ccggtcattt ttgatattgc cagaagatta
    29341 aaagagttgg atgtacatgg tttatgatga gttgattgga gaaatttatt gggtgattgg
    29401 aaagattcag tcagacccag aattagaaga acaattgcga cggttaaaat ttgatattcg
    29461 caagaatggt gtcaaagtcg ctggcgatcc atatttaatg aatgaggaga cggatgctcg
    29521 aattgaaata aatcaagtaa ttgcagaatt tgagcggatt gcggaccaag caaaagaacc
    29581 agatattcgt caatacttgt tagaaatgaa agcagagttg gaagtaaatg gtattacaga
    29641 tgagtaacct aaaccaacac aactgactgt taggcgctga ccgcggagga ttcgcgaagc
    29701 agaaatcctc cgtggtgctg tgcctgttca tggacggcgt tagccgacca tgatgtctca
    29761 cccccgtatc taacaggggg gtacaaaaac acaaaaaata agtaagcaac cattaagaat
    29821 gcttgttgta tcaaagatag taagtaattt gtataggtgt taactcattt gaaaaagtta
    29881 acaccttgaa tttggaggtg agaacttggc acaacggaat ttagattatc ggctattaaa
    29941 agaccgacgc aacgaatacg gcgtttcaca aaataaattg gctacggctt gtggacttag
    30001 tcggccgtac ttaaatcaga tagaaaatgg tggcgtaacc gcatctataa aaaccatgag
    30061 gaaaattttt gaccaactgg aaagctttaa tcccgatttg cctttgacgt tactgtttga
    30121 ctatgtaagg attcgctttc ccacaacgga tgcacgaaaa attattcaag aaattctcca
    30181 tttgaaattt gagtatatgc tccatgaaga ttatgccttt tactcctatc aagaacagta
    30241 tgtcatgggt gatattgtgg tgatgttgtc tcatgaagaa gataaaggtg tgcttttaga
    30301 attaaagggg cgaggttgcc gacaatttga aactttttta ctcgctcaaa agcgtagctg
    30361 gtacgacttt ttcgaggatt gtctaaaggc cggtggcgtg atgaaacgct tggacttggc
    30421 aatcaatgat cgagtggggc tattggatat acctgagcta acgaaaaaat gtcagaagga
    30481 agaatgtatc tccttgtttc gtacctttaa aagttatcgt tccggggaac ttttaaaggc
    30541 tgatgaaaag gacggcatgg gcaatacctt atatatcggc agtctcaaga gtgaggttta
    30601 tttctgtttg tatgaaaaag actatgaaca atatatcaag ttagggattc cattagacca
    30661 aactgagacg aaaaatcgtt ttgagattcg actgaaaaat gaccgtgctt ttcatgcgat
    30721 tcaagatttg ttaaaaggtc gtagcattga gagcaccacg ttttccatta tcaatcgtta
    30781 cttgcgattt gcggataaag tagaaggtaa aaggcgaacc aactggccct tgaatgaaca
    30841 atgggggcgt tttattggac ggaatcggaa agagattcaa ttaacttccg agccaaaacc
    30901 gtataccatt gaacgaacct tgaattggct aggccgacaa gtcgccccta cgtggaaaat
    30961 ggctaaggag ttggatcgat tgaatcggac aacctatatc caggatatgg tacagaatgc
    31021 acgcttatca gaccgacata aaaagatttt ggagcaacaa agtatggcaa ttgaaaattt
    31081 gattatatga aaagaggaat cgtcatggga attgtaaaag atattttttt ggtatttggt
    31141 ggcagtatgc ttggtgttac tgtgatgtgc ttgatgaatg caagtgcagc agcggatcga
    31201 gcaatggaaa agaaaggaaa gtgacaagat gaatttcgga caaaattt
//
LOCUS       DACCVH010000027        30794 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.027, whole genome shotgun sequence.
ACCESSION   DACCVH010000027 DACCVH010000000
VERSION     DACCVH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.027"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            611..1939
                     /locus_tag="IVV98_001264"
     CDS             611..1939
                     /locus_tag="IVV98_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP7806933.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2141..2974
                     /locus_tag="IVV98_001265"
     CDS             2141..2974
                     /locus_tag="IVV98_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP7806934.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2990..3727
                     /locus_tag="IVV98_001266"
     CDS             2990..3727
                     /locus_tag="IVV98_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP7806935.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3882..4850)
                     /locus_tag="IVV98_001267"
     CDS             complement(3882..4850)
                     /locus_tag="IVV98_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP7806936.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5082..5915
                     /locus_tag="IVV98_001268"
     CDS             5082..5915
                     /locus_tag="IVV98_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP7806937.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5949..6788
                     /locus_tag="IVV98_001269"
     CDS             5949..6788
                     /locus_tag="IVV98_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7806938.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6814..7374
                     /locus_tag="IVV98_001270"
     CDS             6814..7374
                     /locus_tag="IVV98_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP7806939.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7573..9294
                     /locus_tag="IVV98_001271"
     CDS             7573..9294
                     /locus_tag="IVV98_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP7806940.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9459..10601
                     /locus_tag="IVV98_001272"
     CDS             9459..10601
                     /locus_tag="IVV98_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7806941.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10617..11828
                     /gene="thiI"
                     /locus_tag="IVV98_001273"
     CDS             10617..11828
                     /gene="thiI"
                     /locus_tag="IVV98_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP7806942.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12401..13048
                     /locus_tag="IVV98_001274"
     CDS             12401..13048
                     /locus_tag="IVV98_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP7806943.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            13441..16086
                     /locus_tag="IVV98_001275"
     CDS             13441..16086
                     /locus_tag="IVV98_001275"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP7806944.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16396..17709
                     /locus_tag="IVV98_001276"
     CDS             16396..17709
                     /locus_tag="IVV98_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP7806945.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17699..18352
                     /locus_tag="IVV98_001277"
     CDS             17699..18352
                     /locus_tag="IVV98_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7806946.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18407..19099
                     /locus_tag="IVV98_001278"
     CDS             18407..19099
                     /locus_tag="IVV98_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP7806947.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19249..19449
                     /locus_tag="IVV98_001279"
     CDS             19249..19449
                     /locus_tag="IVV98_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7806948.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(19703..21382)
                     /locus_tag="IVV98_001280"
     CDS             complement(19703..21382)
                     /locus_tag="IVV98_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP7806949.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(21384..21596)
                     /locus_tag="IVV98_001281"
     CDS             complement(21384..21596)
                     /locus_tag="IVV98_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP7806950.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21989..23719
                     /gene="efrA"
                     /locus_tag="IVV98_001282"
     CDS             21989..23719
                     /gene="efrA"
                     /locus_tag="IVV98_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP7806951.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            23716..25476
                     /gene="efrB"
                     /locus_tag="IVV98_001283"
     CDS             23716..25476
                     /gene="efrB"
                     /locus_tag="IVV98_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP7806952.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            25571..25768
                     /locus_tag="IVV98_001284"
     CDS             25571..25768
                     /locus_tag="IVV98_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7806953.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25921..26406
                     /locus_tag="IVV98_001285"
     CDS             25921..26406
                     /locus_tag="IVV98_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP7806954.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(26510..27103)
                     /gene="clpP"
                     /locus_tag="IVV98_001286"
     CDS             complement(26510..27103)
                     /gene="clpP"
                     /locus_tag="IVV98_001286"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP7806955.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            27283..27810
                     /locus_tag="IVV98_001287"
     CDS             27283..27810
                     /locus_tag="IVV98_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP7806956.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27901..28638
                     /locus_tag="IVV98_001288"
     CDS             27901..28638
                     /locus_tag="IVV98_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP7806957.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            28642..29559
                     /gene="miaA"
                     /locus_tag="IVV98_001289"
     CDS             28642..29559
                     /gene="miaA"
                     /locus_tag="IVV98_001289"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP7806958.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            29561..30790
                     /gene="hflX"
                     /locus_tag="IVV98_001290"
     CDS             29561..30790
                     /gene="hflX"
                     /locus_tag="IVV98_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP7806959.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10170 a         5271 c         6572 g         8781 t
ORIGIN      
        1 tcctactgcc ggagtaaata aagcttatgc aaagaaaaag aaatccaatc acttgggttt
       61 ctttttcttt tattattatg atgaatcaag ctttctgttt ttgtcacgta tgttgtaatc
      121 tttacgaaag agtagagttg gctactcata atcaaccata cttcccatca tcgctaaata
      181 cgaaataaat cagcattcct acaccaatca aagcacaagc tgcaccaaga aaagggatga
      241 cattcccaaa gttatctgta ttcataagta tgccaccacc cacaaacaaa aagccgccag
      301 caatcaggtt tttcatttta ttcatctcct ttcttacgtt atagtatttc cttctttcaa
      361 tgagtatttt gaaagctatc ttattgtatg atgttcttct aggcctcttc tttattatac
      421 aggccatttt cgttatctca tagaaatatt cctttttatc tgaaaactat tgtataccgt
      481 atgacatttt tcttcatgaa gttgtaagta tattctcatt caaatgaaaa tttcatcata
      541 gaagagattg tatttctaaa ttcttaagag taaaatacga agtataactt ggatttggaa
      601 ggatgattgg atgaaagcta ttacgcctga tatgacaaca aaatttaaca aacagtttca
      661 agcaaatatc aaacagcagg cattgcagcg ggcagttgtg aagaacggaa ttactgcttc
      721 tgctgaaaat gtttcagcac atgtggagaa tacaccggta ttttctatag atttggctac
      781 ggggaaagtg gctaatcaaa tgcaatcggg gcgttgctgg atgtttgctg cactgaacac
      841 attccgtcat aagatgctga atcaattcca tttaaaagag tttgaattat cacaaaatta
      901 cacttttttc tgggataaat atgaaaaggc aaattatttc tatgaaaaca tcattgcaac
      961 aggaaaagag gcaatcgata gccggaaagt agctttctta ctcgctactc ctcaacaaga
     1021 tggcggccaa tgggatatga tcgtttcatt attccaaaaa tatggcgttg tgcctaaatc
     1081 ggtgatgccg gaaagtgcga atagttcaaa ttctcgagat ttgaataact acttgaacaa
     1141 attactgcgt aaagatgcag tagtgttacg gaaaatggtt gctcaaggag aaacattaga
     1201 cgctattgaa gaaaagaaag aagaaatgct agaaagcatt tataacttct tagctatctc
     1261 attaggaaca cctccaaaag aattcgattt tgagtaccgc gatgaagaaa agaactatca
     1321 tcttgaccga ggactgacac cacaaatttt ttatgataaa tacatcggtg taaaattaga
     1381 tgattatgtt agcgtgatca atgcaccaac aaaagacaaa ccattcaatc gttcttatac
     1441 agtagagatg ctaggaaatg tcgttggcgg gaaagaagtc aaatatctga atgttgatat
     1501 ggaaactttc aaaaaattag cgattgctca gcttgaagaa ggagaatctg tttggtttgg
     1561 ttgtgatgta ggtcaatctt ctactagaac tagtggcatc atggccttag atgcttattc
     1621 aatggatgat ctatttgata cggattttac aatgactaaa gctgaacgtt tagattttgg
     1681 agaaagtctg atgacccatg cgatggtatt gaccggtgtt gacttagtag acgggcaatc
     1741 aacaaaatgg aaagtcgaaa atagctgggg cgaaaaagtt ggaaagaatg gcttctttgt
     1801 tatgagtgat gcctggatgg acgaatatac gtaccaaatc gttgtaagaa aagatttatt
     1861 gacgaaagag caattaaatg cgttcaatga agaaccaatt gttctatctc cgtgggatcc
     1921 aatgggtgct ttagcataga cgagtatttc aatgaagagt atgtagtaaa gataaaaaga
     1981 gctggcttaa gccagctctt tttatcttta aagtccattc cctgtttttt atggtccctg
     2041 tgctataatt ctaaataaag gataaggatt ggaaataatc cttttatcat taaaaatatg
     2101 atgacgaagt agaataaaat tgggagtagg ggggaaagtc atggatatcc aaactgtttt
     2161 atctgatctg aaattaaatg gtaaagtgat tccagttgtt ggtggcgatg ttaatcagac
     2221 ctatcgtata aaaaccgaac atcgtgctta ttttttaaaa atccatccga atgtaaaaaa
     2281 aggatttttt gaagcagaag tagacggatt aaaagaactg tcagcattcg tacgtgtacc
     2341 ggatacgtat atgctaggtg aaacaagtga aggcgcttat ttgttaatgg aatggatcga
     2401 gccgggaaaa ggggatcaac gagatcttgc tgcagcttta gctaatctcc atcagcaaac
     2461 agcgccacaa tttggttttc gtaaagataa ctatttgggt acacttgttc agaaaaattc
     2521 ttttgaagaa gattggtgga cttttttctt taaagatcgg cttgaatccc agatttcttt
     2581 ggcagaagaa acgaatcgat ggaatgtaca gcgtcaagaa aagtatctgc gatttaaaga
     2641 acgtgtattg aaatcggttg aaccaaaaaa gatcactcca cgcctcttgc acggagacct
     2701 gtggagtggt aatgtgttct ttgaccagca agggcatcca gtttttgtcg acccagctgt
     2761 ttcttatggg aatcgggaac aagatattgc aatgagccag ttattcggtg gtttccgacc
     2821 ggaattttta gatgcttatc aaactatatt tccattagaa aagggatgga aagaccgact
     2881 gccgatttac cagttatatt atcttttggc acatttgaat atgtttggag aaagttacgg
     2941 ttcccaagta gatcaattac tagaaaattt ttaagaggag ggcgtgtttt tggcaaaaaa
     3001 atataccaaa aagcatgaag tttcatatta tgagtgtgac atcaaccaaa cgatgacatt
     3061 tccttcgatg ttaggagtag ttatcaaaac gtctgaagat caaagcgacc agttgggaag
     3121 aggcagtgaa ttcgtcaata gctttggact tacttgggtc atcacgaatt attccatgga
     3181 gattaatcgt ctccctagag tcggtgaagt aatctcagta acgactcaag ccatggagta
     3241 caataagttt ttctgttatc ggaacttctg gatccatgat gaagatggga aagaattagt
     3301 caaaatagaa tctgttttcg tattgatgga ttttgtgaat cgaaaaatga gcagtgttaa
     3361 tgaagagatc attgctcctt ttgagagtga gaagatcaag aaaatcaagc gtcaggaaaa
     3421 aattgaaaag attgattcgg gcttcatgtt gccatatcgt gttcgttttt atgatatcga
     3481 tagtaatcag catgttaata atgcgatgta ttttaattgg atcattgacg tattaggata
     3541 tgactttttg actacgcatg ttccagaaaa agtaattatt cgatttgata aagaagtaga
     3601 gtacgggaat gagatcgaaa gccattttga acaaatccct atcgaaaatg gtgtcaaaac
     3661 aaaacatgaa atccgaatgc aagaacagct gtattgtgaa gcaaatatta tatggaaaaa
     3721 taaataaaaa agaggttgtg acagaagggg gcaacttcaa gaaataagaa gaaatttacg
     3781 aaaattgttt ctcaaatttt tgtaaatttt cgacttagtt ttcgaagaag ctatttttgt
     3841 cacagcctct ctttttaagt ttagctatta gataatgatg tttagttttg gataaacgaa
     3901 atcaattctt cacccgacaa accatagttt acagcaatca atagttttaa acgtgctttt
     3961 tgactattaa tactgttaca gaaaataatc cccatttttt ctagttcttt tcccccgcct
     4021 tcataatcat aaacaggctc tgcgattcca ttgaaacaac gagaaacaag tactacaggg
     4081 attttttgga caagaagctt ttccaaagca gctaaggctt gtggagggag attccccgca
     4141 cctaaagctt cgattaccaa accgtctact ttcgtatggg cgatggcttc caataagtcc
     4201 ccttgcatcc cagcatatgc tttaacgatc gggatagtcc catctacagc ggaaatgtcc
     4261 agtcgctttg tttctaaaag ttcctgcaag aataaaattc gattcttagt tactaagccg
     4321 atgggaccca atgtaggtgt tcggaaagta gcaacatttg tggtatgggt ctttgtcacg
     4381 tagcgtgcag aatggatctc atcgttcatg accaccaaaa cccccttatc tagcgcttct
     4441 tcacaacttg cgacacgaat cgcactttca aaattataaa ggccgtcact tccaagttca
     4501 ttacttgaac gcattgcccc agtcaaaaca attggtaatt tgttgccaat cgttgtatca
     4561 agaaaaaaag cagtttcttc taatgtatct gtaccgtgtg tgatcaccac tccggatata
     4621 cctgatgcat aagcggacaa gatacgttct tttaatacca acatgtgaga aggcatgatg
     4681 tgtggtgagg gaagattgaa gatatcttca actaataatt ctacatgctt ggggattgtg
     4741 atttctgcat ctaataatgg gtttgccaca tcaggactaa caccgcccgt gagcatgttt
     4801 tctttcatgg cgatcgttcc gccggtgtgt agtacaagta tttttttcat tttacagact
     4861 tccttacgaa taattttgca tagccgttaa atcttattgt atactatata aaagagtttt
     4921 gctatcagtg aagaataacg aatagcctaa cttatcataa aaaagctgac cttattaaaa
     4981 tggaaaagac tcaaccttga cctcctaata caatggagta tctggttgag tttcttttac
     5041 aagaaagcag ccaaggaaat caatcacgaa ggtggccgga aatgatcaga atcggattaa
     5101 catcgtttaa agaacatgac aaattaactg gtaaaaagaa taacactctt tatgaatatg
     5161 cagggtttct acccttagtg gaattagata ctgcctatta tggaattccc cgaaagtcct
     5221 cagttgagaa ttggataagt gaagtacctg aatcatttcg ctttgtagtc aaagtctatc
     5281 aaggaatcag cggtcaagga gactggaagc cttattatca gaccgaagaa gagatgattg
     5341 cgcatttttt agatgttatg tcgccaatgg tagatgctgg aaagatgttt tgctttttag
     5401 tccaattccc ctcatcattc aaatgtacga aagaaaatgt ccagtacttg cgcaaactta
     5461 gaaagtggtt tgagggttat cctgtttcta tagaattgcg ggattattct tggtacagcg
     5521 atgaatttct tgaacgtaca agaaacttta tgtctagagc cgctttttct ttagccatca
     5581 tcgatgagcc acagttgctg aatacaacga ttccttttga tccatttgtc accaatccga
     5641 actttgctct ttttcgattc catggtagga atgcgcaagg atggcaagca aatgataaag
     5701 agtggcgtaa aaaaagaacg ttatatcgtt attcagaaaa agaactgcaa gaactagcac
     5761 atgaagtcaa agtagttgat tctaagacaa aagaggtagg tgtgattttt aataataatt
     5821 ctggtggtga tgcggctgaa aatgcattag cactgcaaaa aatattaaat atcaagccag
     5881 atggactcaa tccaacccaa atggatctgt tttaagggct tattttattc aagaaagggg
     5941 cgaagtctat gatcaaagct attttttttg atattgacgg aacattggtc accaatcgtt
     6001 caaaagcgtt ggaatcaaca aaacaagcaa ttgaatatgc tcggaaaaac ggcattttat
     6061 gcggtgtagc aacggggcgc agcccagtaa agatcaaaga aatcattgat gaattggaat
     6121 tagatatgta tgtcgtgtat aatggtcaac tggtttttac tgcagatcgc acgattatcg
     6181 accacccttt tgaacaaaaa gtattggaac atattgttga atttgcagat gagaaccatc
     6241 gacaaatcgt ttttggtgcg agaaatcggt tagatggatc aacgacgatg ctattaggac
     6301 aatcgatttt tatcaagcga ctagtcagct ttttaccgcg taaattcccg gtacgtctga
     6361 tgaaaaaaat cctccaggtt tttagccctc accgacaaaa ggatcgttat gaaacgttag
     6421 agatattaaa agaaccaatt tatcaatgta tattgctcag tccggagtca gaacagaaaa
     6481 agttagaaca tcgctttccc gagtgtacgt ttcagcgttc aaatacgtat actgtagata
     6541 tcatcccaaa aggtggttca aaattactag gcatccaagc tttcgcaaat gctgtcgaaa
     6601 ttgaaatgga agaaattatg gcattcggcg atcattacaa tgatatcgag atgctgaaag
     6661 gtgtaggaat tggagtggcc atggggaatg ctcagatcga agtaaaacat gctgcagact
     6721 ttgtgactca atcaaatgaa gaagatggga tatacgaagg actgaaacac ttcggtctga
     6781 tttattagtc aatgaaagaa ggaaaaaatc agtatggaag cagagacacc ttttcaaaaa
     6841 gtagaaacat tccacaaaac ttttgatcca agaagaccag agatacccac ggcttttaca
     6901 gaaaatgaag ctcatacacg tgctgcgttc aaaatagaag aacttgttga atttgttgca
     6961 gctacttcac ctaataaaga acaactgcat gaagctgtta tgctgctgca cgaagcatta
     7021 gataaagcag aagaaaaaat acttggtaaa acacagtggg gaagtgatcc gctggttgaa
     7081 caagtagatg cactgacaga tatcctttac tttacttatg gttctttttc attactagga
     7141 atagtgcctg atcgaatatt cgaaatcgtc catcaggcaa atatggggaa attatttcca
     7201 gatggaaaac ctcattatga ccctgtaaca aataaagtgt tgaaacctga aaactggcag
     7261 atggaatatg ctccagaacc taaaatcgcg gcagaaatcc aacgtcagat tcaagaagcg
     7321 attgctaaga agaaatccgc tgatataggc atgtgcacaa atgaaaaaga gtgatcagag
     7381 tttcactatt tttgttatct ttatacgatg gaaaaacaaa agattttcgt ttaagttagt
     7441 gaatgcatga aaatagtatg ctataatcta gaatagatgt cttttgcacg agagacgtat
     7501 tatttggatt tatgccaagc agaacgccat ctgttgcata aaagatgcat actgaaaacg
     7561 gaggaaccat aaatgggaaa taatgttatc atcggaatcg tcattgcaat cattatagtc
     7621 gccattgtcg tctttttggt tagttacttg atgaagaaaa aaaaccaaga tcgattggat
     7681 gccttagaaa aacgcaagga agaattattt gacttgccag tgattgaaga agtcgatgat
     7741 gttaaaaaaa tgcatctggt tgggcaaagc caaaatacct ttcgtgaatg gagtcaaaaa
     7801 tggaatgaca tatctacttc ctcgttcgct gaactagaaa gtcaaatttt cgaagtggaa
     7861 aacctcaatg aaagttttcg gttcttaaaa ggaaaaaaag cagttgttga agcagaagct
     7921 acaatggacc aaatggagaa acaagtgacg gaaatccgtg aaggtctaaa ggaattgcgg
     7981 gaaacggaag aacgcaactc actagctgtt cagcaggcac ttgacgtcta tgaagaactg
     8041 aaagaaaaag tcagagaaga cgagcatgaa tacggaccag ctctttttga attgcaaaaa
     8101 cagatcaaag tgatcgaaaa agaatttacg cagtttgtga ctttaaacac ttctggagac
     8161 cctgttgaag cccgcgaggt tttggataaa gcagaaaaac atacgtatga agtggaagct
     8221 ctgatgaaaa aaattccacc gctgtatgag gagctccata ccactttccc tgaacaactt
     8281 gaagaaatca gtgatactta cgagaaattg atggaagaac aatatgtatt cccagaagaa
     8341 gatcttgctg aagatatcgc aaaagtaagt cgaagaattg aaaattcatt agccaatctt
     8401 gaaaaaacag aagttgaaac ggtcgaattt gaaaaccgtg aaacagctga tttgattgat
     8461 tcgttatatg atatcttaga acgggaaatg gaagctcaga gatatgtaaa aactaaccaa
     8521 tcaacgattg cagagtatat caaacataca acaaagaata accgtcaatt attgattgag
     8581 ctggatcaca catctcaaag ctatacattg aaccacaatg aaattggccg tgtacgaggt
     8641 ttccaaaccg aagtggaaga aatggaacgt caaaatgaac agatgattcc acagatccgt
     8701 caacacgaaa ttccttattc agaagtgcgc acgttctata aaacagtctt caaagtctta
     8761 gaagatatcg aaaagcaaca agtagagatc gacgactcat tacatgaatt gagaaaaggc
     8821 gaaaaagaag cgcaagaaaa gatcgataca ttcgaattca aattgcgcag tttgaaacgt
     8881 tttgtagaaa aacaacgttt gcctggcttg ccgaatgatt acctagaatt cttttttgtt
     8941 gctactgacc gtattgaaga actaagtgtt gtcttgaata aaattcgagt aaacatggaa
     9001 gaggtcaatc gtttagttgc tctatgtgaa gaagatctag aattattaga taagaagaca
     9061 catgatttag tagatgcagc agcattaacg gagcaaatgc tccaatatgc aaatcgttat
     9121 cgtcatacac acgaagaagt gagagaagca attgataaaa gctactattt attcaataaa
     9181 gaatatcact atcaagaagc attagacgaa atcggtacag cattagagcg agtagaacct
     9241 ggtgctttca aacgcatcga agatttttat tttaatcatc cagacttagt ataaagcaaa
     9301 aaagttagta aaccagcaag agcaagacgg attattgtct tgttcttgtc tttttttgta
     9361 tatttgaaaa ttgaaacaag tgaaaatttc acctgctctt gaaagcacct tggacaaccg
     9421 ttataataga aaagaatttc aaaaaagagg ggtttcttat gatatatttt gataacagtg
     9481 caacaacccc aatctttccg caaagcttag atgcatatgt aaaaaccagt cagcggatta
     9541 ttgggaatcc atcaagcttg catgatttag gcaatcaagc taaccggttg ttgcagcaag
     9601 caagaaagca gatcgctgat ttgatccatg tagaaccaga agaaatctat tttacttcag
     9661 gcggaacaga aggagataac tgggtattaa aaggaacgat gatcgaaaaa agagaatatg
     9721 ggaatcatat gatcatttca ggagtcgaac atccggccgt cagcgagaca gcagaacaat
     9781 taaaagaatt aggaatcgaa gtaagtatcg ccccagtgga taaacgcgga tttgtacgtg
     9841 tcgacgaatt gaaagaatta ataagaaaag agacagtatt agtctctgtt atggctgtga
     9901 ataatgaagt aggatcgatt cagcccatcc aggaaatcag tgatcttttg gatgattttc
     9961 ctaaaattca tttccatgta gatgctgttc aggcgattgg aaaagtacca ttctcgcaat
    10021 ggttgacaga aagagttgat tttgcaacat tttcagctca taaattccat ggcccacggg
    10081 gaactggttt catttattgg aaaaagggtc gtcgtttagc accattactg acaggtggag
    10141 ggcaagaaag aaatcagcga agtgggacag aaaatgttcc aggtattgtg gctatggtta
    10201 aagctttacg tttatcatta gagataaagg aacaaaaacc tgagcagaca caacgcttaa
    10261 aagtagctct aatcaatgcg ttgaagacgt atgagaaagt gacgattttt tcagaaggaa
    10321 ctgactatgc accgcatatt ttatgttttg ctctaaaagg aattcgcggc gaagttctcg
    10381 tccatgcctt agaagaaaaa caaatatttg tttctactac tagtgcctgc tcctcacgta
    10441 aacatatggc aagcagtaca ttgcacgcaa tgcatgtacc aaatgatctg gctacatctg
    10501 ctgttcgaat cagcttagat gaaaacaatt cgcttgcaga agtcgagcaa tttatgatta
    10561 ttttcaagca gctttataag aaattttctg caatcaatta aaagaggagt gttcttgtga
    10621 aatacagtga aattatggtc cgttatgggg aactttcgac aaaaggaaag aatcgaaaaa
    10681 gctttatcat gcaactagca caaaatgtca gacaagcttt gaaagacttt ccagaaatca
    10741 aaatccatgc tgatcgggac cggatgcatc ttttattgaa tggcgcagac gggcagctag
    10801 ttattccaaa actagcaaaa atatttggga tccaaaattt ctctccaagt attcgtgtag
    10861 aaaaagatgt cgaagttttg aaacaagctg ttcaagacat catgaaagaa atttatactg
    10921 ggaaagaaac atttaaaatt atcgctaaaa gaagcgatca ccaatttgaa ttgacaagta
    10981 atgaattgaa tcaaacatta ggtaatgctg tttttgatat tttcccgcat atccaagttc
    11041 aaatgcgtca accagatatt ccattacgtg tagagattcg gcgtgatggc gcttatctat
    11101 cgtatgaaac gatcaaggga gctggaggat tgcccgtagg aacaagcgga aaaggaatgc
    11161 ttatgctttc tggggggatt gattctcctg tagcagggta ctttgccatg aagcggggag
    11221 tggaaattga agctgttcat tttgctagtc cgccgtatac aagtgaacaa gcactgcaaa
    11281 aagcaaaaga tctaacagcc aaactagcac cttatgtggg aacgatccat tttatcgaag
    11341 tgccatttac cgagattcaa gaagaaatca aaaagtcagt gccacaagga tattggatga
    11401 caattactcg tcgaatgatg ttgcgtttga ccgatgaaat tcgccgtatt cgtcatggtt
    11461 tagtcatttt gaatggtgaa tcattaggtc aagtggcttc acaaactttg caaagtatgg
    11521 tggctatcaa tgaagtaacg aatacgccaa tcattcggcc tgtagcgaca atggataaac
    11581 ttgaaatcat tgaagtagca gaacagatcg atacatttaa tctttctatc cagccttttg
    11641 aagattgctg tacgattttt gctcctccac agccaaaaac acgccctcaa ctggaaaagg
    11701 tccatcaata tgaagagcgt ttagcaatag atgaaatgat ccaacgagca ctagctggct
    11761 tgaagatgga agagatacaa gcagaatcgt ctaatgaaaa aactgaagaa ttttcagaat
    11821 tgctataaga ggttatgaaa atagtgtttt gaccagagta ttagagaaac aaaacgaaaa
    11881 aatagctcca tgtattttac cgtttttgaa ctaatgtcga agattagctg attgaatacc
    11941 atttatcaag aagttatgga aaagccggtt cttttttact aactgaaaaa taaaatttta
    12001 tttagagatc aagctacagt tgataaatga tataaaaaag agaatttccc atgaaatagc
    12061 gaggttgtga cagaagtggg cagcttcaag aaataagaag gaatttacga aaattgcttt
    12121 tcaaattttt gtgaaatttc ggcttatttt tcgaagaagt tacttctgga acaccgtgta
    12181 tcagaggttg cgaaaaagct gccctgcatc aagtaataag aacagccaaa caaaaatagt
    12241 tcctcatatt ttacgtttgg ttgagcttat taccgcagat gcaagctttt gaacaccgtt
    12301 ttatttgtct cacacccttt tccttcctac ttgtaacctt gctcccgtgt tagaaacatg
    12361 ttacactaaa tatgtgaaat tattaacaag gagcgtcgtt atgcgagaaa aaacagatac
    12421 actgccaaaa gcaactgcga aaagattacc tttatattta cgctacttga agttgctgga
    12481 tgactcaggt ataagtagaa tcaaatcaaa tgagttcagc gaaatcaccc aaattccttc
    12541 tgcaacgatc cgcagagact tctcgcaatt aggcgagcta ggcagaagcg gatatggcta
    12601 tgatgtccct tttcttatcg atgtattcaa taatatcctt aatactaaag aagaaaaacg
    12661 aatcgcatta gtaggatatg gaaatcttgg caaagcattg aaacacaaca attttagaag
    12721 aaatgaaaat ctaaatatcg tgtgcgtctt tgataatgat ccagcactga tcaatcgagt
    12781 aattgatgga gaaatgatct atccgattga tcgtttcgcg gagatagcca aagcaaaaaa
    12841 tgtgacagta gcaatctcta cggtaccaag taaatattca caatctgcta ttgatgaaat
    12901 tgtcaaagga aatgtaaccg ctatacttaa ttttgcgcct gacagagtaa ctgtcccagc
    12961 ttatgtcaat gttcaataca ttgatttgac aaccgagttg cagacgctta tttactttga
    13021 tgagaattac tcagaagttt tttcttagga aaatttgagt aggcttattg atcttgcgag
    13081 aactcgtcgt aattctttca aaaatttttt agtactaaat gaagtggttt tttcacgacc
    13141 acttgttgac taaaaaaaaa aaccattgta gaatgaagca taacgctgaa caagaggagt
    13201 aactggcaca ttcattctta gagagagaac tatctgctga aaggttctca atgacaacca
    13261 gtgaaggtag cttgggagtt tctgtcttga atggagtaga gatagacgag tcgtgatcgt
    13321 taactcactt gagaggcaat aatgattgat tattgcaatt taggtggtac cgcgtaaatc
    13381 atacgtccta gaatacgaaa gtattttagg acgtttttta gtttaaagga ggaaaacagc
    13441 atgacggaag aaaataacct atcaacaaaa tataatccgc aagaagttga agctggacgt
    13501 tatcagcatt ggttagaaca agatttgttt aaaccgagcg gagataaaaa agcaaaacct
    13561 tattcaatcg taatcccgcc cccaaatgtt actggaaaac ttcatttagg gcatgcttgg
    13621 gatacgacct tgcaagatat gctgattcgt caaaagagaa tgcaaggata tgatacttta
    13681 tggctgcctg gtatggacca tgcaggaatc gcgacacaag caaaagtaga agcgaagctt
    13741 agagagcaag ggatttctcg ttatgatcta ggtcgtgaaa agttcatcga tcaagtgtgg
    13801 gaatggaaag aagagtatgc gagccacatc cgcgaacagt gggctaaaat gggcttatct
    13861 ttagattaca gtagggaacg ttttacatta gatgatggat tatctgaagc agtacgtaaa
    13921 gtttttgtta ccttatacga aaaaggtttg atttatcgtg gtgaatatat catcaactgg
    13981 gatcctcaag cacgaacagc tctatctgat atcgaagtta ttcataaaga tatcgaaggc
    14041 gccttttatc atatgagcta tgaactagca gatggatcag gcgtagtaga aattgcgaca
    14101 acccgtccag aaacgatgtt gggagatacg gcgattgctg ttcatccaga agacgagcgt
    14161 tatcaagcgc tcatcggcaa aaaagtgatt ctacctttag tcaataaaca aatcccaatc
    14221 attgcagatg aatatgtaga tatggaattc gggacaggtg tagtaaaaat cactccagca
    14281 catgatccaa acgactttga ggtaggtaat cgtcatgatc ttccacgcgt aaatgttatg
    14341 gatgatgatg gtacgatgaa tgaactagca ggaaaatatg ctggaatgga acgttttgct
    14401 gctcgtaaag caatcgtgca agatctgaaa gaaatcggtc gattgattaa aatcgatacg
    14461 atgatccaca gtgtgggtca ttccgagcgg acaggtgtcg ttgttgaacc tcggctgtct
    14521 actcaatggt ttgtaaaaat ggcgccgtta gcgaaaaaag ccattgataa ccaagaaaca
    14581 gatcaagcag tggaattctt ccctccaaga ttcaatcaaa cgtttttacg ttggatggaa
    14641 aatgtccatg attgggtaat ctcacgacaa ttatggtggg gacatcaaat tcctgcatgg
    14701 tatcacaaag aaacaggtga aatgtatgta gggatggaag caccagcgga tagtgaaaac
    14761 tgggtacaag atcctgatgt tttagacact tggtttagtt cagctttgtg gcctttctca
    14821 acaatgggct ggccagatac ggaaagcgaa gattataagc gatacttccc tactagcact
    14881 ttagtaaccg gttatgacat cattttcttc tgggtaagca gaatgatttt ccaaagcttg
    14941 gaatttactg gcgaacgtcc atttgagaat gtcttgattc atggattgat tcgtgacgaa
    15001 caagggcgga agatgagtaa atcattaggt aatggaatcg atccgatgga agtaatcgaa
    15061 aagtatggag cagatgctct ccgctggttc ttatcgaatg gttctgcacc aggacaagat
    15121 gtccgcttca gctatgaaaa aatggatgct tcttggaact ttatcaacaa aatctggaat
    15181 gcttcacgtt tcgttatcat gaatatcgaa ggaatgaccg tagaagagat cgatttatct
    15241 ggagaaaaat cagtggctga ccggtggatc cttactcgtt tgaatgaaac gatcgaacga
    15301 gtaactgagc tatttgatcg ttttgaattt ggtgaagcag gtcgacaact gtataacttt
    15361 atctgggatg atttttgtga ctggtacatc gaaatgagta aagaagtact ttatggagat
    15421 gatgctgttt caaaacaaac cacccgtagc atcttagtcc atacacttga tcagatccta
    15481 cgtttattgc atccaatcat gccattcgtt acagaagaaa tatgggaaca tattcctcat
    15541 cagggaaatt ctctagtagt ggcagaatat cctgttgtac gtccagagtt tgatgatgaa
    15601 acagcttcta aagggatgga agtattgaaa gaattgattc gagccgttcg aaatattcgt
    15661 tcagaagtga atacaccatt gtctaaacca attacgttgc taattaaaac aaacgatgct
    15721 aaaatcgatc aatttttagt tgaaaataca agctatatcg aacgcttctg taatcccgaa
    15781 gagttgacga tatcaagtga gatcactgcg ccagatctag cgatgtcagc tgttctgaca
    15841 ggtgcagaaa tcttcttgcc gttagcagga ttgatcaata ttgaagaaga aatcaaacga
    15901 ttagaaaaag aactggaaaa gtggacaagc gaagtaaaac gtgtccaagg aaaactttct
    15961 aatgaacgtt ttgtttctaa cgcgccggaa gaagtagtag aggcagagcg tgcaaaagaa
    16021 aaagattatt tagagaagca aacggctgtc aaagaacgaa tcgaaagttt gcgtactatt
    16081 caataagaat agaaaaagag agtgtgaaat cagctagcta ttactaaaag ctagctgatt
    16141 gaacatcgtt acaggaaaga gtttgagcct cactcttagc ttcgattcat aaggagatgt
    16201 gacataaatt ttgtcgcatc tcttttttag tctactctta ttatgtagga gaaggaggga
    16261 ggtggatcat gtatcaagag tcaataaagt agttgataaa atcgttcctc tctctgtttc
    16321 ttttctcttt gtcatacttt tatttttctt atgtgttcta tttgttataa taaaagagaa
    16381 atgggggaat tgttgatgac gattgaagaa gcaatagaat ggatccatag tcgattacca
    16441 tttggttcac gtcctggcct tgaccgagtc gaagctttat tagaagtggt agggcatcca
    16501 gagagaaaag taaaaacgat ccatatcgct ggaacaaacg gaaaaggttc tactgtagct
    16561 tatttgagaa gcctattaga agaggctggg ctgacagtag gtacatttac ttcaccttat
    16621 atcgaaacgt tcaatgaacg gatcgcaatc aatggcaaaa gcattccaga caatgatttg
    16681 atccagcttg taaaaaaata tcagccactg atcaaacaac ttgatcaatt tgaagcagta
    16741 gctggtatta ctgaattcga gacattaaca gcaatggcat ttgattattt tttgatgaag
    16801 aaagtggacg tagcgattat cgaagttggc ttaggcggct tattggattc taccaatgta
    16861 gctgtaccaa tgctgacggg aataacaacg attggacttg atcataccga aatacttgga
    16921 gatacaattg aagaaatcgc tgcacaaaaa gctggaatca tcaaacaagg cgttccagta
    16981 gtaacaggaa atattgcccc agaagctttt actgtcatcc aacaaacagc taaagcaaaa
    17041 aatgcaccgc tttatgtata cggggaaaat tataaaataa actatctgca tcctgatgag
    17101 atgtggggag aagtatttga attttttaat gaaataggaa agatccctca attaaccact
    17161 ccgcttttag ggcaacatca agctgaaaat gcaggagtag ccatcgaatt gtattttgtt
    17221 tactgtcaat tggaaaagct gcctttccga gaaaaagatg ttttgaaggg attgaagaaa
    17281 tctcgatggc caggaagaat ggagcgtttg agtaacgagc cattagttgt tttagatggt
    17341 gcccataata cgcatgcaat gaaccggctt gttgagaatt tgaaaaaaga attcaaagga
    17401 tatcaaatca acattttgtt ttccgcctta cgaactaaaa atgttagaga aatgctagaa
    17461 cgattgcagc aagtaccaaa tgtccatatt tatttgacga cctttgaaca tccaaaagcc
    17521 atcgaattaa gtgaagtatc agatttagca agtgagagag tatcaatcgt ttcattgtgg
    17581 caattcggat tagcagatat attggaaaag atgacaaatg aagacgtatt agttgtgacc
    17641 ggttcacttt atttcatttc agaagttcgc catttattaa tacaattagg aggagatcat
    17701 gaagtataat gcagtgattt ttgacatgga tggtttgctg ttcgacacag agttagtgta
    17761 ttacgaagcc acacaagtag tagcagacaa gatgggtttt ccttatgata aagacctgta
    17821 tttaaaattc ttaggtgttt cagatgaaga agtatgggcg aattatcata tgattttctc
    17881 ggaatttggc aaaacaagtg tacaaagatt catagatgat tcataccagg aaacgcttga
    17941 acgtttttcg caaggagcgg tacaaatgaa gcccggtgtg ttggaactcc tctctttttt
    18001 agaagaacat cagattccca aagttgtcgc ttccagtaac caacgagcag tcattgaact
    18061 tttattgaag aagaacaatc tgtttgaacg atttgagacg attgtttctg cagaaaatgt
    18121 tcaacgagca aaaccagacc cagaaatttt cttgttagct aatcagaagc taggtacagc
    18181 gaagaaagaa acattgattt tagaagattc acaaaatggt attttagcag cttctgcggc
    18241 tgagatcccg gtagtcatgg taccagatct gcttccacca tcccaagaat tgatcaaaaa
    18301 aacagctggg gttgtttctt ctttacatga aatccctgca ttgttaaaat aaaaatccat
    18361 ctcttttcgt atcttatttt agataagata gaaaggagat gtttttttgg gaaaacgatt
    18421 gatcaaagaa gtacctacta gctctttacc aagggaacgt atggaaattt atggcgcgga
    18481 agctttatcg gatcaggagc ttttggcaat cttactgcgt accggtcaac acccttatag
    18541 tgtgatgtcg attgctggaa atctgttaaa aacgtttgga ggactggcct ctttacgaca
    18601 ggctactttg catgagttag aagagattcg agggatagga cgcgtgaaag caatcgaaat
    18661 caaagccttg atcgaattag gtcgacgaat tcagacggat catgaaagag cggctccacc
    18721 ggttcgtacc agctacgaat tggcccagca attgattctg gaaatgaaag atcacaaaca
    18781 agaacatttg gtttgtattt atttggacac gaagaatcaa gtgatcttaa aaaaaacagt
    18841 gttcatcggt tcgctgaatc agtcagtcgc tcatcctaga gaaattttcc attatgctgt
    18901 acgttattgt gcagcaagga tcgttttagc gcataatcat ccttctggta atgttattcc
    18961 atcgcagcag gatatgaatt ttaccaaaag gatacaaaag tgtggagaaa tgatggggat
    19021 cactgtactg gaccacttga tcatcggacg caaacgatat tttagtttga gagaagaagg
    19081 aatgatggaa gagaagtaag ttgctttctt gcaaaaaaaa tgaagcaagt gtacaattat
    19141 attgtaattt tgtttgggaa tagaagttga aacatctgtt gcacctctat cgtacacgag
    19201 caatgttaca atttaaatta gtgcttttgg cacgaggagg atattattat ggaaaacgga
    19261 acagtaaaat ggttcaacgc tgaaaaagga tttggattta tctcacgtga agatggaagc
    19321 gacgtattcg ttcacttctc agctatccaa ggtgacggat tcaaaacatt agaagaaggt
    19381 caagcagtga ctttcgacgt tgaagaatca gaccgcggcc cacaagctgc aaacgttgta
    19441 aaagcttaat tttatctgta aatcaaattg atggtagaca tcaattttta cgagagaaca
    19501 aagcgagtaa caaaaatacc tgccacaaga gacaatttct cttgtggcag gtattttttt
    19561 gtatgaaaaa gtaaataaat ttaagaggct atgaaagagc caccttgtat caaggaataa
    19621 gaacaaacaa aaatggcttc tcatgttttt catttgtttt ctcttatatt caggacaagg
    19681 tgctgatttc ataacctctt atttattctt catctggtgt cattaccatt ggcaaaatca
    19741 ttggatgtct ttctgtacgt tcgaataaga aaggctgaag cgcgccagtc atcgcttctt
    19801 tcaatttata ttctgaacag tcaggtccat tcaaacattc tcttaaagcg tggaataaga
    19861 ttcgctgagc ttcattgatc atttctcctg attctcgcat gtagacaaat ccacgagaga
    19921 gaatatctgg accagccaag atttcttttt tcttgatatc cactgtcgcg acagctaata
    19981 caagaccttc ttctgaaagc aggtgacggt cacgtaaaac gacattacca atatcaccga
    20041 tcccgctacc atcgatatac acatctccag ccacaaaatg cccagcagga cgcgcagaat
    20101 cgctagttaa cgctaaaaca tcgccatttt ccatgatgaa gcagttttct gcaggaacac
    20161 ctacatcttg tgctagagaa gcatgtactt tcaacatgcg gaattctccg tggacaggaa
    20221 taaaatattt tggcttcatc aaacgaagca ttaatttttg ttcttcttgt ccaccgtgac
    20281 cggaagtatg gatgttattg atttttccgt gaatcacttc tgcaccagct tcagacagca
    20341 aattgatcaa atgattgaca cttgttgtat taccaggaat aggtgaactt gaaaagatca
    20401 ctgtatcgtc tggctggatt tggatttgac ggtgagtacc attcgcgatg cggctcaacg
    20461 cggccatcgc ttctccttga gaacctgtac ataggatcat cgtttcattg gcaggcaagc
    20521 gattgatttc gtgtgcatct acaaatgtgc cgtctggaac tttgatatat cctaaacgtt
    20581 gaccgttgac gatggcattt tccatgcttc gtccgaaaac agcgatttta cgaccagttg
    20641 ccacagcggc atctgctgct tgctgcaaac ggaagatgtt agaagcaaag ctggcaaaaa
    20701 tgatacgtcc ttcgattttt gaaaagatct tcaaaataga atgcccaatc gttttttctg
    20761 atttagtaaa tgttggaatc tcagcatttg tactatcaga taaaaggcac aagactcctt
    20821 cttccccgat acgagccatt ttatgcaagt ttgctggttc gccaacagga gtgaaatcga
    20881 atttgaagtc tccagtcgct acgatatttc cagaaggtgt tttcaccacg atccctaatg
    20941 catctgggat actatgggtc gttctgaaaa agctgacaga agtctttcta aaacggatga
    21001 tcgtatcttc attgatctca tggagctctg catctcgaag caagccatgc tcatctaatt
    21061 tgtttgtgat caacgctaat gcgagaggac cagcatagat aggaatattt gcttgtttca
    21121 gcaagtaggg tattccgccg atgtggtctt cgtgcccgtg agtaatcacc aaggctttta
    21181 ctttgtgtaa gttttgtatg atgtagctgt agtcgggaat gacatagtca attccaagta
    21241 aatcgtcttc cgggaatttg atcccggcat caatcaaaat gatttcatct tggaattgta
    21301 ccccatacgt atttttcccg atttcaccta atccaccaat agcaaagacg cctgtctcgt
    21361 tatttttgat ggaaagtttc atattaaaac tccactaatg agaaatcagc attttctttt
    21421 tcgtactcta gatgacttcc ttctagaagt tgaacgaatt caatattgta tggggtattt
    21481 tcttccacac gttggcgagc gtctacatcg ctttttgcct caatgtaaag agattttgtt
    21541 tcttcccgtt tagggttgcg tacttttgtt tcttgataat aaactttata gatcattgtt
    21601 ttgtctcctt tatctgcgta aagcagtgat ttagctagtt gattttttta gacaacacaa
    21661 aacgagggga caagccacct ggtttttcat atgctttgac tagaatactg gattcgagtc
    21721 aaagagacaa gcctcgtttt tgcttatctg ttcggatatt ttttcaaccg taccttctgt
    21781 ataaaaaata tacaacaatt aattgttatt ctagcataaa acagcaaata agtatagaaa
    21841 tcaactagat tgaaagaaaa aatcaatgtt tatcatcccg ctataatcat aatgactttt
    21901 ttatgagaga agtgttctat taataggctc gttgtgctat catttttagt aatgaaaatg
    21961 taacaaaaga ttaaaaggag atgagaaagt gaaactaatg tggcattata ccatgcgtta
    22021 taagaaattc ttgtttttca atttcatatg cgtatttggt tttattttga ttgaattagg
    22081 acttcctacg attttagcac gtatgatcga tgtaggaatc cgcaatgatg attttgatta
    22141 tgtgaagcaa caagggatat ttatgatcgt tattactgta atcggtatta ttttgaatat
    22201 cttgttaggt tattttggtt cgaggattac gactaatatc gtagcagata ttcgagatga
    22261 tttgttcgaa aagatccaaa gttattcgca tcaggaatac gaaaatctag gcgtatcttc
    22321 attgatcact cgtacaacaa acgatgctta tcagatcatg ttgttcctgc aaaatatttt
    22381 acgtatcggt tttatggcac caatgatgtt cattgtcagt ttgtacatgg tcatgcgtac
    22441 aagtgtgaca ctcagtttgt atgtagtagg tgcattacct ttactattat tggcagtcgt
    22501 agcgattgct aaggtgtctg aaccgttatc taaaaagcaa caaaaaaact tagataaaat
    22561 caacagtatc ttgcgggaaa atctttcagg attgcgtgtg attcgtgcat tcgtcaatga
    22621 aaagtttgaa gaaaaacgtt ttgctgtagt caatgagaat tatgcttcta gttcaaaaag
    22681 cttattccgt ttgatggctg ttgcacaacc gggtttttat ttcttattta atatcgtaat
    22741 ggtattgatc atctggagcg gggcagtgca aatcgatgca ggcgagcttc gtgtaggaga
    22801 tttgattgcg tttatcgagt atatattcca tgccttgttc tcattcatgt tatttgctag
    22861 tgtgttcatg atgtatccaa gagcagctgt ttcagctgga cgtatccaag aagccctaga
    22921 tgccaaacct tcgattgtag aagatccaaa tggtatatct gatacaaaaa ctaaagggta
    22981 tatcgaattt caaaatgtaa catttgctta tccaggccat tcgcaagagc cagtgatacg
    23041 aaatgtcagt tttacagcct ctccaggaga gaccgttgct tttattggaa gtaccggtag
    23101 cggaaaatct acgttgatcc aattgatccc tcgcttttat gatgtgagtg aaggaaagat
    23161 cttgatcgat ggagtagacg tgagagatta tcggctaagc aagttgcgag ataagattgg
    23221 gtttattccg caaaaagcgc tgctatttac tggaacgatt gcagataatt tgcgatacgg
    23281 gaaagaagat gctacgcaag aagaaatgga acgtgcagct gagattgctc aagcttcaga
    23341 attcatttct cgaaaaccag atggatttaa tgaacattta tcagaaggtg gttccaattt
    23401 ttcaggtgga caaaaacaac gattggcaat agccagagcc atcatacgcc gtccggaaat
    23461 ctatattttt gatgacagct tttctgcatt agattatcaa acggatgcga agttacgtgc
    23521 tcgtctgaaa aaagaaacga cagaatctac tgtattgatc gtagcacaac gtgtgggaac
    23581 gatcatgcat gcagataaga tcatcgtatt aaatgaagga gaagtcgtcg gtatggggac
    23641 gcatcgggag ttgttggaaa aatgcccgat ttattatgat attgccgctt ctcaattatc
    23701 aaaggaggaa ttagcatgaa aaaaaccttt tcttccttaa aacgtttagc tcgatatatc
    23761 agaccgtatc gtgagacttt tcttttagtg atcctattta cagttctgac agtggctttc
    23821 aacgtggctt tgccatatgt tacaggactt cctactacag aaatcagccg taatattgcc
    23881 aatggcgaat caatcaattt ttcttatata ttcaaatgtc tcatttggat cacagttgtt
    23941 ggaatagggt attgtatttc gcaattactt tctggtgttt tgatgacaaa tgtcgttcaa
    24001 agtgccatgc atgatttgag aagagacata gaagaaaaaa tcaatcgtct tccggtttca
    24061 tatttcgata aaaaccagca aggaaatatt ttgtctcgtg tgacgaatga tgtagatgca
    24121 gtcagcggtg ctttacaaca agcttttatt ggtatcgtaa atgcgatatt gggaattacg
    24181 ttggctgcag caatgatgtt ttatatccag ccgatgatgg cgctgatctc tatgatcatg
    24241 attccaacat cgatctggat ctcaaaacga gtgatcaatg cttcgcagaa atattttcaa
    24301 agcatgcaga attctcttgg tgagctaaac ggctacgtcc aagaaaatat gacaggtttt
    24361 agtgtattga aagtatatgg acgcgaaaaa gaaacattgg aaggattcaa aaaagttaat
    24421 cacagcttga aatactttgg gtttcgtgca gcattcattt ctggcttgat gatgcctcta
    24481 gttcaattaa ctgcctatgc tacttatatt ggtatggctg ttctaggaag cttttatgtt
    24541 attactgggg cgatcgttgt cggtcaacta caagcattca tccaatatat ttggcaaatc
    24601 agtcagccaa tggggaacgt gacacaattg tcttcagttt tgcaaagtgc atcagcggca
    24661 acgaaacgtg tattcgagat tttagatgag ccagaagaaa aagaaaacaa agtagatgct
    24721 tcactgccag aaacgatttt aggagatgtg acattcgatc atgtcgattt tgcatatgat
    24781 ccgaagaaac cattaatcca agatttgaat tttgaagtga aagctggtca aaccgtagct
    24841 gtggtcggtc cgaccggtgc cggcaagacg acattgatca atctattgat gcgtttttat
    24901 gacgtagaca aaggagcaat aaggattgat ggaatcgaca ccaaatcaat gagtcgcagt
    24961 gatgtgcgtt cgctatttgg tatggtcttg caagatgcat ggctttatca aggaacgatt
    25021 gcagataata tccgcttcgg aaagcttgat gcgacagatt atgaagtagt tgatgctgcg
    25081 aaaacagcaa acgtagatca ttttatccga acgatgccag atggatatga tatggccatc
    25141 aattctgagg gagacaatgt gtctttagga caaaaacagt tgctgacgat tgcccgagca
    25201 gtggtctccg atcctaaaat cttgatttta gatgaagcaa caagttcagt agacacccgt
    25261 ttagaagcgt tgattcaaaa agcaatggat cgcgtgatgg agggacggac aagtttcgtc
    25321 atcgctcacc gtttatcgac aatccgtgat gcagatctga ttctagtgat ggatcaaggt
    25381 cagatcattg aaaaaggaac gcatgagagt ttattggcac aaggtggatt ttatgaaaaa
    25441 ctgtataaca gccaatttgc tgaggaagca gaataagtca tataagaata aaacagttta
    25501 aaacttattt tttgttctct attcttgata atggtaaagt aaagttatca agaaaagtga
    25561 ggacacggag atggaacagt ttttaaatga aaaaattact gaagccaaaa gagaagttga
    25621 tcgtttaacg cacgtctgtc agacgaagcc ttttgattca gctgattttt ttgaaaatga
    25681 gtttcaaatc gaacgcttgg cagcacaaat agaagtgtac gaattaattt taaaaaaagt
    25741 aatagaagaa aatatagatg tacaataaaa acaggtaaaa cgtcagttac cagatactgt
    25801 aaatagacat ctggcctgag caggttttac ctgttttttt tcttatgaaa taaatatatg
    25861 ctatgatacc tttattcaat aggattagtt tctacaaaaa atgaaaggag aaaaataaat
    25921 atggaacggt ttatagcatc aaatgccaca gtgattggtg atgtgacatt gtcagaagat
    25981 gtgacgatct ggtatcaagc tgttttacgc ggggacagta attggataaa aataggacaa
    26041 agaacgaata tccaagatgg tacaatcatc catgtcgatc atgatgcacc tgtagatatt
    26101 gcggagaatg tgacggtagg acatcagtgc atgctacatg gctgtacaat cgaaaaaggg
    26161 gcgctgatcg ggatggggac cacgatattg aatcatgcgg ttattggtga gaatagtttg
    26221 attggtgctg gatcattagt aacagaagga aaagttattc ctcctaatgt cttggctttt
    26281 ggtcgcccag ctaaagtgat ccgtcctttg acaaaagaag aaatacaaaa aaacaaagaa
    26341 aacatccagc attatgtcga gataggtcgg atgcatgcgc aaggaaaatt caaggagcaa
    26401 agataggcag tagcatccat aaaataaaaa aggatggtca gtttgagttg accatccttt
    26461 tttatttggt ttagataaga gagcttaaaa aagcttcctt tgaaacagat taatttaatg
    26521 aagaactgtt ttccatgact tcatcgatca atccatatgc ttttgcttgt tcagctgtca
    26581 tatagttgtc acgatctgta tctttttcaa tcacttcaag cggttgtcca gtgcgttcag
    26641 ctaaaatttt gtttaagcgt tcgcgtgttt gcaaaatatg gcgtgccgca atttcgattt
    26701 cagttgcttg cccttgagcg ccgccaagag gttgatggat catgatctca gcatttggta
    26761 aagcaaatcg tttacctttt gtaccagctg tcagcaagaa gcttcccatt gaagcagcca
    26821 tacccataac aattgtttgg acatctgctt tgacaaagtt cattgtgtcg taaatagcca
    26881 tacctgctgt aactgaacca ccaggagaat tgatataaag atagatatct ttttcagaat
    26941 cttgagcgtc taagaaaagc aattgggcga tgatcgaatt agcaagatca tctgttactt
    27001 ggccgcttaa catgatgata cggtctttca ataaacgtga gtagatatcg taagctcttt
    27061 cacctcgtga agattgttca atgactgtag gaattaaatt cataatagag ttcctccttg
    27121 atttcgttta gaaatagtgt accataattt agtttctaat acctaaaatg tagtatacat
    27181 ttttggtcaa aaaaggtcaa ataaaaaact taggcaaatt agtcgcataa acccgcttta
    27241 tggtatgata agcagagaaa caaaacaagg aggaacaaca gattgatagt tggtattact
    27301 ggccttatcg gagtgctgac aggtgctgta gttgtctata tcggcatgat actgcaaatg
    27361 cgtcacttgg aaaataaaga acagcgtaga cgtgaattgg aattgaaagt caaagaaatc
    27421 gagacgctga atcaattaaa taaaaagatc aacgagatct tgcaaaaacg gacaacgctg
    27481 atggaagaat atgtcagctt tgatgcattt gatgattgtt atatcacgat tgacgatttt
    27541 gcgtatctcc aatcattttc agcgcaaaat agtttttatc tgccaaatta tattttagac
    27601 gagctattta agaatatctc ccatcgaaaa gtgattttat ctccagatga aacaatgaag
    27661 attggtggat atgcttataa aggcggacgc gtgattttag agaattttac ggatagtctg
    27721 actgaaatga tcaatgaaaa aaaagctcag ttgaagacta tgacgcgcca gccgattggt
    27781 ttcttctcga aagatgatgt ttggagctga tattttgaag cattgccgtt gcacatgaga
    27841 gcgtggtaat gctttctttt tttcttaatg atacaataga actgaacgga gtgaagaaag
    27901 atgttacaaa tctatgccca tcgcggaagc agcggcaccc acccagaaaa tacgcttcct
    27961 gcatttgcag aagctgtacg agtaggtgca gatggtatcg aactagatgt ccatctaagc
    28021 aaagatggtt atttgatcgt tatgcacgac gaagaagtgg accggacgac taacggtaaa
    28081 gggctgattc gagaaaaaac attggaagaa ctcaaaaaat tgaatgcagg gggcaaattc
    28141 agcaaagaat ttccagcagc taaagttcct gaattgagag aagtgttagg actgctcctc
    28201 caaaaaaatt accgagggat gctaatgatt gaaattaaaa ctgatcagta tgaatatccc
    28261 ggtatcgaag aaaaattagc cgaaacatta aaaagtagag attggccttt tcaacatgca
    28321 tattgcagct ttcatttgga ttctttggaa aaaatcgcat tactggaacc ggagatacag
    28381 ctggacttat tgatgagtac ttctgataaa aagatccaac tagcagcaga aaccccttat
    28441 atagaaggag tacatccaaa aaatacttgg ttgttcgaac atccagtcca ggcagctgat
    28501 tttccaaaag caattcgtgc atggacgatt aacgatgaag aagaaatggc caaatgtcaa
    28561 gaactcaaaa tagatggaat aataactgat tttccggaga aagctcttcg gtggaaacaa
    28621 tcaacgaaaa gtaggtaaaa tatggaaaaa gtattagtga tcgtcggtcc gacagcagtc
    28681 ggtaaaacag cgctaagtgt ggaactcgca caactatttg gaggagagat catcagtggt
    28741 gattcattgc aaatctataa aaatctggat atcggtacag caaaaatcaa agaagaagag
    28801 atgaataatg ttccgcatca tttgattgat gtgatcgaac ctactcaacg ttactcagcc
    28861 gctgattttc agcattcagg tcgacaattg attaccgaga ttgcgaaccg agggcaccta
    28921 cctatcatag ctggtggtac gggtctctat atccaatccc ttctatatga ttatcagtta
    28981 ggagcgacag aagaagcgaa tcctgagatt agaaaaaagt atgaaacgtt agctgaaaca
    29041 attggttccc aagcattatg gaatcagttg aaagaaaaag acccggcagc tgctgagaaa
    29101 atccactgga acaatcaacg caaagtgata agagctctgg aagttttaga gacgacagga
    29161 catagtatca cggcacctaa agaagagcca aagcaattgt atgattacct catgattgga
    29221 ttagatacga agcgtagtat tctttatgaa cgaatcaatc aaagagtcga tttgatgcta
    29281 gcagaaggtt tagtagcaga agcgcgtaag gtgtatgagc ttggagaagt ccaggccagt
    29341 caaggtattg gatataaaga atttttccct tattttgaag ggaaagaaac attggaagaa
    29401 gcaacagaac aagtcaaact acattcgaga agatacgcga aacgtcagtt gacgtggttt
    29461 cgtaaccgtt tggatgcaca gtggtttgat cttataagtg agccaaatca aaaaagtcag
    29521 attgagcaaa caatcaaaaa atggctggag gcggaataaa atggaagaaa aagtgatcat
    29581 cgtaggggta gaaaccgaag caaaccagcg ttacttttca gagtcaatgg aagagctagt
    29641 tcagctgacg aataccgcat caggagaagt cgtattcaca attacacaaa agagaccaca
    29701 agtggatcgg caaacgatta tcggtaaagg gaaattacaa gaattagttc aacaagcgga
    29761 tgcgcatgaa gcggatttga tcatctttaa tcatgagcta actccgagac agagccaact
    29821 gattaccgat gctgttggtc ttccggtaat tgatcgcgtg cagcttatct tagatatttt
    29881 tgcgatgcgt gctcgttcga aagaagggaa gctgcaggtt gaacttgctc agttagaata
    29941 cctgctgcct cgtttagtag ggcaagggaa aacattatct cgtcttggcg gtgggatcgg
    30001 aacaagaggg ccaggtgaaa caaagttaga aacagaccgc cgacatatac ggaataaaat
    30061 ttttgctgtt aagaaagaat tgaaagaagt agaagctcat cgagagcgca atcgccaaaa
    30121 aagaaaaaat agcgagattt ttcagattgg acttattggc tacacgaatg ccgggaagtc
    30181 aactatcttg aatctattga cacaagcgga tacttattcg aaagatcaat tgtttgcaac
    30241 gttagatcca ttgactaaga gatggcgttt tgctgaagga tttgagatta ctgtaacgga
    30301 taccgtcggg ttcatccaag acctgcctac gcaactgatc gatgctttcc attctacatt
    30361 agaagaaagt caaaatatgg atcttttgct acatgtagtc gatgctagtt ctccagatcg
    30421 tattttacag gagcagactg tcttaaaatt gatggatgaa ctgaatatga aagaaatgcc
    30481 gatactgact gtttacaata aggcagacca gatcgaccca gcgatgttca cgcctacgct
    30541 attcccaaat gtattgattt ctactcagac gaaagaaggt aagatggcgt tgatcgaagc
    30601 aatcaaacgt cagctgatgg aactaatgac cccttataca ctttctgtgc caagcaacga
    30661 aggacagaaa ttaagcgagt tgagaagaca aacaatggtt ttggacgaag cgtacatgga
    30721 agaaacaaac gaatatgaag ttaaagggtt tgcaaaaacc aattcaaaat ggttaagaaa
    30781 aaaccaataa aatt
//
LOCUS       DACCVH010000028        29100 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.028, whole genome shotgun sequence.
ACCESSION   DACCVH010000028 DACCVH010000000
VERSION     DACCVH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.028"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1031)
                     /locus_tag="IVV98_001291"
     CDS             complement(<1..1031)
                     /locus_tag="IVV98_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7806960.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="IVV98_001292"
     CDS             complement(1113..1802)
                     /locus_tag="IVV98_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7806961.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IVV98_001293"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IVV98_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP7806962.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="IVV98_001294"
     CDS             complement(2329..2832)
                     /locus_tag="IVV98_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP7806963.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IVV98_001295"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IVV98_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP7806964.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IVV98_001296"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IVV98_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP7806965.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="IVV98_001297"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="IVV98_001297"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP7806966.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="IVV98_001298"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="IVV98_001298"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP7806967.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="IVV98_001299"
     CDS             complement(6444..7463)
                     /locus_tag="IVV98_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP7806968.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8523)
                     /locus_tag="IVV98_001300"
     CDS             complement(7636..8523)
                     /locus_tag="IVV98_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7806969.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IVV98_001301"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IVV98_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP7806970.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IVV98_001302"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IVV98_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP7806971.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IVV98_001303"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IVV98_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7806972.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="IVV98_001304"
     CDS             9754..10398
                     /locus_tag="IVV98_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7806973.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="IVV98_001305"
     CDS             complement(10454..10957)
                     /locus_tag="IVV98_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP7806974.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="IVV98_001306"
     CDS             11554..12519
                     /locus_tag="IVV98_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP7806975.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="IVV98_001307"
     CDS             complement(12618..13790)
                     /locus_tag="IVV98_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806976.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="IVV98_001308"
     CDS             complement(13777..14922)
                     /locus_tag="IVV98_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806977.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="IVV98_001309"
     CDS             complement(14936..15868)
                     /locus_tag="IVV98_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806978.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="IVV98_001310"
     CDS             15985..17064
                     /locus_tag="IVV98_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7806979.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="IVV98_001311"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="IVV98_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="IVV98_001312"
     CDS             complement(17789..18016)
                     /locus_tag="IVV98_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7806980.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="IVV98_001313"
     CDS             complement(18119..20707)
                     /locus_tag="IVV98_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP7806981.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="IVV98_001314"
     CDS             complement(20727..21386)
                     /locus_tag="IVV98_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7806982.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="IVV98_001315"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="IVV98_001315"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP7806983.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="IVV98_001316"
     CDS             complement(22159..23025)
                     /locus_tag="IVV98_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7806984.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="IVV98_001317"
     CDS             23134..23775
                     /locus_tag="IVV98_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP7806985.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="IVV98_001318"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="IVV98_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP7806986.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="IVV98_001319"
     CDS             complement(25216..26115)
                     /locus_tag="IVV98_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7806987.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="IVV98_001320"
     CDS             complement(26117..26914)
                     /locus_tag="IVV98_001320"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP7806988.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="IVV98_001321"
     CDS             complement(26892..27596)
                     /locus_tag="IVV98_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP7806989.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="IVV98_001322"
     CDS             27727..28302
                     /locus_tag="IVV98_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP7806990.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="IVV98_001323"
     CDS             28420..29097
                     /locus_tag="IVV98_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP7806991.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6167 c         5232 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa
//
LOCUS       DACCVH010000029        26558 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.029, whole genome shotgun sequence.
ACCESSION   DACCVH010000029 DACCVH010000000
VERSION     DACCVH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.029"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            147..1016
                     /locus_tag="IVV98_001324"
     CDS             147..1016
                     /locus_tag="IVV98_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP7806992.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="IVV98_001325"
     CDS             1225..2250
                     /locus_tag="IVV98_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP7806993.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="IVV98_001326"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="IVV98_001326"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP7806994.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="IVV98_001327"
     CDS             3333..5036
                     /locus_tag="IVV98_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7806995.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="IVV98_001328"
     CDS             5038..7071
                     /locus_tag="IVV98_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7806996.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="IVV98_001329"
     CDS             7082..7522
                     /locus_tag="IVV98_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7806997.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="IVV98_001330"
     CDS             complement(7722..8849)
                     /locus_tag="IVV98_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7806998.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="IVV98_001331"
     CDS             complement(8852..9529)
                     /locus_tag="IVV98_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7806999.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="IVV98_001332"
     CDS             9793..11559
                     /locus_tag="IVV98_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP7807000.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="IVV98_001333"
     CDS             11574..12011
                     /locus_tag="IVV98_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7807001.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="IVV98_001334"
     CDS             12024..13175
                     /locus_tag="IVV98_001334"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP7807002.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="IVV98_001335"
     CDS             complement(13237..13935)
                     /locus_tag="IVV98_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP7807003.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="IVV98_001336"
     CDS             complement(13928..15280)
                     /locus_tag="IVV98_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP7807004.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="IVV98_001337"
     CDS             complement(15503..16903)
                     /locus_tag="IVV98_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP7807005.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="IVV98_001338"
     CDS             17064..17801
                     /locus_tag="IVV98_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP7807006.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="IVV98_001339"
     CDS             17926..18405
                     /locus_tag="IVV98_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP7807007.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="IVV98_001340"
     CDS             18402..19169
                     /locus_tag="IVV98_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807008.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="IVV98_001341"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="IVV98_001341"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7807009.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="IVV98_001342"
     CDS             complement(20072..20674)
                     /locus_tag="IVV98_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7807010.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="IVV98_001343"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="IVV98_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="IVV98_001344"
     CDS             21355..21939
                     /locus_tag="IVV98_001344"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP7807011.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="IVV98_001345"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="IVV98_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP7807012.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="IVV98_001346"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="IVV98_001346"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP7807013.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="IVV98_001347"
     CDS             23840..24019
                     /locus_tag="IVV98_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807014.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="IVV98_001348"
     CDS             24041..25066
                     /locus_tag="IVV98_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP7807015.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25257..26501
                     /locus_tag="IVV98_001349"
     CDS             25257..26501
                     /locus_tag="IVV98_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP7807016.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
BASE COUNT         9063 a         4691 c         5420 g         7384 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatcca gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaattgt aggaaaataa aaaggagctg ttgtttgtgg
    25261 tagattacaa aacgtttgac cctgatcttt gggctgcgat cgccaaagaa gaagaaagac
    25321 aagaacataa tttggagctg attgcctctg aaaactttgt ctccgaagca gtgatggctg
    25381 cacaaggaag tatcttgaca aataaatacg cagaaggtta tccagggcat cgctattatg
    25441 gtgggtgtga atttgtcgat atcgttgaaa atttagcgat tgaccgtgca aaagaattat
    25501 tcggagcgaa atttgcgaac gtccagcctc actccggctc tcaagccaac acggctgctt
    25561 atctcgcttt ggtagaacca ggggacacga tcttaggaat ggatctttcc gcaggcggac
    25621 atctaacaca tggatcacca gtcaacttca gtggcaaaac ctatcacttt gttgcttacg
    25681 gtgttgatcc gacaacagaa gttattgatt ataatgtggt acgtatttta gctagaaaac
    25741 atcaaccaaa attgatcgta gcaggtgcca gtgcttacgg acgaacgatc gactttgcga
    25801 aattcagaga aatcgcagat gaagtaggcg caaaactgat ggtagatatg gcacatatcg
    25861 caggattagt agcagcagga cttcatccta atccagttcc ttatgcagat atcacaacga
    25921 ctaccactca taaaacattg cgtggccctc gaggcggcat gattttgaca aacgatgaag
    25981 cattagcaaa aaaaataaat agtgcggtat ttcctggtat tcaaggcggc cctctagagc
    26041 atgtgattgc gggtaaagca gtagcattca aagaagcatt agatcctgca tttaaagaat
    26101 atagtgaaca aatcatcgcc aatgcaaaag caatggtcaa agttttcaat caagcaattg
    26161 gaaccagagt catttcaggg gcgacagata atcatctgat gttgatcgat gttcgcgagt
    26221 taggtataaa tggaaaagaa gcagagagca ttttggacag tgtgaatatc actgtaaata
    26281 aaaactcgat tccttttgaa acactaagtc cattcaaaac aagcggtatt cgaatcggca
    26341 cgccagcaat cactactcgc gggttcaaag aagaagatgc tgtaaaagtg gctgaactag
    26401 ttgtcaaagc attacaagca aaagatgata acgctcaact agacgaagtc aaaacaggtg
    26461 tacgcgaatt aactgaaaaa tttccgttgc ataaaaaata aaaatttaaa ttccattagt
    26521 aaacagaaaa gttcaatgtt gggcttttct gtttattt
//
LOCUS       DACCVH010000030        26130 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.030, whole genome shotgun sequence.
ACCESSION   DACCVH010000030 DACCVH010000000
VERSION     DACCVH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.030"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..205)
                     /locus_tag="IVV98_001350"
     CDS             complement(<1..205)
                     /locus_tag="IVV98_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807017.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKND"
     gene            complement(296..748)
                     /locus_tag="IVV98_001351"
     CDS             complement(296..748)
                     /locus_tag="IVV98_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7807018.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(761..1171)
                     /locus_tag="IVV98_001352"
     CDS             complement(761..1171)
                     /locus_tag="IVV98_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807019.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1446..1658
                     /locus_tag="IVV98_001353"
     CDS             1446..1658
                     /locus_tag="IVV98_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807020.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1661..1873
                     /locus_tag="IVV98_001354"
     CDS             1661..1873
                     /locus_tag="IVV98_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807021.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(2165..2389)
                     /locus_tag="IVV98_001355"
     CDS             complement(2165..2389)
                     /locus_tag="IVV98_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP7807022.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2467..2655
                     /locus_tag="IVV98_001356"
     CDS             2467..2655
                     /locus_tag="IVV98_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807023.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2981..3316
                     /locus_tag="IVV98_001357"
     CDS             2981..3316
                     /locus_tag="IVV98_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807024.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3549..4490
                     /locus_tag="IVV98_001358"
     CDS             3549..4490
                     /locus_tag="IVV98_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP7807025.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4492..5382
                     /locus_tag="IVV98_001359"
     CDS             4492..5382
                     /locus_tag="IVV98_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAP7807026.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5425..6225
                     /locus_tag="IVV98_001360"
     CDS             5425..6225
                     /locus_tag="IVV98_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP7807027.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6240..7091
                     /locus_tag="IVV98_001361"
     CDS             6240..7091
                     /locus_tag="IVV98_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7807028.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7292..7753
                     /locus_tag="IVV98_001362"
     CDS             7292..7753
                     /locus_tag="IVV98_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7807029.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7779..8231
                     /locus_tag="IVV98_001363"
     CDS             7779..8231
                     /locus_tag="IVV98_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807030.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8337..8531
                     /locus_tag="IVV98_001364"
     CDS             8337..8531
                     /locus_tag="IVV98_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807031.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8562..8948
                     /locus_tag="IVV98_001365"
     CDS             8562..8948
                     /locus_tag="IVV98_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807032.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8945..9148
                     /locus_tag="IVV98_001366"
     CDS             8945..9148
                     /locus_tag="IVV98_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAP7807033.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            9145..9441
                     /locus_tag="IVV98_001367"
     CDS             9145..9441
                     /locus_tag="IVV98_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807034.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9517..9933
                     /locus_tag="IVV98_001368"
     CDS             9517..9933
                     /locus_tag="IVV98_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAP7807035.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            10741..10971
                     /locus_tag="IVV98_001369"
     CDS             10741..10971
                     /locus_tag="IVV98_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807036.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            11130..11963
                     /locus_tag="IVV98_001370"
     CDS             11130..11963
                     /locus_tag="IVV98_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAP7807037.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11956..13371
                     /locus_tag="IVV98_001371"
     CDS             11956..13371
                     /locus_tag="IVV98_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HAP7807038.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13383..14912
                     /locus_tag="IVV98_001372"
     CDS             13383..14912
                     /locus_tag="IVV98_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7807039.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            15004..15882
                     /locus_tag="IVV98_001373"
     CDS             15004..15882
                     /locus_tag="IVV98_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP7807040.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15884..16201
                     /locus_tag="IVV98_001374"
     CDS             15884..16201
                     /locus_tag="IVV98_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807041.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16250..16951
                     /locus_tag="IVV98_001375"
     CDS             16250..16951
                     /locus_tag="IVV98_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP7807042.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            16966..17856
                     /locus_tag="IVV98_001376"
     CDS             16966..17856
                     /locus_tag="IVV98_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAP7807043.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17879..18094
                     /locus_tag="IVV98_001377"
     CDS             17879..18094
                     /locus_tag="IVV98_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807044.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18106..18447
                     /locus_tag="IVV98_001378"
     CDS             18106..18447
                     /locus_tag="IVV98_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807045.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18447..18818
                     /locus_tag="IVV98_001379"
     CDS             18447..18818
                     /locus_tag="IVV98_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807046.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18811..19206
                     /locus_tag="IVV98_001380"
     CDS             18811..19206
                     /locus_tag="IVV98_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP7807047.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19208..19585
                     /locus_tag="IVV98_001381"
     CDS             19208..19585
                     /locus_tag="IVV98_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807048.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19586..20194
                     /locus_tag="IVV98_001382"
     CDS             19586..20194
                     /locus_tag="IVV98_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7807049.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20194..20535
                     /locus_tag="IVV98_001383"
     CDS             20194..20535
                     /locus_tag="IVV98_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807050.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20777..23566
                     /locus_tag="IVV98_001384"
     CDS             20777..23566
                     /locus_tag="IVV98_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAP7807051.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23556..24296
                     /locus_tag="IVV98_001385"
     CDS             23556..24296
                     /locus_tag="IVV98_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7807052.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24293..>26130
                     /locus_tag="IVV98_001386"
     CDS             24293..>26130
                     /locus_tag="IVV98_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807053.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         9489 a         3716 c         5324 g         7601 t
ORIGIN      
        1 tatcattttt taacatagta atttgtttat ttaaatctga tagtgtttct tccttactta
       61 atataaatct ttctctatca tgtaatttat ttagtttttc atcatttttt tgttctaatt
      121 cataagcttc tttttttatt gtgttagctt tcgacagttt agtgattcct ataattaata
      181 aaataagtcc aatcaataat aacattcaaa actcctcatt tctttgatat aattattgta
      241 gagtttactc agaaatgagg aaagagtcca tgtgaaagca tgggcttttt tatttttaat
      301 gttgtaatac taaatgttca agattatgag gaagccctaa atattcaata atttggaact
      361 gactcatatc agataaatct tgttcatcta ttgttctagt taacatttca attgcaaaca
      421 tattagcttc agcttctata ccataaatca tacaactaag gttgtttgct ctaaaagctg
      481 ctgtgcaaat acctttatgg agtctaacgt gggctatttc atgccataat acaaatcttt
      541 tcatagaagg tgataggttt tgattaatta atatcacata acatctttta ttgtgtatcg
      601 tttgtcctaa tgttttattc cctaaatcag tttcaattaa atctatatca gaatatttga
      661 ttattttata tggattaatc gcatcagatc caaactctac aaataatttt tctatttctt
      721 ctaatatcca gtatttgttt aaatgcatac caaagcccac ctattgacga tattttttag
      781 gagtgaattt tttctttgct ttaactttgg ttaaggcaag tgcaagttga atggcatcgt
      841 ataatttttc cttatcttca tcgtctaaag gttcaccata ataatttgtt tcagcatctg
      901 aattcaagcc ttcaagtaat ttttcagctt gtaaagcaat atcttgttta tctttttctg
      961 ttaaatcata ataatggcgt ttatcagtac gtcctaaaag ataatcagtt gatacattaa
     1021 agtaatctgc aactttttgt attttatctc cagatggagt acttttattc catctagaca
     1081 tgcttccatt tccgaaattt aactttcttt caagttctgc caacgtcatt gaacgttctt
     1141 ttaataagat ttttatacgg tctaatagca taggatatgc attcctttca aaataccgac
     1201 aaaaaaagta tttttctgca aattatctat ttacaaatag agaatttgca gttatactag
     1261 ttttgtaagc aagatattta cggcatacaa agactaaaag caataaacta atagtctccc
     1321 cagacatcag taagctcgct ttttgtgcgc tgtattttgt atgcttacat aatagcatat
     1381 ttgcagtttt tgtcaaactt attagacaaa aatattagaa aatattcgat aagggggtat
     1441 gaagcatgac tttaaaacag caagtattaa ttgctttagt aaagaaaggt tggagtcaaa
     1501 gagagttagc tcgacgaatg ggtatatcaa ttacttattt acgagatatc ttcatcgaaa
     1561 aaagaaaacc taaggaacgt ttaaaacaaa tcgaagaact tttggatatc aagttagaag
     1621 tagattctaa tgatcagcca tcagaacagg aggcgtaaaa atggtacaac gtttgagcaa
     1681 agcggagttt aaagagaaat ataagtattc tgaaagtact tatcaaagaa gaatgaagga
     1741 atttaaaaaa tcacgtttta gtgaggggta taacgcagtt acttccaaag aaataacaat
     1801 tgatgtcgat ttatatgaac agtttagaac atggcgttct aaaaatcgat ttagagttag
     1861 agctgtttgt taatagctaa aaaatctaaa ttcaccactt ctgaaaagag gagttgctgc
     1921 tctcctttca agtttgccaa agtccacgtt ttttcatttt ggcaactcct cttcttggag
     1981 gtggtgacgg cgagagacga aggagggatg acatgaagga agaatcaaaa atagggattt
     2041 tgaatgagaa caattacaca agattaatta ttgaaacaga agaagggaaa aaagtagcag
     2101 aagttacatt gaccgatgca actcctgctg acggttatcg tattcgatta actcctaaat
     2161 atgattaacc ttttggtggg tgtggatcgt ttccgtgact atcacggctt tgaatttttc
     2221 catctctgcc atgaataaat agctcagatc cttgattttt agaaatctct ctagcgattt
     2281 ttactgcttc tgattttgta ttagtatgtg cagtcgcttt agaatttcca gcacctttga
     2341 cattccaacc accattggaa ttaggtacaa catgttgatt ttttcccata gttttcacct
     2401 ccatttctat agaaatattt tatcaaatag aaatggagaa attcaataaa cgaaaggaga
     2461 agtgatatgg catatacctt gcaacaagaa catcaaattc tcggtttgat taaacaacgc
     2521 aggaaacaat tacaagatga ccgtgcagcg cttagaaaag ccgatgagct atcagatagg
     2581 caagctgaac taattgcttc tgaacttgag gatttgagaa tgctagaaat aaaaaatagg
     2641 gagattagat tatgaagaag acagacacac tttttatagg attcattttg gggttattag
     2701 tgattgtagc gcaccaaagt attatcgggg gaagcttgtt cgcagcattg atggttttaa
     2761 tcaatctgct tgattcaaaa gaaaggagca actatggcac gagaagaagc gctaaaaatc
     2821 ggtaaagtga ttgctgataa tcggtgggga aatagccgcc ctattatttt aagcaagcaa
     2881 catatcgaaa agcaaaaagc atggcaacaa ataaaaaagt gactctgcca gccagcaaag
     2941 agtcacatac aaatttataa aactaggaga attatatcac atgaataaga aaattgaaaa
     3001 tcttatcgaa gaattgaaac gtgaatgcca aaagcaaggt gtttctatta tttgtacagc
     3061 ccaaaaagaa ggggaactta aaagtctcgt ttatggtgag acaacagaaa ttttactttg
     3121 tcttgctatg caagaagaac atttagatga aaatctccca ttgtcagcac atattatgcg
     3181 tagaattgct gtggatgctt acgaacaagc gaaaaatgaa gaagaaaatc aaccttcaaa
     3241 tcatactttt gttattaata acaaggaaga tttagctgat gtgatgactc gtattctcaa
     3301 gggggaattt caatgatgaa tgaaaaaaca attgatctac tcattatttt atttttcacg
     3361 ttagtgattg tagcgaaaag ttatgtaatc tttggcttgt tattcgcaat taccatgctt
     3421 gtgctttgcg tgttagcaag cagaaaagag gttaaacatg aacgagttag caaatcttga
     3481 caactattta actgatcctg attatgctaa accaccatat gaagcaccaa ttgatgagga
     3541 ggatgaagat gagtaaatct accttagaaa tgagccatca agaatggctt gaagaccgta
     3601 agaaaggcat cggaggttcg gatgttggaa caattttagg attgaataaa tggaaatctc
     3661 cttatcaact atggctagaa aaaacaggac aagtagtact tgaagaatca ggaagtgagc
     3721 ccgcttattg gggtaatgtt ttagaagaag tggttgctaa agagtttcag gaacgtacag
     3781 gcaaaaaagt acgcagaaga aaccaagtat ttgaacatcc attacatcca tttttaagag
     3841 caaatattga tcgggaagta gtgggagaaa atgccattct ggaatgcaaa acagctaatc
     3901 aatttctcgg taaagaatgg gaaggcgaag aggtaccgct tagctatctc tgtcaagttc
     3961 aacattacat gaacgttcta aacaaagact attgttacat cgctgtctta atcggtggtc
     4021 aaaaatttat ctggaagcgg attgaacgag atcaagagct gatcgataca atcactgaac
     4081 aattagtaga gttttgggaa acaaacgttc ttggaggtat cgagccaatt attgatggta
     4141 gtcaagcgac agctgatttc ttgaaagaga agtatgcaga tgttgaagac gttcaaacga
     4201 cgttaccaat tcatttcgat gaactagttg aacagaaaaa cgaactcaaa cggactaaga
     4261 aagaaattga atcagctatc cgtcaagtag acaacgagat tatcagcgag ctaggtaaac
     4321 gtgaagccag tatcggtatc actcaaaaaa acatcatcag ttggaaattt gtccgtacga
     4381 gacgtatgaa ctcgaagaaa ctagcagaga aatatccaga tgtcgcaaat gatgaagaga
     4441 tttataacgt tactgaatca agaaggctaa ccgaaaggga gatcaaataa tatggcaaca
     4501 aatgaatcgt taaaaaatca attggcagca aagccacaga aacaagttgc accaggtcaa
     4561 ttaggactta aagctttgat gaatacacca acaatgagaa agaagttcga agaggtgctt
     4621 catgacaatg ctaatgcttt tatgtcgaat gttatgactc ttgtatctaa tgacagttat
     4681 cttgcagata gtgaaccgat gtctatcatg agtggtgcgt taactgctgc aacattaaat
     4741 cttgggctag ataagaattt aggttatgca tatttagttc cattcaatag taaaaacaag
     4801 caaacaggaa aatgggaaaa gaaagctcaa ttcatgcttg gctataaagg atatatccaa
     4861 ttagcccaac gatcaggtaa atacaaagca ttaaatgtga tcgaagttta cgaaggagaa
     4921 ctaaaaagct ggaaccgact gacagaagag tttgagtttg atccaaatgg tagaacgtct
     4981 gatgaagtca ttggatatgt tggctatttc gagttactga atggattcaa aaaaactgtc
     5041 tattggacca aacaagaaat cgaagctcat cggattgcta acaataaaga tcgcgataag
     5101 acaaagttaa gtggtgtgtg ggcatctgat tacaatgcaa tggcacgaaa aactgttttg
     5161 agaaatcttc tttctaaatg gggaatcttg tccatcgaaa tgcaagaagc caccacatcg
     5221 gatgagagag tccaaagggt tcaagaagac ggcagcatta ttgctgaaac agaagttgaa
     5281 gaagatattc ctgaaagaaa agaagcagag gttatatctg aagaaaatga agatgtacaa
     5341 actggattat ttgatgcatc taatccgccg ttaaacaaat aatgagggag ctttctccct
     5401 tgcttttcta gaggagaaat acgaatgaac acaggatatg tcaaattaca tcgaaaagtg
     5461 atgaattcat tcgtttggac caatccttat atgtataaat tatggaactt gtgtttgatg
     5521 aaagcgagtc atgagaatcg caagatactt tttaatggaa aagagataca agtgaacagc
     5581 ggagaattcg tcacagggcg cgatgctatc acatctgaga tgaacgaagg cgtgaaacgt
     5641 gaacatcaag tgaacagcgg ttctgtatgg agatggctaa aacaatttga aaaaaacgga
     5701 atgttgaaca tcaaatcaac tacgaaatac agcgttatat caataaaaaa ctggtctttg
     5761 taccaaagca gtgaacaaca aatgaacatc aaacgcacaa caagtgaaca acaagtgcac
     5821 acaaacaaga atgaaaagaa ttataagaat gaaaagaata ataaaacatc atcgtcgcaa
     5881 ccacgcaaaa agcgtgttta cgacaccgac tcagtttact acattctcgc ggaggagtta
     5941 ttcaaacaga tttgtcagaa tcaggaaatc aaaaagccga atctgcaaag ttgggcagat
     6001 aacattcgga aaatgatcga gatcgacaag cggaccgaaa accaggtacg gggaatgatt
     6061 gaatggagtc agcacaatgt gttttgggca tcgaatattt tatctgctaa aaaattgcga
     6121 gaaaaatacg acacaatggc agcgcaagcc aatcgtgatt ataaaacaaa acaaactaaa
     6181 acgcttgaat acgagaaatt tagcacagat gagttgccta tttgagagga ggcgtaggca
     6241 tggaaactgt tggggaaatc atggaaaagc tgatacagaa agtgcttgtc caacgtggcg
     6301 aatgtcctga atgcggacag cctttgtatg gatggcgtac gaagaaccct gatggctcag
     6361 aacgttgtaa gccaacctgt atgcaatgtg ggtataaagc attgcgagtt caggaagact
     6421 tacaaacaga acgaatttac aacgagagcc tgaaagcaag agcaatcaat tttttcaaag
     6481 gtggttctgt tgtgcctaat caagcgttgt ttgattgcac attgcagaat tatcaaattg
     6541 tcgatcaaga aacaagacaa gcggttgaag taaccaaacg ctttgttaat tcagtcttgt
     6601 taggaaatcc aagtcacctt gttttaactg gaaaacaagg aacaggtaaa agtcacctag
     6661 cgatggcagc ggcttgggaa gtcttgaagc gatcaaacta cgataaaaaa atcttattta
     6721 tcgggttaca ggaaatgctg gatcaaatca aattttcgta caacaatcct gaactcagaa
     6781 aaacgattga gggatcgttg attgcagata tcaaaacagc ggatttagtc atcattgatg
     6841 atatcggttc agaactagga aaagatgcat cagatagtcg agcgtttggc ataaacacgc
     6901 taaattcgtt cttggatgca cgacagaacc tagcaacgat tatcacaacg aacttgcttg
     6961 gtgaagaact gaaaaaagct tacggtacga gaacaatatc aagaatgttt gtcaactctg
     7021 atggatttac gatggtattt tctcaaacag cagacaagcg cataaaacca gtcaaaggag
     7081 cgatcgcatg aatttgacta aacaagaaaa aagaatctgt cgtcagataa tgttgcaaat
     7141 tataggtgat cgtgacatgg acgaattatc tcaacaagag agtcgaatgg ttcggaagat
     7201 aagtaagcta attatttatc gggatacaga aagatttctc actgttttag gtaacgtcta
     7261 cgagaatcca gagttattgg aggtagagta attgccaaaa atattagatg catgttgcgg
     7321 tagtagattg ttctggtttg ataagaacaa ttctgacgta acatttatgg attgtcgtca
     7381 gcagtatgaa gaattatcaa caggtcatgt gatcaatgtt gatccagatg tggtcgcaga
     7441 ctttcgcgat atgccttttg aagatgatgt gttcgatatg gttgtatttg acccgccaca
     7501 cttaagacat gtcggcgaaa actcatggct tgccaaaaaa tatggaaaat tagacgaact
     7561 ttggccagaa gacatcaggc aaggttttgc agagtgtatg cgagttttac gaccttcagg
     7621 aacattaatt tttaagtgga acgaggaaca gataccactt tctgatgtgt tagaggctat
     7681 tggagaacag ccattgtttg gtaataaacg aagcaaaaca cattggcttg tgtttatgaa
     7741 aaaattcagc taacggagga aacaaaggag gaaaagtaat gaagattgta ttaaataaat
     7801 gttttggtgg ctttgggttg agccatgaag caaaaatgga aatttttaaa agaaaaaata
     7861 ttgaagtatt cccatacatc aataacttta gctatgactc agatgatgaa tacacgagat
     7921 acacaggcca aaagctaggt tcgatggatt ttatctacta tttcaaaaaa gacccgaaaa
     7981 tcgacaaagt tacaggaatt tatagcgaaa ttgaccgact gtacggaatt gctgatgatt
     8041 ccagtttttc aagtgattca aacagaggtg ataaggacct cgttgctgtt gtcgaaaaac
     8101 taggaagtga ggccagtgga ccatatgcaa gtcttaaagt cgttgatata cccgatgggg
     8161 ctgagtggga aataagtgat tatgacggcg ttgaaactgc acattatggt tttcaaacag
     8221 gtagtattta gtccactaat gacaactaaa gaggaggcag aaggatgagt gaagatgaat
     8281 actttgaaca gtagtctatt aacgacagag atttttaact ggaaaggggt gtagtcatgg
     8341 acgcatcgga agtagtaaat aaaattaata gtctcaaaga ggttttcgga gacgtcgaag
     8401 tagtgataaa cgcacaaggc tatgacaacg gattttttaa gcagattacc gacattagca
     8461 ttcagcaagg aatggaagac gaagatggaa actttatcga tgaagtagcc attttagtga
     8521 cttgcgagta agtaattgac agctaaagag gaggcagaag gatgaaaaaa ttgcaccaac
     8581 tcatatctga gaaagaaagc gaactccaaa atttagaaga tagtttggga ttggggtttc
     8641 caattgttga gcaagctaaa atgactcaaa tcagtcatct acgacttgaa ttggaagatt
     8701 taagacaaat agaaaaatca attcaactca acgacaacca gaaaatcgtg ttggagtggt
     8761 tgaaaagcga gacaatttta actagagaag caccaatatt atctgttaat gctttttctg
     8821 ataaaaattt actaggaaaa ttacctgata aagtacgcaa agcttataaa ctattggctt
     8881 gtaaacaaga atatgaagtc ctatcagcat tcgctcaatg gggattagaa caggaggaag
     8941 cggaatgaac aacagacatc gcagaataac aaaactaaga aaacaggaac tgaatgtact
     9001 aaagacaaag tttgaaaaag aatatggaat ttcagcagaa gaaacatata aagtggcaag
     9061 tcagtttgtt gctgatgcga gtaatgctat tcgtaagttt gggatttcga tattaaatga
     9121 tgatcgtaaa tgggaggaaa tgagatgaaa ataaaagacg gattttacgc tagtagtcat
     9181 ggtatcggcg gtttaatgct agacatgccg ataaagaacc ctaaaacacg tcagaaatca
     9241 aaattcaaaa tcggtgacat ggtccgatgt aaagcagaag agttcatcta tccgtttcgt
     9301 ggatatgtag agcatgtcta taatcattca gcaatcattc acattgaaaa cacgatggaa
     9361 tgcgataagt ggttagcgaa aagcaaagat aatttagcag tggctcgttt ggtggatatg
     9421 gaactaatca atgacaaata aaaaagccgg atcgctccga ctgattcaat aaatccaaca
     9481 catttattat atcacataaa ggagcggttt gacttgatgc aattgttacg agaggtagat
     9541 ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga actttcggcg tttggagcgg
     9601 atggcaggtc gctctttgat agatattaag tcgccgatta ttacggatat gccgaaggca
     9661 ccgaagcacg gcaataaggc agaagacgcg atcattcaga tgatggatat agaagcggag
     9721 agagacgcaa tactagcggc tttgatggct cttagtctga ttagccgtca gatactctac
     9781 tacagcttct gtgacgtaaa caagcactct aattatgaaa tagggcaatt gatacgagga
     9841 tacggagaga agaatgtaga gaagttgaaa tccatcgcat taatcgaatt tgcagaagca
     9901 tacaaaaaag gcgtgttagt tcagtatcgt tgattttgta gggtttttgt agggatagtg
     9961 tagggttttt gagcggttta acgtgatatt atggtagtgt cgaaagatta gtgataggtc
    10021 tgagacaaaa taaaatgtaa gggaggaaat ctccctcatc gttttaactt aagcttcgat
    10081 agacagcaac ggaaatatta agaataagga tgtgaatttc aactccttct aaattgttct
    10141 tattatctat catccgttgt tgtctattaa tttatgcatc ggaggaaaaa cgaatggata
    10201 aagaaatcaa agtaactgtc aaattagatt tgactgaact aaaagaactg ctcaacaagg
    10261 ctagtgacca agtcgaacag ttacaagaaa ctttagatga aattgctaat tttaaaatcc
    10321 aagtttctta gcagtatatt ttttagcagc tgcactcata aaatcatacc aagtatcaga
    10381 aaaatataac ttaactaaat aattaaaaaa ggtgggtaaa tagaaatgac ggcgttaata
    10441 atttcaattt ttgcgctctg tcttaatgtc tatatgattg gatttaaaaa tggacaaaat
    10501 aaaaaatagt agcagccgag aataatttta tagtgtcact gtggcggaaa tagaagacgc
    10561 aaaggtggag gtaggaagcg tatggcgcac tatcgggacc ttgtacaaaa ctagaaagga
    10621 ctagtacgtg tgtggtgcga gccctaggga ggaacaggat aaccgcctgt gtgtaggttg
    10681 ctattacata ttagatcact ctttgagtgg tctttttatt tacataaagg aggctacata
    10741 atgagaaact actggtatat atcgctaact aatgaatatc ctcgaaccat tgatgattgt
    10801 tcagtgcgtg ttgtgcgttc tgtccaaatc aaaaagaagt actccattgt tgaaatgacc
    10861 agagaagcta cgccaaaaga gattgataaa tgcaaacttc tttattgcgg tcatggtttc
    10921 tatgatgaac caaacattca aaataatatt aacaagaatt tgagggatta gaatgcaaga
    10981 aatggcttaa aaatctccaa tcaggacaaa tcaagttaga caaagtttcc gatttaaaga
    11041 tattgattga agctgattta atgctaaaag atattgaaaa ttagaaaaca aaactcaacc
    11101 taagaagatt gcgaggtggt gtgtattgaa tggcaagaca acgtgatcca agacgtgatg
    11161 aagccaaaag aatttggtta gaatccaacg gagaaaagca gttaaaggaa attgcatctg
    11221 aattaaatgt ttcagattct caggttagaa aatggaaatc gcaagacaaa tggagcgctg
    11281 aattgaaaag taacgttacc aatggcaaaa gtaacgttac taatcaaggt ggcgctccta
    11341 ttggtaatca aaatgctaaa ggtaacaaag gaaacagcag agcatcaccg ccaaagagaa
    11401 ataagaatgc tcttaaaact ggtgagtatg aaacaatatt ttttgacacg ttaaccgata
    11461 atgagaagga catctattct agtttgaatg atgatccttc ttttgctttg tccgaagaaa
    11521 tacgacttct taaaataaga caacttcgaa tgatgaaaag aatccaacaa gctgaagctg
    11581 gactaaatga tgaagaagtc gaacgattgc agcagctaag aaagattaaa actccgattg
    11641 aaaaaaatgg taaaaagcta gaaatcaagc gtgaggttat gcaagatgtg cagattagca
    11701 gaaaaaaaca tcgcaaaatt gatgatattc tttcaattga agattcattg actcggatta
    11761 gcaaccagtt agctaaagcc atcaagcaaa tgaatgaact ttatatgaat gaatacagaa
    11821 ctgatttaat taaagctcag actgataaga tccaagctga gacaaatgaa attggcggaa
    11881 ataattcagg tgaagaaata gaagaatgga aacaggcagt tttaaatgcc gcaaacaaac
    11941 gggcggtgaa agaaaatgaa taatgaattt attccttttg ctgatattgg ttctgccatt
    12001 gattattact atgataaacc agtagctttt tgccaagata ttttgcattt gaatcctgat
    12061 gaatggcaag aaaatgtttt aaatgattta gctgaatttt caaaggtttc tgttcgttct
    12121 ggtcaaggag ttggaaaaac agcattagaa gcaggagcaa tactttggtt cttaacgtgt
    12181 cgaccctacg ctaaagtaat agcaacagct ccgacaatga agcaacttta cgatgtactt
    12241 tgggcagagg tagctaaatg gttaaatgat agcttgatca aaaacttact gaagtggaca
    12301 aagaccaaaa tttatatggt tggtgattca gagcgttggt ttgctacggc tagaacagcg
    12361 actaaaccag aaaatatgca aggttttcac gaggaccata tgttgattgt ggtagatgaa
    12421 gcttctggtg tgtctgatcc aattatggaa gctattcttg gtacgctatc aggttttgat
    12481 aataagctgt tgatgtgtgg aaaccctaat aatattgaag gtgtctttta cgattcccac
    12541 aattcagacc gtgataaata cagagttcat aaagtatcaa gctatgatag taaacgtaca
    12601 aacaaagaca atatagaaat gattcttaaa aaatatggaa aagaaagtga tgttgctcgt
    12661 gtccgtattt ttggagaatt tcccaaaggt gcgttggatt catttatcag tcttgaaacg
    12721 gttgaattgg ctacagaaaa acaaattagt gattctttag tcaataaaac aacggttgct
    12781 catattggtg ttgacgtagc tcgatatggt gatgattcta cgattctctt tcctagaatt
    12841 gctaccaggg cattggagta tgagaagtat tcaaaacgta gcactatgga aacaacagga
    12901 tatgtcatca acatggccaa gaatctaatg agtcaatatc cgagtattga taaagtgatg
    12961 attaaagtcg atgacactgg tgtcggaggt ggtgtaaccg accgcctaga agaacttata
    13021 gaagacaagc attatccttt tgaggtgttt ggagtgaata acggttcaac atcagaagac
    13081 gatttttacg ataatttagg tactcaacta tggggaaaca tcaaggaaat gttagaagaa
    13141 aatatgacag caaatcttaa cggagaacag cctgttattg aattgccttc tgatagttcg
    13201 ttaatcaaag aattaagtac tcgcaaattc aaaatgacaa gtagaagtcg tatacgttta
    13261 gaaagtaaag atgatatgaa aaagcgaaat attggtagtc ccgatattgc tgacgcactg
    13321 gctttagcgt tttatgagcc accaagtcac tatcaattta ttcaatttta ggaggtgagt
    13381 ttttgattag tacagtatta tctttagaga gatataagaa gctacgtgtt aaatatgcaa
    13441 cacaaattga agatggaatg tttgatccga atggttttat agaatatatg aaaccatttt
    13501 ttgctgatcg cgaaagaaaa tatctagctt atactagcga aaagaatgaa atagacaata
    13561 gaccaaagcc taacactgat attgtaaaag ttaataataa acttcatgct ggtatgtatt
    13621 caattgtcgt agaccaagca gtcaatcatt ttactggtat acctatcaaa tgggattacg
    13681 atgtatcgga acaaaaaaga acactcattc aaagattaaa agataaattc ttaaaaaatg
    13741 atatagaact tccaacagtt ccagaagctt ttaacaaatt aacaagcaat cttgattcca
    13801 tgagattcgc aatgcttgat tctgaaactg caacttttca aggagcttgt ggagtagctt
    13861 tccgattgtt agagcctgtg gaagaagatg atggttggaa gttaagagca agtaatattg
    13921 aaccttggag agcagaaaga tatggaaatg ccggaatcta tatcaaagaa aagtatgact
    13981 cttaccagaa aaaatttttt caagaaatga aagttatgac aagaaataaa attctgacat
    14041 atgcttgcta tggtgatttg aattttgtta caagcggaac gttcaaaaaa attgatgaga
    14101 ccgataaccc tttggggacg attaccttgg cagaatttaa aaataatacg aatcgttatt
    14161 gtgattttga agtagctgag gaaattggag atgcaattga tcgtgctttg tctgatcaac
    14221 aaaacgaaat cgaacaattt aagcttgcgt acatgcttgt tactggcaca acaatgagca
    14281 aaggcactgc taaagaaatg atgaatcagc tagggattat caacttaaaa gaccctactg
    14341 caaaagctga atatgtcaca aaaaaattag caaaagattt caatgaatat catatggatc
    14401 tattgaaaaa acagttttac accatttgta aagcaatcga ttttaacgat gaggtgttta
    14461 aatcaaacag ttctggagaa gctcgcaagt ggcaaatcat tagcctagaa gcgaaaacaa
    14521 atactaaaga gcaatatttt agagaaggat tgaaagaatg cgcagaaaca attgctgctt
    14581 ttcttaagtt tcatgacaaa gtagaaattg agcctgaaaa aattattttt actttctcta
    14641 gatctttgcc aactgattta agttatttag ctgaagcttt acctaaactt gcaccatacg
    14701 tatccaaacg aactattcag agccaaattc catttgtaac agatgttgat tatgaaaatg
    14761 aaatgatgga attggaaagt ggaagtgctt atccagatag tgaatacaat tttggcggag
    14821 gtggcaatag tgacgataga aacgaagtat tggaccaaac gtcgagaact ggaggatcaa
    14881 gcaaggctca aacaagaaaa tcagacactt aaaaaattaa ctagtgtatt tcctgaagca
    14941 ctgaaagaga tacaagcaaa actattatca caagctgact tacacaatat cacttatcca
    15001 gaaatgatgg agttttacag tacaagtaat cagaaaaaat atcgtgaata tgtggaaaaa
    15061 aattataagt cattaaaaat gtatgatgca aaatacaaag agtttatcga tgaatttttt
    15121 ccaccatttg actatgcaaa agtcaatcgc ttattacaaa tacgatcaga tgtatttaaa
    15181 attcttgcag aatatgcgat ggatgcagat gtgaatcaat atttttctga tcgcttagag
    15241 gaaattcttc aaagaacata ttcttctaat gctaatgttt ttgttcaact tttaaacgtt
    15301 gatataccaa attatttacc agaaaatgaa attaaacatt atttgaacta tccatggtca
    15361 ggaaagacat tttcaagaag actttgggga aatatttcat cgcttgaaca gaaactctct
    15421 aatgctattg taaaaagtgt tgctagtgga gaaggcgtta tacacgcatt aaacaccatg
    15481 agattagact cagaaatttg tgacatgttt aagttagaag aatcaaagta taacaaagcg
    15541 atagaaaatc tcgttcgaac ggagtatgca aaatttgcac aagatggtat tgaaaaatca
    15601 tatttagaaa caggtattga ggaatacaac gtattgactg caaaagatga gagagtttgc
    15661 cggatttgtg gaggaaaggc aagtaagaat ccctataaac tgaaagatgc tgtcataggt
    15721 gaaaatcgag cacctttcca tagtcgttgt agatgtacgg atgttcctaa tttaccaaaa
    15781 ttaggaaagg atattgatga agaatatgac cgtttatttg gcgatttatt agatgagttt
    15841 gcacatgatt cttttggaat taatttgaaa cggaggaagt agaatgaaag atttttttga
    15901 agcagtacta acaattaatg taaatgctga tattgcagaa gcctacaaaa cagctattga
    15961 gtctgagaac catcctaatg gcttgagaga ccattggaat ggcaattatg cctacgtggt
    16021 tattggcgat caaactgtta attatcaaga taatactcca gttgataaga ataccgttaa
    16081 tttaacgatt caattattat ctcattcatt accaaattta aaagaaacag ttgattggta
    16141 tgaaaagatg ggatgtattg ttgttagaac tgactacaaa gaaggaaagt ctagtaatta
    16201 ggctttttta ttttgtccga aatgacgtta aactagcgca atactgggct tggttgaatg
    16261 gtggggcgca actattaaaa ctcaaagcaa tgcggggcgt gaaaacgaat cgtggggcga
    16321 aaggagaatg agcatgaaac acaaatcatt aatgccaatg aatttgcaat actttgccga
    16381 aggtgacgat caaaagtttt cttttgatga cttcaaatct tttgtggaat ccaatgaaga
    16441 agctcaaaaa tttattcagt cacaatctca aagtgttgcc gacaaacaat tggaagcttg
    16501 gaaacaaaat aacttagata aaattaaaca ggataccatc aaggaatatg aggaatctaa
    16561 gaaaaacaag tcacctgagc aaattcaact ggaaaaacta caagctgaat ttgaagcaga
    16621 aaaagcgttg cgtgtgacaa gtgataataa agcatttgtt gcagaacaaa ttgctggatt
    16681 agaactagat ggagagttaa aagagtctat ttctcaattt atgctaaata atcttgttag
    16741 ttcggataca gatttcacta agaatgctgt tgaaggtttt acaagtgttt tgaatgcaat
    16801 taatgagaaa catgcagatg cattaaaaga actacaaatg aagtctgcat ttggtggaac
    16861 tcaacaatcg aataaccagg ttcagcagaa caatgaaaca ttaacaaatc cagaagaaca
    16921 attaggacaa attcttcaac aatttaacta ggagagtgaa aaattatgaa aaaaacatct
    16981 ttaaataatt tagagtattt ggatatttca ccagcgatta atgctatgca agtaccaaat
    17041 acaccttttt taagctattt acttggtgct ggaaaaacag agccagcaaa ctcgacagaa
    17101 attaaatggc gtgaatatga tatcaacaac gatgattctt ctgaaaaact tgagggcgga
    17161 gaatatccag atgctgaatc aggtcgaact tggtttaaca actatactga aatttttaga
    17221 aaatcaacct ctgtatctgg tacattagat gctattaatg tgaatggagt cggaaatgaa
    17281 ttaactaatc aagtagcact acgtggtatg gaaatgaaaa ttgatttgaa ccgaaaattg
    17341 attactggtg taaaagctga tgaaaatggt tctaaaggtc gtcgaatgaa tgggattttg
    17401 aacttgatca attcagcaaa taaggcagaa acagccactg cgggtgcagt aacaagaaaa
    17461 gatatcgata ctttatttaa attgatgtat gaaaaaggtt atatgggaga aaaactatgc
    17521 ttgatttctc cagatatgca ggagttaatg actgatgagt tagatggaaa atcaacaaaa
    17581 attgttcagt tcggggaaag agtaactttt ggattgcaaa ttggaaatat cgtgtctaat
    17641 tacggtacag gtattgctct actagaacca tcattgccaa aaggaacaat tgccgcaatc
    17701 gatactaatt atgtgaaact acgtccatta cgtgaatgga gagcagaaga acttgcaaaa
    17761 acaacggatt ctagacgtat cggtcttgta ggtgaatact ctcttgaata caatgcttca
    17821 aactctgggg caattttaaa tttaaagtct gaataaaagg gagttagtac tccctttttt
    17881 gataggagga attacagtgg taaaaaaaga tgaaactaaa aaagatgaag tcgtgaaata
    17941 tagagtaggt aaaactaaaa attttgttgg gtttgttcat cctaaaactc gtagatttat
    18001 cacagcagat tcaaataacg aatttatcat ttctatagat gataaagaag caattgcaat
    18061 tttggaagat gcaattgatg ttaatgaaat ttaggaagtg atctgatgga tgaatcgcta
    18121 aaaacggaaa tcattgagtc tacaaaagaa gattttccag atttgagtga agaacgcata
    18181 actaatttat tagaaataat tttgctagaa attgaatcat acaacacttg taaaaatgat
    18241 atttcatggg aaaagttaaa aagcgtgatt agtgaagtgt tgtataaaat aataaaaaat
    18301 gaatcagaaa aaacagtatc ttcagttaga cgtggcgata caacgattag ttatgcttca
    18361 acaacaaatg atgttagtga gttacttcta ggctatggtg atttgatacg aagagttatt
    18421 ggttgtggag gattggagtt tttttaatga atgaagcaga tattttagaa actacttatg
    18481 aagatagttg tattattgaa agactgacgg acattgaaga ttctaataca aatattacta
    18541 ttcaagatta caaaaaagta tatgataatc ctatttcttg cgctctttca caaggtcaaa
    18601 tcgatggact agcagtcata gaagatggag agatggtaaa tgtttcaact gacacatata
    18661 aattatttgt tcatcctaag attaaactaa aaaaaggaga tcgaataaca ataactcaaa
    18721 aggccagtgg cttaattttt tctctatttg ctactaagcc tttttactat cctagtcatt
    18781 gtgaagtgaa tttgatagga agtgagaaaa atgggtaatc tcaaatatga atcaaatgca
    18841 gaaaagatca ttgagaattt taaaaatatg actgtaattg ctcaaaaaga aggaatatcc
    18901 ttcgttaacg attcaatgaa taaagtcgtt agtttagcta aaccattaac tcctgtaaaa
    18961 tcaggtaatt taaggcgagg atatcgtgta gtaaaagcta gaaaactatc aagcggtcga
    19021 attgttggag cagttataaa caatgaacat tattttaaat atgtagaaga aggtcatagg
    19081 actaaaaatg gtggctttgt caaagggaaa ttcatgttaa ctcgtgcaac gaatcttgca
    19141 aatatgtctt atattcctcg aagatttaaa caaatggcaa taaaaatcgt taagaaagga
    19201 aagtaacatg aaagatgaaa tcattgctgc aatcagtagc aaattaaaag aaatctatcc
    19261 tgatgggaca atatatcttg attcagttat gcagtcaact aaagattttt atttcgtttt
    19321 atcagtaatg gaatctggaa ctgaaaatgt aggaattgat attcaaaatg tttctttctt
    19381 aattgatatt gcattgattg ataataaacc taatagaaat ttaattaatg aattagtctc
    19441 acgttgtggg acttttttta atacgattac aatcgatgag caaatattat ttccaaaagc
    19501 ctatttacct gatgaagcag atggtgttca acatattcgt tttacattag aatttccaca
    19561 atatattgaa tggagtgaaa gataaatggg agaaaaaaga agtaaaaccg gaattatttc
    19621 tgtcgaaaaa cctacttggt ttcctttgga agatgagaca gggaattttc cggtatatgg
    19681 tactgcgttg ccaatgggaa cagcagtaag tatcaaacca acagctaatt atgaaacaac
    19741 acaagattat ggggattcag tggttcaaga tcaatttaca gcttttggtg gtgcagaagt
    19801 tgaactggaa gcaaatggat atactcataa agttttatct acaattactg gagggaaaat
    19861 tgttaaaggt ggtgccttgc gttctggaga agatattgcg caagatggtg cgtttgcata
    19921 tagacgtaaa aaatcgaatg ggaaataccg ttatacggtc ttttataaag gacagtttgc
    19981 tctagattca gatgaaacat caacgattga aggaagtaaa gtaagtttta ctcatccaac
    20041 ttggaagggt tcatttgtag atgtaccagg acttggatat atgtattcag ttgatgaaga
    20101 tgatgaaggc gtggataaag caatgatcgg aaattggttt acaaaagtag caattccaat
    20161 tgaagaagca gaactttcag gaggtacaga ataatgtcaa aatatcaaac aacgattaaa
    20221 ttaacgaaaa aagatgaaga aggtaaatat gagcaagtac aatttaaatc tgctgaattt
    20281 ctaccaggcc cagtcgtaga agaagcagca gaagtaatgg agggaatgca aaatgctgta
    20341 gatggaaaat cagtatcaga agcattaagt cgagcttatt catttattgc agatattttg
    20401 tttgaaggac agtttactgg tgaagattat cgtcaaggga tcgatgctcg agaaattgct
    20461 tcgttgacag gtaagttatt aaaatctgtt actgcaggct ttgatgaaac ttatacagaa
    20521 acgaaaaaaa agtaagcgaa gctctcaaat atcctttttt taaacattcg attacttatc
    20581 gagaattaga tttaaagacg caattactcg aagcaggttg gacgttacca gaaattgaac
    20641 gtactgactt tgacgagtta atgcgtcttt ttgcttttcg agatgcagta aaagagcatg
    20701 aggatgttga gtactacgat aacttcaccc aattttagga ggtgatactt tgaataacga
    20761 tgacctaatt ctgaagatga tactagatga atctggtttt actgccggta tgaataatgc
    20821 tgtcaaaaag ttgaactctt ttgatgaaac aatcgaaaga aaaagtagaa atagtggcag
    20881 ttcattaggt agtatttgga aaatatttgc tggaagtttt ctagctagcg gagtaactag
    20941 aatcgtagga gctggctttg atctaatcaa gggttccata agtggagcgg ttgatcgagt
    21001 agatacgatg aataacgctc tacgaaattt ccaaaatatg ggatttagta attcagaaat
    21061 tatgaagaat atcggaaaga atgggctttt atctcaaggt attcaaggac ttcctactgc
    21121 tttgaatgat gcgataagtc atgttcaact tcttgcttct tctacaggtg atttaactcg
    21181 ttcaactcaa atatttaaag ctttaaatga tggaattctt ggtttcggtg gttcaactga
    21241 tcaagttaat gaagctgtta ttcaattatc tcaaagtttc tcaaacggaa aagtagacgc
    21301 acaaacttgg aactcaatga tcaacgctca acttggacct actctttctg ctattgctaa
    21361 aaagatggga attacaatgg gagatctgaa agaaggttta tctcaaggta agatttctgt
    21421 tgaagaattc caaaatcaat taatagaaat ggataccaaa ggtggcggag gacttaaatc
    21481 attaagtcaa atcgctaaag attctactaa gggaattaaa acctctatac aaaatgcaaa
    21541 aacagctgtt acacgtggtg ttggtgaggt aatagaagga ttaaataaag cattagtaga
    21601 ttcagattta ggtggattta agggaattat tgataaagtg ggcagttcaa tggaatcgtt
    21661 cttaaaagta attgctgcaa atattcctac agcagtatca tttttaagta atttatttaa
    21721 cgaaattcaa aaatttggtt ctgctttgaa attcatgatg ccctttcttg ttcctgcagc
    21781 taccgctttt ggagcgttca tgtttcaact taaaggtata ccagcaataa taaaaagctt
    21841 caataatttt aagaatgcca taattggcgt tggaaattca ttaaagatta tgggggcaat
    21901 agctgctgct aattcatttg ttttaattat tggtgcagtc gttggtgcaa tagctgtttt
    21961 cggttacttt atggcaacca atgaagagct tagaaacaag gttatatcta tttggaatga
    22021 tgtgaaagat tccgtaattg gtgtattaaa aaatataaag gactggggaa ttgatacttg
    22081 gaattctgct aaagaaatgg catcaaatgc agttgagggt gtcaaagatg cttggtcagg
    22141 aacaaaggaa tggttttcta acacctggaa aggtattaag gatggggcca caggtttatt
    22201 tgataaaaca gtagagactt caagaaatgc agtcgatagt gtaaaaaatg catggtctaa
    22261 tatgaagaaa tggttttctg atacttggca aagtataaaa gattcagcca gagaaaaatg
    22321 gaatggaatc aaaggttcta ttatgtcagt tgctggtcca ttgattacag gtataaagaa
    22381 tgcattttta catgttactt tttatctaga gaccttatgg aataatttag ttgagattgg
    22441 taaaaacgtc tttgagattt taaaaaatgt tatacttgcg ccggttttgt ttattacctc
    22501 catgatttct ggtggatggg aagaaacaaa aaataatatg attgctgttt ggaataatat
    22561 taaagaaagt gccataaata tttgggaatc tataaagaat atatttgtaa gttattttac
    22621 aaatatttat tttgctgcac tcaatatttg gacagggttc aagcttacat tgataaatat
    22681 ttggaatgaa gtggtaaatc aagctaaatc gatttggtta aacataaagt atttttttat
    22741 taatctttgg attgatataa aatattttgc aattcagaaa tggattgaat tgaagttttc
    22801 tattattcaa acttggatcg atttaaaata taatgccatt actacttgga ataatattaa
    22861 acagtttttc aaagatactt ggaaaaatat taaagatacg gcatacaata cgtggatttc
    22921 tataaaaaat accatgatta atacatggaa taacattaag gactctttct ggaatattgt
    22981 tactggaatt gttaattctg ctgaaaatgc atggacaaat ctaaaaaatg gtgtttcaaa
    23041 tgctattaat cgggtaaaag aaatctttaa ttcgttaagg gaagtcaatt tatttgaaat
    23101 tggcaagaac atcattgatg gacttataaa tggtgtaaaa gaaaagtgga atgctttgaa
    23161 agatactatc aaaggtattg caggtaatat caaaaattgg attaaaggag ctttagatat
    23221 tcattctcca tcaagatgga tgcgtgatat ggttggtaaa aatattgttc aaggtattat
    23281 cgttggtatt gataaagagc aaagtaagtt agatcaaacc atgacaaatt tagtaaaaac
    23341 accgtctgtt caacctgtag taaatggaat aagtcaccta ccaattacac aaacaaagca
    23401 aaatatatct gctagtgaaa caaaagaaat tcatttacat ttaaatgttt atggagattt
    23461 acctgattca atggttcgaa agattactac aaaaattaaa acagaattga caagacaaat
    23521 gaaacgagat gctggtgcag taggaggaac attatatgca acttaagaga ggacaatttt
    23581 ttattaatca acattattct tctgaattta atgtgtatat tcaaaacagg cctgcttctg
    23641 tttcagctag tcgagtaatt gaattgagag agcgagaagg aaatgattct atcattattg
    23701 ataaaggcta ttacaaaaat gtgactagaa agattgagtg ttactataaa gcaccttcaa
    23761 ttgatatggt gcaggagtgg gaagatcgaa tcactgaatg gttagatatg tcgtcttata
    23821 gtgattttat tctttactat gatgaacaat atatttatca agctgtagta atagaaggac
    23881 ctgaatttaa aggaacaaga aaaacaggaa atattgtccc ttttgaattt acagtgagta
    23941 ttcgaccatt taaggaaaat tacaatggta gatttactat tcgacaaaca gaaacttttg
    24001 aaatttataa cccagagaag tattcttcaa aaccgcttat taaattgagt ggttctggag
    24061 atgcttcttt ttatattaat aaggataaat atgatttgaa atcgttggac agagaattat
    24121 ttatagattc taaattagaa gaggcttatc gaaaattaga tggtaattta gaacatcagg
    24181 atcaggtcac cttattttta gattttccat ttttatatcc tggaaaaaat gaaattaaat
    24241 ggacgaaaaa tattcattca tttgaaataa tgcctaggtg gtggagaaaa gtatgaaacc
    24301 aagaatatat agtcctactg aaacagattt ctcaacgaat ggcttaggaa ttttaaagga
    24361 ttgtacaaga tgtgaaatat atgaagtagc taatggaaaa tatgaattag agttggatta
    24421 tcctttagga actagatttg atgaatattt tgaaaatgac tatcaaataa aagcaaagcc
    24481 aaacgatcaa gaagagtatc atatcttttt tattgatgat aaagatatag atactttttt
    24541 aaatacagta actatttatg ctcagagtcg tacaaatcga cttggaagac gggtagtcac
    24601 tcttgtggaa gtggactcta aaactggtca agaagcgata tcaattattg aaactaaaat
    24661 ggataaaaaa tctgacatac gactttattc tgatattacg gctgtttcta gcacaatctt
    24721 tgaagcgaga aatgttttaa attgtattgc tggtgaacaa ggatcattgc ttcaatattg
    24781 gggcggagaa attaaacgtg aaccatttaa gctttctttg ttaaagcgaa gaggtcgcaa
    24841 taatgttgga acgattcggt atggaaaaga tatgtctggt ttgaaggtca aattagattg
    24901 gacaggtata aaaacaagaa ttattccata tgctgatcct caaagtgaag taggtacgac
    24961 taatcgaatt tatggttcgc cagtagatag tgcctatatt aataactatc ctgatgtcta
    25021 tacagaacat gttcagttta cagaagaaca aggagtaaaa gacattaaga gcttaaataa
    25081 aatagctaaa aattacttta aaacgatcaa tcctggctgt gataagccta aagtttctat
    25141 tacggttgaa tttgataagt tgactgatag tgaagaagcg aaagaatttg cgaagattag
    25201 aaattatggt ctgtttgata catttaaaat atatcataaa aaatataata tttatcttga
    25261 atcaaaggtt agtggactac aatacgattc tttatctgaa aaaactttga aattagaagc
    25321 aggagacatt caagttgctt tttatcagca acaagctgta actattcagg ataaattaaa
    25381 agattatgca acgaataatt atatgagtga ttttaatgat tatgtttctt caatgattac
    25441 aggtcaaggc agtgcaggag gatatgtagt tttatggcca aaagaaaaac cttccaacat
    25501 ctttattatg gataatccag atttagaaaa ggcaagagaa gtactaagaa tgaataaaaa
    25561 tgggattgct ttttctaaga aaggatggcg ggggcctttt aattcagctt ggacattaga
    25621 tagtatattt aatgccaatt ttatacaaac tggattaatc aaagcagata tctttcaaaa
    25681 ttcttttaac aagactggag atgtattgaa attagttaat ggactactcc aaatttggaa
    25741 caacaaaaag aaaataatgg agttaactaa aaaaggaatg gaattttgga attctaaggg
    25801 ttcaattgga acgattggaa caactgattc tgttggtaat ccttttcctg gggcttctac
    25861 tccaacccct attgaagata attctttagt tattcgtaca aatggagacg gcaaatatat
    25921 tttgatttct cctaaagtag gaaaaggatt agttttatta ggaaatggta aagcaattta
    25981 ttttggagac ttagatgtac aaggaaaact tacagttaaa ggaaaagaaa taattcctgg
    26041 acaaggtggt ggtccatcgg gaggtggaga atctactggt gggtatccta gtgaattaaa
    26101 aacagatgca gaaaagagag cttggagaat
//
LOCUS       DACCVH010000031        25285 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.031, whole genome shotgun sequence.
ACCESSION   DACCVH010000031 DACCVH010000000
VERSION     DACCVH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.031"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(26..1957)
                     /locus_tag="IVV98_001387"
     CDS             complement(26..1957)
                     /locus_tag="IVV98_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP7807054.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="IVV98_001388"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="IVV98_001388"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP7807055.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="IVV98_001389"
     CDS             complement(2886..3638)
                     /locus_tag="IVV98_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7807056.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3798..4007)
                     /locus_tag="IVV98_001390"
     CDS             complement(3798..4007)
                     /locus_tag="IVV98_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807057.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4018..5345)
                     /locus_tag="IVV98_001391"
                     /pseudo
     CDS             complement(4018..5345)
                     /locus_tag="IVV98_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5710..6297)
                     /locus_tag="IVV98_001392"
     CDS             complement(5710..6297)
                     /locus_tag="IVV98_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP7807058.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="IVV98_001393"
     CDS             complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="IVV98_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP7807059.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7877..9166)
                     /locus_tag="IVV98_001394"
     CDS             complement(7877..9166)
                     /locus_tag="IVV98_001394"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP7807060.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9320..10252)
                     /locus_tag="IVV98_001395"
     CDS             complement(9320..10252)
                     /locus_tag="IVV98_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807061.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10409..11068)
                     /locus_tag="IVV98_001396"
     CDS             complement(10409..11068)
                     /locus_tag="IVV98_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP7807062.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="IVV98_001397"
     CDS             complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="IVV98_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP7807063.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12109..12399)
                     /locus_tag="IVV98_001398"
     CDS             complement(12109..12399)
                     /locus_tag="IVV98_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807064.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12808..14613
                     /gene="glmS"
                     /locus_tag="IVV98_001399"
     CDS             12808..14613
                     /gene="glmS"
                     /locus_tag="IVV98_001399"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP7807065.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14685..16040)
                     /locus_tag="IVV98_001400"
     CDS             complement(14685..16040)
                     /locus_tag="IVV98_001400"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP7807066.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16064..17233)
                     /locus_tag="IVV98_001401"
     CDS             complement(16064..17233)
                     /locus_tag="IVV98_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807067.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17230..18117)
                     /locus_tag="IVV98_001402"
     CDS             complement(17230..18117)
                     /locus_tag="IVV98_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP7807068.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="IVV98_001403"
     CDS             complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="IVV98_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP7807069.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22197..22718
                     /locus_tag="IVV98_001404"
     CDS             22197..22718
                     /locus_tag="IVV98_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP7807070.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23417..23974)
                     /locus_tag="IVV98_001405"
     CDS             complement(23417..23974)
                     /locus_tag="IVV98_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807071.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24153..24764)
                     /locus_tag="IVV98_001406"
     CDS             complement(24153..24764)
                     /locus_tag="IVV98_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807072.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24877..25134)
                     /locus_tag="IVV98_001407"
     CDS             complement(24877..25134)
                     /locus_tag="IVV98_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807073.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
BASE COUNT         7078 a         5494 c         4386 g         8327 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa ataaaaaacc agtcagaaag actggttttt tatttttttg
     3781 tctatcatca agccgtttta tcgtttttta ttttcgcttc ttgttttttt catataaaca
     3841 gaagcaggtt ttctttcctt atgaagaaga taataataaa gtcccatccc gccaaacatg
     3901 accaaaaaac cgatgactga tcgaatagga aaattaggaa caaaaaagag acagacggat
     3961 aataatgatg ccggaaccat tattcgataa tagagttgtt tatccatttt cttcacctca
     4021 tattttttgt aaagtaatca attgttctaa ttctcggtaa tctaaaaatt gcacacgcag
     4081 atgctgctca cctttcttga catcgaattg gatacttcgc cgctttttct ttattcgttt
     4141 gaaggtaaca tcagagagtc tatgtttgat ttcctttaac ggtaattctg acagggattc
     4201 tgaaggaaca tagattctta aggataaaag atactcttga tatttttcat ctgttacctc
     4261 tacttctaga tattccctaa tataataaca ataagcttcg attccattat ccaaagcaac
     4321 agtcggatcg ataactttat agcacatcat gcgtgatcga ttctcgtcaa cccaaggaaa
     4381 atacgcctga gcatttagtg ttccgcgaac acgcctttct ttataatctc cttgttggat
     4441 atcataactt tttgttacaa aaaatgaagc attcttttta ggaacaggtt gcatttgtgc
     4501 attctgatac tggacagatt ggatcgtatg gtcagtgtaa atgtattcaa cgaatggcgg
     4561 tttcaataaa ccgacaccat tgtcccaagc aagatgatca aacccaagct ggtccctaaa
     4621 ataggattga aacatttgat tgtttggctt ttgccagtta aaggggtctc gataaagctg
     4681 gatacatatg acttcgtttt ctaattcctt cactttttct acttgttgga tgtcgagaaa
     4741 aatcggttta gggatgattt gatgataata gcgactataa tacatttccc aacacgaagt
     4801 gaaacataaa ccttggtaaa aaagatcgta tcctggaaat tggttgcaat cgactactac
     4861 ttccccgttt tgttgtttca ttttaggtaa atgttcgatt tcatcctttt tctcaaacaa
     4921 tagccgttga gagatctgtt ttgtattgtg atagataaac tcgctataag ctcgcatata
     4981 ggcgaacacc ccatgagcaa tcattttttt ctgaatgaag tctcgaatca aaaattgctt
     5041 ttctttgaaa acagagatag acaatacatt ttttatcaat aattgattat cttccaagcg
     5101 aaaactacat tcgttctcgt catttcctac aactaaccaa ctttcgtctc ttaccgatgc
     5161 tagcattatt ttttcttgaa gctttcgaag atcatacgga tccgcttgtt gtgtgaaaga
     5221 gcggataaat gttggctgga tcaacagacg tgtcaaaata gcccaatcgc ttatttcctg
     5281 tttttttctt cttcatttaa gtctgtgagc tggatagtca tcaataattt atcttcgcca
     5341 atcattttct cacctctttc aaatcttttt ataatttaat tataaccaat gataaagaaa
     5401 aactaaaact ttatgtctta gaaaccaatt tggacgatta catgatagac taagtaaaaa
     5461 gaaacaaaga ggtgtttaca atggggttga aatttgaacg tacagataat ttagataaac
     5521 ttttcgaatc atttgctgtc gatccggaaa aaacagttgc accaaaagaa gagatcgatc
     5581 gatttctaaa accacagcca caaaatgaaa agaaaaaaga caagaaacaa aagtaagtta
     5641 agctcaaaaa aagacttacc agccaaactt ttatgaaaga gtttgactgg taagtctttt
     5701 ttattctttt tatgattcaa ttgcttgttc gattgctgcc cacgcttctt cttttccctg
     5761 ttttgtaacg gaagaaaaga gaataaacgt gtcattgcga tcaaaatcca acgctttttt
     5821 gatttcgctc tcatgcttgt tccatttacc acgagggatc ttatctgcct tagtggcaac
     5881 aacaattaca gggatatcat aatacttcaa aaattgatac atctggatat cttcttgaga
     5941 aggcttatga cgcaaatcta ctaaagaaac gaccgcacgt agctggtctc tagtcgttaa
     6001 atatgtctcg atcatctttc cccattttgc tcgctcagtt ttggatactt ttgcataccc
     6061 atatcccgga acatcgacaa aatgtaatgc gttctcgatc aaataaaaat tcaatgtctg
     6121 ggtctttcct ggcttaccgg aagtacgggc taaattcttt cgatcaatca atgtgttgat
     6181 aaaagaagat ttccctacat ttgatcgtcc tgccagagct atttctggca attgtgtatc
     6241 tggatattgt tttggtgcca ctgcacttat gataatttca gcttgatgga ctttcatggt
     6301 ctctctcctt aacaaggtga tgaataaagc aagcggctgt cgcaaaagcc aaaatgactt
     6361 ttacggcagc ctcttttcat caacccgctt ttttctctga atctttatag attactgttg
     6421 gctcaccaga caattcagct gcttcttttg tgataatcac tttttcgatg ttttcatttg
     6481 aagggatatc aaacatcaca tccatcatga tttcttcaat gatggaacga agtcctcgag
     6541 caccggtatt gcgttcgatt gcttttttcg caatggctct caacgcttca ggttcgaatt
     6601 caagttcggt attatctaga gaaagaagtt tttgatattg tttgactagc gcatttttcg
     6661 gctcagtcaa gatccgtacc agatcatctg ttgtcaattt ctctaaagct gccataacag
     6721 gtaatcgtcc gataaactca gggatcaatc cgaattttag taaatcttca ggaatgatat
     6781 gctgcatgac actttcgtct tcagaaagtt tttggttttg tgtaccaaat ccaatcgtct
     6841 tttcgcccat acgattcttc acaatcgttt cgatgccatc aaatgcacca cctacgatga
     6901 acaatatgtt cgtcgtatca atctgaataa attcttgatg tggatgttta cgtccgccct
     6961 gaggtggcac acttgcaaca gttccttcta gaattttcag caaggcttgt tggacacctt
     7021 cgccggaaac gtcacgagta atagatacat tttcgctttt acgcgcaatt ttatcgatct
     7081 catcaatata gatgatccct ttttctgcaa gttccacatt gtaatcagca gattgaagca
     7141 atttaagcaa aatgttttct acatcttccc ccacataacc agcttctgtc aaacttgtcg
     7201 catctgcgat tgcaaaaggt acattcaatg tttttgctaa tgtttgtgct aaaaatgttt
     7261 taccagaccc tgtaggtccg atcaagcaga tattgctttt ttgcagttca acatcatctg
     7321 tgttttcttg tgcttgctga ttgacacgtt tatagtgatt gtatacggca acagctaacg
     7381 agcgttttgc gcgatcttgt ccaatcacgt agttattcaa tacttcaaga atttctagtg
     7441 gtttagggac ttcagtgaat tcgcgtacag cttcttcata aaattcttca tcaatgattt
     7501 ctttacatag gtcgatacat tcattacaga tgtagacccc tggaccagct acgatctttt
     7561 tcacttcttc ttgggttttc ccgcaaaaag aacagcgtac ggtctcattg ctacttggat
     7621 tgtcatacat ggtcttcacc ccttaacttg caaaaagtat gcaagaaact atcaaagact
     7681 ttacagtctt ttactatcat aacatagttt agtaaaaaga aaaagtgttt aacaaaggat
     7741 caactgacct atacctttgc attttttact cttaacaaaa aataaggaac tgtgacaaaa
     7801 tcgtgtcaca gtcccttatt tcgaataaac aattttctag aagtagcttc ttcagaaatg
     7861 atttattact tgatttctat tctttcgctt ctgtcgctgt acctgtgatc aattcgattg
     7921 cttttttcat tgtcacatca tgttccagca tatcttctgt caacacgcgt ttgatttgtt
     7981 cgattggcat gttgtatgtt tctgataatt cttggatttc tgcattgatt tcttcttctg
     8041 ttgcttgaag attttcagca gctgcaattg cttcgatcac aagatttgtt cttgtgcgca
     8101 tttctgcttc accttcgaat tgtttatgca agtcttcttc tgtagaacca gttaattgat
     8161 agtacatttc aggagagata ccttgacgtt gcatgttgtt caagaattcg tccattgaac
     8221 gatgtacttc atcatgaacc atcacgtgtg gcaattcaac gatttctgcg ttttcaacag
     8281 ccatacggat cgctgcttca tcttttgcat cgtccgctgc tttttctttt gtttctacta
     8341 attctttgcg atatttttct ttcaattcgt ctaatgttga tacttcgtca tcaacatctt
     8401 ttgcgaattc gtcatctaat tcaggcactt cttttgcttt tacttcatgg attgtcactt
     8461 tgaagactgc ttcttttcca gcaagatctt ctgcttgata atcttctggg aaagttacat
     8521 ttacatctag actttcacct gatttatgac caactaattg atcttcaaaa cctggaatga
     8581 atgagcctga acctaattca agtgagtaat tttcgccttt tccgccatca aacgcttcgc
     8641 catctacaaa gccttcgaag tcgattacta ctgtatcgcc attttcagct gcagcatctt
     8701 ctttgataac taattcagct tgtgcttctt gttcacgttt gatacgtgca tccacgtcag
     8761 catctgttac ttcacggtct tgtttttcaa caactagatc tttatattgt cctaatttta
     8821 cttctggttt cactgttact tcagcagtga ttacccagtc ttgacctttt tccatgcttt
     8881 caacatcgat ttttggttga gaaacaggat cgatgccagc ttctttgaca gcagcttcat
     8941 aagcttctgg taatacagca ttcaatgcat cttcatataa agcttcttca ccgtacatac
     9001 ggttgaatac ttgacgagaa actttccctt tacggaatcc aggtacgttc aagctttttt
     9061 tcactttatt aaacgcagtt gttaatcctt tttggatttc gtcttgcgca atcgtaaatt
     9121 ttaaaacacc atcattcgtg cctttttttt caaatgttgc agtcatttaa ttccctccga
     9181 gtttagaaat tcattttata catcaaaaac gtttcatgca tacctttaaa tagtacacta
     9241 accctttcaa attgtaaaca tattgaatgg atagaatcct tgtttttcat aacattttta
     9301 tctttttcac tgataaaatc taatggaaga agatcatttg ctgcaaaatt ttttctcttt
     9361 tttttaaaaa atcttgtttt tcatcttctg taccttcata catcgttttt cctgtacacg
     9421 cctctacagt cagttgaaac cagcgcttcg ggtcttcgat gtatgtatca tagacaggat
     9481 aaacaattgc agattgcaac gtgaattctt cttttaacac ggaactaagc agcgcatctt
     9541 cattcccgta acgatctgaa aatacacata attgctggta acttgcctgc tgctgcggct
     9601 ttggcagatc ttttggtatg actttgacta acttttcttc aatcgtcaaa tagaaaacag
     9661 gatggcattc gttcaattgc ctaagtgtct ccagtaattt tgcccttgct aaaatatgga
     9721 cctctggcga tacaataagt ttactcgctg tttggataaa ctcatgataa ggaagctgtt
     9781 cgatctcatc aatagacgca agctgacgtg caggttccaa cgaaggaagt tcctccgatt
     9841 tattgtggag tgccttgatc ttctgcctct ccatttgtcc ggataattct tctgcaaatt
     9901 ggattttttc aatgacccgc tgctcgaaag cttcataaaa atctgtactt gctatcaatt
     9961 ttctagcata taaaaaatct tgtgtactga ttaacaagtc aaaataaaat tcagcaaact
    10021 cctcattttg aagatactgt ttttcatgca agagtgcttg cttcaatgct tcttttttct
    10081 cgtccaactc gtaaagacaa aaaacaagca ggctattagc ctcaaagctt tctttcaact
    10141 cgtaagctcg ttgaaataat tcttttgcct gctgatattg ctggtttgct agtgcttgtt
    10201 gtgccactcg cattaaattc tcatattttt ctggaaaatc aatcggcttc acgcagtgtc
    10261 ctcctcttgc tcatattcag ctcatgttca atagtagcaa aacaaaaaaa gcatgacaat
    10321 taaaaataac tgaagcaccc tctaaaagct agattttaga tctgactttt agaaggtgct
    10381 ttcaactgtt actgcttttt attgctcatc agctgttgac ttcctggttg aacgctttga
    10441 tcagattgat cgtaacaaca cttgtattag tgaaaaaatc gcccagatgt tgctttttct
    10501 gattaaagac tgctggaaga taccctaaca tcagcaaagg aaattttaga atgaaccggc
    10561 aagcaccttc tctaactaaa acggttgacc agctaagttc ttcttcatca aagctgatga
    10621 ctcgaatacc aaagatcatt ttcccaatcg tttggccatg attgaatttc gtcaataaaa
    10681 taaaatacgc tagataaata agtaaggctg tgaatccgta gagactcaga taagaatctg
    10741 aaaaattaag ccaacctaga tttttggcaa taccaagtgt taaacgcgta atagctccga
    10801 tacacaaaag atcgaccaag aaggcaaaca ttcggataaa aaaacctgca tagaaatact
    10861 taggaaaatc atttgctttt ggcggttcat ttcttgtgtc cgtatacttt ttccatttac
    10921 gttgtttctt tttgatttct tcgggcgtca aaggctctct ttcaaaagag ctcagtacct
    10981 tttgggaaaa gttggagtca ggtcctacag caggctgctg ttgcttatct ttttcttgtt
    11041 ccttattttc atttgaaagc tctgacatgc ttactcacct ccgtaataat acattgcttt
    11101 tggtgattcc gctgtcccta gattctcaag aacggataag atctgactag tctcagaagg
    11161 cttcaatccc tggaattctg ctagtttact tcctaaccat gtactagcaa acccagatgg
    11221 cgtggaagaa tattctacta gttccgcatc ttcaagctgt tgttcctttc gtatagcttt
    11281 taaagcatct tcaggaaatc ccaattcatc gactaaacct acttcttttg cttggacacc
    11341 atcataaatc cttccatcag caattttttt gacttcttct tcagatttat tccgtccctc
    11401 gctgacgatt gctacaaaac gactatatgc gctgtcgata tatgcttgaa gcaccgcttc
    11461 ttcttctttt gtctctggtc gcgttcctga acccatatct ttcaacgctc cgcttttaac
    11521 tgttgtatct tccacaccca gtttttctag aagtcctgaa taattcaatc ctgacatgat
    11581 cacaccaatt gagccggtca ctgtttcttc tgttgcaaag attttatctg cttgagcaga
    11641 aatatagtag ccaccgctag ctgccatgtt tttcatgctg acatacattg ggatatcatg
    11701 ttctttacga atcgtatcca atttcttagc gatttccgca ctttcgtaga caccgccacc
    11761 aggagaattt acttctaaaa agataccttt gactgttgga tcttcttcaa tcgccttcag
    11821 ttgttccata aaatttttat gattgtaacc ttcagaagca aataaacctg aagaccctcc
    11881 cgcagcaatc gttccatcta ctgataattt tacgattttt tgcgtactgt ctccctcttc
    11941 caacacattt ggagctagtt cttcatcccc atataaccaa ctgttcaatc cctcaatttg
    12001 atcgttttcc tgaggcttag tcaaactagc tgaaactaac gaaaccacaa ataatcctgc
    12061 agcaatcaga actgctgccc aacgtctttt attcattctt tctcctttct aatacaagtt
    12121 ttttatgacg atcacagttt ctgactgctc agaagtgtcg aaccgctctg ctttttcttc
    12181 ccgcgcatac ccggaaaacg actcttttgt taattcatct tctaccgtaa actcacgagc
    12241 ttgagcaact tccaaggcat caggtgcgat ttcttggatg ctatcccagc cagtatctaa
    12301 aaatattttc gtatcatctg atacaccagc tgatgcttcg aatttggaca attgtttttt
    12361 taacattccc agtgtcatga tctcaatttt tgaatccatt tttactcctc ctctatccga
    12421 ttactttcta ttgtaccgaa ctcctgaaaa agatgataga taaaaaccca ttattttttg
    12481 acataaaaag gacatttgac aaagaatttg atatatacca atttattttt tattcttttt
    12541 ttgttgacaa gaacattcgc aaaaggttat gattttaaat gtttccagat aaaaaacaaa
    12601 aaggaggata gttatacctt ttaggatagc gccaggtctg tgtaaacaga tgacgaggag
    12661 agggtttatc gaaagattcg gcggatggcc ctagggactg cactctacag aaaatccaca
    12721 aaaaatgtct gcaaagataa aacaaaagga ttttcctgca gctggaagca ttcatacgaa
    12781 ttcattatag aaagtaggat gttttttatg tgcggaattg ttggaatgat tggattaaaa
    12841 aatgtaacac caggattgat tgacggtcta gaaaaattag aataccgtgg ttatgattca
    12901 gctggtatct ttgtctcaga tggcacaact gattatctgg tcaaagcaca aggcagaatt
    12961 caaaatttga aaaacaaaat aaatattgat actacaggaa atataggtat tggtcataca
    13021 cgatgggcaa ctcacgggca accttctgaa gaaaacgccc atccacatac ttcccaaagt
    13081 ggacgcttcg tgctcgttca caacggcgta atcgaaaact ttgaagaact taaaattgct
    13141 tatttagcaa atgaccactt tattggtgag accgatactg agattatcgc tcatctaatt
    13201 gaaactttcg cgaaggatac tacaacgcaa gaggcgtttt taaaagcttt gcgggtcatc
    13261 aaaggttctt acgctttcgc tttgattgat cggacagcac ctgatgttat ttacgtcgct
    13321 aaaaataaaa gtccactatt aatcggactc ggcgatggat tcaatgtgat tgccagcgat
    13381 gcaatggcta tgcttgctca tacgaaggaa ttcgttgaga ttgaagatga agagatggtt
    13441 accgtcacat cagaaaaagt tattattcaa aattttgcag gtgacatcgt agaacgttct
    13501 tcattcgaag cacaagtaga tgcttcagat atcgagaaag gtacctatcc tttttatatg
    13561 ctgaaagaaa tcgacgaaca gcctattatc atgcgtcgta tcgctcaaaa atacgtaaca
    13621 gaagacaatc gtgtctctct tgatcaaaag ctggtcgata cattgtctga tagcgatcga
    13681 atctatatcg ttgcttgcgg aactagttac catgcggggt tagcaggtaa acagactttg
    13741 gaaaaattga cacagattcc tgttgaggtt catttagcca gtgaatttgg ctataacaca
    13801 cctcttcttt caaaaaaacc attctttatt ttcttgagtc aaagtggcga aacagcagac
    13861 agccgccaag tgctggtaaa aatcaaccgt ctcggctacc cttcacttac gattacaaat
    13921 gttgctggtt ctactctttc gcgggaagca tcctttacac tgctattgca tgctggaccc
    13981 gaaatcgcag tagcatcaac gaaagcttat actgcacaaa tagctgtact aactttatta
    14041 gccaaagcta tcggtgataa aaaagaattt gaaacttctc ttgtattcga tatcactcat
    14101 gaattgagtt tagttgctaa tgcgatggaa tcggtcatcg cccaaaaaga ttatttagaa
    14161 gagttggcag aagtatatct cagcgataca agaaatgcct tttacattgg acgtggtgct
    14221 gactacaacg tttctcttga agctgctttg aaattgaaag aaatcagtta tatccaggca
    14281 gaaggttttg ccgctggcga attgaaacat ggaacgattg ctttgatcga agaaggaaca
    14341 ccagtgatcg gaatcatcag tgaagaagtg actggtgcgc atactcgagg aaacctgaaa
    14401 gaagtcgaaa gccgtggcgc taaaacacta gttattgtct cagagggatt agaaaaggaa
    14461 agtgaccagc tggtgctacc aactgtccac ccttatctaa ctactctaac cacagtcgta
    14521 ccgactcaat tacttgcata ttacgcaacg ctattacggg gattcgacgt tgacaaacca
    14581 cgtaatttag cgaaatcagt gacagtagaa taataaaaga acaaggacca gtgtcagaca
    14641 tctgacactg gtccttgttc ttttattttt tatgaaaata tctcttaatc cagtccgatt
    14701 tcttctttga ctactgccgc gattttatcg acatagtaat taactttctc atcagtaggc
    14761 gcttctgcca tcactcgaag taatggttct gtaccggaag gacgaactag gattcttcct
    14821 tctgatccca tttcagcttc tgcctcttca atcacttttt tgattgccgg aacatccatc
    14881 gcaccgtttt tatcacttac gcggatattc actaattttt gcggatagat tgttacctct
    14941 gctgcaagct ctgataattt cttacctgtc tgtttcatga tattcagtaa ctgaattcct
    15001 gaaagcatcc catctccagt tgtgttaaaa tctaagaaaa tcatgtgccc agactgctcg
    15061 ccgccaaagt tataatcgtt tttgcgcatt tcttctacaa cgtaacgatc accaacttgt
    15121 gtaacgacat ctttcaaacc gattccttcc accgctttgt ggaatcctaa gttactcatg
    15181 acagtcgtaa cgatcgtatc ttttttcaat cgattttttt ctgccaagta tttagcacag
    15241 ataaacatga ttttatcacc gtcgacaatg tttccaagtt catccaccgc aataatacga
    15301 tcgccatcgc catcgaaagc tagtccagca tctgctcctt tttcaacgac catctcagct
    15361 aaacgttctg gatgggtaga gcctacgccg tcattgatat ttaacccgtc tggatttgtg
    15421 cccattgtat aaaaatctgt ttcaagatcg gcaaacaaac gattaacact tgttgaagtt
    15481 gctccgtttg ctgcatcgac acaaatggtc aaaccggaaa ggtcaccgtt gatcgtttgt
    15541 acaaggaatt gagaatattt caataagcct tctggaaatt cttctacagt tcccaatcct
    15601 tcagctgatg gacgaggcaa ttcatccact tcagcatcta ataatgcttc aatttctagc
    15661 tcttggtcat ctactagttt aaaaccatct gcaccgaaaa atttgattcc attatcttgt
    15721 gctggattat gagaagcaga aatcatgacc cctgcgcttg ctttttgcaa acgtgtcaga
    15781 taagcaacac ctggtgtaga gatcacacct agctggaaca cttcgatacc caccgataaa
    15841 agtcctgaaa tcagcgcttc ttctaacatt tgacctgaga ttcttgtatc ccgccctact
    15901 aacacgcgtg ggcgttttcc ttcttcttca tgctggctta ggacataacc tccgcaccgt
    15961 cccagcttaa atgcaagttc tggcgtaagt tccttgttgg cttcaccgcg tacgccgtct
    16021 gttccaaaat atttacccat agttgtaaaa ttactccttt aacttaattt tctgaggaat
    16081 ttgttctgct catttgtgtt gattcgcttg tttctgatgt ttcttctgta cttgtggtcg
    16141 agctgcttgt cccagattcc gaactggaag aaatggttgt tgtcgatggt tccgttcctg
    16201 aatcagcaga tgaaatactt ctactcgtac ttgtattttc ttgtgtccga ctgctcgtcg
    16261 aagcagagct actgcttgac gtttgcaaca cgggtgtaat ctccacacta actgattcgg
    16321 gcttgatact taacccctct tctactggta tttcaatttt acgagttgtt cgatgattga
    16381 tacctgagac attgatcggt acagcaatac tgtcaccgat cgatgcaagc aaatcgctag
    16441 agccgcttac ttctgcttcc agttttgaaa aactgaaatc atagctttct accccggcag
    16501 ctggtgttcc ttgctgtatc ccataaagtc gtaccgactt gcttggcttg atcgaatcag
    16561 ctctcactgt tacttgcact ggatcagaga cgatacttaa tacttcccct gctgcattca
    16621 gcgcctgtat tgggacctca ctattaatcc catcatctgt gaccatcgaa gcgtccacat
    16681 cagctactac tcgtttgatt tctgccaatg ttttgtcacc tgtagtgata gagacttttt
    16741 taggactaac ggaagtatca tcaagttcat atccagatgg tgtgaacgtt gaaggaatca
    16801 acgtttccac atcgaaatct tttattacct ttttctcaac cgttactgta atagtcgatg
    16861 gttcgatctt tgctgtgaca gcactgctca aattttgaat ttttagcgga acttcatgtg
    16921 ttccttcgcc cagcttagtg atatctgctg tgacgcggaa catccgtgta tcttcgtttg
    16981 cctctgcatt caactgaact cggtttgcac tggaaagttt gacagtcact gcattttcat
    17041 atccatggat atagtagcgc tttgaatcat aagaaatctt gatcggcacc cccgtaactg
    17101 tttgattata cgcttcattt ccagaaagcg tatttggaac ggactggcca tttgcattga
    17161 agtacagcgc aatactgaac agcaatgcaa taaaactgta aagaatgctt gtccgtttct
    17221 cttttgagat catttgcgat cccctccctt agtcataccg tctaggaaag attgaatcac
    17281 gtttttcttg ttttttgttt tctcttcagc aattagttct ctacgcaaga ttgccaaata
    17341 ttcttgctgg gataagccag ccatcagttc attatctaac gtgatgctga cgtccccggt
    17401 ttcttcagag acaacgatgg taatcgcgtc actgacttcg cttataccga cagctgcccg
    17461 gtgtcgagtc ccgaattctt tagggatcaa catactttct gatagaggaa gataggcgct
    17521 tgctactgcg atctttcctt cttttacaat aactgcaccg tcatgcagcg gtgtattagg
    17581 aataaagata ttgatcagca gctccccagt gatatctgca tctaaagcaa tccctgtctc
    17641 aatatactca tctaatccag tatgacgttc gatagtgatc aacgcaccga tttttcgctt
    17701 ggacatatat tggatggctt tgtcaaaaga caagatcatc ttctcatctt cctgctgttc
    17761 gctttttgat tgtttgaaaa gcgaactgcg tccaagatgt tccagtcctc tccggatttc
    17821 cggctgaaaa atcacgatag cagctatcac cccgtacgta atgacttggt tcatcagcca
    17881 agacaaggtg tgcagaccaa tgatttccgc tacgattcgg ataacaataa aaatagctac
    17941 acctttcaga agctgaatcg cttttgtgcc tcgcagcagt tggatcagtt tgtatacaag
    18001 ataccagaca accagaatat caagtatgtt caccaaaaaa ttcagagaga acaagtcacc
    18061 ggaaaacatt tgctgccaat agtccaaatt aaaaagttcc ccgatttgaa atgacataaa
    18121 aagcctctct tctcttttga gatttcctct ctagtatatc atatgtttta attttagagg
    18181 ctgatatgct cgtatttttc ttgagaaaaa cgcataattt tcaagaaaat tgcaagtatg
    18241 cgttttattt ttctctgcaa taaatatttt taaacttcag agaattattc attatatttt
    18301 ttctgttatt tttccttttt ttcttttgta gcttgttcca tttttttacg tcgttctgct
    18361 ctggcagctc ttctagcagc tcttctttct tctgcttcaa ggtccgtcgt tttttctttt
    18421 ctagtcttaa cgggtacatc gatagattcc tctggttcaa gtcgtttctt gattttttct
    18481 aattctcccg tcagtgcagc atagttgtaa aaacgtgttt tagcgtcgtg gacagtcttt
    18541 tcaaataaag cttttgcaag atttggattt gcgttatcta gcgaggaaaa gcgaacttgt
    18601 ttcctcatga aatcaggcat agcagagaaa tcaggttttt tgtagtccaa agtcattggg
    18661 ttcttgtttt tttcgaccat tgtagggtta tatcgatata atgaccaata accagaagaa
    18721 acagcttctt ttgcttcttt aagcgattct ttcattccgc caagcaagcc atgtgtgata
    18781 caaggcgtat aggcaataat cagagaagga ccaggatact tttctgcttc ttcaaatgcc
    18841 ttgatcgttt gcatttgatt ggcacctgaa gcaatttgcg ccacataaac atttccatat
    18901 gtcatcgcca tcattcctag atctttcttt gaagcatact ttccactagc cgaaaattta
    18961 gcgattgccg aagctggtgt tgcttttgag gtttgaccgc cagtattgga atagacttcg
    19021 ttatccaaaa caaggatatt cacgtctgct ccgctggcaa gtacatgatc gatcccgcca
    19081 aaaccaatgt cgtaagccca tccgtctcca ccaatcatcc attggctgtt ttttacgaat
    19141 agatcctttc tcttgtatat atcctccagt tcagggaaaa ttgatcgttc gctttcgatc
    19201 gcagcttgca gttttgctgc tctttgctgc gttccttcac tctcaaacat gtgtactaac
    19261 cagtcttcca tcaattctcg tagttcttct gatacttttg gcaatacttc tttgattgaa
    19321 cttgccaaag cctcgcgacg agtctgtgcc gctagaagca taccataacc aaattcagca
    19381 ttatcttcca ataaagaatt tgaccatgca ggcccttgac cacattcatt ggtcgtataa
    19441 ggagaagcag gagaagcacc gccccaaata gaagaacagc ctgtcgcatt cgcgatcatc
    19501 attcgatcac cgaacatttg tgtcaataat tttacataag gtgtttcgcc acagcctgag
    19561 caagcgcccg agaattcaag aagcggttga ttgaattgtg tagacaagac agtattcttt
    19621 cctttgactg gatttgcttt ttgtcttaat gtcattgcaa aagcccaatt cacagcttgt
    19681 tctttctgtt cttcataagg cttcatcact aaagcttttt cttttgcggg acaagcctct
    19741 acacacagac cacaacctgt acagtcttcc actgaaactt ggatacggta ttttacgccg
    19801 tctgcgcctc gcatttctct cacgataaat ccttctggcg cttcttccat ttcctcttca
    19861 tctgctaaaa atggacggat ggcagcatga ggacaaacaa aggcacattc attacacatc
    19921 gtacagcgat cactaatcca ctcaggtact tctaaagcga cgccccgctt ttccatagaa
    19981 gccgttccta aaggcatttc gccagttgtc attccatttg ctacaagtgt accaacagag
    20041 agttgatttc cttcctgtgc attcactggt tcaagtattt cttgtatata accagtgttc
    20101 cttttattga ttttttcagg catctccaac gttctccaat ggtctgggat cgcgacttga
    20161 tgaagcagtt cggtcgtccg atcgattgct tgtatgtttt tttctacgat agccattgat
    20221 ttatgtccat agcttttcag ggcttcttct tttagcagcg gaagcacctc atcaaaagga
    20281 atgatgtcag ctaatttaaa aaaagccgtt tccattgccg tattgatccg gcgtcccaaa
    20341 ccgacttctt gggccaatct catggcattg atcgtataga atctaatgtt attttcagcc
    20401 aagtaacgtt ttaattttaa gggcagatgc gtttctaatt gttcgtcgct ccaaagagta
    20461 ttcaataaaa aaatgccacc tggcttcaat cctttgacca agtcatagct atgcaggtaa
    20521 gctggtgtgt gacaggcaac aaggtccgca tgctcgacaa gatacgctga acgtatcggc
    20581 gtatctccaa aacgaagatg agagacagtc agaccgccag attttttcga atcataataa
    20641 aaatagcctt gcgcatattt atcggtgtga tctccaataa tcttgatagc tgatttattt
    20701 gctccaactg ttccgtcaga tccaaatccc caaaacttgg cctggaatgt ttgcggttct
    20761 gtcaaatcca gactttcctt tggttccaaa gattgataag tcacatcatc cacgatccct
    20821 atggtaaacc gttttttgcg tatgcttggg tcttttttca attcatcaaa aactgctgag
    20881 atttggtcgg gagtcacatc tttagacccc aatccgtagc gaccaccaat aacagccggg
    20941 cgaagttcag aatcatataa cgcactttga acgtctaata agagaggttc tccacctgcc
    21001 cctggttctt tacttcgatc aagaacagca attgttttta ctgtatgagg caacttttgc
    21061 acgaatgttt ccactggaaa aggacgataa agatggatat tcaaaaaacc tgttttccgt
    21121 ccgtttgcat tcaagtaatc aatcgtttgt tcaatcgtct gtgcaactga tcccatagaa
    21181 acaatgactt cttccgcatc gtctgctccg taataagtca ccaagtcata agaagttcct
    21241 cgtaatcggt tgatctcttt catatatttt tgaacgattt caggtaattt atcataatag
    21301 gggttgatcg tttcccgttg ttgaaaatgg atgtctggat tctggttcgt accactaaca
    21361 gtcggatgat tgggattcat ccctcgttta cgaaatgaag ctaatttctc ctgattgatc
    21421 agaggagcta attcttcata ttccaaaact tcgatttttt gaatctcgtg actcgtacgg
    21481 aatccatcaa agaaattcaa aaaagggact tctccttcaa tagaagcaag atgggcaaca
    21541 ggtgctaaat ccatcacttc ttgtacactg ctttcagcta acatagcaaa tcctgtttgt
    21601 cttgcagcca tcacgtctcc gtgatctccg aaaatattca acgcatttgt cgtcactgcc
    21661 cgactagcaa cgtggaaaac acttggcagt agttccccag caatcttgta catattcggt
    21721 atcatcaaaa gcagcccttg tgaagcggta tatgtagttg tcagtgcacc agttttcaat
    21781 gatccatgga ccacaccagc tgctcctgct tcggattgca tttctactac ttttactggt
    21841 tgaccgaata cgttttcttt tcctgctgct gaccattgat ctactaattc agccatggtc
    21901 gaactgggtg ttattggata tattgcagca atctcggtaa atgcataaga aatatatgcg
    21961 gctgccgtat tgccatccat tgttttcatt tttcgcatga ttcatcatcc ttgttcatat
    22021 tctctcttat tatctgttcc attataacgt aaaacatgcc atttttttct tttatttata
    22081 aaaatatttt acatgtatct atttgaattg gtcatctaat ttttagacaa acagtctaaa
    22141 tcgttgcctt tttttgtcag acatgtataa actataagcg aaagaggtgt tttaacatgg
    22201 atatatcagt gattgatgca acgaaaacaa atacacaaaa aggaatcctt tatggttcat
    22261 cgaatgctcc taaaaaaatg gtcgaattca tcaacttagc ttgtccgtat tgccgacaat
    22321 ggtttgaaga atcttatgag ctattagaag aagcagtcca aagcgggcaa ttgcagcgag
    22381 tgatcaaatt gttcgataaa gaaaaagaaa gcttacagcg agggaacgtg atgcaccggt
    22441 atctcacaat cagcgatggc caaaaagcga tcaaagagat caaacaaata ttcgatactc
    22501 aagacgagtg gaaacatctt tctctccaag aagtagcgga ttttgcagta gataaactaa
    22561 agctgacaga acaaaaagac gaacagctga gccaagctgt catcaacgaa gctgagcaag
    22621 cacatattcg atttgttcca actgtcatct tgggtaaaga aatctttgat gaatctattt
    22681 caatagagga attaaaagaa ttgatccaaa caaaataaaa aaataaggag cgtgggacaa
    22741 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa gcagaagcaa
    22801 ctccttctta tttcttggag ttaaacgctt ctgtcccagc ctccttattc cgaataaatg
    22861 gtgtccaaaa gcttgcatct gccagattat ctcatttctt atgacaagct aagcaaatta
    22921 tctccaccaa ataatttatt catatttttg acttgcgcat actaactaat tcttaaattt
    22981 tcatacaaaa tttctcaatt tcccttaacg agtaatattt atgtacggtg attctcacta
    23041 gtatcccaat cactttttaa gttatcccga tttcaattct acttcaaaaa tagttgcttt
    23101 tatgtatgct gttagttgat tagatggtca tttgttgagc taggtcgttt attttaaaca
    23161 agttgtttct ttagcttata cctatctcgt ctaccaaacg caagatggca aacacaaatg
    23221 catacgcatc tgtatttgcc actttgattc gtataaagct aacaactatt aactcctctc
    23281 agctaatagt tgctctcttt tttattcaga ttcatttttg ctgatcacag cctagtattt
    23341 caatggtttt gaacactaaa ccaaattgtt ccattacaac attcactggc tgatgaaatg
    23401 gattagtaga tttcgattat tcaaagcgat tttctattgg tggatcgtgt tcccaactaa
    23461 taagacggat tccaaaccta tcgtacagat cttctaaacc acttataaat tttgcaccta
    23521 tttcaggtgt tttattgcgt ggatattcta ttgttacgcc attaaatgga taccaattag
    23581 gattaggctc tctttttttc tgtacatctc ccatagaata gttagcactt tctgggacat
    23641 aatatattct tcgaccatcc tctaattcat ctaataagat atttcgtgat cgtctatcac
    23701 ttgctaaatg tagacgccac gtgcgatacc atgccatgct acctgcatct gcagaaaatc
    23761 catcaaataa tgcaacaatt gtatcttcta tcacaatcct ttccccatct acttcatatt
    23821 ctaatctaaa atcaaactcc cctcgggtaa tttctggtct tggtggctta ggacccaata
    23881 ttattctact taaaaccgca ttcgttccca gatgaaacac agctataaca acaataatga
    23941 ttaatatttt gtttctattt gataaatttc tcattattcg cacatcacct ctacattctc
    24001 acatattagt tcgtaatact cctttaatat caaaatatct actggtcgta ataatattcg
    24061 ctatgaattc ctactactcg tataagaaag gccaaatcat cagcttttac ttgctgatga
    24121 tttggcttgt ttctatttat cgtaattgtt ttctaatcac caaaattgtt aacaatcggt
    24181 tcagatattt cccagttgat taaggtaatt ccgtattgtg tcaaaacttc ttgcgcttct
    24241 ccgaaattaa gtacagttct tatgtatcca ctttctccta atataaagtc tacctctctt
    24301 ttaaaacctt cctcgagatt tctaagggct atatgtggtt ttaatgacat tgattgtaca
    24361 ttttccccca tataatattg cgcacttcct cgactaaaat agattcctag atcgtcccca
    24421 aaaggtagat cttctctacc actagctaat ctacttctcc atcttcgttc tcttttcata
    24481 gaacctgcgc tgaactcaca cccgttaaac tcagctatga cagtatcttc aattatgtta
    24541 atctgtccat ctagttcgta ttcaatccta aatggaaatt ctccataggt gatttccggt
    24601 tcgggtattt taggtgagat taatgcaaag aaaggaaata ttaagcttgg caacatcaaa
    24661 aaaactcctc ctatgatcac aattcccgat gtaatccaaa atataatttg tacaattctc
    24721 attgatccat tgtattccat tttattcccc ctattactat tcatatccgc ctatctatat
    24781 cgatcttcca atgcagagat aattgcttcc ataccttgat tttttactga gttacctatg
    24841 cgagatatca ttctccacta aggtgcatca tattgtctat ctaacatgat taattctcca
    24901 ataggtgtat actcctccaa aaacaacatt taatgcatct ccctcgacaa cataagctac
    24961 catgtttgct gtatatgtgt ttgagtctaa ttcataagca gataaattta ctgtcgctgg
    25021 attaaatata atcgcattcg tatttatagc tactgaattt gctgcttcag caccaccttt
    25081 tgaatgtccg atcattgtga tttcaatagt aggatttacg tggacagccc tcaccgttta
    25141 ccctgaccat tatagaaatc gcttactttt ttgaactacg caacaaagga tacaatgctc
    25201 ctaacttcac tgtctccatt tttgtccact aaggaatata aaaaataggc attaattcat
    25261 ttaattcggt cacaacacgt tacct
//
LOCUS       DACCVH010000032        24744 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.032, whole genome shotgun sequence.
ACCESSION   DACCVH010000032 DACCVH010000000
VERSION     DACCVH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.032"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            9..731
                     /locus_tag="IVV98_001408"
     CDS             9..731
                     /locus_tag="IVV98_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP7807074.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            789..2828
                     /locus_tag="IVV98_001409"
     CDS             789..2828
                     /locus_tag="IVV98_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP7807075.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2937..4088)
                     /locus_tag="IVV98_001410"
     CDS             complement(2937..4088)
                     /locus_tag="IVV98_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7807076.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4242..4772)
                     /locus_tag="IVV98_001411"
     CDS             complement(4242..4772)
                     /locus_tag="IVV98_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807077.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4871..5221)
                     /locus_tag="IVV98_001412"
     CDS             complement(4871..5221)
                     /locus_tag="IVV98_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP7807078.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="IVV98_001413"
     CDS             complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="IVV98_001413"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP7807079.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="IVV98_001414"
     CDS             complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="IVV98_001414"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP7807080.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7624..8286)
                     /locus_tag="IVV98_001415"
     CDS             complement(7624..8286)
                     /locus_tag="IVV98_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807081.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8470..10116
                     /locus_tag="IVV98_001416"
     CDS             8470..10116
                     /locus_tag="IVV98_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP7807082.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10107..11189
                     /gene="uxuA"
                     /locus_tag="IVV98_001417"
     CDS             10107..11189
                     /gene="uxuA"
                     /locus_tag="IVV98_001417"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP7807083.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11297..12850)
                     /locus_tag="IVV98_001418"
     CDS             complement(11297..12850)
                     /locus_tag="IVV98_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7807084.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12998..14287
                     /locus_tag="IVV98_001419"
     CDS             12998..14287
                     /locus_tag="IVV98_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7807085.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(14413..15492)
                     /locus_tag="IVV98_001420"
     CDS             complement(14413..15492)
                     /locus_tag="IVV98_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7807086.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15601..16041)
                     /locus_tag="IVV98_001421"
     CDS             complement(15601..16041)
                     /locus_tag="IVV98_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7807087.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16098..16508)
                     /locus_tag="IVV98_001422"
     CDS             complement(16098..16508)
                     /locus_tag="IVV98_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP7807088.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16689..17123)
                     /locus_tag="IVV98_001423"
     CDS             complement(16689..17123)
                     /locus_tag="IVV98_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7807089.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(17223..18071)
                     /locus_tag="IVV98_001424"
     CDS             complement(17223..18071)
                     /locus_tag="IVV98_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7807090.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18460..20226
                     /locus_tag="IVV98_001425"
     CDS             18460..20226
                     /locus_tag="IVV98_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP7807091.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20328..21587
                     /locus_tag="IVV98_001426"
     CDS             20328..21587
                     /locus_tag="IVV98_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7807092.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21734..23035
                     /locus_tag="IVV98_001427"
     CDS             21734..23035
                     /locus_tag="IVV98_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807093.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23038..23889
                     /locus_tag="IVV98_001428"
     CDS             23038..23889
                     /locus_tag="IVV98_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807094.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23902..24717
                     /locus_tag="IVV98_001429"
     CDS             23902..24717
                     /locus_tag="IVV98_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP7807095.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
BASE COUNT         8352 a         4527 c         4600 g         7265 t
ORIGIN      
        1 tatctatttt gttactgctt acattagtag ttggctattt ttcgattgag tttatccatg
       61 gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt agagccgaaa agtatcccta
      121 ccacactaaa tgtggctttg attggttcag atgctcgttc gaaagacgaa aacggtcgct
      181 cggattcact tctggttgca caatacaacc agaaaacaca acaagcaaaa ctgatctcta
      241 tcatgagaga ttcatatgtc gatattccag gttacggaat gaataagata aatgcagctt
      301 actcttatgg gggagttgat ttattaaatc aaacattaaa ggaaaatttc aaatttgaag
      361 ctccctatta tgcaagtatc acatttcaag attttatcga ttgcgttaat gaactgtttc
      421 ctggtggagt caagatcgat gcagaaaaat ctctagattt agatggcgta tatataaaca
      481 aaggagagca agtgatggat ggtaatactt tactccagta tgctcgattt cgggaagaca
      541 aagaaggaga cttcgggagg atcagaaggc agcagcaagt gatcaaagct atctctcagc
      601 agctgaaaga cgtaacttca atattcaagc tacccaaagc ggttgggaaa ttacttggta
      661 gtatccaaac gaaccttcca gaaagtgtgc ttctggattg tggtatggat ttcctcaaag
      721 acatatgtta gaataaacag gtataaatag tgaaataaag gaatgacaag caagagaagg
      781 aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg aacaggcgct tatattgccg
      841 gcgcagtgat cttaatagca gctgcgggtg gcggttattt ttactaccag cactatcaag
      901 aaacccaagc agtagaagct ggagaaaaga cagttgagca atttgtccaa gctttgaaca
      961 agggagatta taacaaagct gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat
     1021 tatctgaaaa agagatctta gataaatacc agaatatata cggtgctgct gatgtcaaag
     1081 gacttcagat atcgaatcta aaagtagata aaaaagacga ttctacttac agtttttcat
     1141 ataaagcaaa gatgaatacc tcattaggtg aattgaaaga tctttcttat aaaggaacat
     1201 tagacagaaa tgatggtcaa accacgatca actggcaacc caacttggtt tttccagaaa
     1261 tggaaggaaa tgacaaagta agcctgacca cacaagaagc agcaagaggg aatattatag
     1321 atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa acaattagga gtcgttccaa
     1381 gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa agcgattgct tcctccttcg
     1441 acttaacaga agatgctatc aatcaggcga tttcacaaag ctgggtacaa cccgattact
     1501 ttgtcccatt gaaaatcatt gatggagcaa cgccagaact tccagctgga gctaccattc
     1561 aagaagtaga cggcagatat tatcctttgg gtgaagcagc tgctcagctg attggttacg
     1621 tgggagatat cacagcagaa gatattgata agaatccaga attaagcagt aatggaaaaa
     1681 tcggtcgctc aggtttggag atggcttttg ataaggatct tcgtgggaca acaggtggga
     1741 aattaagcat tacagatgca gacggtgtag agaaaaaagt tctgatcgaa catgaagttc
     1801 aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca
     1861 gtctaggagg aaaagctgga tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg
     1921 cgcttgctag ctctccaagc tatgatccaa acaaaatgac aaacgggatc tcacaagaag
     1981 attacaaagc ttatgaagaa aatcctgaac atccattcat cagccgattt gcgacaggtt
     2041 atgctcctgg atctacgttt aaaataatta cagcagcaat cggtctcgac aacggcacta
     2101 tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg gcaaaaagac agttcttggg
     2161 gatcttttca aacaacgcgt gtcagtagtg atgtatcaca agtagactta aaaactgctt
     2221 tgatctattc cgataatata tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat
     2281 ttcgtacagg cttagataaa ttcatttttg gtgaagacct tgatttgcca attagtatga
     2341 atccagcaca aatttctaat gaagatagct ttaactcaga tatcttgcta gctgatactg
     2401 gatatggaca gggcgaactt ctaattaatc ctatccagca agcagcaatg tattctgttt
     2461 ttaccaacaa tggcacactt gtctatccta aattgattgc agataaagag acaaaagata
     2521 agaagaatgt catcagcgaa acagcagtac aaacgatcgt gccagatctg agagaagttg
     2581 tgcaagatgt aaatggtaca gcacattctc tttctgcttt agggattccg ttggcagcga
     2641 aaactggtac agcggaaatc aaagaaaaac aggatgtaaa ggggcaagag aacagtttct
     2701 tgtttgcttt caatcttgat aaccaaggtt atatgatggt cagcatgttg gaaaataaag
     2761 aagatgatga ttcagcaacc aaacgagcat cggaactatt gcaatacctc aaccaaaatt
     2821 atcaataaaa aattgctttt taagtacagt aaaaggactg tggcgttatc gtcacagtcc
     2881 ttttttcaaa taaacggttt tcacgatgtc tctttcacaa cttctttttg atttactcac
     2941 acttcataaa ctttttttgt aaaatatttg agaacaagtg gagaaataag tgtacttaat
     3001 aaaatcacga taactaaagg tgaatagtac tgtggttcga tcaattgact ttgctgtcca
     3061 atttgtaaaa tgatcaaagc catttctcca cgcgaaatca taccagcacc gaccatcaat
     3121 gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat aacctccaag caatttggtc
     3181 aaaatcgcta caagcgtcaa tatagaaata aagagtagtt gttcactaaa gtcagaaaaa
     3241 tcaacttcta atcctacact gacaaaaaat actggtataa atactgcata tcctaaagcc
     3301 tctacattgt ggtatacttc ttctttaacc tttgtctgac tgacagctat cccagcaaaa
     3361 aaagcaccaa tgacagagct aagcccaaca agatccgcta cgtaagacat tcctaaacaa
     3421 ataactagcg atacgatgat aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt
     3481 aggaaaggcg caatccattt gactaataag aaaataaaaa caaaataaat tagctgttca
     3541 atcaaaacaa gcggtaaaga agcattgcta gaagcttccc ccgttagaaa agataggctg
     3601 aaacttagaa ctaaaacgac taaaatgtca tctaccacag aagcacccaa aattgttgat
     3661 ccttcttttg tattcactac gtttagttct tttaatactt ctactgaaat actgacagaa
     3721 gttgccgcaa gaataatccc aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg
     3781 cctgtcaacc agccaaaaac aaccgggaag atgatcccaa gcaaagcaac gaacatacca
     3841 ggtcggaaat attttttcaa aagagataaa tcactttcca gaccagctaa aaacattaat
     3901 aagatcacac caatctccga aaagtcatgg actagaatat caggtttgac ccaattcaat
     3961 ccagcttggc ctagcaaaac accaacaagt aattgtccaa tcactgctgg gatacctaat
     4021 ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata tcaggcataa aataccaata
     4081 aattccattc tcatcattcc tttgtataaa atatagcccg aacttagcat aacatacatt
     4141 attgaaaaaa taggaaaata tactcacaaa aaaaccaaca atccaaaaga tttttttgga
     4201 ttgttggttt ttatacggtc tattttaata actaaaaatg attaacgtat agtcattttt
     4261 cttattctga tgaaattgat aatctcctgg atgcccatga aaatcaaaat aaagccgaat
     4321 atttggaata gaagcatcaa acttttgaat ggattgaaca ataagacgaa tccgccaatc
     4381 aacaacagaa tactactata aacactccaa cttttagctt ttgtattcat gctgaagaac
     4441 aactggaaca agctgttgat gataacagct aatccaagaa gaatcggcag gatagaaacg
     4501 attgcaggtg caaaagcata gacgatcaga gctaagatca ggaaaaaaag accactgaac
     4561 agaccgatac tccaagaacc tgttttcctt ttaaaacggt aagcctcaaa aagattcaac
     4621 aacccaagca aaacaagata ggcggtgatc agataaccga taaaatgaaa aacagcagaa
     4681 gggtttagca caatcgcaat cccagaaata atataaacag cagctcttaa taaggcgtat
     4741 ttttgaatat tttgtttaat cgtctcaaac atataagaaa acctcctttg acttatttta
     4801 acgtgaacta gtcattttac caaattaaat gttacaaaat gagcgaagga gaagaatatc
     4861 tctggaaaaa tcaacttctg aggatctttt ccattttttt gccttttgct agctcatcga
     4921 tcattttatc taaataacga atttctttca tcaagttatc ctcgatgtct tctactcgta
     4981 caccacaaac aacacctgta atcaaggaac gtgaaggatt ggggacaggg gcttccgcaa
     5041 aaaattgttc gaaagtcact tgtttttgta gttgatattc tagttctgtt tgggaataac
     5101 ccgtcagcca acaaatgatt tcatctactt cctcttttat acgatctttt ctctccgctt
     5161 ttgctacata cataggataa acgcttgcaa aacttgtcgt aaaaatacga ttttgcgcca
     5221 taatcagtca cctttctttt tttcaaatta tttactactt atagtatata agaaaaagag
     5281 aagaaaaagc gattattcaa aaaaacaaaa aggattgtga caaaattctt gtcaccatcc
     5341 ttttttccgc tctctgactt tttacaatct tcatagctca agtgcgcatc agataatcga
     5401 atgctcctaa agctgcagta gctcctgaac ccattgaaac aatgatttgt ttgtatggac
     5461 tatctgtaca atcaccagct gcgaaaacgc cggggatatt cgttgcgcca tttttctcgg
     5521 tcactatttc atttcttgga ttcatttcga tcgttccatc tagccaatcc gtattaggga
     5581 gtaagccgac tagaatgaat actcctgaaa cagctagtgt atgcatctcc atcgtacggc
     5641 gatcgatata ggagagagat tctacctgat tcgtaccgct gatttctttc gtcgctgcat
     5701 gtttgataac agtgacattc gcaagagaga ctagtttatc ctgtaagatt tgatctgctt
     5761 ttaattctgg taagaattct agaacatata catgttttgc taacccagcc aaatcgattg
     5821 ctgcttcaac accagaatta ccaccaccga taacagcaat ctcttttcct ttaaataaag
     5881 ggccgtcaca gtgtgggcaa taagcaattc ctttattttt aaactctttt tcgcctggta
     5941 cattgataga acgccagtgc gcacctgtcg cgatgatggc ggtttttgct ttaagtgata
     6001 taccgttagc taagccaata ttaataaaat gttgctcttt atttaaggaa acggcctgtt
     6061 gattcatcat aatgtcgata gggtaactac gcacatgact ttctacttgc tgcatcaatt
     6121 ttggaccttc tgtgtaagag gtaccaatca tattttcaat ccctagtgtt tcaacgactt
     6181 gtccgccgaa agaatcagcg acaagtcctg tacggattcc tttacgtgct gcatagatag
     6241 ctgcactact agctgctggt ccaccgccaa ttactaatac atcataaggt tctttttcaa
     6301 acaactcttc ttcaatcaaa gggccagtga ttttttcaac aatttgttcg atcgtcatgc
     6361 gtccgctact aaattcttct ccatttaaaa acacagttgg cactgccatg atttttttat
     6421 catcgatttc tttttggaac atcccacctt caatcatcgt atgagtaata tttggattta
     6481 atacagctaa tatattcaat gcctgtacaa cgtcggggca attatgacaa gtcaagctaa
     6541 cataactgtc aaaatgcaat gtttgtgtta tttttttgat tttaagactc aaagattcac
     6601 tgattttcgg tgcccgtcca ctaatttgta acatagccag taaaaaagag gaaaattcat
     6661 gaccgagggg gataccagca aaaacgattc cactttcttt gccaactgga ttgatagaaa
     6721 aactaggtgt gcgcatcgaa tctctttttt cccaagagat tttaggagac atttctgcta
     6781 tttccttcgt aaattcagct agtttttgac tattttcact attatccaaa ctaacagaaa
     6841 aaacaatagg agattcaatc agtgctaaat attgttcgag attttgttta gtttctttgt
     6901 ctaacatatc caccacctaa atctttccaa caagatcaaa acttggtttc aatgtttcgc
     6961 cactttcttt ccattttgcc ggacaaactt cacctgggtg ggtacgtaca tattgagcag
     7021 cgcgaatctt atcaatcagt gcactagcgt cacgaccgat tccatctgca ttgatttcca
     7081 tagcttgaac gattccgtct ggatcaataa taaatgttcc tcgctgagct aatccttgct
     7141 cttcatccaa aacatcaaaa atacgagaaa tctgatgaga cggatcaccg atcatcacgt
     7201 attcgatttt accgatagca tctgatgtat catgccatgc tttgtgagta aagtgggtat
     7261 cggtagagca agaaaagact tcaacaccta aagatttcaa tgtactgtat tgttcttgta
     7321 agtcttctaa ttcagtagga caaacaaaag taaaatcagc tggatagaag caaagaatac
     7381 tccagttccc cataagatct ttttcactga cttctaaaaa ttctccttga tgataagcat
     7441 gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat agtaaaacct ccaataataa
     7501 ttatttattt ataattattg taatttagtt ggagttgcaa agtcaatgga tattttgtta
     7561 tttaataaag attactcaaa aacgaaggtt aattataaaa atagaagagg tcgcaagaaa
     7621 atgctactgc tggaaatact cgggataacg ttgagtaaca gtttcctgtt ctttcagcat
     7681 catgtgtaag tgcaatcccg tttgaaatcg agcttcttct ggttttttat caactaaagc
     7741 cttgagtaaa tcataatgtt gttccatgat cgtttcccat ggaagcccct gaatggtcac
     7801 tcgtaaccag cggaaacgtt ctaaatgggt attatggtca tctaaccagt tccaaacttc
     7861 ttttcttcct gcaatttcga aacaagcttc atgaaataaa ttatctgcac ggaaaaaagc
     7921 gcgttcgtca tttattttga ctgctttttc ttgttcttct aaaatcgttt ctagcactat
     7981 tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg atttgctctt ccaactgttc
     8041 tcggacaaag cgagcatttt ctgcagaaac aagattaatt ttggaaacat acgtaccact
     8101 ttgaggtatc gtatacacga gttcttgctg acgtagttga atcaatgctt cgcgaatggg
     8161 agtccggccg atagcaagat gttcctccag tgccttttca gatattttcc ttccaggttc
     8221 taagtcagca tagataattt gtttacgaat cgcttgataa gcttgtgatt gcaagctgct
     8281 tttcatcttt attcctccaa aatcatttct atgaacgtag tataacagaa gaggtctgaa
     8341 aaacaatctg gtatgtcaca ttaactagta aatttgtata aatagtaaaa ttttggttga
     8401 catagcgatt tttattgtat aaaattcact tgaatacaaa aactaatatg ttagtttagg
     8461 aggggaaaaa tgattgattt aaacaactgg aggaacttta tccctgaatt atctcaaaaa
     8521 gaagtagaaa tacctcattt tgaccgtgca tcattaagag aaaatggaca aaaaaatcct
     8581 gtctggatcc atttcggtgg cggaaatctt tatcgaggat ttcatgcaga aatcgctcaa
     8641 cgtttagcgg atctaggcga attgtccact ggtgtcattg tttgtgaaac attcgatgaa
     8701 gaaataattg aaagggctta ccaagatttt gatgatttga ttcttgaagt ggtcatgcca
     8761 agcagtggag agttcgtcaa acgtatatta gctgcgacag ctgacagtct gtattgtcat
     8821 ccagattgtt ctgaacactt tgataagatg attcgacact ttgaaaatcc tagtttacaa
     8881 ttagttactt ttgctattac tgaaaaaggt tatcgattga aagatacaaa taataaatat
     8941 ataggaccga ttgcagtcga tataaaaaat ggtccaaaga agccatcaca tacaatgagt
     9001 attcttgctg cgctacttta taaacgtttt ttatctggag cttggccgat tgcacttgtc
     9061 tctacagata atttttcaca aaacggtagt caattacgta cttctttgct aacgatcgca
     9121 aaagaatggc aaaaggaagg ttatgtacaa aatacattta tccaatactt atcgaatgaa
     9181 gaaattgttg cgtttccatg gacgatgatt gatcgtatca ccccgaatcc ttccttgtca
     9241 gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt cgattttcca aaccgcaaaa
     9301 ggaaataata ttgctccatt tgtcaataca gaggacatcc attatttaat catggaagat
     9361 cattttccca atggacgtcc gaaattcgaa aaagctgggg tattcttgac tgatcgtgca
     9421 acggtagata aagcagatac gatgaaggtg acgacttgcc ttaatccttt gcatacgtct
     9481 ttagctatta tgggttgttt actggggtat aggagcatag ctgaggagat gaaagatcca
     9541 gatttatcgc tgctagtttc tgaaatcggg tacaatgaag gcctcccagt tgtggagtct
     9601 ccaggtatca ttgatccaaa gatctttctg gaagaagtaa ttactgtgcg cttttctaat
     9661 ccaaatattc ctgatatgcc tcagcgaatc gccacggata cctctcaaaa ggtggcgatt
     9721 cgttatggtg agacgattaa aaaatatatg gaaatagaag ttaaagaccc gcagacactt
     9781 gtattcatac cattgactct cgctgcttgg cttcgatacc ttattggcat tgatgatcaa
     9841 ggaaaaccat tcatcccgag tccagaccca ctattgacag actttcagca taagctttcc
     9901 gatattcaac tgggtacgca agatacatca catattcatg agaaaatggc tcctattttg
     9961 tcaaataaag aaatttttgg tgtagatctt taccaagcag agcttggcag aaaaatagaa
    10021 gaaatgttca tcaagatggt agcaggaccg aatgccgtac gaaaaacatt acaggattac
    10081 ttacaagaac atggaggaaa tttatcatgg aaatgacttt tagatggtac ggatcacagg
    10141 aagaaaagat taccttagat gaaatcagac agattcctgc ggtcaaaggg attgtaggca
    10201 cattgatgga tataccagta ggagaggtat ggcccaggga gaggatcaaa gaactaaaag
    10261 aagaaattga gtctcgtggg ttaacactaa aagtaattga aagcgtcaat gtgcatgatg
    10321 ccattaaaat tggattacct tcccgtgagc agtatatcga aaactataag cagacaatcc
    10381 gaaacttggc agaatatgga atagaagtca tctgctataa ttttatgcct gtatttgact
    10441 gggtgaaatc tgaccttgac taccgcttag aagacggctc atccacgtta gcttttatat
    10501 ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg catcgaacat tccagcaatg
    10561 aatttgaatt gccgggatgg gaacctgagc gcttagctca tatcaaatcc ttgcttgaag
    10621 cctatgcatc agtagacgaa gaaaaacttc gagaaaattt tgcctatttt ctccaatcaa
    10681 tcatcccaac atgtgaagag gtaggggtca aaatggctgt acatccagat gatccgccat
    10741 actcgatttt tggattacct cgaatcgtaa agaatcgaga agatttagat tggttgtgcc
    10801 gcatagtaga cagcccttat aacggaatca ctctttgtac agggagtatt gcagaagatc
    10861 cagaaaatga tgtatatggg attttagcag aattttgtca aagagatcga atcccatttg
    10921 cacatgttcg aaatattaaa tttttagcta atcgagattt ctatgaggca ccgcataaat
    10981 ccgaatacgg ttcattagac atgtaccgca tactaaaaac aatgtatgac aacggattta
    11041 acgaatacat ccgtcctgat catggaagaa tgatctggaa tgagacagga agaccaggat
    11101 acggcttata tgatcgagca ttaggtgctg tttatctaaa tggattatgg gaagcaatcg
    11161 aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact gtaattttat tatgtaaata
    11221 agaaggatgt tcaaattctt gatacataaa tccggaggtt gttaataagc attcggattt
    11281 atgtatctta tttggtctag gaagtaactt gattttcttt tttcgattga tccatgagtg
    11341 cttcttcttt taattcaaag atatattctg agatcctcat aatcactttt ttccagtctt
    11401 ctggtgtgat gattcctttt aaaatataga tttttttgat atgagaaggc aattgtttca
    11461 aagggcagtc gctgataacg atgttgcagt tctccataaa atcattttgt attttgatcg
    11521 attcatttga aaaaatttgt tctatcttaa cgatcagatc tttactgata taaaaatcac
    11581 gcgtatagtt cacaccaatc acaattcgcg gctgtttttt gtagcgatca tacaaatgta
    11641 ctaggtcttc aaccatccat tgcacatttt ccttttctaa aataactggt aacaagtgtt
    11701 gattttgttc tctgaaatcc atataaaatt gttcaatggc ggtttggact tctttcaaca
    11761 cgctatgttc ttgataaagc atgaaagtag gaaggggcgt atttggttga ttgaagttaa
    11821 gaaatccatt ataaagttta tttcgtgcga atgccaatga gtaaagaatc ttttcttttt
    11881 caggtataaa caaatcaaat acagtacaaa aggactccac catttctctt gaataaagaa
    11941 catgaggaac gtttgctttt tttaaaagtt tgtattgctc caagcttgtt tcttccgatt
    12001 cgattttcgt gatagaaagt cgagctaaaa tattcactaa gatgcgttgt tcgcgacaaa
    12061 ttggcagatt aggtcgcaaa atatctacag agggatcaat aaaaaagtca atatattcat
    12121 actctgtgaa ttctttttgt acgtctttca cagaagttgc aggaaaattc tctttacata
    12181 tttttaatag aaaatataat ttatctatca taccgctatt tagtcggtca agtacttctt
    12241 ttttaaaaaa agtattcatc ataaaagcca ctacttgcgg atcttcatca taaaattctg
    12301 tagcagtact tgaaaagatg ttccaataaa tatctaatgc tgcatattga atttgtacct
    12361 cttttccaga aaaagacttt ctgccattat tagaaaagga gatagacaaa ccgtacaatg
    12421 ctaaaaatgc attaatcttt ttcattttcg tatacaaata agaggcacta tagtttgttt
    12481 gctgacttaa actgataatc gaatttgtct gacagctgaa caaagaagtc aagatctgat
    12541 aactgactga ttcgttgcag tatcttccaa atagacgata atagcagtaa gccggatcaa
    12601 ttccttcaaa attcaacttt aaaaaaggtt tttgcttatc aatatgcagt tctgttagat
    12661 tgagacgctc aaagtcttgt tctaattctt tgatgtatag taaaaaattt gattcagaca
    12721 tatggaaatg atctgctaaa tattgtgtag taataaagaa acgatgttca gataggaaaa
    12781 gaaaaatatc taattttgta ttgctttttt tcttcaagag aaacgtttta atcgcttctt
    12841 gagtttgcat gaaagaggct cctttttact taaattgtta aaacttgaaa atattactgt
    12901 ttttttcata aatttagaca aaaaaacagt aaacatatag gtagaatctc tactatctta
    12961 tttcttgcat acaaaaaaat caaggagtga gagagttatg agatattcaa ccatcttaat
    13021 atcaacattt gcagccttaa gcttatcgct tactataaat cagacagtcc acacagagga
    13081 gatagaaaca gccaaatgga cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca
    13141 ggatgaattt tcatccttca attcaggagt cgcaaaatta agaaaaggac aaacagcgac
    13201 catcaaagca aaaattgact attcaggaga cttagcacct atactacaat cagctgttac
    13261 atttgagaat gttgatcccg ctttgtcgat tggctatgac gagaacactt tgactatcca
    13321 acacaagcaa gcgatattta ccttcaccgt tacattaaat caggacttgt taaaaccagc
    13381 gctttttact gtcaaggtat cagatggact accgaacgat catcatcatt taacgccgta
    13441 tagtcagcgg cagacaattg agcaagattc agctatcgac tcaggaggag atcttgttga
    13501 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
    13561 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
    13621 agagccagac aatgaatcaa aacctgaaat aacccctgga gaaaaaccag atgtagaccc
    13681 agaagaaaaa ccggatgtga ctccagaacc agatacggat tctggaaacc aaacagtacc
    13741 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggcagcccc
    13801 agaagaaaaa ccagatgtaa ctccagaacc agatacggat tctggaaacc aaacagtacc
    13861 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaactag aggtagatcc
    13921 agaagaaaaa ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc
    13981 agaaaaaata aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa
    14041 tctagcaatt ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag
    14101 cgcccaatca gctgaaacct taaaaagtag caaggataca acctttgcta gtcctgaaac
    14161 gaaaaataaa cagctaccaa aatccggaga gtcacaaaac aaagttatac tgtggagcgg
    14221 aatcattcta ttaagtatag caacaatgct ttctgcaaaa agatttaaac aaaacagatc
    14281 tctctaacat ttgaataatg tctgtgaacg catttttcaa ataaaaagaa atatccagaa
    14341 aacgacccca aaataccaga ttgaaatctg atatttgggg tcgttcatac tttatctttc
    14401 ttcatattta ttttaaggga tatctgtttc ttttggaaga tggttcggga tctttttcac
    14461 tttcaataca tctaaaaaga aggtaaagat cggaatgccg acaatcaagc cccaaacgcc
    14521 aaagaaccgt tcgctaacaa gtaagaccac aaatgtataa aaaatcggca gttctgtttt
    14581 gctggacatc aacttcggat tcagcacata agactcaatt agatggacaa tcaaaatcgt
    14641 aatcaggata taaacaacat ctcggatgcc tccttgggaa taagctatga aagatagagg
    14701 aatacaagaa atgataacac ctgctactgg gatcagactt aaaatgaaaa tcatgatcgc
    14761 taaactcagc agctgatgaa agccaaatac agccaaggcg attgtagtga gcaacgtgtt
    14821 taaaagagcg ataacaaatt gagcttctaa taccaaacca aatgtattga caaacttatc
    14881 ggcaaaatag taaatatctt gaaagaacca agaaaattca ctttttaaaa acaatcttga
    14941 gaatacaatt gtttttttct tttcaatcat aaaaaagaaa cttaagatga atgacatagc
    15001 aaacgccact gccatttttc ctatatcctg taaatagcca agcgcaatcg aagcgccatt
    15061 ttgaagctgt tcaaaaaaat cgtttcgctc aatataagta tggatatatt gtaaaacagg
    15121 atctgcatct tttggctgat gctcgtaaaa atcaataacg gactggatca tatcaaatgt
    15181 ttgatgaata agcatcggga tatactttgt gaatgccaga tagataaggt aaacgatcag
    15241 tgtataaatc atgatagcta aaacacctgt agggattcgg acaaatcgct gaatgatttg
    15301 aacaagatga atcatcaaat aagtaaagat aaatgtgagc aaaatggttg taatcatact
    15361 tctaactaag aaaagaacaa aaacgacaaa taataaaaca gtgagacggc gtattttttc
    15421 attcgccaaa aaacgctgat aaacggtcaa atcgacaacc tccaaataac aaaaaataaa
    15481 cacgttattc attatatgat ggaatatgaa aataagaaag agaaagagca aaaagaaaaa
    15541 ccgctaaatg acgttatctt atgagttggt tttcctcata aaatcgttca tctagcagtt
    15601 tcagcccttt ttctggtctt gatgaaaatt atctagcatt tttcgggtca gatgttgcag
    15661 tgtatccaat tcttcctgtt caagtggaag ataagacttg atcttttgtg gaataccttc
    15721 tgcttgtttt tgcaacgcag caccttgagg agtcagcgta acatttacga ttctttcatc
    15781 acccgtttca cgctgacgat taatataatt tttttctgct aactttttta gtaagggagt
    15841 cagcgtacca gaatccagac acaaatcatt tcctagctct ttcactgaag tctttttctt
    15901 ttcccataaa actaacatca caagatactg ggtataggta agattcagcg gcttgaggag
    15961 ggaagtgtag tgtctaatga tttccttaga ggcggcatat aaaggaaaac atacttgatt
    16021 aactaaatat agatcttcca tttttccacc tccgctgttt tactatagtg tatcatagcg
    16081 gatttacaca aaaaagtcta ttcactaact gctttcagag taacttctat atttccagct
    16141 gtagcttttg aatacggaca cactttatgc gctgcctcta ataattcttg cgtttcttcc
    16201 agagaaagac cttcgataga tccttcaatc tctacaccta agacaaagct cgtttcactt
    16261 tctgaataaa gggaaacttg tgcactgaca gtagaagccc cagagatatt tttttgctgt
    16321 ttgatcaatt ctaatgcact gttaaaacat gcactgaaac cagctgcaaa caattgttca
    16381 gggttggttg cattttcgac gcgtttacca ggagctgcaa tattcaattc gaatgtacga
    16441 tcgggattat gaacttctcc agagcgtccg cctgtgttga tcattttcgt agaatacatt
    16501 tttttcataa aattaccacc tttaattata ttttatacaa ttgaatttta cacaatataa
    16561 ttgtggaaag caaagaaatg gattggcata agataaataa gagaaagcac atgaaacaga
    16621 cgcgctttct cgaatagcaa acatatacaa aaaaatatca gagacaaaaa ctaatctcat
    16681 cataaacatt acatatattt ctcaaaaagt tgttttcttt cttcaaaact tacttcacga
    16741 tggacctgat gaagcatcca taaataacca aaaggatctc tgaacattga gttagtcaca
    16801 ccaaagtcca tcatttctgt catttcttga atctctacac agccatttcg taatgcttta
    16861 ttatgtgtgt cctcgatatc agagacgatg atattgaacc agatcgtatt tggatgttca
    16921 gcagtaggag cagtcaaacc aagagacgtg ttttcatcca gcatatggaa tctcgtgcca
    16981 tacaaggtaa aaatgacttc attattgcct ctagggtaat ctgttgcctc aatcagttgt
    17041 atttcatcaa agattgtttg atacagttct agtgctttca aactatcatt taatacaaaa
    17101 tctatttccg ttcctttatg cataaagatc tcctctcctt ttcagtcgaa cagttactag
    17161 attcttttat tataccagtt aaagaaaacg cattcaaaaa aatagcggat ttacttacca
    17221 actcattcga ttggatgata agtaaatccg cgtcccatta cttctgctac gctgctgaca
    17281 atgacaaagg cacttggatc gatttcttct atcaatggtt tcattcggga aaattcatga
    17341 tcagtcacaa cgatcaataa aacctctttt gactttcgat tatacccgcc ttttgcctct
    17401 agcagggtaa ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc ttccaaataa
    17461 tgttcactca tgaccataac agatttcttt cgattgatac ctgtttcgat ataagtcatg
    17521 acaattgaag tgattgcaat agataaaata gcataaagaa actcttctat tccaaaaaca
    17581 aacagattaa gagaaacaac gaatgcgtct gtaaaaaata agccaatcga agtattcaag
    17641 tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga agagttgttt
    17701 ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac agacaacaac
    17761 cgatctgaag taatcattgt ttctggaact attgcaatga ttaaaggaaa aaacaagctt
    17821 ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata gaagagctag taccaacata
    17881 acgatattca acactaaaat aactatagct cggtcaaatc ctaaaacagc ttccagtaat
    17941 attcctagac cgctgacacc tccagcagca atatgatgag gccctaaaaa catattgata
    18001 gcgactccta atatgaagag ggcaaaaata atcttaatgt atgtccatat aaattgtctc
    18061 gtttctttca tttatccact tccttaattc attaataata ctcttatctt attataactt
    18121 acttttcacc ttaagttaac tttaattaat aaaaaaatta ggctagtcta aattattatg
    18181 tttcattctt ctagaatata cttctacgtt aaaaactgtt aaaaaacttt tactttagaa
    18241 aattggagaa attgatcgct taagataaat tcaggacact aaatagtaca ggaagtagat
    18301 taaaactttt aaaagtttta agtctatcta tttggcaagt ttaaaaaata aaaattcggt
    18361 atcaaaaaac tgttaccgat aacatttttg aaagcgttgt cttttgtttc tctatcactt
    18421 atagtgatga cgtcatatta aaacacaagg aggaaatcaa tggatacagc tgcaatttat
    18481 catcgaccgg aaagtgaata tgcatttcta tatacgaata caagatttcg tattcggctt
    18541 cgtactagga aaaatgatat caaaaaagta tatgtgcttt gtggagatcc atataccata
    18601 acaactgaaa aatggtatca aaaacaacga ccaatgaaaa aatgtctaag taccaatgtt
    18661 catgattatt gggaaattga agtgacgagc gaaacaaggc gcttacagta tgcgttccat
    18721 gttgttgggg aagataacac ggactgtttt tacggtgatc aaggaatttt tccttatcga
    18781 gaaaatgtga ttactgaacc aaatttttat tttcgaatac cttattttca tcaaatcgat
    18841 cgattcacta ttccagaatg ggtaaaagaa acagtatggt atcaaatttt tcccgaaaga
    18901 tttgcaaacg gggacaaagc aaatgacccc gaacacactt taccttgggg aagtaaagat
    18961 ccagaccgag aagacttctt cgggggagat ttgcaaggtg tgagggatca tttggattac
    19021 ttgacggacc ttggcgtcaa tggcatctat ttttgtccca tatttaaagc cacatccaat
    19081 cataaatacg atacgattga ttattatgag gtggatcccg cttttggcga taaaaaactt
    19141 ttaaaaaact tgattgatga agcacataaa agagggatac gtatcatgtt cgatgctgta
    19201 ttcaatcata tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa cggagaaaaa
    19261 tcgatctata aagactggtt ccacatccgt tttttcccag tagattctta tcagatgact
    19321 gacttaccag aaactgctga aaatatccca tatgatactt ttgcttttac tccattcatg
    19381 ccgaaactaa atacagcaaa tccagaagtg caaaaatatt tgctggatat cgcaacttat
    19441 tggataaaag aattcgatat tgatggatgg cgtcttgatg ttgctaatga agtcgatcat
    19501 catttttgga aaaaattcag agaagcagtt acagaaatca aaccagacat ctatatcctt
    19561 ggagagattt ggcattcctc tcaagcttgg ctgcaagggg atgaattcca tgcagtgatg
    19621 aattatgcat tcacagattc gattaaagat tattttgcaa aaaagaaaat cacagcttca
    19681 caaatggtca gtggaatgaa tcatcagcaa atgctttaca gagatcaggt gaacgaagga
    19741 acattcaact tattagattc tcatgatact gccaggatct tgaccctttg ccaaggtaac
    19801 aaagaattga tgaagtctgt gatggccttt atgtttcttc aaaaagggtc tccttgtatc
    19861 tattacggga cagaaatagg gatgactggt gaagatgacc cggattgccg caaatgtatg
    19921 atatgggaga aggaggaaca agatctagag ctattcggtt ttataaaaga acttgtttct
    19981 ctaaggaaac agttgtctaa gattatttct gaaggttcta ctcagtggct aatagtatat
    20041 gatcgtgaag ataagctcta tttcacacgg gaactagagg gacagatcat ctatgtttac
    20101 tttaatcagt caaaagaacc ttgggtagta gaacaggaaa atgaggtgat tcttagtcaa
    20161 aattgtcagt tgttagaaga cgggaaagca gagatacgac aatacggatt tttgatcatg
    20221 tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc aaatgaagat ttgtgcccat
    20281 tataataagg gtgtaacagc acgttgaata cacaggagga aatgaagatg aaaaaaagaa
    20341 gtgtgaaaca gttgggttta gggttaatct ctttaggaat cttaggcgga ttagcggctt
    20401 gtggcaatgg taactcttca gcagaagggg aagccgatga aggaaaaacg ttaacagttt
    20461 ccgttgattc tggatataaa gattatataa acgaaataaa aaacactttc gaaaaagaaa
    20521 acgatgtgaa aatcaagcta gtagaaaagg acatgttcga tcagttggaa tcattagcgt
    20581 tagatgggcc tgctggaaag ggacctgacg ttatgatggc agcatatgac cggatcggtg
    20641 cgttaggaca gcaaggacat ctggcggaag taaaactggg aaatgaagca gcttacgatg
    20701 aaacagacaa agcccaagtg acttatgatg gaaaaatcta cggagaacct gcagtaatcg
    20761 agacccttgt tttgtactat aacaaagatt tagtcgatac agcaccatca acgtttaaag
    20821 atttggagaa tctatccaaa gacagtcgtt ttgcttttga gtcagaagca ggaaaaaata
    20881 caggattttt agctaaatgg actgactttt attattccta tggtttaatt gcaggttacg
    20941 gtggctatgt atttggtgat gatggcacaa atccttcaga tatcggtttg aataatgcag
    21001 gtgctgtaga aggaatctct tatgcaacag attggttcaa aaatgtttgg ccaaagggaa
    21061 tgcaagacat aaaaagtgca ggagacttcg ccagccagca attcatgtcc aataaaactg
    21121 cagcaatcat tgacggtcca tggcaagcgc aaacatacaa agaaaacaat atcaattatg
    21181 gtgtagccaa aattcctact ctaaataatg gacagcctta tcaaccgttt ggcggaggaa
    21241 aaggatgggt agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa tggcttgatt
    21301 atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa atccctgcaa
    21361 accaacaagc tagggaaaca gcaaaggcta aaaacgatga attaacaaca gctgtgattg
    21421 aacaatatga aacagctcaa gcgatgccaa acatcccaga aatgggcgaa gtttggacag
    21481 gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa aacaccaaaa gaatccgcag
    21541 atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa atactgatta aaatgataac
    21601 cgtccatttt tataaaaaat ggaacaggtg cttcagataa aagtggcaag agcgagatgg
    21661 aaaattatct tgctcttgtt gccattatct taaaagcagt ttgcggttta gcaagtttag
    21721 agggggcatt cagatgcagc aagataaaac aagcaatatc aacgaaaaaa aaatcacgct
    21781 ttgttcactt attccaggga tggggcagtt tgtaaatggc caagctttta aaggtatcgt
    21841 ttttttcgcc atattcgtcc tattcattgg tcagatgctt ctgggcggat ttcatgcatt
    21901 ggtaggattg gttactttgg gaagtatacc aatggaagat cattcattat ttattttgat
    21961 tgaaggcact ttgcaattca tcattacaat cattttcttg attttttacg gtttgaatct
    22021 tttagacgct tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca atcggacgat
    22081 gaaggaagtc atacataata taggtgatga aggttttcct tatctattga cacttcccgc
    22141 ttatcttctc atgattttta cgatcatttt cccagtccta gttacattgt tcactgcatt
    22201 tactaattat gacttcaatc atattccacc agccagttta attgattggg taggggctaa
    22261 aaactttttt agtatcttct ttttaagctc atatcgtaat actttttttg cagtcttttc
    22321 gtggaccgtg atttggactt tatgtgcaac aactttgcaa atcacccttg gtattctcac
    22381 agcggttgtt gctcaccaga aatttattaa attcaaacgt attttcggta tcattttctt
    22441 attaccatgg gcggtcccag cttttattac tatcatgagt ttttcgaata tattcaacga
    22501 tagcgtaggt gccatcaata ctcaagtgat tcctttcata aaccagcttc cttttgtaga
    22561 tatcagtgca atctcttgga aaacggaccc gaactggacg aaagtagcaa ttatcttagt
    22621 gcagggctgg ttaggatttc cctatatcta tgtgatggtt acaggaatct tacaatcgat
    22681 ttcagaagac ttatatgaag cagcaaaaat cgacggagca aatgcatggc agcgcttttc
    22741 aaacatcacg cttcctgctg tcttcctagt ggcagcgcca acatttatta cacagtatac
    22801 ggggaatttc aataatttct ccatgatcta tctgtttaac aatggtggtc ccggaagcgt
    22861 aggcggagga gctggttcta ctgatattct tatttcctgg atctataaac ttacgactgg
    22921 aacttctccg cagtattcta tggcttcagc aatcacgttg attatctccg tcatcgttat
    22981 ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc aatatggggg attaacaatg
    23041 aaaaaatttc attcgagtgc tcgattccaa aaacgacttt ctcacttttt tacttacttt
    23101 tttcttttaa tactgtcagt cattatcatc tatccgcttt tgatcacagc aagtactgcc
    23161 ttcaagtcag gaaatattgc agcttttagt ttagatcttt caagtgactg gactttagga
    23221 aactttactc ggctattcag tgaaacactt tacgggactt ggtataaaaa tacattgatc
    23281 atttctgtcc taacaatgat cgtacaagtg actgtagtaa ctttggcggg ctatacttat
    23341 agtcgctatc gttttatcgg ccgcaaatca agtttgatgt tctttttagt gattcagatg
    23401 gtaccgacta tggcagcatt gactgccttt tatgtcatgg ctttcttatt agaagcgctc
    23461 gataagtact ggttcttgac aatgatctat ataggcggtg gaattccaat gaatacttgg
    23521 ctgatgaaag gatactttga cactgtacca atagatttag atgaatctgc taaacttgat
    23581 ggggcagggc atttcaggat ttttttccag attgtattac cgcttgtcaa accgatgctc
    23641 gccgttcaag cattatgggc ttttatggga ccttttgggg atttcatgtt agctaagttc
    23701 ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct tacaaacatt tatttctgat
    23761 gtgacaaacc aaagagtctc tctttttgct gctggggcaa ttttgattgc actaccgatt
    23821 tgtctattat tcttcttttt acaaaagaac tttgttaccg gcctgacatc tggcggaaca
    23881 aaaggatagg agcagagtat catgcaaaca tttccgttaa actatttttc cgcattacgt
    23941 acgccaactc aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt tttcttgata
    24001 tttgtatttt tagtttcctt gatggtcatg cctgtgactc ttttttatgc caatcagatc
    24061 caagcgattc cattagaaca atttctatcc gttcattcgc tgatcgatga acaaggaacc
    24121 caaaaatttt ctgaacttga attatctgaa actgggttac aagcatcgca acaaacgata
    24181 gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca atccgatcat
    24241 ggaactttta ttgattttga gaaggaacaa tgggtgatcc aacaaaagga taaatctggt
    24301 atacgccgct atacgatgaa ttatagccca tctttccaac cagattctgt acgtacgccc
    24361 gaagatttcc aacgattttt agaaagagaa ttttatgcca gtaatcgtcc aacaatcatt
    24421 ttatcttata gtttaagtct tggtcttgtc ctatttgtca tgacgagtct cattttattc
    24481 ggggcttcct ttttcttgtg gatgacaaga aaaagccaac tttcatccat tcatacattc
    24541 aaagagagtg caaatttgat gctgaatgtt atgggaatag gttccatggc agcagcagtt
    24601 gtagggttta tccactttga ctttatcttg atgctaagtg tccaaacaac gataactgtc
    24661 ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt cgaatgacaa
    24721 gtttaagcga tttatgcgac aatg
//
LOCUS       DACCVH010000033        24440 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.033, whole genome shotgun sequence.
ACCESSION   DACCVH010000033 DACCVH010000000
VERSION     DACCVH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.033"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(33..881)
                     /locus_tag="IVV98_001430"
     CDS             complement(33..881)
                     /locus_tag="IVV98_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7807096.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1105..3045)
                     /gene="thrS"
                     /locus_tag="IVV98_001431"
     CDS             complement(1105..3045)
                     /gene="thrS"
                     /locus_tag="IVV98_001431"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP7807097.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3382..3561)
                     /locus_tag="IVV98_001432"
     CDS             complement(3382..3561)
                     /locus_tag="IVV98_001432"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP7807098.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3608..5431)
                     /gene="cadA"
                     /locus_tag="IVV98_001433"
     CDS             complement(3608..5431)
                     /gene="cadA"
                     /locus_tag="IVV98_001433"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP7807099.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5709..7988
                     /locus_tag="IVV98_001434"
     CDS             5709..7988
                     /locus_tag="IVV98_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7807100.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8081..8728)
                     /locus_tag="IVV98_001435"
     CDS             complement(8081..8728)
                     /locus_tag="IVV98_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807101.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8907..9626)
                     /locus_tag="IVV98_001436"
     CDS             complement(8907..9626)
                     /locus_tag="IVV98_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7807102.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9757..10908)
                     /locus_tag="IVV98_001437"
     CDS             complement(9757..10908)
                     /locus_tag="IVV98_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP7807103.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11125..11865)
                     /locus_tag="IVV98_001438"
     CDS             complement(11125..11865)
                     /locus_tag="IVV98_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7807104.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11869..12192)
                     /gene="rsfS"
                     /locus_tag="IVV98_001439"
     CDS             complement(11869..12192)
                     /gene="rsfS"
                     /locus_tag="IVV98_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP7807105.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12249..12842)
                     /locus_tag="IVV98_001440"
     CDS             complement(12249..12842)
                     /locus_tag="IVV98_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7807106.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12826..13473)
                     /locus_tag="IVV98_001441"
     CDS             complement(12826..13473)
                     /locus_tag="IVV98_001441"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP7807107.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13486..13797)
                     /gene="yhbY"
                     /locus_tag="IVV98_001442"
     CDS             complement(13486..13797)
                     /gene="yhbY"
                     /locus_tag="IVV98_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP7807108.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13813..14922)
                     /gene="yqeH"
                     /locus_tag="IVV98_001443"
     CDS             complement(13813..14922)
                     /gene="yqeH"
                     /locus_tag="IVV98_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP7807109.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14919..15446)
                     /locus_tag="IVV98_001444"
     CDS             complement(14919..15446)
                     /locus_tag="IVV98_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP7807110.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15626..16411)
                     /locus_tag="IVV98_001445"
     CDS             complement(15626..16411)
                     /locus_tag="IVV98_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP7807111.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16404..17273)
                     /locus_tag="IVV98_001446"
     CDS             complement(16404..17273)
                     /locus_tag="IVV98_001446"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP7807112.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17274..18653)
                     /locus_tag="IVV98_001447"
     CDS             complement(17274..18653)
                     /locus_tag="IVV98_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP7807113.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18661..19080)
                     /gene="fabZ"
                     /locus_tag="IVV98_001448"
     CDS             complement(18661..19080)
                     /gene="fabZ"
                     /locus_tag="IVV98_001448"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP7807114.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19105..19581)
                     /gene="accB"
                     /locus_tag="IVV98_001449"
     CDS             complement(19105..19581)
                     /gene="accB"
                     /locus_tag="IVV98_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP7807115.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19584..20819)
                     /gene="fabF"
                     /locus_tag="IVV98_001450"
     CDS             complement(19584..20819)
                     /gene="fabF"
                     /locus_tag="IVV98_001450"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP7807116.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20838..21575)
                     /gene="fabG"
                     /locus_tag="IVV98_001451"
     CDS             complement(20838..21575)
                     /gene="fabG"
                     /locus_tag="IVV98_001451"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP7807117.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21587..22504)
                     /gene="fabD"
                     /locus_tag="IVV98_001452"
     CDS             complement(21587..22504)
                     /gene="fabD"
                     /locus_tag="IVV98_001452"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP7807118.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22611..22835)
                     /locus_tag="IVV98_001453"
     CDS             complement(22611..22835)
                     /locus_tag="IVV98_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP7807119.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22888..23850)
                     /locus_tag="IVV98_001454"
     CDS             complement(22888..23850)
                     /locus_tag="IVV98_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP7807120.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23860..24300)
                     /locus_tag="IVV98_001455"
     CDS             complement(23860..24300)
                     /locus_tag="IVV98_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7807121.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6693 a         5438 c         4250 g         8059 t
ORIGIN      
        1 ctaaaaaact tatataaaaa atagtaaggt ttttatttcg aatccataaa atattcttgg
       61 attgcttctc gtgttttttt cactttttcg ctaagctttt cgtttttagc catatagaaa
      121 taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg aattagttgc cgcacttcga
      181 ttcgtgattt cttttggtct agatgtttgt acgagtacat cggctatctt gctaagcggg
      241 ttatttccaa attgcgtcaa cgcaatgatt tcgatattca tgcttttcgc cagctcggct
      301 aatgcgacta catctgcact tctacctgag tttgaaacaa gccaaagcac tttctttttc
      361 tcattgctga caagttgcgg gagcaagacg tggatatctt tttcaaaaat gattggctta
      421 ccgacacgag accatttttg cagaatatct tctactacta aagaagaggc gccaacccca
      481 tataaaaaaa cagtctctgc cgattccaaa cactctacga ctttttggat cgtttcttct
      541 tctagaatat ctactgtttc ttttatcgct acttgtgcat tgttaccaag tttgtttttg
      601 atagagtaaa aggactcatt tgcttctata tcactaaaac cttcatcgat tccagtctgt
      661 agttctgttg aaatcgtgat tttgaagtcc gtcagacttt gaaaaccgat ttttttggaa
      721 aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg ctaattcatt agctgtcatt
      781 gtagggacct tctcaatatt accgataatg tagttggcca actttttttc tgctgaagaa
      841 taatcttcca tcatactttc aatacgacta attacgctca taagttcctc caccctttta
      901 atgatagtct atgtaagtat accatatcag acccttattc acggtcgtat actggataaa
      961 aaacaaaaaa acaatccgcc caacagaata tcttatccca tcaatcccac agattctatt
     1021 gagcatctgt gtctttgagg aatacctgtt atctattgtt cggattgctt tctatctact
     1081 acttttttac aggaaattta cctattagtt ttctctgctg taatttttga cttctgcttc
     1141 catagcatca ataaagatat tcaaatcttc tacagctgtt tctttacttc cataacgacg
     1201 tacgttcact gttgcatctt ccaattcctt gtctccaaca actaattggt aagggatctt
     1261 ttgtgtttga gaggcacgta tcttatagcc cattttttca ttacgatcat caacttctac
     1321 acgcaacccc ttcatttgca aacgttcttt gatttcataa gcataatcgc catgtgcatc
     1381 aacagaaaca gggatgattg ttgcttgtat aggtgccaac catgttggaa aagcgccttt
     1441 gtatacttct gttaaataag cgacaaaacg ttccattgta gaaacaattc cgcggtggat
     1501 aactactgga cgatgcgtat tttccccgtc ttctccaaca tatgtcaaat caaagcgctc
     1561 tggcaataag aagtctaatt gtatagttga taatgtttct tctgtaccaa gagctgtttt
     1621 gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg ccttctgctt caaagtaatc
     1681 tagttctaat tcatccatag cggctttcag cattgcttgg gctttttccc acattgcgtc
     1741 atcatcaaaa tatttatctg tattgtttgg atcgcgatag ctcaagcgga aacgataatc
     1801 tgtaatattg aagtcagcat atactgccac catcaattca agcgtacgtt taaattcatc
     1861 tttgatttga tcaggacgaa caaatgtatg accatcattc aacgtcattt ctcgtacacg
     1921 ttgtaaacct gacaaagcac ctgatttttc atagcgatgc atcattccta attcagcgat
     1981 acgaattggt aattcacgat aagaatggat cgtgtttttg tagaccatca tgtgatgagg
     2041 gcagttcatt gggcgaagaa caagcatttc gccatctccc atatccattg gcgggaacat
     2101 gtcttcttga taatgatccc agtgtccaga tgttttgtac aactcaacat ctcccattat
     2161 tggtgtatat acatgttggt aacctagact aacttctttg tctacgatat aacgttcgat
     2221 cgtgcgtcgg attgttgccc cttttggaag ccagaatggc aaaccagaac ctacttctgg
     2281 ggaaaccatg aacaagtcaa gttcttttcc tagtttacga tggtctcttt cttttgcttc
     2341 ttcacggaga cggatatatt ctttcaaagc tttcttgtca aaaaaggctg tcccgtatac
     2401 acgttgcatc atttgattgt ttgagtttcc acgccaataa gcacctgcca ctgataataa
     2461 tttaaatact tgtatacggc cagtggatgg aacatgtggt ccacgacaca aatcgatgaa
     2521 ttcgccttgt tgataagcag taatcacttc ttcttctggc aattcactaa tcagttctac
     2581 tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt tttgaaagaa cacggcgttc
     2641 gatcggcaga ttttctttga cgattttcat catttctgct tcgattgccg gcaaatcttc
     2701 tgcagttact tggttttgtc cattatctgt atcgtagtaa aaccctgaat cgatagctgg
     2761 tccaacgcca aagtggatat ttggatagag gcgacgcatg gcttgggcca tcaaatgagc
     2821 tgctgaatga cggactaagc caagtgcatc ttcatggtct ggtgtgatga tctcaatact
     2881 tgcatcttcc tcgattggac gagtcaaatc aacgagtttt ccgttcactt taccagctaa
     2941 agcttttttt gctaagcttt ttgaaatgct ttcagcaatt gccaatgttg ttgttccaga
     3001 ctcaaattct ttgactgcac catctggaaa agtaattttt atcataatag tttcctcctt
     3061 gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa aaaaatccta gcatctcttg
     3121 aaaagagata ctaggacgaa aagttcgtgg ttccacctaa tgttcaaacg caaatgcgtt
     3181 cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca agggtttcga aagtggtcat
     3241 cctttggttt tctcctggaa aagtttcagc ctagcttttc ctctcttatc gaagactctc
     3301 aaattcagtt ggctttctca tcaatcaatt atgtgtttat ttaaccacta ataaatagaa
     3361 aaatcaagtg ggaaactaaa cttatttttt ccattcccca tttacaccgt atgttccttt
     3421 tttcatctca ttgatgatga catggatgtg ttcttttggt gcctgcgtgt ttttatgaac
     3481 agcttccgtg atatctttca tcatattttc taattgttcc ggactgcgac cttctactaa
     3541 ttcgacatgt acgaatggca taatgctctc tcctctttct gatcgttctt ttttcaactc
     3601 gattctatca tactatgttt gtcttgggta ctgaatcagg aaaaatggct ggatcttttt
     3661 ttgctctcaa ggcactcaaa atagagaccg tatccacgac ttcttgcaaa acagctccga
     3721 ataatgcggg gattagtccc gtacttgcaa ttaacatcaa aaaaatacaa ataaagatgc
     3781 caatcagtac agactgtttc gctattctca tcgtatctct tgaaatcact actgcttttg
     3841 ctacacgcaa gagatcatct ttcaagatga ccgcatctgc actttcacta gcagctgtag
     3901 aaccatgagc ccccattgca ataccgatat ctgcagcagc aagtgctggt gcgtcattca
     3961 cgccgtctcc taccatcgca acaggtcttt gatctttagg gatactttct aaaatggtca
     4021 gtttatcttg aggcaagcta cgggcatgta cagaatctaa ttggactttt tctgcaatcg
     4081 tttgagcaat ggcagatcca tccccggtga tcatcatcaa atttttcaca tcaagttttc
     4141 ttagctcctt gattgtcttt gctgcttctg ggcgaatctg atccgaaaat aggatcgttc
     4201 ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt ggacgtttct atttcttcag
     4261 ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt attgactact gcttggattc
     4321 cttgaccggt cacttctttc agttgactaa caggatacag ttggctgttt ttcacgttgt
     4381 tcactaacga acgagctaag atatggctag attcctgttc tgcactagct gcatacagaa
     4441 gtagctcttc tttttttatt ccattgactg gctgaatcgc ctctacttcc aatatccctt
     4501 tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt acgtgcgagc ttttcaatcg
     4561 ttgttccagt ttttacaacg atcccgtttt tacttgaacg gctcattcct gcaactaaag
     4621 caatgggcgc agctagaatc agtggacaag gtgatgccac taccagtacc tcagcaaatc
     4681 gtaaagggtc ttttgagaac caccaagaaa taccaccgat caaataagca atcaacgtga
     4741 aagggactgc ataacgatca gctaaacgga caaatcgggc aggcttttct tttgattctt
     4801 cgactagttt aataatcatt tgatactggc tgtctgcggc acgtttttca gcgatcattt
     4861 ggatcgatcc gtctccattt aaagaccctg acataatctg atctccaggt ttcttggttt
     4921 ccgggcggga ctcacctgtc aaagaagatt catcgaccga agattctcct ttggtcactc
     4981 gaccatctgc gggtacaagt tcgccaggct tgactagtaa ctggtcatca atatttattt
     5041 catcgattac tatatcctgc aattttcctt ctttgaatcg atgggcaatt cttggggtgt
     5101 tatctaacaa agactgcagt tctttacccg ctcgtttatt cgcgtaatcc tctagactat
     5161 ctccgcccgt aagcatgatc aatatcatca aactagccca gtattctttg acggctaatg
     5221 ttgcaaggat tgcggtaatc gctaatacat ctacgccata tcttcctgaa cgtaacgtct
     5281 tgatcatttc caaaaacatc aagaaggcga gaatccctcc agtaaatgcg acaatcgcaa
     5341 atgcaagggc cggctggtga aaaacaaatt cacttaataa agctatccca ccaataagca
     5401 aagtaagtaa aaattttttg aaatgtgtca ttgttttttc tcctctttta tgtgacttag
     5461 agaggttagt aataaatttc cagctgcctc tttcatctta agcatagtcc ttgactagca
     5521 ctttttaaaa caataggcct taattgaaaa caactatcac tatcagcgtt tccaaaattc
     5581 atcagttcta caaacaaaaa tattcagcaa ggattacttt ttcgattcat cagttaaaaa
     5641 gtaccttttt tcgaaaaact atgctatact tttaattcgt tatttacggc ggaaggagca
     5701 aacatgcgat gaatgagaaa caactagaac aaacgcacgt ggatgaaacg atcgaactaa
     5761 tccagatcga acaaaatatg ctggatacaa aacaacaaga attgactcag gaaatgaatc
     5821 attcgacaaa agacacagct aatcacaaga ttcgagctgg ttccaatgaa gctttttatg
     5881 aatctgctgt tgaatatcgc caacatgagc aggaattgct tttgaaatac catactcttg
     5941 aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa agatagtcct tattttgccc
     6001 gtatcgactt taaagaagac cgtgaaacag aaacattata tctaggtatc gcttctttaa
     6061 gagatctggc agaagaaaca atcgttattg actggcgcgc accaattgcc aatctttatt
     6121 atgaaggtga gattggtccc gcattttatg aaactgaaac agatagaata gatgtcgatc
     6181 tgcagttgaa acgacaattt aaaatccaag aaggacgtat tttatctatg gtagatacgt
     6241 cggaagtaat caatgatgac tttttgctag agatattgga tgaatcatca agcaaccata
     6301 tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc aatcattcgg gacacaacaa
     6361 gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa gacatccgct ttgcttcaac
     6421 gtattgcttt tctgttgtat cataatcgca agtggctcga ggctgaaaac gttcttctat
     6481 tttcacccaa ccatttgttt tctgattaca tctcgactgt attgccttca ttaggtgaaa
     6541 gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca gctgctgcca gagttttctt
     6601 tactagatga acagcaacaa gaaagtggtt ttttgctagg ggaaaaagat ccgatacaag
     6661 tgatgaaaag cggattgacc ttagtcgatc agattgatcg ctatatccaa ggcatcacaa
     6721 actacggtcc cttgttccgt gatatgaaaa taaatggccg tacgatccta tcaaaggaat
     6781 cgattcgcca atggtataaa gaaacaaatg aacaattacc tttacatcat agactttctc
     6841 tattacaaac gaagctcctg aaaaaattag gcggtctgca aaaagacgaa acacgtcagc
     6901 aatgggtcaa agatctggcg gaagaacagc tccaagaact atacgcaaca gatccaaatc
     6961 ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa actggccaac caaatcgtac
     7021 gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta tcaatttgtc aatataacga
     7081 aacaatatct ccactttcta caaactgtgc cactttctct tctaacacga cataaaatca
     7141 gcgagaccag gtggcaggaa catttgacaa ctgttcgtac acacttgcgt caaagagaat
     7201 tgcgtcaaga ggatgctgta ctattctttt tactgatgcg ccgaacatat ccagtgacgg
     7261 ttacacacaa agctcgctat atctttattg atgaaatgca ggatttcgca ccatcacaag
     7321 tggcattgct gcaagccttg ttcccaaaag caaatttgac tttctgtgga gatctaaatc
     7381 aaaatgtctt tggaaatgaa acgatcgttg gatcattgga agaccttttc gtggaccgtg
     7441 aagtcactcg tttccaatta acgacaagct atcgctccac aaaagaaatc actgattttg
     7501 ctaatcattt tattgtgaaa gaacatcaag tagaaacaac agcaagaaaa ggagaccttc
     7561 ctttgctcat ccaaggaaca acagatgata tcaaattgaa ttggttagca gataccattc
     7621 gaacgactca gggaaaagcc cggtattggc gtacagcaat catagctaaa acacaagaag
     7681 aatgcgaagc tctttatgct caactgccag acgagttgaa acaacaagtc cagctgattt
     7741 taaatgagag tgactttatg aagcgttcca ttattttact tccagccttt ttagcaaaag
     7801 gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc agaacatttt tcttctcagc
     7861 aagacaaatt gatcctttac accatgtgta cacgtgcgat gcatgaattg acccttttta
     7921 cctccaataa tgaaagtcct ttgttaaaca atatggatat ttcatcttat gagaaaaaag
     7981 tactgtaagt aaaaagacaa ctgctatcat taatgttagc agttgtcttt ttatttacaa
     8041 taataattgc agaaaaagta attcaatcat ttaaggtcat ttattctata tataaatcca
     8101 aatctgtttc aggatatttt aatttgacaa gcgaaataat cattttcagt tcttccatgt
     8161 tttctggata ttctgggtca aataccttgc tatgacggcc aatcccgcca ttgtcgatca
     8221 atcggtaaat tcgattccat tcaatgaatt ggtcaattga ttggaaattg ctgattggat
     8281 agccgccaca atccaaaatc tctgatacac gaaatgctag gtatgcacta tcgatcactt
     8341 tatttttttt cgtgtctatc ttctcatttc tttcgataag aattttttca ggacgatgtt
     8401 tcaagctcca ctctaatagt agaaagaaag cctccatccg atactcttct tcaaataacc
     8461 gaaaggctga atcagaacga cgaaaaagca gcggaatcag ataattttgt ctataaatca
     8521 gcattggtgc gcggtccacc atacactcta aataacggtt cagataccct gtaccgacat
     8581 agtttcctaa tcgatagcct tcaacgccga atcttgcgta tttttgcgct aattttgaac
     8641 aatcagttac gttcacagct aactcttcta ctttgcggta accgcttaag atacgttcaa
     8701 aaggttctaa agtgattttt gcttccatat tcttccccgt ccatcttcca catacttcat
     8761 atcatttcac atgatactta tgctctcatc ataccacagg ttgaattaga aaagaaaata
     8821 aatcacacaa aaaagcaaga caatctgtta gtgagattgt cttgcttttc gaaaaagact
     8881 gaatactttt cgttaaaact ggttgcttag tcttctaatg ccacattatg gaacacatgc
     8941 tgtacatctt ctagatcttc cagtgcatca atcatttttt caaatgtttc ttgatcttct
     9001 ggagatagtg ttacctcgtt ttgagggatc atttggatct cagcgattga aaaatcagtg
     9061 attccttttt cttttaatgc ttcttgtata ctatggaaat ccgctacttc accgtaaacg
     9121 atgatttgtc cttcttcttc cattacatcg cgaacatcga tgtctttttc cattaggtat
     9181 tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga ttgctgtatt gtcaaacatg
     9241 taagaaaccg ctccggaaac acccatgttc ccgccatttt tcccaaatgc tgcccgtacg
     9301 tctgctgctg ttcgattcac attgttcgtc aatgtatcaa caatcaccat tgagccgctt
     9361 ggtccaaatc cttcatagcg caattcagag tatgtttcat ctcctgcacc ttttgctttt
     9421 tcgattgctc ggtcaataat atgttttggt acattataag ttttagcgcg atcaatgacg
     9481 aaacgtagtt tttggtttgc atgcggatca ggatcacctg attttgctgc cgcgtagatt
     9541 tcaatcccaa attttgcata aatccggcta ttattagcat ctttagcagt tttctttgct
     9601 acgatatttg cccatttacg tcccatattt tcacttcgct ttctgatttg atagtttcat
     9661 aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg attctgtgaa gctttttttc
     9721 tttcttcctt cattcttctc atttttagtc aattatctat actcggattg ggatttgccc
     9781 gaaattctgt tccggaatat tgcctcccaa ttgatagatt tgatcacttc taactaacag
     9841 ttccgcttct tgtgcctctt tttttccgat tcgggaataa atagaaatct cttttttttc
     9901 ttttaagaat cttcttccag catcggtaaa tccaagtagt cgaagataat ttttattttg
     9961 ttggacagga atctcttgct ttttgatatt cagcaagaca taacaagata atcgttggat
    10021 ccgtgtccat gtatatcttt ttgtttttac ctttgacaca aaatcctcaa aactatcagc
    10081 agttgcagct gctgttttca tgcgcgattc tattccttcg gtcatctgat agatatctgt
    10141 cagttccagc aaagtagaag ataacaaccg ataacgcaaa tacggccaat aagattccca
    10201 agtctgcagc gaacaagttg aaagatcttc ttctgtctga ggcggcacaa gtccagctat
    10261 tctttttcct tcttctaacg catggcgaat ggctgttgca ctggctatcc tctgatctgt
    10321 gatgattttt tcatgatagc ctgcactttt acgtcggatc ggatgtaatt ccatagggtg
    10381 gacatacttg gcattttcct ttgcataact taatcccaag atatgatttg gcgaagaaaa
    10441 atcaagcgta atatcgggat acagactgcg aaaaacctca gtcatttttt gcggataact
    10501 atacgtttga tcagacagtt cttgaaatgc ctcttctatc ctatcttgat tctcttggac
    10561 aaagcgtccg aaactgctgt aatcaaacga agtctcttct tctgttccaa aacacaaact
    10621 gtcacagtcc agtgtttgca agatttttac tgcaccttta gcaaaatagt cagctgactg
    10681 aaccgcccat tcgacgggaa gctccactac taaatccaca ccattttgta aagcttcatt
    10741 cgcgcgatgc catttatcga tgatagccgg ttcgcctctt tgcaaaaaat tcccgctcat
    10801 tacagcaatg acgacctctg ctcctgttat ttttcgtgcc atttccacat gatagcgatg
    10861 tccattgtga aaaggattgt actctacgat aatcccgcag cttttcatgc gcatcctcct
    10921 tcatagttat cgataaaaaa gaaatagaga caagtaaaaa aaggcaaaaa tcggaaaaaa
    10981 tacccgaact atataaacta ttctcgcaaa cacaatactt ctgcgacgaa aagctgcact
    11041 gcaagagcaa tgcctatatc gttcggatat ataatttatg ttgaagattt attcttttct
    11101 tgttaactcg agcaggcaaa accgctagtc tttgtatgct acaaagaacc agcgctttga
    11161 tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct tcgactttcg aaaagccgct
    11221 gttttccagc attcttaaat aactttccaa tggataggta cgctcttgat gtagttcatc
    11281 ttcacgaata aatcgaccag acccttcttg ttcttcaacg aaaaaggtaa gaaaatgttc
    11341 gatgctgtgt ttctcgcttc ctggataact atcccacaaa aaagcaaaat tatccccttg
    11401 ataatgatag ctatattctg gaaaaacctc atctacttga taggtggagt gtacgtcaaa
    11461 taaaaatcgg ccattttctt ctaacgcttg atagacttca tcaaacactt gctgtacctc
    11521 ttgtctattt ttcatatagc acagcgaatc agaaaaacag gtaattgcct gatattgtcc
    11581 gatttctgat aaatcgagca tattgccttc cacaaattgg atcgatgcgt cttcttcata
    11641 tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg tctaaccctg tcactttata
    11701 tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg catgccagtt ccaaaatatt
    11761 ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac cattgctgat aaagtgtttc
    11821 gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa gccatatgtt aatccaacca
    11881 ttcactaaga tcgactagcg gagcatctga ccatagtttt tccagattat agaaatttcg
    11941 ttctggcgca tggaaaacat gtacgatcac atctccaaga tcgatcaata cccattttcc
    12001 gccttctttt ccttcaatac gttttacttc atatttgttt tcttcttctt tatcaatgat
    12061 ttcttctgta attgcgttga tttgacgttc gctatttgct gaacagatca tgaaataatc
    12121 tgccaacaag gaaacatttc gaacgtctaa agcgataatg tcttctgccc gttttgaatc
    12181 tgctgcttca atcgcaattt ttaattgttc tttactatct atgatgattt cctcctaata
    12241 tgagcagctt atttttttgc tacccagtaa ttatatgttt cgattgtttt tggataaatc
    12301 tgttgttctt gcgcaagcaa atgggccaat gtatgttttg tttcaaatgc tacagcttcg
    12361 tctagatcag cccatgcaat ggctcgtgca tcttgtaccc caggaaaatc tcgacctggt
    12421 tcaatatagt ctgctacata aatgattttg tcaaggagac tcatcttagc agccccagtc
    12481 gtatgcaccc ggattgcatg aagaatctct gcatcggtga ttcctaattc ccgctctaca
    12541 aacgaagcgc caacaagacc atgccagatt gcattattat aattcaataa ctccggatca
    12601 aaaccgtctc ttacgattac cattttgaac tcctcatctg gtcgttcttt tgcataatca
    12661 tgtgtcaatg cagcaatact agctttttca ggagaagcac cgtatttttt ggcaagagcc
    12721 acggctgttt cttctactcc aagcacatgc ttgaagcgtt gttcgctcat tctcatctgt
    12781 attttttgca tcaggttttc tctagaataa gcagtatatt cattactata gtccatattc
    12841 atacaaccct tcattttgaa tataatcaat tactttatct ggaacaaggt agcggataga
    12901 acagccttct ttgatctttt gacgtatttt cgtggaactg atgtcgatct caggtacatc
    12961 tacccaaatt acaggatatg gagtatccgt tgtgtatcct ggtcgacgta tacccacaaa
    13021 gttgaccata gaagtcagct catcgatttt ataccatttt ggcaaatatt ctaccatatc
    13081 cccaccgata ataaagtaat aatctgtatc cggattgttt tgcgtcaatt ccttcatagt
    13141 atcataggtg taacttttcc caccacgagc taattcaatc gtttcaatct gcaaaaaagg
    13201 attgtcttcc accgctaatt ccaacatgtt gagtcgatgt tttgcatcaa tcgtctgttt
    13261 ctcatcaaca tgaggtggct gataagaagg catcaaaaat acgcggtcaa gacctaaatt
    13321 ccggccagct tgttcagcca tcactaaatg tgcaaggtga acgggattga atgttccgcc
    13381 caagatccct acttgctttt tcttctctaa gaattgaggc atttcttcag gaaataattg
    13441 tgaacgaaca aatgtcttag cttgcgtatt catcatggtc actccttata ttgcttttac
    13501 ttcttttgat agcctttgat acttttcttt tgtggaaggt ttgtataata caataacacg
    13561 tccaatgatt tggacgattt cgcaatctat ttctttttct aatacttgag ctgcttcttc
    13621 tgcaatctca tctgtatttt gaagtaacga tactttgatc agttctcttt tttctaaagc
    13681 ttcttcaatt tgaacgatca ttgctgaatt gatcccacct tttccgattt gaaaaatcgg
    13741 ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt tttcctctta aactcataat
    13801 tttccttctt ccttaaatca atgctttgcg tttcaataca tctacaccct ttggcgccca
    13861 gcccgcaatt actactggcg ctgttacagt gatccagcct agaccggcaa aaacgatgtc
    13921 tgttttttct ttcacagaaa actcaaaacg aacaagctcc ggaaatgcct cgacttcatc
    13981 aggacgagga ggctgtaata atccacctac atgtttttga taaaattcgt ctgctttttc
    14041 cagtttcgtt cgatgaatat ttacatcatt tgacacataa gcaataaatg aagcacgatt
    14101 gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa agtgtttgcc cttcattcag
    14161 ctgataaact ttaggtttga tttcttttaa cggtgcaatg atccgcaaat cttttttacc
    14221 taagtagtgc gccatttgat ggcgatggat aattcccggt gtatcaatca aaaaatgccc
    14281 gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct ggaaactgcg aagttgtgat
    14341 tacatcttgt actcccgctg tatttttgat gatttgattg ataagcgtcg attttccgac
    14401 atttgttact ccgacgatat agacatcccg tccatcgcgg tattcttcga ttttttctaa
    14461 tagttccgtc atctcatgag atttcttagc actagttaat aatacatcta ctggacgaat
    14521 tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat ttagtttttt tcaatgattt
    14581 aggtaatata tccactttgt tcccaactaa aagtactgga ttgtcaccga caaaacggtg
    14641 tagtcctggg attagtgaac cattgaagtc aaaaatatcc accacattga cgatcaatgc
    14701 atctttttgc cctaattcat tcagtaagcg caaaaagtcg tcatccgtca atgagacatc
    14761 ttgggtctca ttataatggc gtaatctgaa acaacgctga caatagactt ccccggaagc
    14821 taaacctttt tccaaagccg tttgcggcgt gtatcctaat tcaccgggtt tgtttgtttg
    14881 tataacggca ccacagccga tacattgtaa ttcttctgtc attcgattcc acctcgccag
    14941 cccatatcag ggtgttttgc taatagatag gccataattc ttttttccca aaaacgatta
    15001 aattgtgtct tccaactatc tgttgcgata atgggtttta caaggatgct acgtatccct
    15061 gcacgattgg ctccacgtat atcagtcata atctgatcgc ctaccattac tatctcatca
    15121 tctgctaaat ccaattgttt ctttgctatg ttgatccctc ttgctaaagg tttcattgct
    15181 cgtgcaacat acaaaagatc aaatttttca atcgctcgcg cgacacgttt tgaattattg
    15241 tttgaaacaa caacaacagg gattcctgca tttttcattt ctaaaatcca agtaagcaac
    15301 tcttctgttc catctggatt attccatgca atcaacgtat tgtctaaatc ggtcaatact
    15361 gctttgatgc ctagattctt taattgggca ggtgtaatct gatagatggc ttctaccatc
    15421 catgttggtt tgtaatttga aaacatgctg tctcctcatc tgcaaaaaat gaaggagcac
    15481 ataaagtact cctcaacccc gtattatact gcatatcagc aaaaaaaact acctctatac
    15541 tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac caaaaataaa gattgatcac
    15601 agaaaaattt agaaacaaaa aacaactaat attggcggaa cctcttgtat cgtttttcca
    15661 gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct ttcaatcaac gcttttttca
    15721 taatgtgtgc gactttatat cgtggcaact gctcgccgtt gaacgtttca ggaataactc
    15781 gatcaacgat tcctaactcg cgtagttctg gcgcagtaat tttcatcaac tcagctgctt
    15841 ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa tccttctgga gaaagcacag
    15901 cataaatcgt ttcttccagc atccagactt catccgctaa acctagagca agggcaccgc
    15961 cacttccacc ttcaccaatg atgatggcga tgatcggtac ctttaaatca gacatttcga
    16021 gcagatttct ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca ccgcaatatg
    16081 cacctgctgt attgatcaag gtaatcaccg gtctattgaa cttttccgct tgtttcatca
    16141 gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc aaaatttctg cggatatttt
    16201 cctgcagatc ccgtcctttt tgaataccga tcactgttac cggtttgcca tctaatcgag
    16261 cgattccacc aacaatcgct tcgtcatctg caaataaacg atcaccatgg cattcctcga
    16321 aagaatcgaa gatctcttca aaaaaatcca agcttgtcca tcgttcttta gctcttgcta
    16381 actgaacgac atcatgtgct gtcttatcca cgatctatcc atcctttctg tgtatgcaat
    16441 tcaagaagcg tatggatttt ctgtttcaat tccatgcggg gaacaatctg atcgacaaaa
    16501 ccatgagata ataagaattc agccttttgg aaatcttctg gaagttcctg cttgatcgtc
    16561 tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc tagaataata
    16621 tcgccttcca ttgcaaaact ggcagttact cctccggtcg tcgggtccgt taaaacagtt
    16681 agataaaaaa gaccttcatt gctatgccgt ttgacagcag cagagatttt tgccatctgc
    16741 attagagaaa agattccttc ttgcatccgt gcgccacctg aagctgtgaa caagacgact
    16801 ggaagacttt cctttgttgc tcgttcgaat aatctggtga tcttttctcc gacaatcgtt
    16861 cccatacttc ccatgataaa attaggatcc atcactccaa taatgaaggg aatcccctga
    16921 atggttgctt taccagtgag gactgcttca tgaagtcctg ttttatcttg cattttttta
    16981 attttttccg tatattcggg aaatgctagc ggatctttgg ttacaagatc cgtatcccat
    17041 tcttcaaaac ttttttcatc aataatcaaa gctagacgct gccatgcacc gattcgaaaa
    17101 gcgtatccgc aatgagggca tactttttct tcaccgatgt ctttcgtata aaggatatgt
    17161 ttgcaatttg gacactttgc ccacatgtta tcaggaacag atggcgagtt agcaggtttg
    17221 ctctctctat taggattgat ccgaatatat ttctttttct taaacagagc catctatgcg
    17281 cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa aaatgctgtg
    17341 ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat ccatctgaaa ttctgcgttc
    17401 gtgatgattc cttctgtgat aaattcactt aaggctcgct gcatcttcat taatgcttca
    17461 aaacgcgtat ttccatggac gattattttt gcaatcattg aatcataata tggcgggatc
    17521 gtatatcccg ggtaaactgc actgtctact cgcagtccca tcccacctgc tggaagcagt
    17581 aagttttgga tcttccctgg agaaggagca aaatggaaag caggattttc tgcattaatc
    17641 cggcattcga ttgcgtgtcc ttggaatact acttcttctt gacacacatt caaaggctca
    17701 ccggctgcta tctccacctg tttttttact aaatcgattc ctgtgaccat ttctgttact
    17761 ggatgttcca cttggattcg agtattcatt tccatgaaat aaaaatcgcc ttcttcatcc
    17821 atcagaaact cgatcgttcc ggcattttca taattgactg ctttagctgc tcgaacagca
    17881 gcgtctccta gtgcttctct ttttgtttgt gagatcacta cagaaggaga ttcttccagt
    17941 actttttgat tgttgcgttg taaagaacaa tctcgctcgc ctaaatgaat gacatgacca
    18001 aatcgatcac ctaagatctg aacttctata tggcgagcag gataaatgat tttttccaaa
    18061 tacatatcat catttccaaa tgccgctgct gcttcttgct gagctgaaga aaaatgctgt
    18121 gggagctctt cttttgattg aactttccga atgcctttcc cgccaccacc tgcagctgct
    18181 ttcagcatca ctggataacc aattctgtct gctatttcca atgcttcttc tactgtagat
    18241 aatacaccag tacttcctgg aatgactggg acatttgctt cttgcatcaa ttgacgcgca
    18301 ttgatcttat ttcccattgc atcgatcgtt gcacttttag gaccaataaa tgtgatattg
    18361 cactcttcac acatggaggc aaatcggcta ttttcagata aaaaaccaaa tcctggatga
    18421 attgcttcgg cttttgtcac gattgcagcg ctcagtactt cctgaacatt cagatatgaa
    18481 tcaacggctt ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt atgaagtgct
    18541 tcggcatctg cttctgaata tatcgctacg gtttggatcc ctagttcgcg gcatgcacga
    18601 atgatacgta cagcgatttc accgcggtta gctatcaata ctttagaaaa catatttcac
    18661 ctatccaatc ataaaggtta attccgcttc ggctactttt ttaccgtcta ctttagcgat
    18721 tcctttgcct attccggctg aagctttcac tttcaatatc tcaacttcaa ggtataaggt
    18781 atctcccggt gtaactttct tacggaattt tgctttgtcc aatccgccga aataagccgt
    18841 ctttcccttg aattgttcaa gagaaagtaa tgcaactgct cctgcttgag ccattgcttc
    18901 aacaatcaat acccctggca taacaggttc ttctggaaaa tgtccttgaa aaaagggctc
    18961 attgatcgtt acatttttct tagcaacgat ccgttctcct tcaaccattt cttccactcg
    19021 atcaatcaaa agcattggat aacgatgtgg aatgatttct tttatttctt gtatgttcat
    19081 tgttttccct ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg gctgtccata
    19141 ttcgacaact gactcgtttt ctacaaggat ttctgtgatc actccgtcgg cctcactagt
    19201 tatctcattc atcagtttca tcgcttcaat aatgcagata acttctcctt tggcaacttg
    19261 atcacctact tttttgaaag ctggtttgtc gggcgctggt tgcagataaa cgattcccac
    19321 gattggcgaa acaacctcga ttccatcaaa tactgccgat tctttttctt tcattatttc
    19381 tggagcagtt gttgcttgtt caggtatgac attgactggc tccgaaactg gcaacgtttc
    19441 gtttgtttga accatattca tgcctcgact tgttttattt ttattcatat acaattcaaa
    19501 ttgaccttca cgcaaatcga attccgttag cgaggattga tcaaattgac tgactaattc
    19561 tctgatttca ttgatatcca aaattattcc tcccagcgtt tcatgcacag aaccgcatta
    19621 tgtccgccaa accctaatga attactcatt gcataagtaa aacttgcagg tttgctttcg
    19681 tttttgacaa ctgtcaagtc aatctcagga tcttgttttt ctacattgat cgtaggtggg
    19741 ataaattgat gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc ggctgctccc
    19801 aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa attttcacct
    19861 aatgcgattt ggattgcttt tgcttctgcc tggtcattgg ctggtgtact tgttccgtga
    19921 gcattgatat atccgacttg ttccggctgt acaccagctt cttccatcgc aagcttcatt
    19981 gctttagatg caccagaacc atctggagta ggagctgtca tatggtaagc gtcacagttt
    20041 gcaccgtatc caacgatttc tccatagatt ttggcaccgc gagcttgtgc atgttctaaa
    20101 gattcaagaa ctagaacgcc tgctccttca cccatcacaa aaccattccg attttcgtca
    20161 aacggaatcg aaccacgatt aggatcagtt gattctgaga gtgctgttaa agctgcaaat
    20221 ccagcaatcc ccatctcaca aatcgttgct tctgttcctc cagcaagaat gacatcagaa
    20281 tagccatgtt tgatgttacg gaatgcttcc ccaattgaat tcgttccgct agcacaagct
    20341 gttacgatag ctgtacaaat accttttgca cctacacgca aagcaatatt tccagctgcc
    20401 atgttggcaa tcgccattgg tacgaacatt ggagaaactc gttttgcacc tttttcatgt
    20461 agacgaataa cttggttttc gattgttgga agaccaccga tcccagatcc gatgatgacg
    20521 ccaaaccggt cttgattcat tttttcttta tctaaaccgc tcatctccat tgcttctaaa
    20581 gcagcgtaga ttccatagat cgaaaacata tccattcgtt tgctatcttt tttaataaaa
    20641 tatttatcgt aagggaaatc tttgacttca cccgctaagg taatccctgt ttctgaagca
    20701 tcaaatttag tgatcggtgc gatgccattc gtcccctctt ttaagctatt caaaaagctg
    20761 tctgcgtcat ttccaatagg tgaagtgact ccatagccag taattaccac tcgattcatt
    20821 tgtttgctct ccttttctta tccgtgcatg accaatccgc catcgacatt gatgacttgt
    20881 ccggtgatat atggattttg tgctaagaaa actgctgttt gtgcaatatc ttctacttgt
    20941 ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct tgactttgtc tgctaaaact
    21001 tccgtcatat cagttgtgat gaatcctggc gcaatggcat tacatgtaat gcctctagtt
    21061 gcagcttctc gtgccacaga ttttgttaat cctactacgc cagctttact agctgcataa
    21121 tttgcttgac caatatttcc aatcaaccca gatacactag agagattaat gatggcccct
    21181 tctcgctgct tcatcatttt tttcaatacg tgctgcgtca tattgaaggt tccaatcaaa
    21241 ttgatatcca gacatttttt gaaatcttct gcatccattc gcatcacaag tttgtcattt
    21301 gtgattccgg cattgtttac taacacatgg atcgatccaa gcttttcttc tgcttctttg
    21361 atcatttgtc ccgctttctc ataatcagag atgtcaccgg aaactcctac gcattttaca
    21421 ccgaatgctt cgatttcttc tatcttttct tttggaatct ctccgcgacc attcaaaatg
    21481 atatttgctc cagcttttgc aaaagctaag gccatcgctt tgccgattcc tcttgtacta
    21541 cctgtgataa atacattttt tccttttaca tccataacgt tcctccttat agtattgcta
    21601 ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac tggtattgtt ttatcgattt
    21661 ttttcataaa tccgcttaat acttttccgg ggccgacttc gatgacttgt tcgatgccga
    21721 ttgtttttaa cttatggata ctctcataga aacgaacagg ttgcatgact tgctgttcaa
    21781 gtagtcccgc gattgtttct ttcttcatta tttccgttgt tgtgttgctt atgataggaa
    21841 aagaaggttc agagaattga atctgactta ggtccttcgc cagttttttt gctgccggtt
    21901 ctaaaatagc tgtatgaaaa ggcccgctga catttagagg gatcattctt ttgaaccctt
    21961 tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca atcacgatct
    22021 gctgaggtgt attataattt gcaggagata cgatgccgta cttgctagct tcatgacagc
    22081 tttcctcgat cgtttcaatc ggcgcattca tcactgcaac cattttcccg cttccagctg
    22141 gggcagcttc tgtcatataa gcgcctcttt ttgctactaa cgcaactgct tcagtgaagg
    22201 atagcgcatt actagctact aatgccgaat attctcctaa actcagtcct aaagctgcat
    22261 ctgggatgat tccatgctcc ttcaataagc gataatacgc gatgctgact gttagaatag
    22321 ctggctgtgt atattgcgtc tgatccaaac gttcattttc tgtaaagcaa agttcagcca
    22381 tatcgtagcc gagaatctca cttgcttcat caaatgtctg ctttacaacg gcttcttcat
    22441 ataaatcttt tcccatacct tgatattgtg caccttggcc actaaataag aatgctgttt
    22501 tcatgttttt ctccaatata tccagaatat atgtttgatt cttcctattc aaaaaggccg
    22561 agacattcct atttcaggaa atgtcccagc ccccaaccta attttaatga ttatgcagtt
    22621 tgtttttcta cgtaagtcac taaatcttga accgttttga ttccgtcttc tgtttcgatt
    22681 ttcacgtcaa attcatcttc aatttcattg atgatttgga ataaatccaa gctgtcagct
    22741 tctaagtctt cttggatgtc agtagtcaat ttgatttctt cagtttcttt tcctaattct
    22801 tctgcgatga tttcttgaat tttttcgaat accataataa tatattcctc cgatattgtt
    22861 tgctttttat ttttataatt taacagtcta caactccatg agaatacttc cccatgttaa
    22921 acctccgcca tagcctgtaa atattacttt ctgctgtttt cctaaggtga tctttccact
    22981 agaaactgct tcatccaata agatagggat gcttgcagca gatgtattcc catatttatc
    23041 catattggtc aggaactttt cttgcggcat ctttactttt cgggcaattt tctcaataat
    23101 tctgaggttt gcctgatgca aaagcagata atcaactggt ttgtctttca tgacttcttg
    23161 gatattgttt gcaacgtctc gtacggcaaa atcaaaaata tctctgccag tcatttgcaa
    23221 ataatacgaa ccttctgaat cttctgaata gaacggattt ttattttgct ggtagccagc
    23281 ggtcaatgag ctacttctgg taccgtcagc tgctaatttt tctttcagca attttttctg
    23341 tggattcgct tctaagagaa tcccacctgc tccatcgcca aacaacacag cagtcgtacg
    23401 atcagaccaa tcgattagct tagatagtgt ttcaccacca atcaccagtc ccttagttga
    23461 gccgcagcgg atcatttttt cagccatgct taacgcataa acaaatcctg agcacgcagc
    23521 actgatatca aaagcgatag catgagttgc tcccaatttc ccttgtactt gtgctgctac
    23581 agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca aatctttagg
    23641 gtttagattt ttctgtttta tcaatttttc cgccactaaa atgcataaat cagaagtctc
    23701 ctgatttgtt acacatcttc gttcacgaat acccgtcctt gacgaaatcc attcatcaga
    23761 ggtatccatc atcttggaaa gatcattatt agtaataatc ttttcaggaa ggacgctggc
    23821 tgttgcagta atcattccaa attgttccat taaatatcct cacttatagt cttgcaagaa
    23881 gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt tcctccgtag ccattccgtc
    23941 taagatgttc ttgaccattt cacgatgaaa atgctgatgg acccgaaata gtaactttcc
    24001 ttttttcgtt agtcccaact ttacaacgcg gcggtcatct tcactgcgga tacgttcgac
    24061 atagcctttt tttactaact tgttaatagc agtggtcaag gtcccaacag taattgatag
    24121 ttctttggct acttctgaag ttgttttttt cttgtacatc ccgattgcct cgatcgtgtg
    24181 catctctgtg attgacagat ctttgaattg agattttttc agctcagact cttcgattgt
    24241 caaaatatca ttgaagacac taacaagata atcatttact gtttttaaat ctggttccat
    24301 gttccaccgt ccactaatta gtttgattat caaatctttt gatgttcaaa ctatatctta
    24361 acttttttca aaatgcaacc ttaaaagatc atttttttac tatatgagct ttttttaaga
    24421 ttttactcat ttaaaacaac
//
LOCUS       DACCVH010000034        24259 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.034, whole genome shotgun sequence.
ACCESSION   DACCVH010000034 DACCVH010000000
VERSION     DACCVH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.034"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="IVV98_001456"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="IVV98_001456"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP7807122.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2485)
                     /gene="purK"
                     /locus_tag="IVV98_001457"
     CDS             complement(1352..2485)
                     /gene="purK"
                     /locus_tag="IVV98_001457"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP7807123.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="IVV98_001458"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="IVV98_001458"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP7807124.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="IVV98_001459"
     CDS             complement(3373..4680)
                     /locus_tag="IVV98_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP7807125.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="IVV98_001460"
     CDS             complement(4683..5264)
                     /locus_tag="IVV98_001460"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP7807126.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="IVV98_001461"
     CDS             complement(5836..7128)
                     /locus_tag="IVV98_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7807127.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="IVV98_001462"
     CDS             complement(7125..7748)
                     /locus_tag="IVV98_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807128.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="IVV98_001463"
     CDS             complement(7751..8587)
                     /locus_tag="IVV98_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807129.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="IVV98_001464"
     CDS             complement(8604..9491)
                     /locus_tag="IVV98_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807130.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="IVV98_001465"
     CDS             complement(9507..10790)
                     /locus_tag="IVV98_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7807131.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="IVV98_001466"
     CDS             complement(11473..12156)
                     /locus_tag="IVV98_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP7807132.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="IVV98_001467"
     CDS             complement(12174..12791)
                     /locus_tag="IVV98_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP7807133.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="IVV98_001468"
     CDS             complement(12801..13625)
                     /locus_tag="IVV98_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP7807134.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="IVV98_001469"
     CDS             complement(13618..14178)
                     /locus_tag="IVV98_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807135.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="IVV98_001470"
     CDS             14352..15308
                     /locus_tag="IVV98_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7807136.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="IVV98_001471"
     CDS             complement(15613..16569)
                     /locus_tag="IVV98_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP7807137.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="IVV98_001472"
     CDS             16673..17275
                     /locus_tag="IVV98_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7807138.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="IVV98_001473"
     CDS             complement(17363..18862)
                     /locus_tag="IVV98_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP7807139.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="IVV98_001474"
     CDS             complement(18878..19402)
                     /locus_tag="IVV98_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807140.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="IVV98_001475"
     CDS             19700..20449
                     /locus_tag="IVV98_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP7807141.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="IVV98_001476"
     CDS             20440..21225
                     /locus_tag="IVV98_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7807142.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="IVV98_001477"
     CDS             21194..21910
                     /locus_tag="IVV98_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7807143.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23031)
                     /locus_tag="IVV98_001478"
     CDS             complement(22012..23031)
                     /locus_tag="IVV98_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP7807144.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23050..24108)
                     /locus_tag="IVV98_001479"
     CDS             complement(23050..24108)
                     /locus_tag="IVV98_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP7807145.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7624 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgtaa agtgatttt
//
LOCUS       DACCVH010000035        23829 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.035, whole genome shotgun sequence.
ACCESSION   DACCVH010000035 DACCVH010000000
VERSION     DACCVH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.035"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(53..787)
                     /locus_tag="IVV98_001480"
     CDS             complement(53..787)
                     /locus_tag="IVV98_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP7807146.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="IVV98_001481"
     CDS             1114..1524
                     /locus_tag="IVV98_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP7807147.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="IVV98_001482"
     CDS             1517..2218
                     /locus_tag="IVV98_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP7807148.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="IVV98_001483"
     CDS             2218..3804
                     /locus_tag="IVV98_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7807149.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="IVV98_001484"
     CDS             3823..4044
                     /locus_tag="IVV98_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP7807150.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="IVV98_001485"
     CDS             4041..4802
                     /locus_tag="IVV98_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP7807151.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="IVV98_001486"
     CDS             5182..5691
                     /locus_tag="IVV98_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP7807152.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="IVV98_001487"
     CDS             complement(5766..6305)
                     /locus_tag="IVV98_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP7807153.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVV98_001488"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVV98_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP7807154.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7372..8169
                     /locus_tag="IVV98_001489"
     CDS             7372..8169
                     /locus_tag="IVV98_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP7807155.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8197..8832
                     /locus_tag="IVV98_001490"
     CDS             8197..8832
                     /locus_tag="IVV98_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP7807156.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="IVV98_001491"
     CDS             8852..9625
                     /locus_tag="IVV98_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7807157.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="IVV98_001492"
     CDS             10033..10830
                     /locus_tag="IVV98_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP7807158.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="IVV98_001493"
     CDS             10808..11221
                     /locus_tag="IVV98_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807159.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="IVV98_001494"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="IVV98_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP7807160.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="IVV98_001495"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="IVV98_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP7807161.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="IVV98_001496"
     CDS             15998..16558
                     /locus_tag="IVV98_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP7807162.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVV98_001497"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVV98_001497"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP7807163.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="IVV98_001498"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="IVV98_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP7807164.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="IVV98_001499"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="IVV98_001499"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP7807165.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="IVV98_001500"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="IVV98_001500"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP7807166.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="IVV98_001501"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="IVV98_001501"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP7807167.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="IVV98_001502"
     CDS             21905..22483
                     /locus_tag="IVV98_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP7807168.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="IVV98_001503"
     CDS             22535..23017
                     /locus_tag="IVV98_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP7807169.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="IVV98_001504"
     CDS             23134..23508
                     /locus_tag="IVV98_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807170.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5116 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaagtgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DACCVH010000036        23647 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.036, whole genome shotgun sequence.
ACCESSION   DACCVH010000036 DACCVH010000000
VERSION     DACCVH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.036"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            14..646
                     /locus_tag="IVV98_001505"
     CDS             14..646
                     /locus_tag="IVV98_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807171.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(780..905)
                     /locus_tag="IVV98_001506"
     CDS             complement(780..905)
                     /locus_tag="IVV98_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807172.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1039..1932)
                     /locus_tag="IVV98_001507"
     CDS             complement(1039..1932)
                     /locus_tag="IVV98_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP7807173.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2114..3040)
                     /locus_tag="IVV98_001508"
     CDS             complement(2114..3040)
                     /locus_tag="IVV98_001508"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP7807174.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3125..3886)
                     /gene="pflA"
                     /locus_tag="IVV98_001509"
     CDS             complement(3125..3886)
                     /gene="pflA"
                     /locus_tag="IVV98_001509"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP7807175.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4130..6361)
                     /gene="pflB"
                     /locus_tag="IVV98_001510"
     CDS             complement(4130..6361)
                     /gene="pflB"
                     /locus_tag="IVV98_001510"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP7807176.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6638..9088)
                     /gene="parC"
                     /locus_tag="IVV98_001511"
     CDS             complement(6638..9088)
                     /gene="parC"
                     /locus_tag="IVV98_001511"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP7807177.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9100..11145)
                     /gene="parE"
                     /locus_tag="IVV98_001512"
     CDS             complement(9100..11145)
                     /gene="parE"
                     /locus_tag="IVV98_001512"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP7807178.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11311..11745)
                     /locus_tag="IVV98_001513"
     CDS             complement(11311..11745)
                     /locus_tag="IVV98_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP7807179.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11872..12510
                     /gene="plsY"
                     /locus_tag="IVV98_001514"
     CDS             11872..12510
                     /gene="plsY"
                     /locus_tag="IVV98_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP7807180.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12642..13517)
                     /locus_tag="IVV98_001515"
     CDS             complement(12642..13517)
                     /locus_tag="IVV98_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP7807181.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13599..14390)
                     /gene="codY"
                     /locus_tag="IVV98_001516"
     CDS             complement(13599..14390)
                     /gene="codY"
                     /locus_tag="IVV98_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP7807182.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14408..15808)
                     /gene="hslU"
                     /locus_tag="IVV98_001517"
     CDS             complement(14408..15808)
                     /gene="hslU"
                     /locus_tag="IVV98_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP7807183.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15822..16370)
                     /gene="hslV"
                     /locus_tag="IVV98_001518"
     CDS             complement(15822..16370)
                     /gene="hslV"
                     /locus_tag="IVV98_001518"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP7807184.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16407..17312)
                     /gene="xerC"
                     /locus_tag="IVV98_001519"
     CDS             complement(16407..17312)
                     /gene="xerC"
                     /locus_tag="IVV98_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP7807185.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17510..18886)
                     /gene="trmFO"
                     /locus_tag="IVV98_001520"
     CDS             complement(17510..18886)
                     /gene="trmFO"
                     /locus_tag="IVV98_001520"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP7807186.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18855..20933)
                     /gene="topA"
                     /locus_tag="IVV98_001521"
     CDS             complement(18855..20933)
                     /gene="topA"
                     /locus_tag="IVV98_001521"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP7807187.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21055..21912)
                     /gene="dprA"
                     /locus_tag="IVV98_001522"
     CDS             complement(21055..21912)
                     /gene="dprA"
                     /locus_tag="IVV98_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP7807188.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21968..22735)
                     /locus_tag="IVV98_001523"
     CDS             complement(21968..22735)
                     /locus_tag="IVV98_001523"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP7807189.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22728..23588)
                     /gene="ylqF"
                     /locus_tag="IVV98_001524"
     CDS             complement(22728..23588)
                     /gene="ylqF"
                     /locus_tag="IVV98_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP7807190.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT         6146 a         5108 c         4072 g         8321 t
ORIGIN      
        1 atttggagat attatggaaa ttcaacgtag aaccactaat tttttacatt taggctcttt
       61 ttttgcaact ttgacgatct tattttttct atgttattca taccttaaga cctcacatgc
      121 gccttctagt gcattaggct ggttgctttt ggatcattct gatatcacag aagccgaaga
      181 aaatccgttt tttttgattt tgtcttctct ttgcggctta ctgttttctg tttatttcgg
      241 tgcctatttt tttcatcgac atcctggtac gttaaacgaa gcttcaagcg tattgattgc
      301 atttaaaacg ttttcttttt tagcaattct tttttattcg tttaatcaca atacgctttt
      361 cttctttatc atgaatggtt tagtcgtgat tttatccatt tttacttatt ttattttttc
      421 actcattttt agccaattga aatgtccgct cttctttcga ttagttcctg tcacctgttt
      481 tatttacagc ttgttttcct tttttgtcct tgctttaatg ccactgacca acccttcgac
      541 gatccaagtc gcaggaaatc tgttggatat gctcttcatc gtcagtctag gtgtatttat
      601 gtggcaaaga aaaaacaaac aaaataaaaa gcattttgaa gcctgactat tacgacttca
      661 taaatgcttt tttagtttta aacacttcaa tctaaaagaa taacccaaga ttggataaat
      721 tattaatgac tcgccattcg tttcttagtg attctggatt atcaaatgga cttcctaatc
      781 taatcagcta gttcttccca taaaatgcca tacttgactg aatcataata ttgattattt
      841 aaaaatctaa cttttcttat cactacttcc tttgtcattc cacatttctc accatttttt
      901 tgcattcctt tgtttccaga ccatgtagtg aatctaatag gtggtagata ggcaaaatac
      961 tcaaataatt cttttaacca taaaggaaga gaaaggctcc tcctgcaaga gtcagtataa
     1021 tttttgctta ctgctctctt aggttttact cactaaaact gttccatatt ctttgatata
     1081 agaaaatgca tgcggtataa atttcttgct cagctcagaa aagatttgtc gtttaagaaa
     1141 ggccatttcc tccattgtca atgaaggatc caatgttggt aattcaatct caaaattgtt
     1201 tttttcgaca ataggtaatt ctaatgtgaa tgattcttct tcctttatag tattcgtcac
     1261 aagtagagac tgatggaaaa tactaggccg gcgattttta tatttattct tacgtatcct
     1321 gtcaacgata acttctattt gatcaaaaaa gtacgattca tttacgtctc caataagttc
     1381 ggctaattct ttgaatgcct tcgttacagg aagctgattc ttctgtacaa aaaagtaatt
     1441 agccaaagta agcgggaagt gttctataga ggaaagtgtg ataaaacggt acttctcatt
     1501 tcctgcagtt gtcctcagca attctgtctc tcggctgttt cttactccat aaaaatacgc
     1561 ttctttccgt tcatcttcga aacaatacgc ccaaataact tctcccatcg ctaatttttg
     1621 ttcatcaaca gagagtctct tcaattgttc agctatggtt tcagcagccg aagtggcttg
     1681 ttgcaagtaa tctttaggat caaatattgg aaagttcaaa tgatatcttc gttcttccct
     1741 cttgattaat cctgcatcga tcaataaatc aagaaaatgg gaaaatttat tttgcgaaaa
     1801 ttcttttttc aattctctta gaatcgtttc ttgttctcga tgttcatata gataatcggt
     1861 caatgaagaa aaaagcggat catcggtcag tttttgataa aagttttcct tattttttga
     1921 ataatagttc atatatgttc tcttttctat ccgttttatt ttacttaaaa ggcttttacg
     1981 taaaaaggag gaagaacaag agtcataatt gactgttatt ctcctccatt tcttcggcct
     2041 ttagtatgtt ctatgtttct ttttatatca atcgcttatc cattcatttt gaatgcttca
     2101 tactaccatt tgattagcta aatacagccg tcaattgagg tacgacttgt tttttacgtg
     2161 aaacgacacc tttaagcaaa gcacggttgt tggtcaaagt tgtttggaaa gcttcttcta
     2221 ctttttcttt tcctttacca gcaacaagta attctgaatc actgtctaag atgtttgtga
     2281 caactaatac gaacagatcg tagccatttg ctttcatttc atcttccatt gctgcttcta
     2341 gctctgcttg tcgatccatc acttcattaa ggtccactgt attgacttga gcgatacgaa
     2401 cgttggaact gcccattggg aaactttttg catccaaatc aagaagaacc gcagctgatt
     2461 tatcacttag atttgttcct gctttcaaca tttcaagtcc ataagtgttt agatcgactt
     2521 cagcgattgc tgcaagttct tttgcagctg cttcatcttc aggcgtacat gttggtgatt
     2581 tgaacaacaa tgtatctgaa atgatagctg agagcatgat tcctgcgatt tctttaggaa
     2641 ttgttacttg gttttcttta tatagtttta aaataatcgt acttgtacat ccaactggtt
     2701 ctgcacgata gtacaatgga ttagctgttt caaagtttgc aatacgatgg tggtctacta
     2761 cagctaaaat atttacttcg ctgatatctg aaatactttg ttggaattca ttatgatcca
     2821 caagcatgac atctgcattt tctgctttag ctgactctac tactcgtggt gcagatagct
     2881 gaaagtggtc taatgcgtat tgtgtttctt cattaggtgt acctagagca actgcttctg
     2941 tttctttacc taattcattt tgcaagtgtg aaaacgcaat ggctgccccg attgcatctg
     3001 tatctggatt ttggtgacca aaaactaaaa tttttgacat gtcattcgct cctttgtgat
     3061 ttctcctatt taataatagc aaaaaaacgg aaagaagcaa tacttatctt ctttccgatg
     3121 cgacctatcg cgttaaatat tttgtatact cttctgtatg aagcaatcgt ttagcatttt
     3181 cgacacgttc ttttgtaggt ggttcgatcc cttctaatgg atatttcaaa ccaagtgttt
     3241 cccacttgta ttttcccatc gtatgataag gaagaatctc tactctgtct acatttgaca
     3301 aggtttgaat aaagttgtct agtcggatca aatattcatc ataatcactt cgctcaggaa
     3361 ctagtacatg gcgaatccaa accggtttgt tgatttttga caaatattga gccatttcta
     3421 aaatattttc attgtcccaa tgcgttagtt ttttatgctc ttcattatcg atgtgtttga
     3481 tgtcaaataa cagtaaatct gtatacttca tcaattcttg aaaacgtgaa aagaaaggtt
     3541 cttcatacgt aaaaggtttt ccgcatgtat ccaatgtagt atgcatcttc cgctcttttg
     3601 cttttttaaa tagttcgatc aaaaaatcga tctgcaatag aggttctcca ccactaacag
     3661 taataccacc tttatctccc cagtaaggtc tgaagcgttc tgctttatct aaaagttcat
     3721 ctgctgtgta ttctttccct ccgccaatat tccaagtatc tggattgtga caaaattggc
     3781 aacgcatgcg gcatccttgc ataaacacga caaagcgcag tccaggtccg tctactgaac
     3841 cgaaagtttc gatagaatga acatagccga ttgttttttc ttccatttaa gttcacatct
     3901 tttctttgat ttcattttaa gtacaagtta gctgtcgaag cgaagctttc tgaacaaaat
     3961 ttttcgcaat tgccgcttcg ttatgtgtaa aatttacagg gacggaacat acaagtcctg
     4021 cccctgtaaa tcgtttcttt caaataagca tactgattat tcgattttga tgcgatggct
     4081 attcaacgtc ctttcgacgc taagtcgaaa aacttttttc acgaactttt tacattctgt
     4141 cgtgtgaagt tctcatcaag acatctaatt gttgttctct tgtcaagtca cggaatttaa
     4201 ctgcataacc agatacccgg atcgtcaagt tcggatattt cattggattt tccattgcat
     4261 cacgcaataa atcattactg aatacattga cattcaaatg ataagctcct tttgagaagt
     4321 atccatctaa gacattacgc aagttttcga ttcttgtatc ttgttctttt ccaagacctg
     4381 aaggattgat tgtttgggta tttgaaattc catccaatgc acagccgtaa ttcattttag
     4441 ctgttgagtt caggctagct aataacccac tttgttccgc attgtaactt ggatttgctc
     4501 ctggcgcaag tggttttcca gcttcacggc catcaggagt atttcctgta tttttaccgt
     4561 aaacaacatt tgaagtaatc gtcaataatg aagttgttgg ttttgagttg cggtaagttt
     4621 tatgacgttt gatttgtccc atgaagtatt ccaagatcca tgaaactaat tcatctgcac
     4681 ggtcatcatc atttccgtat ttagggaagt cgccatccac ttcaaaatca actgctattc
     4741 ctttttcatt acggattgct tttacttttg catatttgat cgctgacaag ctgtctgccg
     4801 catgagagat cccagcaata cctgtagcaa atgtgcgttg caagtcagaa tccatcaaag
     4861 ccagctgagc tgcttcataa gaatatttat catgcatata atgaatgatg ttcaacgtat
     4921 tgacatatag ttctgctaac caatccatca tattcatgaa gttatgtttc acttcttcaa
     4981 agtctagtat ttctgatgtg attggacgat attctggtcc aacttgggcg ccagtcactt
     5041 catcgactcc gccattgatg gcatataata gtgttttagc caagttagca cgagcgccaa
     5101 agaattgcat gtcttttccg acaactgttc ctgatacaca gcaagcaatc gcacaatcat
     5161 cagaacccca ttgttcacga agctgattat cattttcgaa ttgaatcgaa gaactttcga
     5221 tagcgattct gctagcatat gttctgaatc cttctggaag gtgttcagaa tacaaaacag
     5281 tcaagtttgg ttctggtgaa ggtcccatat ttgttaatgt atgaagcaga cggaaatcat
     5341 tctttgtaac taatgaacga ccatctaatc ccatacctgc aatggataaa gtagcccaga
     5401 tagggaatcc tgagaataat tggttatatt caggtgtacg cgcgaatttg accatacgta
     5461 atttcattac taagtggtcg atcaattctt gtgcttcttt ttctgtgatt actccattat
     5521 ccaaatcacg ttggatatag atatcaagga atgctgagat acgtccgatt gacatcgcag
     5581 caccattttg tgatttgatt gctgctaaat atccgaagta tagccattgg acagcttctt
     5641 ttgcatttgc agctggttta gaaatatcat agccatattt cgcagccatt tctttcattt
     5701 gcgctaatgc acgatattgt tcagtgattt cttcacgtaa acgaatcact tcttcactca
     5761 ttgtatgata accagtcata tcatgatctt ttttcttttg ttccatcaaa tagtcgattc
     5821 catacaatgc cacacgacga tagtcaccga tgatacgtcc gcgaccgtaa gcgtctggaa
     5881 gccctgtaat gattttgttt ttacgagcag cacgcatttc agcagtataa gcgtcaaata
     5941 caccttgatt atgtgttttg cgccagtcag tgaaaatatg tgtcaattca tcgtttggtg
     6001 tatagccatt gctttttagc gcattgttag ccatattgat tccgccgaac ggcatgaatg
     6061 cttgtttcaa aggtttgtct gtctgtagac cgacgatttt ttccaaatct ttatccaaat
     6121 agcctgcatc gtgtgaagta atagttgata cgatttctgt gtccatatca tagacaccgt
     6181 tacgctcgaa ttggatatca tttaactttt gcaattcatc ccataatttt tctgttgctt
     6241 ctgttgggcc ttccaaaaag ctgtcatcac cgcgatattc agtgtagtta ttttgaataa
     6301 agtctctagt gtctacgcct tctttccatt tggtaccttt aaatccattc cattgctcca
     6361 ttgtatggac ctcctaaatt tctgttttat gtaacagttt ttacgtgatt agtataacac
     6421 agcaccctat ctttgcaagg gttttcttgt tttttattta acaattttta tgttttattt
     6481 acatatattt aaatcaacgt tgacatacca acatttaagc attgtgaaca ctttcatctt
     6541 tttttgcaaa cgtataagga tttattaaaa atgaatgaaa aagagacgcc acctgtatta
     6601 atacagatgg cgtctcttca ttaaaatact acaacagtta cgactcgatg aaaatctcag
     6661 gagcatcgat aacttcgatg acttctccac cttttttctc atccatcgca aatgatccat
     6721 tcgatgttcg atcacctata gggaaatcag ttgggtcaat cgttaactgc tgcccttttt
     6781 gattcatcaa ggttatttct tttgatcttc cttccgacat atagataata cggtgcggat
     6841 tttttttcag ctcacgcatg accgtcactc cccgcttcgc acgtgaagtt tggctgattt
     6901 cttgagcaag catgcgttta acagctcctc gctgagtaac gattacgatc ggcgtatcac
     6961 cttctgctaa cacaagcagc ccgttgataa tcctatctcc atctttcaaa ttcatagact
     7021 tcactccagc tgcctttgct ccaacaacgg gaacatctgt taaaggatag cgcaaaccca
     7081 ttccttgatg cgttactaag aaaacatcta agcctggctg atcttctttc agatacacag
     7141 caatcagttc atcttcttcc gcctttagct tcatacagct gagcggacgg ctcttatagg
     7201 tgcgccatgg ttcgaactct gtcattcgtg tttgcttgat caatccattc ttgctgatga
     7261 atacaaatgt tttctctgct tgaatttttt gatatgggaa aacagctaaa atcgattcgt
     7321 ctacagacag attggagatt gtttgagaaa tgtgctcacc agcatctttc catttcaaat
     7381 cgggtagttc atggacaggg cggtagatca catttgcttt atttgtgatc agaagaacat
     7441 ggtccaatgt actcaattca cctgagtata gcaagtagtc gccttctcgc atcccgattt
     7501 cttctggttt ggaagcacta taagaacgaa ggcttgttcg cttcacatag ccttctcgcg
     7561 tcacactgac aattacgtct tcttgtgcca ctaagacttg cgtatcaatt ttgatttctt
     7621 cgatttcgtc ttcgattgtc gttagacgag cggaagaata attttttttc acttctcgca
     7681 attctttttt cataacagag aaaagctctt tgtcatttga aaggatttta ttcaactctg
     7741 tgatttgcgc aatcaagctt tcggattcct tttgaagctc tgtgatatcc gtgttcgtca
     7801 aacggtataa ttgcaatgtg acaattgctt ctgcttgttc ttctgtaaat tgaaagacgt
     7861 cgactaaatt ctttttggcg tcttttttgt ctttactttc acgaatcgtt gcgattactt
     7921 catccagaat cgataaagct ttcatcaatc cttctacgat atgctgtctt ttttgagctt
     7981 tggctaaatc gaattgacta cgttttgtta tgacttgctt tcgatgctcg atataacttc
     8041 ttaaaatgtc tttcagtcca acttgatgcg gagtcatatg gtcgatagcg accatattga
     8101 aattgtaatt gatctgtagc tcagtgtttt tgaacaaata attcaaaatt ccttgagcat
     8161 tggcgtcttt tttcaattcg acgacaattt gcagacctgt tctatcactt tcatctcgta
     8221 cttcagctat tccatcgatt ttcttattca aacggatctc atccattttt ttcaccaagg
     8281 tcgctttatt tacttcatat gggatttctg tgatcacgat ttgctgttta ttacccttca
     8341 ttgcctctat ctttgttttc gaacgaagaa taacttttcc tcgtcctgtt tcataagctt
     8401 ttttgatttc atcttttcct tgcaagatcc ctcctgttgg aaagtcaggt ccaggaatat
     8461 attccatcaa tttttcaagg ctcgcttgtg gatgatcgat catatagatt gtgccatcga
     8521 tcacttcagc taagttatga gtcgggattt ctgttgcata tccagcagat atacctgtcg
     8581 atccattgac gagaaggttt gggtatcgag ctggaaggac tgttggttct ttttctgtat
     8641 catcaaaatt ccacacgaga tcgactgttt ctttctcgat atctgctagc atctctccac
     8701 ttaacttgga taatctggct tcagtataac gcatcgcagc aggtggatca ccgtccatac
     8761 tcccgttatt cccgtgcatt tcgatcagta cttcccgcaa cttccagtct tggctcatgc
     8821 ggaccatcgc ttcataaata ctgatgtcac catgaggatg ataattcccc atgatatttc
     8881 cgacagattt tgctgattta cggaatcctt tgtcatacgt attgccatct ttgttcatgg
     8941 caaataatat ccggcgttgc actggcttca atccatcacg gatatcaggc agtgcacgtt
     9001 cttggataat atatttggaa taacgtccga agcggtcacc catcacttct tctaaagtta
     9061 attcttgtac ttcttgtcga ttttccatca ggtgacctcc tattctactt caaataactg
     9121 attgttttca tttttatctg ctcgttcttc atctaataaa tcattagaaa ctgaaggaga
     9181 gatttcagta tcctcttttt tatctaagat actgccatct tcttcgagcg taaattgcac
     9241 gtgattttcg atccattttc ttcgaggttc tactttgtca cccatcagtg tggttactcg
     9301 acgttcagct tgcgcagcat catcgatacg gacgcggatc aacgtacggg aagtcggatc
     9361 catcgttgtt tcccacaatt gttccgcatt catctctcca agtcctttat atcgctgcag
     9421 catatatcct ttgccgactt ttttaatcat tgctgccaat tcgtcatctg tccacgcata
     9481 ttcaatgact tgcttctttc cttgtccttt ggatacttta tataaaggcg gtaacgcgat
     9541 atatactttc ccagcttcaa tcagcggttt catataacga taaaagaaag taagcagtaa
     9601 tacttgaata tgggcgccgt ctgtatccgc atcggtcatg atgattactt tgtcgtaatt
     9661 acagtcttcg atagaaaact caggaccgac tcctgcacca atcgtataga tcatcgtatt
     9721 gatttcttca tttttcaaga tatcttgcat tttagctttt tcggtattga tgacttttcc
     9781 tcgtaaaggt agaattgctt ggaactttct gtctcttcct tgtttagcag atccgccagc
     9841 agaatcccct tcgactaaat acaattcatt tttcttaggg tttcgggatt gtgcgggtgt
     9901 caattttcct gaaagaagag attcgccttt tttacgcttc ttcccatttc ggctttcttc
     9961 tctggcttta cgtgctgctt ctctcgcttc tctggctttg attgctttac ggaccaacat
    10021 ctggctcatt tcgctatttt cctgcaaata aaagcccatt tgttcactga tgacgttatc
    10081 tactacggta cgagcaactg gcgtaccaag tttttctttt gtttgccctt caaattgcag
    10141 aagattttca ggtacacgga tagaaagtac agcagctaac ccttctctga aatcactacc
    10201 ttccagattc ttgtcccgtt ctttcagcaa accaactttt ctcgcatatt cattataaga
    10261 tttcgtcatc gccgctttca taccagcttc atgggttccc ccatcttttg tccgaacgtt
    10321 attgacaaaa gataaaacat tttctgaata accgtcattg tattgataag cgacctctac
    10381 ttcgatacct tctttttctc ctgaaaaata aacaactggt gtcaatgtat ctttttcttc
    10441 attcagataa tcaacaaatt ctttgattcc ttcttcgtaa tgaaaaattt ccttgactgg
    10501 ttcttctcca cgaagatcag aaagagagat tttaacgcct tttagaagaa aggcagattc
    10561 tcttaaccgt tcggctaaaa tttcatatga aaatttcgtt gtactgaata ttgtatcatc
    10621 tggtaaaaaa tggacagtcg tcccgtttgc tttttttgtt tttcctatct ttttcaaagt
    10681 accgtcaggt ttaccgccgt ttttaaattt ctgctgatac tctacgccat ctctaacgat
    10741 cgttacaatt agccatttcg ataaggcatt taccacactg gctcctacac cgtgcagtcc
    10801 accagaagtt ttgtaccctc cttgaccaaa ctttccgcca gcatgcagca cagtaaaaat
    10861 cacttcaact gttggtattc cggaagcatg cattcctaca ggcatcccac gtccgctatc
    10921 tgcaacagtt atactattgt cttcatggat ggtcacatca atctcactgc cataacctga
    10981 taatgcttcg tcaactgcat tatcgacgat ttcatagact aaatgatgca agcctcggct
    11041 gtcagtggat ccaatgtaca tccctggtct ttttctaact gcctctaatc cttccaatac
    11101 ttggatggac gagtcattgt attcgttgtt tacttttttt gccaaggcaa acgctccttc
    11161 aataatactt tgcggcaaaa ccgcaccacg attatcatac tagaaaaggt cgtgaaaaaa
    11221 aagagggtag acgagaaatc aattttaatt atctcctaac cgctttttcg acattcccct
    11281 ctatcgatca tctcttcttt gtggtcattt ttatttttgg ttttctttca acttaccaag
    11341 ttcaatctta atacaacgat ccattacgat atctgtacgt cctgcttttc ttagcatctc
    11401 agctgcttct ttgttttcaa tccctaattg tgcccagaac actttagcat cagttttcaa
    11461 aaaatcacct gctatttcag gtaaaaattc actccgtcta aatacatcta cgatatcgat
    11521 tggatcatcg atttctgtca aattcgcata gactttctcg cctagaattt cttcaccagc
    11581 caataatgga tttactggta tgattttata tccattgtct tgcaatacct gtgcaaccat
    11641 gtaacttgtt cgttctggtt tattgctcaa gcctacgacg gcaatatttt ttgcttcttc
    11701 caaatagttg aaaatcgttt cttgtgttgg attttttaca gacatttctg ccaccccttg
    11761 cttttctttt tattccatct attatacttg tatctttcat tttttcaatt gttcctgtta
    11821 cctattcatg ctaaaataaa ggatagtttt caacttgaaa gagggtaaaa aatgaaattg
    11881 atcttattac ttattttagc atatctttta ggttctattc cttccggtgt ctggattggc
    11941 aaattgtttt tcaaaaaaga tatccgacaa cacgggagcg gtaatactgg aacgaccaat
    12001 acatttcgtg tattaggcaa aacagccggg attgttgtcc tgcttatgga tattttaaaa
    12061 ggtacattgg ctacttgttt gccgatgatc ttccaccttt ctgggattaa ccctctttgg
    12121 tttggggtat gcgccattct tggccataca tttccgattt ttgctgggtt caaaggagga
    12181 aaagctgttg cgacaagtgc aggaatgctt ttaggattta atcctgtatt ttttgtttat
    12241 tcttgtatca tctttatcgt tagtttattt tgtacaagta tggtgagttt gagcagtatg
    12301 atcagtgcag tattgatcac tttatctacg atcgtccttc cttatgtagc tcctgtgatt
    12361 ttggctaagc ccaattggtt actgacgatc attgcctttt tagtttcttc ctttatcttt
    12421 tatcggcata aagacaatat caagcgtatc agaaaccata ctgaaagtcg aatcccgttt
    12481 ggtttgaata gcagcaagaa aaaatcctga tactttttca ttccaaagag ataaaacggg
    12541 agtgtgacaa atcgatgtca cactccctta ttacttacag gatagctttt ttacacacct
    12601 tggtaaacgg tgttccctgc taacttctcg gtcacaacct cttacttcac tgtgatggaa
    12661 tattttgtct tgaagatttc atgggcacct agttgattga tccctacttt ttccatcaag
    12721 tttccactac tgttcaccgt gtcagcgatt ccgcaccacg gttcgataca aacgaaaggc
    12781 gcttcttttg gataaggaga ccagatccct acataaggca tatctttata gcttaaagtt
    12841 acgctatggg aagatttttc acttcgaatg gcgtacgcat ttagacccct tgtttcaaaa
    12901 accaaggcat cttgctcaaa aagttcacga ttcaaagcca gattcgtatt tgtctgacct
    12961 aacgtctttt gatccatatc gatgaatggg cctttcaatg gtaggcgtaa tcttgatttc
    13021 aatggagaaa atgccagata gaaatcttca aatgacaatc cttcttcaag aggtacattg
    13081 aaagcaggat gtccaccgat agaaaagaac atttcttttt caccggtatt tgccacttga
    13141 taatgaaccg tgatgccgtc tcctcctaat tcatagctga tcactaattc aaaatcaaat
    13201 ggatactttt ctaatgtctc cggcgtactc cttaagatga aactagccat ttcttgtcca
    13261 tgttcaatga cttcaaaatc catatcccga gcaaatccgt gttgccccat ttgatatgtt
    13321 ttcccttgat aaacatactg atcatctttt aaacgtccaa caaaagggaa taaaaccggt
    13381 gcatgtctgc cccaatacgc tggatcacct tgccagatat actctaaacc atgttctttt
    13441 gatttcagac tgatcaattc cgcaccgtgt tcagcgattt cggcgatcag ctggtcattt
    13501 tgaataataa cagtcattgc cattcctcca acttcgactt actttttaaa atgggaaggc
    13561 tggaacaaac atttctatct gccccagtcc ccttacttct aataactgtg ttttgctaac
    13621 tcgtctttaa aacgggaatt caatactttt aaataagttc ccttcatgcc taacgaacga
    13681 gattcaatga ttccagctga ttccaatttt cgtaaagcat tgacgatcac agaacgagtg
    13741 atgccgatac tatcggcaat attagaagca gtcagacgac cttcatctcc atccaatgct
    13801 tcaaagatag cttgtacagc cttcaattcg ctataagata atgtgttgat tgccatttgg
    13861 acagccgttg cactccgtac atctgcttcg atgcttcgag acttctgata aaggatctgc
    13921 ataccgacaa ccgtagctcc atattctgct aagactagat cgtcatctgc aaacgattgt
    13981 tccatacgag ataagataat cgtacccaaa cgttcgccag ctccaaagat cggaacgaca
    14041 gtcgtcagac caaatggata tttctctctt gactctaccg gaaatgcagt aatatcacta
    14101 gtaattggga tattagcttc agttttcatc aactgtgcca ctgtatcagt ataagattca
    14161 ggaaattgtt tctcaacaaa cattgttttg attcgttcat tgttcacatc gtgacgttca
    14221 ttataaccta gtaatactcc gtcacttcct atgatatagg tgttgctgtc aagaatacca
    14281 cctagtgtga cagccatttt atcgtaaggc aaatctgctt gcatgtcaaa agtattcttt
    14341 tgctgcaaaa gtgtgtttat cttgcgggtt ttcgttagca agtctgtcat tgtcgtcctc
    14401 cgatttttta taaaatatag cgacttaaat cttcatttgc cgcaattgag ccaagtttgt
    14461 catccacata tgcttctgtg atcgttattt ctcccatttg catatctggt gcttcaaata
    14521 atagatcttc tagtagtttt tccaaaatgg tatgcagtct gcgtgcgccg atattatctg
    14581 tgtcacggtt gacatcgaaa gcgatttgag cgatccgttc aattgcttct tttgtaaacg
    14641 taactgacac attttctgta ccgatcaacg cgacgtattg ttttactaaa gcattatttg
    14701 gttcggtcag aatcttcaca aaatcttcag ctgtcaaatc atctaattct acccgtatcg
    14761 ggaagcgtcc ttgaagttct ggaattagat cacttggttt agacaaatgg aaagctcctg
    14821 aagcaatgaa taggacgtga tctgtttgga tgatcccgta ttttgtgttt acttgtgaac
    14881 cttcgacaat tggcaatatg tctctttgga cgccttctct ggatacttct ccagattgct
    14941 gtgatttaga agtgatctta tcgatttcat cgataaaaat aattccactt tcttccgcta
    15001 atttgattgc ctcactatgg atatcagcat ccttgactaa ttttgctgat tcttccttga
    15061 tcaataactc taaagcttct ttgactgtta ccgtccgttc cacttttttc ttcggtgtca
    15121 aagcacctag agtttcattt aggtcgatcc ccatttgctc caatccattg ttcatcattg
    15181 gtgcaggttt cttttggtct tcaacttcaa tggttacttc acgactatcc agtaaaccct
    15241 tttgtagttg ttccaagact gtacggcgat tgattcgaat atcttctgtc acttcttctt
    15301 gcggttcagc ggtattttgc tgactagcat taaaaagatt catcatttgt tcaaattgat
    15361 tagtggattg tttctgttct tttttgatac caggtaccaa gatttttacc aaacgttttt
    15421 ctgcattttt tttagcactt gtgtatacac ggctgtactg ctctttttct acgatttgga
    15481 tcgcattttc tactaaatcc cgaaccattg attctacatc tcttccgaca taaccgactt
    15541 cagtaaattt tgttgcttcg actttgacaa atggtgcatt gacgattttt gccaaacgtc
    15601 gtgcgatttc tgttttaccg acccctgtag gtccgatcat cagcatattt tttggtgtaa
    15661 tatcttgttg cattttttca tctaactgca aacggcgata gcggttacgc aaagcaacgg
    15721 caacagattt ttttgctgcg tgctgtccta cgatatattc atctaattca cttacgattt
    15781 gtcttggtgt ttgttttaat tcatacatat ctactcacct cttacagttc ttctacgata
    15841 atattatgat tagtaaagat acagatatct gcggcaatat ttaacgcatt ttctgcaatt
    15901 tctttcgcac tcatgtcgtt ttgagcatag tttttcattg ctcgggctgc agccaacgca
    15961 aaattccctc ctgatccgat agctaagata ccatcatctg gtgtgataac ttctcctgta
    16021 cctgaaacaa gaagcatttc tttatcattc attacgatca gcatcgcttc aagtttttgc
    16081 atagattgct gtgtccgcca ttcttgagct aattcgacag ctgcgcgttg tagattcccg
    16141 ttatattcgt ttagtttgcc ttcaaatttt tcttctaaag taaacgcatc tgcaacactt
    16201 ccggcgaaac ctacaacaac ttctccattg tagatacgtc gtactttctt tgcagtgcct
    16261 ttcatgacaa cagattcacc cattgttact tggccatctc cagccatagc aaatttcccg
    16321 tctttttcga cggcacagat agtggttgaa tgaaatggtg attcgaccat gtttgtttcc
    16381 tcctaaattt gttcttttcc ttatttttac gctcttggat ggaaagaacg atagtttttt
    16441 tgtaaacttt cttttgttac atgggcatag atctgggtag tcgataaatt ggcatgtcct
    16501 agcaattctt ggactgtccg caaatctgcc ccattattta ataaatgagt agcaaatgta
    16561 tggcgcagca tgtgaggatg gatatcacta tccaaactgc tttttttgat catttgattc
    16621 aagacatatt caattccagt aggcgtgatt ggttttccat gatgattcac aaaaacgata
    16681 tcatgctctt cgtgatattt tgtcatcaat acctggcggc cttccctgaa atattcttgc
    16741 agagcatctt gagcaaaaga acctagagga gcatatctct ctttgttccc tttaccatgg
    16801 atcaacatga cctctgaatc aaaatcaatg tctgataccg acaaactgct acactcactt
    16861 aaacggatgc ctgacccgta aaggacttcc agtaaagcgc ggttcctcaa atccaaagga
    16921 ctatctcctg ctacgctgtc aaaaagtgct tgcatttcat tttcataaaa aaaacgtggc
    16981 agtctcaaat ttttcttttt gagatgaacg taagaaaatg gattttcttt tatcacttct
    17041 tctttgagaa gatactgata aaacgaacgt aggctggcta tcttgcgact gatagaattt
    17101 ctgctatagc taggacgatg atcagctaat gcactcaaat agacacgaac cgtaaaatat
    17161 tccgccttca gcagatcagc gtctccagat tcctccaaaa aatgtttgaa atggagaatg
    17221 tcttcttcat atgcttcttt cgttttttct gaatatcctc tttcgacaat caaataacgc
    17281 aaaaattttt gttcccacgt ggcttctgtc attttctcac cttccttttg tcccagagaa
    17341 taatttagca cagcgtttat aaaaagacaa ataaattgtc agaatttaac caatatttct
    17401 aagtttgttc acaattggcg caattcctca cattttgttt gagaaattct taagaaaaac
    17461 gcaagaaaaa gagcgagact atccgtctca ccctcttcat ggagtttcct tactcatttg
    17521 ggattgcagt tttttctaat tctgttttta ttgcctcatt agcttttaaa gctcgttgtg
    17581 caattgcttc atatcttgct tttttgtctc gaatgcgctc tggcagttca ggaaacagac
    17641 catagttggc attcatcggt tggaaatgtt ttccttccgc atgagtaatg tagtaagcca
    17701 tacttccaat agctgtttct tgtggaaact cgactggttc catttctttt gctaagcgtg
    17761 cggcgttgat tccagcaagt agtccgctcg ctgcactttc aacatagcct tctacaccag
    17821 tcatctgacc tgcaaagaac agatcttcgc gtttcgttga ttggtaagtc ggtttcagca
    17881 attctggcga attcataaag ctgtttcggt gcatcacacc atagcgaacg aattcagcat
    17941 tttctaaccc aggaatcatc cggaaaacac gtttttgctc gccccatttc aagtgagtct
    18001 gaaagcccac gatgttgtat aaagaagctg cagcattgtc ttgacgcagc tggataacag
    18061 cataaggacg tttgccagtt ttaggatctt ccaatccaac tggtttcata ggtccgaaaa
    18121 gcatcgtttt gaatcctcgc tgtgccatta cttcaattgg catacatcct tcaaaatatt
    18181 tttctttctc aaaagattta agttctgcca cttcggcatt gattagtgcc tcatggaaag
    18241 ctttgaattc ctcttctgtc atcggacagt tcaagtaagc tgcttctcct ttgtcatagc
    18301 gggacttcaa atatacttta tccatatcga tcgtagcttt gtctacgatt ggtgcagctg
    18361 catcatagaa ataaaaacca tctgaaccat tgaatgcttt gatgctttct gctaatggat
    18421 gagaagtcaa aggtcctgtt gctactacgg tgattccttc cggtatttca gtaatttctt
    18481 cgtttatcac tgttactaat ggatgctctt tgacttttcg ggtaattgtt tcagaaaaag
    18541 aatcgcggtc aacagctaag gcaccaccag ctggcactgc tgtttcatct gccgaagtga
    18601 ttactaccga attcaatcgg cgcatttctt ctttcaataa ccctactgca ttagccaaac
    18661 tgtttcctct taatgaattg gaacatacta gttcagcaaa attacttgtg tgatgcgcct
    18721 cagtcgattt gactggacgc atttcatata aacggacagg gactcctgct tgtgcgatct
    18781 gccaagcagc ttcacttccg gcaagccctg ctccaacaac atttaccatt ttcaatgaaa
    18841 gaacctcttt tctattattt ttggatgtct tcttcgtaat ctccatttac acagactact
    18901 tgtttaccgc ctttgacttt cttctcgacc agatatccgt cacattttgg acaatttctg
    18961 cccactggtt tatcccaaga agtgaattca cattctggga aacgggaaca accatagaat
    19021 agtctgtttt tcttagattt tcgttcaatg acttgtcctt catgacatac tgggcaagtc
    19081 acaccgattt cttttacgat tggtttcgta ttccgacaat caggaaaatt actgcaagca
    19141 taaaacttcc catatttccc taattttatc accatcggat gtccacagac atcacaatcg
    19201 aatcctgctg gttcatcttt gatttgaatt ttttcgattt tttcttccgc attcgtcagt
    19261 tctttttcaa acggtttata gaaacgatca accactttga cccacgcttc cgtgccttct
    19321 tcaattttat ccaaatctcc ttccatttct gctgtgaaat ggatatcgac gatttgaggg
    19381 aagaattcac agattaatga attgacaatt tctcctagtt cagtcggctc aaatcttttt
    19441 tgtgtcaatt ttacatagta gcgtctttgg atcgtatcaa gtgttggtgc ataagtggaa
    19501 ggtcgcccta ccccgttttc ttctagtgca cgaatcaacg tagcctcact aaaacgtgct
    19561 ggtggttgag taaaatgttg ttttggttca atatcaacag attggactac atcgccttct
    19621 tcaagttctg gaagaatatt ttctttctct tctttgccgt catctctacc ttccacatac
    19681 acttgcatga atcctttgaa tttgattttt gaaccgttcg caatgaagat gacaccattt
    19741 tgttctaatg tcactttcat tgtatctaaa atagctggtg tcatctgact agccacaaaa
    19801 cgtgaccaga tcaatgtata aagtttcaat tgatctttat ctaaatattg tttgagttca
    19861 tctggtgtac gaagcacact cgttggacgc acagcttcat gggcatcttg tgcgccttga
    19921 gcatttttga tctttcggtg atcatgtcta gaaaattctt ttccatacgt atcttcaata
    19981 aatgctgcgg cctctgcttt tgctgtatcg gcaatccggg tagaatcagt acgcatgtat
    20041 gtaatcaagc cgactgttcc ttgtttaccc aaagtgattc cttcatataa ttgctgtgct
    20101 accatcatgg tttttcttgt tcgaaagttt aacttacggg cagcttcttg ttgcaggcta
    20161 cttgtagtga aaggattcgc agggtttctt ttgcgctctt tcttttctac ttttttaact
    20221 tcgaagtctg ttccatcaat tctagcagtg acttctttta cactttgtgc atctggtaat
    20281 ttctttttct taccgtcgat tccccagaaa tttgctttga atttcttgcg agctttttta
    20341 aaattaccgt cgatgctcca atattcttct ggaacaaatt ctcggatctc tttttcacgg
    20401 tcaataataa tttttaaagc gacagattgg acacgtcctg cacttaaccc tttcttgacc
    20461 ttacgccaga gaataggact gatcgaataa ccaacgattc tgtctaaggt acgacgagct
    20521 tgctgtgcat ctactaaatc tacatcgatc gttcttggtt ccttaaaagc tgctttgact
    20581 gcgtcttttg tgatttcatt gaagaccacc cgattttttt ctttcagatc caacccaagt
    20641 aggtacgcta aatgccaagc aatcgcttct ccttctctat ccgggtcact tgccaagtaa
    20701 actttttgag ctttttttgc tgcggctttc aggcttttga tgacatcgcc ttttccgcgt
    20761 atagaaatat aatggggttc ataattgttt tcaaaatcga tacccatttt acttttcggt
    20821 aaatctctta tatggccaac actggccatt actttatagt ttcgtccaag atatttctca
    20881 attgtcttgg cttttgcagg tgattctaca atcactaaat atttatacgc cattactgaa
    20941 tggactcctt tccattgtcg tgttcctact attaaaagag gattcataca aatcgtagct
    21001 aatcatatcc attcagaaaa cgtttgtcaa gaaaagcaaa tgaaaagtat ggtgttattc
    21061 tttaaattct gccaagatat cttcacccga aaccgtgcaa actgcaccgt cttggatcaa
    21121 atgatgacat ccggtagaat gttctgttaa aatatttcct ggaacagaaa aaactgttct
    21181 tccaagatcc aatgcttgct gtgctgttat cagagagccg ctttttttct tggcttcaaa
    21241 gacacatgtt cctttagaca aagctgcgat aatccgattt ctcattggaa aacaatgctt
    21301 tttcgggccg gattgaggag gatattcact caaaagaaga tgatcatttg caatcacctc
    21361 ttgcaagtca cgattttcag caggatagac ttgctctatc cctgttccaa tgactgcgat
    21421 tgtccgtcca ccatgagaga ttgctgcttg gtgaccgtat gtatctatcc ctttcgcgca
    21481 gccactgacg atcacatatc cagcttctat cactggtttt agtaaataat aaactgtttt
    21541 tttggctaaa gcagaagtgt gtcttccacc aacaacgctt aacatgttac aagaaagtaa
    21601 agatagatca ccattataaa acagtacaat tggcggatag gtcaagtgaa gcagctgagg
    21661 gggatatttg ggatcaaagc aagtgataaa cgactgtttc gattggattt tgccccagtt
    21721 agcgtgaatt tcctgccaac ttttgcgaaa cagctcccgg tgtttggtta ttttacctat
    21781 cttaatgatg tcttcaaatc cgatttcttt ataaggatac tgcatcatcc agttagcaag
    21841 tgcccatttt ccttgactac tgattccttt tgtataagca agtttcaata aattttcttc
    21901 tatttgatac atcataaaac cgcctttcgt ctctctttct aataagatac gtaaaagcgg
    21961 ctgtttttta ttgtaaatat ttttttacag gtgcaaaact tttacgatgg attggcgtaa
    22021 ttccttgtcg ttcaagtcct tctaagtgtt cctttgttcc ataacctgca ttatgcgaga
    22081 aaccatatcc aggataaagc acgtcatatt ctttcatcaa ttggtctcga tatactttag
    22141 caatgatact tgcagcagca atcgacacag atcgtgcatc ccctttgatt attttttcct
    22201 gctgaatagg caaatccaag gtcatcgcat cgatcaacaa atagcttggt acaatggaca
    22261 atttttctac tgcttggatc atcgctaatt tacttgcttc ataaatattc acatcatcga
    22321 ttgtctgctg atcaacgatc ccgatcccga ttgccagggc tttttcttga acttgttgat
    22381 aaagaagttc tcgctttttc tctgataatt gtttggagtc attcagccct aatatgatct
    22441 catttttcgg caagataact gcagctgcca cgacaggtcc agctaatggt cctcttccta
    22501 cttcatcaat gccggcaatc cattggtgac cttgtgcgta cccttgcttt tcaaagcaaa
    22561 acatttcttc atatttttcc ttaattaatg cttccttttt caatcgtcgt tcaaaagaag
    22621 ccagtgcttg ctgcacgcct ttgcgtggat catttcttaa tgattctagt gtaggatcat
    22681 ctattctctg tatgcttttc aatcgttctt tgatactttg gatggattca gtcatcactt
    22741 ttttgctcca tttcttcgca acgatccagt gtgtatcgtc caagttttcc ttgacgaata
    22801 tcatgcacga ctaattcgct gccacgatca tagtcttctt tatacccacg ttttgctgta
    22861 atatccatca gtaattccgg tgccaatttt tcttcttgct cgattgataa accataacga
    22921 tcgctgattc ttcctgaata atatcgggca aaaaagtcta atccgtaaat cgctaaatca
    22981 tctaaatgga caagctggtc tttgatcgcg cctgtcagcg ctagtttttt gccgatttct
    23041 tcatcttcaa atttgggcca taaaatccct ggtgtgtcta acaattccaa ctcattacct
    23101 aaacgaagcc actgctgacc ttttgttacg ccaggcttat ttcctgtctg tgcaattttc
    23161 ttgcctacta gtcgattcat caacgtagat ttcccaacat ttggaatacc taagaccatt
    23221 gcccgaatag cgcgaggctt gatcccccga gcagcatctc ttgcccgttt ttctttcaat
    23281 gcttctttag ccgcaggtac tagaccttta attcctttac tttcttgtgc cgtgatagct
    23341 aatgcaagat ggccttgttt acgaaaatat tcttgccaca gctttgtctg ttgtggatct
    23401 gccagatccg ctttattcaa taaaacaagg cgaggttttt gctgaatgat ctgatctagc
    23461 attggattac gagaagataa aggtaatcgt gcgtctacca attcaaatac gatgtccaca
    23521 tatttcattt tttcagaaac ttctcgtcgg gcttttgcca tatgtcccgg aaaccattgg
    23581 atggtcattg ttctctccat tcctttcata ccggaatatt ccccggcttt acttgttttt
    23641 ttctttt
//
LOCUS       DACCVH010000037        23646 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.037, whole genome shotgun sequence.
ACCESSION   DACCVH010000037 DACCVH010000000
VERSION     DACCVH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.037"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(25..600)
                     /locus_tag="IVV98_001525"
     CDS             complement(25..600)
                     /locus_tag="IVV98_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7807191.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(605..1579)
                     /locus_tag="IVV98_001526"
     CDS             complement(605..1579)
                     /locus_tag="IVV98_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAP7807192.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1603..1647)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1862..2830
                     /locus_tag="IVV98_001527"
     CDS             1862..2830
                     /locus_tag="IVV98_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7807193.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2927..3220
                     /locus_tag="IVV98_001528"
     CDS             2927..3220
                     /locus_tag="IVV98_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP7807194.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3338..3574
                     /gene="secG"
                     /locus_tag="IVV98_001529"
     CDS             3338..3574
                     /gene="secG"
                     /locus_tag="IVV98_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP7807195.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3686..4432
                     /locus_tag="IVV98_001530"
     CDS             3686..4432
                     /locus_tag="IVV98_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7807196.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4435..6792
                     /gene="rnr"
                     /locus_tag="IVV98_001531"
     CDS             4435..6792
                     /gene="rnr"
                     /locus_tag="IVV98_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP7807197.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6814..7278
                     /gene="smpB"
                     /locus_tag="IVV98_001532"
     CDS             6814..7278
                     /gene="smpB"
                     /locus_tag="IVV98_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP7807198.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7580..8299
                     /gene="atpB"
                     /locus_tag="IVV98_001533"
     CDS             7580..8299
                     /gene="atpB"
                     /locus_tag="IVV98_001533"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP7807199.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8352..8567
                     /gene="atpE"
                     /locus_tag="IVV98_001534"
     CDS             8352..8567
                     /gene="atpE"
                     /locus_tag="IVV98_001534"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP7807200.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8658..9182
                     /gene="atpF"
                     /locus_tag="IVV98_001535"
     CDS             8658..9182
                     /gene="atpF"
                     /locus_tag="IVV98_001535"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP7807201.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9169..9711
                     /locus_tag="IVV98_001536"
     CDS             9169..9711
                     /locus_tag="IVV98_001536"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP7807202.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9734..11290
                     /locus_tag="IVV98_001537"
     CDS             9734..11290
                     /locus_tag="IVV98_001537"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP7807203.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11304..12206
                     /locus_tag="IVV98_001538"
     CDS             11304..12206
                     /locus_tag="IVV98_001538"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP7807204.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12229..13635
                     /gene="atpD"
                     /locus_tag="IVV98_001539"
     CDS             12229..13635
                     /gene="atpD"
                     /locus_tag="IVV98_001539"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP7807205.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13649..14071
                     /locus_tag="IVV98_001540"
     CDS             13649..14071
                     /locus_tag="IVV98_001540"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP7807206.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14540..14770
                     /locus_tag="IVV98_001541"
     CDS             14540..14770
                     /locus_tag="IVV98_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP7807207.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14867..16168
                     /gene="murA"
                     /locus_tag="IVV98_001542"
     CDS             14867..16168
                     /gene="murA"
                     /locus_tag="IVV98_001542"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP7807208.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16181..16357
                     /locus_tag="IVV98_001543"
     CDS             16181..16357
                     /locus_tag="IVV98_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP7807209.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16492..16788
                     /gene="yidD"
                     /locus_tag="IVV98_001544"
     CDS             16492..16788
                     /gene="yidD"
                     /locus_tag="IVV98_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP7807210.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16852..17319
                     /locus_tag="IVV98_001545"
     CDS             16852..17319
                     /locus_tag="IVV98_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807211.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17404..18288
                     /locus_tag="IVV98_001546"
     CDS             17404..18288
                     /locus_tag="IVV98_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7807212.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18405..18638
                     /locus_tag="IVV98_001547"
     CDS             18405..18638
                     /locus_tag="IVV98_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP7807213.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18726..18806
                     /locus_tag="IVV98_001548"
     tRNA            18726..18806
                     /locus_tag="IVV98_001548"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18760..18762,aa:Tyr,seq:gta)
     gene            18813..18884
                     /locus_tag="IVV98_001549"
     tRNA            18813..18884
                     /locus_tag="IVV98_001549"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18845..18847,aa:Gln,seq:ttg)
     gene            19400..20107
                     /locus_tag="IVV98_001550"
     CDS             19400..20107
                     /locus_tag="IVV98_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807214.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20166..20810)
                     /locus_tag="IVV98_001551"
     CDS             complement(20166..20810)
                     /locus_tag="IVV98_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP7807215.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20937..21224
                     /locus_tag="IVV98_001552"
     CDS             20937..21224
                     /locus_tag="IVV98_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807216.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21332..21652
                     /locus_tag="IVV98_001553"
     CDS             21332..21652
                     /locus_tag="IVV98_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807217.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21970..23046
                     /locus_tag="IVV98_001554"
     CDS             21970..23046
                     /locus_tag="IVV98_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7807218.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23043..23646
                     /locus_tag="IVV98_001555"
                     /pseudo
     CDS             23043..23646
                     /locus_tag="IVV98_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7813 a         4125 c         5092 g         6616 t
ORIGIN      
        1 ttttgctaat ccagctctgt ttattcagcc tatttttctt tttgaatata tcaagcgttg
       61 tggcaacata gtgatgacta atgaaacaac gacgatagac aacaaacgat caaggtagtc
      121 tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt aaacctaacc catgtaatag
      181 ctgaacgatc atactggatc ctgaggaggt gatcccgcca aataactgaa cggtaatgat
      241 cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg agtaataaca gtttcaagct
      301 gtttttatct ttgccgagat atcttggcaa aatcaatcca gcaagcaagc ctgtgagaat
      361 ttggattggc gaataataca gagaaaaaat atctgtagtc actccactta aaataccgct
      421 ggacaatcct gtcagcattc caggtacagg cccaagcaat gcaccagcaa aaatcgttcc
      481 gatagaatcg agatagattg gcaaacgaag ccataaagca atcgttcctc caatataatt
      541 gatcccaata cacaaagcca tcactgtaag tacgcgagtt gccattttgt ttttattcat
      601 tttgttagcc catctttaac ctttccaaat ctttcataat cgtttcttct tgtgcattta
      661 aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc ataattttac
      721 tgttagcagg tttctgccaa aattcataac gatcaaccaa tgtttgtcca cgacttattc
      781 cttgagtttc cacagcagtg aagcttttga aaccttcaca gatggcctcc tcgataaaat
      841 aagcaacagc taacggatca ttgatgacac atcctaaaat tctttcttgt ttccagtgga
      901 agtcaaaata aaaacgagtg atcgctttta gatactctcc ctcttcagga ttcatttgac
      961 agcagtattc gaggatagtc ggtgtcaaga cgatttctct tgtcacatct aacccaacca
     1021 tttctatcgt ttgtttgaga ttctcgaata cataagaagc tgcttcagga tcacaccagt
     1081 aattgtattc agcaactggc gaacagttac catggctttt gtaagttcca cccatcgaga
     1141 caaaacgttc catatgtttc ccaatatttg ggttgacttt caaagcagaa gcgatattgg
     1201 tcaaaggacc caaagcaatg actgatgtat ttgtcttttc tttgaaataa tcagccaaaa
     1261 aatcaacggc atggagaggt tctgcctgtt ttctcaagat catcgggaaa tttgtttccc
     1321 ctaaaccatc cataccatga gtgtcttgtg cactgatgaa aggttgcttc aaaggttttt
     1381 ccattccttg ataaacagga atgtctaaac gatcacagcg ttccaggcat ttcagcacat
     1441 tctgcgtacc tatatctgca gggacattcc cacaaactac ggtaatagca actacttcga
     1501 tatcagggga tttgacagct aatgataaag ctaaagtgtc gtcgatccct ggatcgcaat
     1561 caataattac ttttcgcatt atttccaatc tcctttcttt agagatactt agttttttat
     1621 tctgggaagt ttccgaacca gtccaagacg agcgtcttga ttataatgca cgaaattagt
     1681 atactggctt ttattgcgaa tgtaaatgct ctcttacaag taaatctatt gaggagaact
     1741 ttaagtaaat gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa taaagaatcc
     1801 tatggatcgg tacattggat aatagataga ttatagtttg gcagaaagcg gcgggtgtac
     1861 aatggttatt ttttatttca ttcttattct gataattata gggatcagtt accattttct
     1921 ttcttatttt tatgcaaaga aattagtaag agcgggagta cagagaggat atgactggta
     1981 tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag aaaaaaaacg
     2041 acaaaaatta gaagaagagt gtgaaagctt ttgggagcag ggaacaccca aaacaatcaa
     2101 aagttatgac gggttgaaac tagctggtca gatgttcatc catccaaata agcagaataa
     2161 atgggtcatt tgcgtacatg attaccgaag cacagggaaa agagacatgt ctcatatagg
     2221 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
     2281 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
     2341 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
     2401 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
     2461 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
     2521 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
     2581 ttactcctta aagcaagcat cagctacgag acagcttggc agcaatcatc tgcctttatt
     2641 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
     2701 tgctacggca ggggataaag cactgctgct tgttccggaa gcagaacact tggaagcatc
     2761 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
     2821 gatgaattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
     2881 tcaggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
     2941 atatggaaat caaagaagaa aaaatcgtct tgctttattc aatgatgaac aacaagagat
     3001 cggagaaatg acatggtcag atgcgggccc agacatcatg atcgttgacc atacatttgt
     3061 agatccagca tatcgtggtc aaaagttagc tgaaaagcta gtgtatactg gagtagaatt
     3121 agcaagacga gacgggaaaa agatcattcc tttatgccct tatgcaaaaa aagagtttga
     3181 aaagaaacca gaatatcaag acgtcttacg tcagtcataa gaataacagc tgaaagtttt
     3241 gaactttcag ctgttattcc atttatatag agttgtcacg gacttttatc tatgataaag
     3301 ttaaagagac gatatctttt gggaaggagg ctgcgatatg tataatttaa ttttgggaat
     3361 cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg atgcagccaa gcaagcaaaa
     3421 tagtgcagcg agtgcattta ccggcggtgc ggatcaacta ttcggcaaac aaaaagctcg
     3481 cggctttgaa gctgtcatgc agcgatcaac tgcagttatg ggagctatct ggatgatctt
     3541 attatttgtc ctagcatatt tatcttcgaa gtagttgaat aagcctctcg caaaacggcg
     3601 ggcggctttt tttattgcaa agagaacgct taagaagaag ttatgaaaga aactatggta
     3661 aaatgaggcg aaagaggtga gacgagtgag acaattacca aaaccccttt atgcaaaaca
     3721 tggaaagcga gcggttttgc tgcttcacgc ttactcagga agtccaaacg atgttcgaat
     3781 gctcgcacga tttttggaaa aagcagatta tacagtttat gcgccgcttt ttaaaggaca
     3841 cggaacaatg gagccatatg atatcttgca agaaaaagca gaaagctggt gggcagacac
     3901 taaaaaagcc atccattttt tacagtctga gcagttttct gatattgccg tattaggatt
     3961 atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga ttggcggcgg
     4021 ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact ttgaaaaata
     4081 cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg aaaaagcagt
     4141 tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg cagcaatcgt
     4201 agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg ggaaagatga
     4261 aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc agcgagtgac
     4321 acttcaatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa gacgcgaatt
     4381 agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat aaatatgaca
     4441 aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa acgcagtttt
     4501 tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt taaattacta
     4561 gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa aaaaggaaaa
     4621 gtgaaacttc ctttaaaacc aatcctgatc gaaggaacat ttcgagcaaa tgaacgagga
     4681 tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa agaagcgact
     4741 ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc aaatacagat
     4801 atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac tactcagtta
     4861 gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacagatct ttacggcgtt
     4921 gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc agagggagtt
     4981 cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga aaaagggtat
     5041 gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga ccctggcatg
     5101 gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga tgatgtattg
     5161 tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg acgtagagat
     5221 ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct agatgatgca
     5281 gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat tgcagatgtt
     5341 tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag agggacaagt
     5401 gtatatttga ctgatcgagt aattccgatg atcccgcaac gtttatcgaa tggtatctgt
     5461 tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat tgatccaaat
     5521 ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga acggatgacc
     5581 tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca acgctatgct
     5641 cagctcgtac ctatgttcca agaaatgggt gaattgcacc gaatccttga aacgatgcga
     5701 atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga aaatccttgt tgatgctgaa
     5761 ggacacccaa atgacatcca gctaagaagc agaggaattg gtgaacgctt gatcgaatct
     5821 ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa tctgccgttt
     5881 atttaccgaa tccatgaaca gccaaaagaa gaaaaaatgc agcgcttctt tgattttgct
     5941 tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa agatttacag
     6001 catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac tatgttgcta
     6061 agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg cttagcggca
     6121 gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat cgtccatcgt
     6181 ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg ggctgcggaa
     6241 cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga aacagaacgt
     6301 gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtgggaga agaattcgat
     6361 gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa tacagtagag
     6421 ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga aaatcattta
     6481 gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt gcgagtaaaa
     6541 gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc cgcagaagag
     6601 gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg cgaaggaaaa
     6661 caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag cgatagtaag
     6721 caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa aaagaagaaa
     6781 aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg aaaattaatt
     6841 gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga agcagggatg
     6901 gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct aaaagatgga
     6961 tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag tccttatgaa
     7021 caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt acacaaaaaa
     7081 caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt tcctttaaaa
     7141 gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg gaaaaaatct
     7201 tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga tcgaacatta
     7261 aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt ttgcttttac
     7321 ttaatgataa aatttgttag catttaatct gataaaacat gattatcata ggttttttct
     7381 tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga aataaaaaag
     7441 tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg ataccgtgtg
     7501 gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg tgaatttcgg
     7561 ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg gaccaatttg
     7621 gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt tcttcttagc
     7681 ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg cgatagaatg
     7741 ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag aattgagcaa
     7801 tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca acatcggttt
     7861 agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga cagcagaccc
     7921 gtttgttact ttaactttgg catttataat gatcttactt actcacttat tcggggtgaa
     7981 aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccctata gttttatgtt
     8041 tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac gtctttatgg
     8101 gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatgatga caagcttagg
     8161 ctggttctca ttaccattag caattccatt agagatggtc tggatcgcgt tctccttgtt
     8221 tattgggagc atccaagcat ttgtctttgt cactttgtca atggtttata tgagccataa
     8281 gattgaagta gaagaataat actcggttaa aaaacaaact actatttatc tattttagga
     8341 ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca gcaatcggag
     8401 ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct cgccaacctg
     8461 aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtt gaagctgttc
     8521 ctatcttagg ggtagttatc gccttgattc tagtttttgc cgtttaattg aatcagtatt
     8581 aaggcagaaa caacatcgtt tgttactgct tttttacatg gaaactagaa atactccaaa
     8641 gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc aatgcgatgt
     8701 taggtaatat catcgttgtc agcggctcat ttttgatact actggctctc ttgaagcact
     8761 ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc gccaatgatt
     8821 tagattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa cgcgaacaac
     8881 aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa gaaagtggag
     8941 aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt ctaaaaagca
     9001 aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta aaagacgacg
     9061 ttgcagaact ctctcttcaa atcgcggaaa aaatcttgaa caaagaatta tctccagaaa
     9121 tgcatgaatc attaatcaat caatacattg aaggtctagg ttcttcaaat gaaactagat
     9181 aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat cgattcaaat
     9241 caagcagaag aaatctatca agatctcgta agtttacgtc aaatctatga acaagtacct
     9301 ggattaggga atatgttaag tgatgttcgt ctagaacctc atgaaaaacg agaaatcatg
     9361 gacaagcttg tcagcggtta tgatgggatc gttaaaaact ttttagaagt tgtttatgag
     9421 tataaccgaa tggatgacct tttgttcatg atcgaagaat atgaacgtcg atatgatgaa
     9481 catcaagggt tactattggg aagtgtcaca acagcagtcc cactttcaga cgaacaacga
     9541 atacaattag aaaagaatgt tgcaaaaaca atggactatc aatcagttga attaaaacaa
     9601 atcgttgatt cttctattat tggtggcgcg attgttgaag ccaaccatcg agtaatcgac
     9661 ggaagcattc gcacgcaatt agaaaaaatg cgtaatcaat taaacagata gtacaaagag
     9721 gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta aagaacaaat
     9781 tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt atgtaggtga
     9841 cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc ttgaattttc
     9901 aaacggctca tacggaatgg cgcaaaactt agagtcaaat gatgtaggta tcattatcct
     9961 tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggta agatcatgga
    10021 agttccagtt ggagaggcct tgatcggtcg ggtagtcaat ccgctaggtc aaccaatcga
    10081 cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcgatgg caccaggtgt
    10141 tatgcaacgt aaatctgtta acgaaccaat gcaaacaggg ctaaaagcga tcgacgccct
    10201 tgtgccaatc ggacgcggac aacgtgaatt agtcatcggt gaccgtaaaa cagggaaaac
    10261 ttctattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct gtatctatgt
    10321 agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga aaaaatatgg
    10381 cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcac cattgcttta
    10441 tatcgcacca tatgctggta ctgcaatggg tgaagaattc atgtacaacg gtaaacatgt
    10501 attgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac tttccttgct
    10561 acttcgccgt ccaccaggtc gtgaagctta tcctggggat gttttctact tgcactcacg
    10621 tttattagaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa tgactgcctt
    10681 accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa acgttatttc
    10741 gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta ctcgtccagc
    10801 ggttgatgcc ggactatctg tatctcgtgt aggaggttct gcgcaaatca aagcaatgaa
    10861 aaaagttgct gggactttac gcctagactt agcaagttac cgtgaattag aagcatttac
    10921 acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg gacgccgtac
    10981 agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac aagtagtgat
    11041 tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta ttttagactt
    11101 cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg aaacaatccg
    11161 tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg aatataaaga
    11221 catgttctta gctacaaaag gaagtaattc ctctacagaa gataaattga aatccattca
    11281 aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag acacgtatcg
    11341 cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct gcttctaagt
    11401 tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa gtaagagaaa
    11461 tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat cctagagggg
    11521 atatcaatta caacagcatg ctgctcagcc gtcctgtgaa gaaaactggt tatatcgtca
    11581 tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa caaacgatgt
    11641 ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca attggcggaa
    11701 ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg cgcaatctat
    11761 ctgatcagcc aagctttgat gaagtccgca aaattgtaaa tatggcaaca actatgttcc
    11821 aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat tcgctaacta
    11881 gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa gaagcaacga
    11941 ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct cagttattgc
    12001 ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca gcagaacatg
    12061 ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc attgatgagc
    12121 tgacggtttc ttataaccgt gcaagacaag gggctattac ccaagaaatt accgaaattg
    12181 ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat gagttcaggc
    12241 aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga ccaatcctta
    12301 ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc aaaagttgtt
    12361 cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat ggaatcaaca
    12421 gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc tgttcctgta
    12481 ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga tttagaaaca
    12541 cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc ctttgacgaa
    12601 ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt gcttgcccca
    12661 tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa aaccgtactg
    12721 atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt atttaccggt
    12781 gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga ttcaggagtt
    12841 atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc acgtatgcgt
    12901 gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg tcaagatgta
    12961 ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt atcagccttg
    13021 ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga aatgggtcaa
    13081 ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca agcaatctat
    13141 gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca tttggatgcg
    13201 acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt agatccattg
    13261 gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta taaagtagca
    13321 acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat tgctatctta
    13381 ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg cagagtccaa
    13441 ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc aggttcatat
    13501 gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa atacgatgat
    13561 cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga aaaagcgaaa
    13621 acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa atgtggtaac
    13681 tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta cgacagctgg
    13741 tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga ttgatgaagt
    13801 tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta atggcggaat
    13861 catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac gtgaacgtga
    13921 tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa tcgaagaagc
    13981 aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc accgagcaat
    14041 caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta tccgtgttta
    14101 agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag aaggaattta
    14161 cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga agctacttct
    14221 ggaacaccgt atatcagagg ttgtgaaatc agcgttttgt cctgagtatt agagaaacaa
    14281 atggaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg tcagatgatt
    14341 gaacaccgtt tatttggaat aagggactgc gacaagactt ttgtctcagt cccttttttt
    14401 gcatattttt agcatttatt tcctaaaaaa tgtaagggga ttcctatatt tttaagtata
    14461 cttgtttttc cttttataca ttttatggta ttatcatttt attagttatt ataaaacaat
    14521 cgttagaaag gacgtcatta tgcaagtata cggaattgat gcggtgcttc gaatcgtgag
    14581 tcatttggcg tttatctact tagccttctg gtctttacgt tcgttacgca ttgaaacttt
    14641 tttcagacca atgcataata cgcaaattag aatggcaatc gtactttttt caattttttt
    14701 agggtacact gcaagtaatt ttttcttaga ggttatcgct ttatgccgaa atcttttcgt
    14761 tagcctgtaa attttaaaaa aaggtactat tttaaaagca aggatgttat aatagaaaag
    14821 attttgagta agtgtatgct cattggaatt ttttggaggg aacaacatgg aagagatcat
    14881 cgtaagaggt ggcaatcaat taaatggaac agtaagaatt gaaggagcta aaaatgctgt
    14941 tttgcctatt ttagctgcta gtttgttagc agaagaaggt attacgacat tagacaacgt
    15001 tccgattctt tctgatgtct tcactatgaa tcaagtgatt cgtcacttaa acgtagatgt
    15061 agattttgat gaacaaaaga atcaagtaac aatcgacgct tcaagacaat tagaaatcga
    15121 agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc gttgtgatgg gtccgctact
    15181 tgccagaaat ggacatgcaa aagtagctat gcctggtgga tgtgcgattg gtaaacgacc
    15241 aatcgatttg catttaaaag gatttcaagc tttaggagca aaaattattc aaaaaaacgg
    15301 ctatatcgaa gcaattgcgg atgaattgat cggtaacacg atttatttag atttccctag
    15361 tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa gcaaaaggaa caaccatcat
    15421 tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca aacattttga ataaaatggg
    15481 cgctcaagtc tatggagctg gtactgaaac aatgcgtatt gaaggcgtgg atcatttaca
    15541 tgcagtcaac cactcaatcg tacaagatcg tatcgaagca ggtaccttta tggttgctgc
    15601 tgcaatgaca caaggcaatg tgctgattgc agatgctatc tctgaacata accgcccatt
    15661 gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa gaagaaggcg gagtccgtgt
    15721 catcggacca aaacatatct tacctacaga tgtaaaaacg atgcctcatc ctggtttccc
    15781 tacagatatg caagctcaaa tgacagctat ccaattagtt gcagaaggta caagtgtggt
    15841 gactgaaaca gtgtttgaaa atcgtttcca acatttagaa gagatgcgcc gtatgaacgc
    15901 tcatgtcaaa atcgacggaa atgtagcaat catggatgga aaccatgaat tgcaaggtgc
    15961 agaagtatat gcaacagact tgcgggcagc agcagcatta gttttagctg gcttgaaagc
    16021 aaatggaatc acacgtgtgc gtaacttgaa ttatctagac cgtggatatt ataatttcca
    16081 tatcaaacta cagcaattag gtgcagacgt cgaacgtgta gacatggatc aaacttctgc
    16141 tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga atgagtaacc aacgatatat
    16201 cttattaact ttgataaaga ttttagtggt gatcttattg cttatccttc tttttgtggc
    16261 cggaacgatg atcggatatg gtgtcatcgg tggcggcaat ccatttaaag tattccagcc
    16321 aagtttgtgg attcatattc gagacttttt tcattgataa ataagaatca cagtggttct
    16381 agtcgatatg aagtgagcca tgaagcagaa catgataaaa gaaaacagaa gggaacgttg
    16441 acgttagtcg cgatcccttt ttttagtaaa agaaaagaag gaatctaatt gatgaagaag
    16501 atattgattt atttagttag aggatatcag cgctttattt cgcctgcatt tccacctagc
    16561 tgccgttatt acccaacctg ttccaattat atgataaaag caattcaaac ccatggtgcg
    16621 ctaaaaggga cggtaatggg gactgcacgg atcttacgct gtcatccttt tgtcaaaggc
    16681 ggtatcgatt atgtaccatt gacattccga ttaacgcgaa ataagaaaga taaaaaagaa
    16741 ccagattata aaaaggttgt gaaaaatacg ggtagcactg agcgataaag aaaaagagga
    16801 aatttattgt caaagtaaca actccgcaac tacttatatg ggggacaaaa aatgatcgaa
    16861 gaactaaaca agaaagattt accatggtcc ttgttattag atgcagatcc tgataaagaa
    16921 aaagttcaag tatatgtttc cagagggagt ggctggatat ggaaagaaaa agaaaaaaca
    16981 ataggtgtac tgatctatgt ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta
    17041 accccaacgt atcaaggaaa ggggattggc ggaaaattac ttgagacagc ttttcagaag
    17101 ctttcacagc tagcttcaaa ccaaactcgg atcattatac gtactggcac tactagtagc
    17161 gctgcgttac acctctatca aaaaatgggc tatgtggaga ttggtcgagt caaagactat
    17221 tttatccatc attactctga gcccattttt gaaaatggag atcaattaag ggatcaagtg
    17281 attttagcaa ttcacttacc taaaaatagc tttaactaat aaactttcaa ttcgagaaaa
    17341 tgctttcaaa tgctaaatag atacattaca atagctttag caaacaaaaa ggagaatatt
    17401 tttatgggaa tattagtttt tgattttggt ggatcggctg tcaaatatgg ttgttgggat
    17461 ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg aatcttggga agaaatgaaa
    17521 acgcaattat ttcaagttta taaaaaaata ctcgtttctt ttgaagtcga aggaattgga
    17581 atcagctctc ctggagtagt gaataatgag aaacaggtga ttgagggaat cagtgcgatt
    17641 ccttatattc atggatttaa tattttccga gatttggaaa ctctgtttca actcccagta
    17701 acgattgaaa atgacgccaa ctgtgccgga atggctgaat tttatgaagg tgctgcccgt
    17761 gattatcaag atgttgcttt tgttgtggca ggaactggga ttggcggggc gttgttcacg
    17821 aaaggacaaa taaataaagg ggcacatctt tacggtggag aatttgggtt gatgttctta
    17881 gatggcgata agacattcag taaacttggt acagcggtac agatggcttg gcgttattgt
    17941 gaacgcaaag gtctcgataa aaatgcttat accggaaaag atgtctttga attagcagaa
    18001 actggagatg caatagcaaa agaagaagtt gagagttttt atacgtatct tacaaaggga
    18061 ttattcagta ttcaattttc gtttgatcca gaagtgatcg tattaggcgg cggggtttct
    18121 gcaaaagaag ggctcattga tgagatcaaa agccgaatga agaagctgac agaacaattc
    18181 gatctgcatg atttcgaacc gcagatttta ttatgtgagt acagaaacga tgctaatctt
    18241 ataggtgcag cagcaaacta tctcgctgta cgtcaaggag agaattaaga gctttagaga
    18301 aggtgcagct tgcataaaag aagagaatga aatgaatagg agatttttac ctaaggaatg
    18361 ttttatttgc tgcagtatga taaaatatct gagaggtgaa aatgatgtca aaaaaaaata
    18421 aagatattga agtgcgtata gaagaagtga aaaaagatat caaaggtaag aattatgaag
    18481 tcactcagtt atttataggg aaaaaaatga ttggtgagat cttagcctat gggccaaaag
    18541 aatatgaaat tttctttggt gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga
    18601 tagaaacagt gattcgacac tggaatctgc acgaataaaa aaatatcaaa aaaactttca
    18661 ataaagggtt gcaaaaatct ggaaaattag gtattataac taagtcaggt tgatacaaac
    18721 ctttcggagg agtagcgaag tggctaaacg cgacggactg taaatccgtt ccttagggtt
    18781 cagtggttcg aatccactct cctccatttc attggggtat agccaagcgg taaggcaagg
    18841 gactttgact ccctcatgcg ttggttcgaa tccagctacc ccagtatacc acaatcgtaa
    18901 gctctcgtta gttcgagagc tctttttttt tgctttgcta ccttgttcct tgaagattct
    18961 gctgaattaa gatagagtta agttaactac aagaattgga gggatccaca tgaaatggaa
    19021 agaaaaagta gacgaagcag ctgaaaagtt atatgatttg gtcaaatcag aaaaatacaa
    19081 tattgaagtg aatattccga aaaaaggcgg aaaagcggtc caggtaaaat caaaacgccc
    19141 aacgaatcat acaaaaaaat ggatggctaa aaaccgctaa taataacaaa agatccataa
    19201 gtcggcattt tcatcgattt tagggtcttt tgttattttc taggttgaac atatctaaaa
    19261 aattgtttct gacaatagga gtagggagaa cgatgtgtgt ctaaatcctc tgttgatgga
    19321 tagaaacctt tatctttttc agttgtgaat caggtatata ccagttataa tagaagaaac
    19381 gaaaggacgg gtgtacgtta tgtcgaatca attacctgta tatatacaga ttcatgacca
    19441 attaaaaaat gaaatcgaac aaggtatatg gaaagtcgga gaccgtcttc cttcagaaag
    19501 agaattagca gtgaaattca atgtcagccg tatgacgttg agacaagcaa ttcaaaactt
    19561 ggcagatgaa ggaatcttag aaagaaagat cggttcgggt acgtatgttg cgcgagaaaa
    19621 agtacaagaa aaaatgtctg gtgcaacaag ttttacagaa attatggaat cacaaaatcg
    19681 agtaccgtct agtcggacaa tctcttattt cttgacttcg ccaagctcaa gtgaaatgga
    19741 aaaactaaac ttgagtaaag atgacacgat cttgcgaatg gaacgtattc gtttcgcaga
    19801 tgatgtccct atttgttttg aagttgccag tgttccacaa aagctgatcg atggctacag
    19861 caaagcagag attactgaat cgttgtatcg cacgctagaa gaaaaaggcg ggaaaaagat
    19921 cggtccagcg aatcaaacga ttactgctgt gttggcttct gagaaaattg ctgactattt
    19981 agaggtaaaa cgaagagatg cagttcttcg tttgcgccag atttcttatt ttgaagacgg
    20041 tacgccgttt gagtatgtgc gtacgcaata cgtaggaaat cgttttgagt tttatttgga
    20101 aaaataaaaa acaggtgatc cctgattcct tattagaaat aaaagagaat cagaatcacc
    20161 tgtttttata tatgatcagt tatcagttgc tcgtgataag aaacagaacc ctcttcaaat
    20221 tggacttgtc cgttcagcag ctcaatgatg gattctttaa agtggttagc acttttttca
    20281 tctacagcac agatgacgct aacttgatca gtatattgga tttcttttat aaaaaaatgt
    20341 tggagttcaa gataattctg taattttcct agttgcggat acgtgatcat cacagagatc
    20401 tcctgttgca aggtaccttc tacgattcca atgtcagaca atgcttgaga gaccgcatga
    20461 gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc ctccaaaata tcgagtgact
    20521 actgcagcta cattgatcag ttgatttttt ttgaggactt ccaacatcgg tacgcccgcc
    20581 gttccacttg gttctccatc atcgctgctt cgctggattt catttttttc tccaatgatg
    20641 aaggcgctgc agttatggtt cgctttccaa tgttcttttt ttatttcttg aatgaaattt
    20701 tttgcttggt cctctgattc tattcgtcta agagaacaga taaagcgtga ttttttgatc
    20761 tcaatctcac tttgtccatt ttcttttatt gtacgatagc gctcgatcat cttgtcacct
    20821 ctttttttca ttttctttat tcagtataaa taaagttcta ggttgtttca acactgtaac
    20881 ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag gcaggtggat ctggggatgc
    20941 aggaacgaat gaaaaagtac gatgcaatta cgcattattt gaagaacaat ggcggctctc
    21001 aagtaacgtt gacctttacc caatttgacg aactgctgtt tcccagtaac ggacttccca
    21061 aaacagcaag ggaaagtaca gattggtggg caaatgatta taaacaccct gaaaaaggtg
    21121 cctatggctg gataaatgca ggctatgaag tagttgtcat caatttggac aaagaatatg
    21181 tcgtgttcaa taaattagtg aaatctagtt ggctatttga ttaaataaac cgcgtttaga
    21241 aaacgttgac aaatttcttt ctttttatat aataaagtaa cagacgcgaa gaaaacgttt
    21301 gcgtagtttg ttttaaaaag gagagaaaaa tatggctaaa aaaacaatca tgcttgtatg
    21361 ttcggctggt atgagcacaa gtttactagt aacaaaaatg caaaaagctg ctgaagcaaa
    21421 aggaatcgac tctgatattt tcgctgtgtc cgcttctgac gcagataaca atcttgcaaa
    21481 taaagacgtg gatgtgttgt tattaggccc acaagttcgc tttatgaaag ctgattttga
    21541 gaaacgtctg gaaccaaaag gcattccttt agatgtcatc aatatggctg attatggtat
    21601 gatgaatggc gaaaaagtgt tagatcaagc aatcgcgctc ataggtgaat aaatagaaca
    21661 gtataactat cgaacaagcg atccaaaaaa tagatcgctt gttttttcgt atattttttt
    21721 agggcgaata atatgaatca tttttggggt agaaggcttc tgacgagaga tattaaagca
    21781 atagactgtg aggaggtaaa tttaccaaat tatgagaaga tcgcagcagt ggaacgtttg
    21841 ggcaactgga ttctttgtca tcgctgtgga atgaggacgt ccgtcattgt tggacagctt
    21901 gcagattacg gttatttttg tacacattgt ctatatttag ggtgatgcga cactcaacaa
    21961 gatttatatt tgtttgatca gcctgaagca aaacctcgag aagtcgtctt tttttggaca
    22021 ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa tactttgcca ttcagaaaaa
    22081 agacatcatc ttatttgggc tgtaacaggt gcagggaaaa cagagatgct ttatcctatt
    22141 ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt gtacaccgcg agtcgatgtt
    22201 tgtaatgaat tgtttttacg ctatcgttat gtttttccag aagaaaaaat cacgttgctc
    22261 catgggaata cagcaacggc ttataccttt acttcttttg ttatctgtac gattcatcag
    22321 ctataccgtt tttatcggtc ctttgattta atagtgatcg atgagatcga tgcgtttcct
    22381 tataacgggg atgctgggct agctcacgct gtgcaaacag caatcagatc aaacggccga
    22441 ttcatctact taagtgccac gcctgatgag aagttactaa aggaaatcaa gcagacattt
    22501 gagctccaca aacttgcctt gcgctttcat cggcgcttgc ttcctgaacc cgtgcttgtt
    22561 ttcatgaata attggcgaca aaaatgtgga aacaaaaaga aaatcaactc tttggtgcgg
    22621 atcattcagc aactaatcaa agaaaaccgt atccttttat tttgtccaag tattacgatg
    22681 atgcatcgtt taaaaatcac actgcaagaa gcttttccag aatatgagat aacagatgtt
    22741 tcttcacaag acgatcaacg ggcaaagaaa gttcagaaaa tgcgagaagc aatatacgag
    22801 atactgttaa ccacaatgat cctagaaaga ggagtcacat ttgaaagaat ctctgtcatc
    22861 gttttaggag cagatcatcc agtttttact aaatcctctt tggtgcaaat cgcaggaaga
    22921 gctgatcgta aaggtcctta tacgaacagt cgagtctatt ttttctatga agaaaaaact
    22981 tcagctattc gaaaagcctg tcaggaaatc aaagaaatga acgaagaagg gaagcagatg
    23041 ctgtgagatg tagttgctgc ggtaaagaca tcattcaaaa tttaacattc agcgagatca
    23101 tcggagtgtc gaaatctaga cttcctcaga catgttcagt ttgccgcgca caattccatt
    23161 tattagaagc aaaaggttgt gcaggttgtc aaaaaccaat ccatttgaaa tacgaggaga
    23221 cgaaaaagaa agcaaatact agtttcgttt actgcaacga ctgtcaagaa tggaagaaga
    23281 aatatcctgc atatgatttt caacaccgcg ccttttttac gtacgatgaa aagatgcagg
    23341 cttggatcaa tcggtacaag tttatgggag atatccgatt agcagggact tttgcatata
    23401 aatggactca gataaaaaaa agattacccg gcatatattt attgtccaat acctttatct
    23461 gaaaaaaggt ggctagaaag aggattcaat caagtaagcg agatgttgaa agcagcaaaa
    23521 attccttttc agatgctgct caaaagagag caacatctgc ttgctcaagc aaaaaacacg
    23581 cgaaaggaaa gattggagat gcctcagcct tttgagcttg ccgtacctct ttctaagata
    23641 caacat
//
LOCUS       DACCVH010000038        23227 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.038, whole genome shotgun sequence.
ACCESSION   DACCVH010000038 DACCVH010000000
VERSION     DACCVH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.038"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            438..992
                     /locus_tag="IVV98_001556"
     CDS             438..992
                     /locus_tag="IVV98_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7807219.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1165..1638)
                     /locus_tag="IVV98_001557"
     CDS             complement(1165..1638)
                     /locus_tag="IVV98_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7807220.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1650..2186
                     /locus_tag="IVV98_001558"
     CDS             1650..2186
                     /locus_tag="IVV98_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7807221.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2226..2597
                     /locus_tag="IVV98_001559"
     CDS             2226..2597
                     /locus_tag="IVV98_001559"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7807222.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2881..4152
                     /locus_tag="IVV98_001560"
     CDS             2881..4152
                     /locus_tag="IVV98_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP7807223.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4397..5422
                     /locus_tag="IVV98_001561"
     CDS             4397..5422
                     /locus_tag="IVV98_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7807224.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5716..6825
                     /locus_tag="IVV98_001562"
     CDS             5716..6825
                     /locus_tag="IVV98_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7807225.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6908..7804
                     /locus_tag="IVV98_001563"
                     /pseudo
     CDS             6908..7804
                     /locus_tag="IVV98_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7820..8644
                     /locus_tag="IVV98_001564"
     CDS             7820..8644
                     /locus_tag="IVV98_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807226.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8676..9986
                     /locus_tag="IVV98_001565"
     CDS             8676..9986
                     /locus_tag="IVV98_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAP7807227.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10134..11393
                     /locus_tag="IVV98_001566"
     CDS             10134..11393
                     /locus_tag="IVV98_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7807228.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11403..12275
                     /locus_tag="IVV98_001567"
     CDS             11403..12275
                     /locus_tag="IVV98_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807229.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12287..13117
                     /locus_tag="IVV98_001568"
     CDS             12287..13117
                     /locus_tag="IVV98_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807230.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13157..15340
                     /locus_tag="IVV98_001569"
     CDS             13157..15340
                     /locus_tag="IVV98_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP7807231.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15401..16621
                     /locus_tag="IVV98_001570"
     CDS             15401..16621
                     /locus_tag="IVV98_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAP7807232.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16618..18078
                     /gene="gtfA"
                     /locus_tag="IVV98_001571"
     CDS             16618..18078
                     /gene="gtfA"
                     /locus_tag="IVV98_001571"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAP7807233.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18155..19261
                     /locus_tag="IVV98_001572"
                     /pseudo
     CDS             18155..19261
                     /locus_tag="IVV98_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19583..19792
                     /locus_tag="IVV98_001573"
     CDS             19583..19792
                     /locus_tag="IVV98_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP7807234.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19785..19934
                     /locus_tag="IVV98_001574"
     CDS             19785..19934
                     /locus_tag="IVV98_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAP7807235.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19969..20753
                     /locus_tag="IVV98_001575"
                     /pseudo
     CDS             19969..20753
                     /locus_tag="IVV98_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="IVV98_001576"
     CDS             complement(21037..22122)
                     /gene="xerS"
                     /locus_tag="IVV98_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP7807236.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22456..22689
                     /locus_tag="IVV98_001577"
     CDS             22456..22689
                     /locus_tag="IVV98_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP7807237.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22686..23093
                     /locus_tag="IVV98_001578"
     CDS             22686..23093
                     /locus_tag="IVV98_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP7807238.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
BASE COUNT         7953 a         3467 c         4433 g         7374 t
ORIGIN      
        1 aattattgac gctcccgaca aaattatgat cttgcgtaaa gttataaaat attaataaaa
       61 atattttatt aatgaaaagc ttggtagcac ggttattcat atgctaattt atttcacttt
      121 atagtaaggg gagttcttag tatattgttc aaacttaaat ttcatataat ttaattatgt
      181 aaattagcta ttctaagaac ttctacggat aactgcccgt ctaaaattta aataagagct
      241 tagaatcttc atataagtaa ggttaatttt tttgtacaaa aaagtcggaa tattctgagt
      301 tactgaaatg atataaaatc ataaactaaa tcccttgatt ttattgactt tcaaaagttt
      361 atatatataa gttaatgatt atggtaaaat atatacataa tcattaactc agaatatttt
      421 taagaaggga aacaatagtg agctataatg tacaaccgtt aaggacaaat gaagagatac
      481 aagattttca gttttggcta agaagaacaa gtaatccgga aagagatagt tttttatttt
      541 tgtttggaat caataatggg ttacgtatgt cagatattat aggattaaaa gttggagata
      601 tacgaggcaa aagtaagcct attattgttg aacataaaac aggtaagcga aaaccgattt
      661 ttatagataa tttgagagaa gaaattttat tatatactga aggtaaagaa gaaaatgatt
      721 ggttatttcc gagtcggcaa caaggtcgac atataacaag ggatcgtgtc tatcagatat
      781 atgcagatat agcagaaaaa ttaggacgag atgatatagg aacacataca ttaagaaaaa
      841 cttttgggta tcactactac aagaaaacta gagacattgc taccttaatg tttattttta
      901 atcatagctc gcaagcaatt acaaaaaggt acattggtat aactgaagat gaaataggag
      961 catcacttcg tggatttaaa ctaggtgtat aatttaaaaa tttttataaa cagtaaagac
     1021 aaagattaaa agctattttt atctagaacg attttatttc ataaagttcg cggaataaaa
     1081 gctggggtta ctggtacttg gtataggttc gtgttatata aactaagtaa ttaaataaca
     1141 tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc aatacggtct caaaaacgca
     1201 aacgctgcgg aataagaaaa atactgataa ctcaacgttt agcagactat ctaataggga
     1261 tagtctgctt ttttcgtttt tgaccatact tttgaccttc tgcaaacttc cttgcttttc
     1321 ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt tcctctgtct gctttttcgc
     1381 gatatgggtg tatatatcat ccatagtggt tttaatatct gtatgtccaa gtcgaacata
     1441 cacttctttg acagacgcac cagattcaaa gagcagacta caatgggtat gacgaaaacc
     1501 atgaagtgtg atatgtttta agttattctc tttaatgatg attttcaaat tgtgatttac
     1561 atagtctaaa taaaggggct tattttcttc tgatgaaaac aaaagttgtt caccatcttt
     1621 tataggtttg attctcattt ttagatatta tgcccgcacg tattcatcac atttctattg
     1681 tgaatcgctt tattcgaccg acatttgact tttatcataa tatactcggt ttaaaattac
     1741 taatgaaaac aattaatcaa gacgatcata ccatgtatca cctgtttttt tcagataatc
     1801 accaccgtgt gggaactgaa ctgacttttt ttgaagtaca agaagggaac aaccagtttt
     1861 ttggaaccaa tacgattgaa cgaacgatac taaaagttcc ttccgaagca tcattgcatt
     1921 tttgggaaat atattttgaa acacaaggcg tttgccatta tggaatcgaa tcattttctg
     1981 gacgacctat cttacgtttt gaagggccag atgcaacacg attagcttta gttcccttac
     2041 gcgaatttga agatattgat gattatttcc cgtatgtcac agaccagatc cctacagagc
     2101 atgccatttt aggaattgat gccattcaac tacgcgtaca atattccgat gcgactgaac
     2161 gagagttatt gtcggtaggc tggtagcaca aagaatacgt cagtttcttt tcgggtcatc
     2221 aacgagtgac aatcttagaa aatcaagaca ctcagttcta tcaagaagtt cagattattc
     2281 aagatcgtga gaatccagtt gccattgaag ggattggtag cgtccatcat gttgcgtttg
     2341 gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca attacaagag cgcaatttta
     2401 taaattcagg aataaaagat cgtgaatttt ttgtatcact ttattatcgt gacccaaatc
     2461 aattattgat tgaaattgct acaggggaag gaaacctaga tgcaaaagcg tatgaaaatc
     2521 aaagtccacg ctttgaagaa attcctttat ttttaccgca gtacttaaat ttcattcgtg
     2581 aacaagtgga gcaataatta gctaatcaaa tccatgacga agagtaagag gttgactcat
     2641 aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa agaatgttga tttgatgcgg
     2701 ttcctatttt tataaactat cattttcgac taataaaact acttatgagt cagcctctct
     2761 ttttttcttg atttttatac ctctttctag gtaaactaaa catctgccaa aaataccgtg
     2821 tctcattgaa acattctcaa ctatttcaaa ataaagggga gtaccaaatg aacgagtata
     2881 ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca gtctcaaaat tcccaaaaat
     2941 aaaattagta tttttaccag cgtatctggt tcaggaaaat catcgattgt ttttgatact
     3001 attacccaag aagctggtcg tcaactgaat gacacctatg atagttttac ccgtttattt
     3061 ttacctaaat acagtcgtcc agaggttgat gagattgata atctttctac ggcgattgtg
     3121 gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt tagggacgat tactaacatc
     3181 aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac ctagtttagg atatgcaaat
     3241 gcttattcat ttaatgatcc tagtggaatg tgttctgtct gtcagggaat cggtaagacg
     3301 attgcatttt taataggatt gctttatttt tcggctattg ataatgctga ttttgtattt
     3361 tctgatccat ttaccgcaga agttttgtct ggaattgagg aacaggcaaa gaatcatggt
     3421 tattttgtat tggtgcataa tgttaattca gcagaagatg ttaaaactat tcagagaaat
     3481 tggcgttttg aggggttcat tgttgttggt gtacgtgtaa aagaattttt ggaattaaat
     3541 aacgtttttg atggtcctgt tgtttatatt gatacgcatc tttcaaaaga gacattaaga
     3601 gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa atgattacca agctagtaca
     3661 ttggcagtgg aacatttgat tcattatggt catgagaaaa tagcgtttct ttcttttgac
     3721 tacattgtag gtgaaccaag tgttattcaa gaacgacatc aagcttatat cgatacatta
     3781 aagaaatatc atttaacctt taaatcgcat tggatatata acaactctga atttgagcga
     3841 atttatcaag aattagctga atttactgca attgttgtta ctggagatta tttagcggct
     3901 aaattagtaa aatttttaaa aaataagaat aaacgagtga tggaacaatt atcgattatt
     3961 ggatttgatg atattacttt tgcagaatta atggatcctg cgttgacaac aatacgacta
     4021 aatccaggta acaagggggc gattgctttt caccaactga ttggactggc caaacaagaa
     4081 gaaataaaaa atcaagtact actattagag ggagaattga tttctcgaga ctctgttcac
     4141 aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa caataaaata tccgaacgat
     4201 agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa ttcactagaa ttagcattat
     4261 ttactctaaa ttgttcggat attttttctt gtttttaatt atgattacag tgcctatttt
     4321 taacgaaatt tgcttatttt caaaatgtat gattatatgt tagtaaacac tttcaaatat
     4381 gaaaagagga gctattatgg taggaattag ggatgttgca aaacgggcgg gtgtgtccat
     4441 tgcaacagta tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg atgaaaccaa
     4501 acgaaagatt gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc ccgttgcaaa
     4561 aaatttaaca aatattgcat taataacgac agtttctgaa gtagatgagt tggaagatcc
     4621 ctattttcga acgattcgca gagggattca agtcgaagca gaacaaagca aagtcaattt
     4681 gaagaaaatt attcgtttgt cagaaacacc gttggagcaa gacgatttgc taaaatgtca
     4741 aggtgtgttg attattgggc aggtgctatc ttctgtgatt gaagaagtat cagcaattaa
     4801 ttcgaatgtc gtagtgattg atgaccctag tattgaagct gaagtagatg cagtttatac
     4861 tgatttaaca aaagcaacga atcagcattt agatcgattg tataaaaaag gacaccgaaa
     4921 cattgcgttt atcggaggag gacgtgttcg tttagatagc caaggaaata aacacgtgtc
     4981 agatgatgat tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag gattagaaaa
     5041 atatagtcaa atttatttag aaggctggac cacacttgac ggaatgcagg cagcagattt
     5101 acttttgaaa aaacatgcta aagataagtt gccgactgct atcatggtag gaaatgatcc
     5161 tattgctgtg ggggtttatc gttcacttca aaaaaatggt ctacatattc cagaagatat
     5221 ttcgattgtg agttttgata atattgaagt tgctgaattt ttaacacctg cattaaatac
     5281 ggtgaatgtg aatacagaag aaattggaaa actagcagtt cgcatggtta atgaacgaat
     5341 aaaagaagtt agaaatgttt cgatcaaagt gattgtttct aataatatta ttgttagaga
     5401 aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa aagggtgttt acttttttgt
     5461 ttactaatat ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt atggtgttgt
     5521 taacaaaaag aaaacgcatt caaaacagga ggaattaaga tgaaacattt caaaaaaata
     5581 gctttaacag ggatagctgt tttaactggg acattactcg cagcatgtgg tgggggagat
     5641 agtaattcta aagacgggca agtaacttta agctatgcga gttgagatac tgaccaagct
     5701 ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa atcctgatat caaagtagaa
     5761 atggagacaa cgccttggga tcaatattgg gttaaattag aagctgcaac aacgggaggt
     5821 aatatgccag atgtagtaac catgcactct agcgaatcct ataaatatat gtcacagaat
     5881 gctttgatgg gacttgatga tgttatcaaa gaaaatgata ttgacatggg aaactttact
     5941 gaaggaattg ctgatttcta tacgcttgaa gacgaactat acgcaatccc taaagatgct
     6001 tctgtagtgg ggctatggta caacaaagaa ttatttgata atgcaggtgt cgattatcca
     6061 gatgaaacat ggacatggga aacactcaga caagctgcaa ttgatttaac agatgaatca
     6121 aaaggcatct atggttttgc atcacatatt ggaacagaga ctggctactg gccatttatt
     6181 tatcaaaatg ggggagaagt atttgccgat gacaatacaa aatcaggttt gaatacccca
     6241 gaagcacaag aagctttagc tttttatcga gatattgcac ttgttgatca tgcttcacca
     6301 acaattacag aattacaaga tcctgataag ttaagtcgtt ttcaatcagg tagattagca
     6361 atgatgattg aaggaaactg gtttgcaccg ggatttttga aaaatgacta tctagttgaa
     6421 aatgttgctt ctgccgtgtt acctaaggga aaagttaatg caacaattac aaatggactt
     6481 ggttgggctg ccagtgcgag tacaaaatac ccagaagaag tgaaaaaact aatggcattt
     6541 ttagctagtg aggacgccaa taaaatccaa gcggaaacgg gggcatcaat cccagcacta
     6601 aaaggctttg aagacgagtg ggctgcttct tcagatacaa ttgatttgag tgcttttgga
     6661 aaaatgttgg agtatggagt ccctcgtcca tacaataaag atggattacg agctgaacaa
     6721 gcagaagttc aaattattaa ccgtattctg tctggtgaag taactgttga agatggaacc
     6781 gctcaaattg aaaaagaagt caatgcgata ttgagcggaa attaaattag ttaattatac
     6841 aatatacagg cgaaaggatt ctatttcgtc tgtatattaa tggatgaata ccaaaaaggg
     6901 ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga tatggggcta
     6961 tatttttatt tttccaacgg cattaggatt aattttatta aatatatggc cagcaattca
     7021 aacagcaatt ttaagttttc aaaaaacggt agggttcggt gatactgaat gggtcggatt
     7081 aagaaattac caaaaaatgt ttgcagacgg tgaagttttt cagtctttat taaacacatt
     7141 aatttatgca gtggtttcga tacctagtat tgttgtatta tccttgttgg tggcagtttt
     7201 aatgaataga aaagttaaag gattgtcgat ttatcggaca atttattttc taccagtcgt
     7261 tgctgcacca tccgcagtcg caatgatttg gcgctggatg ttcaataatg attatggact
     7321 gattaataac atgttggcta aaataggtct cgatggacca gcatggttaa cggatccatc
     7381 gattgcgatt tattctatta tcattgtagg agtttggagt gctattggtt ataacatggt
     7441 gttattacta gccggcttat aagaaattcc taaagattat tatgaagcag cggaaattga
     7501 tggtgctagt ccaatccagc agtttttcaa cattacgtta ccattagtta caccaacatt
     7561 attttttgta gttgtaacaa cagttatcaa tgctttccaa gtatttgatg ttatttttat
     7621 gatgattact cctaatagta ccgccatgtt taaatcacaa tcattagcct atttattcta
     7681 taaacattca tttattttaa atgacaaggg atatggttcg gcaatcgtta tgttcctttt
     7741 agtgattata ttaattatta ctgcaattca aatgaagttg cagaaaaagt gggtaaacta
     7801 ttaaggaggc tatcaaatta tgaaaaataa atttttttca aatgcgccaa tccatatcat
     7861 gcttatttta ggtggtattg caatggcatt accttttatt tggatgattt taacttcagg
     7921 gaaaacgttg gttgaatcta cccaaattcc acctacaatt ttccctgaga aatttcagct
     7981 aagtaactat caacaagtac ttgatttatt accattcatg gctttttata tcaatacatt
     8041 tttaatggtt gttggacgag tgattggctc ggttttattt tcagcaatgg ctgcatatgc
     8101 ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc agcttagtac ttattcaaat
     8161 gatgattccc ggttccattt ttattactcc acagtattta ttagcacaaa aattgggtat
     8221 tttaaataca attccagcat taatattacc aggggtagtt agtgcgtttg gtacgttttt
     8281 attaagacaa tttttcttag gtttacctga tgaattggag gaagcggcct atttagaagg
     8341 tgccaatatt tggacgatct ttttcaaaat tatgttgccg cttgctaaat caggattggt
     8401 tgcacttgga atattcacag cgttgtttgc atttaaagat ttaatgtggc cattgattgt
     8461 caatacttca attgataaga tgcctttagc tccgggatta gcaaacttac aaggacaata
     8521 tgccacgaac ttcccacaat taatggcagg ttcgttatta gcaatttggc caatagttgt
     8581 gatattcatc gttttccaaa gaaaattcat tgaaggaatt gctacaacag gtagtaaatt
     8641 ataaaactat taattagtga ttggagagta agtacatgac aaaaattaca tttattggtg
     8701 caggaagtac tatttttgca aaaaacgtat taggcgatgc gatgttaact ccaagtctac
     8761 aagatgcaca tattgcattg tacgatattg atgaaaaacg actaaaagaa tcaaatttaa
     8821 tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc tgatattgtt tcttattatg
     8881 atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa tgctattcaa gtgggtggtt
     8941 ataaaccttc aacagtgatt gattttgata ttcctaaaaa atatgggttg cgacaaacta
     9001 ttggtgacac catggggatt ggtgggattt ttagaaccct acggacacta ccagtaatgt
     9061 tagactttgc taaagaaatg gaagaagttt gtccaaatgc ttggttattg aactatacaa
     9121 atccgatggc gatgttaacc atgggtgttt taaaagcgac gagtattaag actgttggtt
     9181 tatgtcatag cgttcaagta tgcgtaccag aattgtttga gcatttagga atagccgatc
     9241 aatatgactt aaatgacttt caatggaaaa ttgcaggcat taatcatatg gcattcttgt
     9301 tggaaattac aaaaaatggg gaagatttct atccaacaat tcgtcagtta gctgcagaaa
     9361 aaccaaatcc acatccagat tctgtacgtt ttgaattgtt gaaacgtttt ggttactata
     9421 ttacagaatc aagtgaacac aatgcagaat accatccata ctttattaaa tcaaaatacc
     9481 cagaattgat tgacgaatta gggattccgt tggatgaata cttacgtcgt tgtgaacaac
     9541 aaattaatga ttgggaaagc atgcgagagg acattgtaaa taatggggag ttaacacata
     9601 cgagaagccg tgaatatgct tcatatatca tggattctat tacgacagga actccgtcag
     9661 tgattgcagg aaatgtctta aataaaggct taatcacaaa cttaccgaca gatgtttgtg
     9721 tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc ggtgaattgc
     9781 caacacaatt agctgcttta aatcggacga atatcaatgt tcaagaactg acagtagaag
     9841 ccgctttaac actagataaa tcaaaaattt atcaagcagc gtatttagat ccacatctat
     9901 catctgaatt gtctttaaca gatatcaaaa atttagtgga tgatttaatc gaagcacatg
     9961 gggactattt acctgaatat aattaaaaag aagctgaaag agtaaggaat tttcaattcc
    10021 ttactctttt cttagttaaa tttagtaaaa atattgacaa aacacttagt aaacagttac
    10081 attagtgtta acaaaaagaa aacgcattca aattgtataa ggaggagcat aaaatgaagt
    10141 ggtctaaaaa aattatttta gcttgtatag cactaggagc aacgatctct ttgactgctt
    10201 gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat agagtttttt aatcaaaaaa
    10261 aagaaatgac tcaaacgatt caggagattg ctaaagattt tgaagcaaaa aaccctgata
    10321 ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt aattaaaaca cgtatgcttg
    10381 caggcgatgt accagatgtc attaatcttt atcctcaaag tatagaattg aaagaatggg
    10441 cgaaagctgg ttatttagag gacttaaccg aagaaccgta tttagagaat atcaaaaatg
    10501 gatatgcaca acgttttgct attgaggatc gtgtatatag cataccatta accgctaatg
    10561 tctatggttt ttactataac aaaactgctt ttgaggaaat ggggattcaa gcaccagaaa
    10621 cttgggcaga atttgaaaaa atagtagctg agattaaaga tcaaaacaaa gtaccgtttg
    10681 cgattgcagg agcagaaggc tggactttaa atggttatca ccaactagct atagcgactg
    10741 ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt ctcagaagtt aatggaatta
    10801 atgctgaaag caaagaaatg caaaaagatt ttaatcgatt agatttgtta agagaaccaa
    10861 aagctttgca aaacaactgg caaggtgccg gttataacga tacagtagtt acttttacaa
    10921 aaggtgatgc gttgattatg ccgaatggtt catgggcaat gccgatgatt cattcacaaa
    10981 atccagattt tgaagtagga acttttcctt ttccagcaga tgaagcaggt caaagtctaa
    11041 cgattggcgc aggagaccta gccttatcag tttctgcaac ttctcaacat aaagaagaag
    11101 ccaaacgttt tgtagaatat atgacaacac ctgaagcgat gcagaaatat tatgatgtag
    11161 atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac tcaggattca ccattaagtg
    11221 gtttaactga acttgctttt actgatcgtc atttagtttg gttagccaaa gattggaata
    11281 gtgaaaatga tttttatacc ttaacaacaa attatttaca caatggcaat caaaaagcca
    11341 tgattaacgc attaaatgct ttctttaatc caatgaaagc tgacggaagg taggaaaata
    11401 aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat catttttgta gcaattccaa
    11461 ttattttgca gatgattttt ttctactttc caatggttca aggtgctttt tacagtttaa
    11521 ctaattggac tggtctgact tataattttg attttgtggg tttgaacaat tataagattc
    11581 ttttttctga tccgaagttt atcaaatcga ttggcttcac tttaattgtg acgctttgca
    11641 tgattgctgg acaaattggt tttggtattt tgattgcgcg ggcgttgaac gcaaatatta
    11701 aagggaaaac attctttaga gcatggttct tttttccagc ggtcttatcg ggcgtggttg
    11761 tttctttagt atttaaacaa atttttaact atggtttacc aaaaattggt agtatgttag
    11821 gcattgaatt tttacaaacc agtcttttag gaacaacatg gggagcgatt tttgcagtaa
    11881 tttttgtttt actttggcaa ggaattgcca tgccagtcat cattttctta gcgggttttc
    11941 aaagtattcc acaagaaatt attgaagctg ctagaatgga tggggcgaat gataagcaaa
    12001 ttttttggaa tattgaaatc acctacttat taccaagtat ttcaatggta tttattatgg
    12061 cattaaaagg tggcttaaca gcatttgatc aaatttttgc tttaactggt ggtggaccaa
    12121 gcgatgccac aacatctttg gggttacttg tttataatta tgcttttaaa aacaatcagt
    12181 ttggttatgc gaatgctatt gctttagtct tatttatctt aattgggatt gtttcactgg
    12241 cacaattaaa attatcgaaa aaatttgaaa tctaggaggt ttcccaatga aaacatcaaa
    12301 agaaaaaaat atttctaaat acttgctttt attattaggg ggcttcatga ttttagttcc
    12361 cttagtttca acgctattcg gttcatttaa aacaacaccc gatattatga ataatttctt
    12421 tcgttttcct aatccagcga ctttggaaaa tttccgaaga ttgttagcgg atggaattgg
    12481 tcattacttt tggaattcgg caatcatcac aatcattgca gtagttgctg tgacagcaat
    12541 tattcctatg gctgcttatt cactagcaag aaaaatgact cgtgggaaag catacggatt
    12601 gatgtattta tttttaattt taggaatttt tgttcctttc caagtaatta tgattccgat
    12661 taccgttatg atgagtaaaa ttggtttagc aaatatgtgg ggattaatct tactctatct
    12721 cacttatgcc gtaccacaga cactattttt atatgttggt tttattaaac taaatgtgcc
    12781 tatcagtctg gatgaggctg ctgaaattga tggggctagt cactttacaa cttatttcaa
    12841 aattgttttc ccaatgttaa aaccaatgca tgcgacgact attattctta atgctctatg
    12901 gttttggaat gatttcatgc taccattatt aattttaaat cgtgattcta atatgtggac
    12961 actaccattg tttcaatata attatacggg acaatatttt aacgactatg gtccaagttt
    13021 tgcttcctat acagtaggaa ttgtcacgat tacactagtt tatcttgctt tccaaagaag
    13081 tattatagct ggaatgagca atggagcagt gaaataacca ataaattatt ctcattataa
    13141 aggagttcat aaacttatga ttatatttga caatcacaca caaacatttc atttacaaaa
    13201 taaaaaaatt agctatctat taggaatcga agaaaataat tatttaacgc atctttattt
    13261 tggaaaaaag attacgcact attctggtgg gtatcgctac ccccgaacag atcgttcctt
    13321 ctcacccaac aatgcaaatg cgcaagatcg tttattatct ttagacacat taccattaga
    13381 atttccagga tatggacatg gtgattttag agaaccggcg cataatatta aattaggaaa
    13441 cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa attcaaaaag gaaagcccag
    13501 cttagcggga ttgccagcct tatatacgga agatgatgat gaagctgaaa cgctgattat
    13561 tcaattgaaa gacgcgatta gtggattgac tttacagttg ttctacacaa tttatcaaaa
    13621 tcacagtgta attattcgtt ctacgcaatt agtaaataat agtgatgaaa cagtggagat
    13681 taaccgctta gctagtcaat caattgattt tccaaatcgt ccactcgagt taattcattt
    13741 aaatggtacc tgggcaagag aacgtcaaat gactagagaa aaaattcata cagggataaa
    13801 agtattagat agtaaacgcg gatcaagcag ccatcaacaa aatccgtttg ttgctttagt
    13861 agatgccaaa acagatgaat ttcaaggaga ggcatatgga tttaatttag tttatagcgg
    13921 taatcacgaa acggtgattc aaaaagatcc atttgaccaa acacgggtca ttatgggaat
    13981 taattcattt aattttggtt ggcaactaaa aactggcgac tcatttcaaa cgccagaagt
    14041 cgtgatggtt tatagtaatg aaggtctgaa tacgttatca cagacgtatc atgaattgta
    14101 taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa cgtcccacgt taatcaacaa
    14161 ctgggaagca acgtattttg attttaacga agaaaaaatc atgaatattg tcgatgatgc
    14221 gaagaacttg ggcattgaaa tgtttgtttt agatgatggt tggtttggcg gtcgtgaaaa
    14281 tgacttcact tcattaggtg attgggttga aacagaaggc aaacttgctt gtggtttgga
    14341 aaatttagcc aagcaagtgc atgataacgg gatgaaattt gggatttggt ttgaaccgga
    14401 aatgatttct gaagatagtg aactatttcg agcacatcca gattgggcat tgggtattcc
    14461 aggtcgtgac cgctcaatta gtcgaaatca atatgttctt gatttttcaa gacaagatgt
    14521 tcgtgataat atctatcaac aaatgacggc gatttttgat cgtgtaccga ttgattatgt
    14581 gaagtgggat atgaatcgaa atatgacaga agtctattct gtcttgttgg actcaacgat
    14641 gcaaggtgaa gtggctcatc gttatatgtt agggttatat gaatttttag aaaagttaac
    14701 aacgaattat ccaactattt tatttgaaag ttgttcgggt ggaggcggtc gttttgatgc
    14761 aggtttcttg tattacatgc cacaaacttg gacgagcgac aataccgatg ccgtggctcg
    14821 tctgaaaatt caatatggaa ccagcttagt gtatccaatt tcaagtatgg gtgcgcatgt
    14881 ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt ttaactattc gtggcaatgc
    14941 tgcgatggct ggtgtttttg gttatgagct agatctaacg caattaactt ctgaagaaaa
    15001 agcagaaatt aaagaacaag ttgcctttta taaaaagcat cgccaacttt tgcaatatgg
    15061 aactttttat cgcttggaaa gtccgtttga aggcaatgat actgcatgga tgtttgtctc
    15121 aaaagaccaa acagaagcca tggtctttta tttccgagta ttagcagaag ctgcgcatcc
    15181 attagtcaca ttgaaattag caggattagc agaagaagca acttatcaaa tggaagatgt
    15241 aacatttgct ggcgatgaat tgatgaatct cggtttttat attgactcag aactacatgg
    15301 tgattatgcg acacaacgct tttatttgaa acagatatag tagcttgaat ttacaatata
    15361 agtgcaacac caaaagagac tcattccaaa cgaagaaaat atgttttatt tacacgcatt
    15421 tactaaaaag cagcctgatt tgaattggga aaatgaagaa gtacgtgaag aaatctatgc
    15481 aatgattaac tattggttag ataaaggact aggcggattt agaatcgatg cgatattaaa
    15541 catcaaaaaa aaactagagt atggcatctt tgaatctgat ggagaagatg ggttagcctt
    15601 cattgggccc tggattctta atcagtcggg cattgaagtg tggttaaaag aaatgagaga
    15661 gcggacattt aaaccacata atagtatgac ggtagcagaa gccgatgttc ctaatgaacg
    15721 tttagatgaa tatattggtg aagatggcta ttattcgatg gtttttgatt ttagttatac
    15781 ggatattgat gtacctgaaa ctggtgaatg gtttaaagat agccaatgga catggacgga
    15841 tatgcgtacc aatattttta cgaatcaatt agttacgcaa gataaaggtt ggggcgcctt
    15901 atatttagaa aaccacgatc aaccacgttc aattaataaa tatattccag aagaatggat
    15961 caatgattat agtaaaaaaa tgttggcgac gctttttatg ttactaagag gtaccccttt
    16021 tatttatcaa ggacaagaac taggaatgac caacatagaa atggcatcat tagaagattt
    16081 tgatgatgta gctacgcatt ctcagtataa acgggcatta gaatatggat tggcaccaga
    16141 gcaagcattg aaagctgtca ataaacgaag tcgggataat tctcgcacac ctatgcaatg
    16201 gaatacgcaa aaaaatgcca gattctcaac ttctgataat gtatggttaa aagtaaatcc
    16261 taattatcca gaactcaatg cagaagctca gttaaccaat caacagtcgg tattcaatta
    16321 ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac aaagacgtgc taatctacgg
    16381 acaatttcta ccagtgaaag ataaaaatga acatattttg ctttatgaac gccaattaga
    16441 agataaaatc gtattagtta tcttaaacgt tacagcaaca gaacaagaat attatgtaga
    16501 tgaacagtac caacaagtat taatcaataa ttatgaagat gttttattag atcaaagtcg
    16561 aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct aattatggag gacaattatg
    16621 aaaattaaaa acgaagcaat gctcatcacc tatgcagata gtttaggaaa aaacatgggc
    16681 gaattaaaac aagtcttaga caaacattta caaggtgtta ttggtggtgt acatctgttg
    16741 cctttttttc catcgacagg tgatcgaggc tttgcgccga gtgattatac gacagttgat
    16801 ccagctcttg gaacatggga agatgtggaa gcattaggtg aagattatta tttgatgttt
    16861 gattttatga ttaatcacat ttctcgtgaa tcaaaatttt tccaagattt caaaaaaaac
    16921 catgagcagt caccatacaa agaaatgttt atccgtattc atgaattttt cccagaaaat
    16981 cgaccaacac aagaagatat tgatttaatc tacaagcgta aagacaaagc gccgtttcaa
    17041 acggtagaat ttgcggatgg tacgacagaa gaggtttgga atacctttgg ggaagaacaa
    17101 attgatttag atgtgaccaa agaagttgtg aaagaattta ttcgagaaac catcaaagat
    17161 atggcgaacc atggctgttc tttaattcga ttagatgcgt ttgcttatgc gattaaaaaa
    17221 ttagatacca atgatttctt cgtggaacca gatatttggg aacttttaga cgaagtgcgt
    17281 caagaagcag cgaaatatga cgtcgaatta ttaccagaaa tccatgagca ttattccatt
    17341 caaatgaaaa ttgccaatca tgattattat atctatgact tcgccttgcc aatggtcact
    17401 ctgtattcac tttatagtgg aaaatcagaa cgtttagcca attggttgaa aatgagtccg
    17461 atgaagcagt ttacaacatt ggatacgcat gatggaattg gtgttgtgga cgctcgtgat
    17521 ttattaacag atgaagaatt ggattacacc tctgaggaat tgtataaagt cggggcgaat
    17581 gtgaagaagg tctattcaag tgccaattac aataatttag atatttatca aattaacagc
    17641 acctattata gtgcattagg cgataatgac cgtagctatc tgttagcacg tgcgattcaa
    17701 gtatttgcgc cagggattcc acaaatttat tacgttgggt tattagcagg aaaaaatgat
    17761 attgaactgt tggaagcaac gaaagaaggg cgtaatatta atcgtcatta ctatgattta
    17821 gccgaaattg aagaagaagt gcaacggcca gtgattcaac aattatttgc acttttaaaa
    17881 tttagaaatg aatctgcggc gtttgatttg gatggaacga ttgaagtagc aacgccatca
    17941 gaatcagaaa tagtgattac acgtaaaaat aaaaacggta gtgatagtgc aacattaacg
    18001 gctaacttgg atacgaaaga atttatcatt gagtctaaag atataaaaat tttcactagt
    18061 gttgcattaa aattttaacc tattccatag aacaaaaaat cctttatact agcacttgga
    18121 tgacttatcc aagaccaata aaaaggactc atacatggat aagtataaaa caaatacagc
    18181 atttaataaa tggttttctg ccataaaatt aggaaaactt tctgtcaact cccaaaaatg
    18241 tatttttgat tacaattcgt atcgtaaaaa actgtctttt gaagctgtgc tcaagctctt
    18301 tctctacgca gttaatgaag aaaaagaaag tttgcgtgat ttgagtacag ctcttatcga
    18361 ccgatcgctc caactagaaa ccgatgtgtc atcgattagt catacccaat tgtctcgagc
    18421 atttaatgca cttgaaccta aagtgttaga agaaattttt caacaactgt tagaaaaagt
    18481 tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat ctgattgatt ccagtacgtt
    18541 ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt caaacaaaat caggtgtcaa
    18601 gttacactta aactattgtt atatggacga tactacgatg tatccaactg attttacctt
    18661 aacaaatgcc catgaacatg atctcaatca actaccagta ttggtgaatc aaccagaggc
    18721 aacttacgtg tttgatcgtg ggtattagga ctttgaaaag atggatcaga tgcattggga
    18781 tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa gttcacgtga tagatactct
    18841 ggaaacatcg ccagaaacag aaattctacg agacgagctg gttcgtttag gatctaaaac
    18901 ctatctaacc gccaatttcc gactagtcac tgttcaagat aagaacggac gtgtgtttca
    18961 atttatcacc aatcgaatgg acgtctcttc aaaagaaatc tctgatatgt atcacgctcg
    19021 ttggcaaatc gaattgtttt tcaagcacat caaacaacac atgaccatta aaaccttctt
    19081 ttctcaaagt gaaaaaggcg tgcagaatca attgatttta acgatgattt ccgctctcct
    19141 cacgtttctc atcaaattgg agacgaaaac ggaaaaatca gtgttccaaa tcaaacgatt
    19201 ctttcgttat ttactgtttc agccctttga atgttgtcta gaaaaattaa ttcccacatg
    19261 agaaaaaaga aatttggctc gttacttttg gttttcagtt gaataacaga taaaaaattt
    19321 tctggaaaaa gtcatcctct gcgtcagcac agtttttttt gacttatttt cagaggaaat
    19381 agttttcaga atattctaaa atgttttatg caacactagt gatatttttt agaattagat
    19441 ttctaatgtg cattttttga gtattaagga gcaagtatac aaagatttat aaagctgatt
    19501 aaatttgaat aaaaatatgc aggaacgcta ctatttttag tagtgttctt ttttatattt
    19561 gaataaaaaa tgtggtggtt aaatggtggt tataacaaaa aatgaattaa tgaaattagg
    19621 ttatgggaag tatcagtctg agagaatcat acgacaggca aaagcaatta tggcttcaaa
    19681 aagctatacc tattacgaaa atagaagatt aggactagta cctgttgaat ctgtagaaga
    19741 agttttaggt atgaagatag aggtagagga ggattttcag aatcatggtt aattttaaaa
    19801 aagataaaaa tgggaaatat cattttactg ctagtttggg attcgacaaa cgaacaggga
    19861 aaagagtaca aaaaaacgta gaggggttaa aacagttaaa gaagaaaaaa agcgtatacc
    19921 gaacttgttt ctaattatgg aaaagaagca gaaacttctc aaagtactat gttgtttgag
    19981 gagttttttt ataaattatt cctaccttat tatcaaggga aagtagaaga aagaacatat
    20041 aaaaatcggt tatctacaat caaaaaaact tttcttattt ctttaaaatg gagttaagag
    20101 aaatacgtcc aattgacatt caaaagtggc aaaataattt attgagcaaa tataaaaatt
    20161 cttatgtaag aaacatgtat gggatttttc agatgtcatt agatcgagca gttgttttgg
    20221 gactacttga aaaaaatcct gcaaaagtta ttggaaatgt gaagaaaagg aaaactacag
    20281 ttgatttttg gacaaaagaa gaatttacaa aagttatttc aactttttat attgatgatt
    20341 tgtaccaaca ttttggtttt atttgtatgt ggttactttt tatgaccgtt atgcgtttgg
    20401 gagaagccac tgcattaact tggaaagata ttgattttga aaataaaaac ttgcgtgtga
    20461 ataaaacact ctattataag agagccaaaa cctatgagtt tgtagaaccc gaaacggctt
    20521 ctagtattcg tacaatcgaa ctagacgaca atacaattac ctttttaaaa gcttggaagg
    20581 agcgtcaagt ttcaatagga ggcatgtcgt ttgtactttc ttataatgga acacctactc
    20641 agaaatatac aatccgtcat attatgagaa gacatgcaac gatcgttggt gttcatataa
    20701 tccgcataca cggattaagg catagtcatg cttctttgct tatatcacaa taaaaagatg
    20761 cacttcgaat taaagaaagg ttaaaacatg ctgatgtaca aacgacttta ggaacttatg
    20821 gtcatttgta tctaaattca ttgagagaga taacaaatga tcccacagat tatatccaaa
    20881 ctaatttttc taaaatcaaa ccgacaccta tttacgataa taaaaaataa atgataaaca
    20941 aaagtaggat cacaccaaaa gaaacacact agaaaaacta taatacaggc ttttctagcg
    21001 tgttgtttct tatttccgcc tatttataca ttatactcat aaagcattta atgcatcgat
    21061 cgtagccgca ttgtctatat gggtatataa agttgttgta ttggtacttg aatgtcccaa
    21121 ttgttgggca gttaatacca atgaatttgt ctgttggtag agtctagtag ctaatgtatg
    21181 acgcagtttg tgagggctga cttgaattct aaagcctttt gaatattttg ctaccatccg
    21241 ttcgattgca ataccggata tacgcttggc ttctccttgg taaattgcta gaaataaagc
    21301 tttttcgttt tctgttactt tatatcgttc tttccgaata gctagataat tagctaaata
    21361 ttccattgcg aatgctgcta tattgacagc atctctttta tttccttttc tagttactac
    21421 cacattattc ttatctaaag ataggtcatc taaattaata tttataacct cggagagtct
    21481 caatccagat cctaaaatca gtgcattgat cgccaggtct ctttctacat ctcgttgata
    21541 atagatcaaa gctcgtttac tcaaagtatt tttatattca ttggcaatat aatctagata
    21601 attttgtgta tccttatcta gaaataattt tttctcaatg gcattggcac gtgcagctaa
    21661 cgtagtttta tctgtgatgg ttgctacttg atccatagga ttattgtcta agtatggttt
    21721 tcctagagga ttattggaac ttttcgaaag atatttaaat agaaccttta atgccgtgat
    21781 atttctattg atagtagaag tagatagacc taagttatta ttatctttga gcttagtttt
    21841 tgttgtctct ttttttacat tttcttttgt gcgacgtttc aaatgagatt tgtacaagtt
    21901 taggtcatag gcagttaact gtcttatcga ggtgatagaa gtatcaggaa cgatagactc
    21961 actcagaagc cattcataaa agagcttata attttttaga tattctaaag tggttcgagg
    22021 tgattgatct ttatcctcac gatcttgaac aaaatctttt atataatcgg gcatatgaag
    22081 tatgattgta tctatttttt gatatatttc tgtatttttc atgtcattca tcctttcaat
    22141 aagtagggga gaagagtatc tctataattg gactatacca attatagaat gttttgtcaa
    22201 ttggtatgct ctaaaattta ttaatttgtt tcaaaaaaag catataaaca ggtatacgtt
    22261 taataattta aaataaatgg tatacataaa tagggaagga aatagaaggg agcaatctaa
    22321 attttttgaa ttttcttaat taattatata gaaagaacaa tctttctata gagttagaca
    22381 tgagagggac tatgcttgat ttaaaatcaa caagcgtata tactgtatat acaaagaaaa
    22441 aggagggaga agactatggc aattaaagaa agaaaattta gggaagtggg gaactcagta
    22501 gtattaacta tttcaaagga gtttcttaaa gaaaatgggt taaatcccgg agatacggtt
    22561 tttttagatg aagaaaaact tcgagcggca attacaaaaa aacaagcctt atctgatgaa
    22621 attgatttag caatatctca agcattaact gaatatgata ctacttttag agagcttgtc
    22681 gataaatgag tattcattac ctagaagcca aagatattat aaaaatgaat gtaatccaaa
    22741 taaaaaaata ctctcctaat gaaccccttg gtgtaaagga tgcgaatgct ttagaaatgt
    22801 gtgtagggca acttcgagcc tcagcttttg gtgaagaggt ttatccttcg atttatgaaa
    22861 aagcagctat cctacttata caattgataa agaaacatcc ttttcacaat gcaaataaac
    22921 gtactgcttt cttagctact tttgtctttt tgaaaatcaa tggacagctt ttagctattg
    22981 atcaaaaaga tgctgtaaat ttagcggtat atattgctac gtatgataag gatttcgatc
    23041 aactaaaata tgaagtgatc aacactataa agacacatac gcagcccatt taaggagtta
    23101 ctgtatgtgt ctttataggg ttattagctg ctatagcgaa ataattgaag taaattacaa
    23161 atagctataa ttcaaatcca actatataga aaacgtaaat tttctatata gttggattaa
    23221 gataacg
//
LOCUS       DACCVH010000039        23141 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.039, whole genome shotgun sequence.
ACCESSION   DACCVH010000039 DACCVH010000000
VERSION     DACCVH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.039"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..576)
                     /locus_tag="IVV98_001579"
     CDS             complement(<1..576)
                     /locus_tag="IVV98_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7807239.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(653..1183)
                     /locus_tag="IVV98_001580"
     CDS             complement(653..1183)
                     /locus_tag="IVV98_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP7807240.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1187..2047)
                     /gene="rlmB"
                     /locus_tag="IVV98_001581"
     CDS             complement(1187..2047)
                     /gene="rlmB"
                     /locus_tag="IVV98_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP7807241.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2040..2435)
                     /locus_tag="IVV98_001582"
     CDS             complement(2040..2435)
                     /locus_tag="IVV98_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP7807242.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2432..3844)
                     /locus_tag="IVV98_001583"
     CDS             complement(2432..3844)
                     /locus_tag="IVV98_001583"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP7807243.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3841..4377)
                     /gene="cysE"
                     /locus_tag="IVV98_001584"
     CDS             complement(3841..4377)
                     /gene="cysE"
                     /locus_tag="IVV98_001584"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP7807244.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(4699..6159)
                     /locus_tag="IVV98_001585"
     CDS             complement(4699..6159)
                     /locus_tag="IVV98_001585"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP7807245.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6329..7486)
                     /locus_tag="IVV98_001586"
     CDS             complement(6329..7486)
                     /locus_tag="IVV98_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP7807246.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7520..8890)
                     /gene="radA"
                     /locus_tag="IVV98_001587"
     CDS             complement(7520..8890)
                     /gene="radA"
                     /locus_tag="IVV98_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP7807247.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(8953..9480)
                     /locus_tag="IVV98_001588"
     CDS             complement(8953..9480)
                     /locus_tag="IVV98_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP7807248.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9710..10516
                     /gene="proB"
                     /locus_tag="IVV98_001589"
     CDS             9710..10516
                     /gene="proB"
                     /locus_tag="IVV98_001589"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP7807249.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10513..11760
                     /locus_tag="IVV98_001590"
     CDS             10513..11760
                     /locus_tag="IVV98_001590"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP7807250.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11836..12180
                     /locus_tag="IVV98_001591"
     CDS             11836..12180
                     /locus_tag="IVV98_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807251.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12297..12623)
                     /locus_tag="IVV98_001592"
     CDS             complement(12297..12623)
                     /locus_tag="IVV98_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807252.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13238..14440)
                     /locus_tag="IVV98_001593"
     CDS             complement(13238..14440)
                     /locus_tag="IVV98_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807253.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14557..15072
                     /locus_tag="IVV98_001594"
     CDS             14557..15072
                     /locus_tag="IVV98_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7807254.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15271..15717)
                     /locus_tag="IVV98_001595"
     CDS             complement(15271..15717)
                     /locus_tag="IVV98_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP7807255.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15764..17242)
                     /gene="msr"
                     /locus_tag="IVV98_001596"
     CDS             complement(15764..17242)
                     /gene="msr"
                     /locus_tag="IVV98_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP7807256.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17596..18225)
                     /locus_tag="IVV98_001597"
     CDS             complement(17596..18225)
                     /locus_tag="IVV98_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7807257.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18209..18673)
                     /locus_tag="IVV98_001598"
     CDS             complement(18209..18673)
                     /locus_tag="IVV98_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7807258.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19160..20428)
                     /locus_tag="IVV98_001599"
     CDS             complement(19160..20428)
                     /locus_tag="IVV98_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP7807259.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20659..21396)
                     /locus_tag="IVV98_001600"
     CDS             complement(20659..21396)
                     /locus_tag="IVV98_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7807260.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21463..22032)
                     /locus_tag="IVV98_001601"
     CDS             complement(21463..22032)
                     /locus_tag="IVV98_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP7807261.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22160..23032
                     /locus_tag="IVV98_001602"
     CDS             22160..23032
                     /locus_tag="IVV98_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7807262.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
BASE COUNT         6492 a         4945 c         4195 g         7509 t
ORIGIN      
        1 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
       61 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
      121 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
      181 tgcttctttt aataaaagat gctgaattgc taaaggttct tgcaatgtga tctctgctaa
      241 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
      301 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taacgctttt
      361 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
      421 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
      481 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
      541 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
      601 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
      661 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
      721 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
      781 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
      841 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
      901 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
      961 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
     1021 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
     1081 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
     1141 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
     1201 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
     1261 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
     1321 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
     1381 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
     1441 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
     1501 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
     1561 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
     1621 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
     1681 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
     1741 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
     1801 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
     1861 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
     1921 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
     1981 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
     2041 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
     2101 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
     2161 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
     2221 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
     2281 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
     2341 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
     2401 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
     2461 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
     2521 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
     2581 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
     2641 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
     2701 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
     2761 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
     2821 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
     2881 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
     2941 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
     3001 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
     3061 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
     3121 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
     3181 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
     3241 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
     3301 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
     3361 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
     3421 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
     3481 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggttcg acattcaacg
     3541 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
     3601 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
     3661 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
     3721 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
     3781 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
     3841 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
     3901 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
     3961 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
     4021 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
     4081 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
     4141 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
     4201 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
     4261 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
     4321 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
     4381 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
     4441 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
     4501 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
     4561 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
     4621 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
     4681 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
     4741 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
     4801 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
     4861 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
     4921 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
     4981 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
     5041 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
     5101 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
     5161 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
     5221 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
     5281 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
     5341 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
     5401 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
     5461 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
     5521 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
     5581 cataccatcg cgtttttgga tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
     5641 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
     5701 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
     5761 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
     5821 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
     5881 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
     5941 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
     6001 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
     6061 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
     6121 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
     6181 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
     6241 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
     6301 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
     6361 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
     6421 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
     6481 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
     6541 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
     6601 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
     6661 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
     6721 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
     6781 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
     6841 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
     6901 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
     6961 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
     7021 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
     7081 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
     7141 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
     7201 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
     7261 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
     7321 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
     7381 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
     7441 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
     7501 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
     7561 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
     7621 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
     7681 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
     7741 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
     7801 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
     7861 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
     7921 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
     7981 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
     8041 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
     8101 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
     8161 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
     8221 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
     8281 cggttttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
     8341 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
     8401 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
     8461 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
     8521 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
     8581 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
     8641 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
     8701 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
     8761 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
     8821 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
     8881 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
     8941 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
     9001 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
     9061 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
     9121 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
     9181 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
     9241 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
     9301 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
     9361 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
     9421 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
     9481 cggttttcct ccctaaataa actactccta ttctaacata tccgaggctg taaaagactt
     9541 tctttacaaa ttcttcaaga aattctgcta tcttaaagta aaccattaat tcgttctttt
     9601 tccaaacgac tgcaagttgt acaaaaaaac tattttttac atgactttac tcgtcaaaac
     9661 aagtagaata gaacgaaatt aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga
     9721 aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca agtacattga tttatcccaa
     9781 tggaaatatc aatcttgcgg caatcgatca gttagctttt gtcctttctg atcttagaaa
     9841 tcggggaaag gaagtgatct tagtctcatc aggagctgta ggcgttggta tgcataaatt
     9901 acatttgtca gaacgtccga ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca
     9961 agccgaactg atgaatatct ataatcaaag attcagtgta tataatcaac agacggcaca
    10021 gatcctcgtg acaagagacg tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac
    10081 attggaacag cttttgatta tggacacgat ccctatcgtg aacgaaaacg atactgtagc
    10141 agtggatgaa ttagatcatc tgacaaaatt tggcgataat gatcagctgt cagccatcat
    10201 ggcaaaactt gtcgcggcag accttttgat cgtcctttct gatatcgacg ggttttattc
    10261 agataatccg actacaaatc ccgaggctca gatgtatcgc tatatcgata aaatcgatga
    10321 aaagattctg gcacaagcag gtggtgctgg tagcacattt ggaacaggcg gtatgcagag
    10381 taaattaaaa gccgcttcta ggatatttga agcaaacagc gcaatgattt tagcaaatgg
    10441 aaaaaatccg gcaattattt ttgatattct tgcaggaaaa gaagtaggta ctttatttaa
    10501 ggaggacttg aaatgactga cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa
    10561 caactagcac ttatgcctac aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc
    10621 atcaaaaaga atcaacaagc gatcattgaa gcaaatcata aagacttaga aaaagcagtc
    10681 gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc tgacacctga gcgaatcaat
    10741 gccatggcta cagagatcga aaaaattgct tcgttagacg atcctattgg aaaagtagat
    10801 gagatgtgga cgaacaccga cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg
    10861 atcggcatca tttacgaatc tcgtccaaat gtcacgacag atgcagctag tctagcattc
    10921 aaatcaggga atgccgttat ccttcgcggt ggcaaagaag cattcttctc gaatcaatta
    10981 ttagtccaat tattgcagca agtactggtc agtgctggcg aatctcctta tgccatccag
    11041 tttgtcgatg atacttctca tgaaactgca ggacagttga tgcgattgac agaatactta
    11101 gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg
    11161 gtacctatca ttgaaacagg tacaggaaat aatcacgtat atatcgataa agaagcacag
    11221 ttatctatgg cagtgaacat catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac
    11281 gcggcagaaa cattgctgat ccattctgag atcgcacctt ttttcttgcc agctattgaa
    11341 aaagaactgg tagaacacgg ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta
    11401 gagacggctg ctttagcaga agacacagat tgggatactg aatatctaga ttatatcctt
    11461 gctgtcaaag tggtcgattc tttggatgaa gcaattgcac atatcaatcg gcataatact
    11521 aaacattcag aaacgatcgt gacagatagt tatgcggcta gtcaacgttt cttaaatgaa
    11581 gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt ttacagacgg atcggtattt
    11641 ggttttggtg cagagattgg tatctctact caaaagttgc atgcccgtgg tccaatgggg
    11701 ttaaatgaat taacttccac aaaatatatc atttatggcg atggacaaat ccgcgaataa
    11761 tgtttcgtgt gaaacattat tcccgccttt tgcctttttt ctgtaaaggt tctatccaac
    11821 tagaaaggtg tcaatatgtt tgaaatttta atgatttttt ttatttacct tatttctctg
    11881 aatatcgctg cttttctggg agtcggtatt ttatcccttt tctttcaatt caaaaaacga
    11941 agcataggga gtcaacggga aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg
    12001 ctggttacac gcttgcacat tagttacatg gttgcattat gcttattagc gacaatcaat
    12061 tactattctt ttttcgatca ttcaatcgct tatacgatta cgctactgat tgctgggatt
    12121 tttcacttat cttataaata tcagctgaat aaaaaccact tgaatcggac tttccgctaa
    12181 aaaatatccg tacgataagt agagtgcctt gaagatcggc aaaaaactgc cggacttttt
    12241 agaggctgtg acaaagattt tgtcacagcc tctttttcca tataaacggc gttcgcctac
    12301 cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg
    12361 ccatcataat aacgaagcag ctcatccatg gacaagttca tcgttttttc tttttcttct
    12421 tccgctgatt cagccagtag ctgttcccga tacacctgat acataccagc tattttttgc
    12481 tgcatcgctt ttctagtttc accttccgca ttgattattg gcaattcttt gatatagcca
    12541 cgataaatca accgatcatc tgaaaattca atgggtaatt caacgagtgt caacccgact
    12601 tcctgaaaat attcttccag catctattat ccccccattc tttttcttaa atgaatttta
    12661 gcttacctac tgaaaatttt ccagtttcat tattttgaga aaaaaaggga atgtgacaaa
    12721 aatcgtgtca catccccttt ttccgaataa atggtgttct tctgccaact cctcaatcat
    12781 aagtcacaat attcaacaaa catgagaaac tgttttttga aattgttcct tgtgattcag
    12841 agttaaacga cagtctcaca acctcttggt aaacggcgtt caatcagctg accctcggta
    12901 ttagctcaaa aaacggtaaa atatgagaag ctatttttcc gttttgtttc tctaatactt
    12961 aggataaaac gctgatttta caacctctgt taaacggtgt tcaatcagct gtccttcggt
    13021 attagctcaa aaaacggcaa aatatgagga actatttttc cgtttgtttc tctaatactc
    13081 aggacaaaac gctgatttta caacctcctg ataaacggtg ttcaaaagct tgcatctgcg
    13141 gtaataagcc caaccaaacg aaaaatatga gaagctattt ttgtttggct gttcttatga
    13201 cttgatgcag gacagctttt tcacaacctc tgatttctta ttcttcttca tttgtagcaa
    13261 aataattacg gtgataaatg atacaacata cactgataag aacaatggca cctgcaaaat
    13321 aaaacgcata gctttcacca atatgttcac caatcacacc tgcaataaat ggtgctaaag
    13381 ctccaccgaa aaagcggaca aaactatagc tggacgaagc aacgtttcgt tgcagacctg
    13441 gtatttccat agcaatcgtc gtcaacagtg tattgataat tccttggaaa aatcctgcta
    13501 acacaatgct gatcggtaca aggactggca tagaagttcc agctcctaat aacagcaaac
    13561 aaataatgaa taagacaaat gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa
    13621 gagccggtgc aacgaaaatc gaagcaatag ccagaagcac accccagcca aaaaatacaa
    13681 aaccgacttc taattcagaa tagccaatca ataaaaatgg cgcatacgca agtaaagtaa
    13741 agaatccgaa attatataac aatgcgatta gtccaactga acgaagttta tgattgctta
    13801 acgctttgac accttcccaa aggcctactt ttctctttgg tttctcagtt tcaggtaaaa
    13861 gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac
    13921 gccatgaacc actgcccaag accccaccga ctagagggcc aacagccatt ccgcagccaa
    13981 gtgctgcttc atacatcatg attgcttttt ctgtgttacc aactaaaata ctgacgatcg
    14041 ttgctaaagc agtagagaca aataaagcat tcccgacacc ccagccggca cgtaacccaa
    14101 tcagcattcc gatattccca gataatccgc caagaccagc gaatacaacg atgataaaca
    14161 atcctgtcat caatgttttt ttcaaaccga tccgactaga taagaaacct gtaaatagca
    14221 tcaccacacc agtgactaac atgtaactag taaataacag ggtcgtttca gctggcgtag
    14281 cgtttaactg tgcagcaatc gtttttaaga ttgggtctac tagacccact cccataaaag
    14341 cgatcataca ggtagctgct acaactagcg ctgaactttt cccctttgtt tcttcatttg
    14401 tttgttcttg tatatctatt tgattctcca atatttccat ccctttctct ctattagcat
    14461 catacatgat ttattttaca tgtcaatatg cacatgtaaa acgtggaaac tttactgtga
    14521 tataataaag aaaataagac gagaggtagg atttttatga atactttagc ctatatatta
    14581 ttatgcgtgc ttttatccaa accacgttct gggtatgaat tgaagcagct gatcacaatt
    14641 ttttgggaag cccatcacag tcagatctat acaacgcttg ccaagttaga ccagcagggt
    14701 tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa agatctacca cttgactgat
    14761 gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa
    14821 gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg ataaaacaac agctactgga
    14881 ctgctattca ctagagaaca acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg
    14941 aatgacctct cgctagacaa gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga
    15001 attatgcttt gtcagcagga actccaatgg tgtcagcaag taagagaaca aatgcagcag
    15061 ttttttgagt aagggataaa cagaaccttt ctagaaatat ctattgaaga gcaaattatc
    15121 ttcaataaaa gagcaataca gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc
    15181 tatcgttcgg atcactattt ttctagaact gcattcaaga gactatgaca aaaagcatgc
    15241 caaggccttt tttcaaataa cagtgttcca tcattcatta ctttgaattg cttttagcac
    15301 acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat
    15361 tttccaagca ttcatataag cagagaataa ttgatcaggt attccttgtt ccatgatcac
    15421 accgaataaa gacatacatg tcaccattcc taaaaccatc aagcatgaaa tagttaagat
    15481 catttggacc ttgctttctg gatttactgg tagtttaaag gcaatttttt tcgccagcac
    15541 accgatgatg aagacatcca aaatgaaagc caccacgaat ccaggcacta gaccaatcaa
    15601 caaacttgat aaatgaagat cttgatgcag ccataaatta tacgcgctca tccccaagac
    15661 catcaaaaaa cacatcattg ttgtaaaaat tattccttct tttttatttg taggcaatct
    15721 gtaccactcc tttaaatttg tcacgaaaat catcgtagca catttaaaaa tttctcgtaa
    15781 gtactttttt tattttctgc ccttttattt cataaacttc atcagccgta cgctcgacaa
    15841 agtaagaatc atgagaagta aacaaaatcg ttcccggata tatttgcatt agcttctcta
    15901 aagcttcgat cgttgccata tcaataaaat tagtcggttc atctaacagc aacacattac
    15961 ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc ttctccccca cttaatgtac
    16021 ataacggttt cgtcaaagtt tcctgagcaa accctaagtg attcagcaaa ctacggacaa
    16081 gcgattctga aaactctgtt tgtctcatga caaaacgaat gatggattct tcagatgtca
    16141 tttgataacc cttttgctga tatacttgaa agcttacttt cggagagaga aggattcctt
    16201 ctccttgttt gcggatatgt tctaataagg ttgtcttacc tgaaccattt tcaccgacaa
    16261 tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt taccagtaat gttctcccac
    16321 ttctttccaa ttggacattt tgtcccatga tgggatagcg gctgtggagt tcaagagatt
    16381 ttggtactgg aaaacggatt tgtttcatct gctgcggctt ggttgtttct cctatttttt
    16441 ggagtcttct ctctaatgtt ttcgcattct tttggatggc tttttgtaca ctgtcttttt
    16501 gtttagagga agacaaccga tccagtctga tttgttgctt tttcttttta ctggacactt
    16561 tttccaactt ttccgcttgt tttttctttt cttggatcga tttttccaat cgttttttct
    16621 ctttcatgat cgactctgct tctcgtagct gagtcttttt ctccaattcc ttttgagtga
    16681 gataggcact ataattcccc gaaaactctc ggatttctcc gtcttttact tcccagattt
    16741 tcgatgctag ctcatctaga aaatagcgat catgactaac aaaaaccagc gtaccataat
    16801 aataacgaag ctcttcaatc agtcgatcaa tactttttct atctagatgg gttgttggct
    16861 cgtctagaag catcccttgt tcataagaag aaagaagacg tatcaactcg atctttcgtt
    16921 cttcccctcc gctccatttc cgctctgaag tttcttccag tcttaactgg aaatgactgg
    16981 ctaattccaa atttaggtcc tttgcttcag cgagataggt taattgaggc aggtagttga
    17041 aggtgatctc tgtttggatt ttcccatgat cgggaaaaag ttcaccggct attagtttga
    17101 gcaaagtcga tttaccgaca ccattttctc ctatgatccc tatacgatct tgctgataga
    17161 cacgaagaga atcaatagat agttctagct ggttgccaaa gctgacttgt agatttgtta
    17221 tatttactgc taaattttcc atatgtttta cactcctatt tcatgtaaaa caacaattat
    17281 cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta
    17341 ctctgaacga aataactatg actaaatcac caaatctgtc atagctttca cctattctac
    17401 tgtcgttcga aaaaatggac atactccatc catgaaattg ttgtttatac atgtcttttg
    17461 aatttattta gttgttattc aaaagttcga aacgtaattt catcgatgca gtcatttttc
    17521 cgacctcctt ttttattagg ttaccacaca cgattcaaaa aaagcaatag ctactgaata
    17581 gtaactgaaa accttttatt cgaacatagt gatcttttct ggtgctaaac gaacagactc
    17641 gtaaccttct tctaccgctt ttcctattga taaaataata actggaacat aacggtcttt
    17701 atccaaacca aatgcctctg ccaactgatc tgcttcgaat ccaccaattg gatttgtttc
    17761 atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc gctaagctag aatcgacttt
    17821 gactacatcg ttcatttctt ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa
    17881 ttgttgatct ctgacttctt ttggcatctt ccctgattcg taagcttggt tgtagatttc
    17941 ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg accattgcag aagaagtatc
    18001 attttgtctc gtattgaaac ggatcaaagg acgcaagatt tcttttgctt cctcgctttc
    18061 agcgaccaca aagcgccatg gtttcatatt gacagaagaa ggtgcagtcg tcgcttcttt
    18121 gatcatttcc agcatttctt cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga
    18181 tcttctacca gtcataattg ttgaaaaatc atttttttgt tccattatta ttaacctctt
    18241 tcgtttctgt tgttatattg caaagttggg tattcaattt atctaaaagt gttagaaatt
    18301 gtttcatttc tacatcgctg aaagccgggg atagcacgga acctgtatct ttatggtcca
    18361 tttcacaatg cttgattttc ttctgggctt tttctgttag cgctacatac acttcccggt
    18421 tgttctgagg atttctctga cgcgaaacat agccatttgc ttccaatacc ttcagatgac
    18481 gagtaactgc tccttgatca atctgcaact tttcttgcaa actgctttgt agcaatggat
    18541 tttcttcttt cagtctcatc atgatctcgt atctagtaag acttataccg atattttctt
    18601 caaagatctg gacgattttt tgatcggcta atttgatttg atataaaagg tgactaatct
    18661 cttctaaaga cataatttcc tcctttctaa taattgactc gtcaacgatt gacttgtcaa
    18721 taatagaata aaaaaagaaa aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc
    18781 aatagaaaag tatagagaaa agaaattttt tgtagaatga acggaaaaaa tgataaagaa
    18841 agcacaacgc taaaaccaag attattgatt cttatcaaac tatagaagat agctcttctg
    18901 cagtagataa ttttacaccg ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg
    18961 aatattagaa attggatcag tatgcttaaa cagtaataaa aaagttatga caagatgttg
    19021 tcacaacctt ttttgagtaa acggtgttca aaaacttgca tctgcggtaa taagttcaac
    19081 caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc ttactacttg atgcagggca
    19141 gctttttcac tacctctttt taataaccat aaaatcctat tccttcatat ctccagccca
    19201 tcggtgttag ccaatctctt tccttagcac tcaaggtata gtgatgggta ccagtttttt
    19261 catttggatt aaatagtcga taaattggct tggaaccacc agaataaaaa cttagacctt
    19321 cataacgcca accgattttt gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat
    19381 ggtctccact gtaaggattg tataaacggt agacaggttg tccgctgttt ggtgcttgcc
    19441 aagcaatccc ttcatattcc cagcctacag ttggcagata atttttttct ccggcattca
    19501 atgtatataa atgttctcct gtatgacggt tatacagacg atacatcgga gaagttgaag
    19561 ttggtgctgt atcatactgt gtcagattat aggtttcgat tacattgttc aatgtagaac
    19621 cataattagg cgcagtggca taacgacctg ttagccaagc cgtagcatct ttgtaagagt
    19681 tcgtattgct tttccatgca ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct
    19741 tcaataccgt tacgttatct tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg
    19801 cattcaccgt aatccattgc ccattcacat attccgaagt aggcatcgta acagattggc
    19861 cattatagct tcctttaatc ccaaatagat tgtaattagg ggcagaagcc aaagtactgt
    19921 tcccccagcc actttcaacg atggcttgag caatcatgac tgatgcatat aagtcattgg
    19981 cacttgccaa actttgtgca gttgaggcaa tactatcaat gaacgcttgt tgagaattag
    20041 cagatgagcg agcataaaaa gcatagccag tatagttttc gaattcagac aaatctgctt
    20101 gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt cgtgatttct tctgcattct
    20161 ctggattgtt ctgagcttct gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt
    20221 cagttgttgg ttcttcggtt gaaattgtat tttctgagac agtagctgac tgcaaagtac
    20281 tttctgtatc gttttcaatt cctgtttctg aagaactcga tgtctgagtt gcgacagttt
    20341 ctgtcgattc ttcagctagc actgttgtgt tggcaactgc tagatttcct aaaagaataa
    20401 cgctaaataa taaattcttt gctttcatct tttttctcct ttgaattatg aaacttttcc
    20461 taaataacag tgtaactaaa aaagtaaaag caagtcaatg tccatattta aataacattt
    20521 gtttcttttt aataaatttg ctttttctgc ataaaaagac gtaaatgaag aatattcttc
    20581 tccattcacg ccttaaattg atggtcgttt gaataactat ttaacaagta attctctctg
    20641 gatattatcc gttatggatt atacttcctg tgtcgtcgga cggataatca tgttgctgac
    20701 agacatccgg tctggcgttt ctatcgcaaa tgctacagca gaagctatat cttcagatgt
    20761 taatccccat tctttttgcg cttcatgaag ttcaagagca gcctttttgt cgctgatggt
    20821 ttgatataat tcagtttgaa cagctcctgg agagatgatc gtagatttga tgttattttg
    20881 ccgttgctct tgacgtaatc cttccatgat tgcacggaca gcaaattttg ttccgcaata
    20941 aacggcggaa tcaggataaa caacatgtcc cgccacagaa tcagttgaaa tgatatgccc
    21001 agatttttgt ttttccatga ttggaagtac ggcggaaatt ccatttaaca cacccatgat
    21061 gttgatatca agcatatttt gccattcatc acggtgacct tcaactaatg gagcggttgg
    21121 catgattcct gcattattgt acaatacatc gattcgaccg aacttttcca tcgctaaatc
    21181 gataactgct tggacttgtg caaaatctct tacatctgct gtttgaatat atagctcagc
    21241 ttctggtaaa gattctttta ttgcttttag gcgatcttct cggcgtgcag ctataactag
    21301 tttagcccct ttttctgcta atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc
    21361 catgatgaca atcacttttt ctgataaatc attcattcta ttctcctcct gttttgaaaa
    21421 atctcttgct tatactcact atctcttatt tcatcttact gttcaaataa tccgttcgac
    21481 aggtttgacg attttggcag ggattcctgc aacgatggta ttgtctggga catctttcgt
    21541 aacagttgca ttcgctgcaa caatggcatt ctcgccaatc gttacgcctg gcagaatagt
    21601 tgctcctgct ccgatccaag catttttctt gatgtggatt ggctttactg acaagcctct
    21661 tcgttctttt ggatcggtta gatggttcac cgtgatgagg ttgacacgag gaccaatcaa
    21721 tactgaatct tctaaacaga tgccacctaa gtcaacgaac atcacttgac gattgataaa
    21781 gacatttttc cctatactaa tatgtttgcc gaaatctgta taaaaaggca gcagaacagt
    21841 caccgtatca tctactttgt cactaatgat attttctagc cgtttgcgga tatctgctgg
    21901 ttcatggtac ccagtattca gcgctgctaa aggctcttcg ttttccgctt ggatctgatg
    21961 gatcacttca aagagcggat ccgttactcg aatctcttta ttgacgattt gtttttcgat
    22021 gaggcttgtc attttgctcc ctccttttat ccttacttta taacggacgg cttatgatgt
    22081 ctaatactta taaaacatac ttaactattc cttttaacta tacttagtgg tatgcttttt
    22141 taaaaacagg agggaaaaaa tggatattcg tatactgacg tattttttag cagtagctag
    22201 agaaaaaaat atcagccgag cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa
    22261 acaactgaaa gatttagaag aagaacttgg tgtgacactt ttcactcgag gctcccgaga
    22321 gatacagttg acggattctg gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt
    22381 ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc atctctggag aaatctacat
    22441 tggcggaggc gaaactaaag caatctcttt catttctgat agccttcatt cgttgatcaa
    22501 ggcgcatcct gatatccagt ttcatttata tagcgggaat gcagatgata tcatagacaa
    22561 actggatagc ggattacttg attttggact cgtaatcgaa ccgacaaaca aacaaaaata
    22621 ccagtcattt cgactgccag cccaagatcg ttggggactt ttgatacatc ggaatcatcc
    22681 tttagcaaag caaacagtca tccatccgca ggaactgaaa actgttcctt tgatcatttc
    22741 ccggcaaacg tcagtggaca gtcaactagc tgaatggcta ggtttcagca tagatcagtt
    22801 atcgatcgtc ggaacatata acttattgta caatgcttct ttgatggtcg ataacgggac
    22861 ttttggtgca ttagctctag atgggatcat caatacttat gggacggaaa aagtattcat
    22921 cccactcgat ccgccattac aagcttcact gaatctcatt tggaaaaaag accagcctct
    22981 ttctcctgct gctcgtaaat ttttagatgt cctaacggag aaatacagtt aagtagagtt
    23041 tttttccttc gctttcagct ttttaacaac gaataagtta agcaaaagat ccaatgatta
    23101 aataacataa gtttcttaat ttgttccttc cttttatttc t
//
LOCUS       DACCVH010000040        23121 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.040, whole genome shotgun sequence.
ACCESSION   DACCVH010000040 DACCVH010000000
VERSION     DACCVH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.040"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            247..2718
                     /locus_tag="IVV98_001603"
     CDS             247..2718
                     /locus_tag="IVV98_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7807263.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2821..4557)
                     /locus_tag="IVV98_001604"
     CDS             complement(2821..4557)
                     /locus_tag="IVV98_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP7807264.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4554..5258)
                     /locus_tag="IVV98_001605"
     CDS             complement(4554..5258)
                     /locus_tag="IVV98_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7807265.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5389..5892
                     /locus_tag="IVV98_001606"
     CDS             5389..5892
                     /locus_tag="IVV98_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP7807266.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5852..6190
                     /locus_tag="IVV98_001607"
     CDS             5852..6190
                     /locus_tag="IVV98_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP7807267.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6211..7629
                     /gene="ffh"
                     /locus_tag="IVV98_001608"
     CDS             6211..7629
                     /gene="ffh"
                     /locus_tag="IVV98_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP7807268.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7741..8319
                     /locus_tag="IVV98_001609"
     CDS             7741..8319
                     /locus_tag="IVV98_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP7807269.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8323..8844
                     /locus_tag="IVV98_001610"
     CDS             8323..8844
                     /locus_tag="IVV98_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7807270.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8923..9477)
                     /locus_tag="IVV98_001611"
     CDS             complement(8923..9477)
                     /locus_tag="IVV98_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP7807271.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9730..10005
                     /gene="rpsP"
                     /locus_tag="IVV98_001612"
     CDS             9730..10005
                     /gene="rpsP"
                     /locus_tag="IVV98_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP7807272.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10017..10268
                     /locus_tag="IVV98_001613"
     CDS             10017..10268
                     /locus_tag="IVV98_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP7807273.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10393..11184
                     /locus_tag="IVV98_001614"
     CDS             10393..11184
                     /locus_tag="IVV98_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807274.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11354..11875
                     /gene="rimM"
                     /locus_tag="IVV98_001615"
     CDS             11354..11875
                     /gene="rimM"
                     /locus_tag="IVV98_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP7807275.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11865..12626
                     /gene="trmD"
                     /locus_tag="IVV98_001616"
     CDS             11865..12626
                     /gene="trmD"
                     /locus_tag="IVV98_001616"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP7807276.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12762..13109
                     /gene="rplS"
                     /locus_tag="IVV98_001617"
     CDS             12762..13109
                     /gene="rplS"
                     /locus_tag="IVV98_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP7807277.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13482..14144
                     /locus_tag="IVV98_001618"
     CDS             13482..14144
                     /locus_tag="IVV98_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807278.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14223..17450
                     /gene="fss3"
                     /locus_tag="IVV98_001619"
     CDS             14223..17450
                     /gene="fss3"
                     /locus_tag="IVV98_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP7807279.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17564..17878
                     /locus_tag="IVV98_001620"
     CDS             17564..17878
                     /locus_tag="IVV98_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7807280.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            17891..18265
                     /locus_tag="IVV98_001621"
     CDS             17891..18265
                     /locus_tag="IVV98_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7807281.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18275..18619
                     /locus_tag="IVV98_001622"
     CDS             18275..18619
                     /locus_tag="IVV98_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP7807282.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            18690..20042
                     /locus_tag="IVV98_001623"
     CDS             18690..20042
                     /locus_tag="IVV98_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP7807283.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20102..21244
                     /locus_tag="IVV98_001624"
     CDS             20102..21244
                     /locus_tag="IVV98_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAP7807284.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21269..21523
                     /locus_tag="IVV98_001625"
     CDS             21269..21523
                     /locus_tag="IVV98_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807285.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            21779..22963
                     /locus_tag="IVV98_001626"
     CDS             21779..22963
                     /locus_tag="IVV98_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7807286.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            22978..23097
                     /locus_tag="IVV98_001627"
     CDS             22978..23097
                     /locus_tag="IVV98_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP7807287.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
BASE COUNT         7685 a         4108 c         4973 g         6355 t
ORIGIN      
        1 ttttggtcga ctaaatttta ccaaaagtga gtctcttttt gagttgaaac gaagaaaaag
       61 tgttagtaga aaatcgcctt cgattttcca ccaacacaaa atattataga accctttttt
      121 tttgctatat gacaggaatg aaaggtgttt gcaagcttaa tgtgaggaac actttccata
      181 tctgttctat actggatagg agaagtttgg aaatatccag aaaacgaaat caatcgaggt
      241 agccacatga agaataaatg gataaatcga agtaaaaaaa agaaagtaac acaaagatca
      301 tcagataaag tcatccgtct ttttccatcg tataaagaag gattaacggc agatcaagtc
      361 aaggaacgaa tagaaaaagg tgcagcaaat aattcagtcg atcccacatt caaaacaaat
      421 cagcaaatcg tattggaaaa catatttacg tatttcaatt tgatctttct tatcttagcc
      481 attttgcttt gtttagtaga atcctataag aacttgactt ttttaccagt tatcatagcc
      541 aatacaggaa tcgccatttt tcaggaaatt cgatccaaaa agatcttgga cgaactaaat
      601 gttttaaata cagcaaaagt caatgtcata cgagacggga tagaacaaac aatagatata
      661 gaagaccttg taatagatga cattgttatt ttagagactg gatatcaaat tccagcagat
      721 gcagaggtcg tggaagggaa actgcaagtt aatgaggctt tattgacagg cgaagcagat
      781 gaaataacca aagaaatagg tgatccatta atgtccggca gtttcattgt ttccggaaaa
      841 gcttacgccc gattagacaa agttggagca gattcgtata tttcccagct gacagtcaaa
      901 gccaagacaa tgggagaagg agaacagtcg gagatgattg cttctcttaa tcaattgatc
      961 aaatggattg ggatcatcat tattcctatc ggtatcctgc ttttttctca aagttacttt
     1021 tttaatggaa acacgatcaa agaaagtgtc gttgcaatgg aagcagcatt gatcggtatg
     1081 atacctgaag gactgtactt gctgacgacg attgcattag cattaagtgc gactaaacta
     1141 gcaaagcaaa gagttctttt acacaatatg aaaagcattg agacattggc aagggtaaat
     1201 gtcctttgtg tagataaaac aggaacgatc acagaaaata aaatgtctgt tcaaaaaatg
     1261 atcgtctcta aaaaacaaga aataatcagt cagtcagatc aattggaagc atgcattgct
     1321 gactatgcaa aagcgatggc aggagacaat gcaacaatgg aagctgttaa agcatatttt
     1381 acaaaaacca ctgatcaatc ctatcaccat gttattcctt tttcttctgt ccaaaaattc
     1441 agcagtgtag cgttggcaga caaggtgtat gttttaggag cgcccgaaat ggttttgcgc
     1501 gatcaattgc cggaatatgc ggaagagttt gtttctttcg ctgaaaaagg ctatcgcgtg
     1561 ttggtctttg gtgtgtacga tgggattctt gaagaaccag tattgacaga agcagtcaca
     1621 ccattaggct atattctgat tgctaatcct atcagaaaag aagcaagagc cacatttgat
     1681 tacttcaaaa aacagcaagt agccatcaaa gtgatttctg gagataatcc gctcaccgta
     1741 tccaatgtag ctgtccaagc agggatttca catgctgatc agtacgttga tgcatctaaa
     1801 ttatcagaag aagaatatga agcagctgtc gaaaaatata cagtttttgg acgcgtcaag
     1861 ccagaacaaa agaaaatctt cgttcaattg ataaagcgta acaatacagt agctatgaca
     1921 ggtgatggcg tgaatgatat tctagccatg aaagaagcag actgcagtat agcgatggct
     1981 tccggaaatg aagccgccat gcaggcctca caagtggtct tacttgattc tgacttttca
     2041 cgcatgccag aagttgttgc agaaggacgg cgcgttgtga acaatattga gcgatcagcc
     2101 agcttgtttt tagtgaagaa tattttctcc tttttgctct cactgttttc agtgatcttt
     2161 gctctgacct atcctttaga accatcacaa atcacattga ttagtttgtt tactatcgga
     2221 cttccatctt tcttgcttgc tctagaagaa aacaaaaagc gaatcagagg gaaattcatc
     2281 atgaatgtga tggaaaaagc tgtgccaggt ggactaacag atatgatcgt agtcggtgcg
     2341 ttggtgatct gcggggtgac tttgaatcta aataaaacag atgtttctac agcatctacc
     2401 atgcttttga ttgcagtagg gttcctcgtt ctctataaaa tctgttcacc gctgaataaa
     2461 ttcagaagtc agatcattct tttctgtgct agcggtaact ttttttcggt catctttttg
     2521 cataagctgt tttcaatcac cggtatctca gctgtatcac ttttgctgtt gagcattcta
     2581 tttttctcgg cagattcgat ttttaggcat ttgaccacat tggtagaata tttgtttgaa
     2641 cgtaaaaatg aaaaagagca aaagccgttt agtcgcgtag ctaaaaaatt tctatcgata
     2701 tttaaacgag aaaattgacg aaaagtatct caaaaaagag taaaaaagaa caaccactcg
     2761 tgtatctttc gaagcaggat gagtcatcca actttaaaac gcacgagcag ttgctctttt
     2821 ttacattttc ggaatggtaa cggtgaaagt cgaacctgtt ccaagatgac tgtctacagt
     2881 aatcgtacca ttaaggagtt gcacgtagtc ttttacaatc gctaacccta atccggtccc
     2941 gcctgaatgt cggcttcgcg ccttgtctac gcggtaaaaa cgctcaaaga tccgttcctg
     3001 atcctcaatg tcgataccta taccaaagtc ttggacagaa aacgatagat catctgttgc
     3061 ctgatagcgg ataataatct cgctgtcgct ttttgaatat tggacagcat tttcaattag
     3121 atttttgata attggataaa ggatatctgt tttagtagta aatggttcgt tctttccaat
     3181 caatcgaatc gtcaaccgtt tcttttcgat gattggctga taattttgaa cgatttgctg
     3241 gaaataaggt tctgtataaa ttgtctggat ctcgtaagaa ttctcgccat cttttgacag
     3301 ctggatgatt tcccgaatca gtttatctaa ccggatcgca tctttttgca tgatctcaag
     3361 aaaagaagtc agagtttgcg ggtcatcttt tgcaccatcc agtaaagtct cggtaaaacc
     3421 aatcagtgaa gtcacaggag tttttaattc gtgagagacg ttgccaacga aatccttttg
     3481 tagcttttct aaacgtcgca ctttcgttaa gtcatacgcc acccctagaa tctgtccggt
     3541 accttctgaa ttagtaaagt agcgcaaact caagtctaat gtctgccgac cttctgtaag
     3601 ggtgatctcc tgatggatca gcggatgctc aggagtcact tgatgaatca gctgaatgag
     3661 ttttggctct tgaatgactt ctgtgtaccg ctgttcaggt tgatagctta ccacgtttaa
     3721 atgtagctgc atctttggat taagcagtag taaacgagaa tcagcatcat caatcaggaa
     3781 tacgccaatc atcagttcgt tcagtaacgt atataattgc tcttctgtgg tagtacacgc
     3841 ccgatacatc ttactcattt gttcgctcaa cgcattaatc gtctgataca attcttccca
     3901 ttgatcgggt gtttgcatga ttacttccgc ctgattagga ttttgcacca ttttttttag
     3961 tacgggcagc acggttttca atggctggtt tttttgatag atcagataat agatcattcc
     4021 tgcaagaaca aggaagaaag acagaaagaa gaaaaagacc caacggcgaa aactctcagt
     4081 tctcggtaaa aaaccgcttg tcggttctgc gatacgtaaa atggcttcta actggccact
     4141 ttttttgact ggtaatgcga catataaaag atcctcattc aaagtagtac ttttgcgcaa
     4201 agcgctacct aggttcccac cattcaatac ggctttgatt tcgggacggg agtttcgctg
     4261 ttcattcaat gtttcattgt ttgtgtcaaa taagatcttt ccagtagcat ccattaaagt
     4321 aatccgttcg ttcgactgat ggacgaattc ttccaaagca gttttgtttt gcgctgcttg
     4381 gaggttttcg acatctaatt gccggatcag cagttgtgct ttttttgtca ggtagctttc
     4441 ttgctgttcc acgatctgct gttgaaaata atgggaaatc aattgccagc caccaaaaaa
     4501 caaactaact aaaagaataa gaaagaagag acgttcataa atttttttcc atttcatcgt
     4561 ttgggttcct gaaacttata gccaaatcct ctaatagtca ccaagtactt tgggtgtttt
     4621 ggatctcgct cgattttttc tcgcaaatga ctaacgtgta catctacgat tcggctttgt
     4681 cctgcgaagt caaaattcca aatgcggtct agcaatgtgt ctcggtcgat cacacggtct
     4741 tttcgtttca tgaaataaac aagtaattca aattctttcg gtgttagttc aatcagatgg
     4801 tcgtctacgg tcacttgata attggtcaaa tcagcagtga tttgtccaat cgatagatat
     4861 tcaggctcag cttcatcttt tgattgctta cgaggttcaa ttcgtctgaa tattgctttc
     4921 atacgggcta atacttcgcg aggactaaat ggtttggtca aatagtcgtc agcacctatt
     4981 tctaggccaa tgatccgatc cacttggtca tctttagccg tcagcatcaa aatcggtgtt
     5041 tcattttttt cttgacgcag ccgctgagtg atctccatgc catccatcgt tggaagcatc
     5101 acatctaaaa tgatgaaatc aaatgattgt tctaatgcta attctaatcc ttcgcctcca
     5161 tctgtggcac tggttacctt gtagccttct ttttccaaat tgaacgtcaa gagcgttaca
     5221 atagaaggtt catcatcaac aactagtatt tttttcattc aaatctcctt taaataggtt
     5281 tcattctgtt tatattttag catagaatca gtacaaaggg ctattttaca aaagaaataa
     5341 atggtataat aggaaggcac tttgctgaat agaaaggaag agcagtcaat gattggaatc
     5401 agtgcatgtt taggcggtct ggcctgtcgc tatgatggac agaaaaaaga agtaccagaa
     5461 ttgatggaac tagttgaaac tggagaagct gtcatggtct gtccagaagt gatcggcgga
     5521 ttaccaattc ctagagatcc cgctgaaatc attggtggaa atggattcga tgtgtggaaa
     5581 gatcaagcaa aagtatggac gacaagcggc gaagatgtaa cggaagcgta caaaaatggc
     5641 gcgatcaaag cctatcaaaa attgcaggaa aaacacattg atctagtcat catgaaggaa
     5701 aaaagccctt catgcggaac ccattcgatt tatgacggaa gtttttccgg aataaaaaaa
     5761 aatggtgccg gagtggctac tgcttatttt attcagcaaa aaatgactgt gctctctgat
     5821 gaagaatggc tgaaaactag aggtgagcag aatggaaatc gaaaagacca atcgaatgaa
     5881 cgcgctcttt gaattttatt cgaccttatt gacagaaaaa caaatgaact acatggaatt
     5941 atattatgca gatgattttt cattaggtga gatcgcggaa gaatacgaag taagccgaca
     6001 agcagtatat gacaatatca agcggacaag caagatcttg gaggattatg aaaaaaaact
     6061 ccatcttttt tctaattata ttgttcgaga acaggtattg gaaaatatga ctgcatatat
     6121 tacagataag tacccggaag ataaaaaact acttgaatat gtacagcaaa ttcaagcaat
     6181 cgaagaataa ataaaaggaa tgaagaaaat atggcatttg aaagcttaac tgaacgtctc
     6241 cagcaggcga tgggaaaaat aagaaaaaaa ggaaaagtat cagaagctga cgtaaaagaa
     6301 atgatgcggg aaatccgcct tgccttacta gaagccgatg ttaacttgca agtagtcaaa
     6361 gattttacta agcgcgtacg cgaacgtgcg gtaggggcag aagtgctgga aagtttatca
     6421 cctgcacaac aaatcgtaaa aatcgttgat gaagaattga cgatcacact tggttctgaa
     6481 acagcagagt taaataaatc accaaaaata ccaactgtta tcatgatggc tggtcttcaa
     6541 ggggcaggta aaacgacctt tactggtaaa ttagccaatt atttaaagaa aaatgaaaat
     6601 gctcgtccgc tcctaatcgc aggggacgta tatcgaccag ctgcgatcga ccaattgaaa
     6661 gtattaggtc aacagctaga cgttcctgta tttgatatgg gaactgaagt cagcccggta
     6721 gagatcgtcc gtcaagggat ggagttagca aaagaaaaga aaaacgacta tgtattgatc
     6781 gatacggcag gacgtctgca tatcgatgaa acattgatgg atgagttgaa acaaatcaaa
     6841 gaattgacgc aaccaaatga gattttgctt gttgtcgatg ccatgactgg tcaagatgcc
     6901 gtcaacgtag ctgatagctt caaccagcaa ttaggtatta caggggtcgt catcactaaa
     6961 cttgatgggg atactcgagg cggggcagca ctatcgatcc gctcagtgac aggcgcacca
     7021 atcaaattca tcggttctgg tgaaaaattg actgacttag aagtattcca cccagatcgt
     7081 atggctagcc gtatccttgg tatgggggat atgctgacat tgattgaaaa agcgcagcaa
     7141 gactacgacg agaaaaaagc ggaagaactt gcacagaaaa tgcgggaaaa ttcattcgat
     7201 ttcaatgact ttattgaaca gcttgatcaa gtgatgggta tgggcccact ggaagatcta
     7261 atcaaaatga tcccaggaat gaatcaagtc cctggaatcg aaaacgtcaa ggtagatcca
     7321 aaagatgttg aacgcaaaaa agcgatggtt tattctatga cgccagcaga aagagcaaat
     7381 cctgatctgt tgaacccaag ccgtcgtcgc cgaattgctg ccggttctgg aaacagtgtt
     7441 gttgaagtga atcgaatgat caaacaattc aaggaatcaa gaaaaatgat gcagcaaatg
     7501 tccaaagggg atatgaacat cccaggtatg gaccaaatgt ttggttcagg cgtcaaagga
     7561 aaactaggca aaatggcgat gaatcgaatg atcaagaaaa ataagaagaa aaagaaaaaa
     7621 cggaaataag atgaaaaaaa cagcttcggt acagactgaa aatgtctact gccggagctt
     7681 ttctatcagc aatttttatt ctttactaat acaattactc taaacgaaga ggtggcacag
     7741 atgagatgtc cgtggagtga acaaacagaa agtatgcggc aatatcatga tactgtctgg
     7801 ggtgttcctg aatatgatga ccaaaagctg ttccgaaaat tgatgcttga tattaatcaa
     7861 gccggattga gctggcagac gattttaaat aaaagtgaag cattcgatga agcatatgat
     7921 cgattcgata tcaaaaaagt cgcaaattat ggagaaacaa aaatcagtga actaatggaa
     7981 aacaaaggaa ttattcgtaa ccgaagaaaa atcgaagcag ccgtccaaaa cgccaaagca
     8041 gtcttgaaaa ttcaagaaga aatcggcagt ttttcagagt atctttggtc gttttctaat
     8101 ggaaaaatcg ttgattcttc ttatcattca caagaagaag tcccaacaac aagtcctctt
     8161 tcagatgaat tagcaaaaga tctaaagaaa agaggattta aatttatcgg aagcacaaca
     8221 atctatgctt ttttagaagc tgtcgggatc atcaatgatc accttgacag ttgtttccgc
     8281 aaagaagagg tcgtacgtat cggcagaaag ggcgaataaa gcatgcgaaa aatcatattt
     8341 tatggtgcta taagtttaga tggctatttg gcaacgaaaa cggatgatct tcaatggctt
     8401 tttgacactc caacaggtaa gcaaactact tatgaagctt tttatgaaac aatcgatacg
     8461 accatcatgg gcagaaaaac ttatcaggaa gcaaaaaaat atttggagac cgaagcaatt
     8521 tatccagaga aaaagaattt cgttttttcc acccacgcac aattacaatt gccagatgct
     8581 gaggtcgtaa acgaagatcc tgttgctttt ctaaaaaatc tacaaatgac agaaggaaaa
     8641 gatatctggg ttgtgggtgg cggtcgattg atcaaaccgc tattggaaca tcaaatgatt
     8701 gatgaatggt atatccagat tacccctgta ttattagggg acgggattcc tttattccaa
     8761 aaaggaacat atgaagcgcg ttttgaaatg ctagacacga cacgattcgg tgaatttatc
     8821 gaattgcatt atgtacgaaa gtagaagtaa ataaaataaa aaaggcaact atatgcagaa
     8881 atgtcctgta catagttgcc ttttttatta ccgttatgct ttttactctg ttaatttgtt
     8941 agaaaaatct agatacgcat ctaaaatcgt ttggaagaaa cttaatgttc cttcaacgat
     9001 attaccattt tcatcaatta gattcgcaac gtttccgata tatgcttccg gttgctgcaa
     9061 ggttggcaca ttcaaaaaga caagtgattg gcgtagatgg tggtttgcgc caaagccgcc
     9121 gatcccacct ggtgatgcag taacgactaa acctggttta tgatcccaaa cactgtgtcc
     9181 ataaggtctt gagcctacat ctaaagcatt tttcaatact gctggcacag aacggttgta
     9241 ttcaggagta acgaaaacga caccgtctag tcccctcact tcctcacgaa aacgagtcca
     9301 ttcagcagga gcctgttctg gagtttcgag atcctcattg taaaatggca gatcatcgat
     9361 ttttacaaat acactttcgt acccttcagg aagcaatttc gcaaaagctt ctgctacttt
     9421 tttgttgtaa gaatcttttc ttaaactacc aataaaaaat ccaatttttt ttgtcatacg
     9481 atttttcctc cttcaaacta tctataataa tcttacaaaa gataagtaac tggagcaaat
     9541 aaaaacactt actgacaaaa gctacataga agatagatta cttattttta acaaaaaaga
     9601 agtctaaaat cttctatttt ctaaaaaaaa tcgaatttaa tcaagctgta aagaaaaaaa
     9661 gctttacagg gtaaaaaaaa actgttacac tacatcttgt gaataaaaca atggaggtgg
     9721 aaataaataa tggcagttaa aatccgttta aaacgtatgg gttctaaaaa gagtccgttt
     9781 taccgtatcg tcgtagctga ttcacgttct cctcgtgatg gacgtttcat cgaaactgta
     9841 ggtacttaca atcctttgaa agaccctgca gaagtagttt taaaagaaga cttagttctt
     9901 gactggttat caaaaggtgc acaaccttct gacactgtac gtaacatcct ttcaaaagaa
     9961 ggcgttatgc aaaaacacca cgaagctaaa ttctcaaaga aataaggtga ccggatatga
    10021 aagatttaag cgacttagtc ttaacaatcg ttcgtccgct agtcacttat cctgatcaag
    10081 tcaagttaga cgtcgtagag tcgaaagact tttacgagta caatctaaca gtggctcctg
    10141 aagatattgg ccgtatcatt ggaaaacaag ggcgtgttgc taaagcaatc cgcacaatcg
    10201 tttacggtgt tcggatcaat gcaccgaaaa aagtgcgttt gaatatcatc gatgataagg
    10261 aaaagtaaat aaacgtgctg tactcgaatt ttcgagtgca gcttttttgt tttttttatt
    10321 aattgaagaa atgattattt ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg
    10381 agtgaacagc caatgagaaa gaaaatgtta tttattccat ttgctctatt gttaagcgct
    10441 tgtagttcgg ttactcaaga atcagacaat acacatctat caagcagtat atctgaaact
    10501 gttaccagtc cagaaaaaag tagtaccaaa acggcttcca ccactgaaca aacaatggct
    10561 acctcaaata atgagaaaaa gactgcttta gaccagttga aagaacaaca gccaaatgtt
    10621 cccatgcctc tagatgtacc agtctcttca ggctatctca atatcgcagc gacacataca
    10681 aagcaaggtt attctatttt atattacaga acagatcgtc ccctcgggtt gaatgctgac
    10741 gaattgaatc aagaaacgcc tattgcaacc tatctatatc aatatgggtt tgcttctagt
    10801 caagaaacaa tccaagtttt gcagccattt gagatcgaca caaatggtca gcaagtggac
    10861 ttaggttctc gaatcacagg gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg
    10921 caagaaggaa actggcgtat tcgaatccgt gggaataata tagaaggcca agatccctta
    10981 ctattagcta aagaaatcgt agcttatttg gaagaaaaca gtctaccagc acctgaacaa
    11041 tttggtaaaa ttactgttga tatgggtgat acgacgaatc gagccgtaga agtaagctgg
    11101 caagaaccga aaaatgccta tacgatcact catcaagatc ctatgtctgc gttgaagatg
    11161 gcagtttcta tgaagaggtt gtgaaatcag cgcgctgatc tgagcccatc atttaactcc
    11221 aagtcacagg aagtaatcaa aaatagcacg ccgcattttt gcataatttt ggcttaatac
    11281 cttaaaagaa aactagaatt gcctcttcac acatgctaaa ataaaacaga caaaaaagaa
    11341 atggggatat aagttgactg aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat
    11401 caaaggcgaa gtccgtgtta tctcaacaac ggatttccca gaagaacgtt acaaaaaagg
    11461 aacggtgcta acactattcc aagacggaaa agcacctgtg gaattaacag tcaaaagtca
    11521 tcgcaaacat aaaaattttg acttattgag ttttgaagga catccttcta tcaatgatgt
    11581 ggaaaaatat cgggatggca tattaaaagt gtcaaaagac aactctgtag atctagctga
    11641 aaatgaattc tattaccatg agatcatcgg tctgcatgta ttagaagatg gaactgagtt
    11701 aggtaaagta aaagaaatct tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc
    11761 gaaaaaagct gatatattgc ttccatatat cgcttctgtc gtcaaagaag tcgatttaga
    11821 agctggagtg gtccgtgtag aaattccaga aggactgatt gacgatgaag attgatgtat
    11881 tgactttatt tccaagaatg tttgaaggtc ctatggggga atccatcatc ggtaaggctg
    11941 tagataaagg attattagat atcaatatct ctaacttccg cgattattca gataacaaac
    12001 atcagacagt agatgattat ccatacggcg gtggagcagg tatgctgctc aaagtccagc
    12061 ccatctatga taacatccaa gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa
    12121 ttcttcttga cccagctggt aaacgattcg atcagaaaat ggcagaagaa ttttcacaag
    12181 aagaacactt agtattcatt tgtggtcatt atgagggata tgatgaacgt atccgcacat
    12241 tagtgacaga tgaagtttcc ttaggagatt atgtccttac tgggggagaa ttaggtgcga
    12301 tggtcatgat cgatgcaaca gttcggcttt tgccagatgt gttagggaat cagacttcag
    12361 ctcaaacgga ttcttattca accggtttat tggaacatcc ccaatatact cgcccggcag
    12421 aatataaagg gatgaaagta ccagaagtat tgacaaatgg aaatcataaa ttgattgaag
    12481 aatggcaatt aaaagaatca ctaagaagga cctatcaacg tcggcctgat cttttggaaa
    12541 cacttgaatg gacacctcaa atgacgaaat ttttagaaga aatcaagaaa gaagaacaag
    12601 aaaaaacagc agatgaagcc aagtgacttt ttctaaaatc ttctttacag taggttgata
    12661 atatgttagt attttatggt gagtgcaaaa gcacttaact attacgatat tccgctgtga
    12721 gaaaagctca taagaatatt tggaataagg agaagaaaac catgaatcca ttaatcgaag
    12781 aattaacaaa agaacaatta cgttctgaca tcccagcgtt ccgccctggt gacactgtgc
    12841 gtgttcacgc aaaagttgtt gaaggtactc gtgaacgtat ccagttattt gaaggtgttg
    12901 ttatcaaacg ccgcggtgct ggaatcagcg aaacttatac agtacgtaaa gtttctaacg
    12961 gagtgggcgt tgaacgtaca ttcccattgc atacaccacg tgttgcaaaa atcgaagtag
    13021 ttcgctacgg taaagtacgt cgtgcaaaat tgtactacct acgtgcatta cacggaaaag
    13081 ctgctcgtat caaagaaatc agaagataaa cacggaaaac ttccttggaa atctgaaatt
    13141 tgtgaaaagt ccttgtatat caagggcttt ttcttttttc tctatcacag ttttaagcca
    13201 tttttggctg ttttggacca tttttcaatc atattccctt aaaaattgtc ctagattgtc
    13261 cgacattgac tatcagtgtc gtcaaaatag ggcaaaattt agtagtcagc ttgacgacaa
    13321 atataatacg aaaaatacca aaacatttac cgaatttagc aacttttgaa cccaagtttc
    13381 tcaaagggtc agctattagc aaaaaagaca aaacatgtac ttttctacta aaaagttgat
    13441 gtgataggct tctatctaaa taactattag gagtttttat cgtgaagcaa aatgatggac
    13501 gtatcatttg gaaaaatcaa agtgagttaa aactgatttt aacaattaat gaattcatcg
    13561 aaaaacacgg aattacatct agccgtcaat accagaaaaa gctatcagaa aatccaaatt
    13621 ctgcaccaag tatgtggttc attaacaaaa aatatggatc atgggagaat ttattgatta
    13681 gtataggacg agaaaatact gggtatggaa aatgggctag aatgtcagaa caagaattat
    13741 tggaaatagt agaagccttt attaagtgcg agaagataac ctctcaacga atgtacgaac
    13801 aaaaatcagt agggaagaat attccttcac ttagtaccat taaaaagatg ttaggagata
    13861 tacgtccact ttttaaagaa aaaaatgatg gatctcgatt tactgatttc gaactgctgt
    13921 tagaactaaa aaatgaaata atccgattaa aactacagga tgatttatca atgacaaagt
    13981 ttcgaaaact agttcaatcc ccaaaactac catcagttga tacaattatg aaaagaacga
    14041 acaaaaattg ggaggaattg atggcagaga ttggatttga ttatcgaaga atcaaaattt
    14101 ataagcagag aaacaaccta tccaagacaa agaaaactaa atagtatcac tctaaatcag
    14161 acgttcaaaa ttaaaatttg gacgtctttt ttattaccca aaaacgaaag gagatttatt
    14221 ttatgaaaaa gccaagattt aagaattggc gtttgctcgc aacactgagt ctattatgcc
    14281 aaacaattgg tggatcgctt ggcccaacga ttgcctttgc tgatgaaatt actcatccac
    14341 aaacggtaac tgtggaattg gatttggctc accagtatgc tgtcgaaggt acatttagcg
    14401 atggtcgtcc catgtcagaa gttaccgttc cgcactatgc agtttacaat ggtgtgaagc
    14461 aagatatttt ctgtattgag ccaggggtgc cgatttacaa tgagttcact cctggttatg
    14521 agaaaaatcc attgcctgat atgtcggaga aagcgaaatt agtttccgtt ttatggaagg
    14581 aagctggtac ggatgtggat acacatattg tggcccagaa gatgatttgg caagaagtta
    14641 atggctacac gcttcactca attaaacgtt ctgatggtag tgcagtaaat atcgcagcca
    14701 ttgagtcaaa aatcaatcaa gccattgcgg attatcaaaa gaaaccaagc ttccataact
    14761 ccacagtgaa aaccgtgtta ggtcaatcga ctactgtgac agatacgaac ggcttgaatt
    14821 tatcggagtt tgatgaagtt gtcgagaata tcgcaaatat tgattatcgt gtgaacggca
    14881 atcaactagt gattactcca aatgccaatt caaaagagag tggtgaatta accctaaaga
    14941 agtcagctaa tacaggaaca ccggtagctt ataaaatggc tggtcaacaa actttgatgg
    15001 cgggggcaat tgataagccc aatacctaca caatcaaaat tgatgtggaa actgagggtt
    15061 ctttgaagat taaaaaagtc gataaagaaa caggaaatgt tgtaccggga accgttttcc
    15121 atttagactt tggaaaaaca ttacctgcaa aagacgtgac caccgataaa gaaggcattg
    15181 cgacattgga tgagattcct catggcgcga aagtaaccat tactgaaaaa tcagtgccag
    15241 ctccttatac gattgacact acaccaatca ccgcaaccat taaatctggt gagactattt
    15301 ctgtgacttc aaaaaatact cgcgaaaaag gtcaaatcat tttgaataaa atgggggtgg
    15361 aaacaggaac tgatctttgg aacgacaaat actcattagc cggaaatacg tttgccattc
    15421 gcaaagacag tccaaccggt gaaattgtcc aagaaatgac cacggatgaa aaaggtcatg
    15481 cggaaacacc aaaagagatt gccaatgcgt tggaattggg aacctattat gtgaccgaaa
    15541 ccaaagctag taatggcttt gtgaatacct ttaaaccagt aaaagtcgaa ttgaactatg
    15601 tcaatcaaac cgtggctctt gttaccagta acgtaaaagg gcaaaaccaa gaaatcactg
    15661 gtgaaaccac tttgacaaaa gaagacaaag ataccggtaa tgaaactcaa ggtaaagctg
    15721 agtttaaagg agctgaatat actctcttta ctgcaaaaga tggtcaagcg gtcaaatgga
    15781 gtgaggcttt taaaccagag ttagtgaagg gaacgaaagc ttctgatgaa acggtgactt
    15841 tgactttaga tgaaaagaat caagttgctg ttaaacactt agcgattaat gagtattact
    15901 ggcaagaaac caaagcacct gaaggatata ccttggatga aacaaagtac cctgtttcca
    15961 tcaaaaaggt ggatgataac gaaaaaaatg ccgtgattac ccgagatgtt acggcaaaag
    16021 aacaagtcat tcgctttggc tttgatttct ttaaatttgc tggatcagct gctgggactg
    16081 ccgaaactgg cttcaatgat ctgaccttta aagtatcgcc attggaagga accagtgaga
    16141 ttacaggtgc cgaagatgaa gcaattacag cttataacga gcaactaggt tttgatggct
    16201 atggcaagtt tgaaaatctt ccttatgggg attatttact tgaagaagta gaggctccag
    16261 aaggatttca aaaaattacg ccattagaaa tccgttctac ttttaaagaa aataaagcgg
    16321 attacactaa gagtgaatac atttttacga ttaccgaaaa aggacaaaaa caaccaatta
    16381 aaacggtgac cgttccttac gagaaactga cgaataaagc attttctgtt agcttgaatc
    16441 gtttgatgct ctatgattta cctgaagaag aagatagctt aacttctctt gggacttgga
    16501 aagacggagg caaagaattg acagaccttg attctaccga gctagttgat aaattgagct
    16561 ataacttgca tgaaatcaaa gaagactggt atgtggtagc gcaagccatt gatgtggaag
    16621 cgacaaaagc tgcccaagaa aaagatgaaa aagccaaacc agtggtaatt gccgaaacaa
    16681 ccgcaacgtt ggcgaataaa gagaaaacag gaacttggaa aattttgcat aaattaaccg
    16741 cagaacaagt tttggataaa accatcgtct tattcaacta tgtgtatgaa aacaagaaac
    16801 cctatgaagc aggtgatgat ccagtagcga aagatgctag cttgaacaat caagcccaaa
    16861 ctgtcaattg tacggtggaa cgccatgttt ccatccaaac aaaagcccac ctagaagatg
    16921 gttcgcaaac ctttactcat ggggatgtgg tggatatgtt cgatgatgtg tcgattaccc
    16981 atgatgtact ggatggctca aaagaagctt ttgaaacaat tctgtatgca ttacttccgg
    17041 ataatacgac caaagaaatt tggaaatctg gcaaaattga ttatgaagtg aatgacaaag
    17101 aattcactaa aaccgtactt gcggaaaaag tggacacaag taaatatcca gaaggtacaa
    17161 gttttacctt caaagaaatt aactatggca aagacggaaa catcaatggg aaacacaatg
    17221 aggatctaaa agaaaaaact caaactttaa cacctaaaaa agttccgaca acaccaagtg
    17281 caccagaaca accggaaata ccaactgttc caagtgactc tcaagaatct agtcctacag
    17341 taaagacatt cccacaaaca ggggagaaaa attctaatgt tctgctgttt attgggttta
    17401 ccttgatctt tgcgactgct gggtattatt tctggaatcg ccgaaactaa ggtgatgtga
    17461 tgaaacaact aaataggaaa aaccaacgtg cgcgaccgcc tcctaaaaaa agtggtcgcg
    17521 ctatttttgt atccaaaact aaaaatgaaa agaggaaaag aagatggaat tgaaatttgt
    17581 tgtgccagat atggccgaaa cctttggaaa gataaggtat gccggcgaag gcgaagtttt
    17641 aactgaagga tatgggcgga atactacagt aattggtcgt agttatcatt tgtattccag
    17701 taagcaacga gccgatgata ttgaagtggt ggtagctgcg gaagccggcg aaaaggattt
    17761 tgatcaagat caaccactaa aagccgtgaa tccccatttg gttgccaaag gctatgagat
    17821 tgagaatcgt gggtttaccg actacgtgtt gtatgtcgat gatttagtga aagcatagga
    17881 ggaaaagaag atgagattaa cagaaggtat tgttgtagat tcaggactaa cgtttgggaa
    17941 attacgattt tccgcattac gccgagaagt acggaagcaa aatgaggatg gaacggttag
    18001 taacgaggta aaagaacgga cttataattt gaaatcctct gcgcaaggtc gaatgatcca
    18061 agttagtatc ccagcaaatg tacccttacg cgagtttgcc tatgacgcag aggtagagtt
    18121 ggtcaatcca atcatggata cggtcgccaa ttatgttttc cgagaaggaa ctactgtcaa
    18181 ttggttcatt aaggccgatg atttagtctt gaaacgacaa ccagatcagg gaaattctac
    18241 aaaccaaaat gaaggaaaga aataggtgaa gcgtatggaa attaatgttg aacatatttt
    18301 agattgtctc gatcaatatg gaaaaggtga gctaacggag gaacaactca ctaaagcatt
    18361 aacctatgat gaaaaaatgt ttctgattat gcatcaaggg ttactggaag taggtaacga
    18421 tgtcgaagaa gattttgatg tactgaattg gttaggggaa gaagagtcct tctttatggt
    18481 tatcgaagta aatgaaagtc tatgtcgaga agccgaaacc gtattggaag aaattggtgt
    18541 ggaaatgccg gatgccattg aagttttttt aaagcaacta gtggaaacga aacaactccc
    18601 tatagcagta aatgactagc ataactgctt gaaattggat caatgaaatc ctatgaagct
    18661 tttttcgatt ggaggtggaa accataaaaa tgtacaaagg gcatcgtata cgggcaggag
    18721 atcagcactt ggtttatcac tttgttcttg gctggctact cgctctgttc atcggttgga
    18781 tgagcgtctt ttattttcaa gagcttagac aatttgatat ttctaagcta tcactttcta
    18841 ctatagaaat cgttcgttct ataaaagatt taatctattt gctaggaagt ctcgttcttt
    18901 caggaagcac gatgttgctt tatatacact tttttcagga tcattggcgc agtttgtggc
    18961 atcgacaaaa gctagcccgg atgattctag aaaatcattg gtacgaagta aaacaaactc
    19021 agagtgaagg atttttcaaa gacctcaata gtagtcgaac caaagagaca atcagttact
    19081 tccccaaaat ctattaccgt atgaaggatg gtttactttc tattcgcgtt caaatttcac
    19141 tgggaaaata tcaagatcag cttttaaagc tggaaaagaa gttagaaagt ggtctatatt
    19201 gtgaactagt agaaaaggaa ctcaaagact cctatgtgga gtacacttta ctgtatgata
    19261 taattgccaa tcgaattggg atagacgaag tagtggcaga aagtggggct ttgcgattga
    19321 tgaaaaatca agtatgggct tatgattctt tacctcatat gttaatcgct ggcggcacag
    19381 gtggtgggaa gacttacttt ttactcacta tcatcgaggc tttattaaaa tctgatgccg
    19441 agctttttgt tcttgatccc aaaaatgcgg acttagccga tttaggtacg gtaatgcctc
    19501 atgtctattc ccaaaaggag gaaatttctg cttgtgtgga agatttctat gagcgcatga
    19561 tgactcgtag caaggcaatg aaagaaatgc ccaactacaa aacaggagag aattatgcgt
    19621 ttcttggact tccaccaaac tttttaatct ttgatgaata cgtggtttat atggaaatgt
    19681 taacgacgaa ggaaagtgcg gtgattttga ataagctcaa acaaatcgtg atgttaggtc
    19741 gtcaatctgg tttctttctg attctagctt gtcaaagacc ggatgcgaaa tatttaggag
    19801 acgggattcg cgatcaattt aatttccggg tggctttggg tcgtatgagt gaactgggat
    19861 attccatgat gtttggcgag gttgataaaa aattctttat gaagcgtatc aaaggtcgag
    19921 gctatgtaga tacgggaggg agtgtgatta gtgagtttta tacgccactt gtaccaaaag
    19981 gatatgattt cttaagggaa attagcgaca ttggtggatt aaacgttaat acggaaggat
    20041 aaaataatag tatgtagcct aggagtgtca agaatcctgg gcttttttta cgaggtgatt
    20101 tatgacattt ttagatttat tcgctgggat tggtggcttt tgcttaggta tggaacaagc
    20161 gggtcaccag tgtatcggct tttgtgaaat tgatgatttt gctcgccaga gttataaggc
    20221 aatccatgat acaagtaagg aggtggaaat gcatgacatc acaagtgtat cagacgagtt
    20281 tattcaatct ctcggaccag tggatatcct ttgcggtgga tttccgtgcc aagctttttc
    20341 aattgcggga aagcggcaag gattttccga tactcgaggt actttattct ttgaaatcgc
    20401 tcggttcgcc gctattctcc aacctaagtt tttattcctt gagaacgtcc ggggattact
    20461 caatcacgaa ggaggggcta cgttcgagac gatcctccga acgctggatg gattggggta
    20521 tgatgtggaa tggcaagtgc ttaactcaaa ggcctacgtt ccccaaaacc gtgagcggat
    20581 cttccttatc ggacattctc gagacgcatg taccgaacaa gtatttccta tcattggatc
    20641 gtctccaaca tctgatcaaa acatcagaaa cttattaaat atcaaccctt ccaatcgagg
    20701 aatgggggga caagtctatg ggtcagatga cgtagcgcct accttgaccg gtgatgaagg
    20761 aatcaaaatc gcattgccgg tagatgatgg aatttctgta gcgggtatgt tactgggaaa
    20821 ttttgaacaa ggcaatcggg tttatgagat aactggaaca gcgcctactt tgtcaacgaa
    20881 acaaggcgga acgaagatca tgcttcggaa aaacgaaaca gaatatcaag aggtgaagcc
    20941 agggaacagt gtgaacctgg cttttcctaa ttccacaagt cgtcgaggcc gtctgggaaa
    21001 acaaagtgtg cataccttat taacaggaga ccaacaagca gtcgtcacgg atcagtatca
    21061 aattcgaaag ttaacaccta gggagtgctg gcggcttcag ggctttccgg actgggcttt
    21121 tgatcgagct tctcaagtca attcagatag tcagttgtat aagcaggctg gaaattctgt
    21181 aacagttccg gtcatttttg atattgctag aagattaaag gaggtaaaaa cagatgattt
    21241 atgatgagtt gattggggaa tctactgggt gattggcaag attcagtcag atccggaatt
    21301 ggaagaagaa ctgtaccggc tcaattttga tattcgcaaa aacggggtga aagtccctga
    21361 tgatccgtat gtaattgatg aggaaacgga tgctcgaatg gagctgaatc aagtcatcag
    21421 tgaattggaa cgaattgcgg actttgctaa agaacctgat atccgccaat acttgtttga
    21481 gataaaagca gagttggaaa ttgagggtat taccgcggag taacggccaa ataaaccact
    21541 gataggcact gaccgcgggg gatttgcgaa gcagaaatcc tccgtggtgc tgtgcctgtt
    21601 tatggacggc gttagccggc catgatgtct caccccccgt atctaacagg ggggtacaaa
    21661 aacacaaaaa ataagcaagc aacgataagg aatggctgtc ctatcaagga taataagcaa
    21721 tttgtgtaga tgttaactga tttgaaaaag ttaacacctt aaatttggag gtgagaactt
    21781 ggcacaaagg aatttagatt atcggctatt aaaagaccgg cgtaatgaat atggcgtttc
    21841 acaaaataaa ttagctacga cttgtggact tagtcgcccg tacttaaatc agatagaaaa
    21901 tggtggcgta accgcatcga caaaaaccat gaggaaaatt tttgaccaac tggaaagttt
    21961 caatcccgag ttacctttaa cgttactgtt tgactatgta aggattcgct ttcccacaac
    22021 ggatgcgagg aaaatcattc aagagattct ccatttgaaa tttgattata tgctccacga
    22081 agattacgcc ttttactcct atcaagaaca atatgttatg ggagatattg tggtgatgtt
    22141 gtcacatgaa gaagataaag gcgtcctttt agaattaaag ggtcgtggtt gtcggcagtt
    22201 tgaaactttt ttactcgccc aaaagcgtag ctggtatgac tttttcgaag attgtctaaa
    22261 agccggtggc gtgatgaaac gcttagacct ggcaatcaat gatcgagttg gcctgttaga
    22321 tattcctgat ttaacgaaaa aatgtcagaa ggaagaatgt atctccttgt ttcgtacctt
    22381 caaaagctat cgttccgggg aactgttgaa acctgatgat aaagatggta tgggcaatac
    22441 tttgtatatt ggcagtctta agagtgaggt ctatttctgt ttgtacgaaa aagactatga
    22501 gcaatatatc aagttaggga ttcctttaga ccagaccgaa acgaaaaatc gttttgaaat
    22561 ccgactgaaa aatgatcgag cttatcatgc aattcaagat ttgttaaaag gtcgcagtat
    22621 tgaaagtacc acattttcca ttattaaccg gtacttgcga tttgcggata aggtggaagg
    22681 caaaaggcga actaactggc ccttgaatga acaatggggg cgcttcattg gacggaatca
    22741 gaaggaaatt caattaactt ctgaaccgaa gccttatacc attgaacgaa cgttgaactg
    22801 gcttggacga caagtcgccc ctacgtggaa gatggccaag gagttggatc ggttgaatca
    22861 gacaacgtac attcaggata tggtaaataa tactcgacta tcagaccggc acaaaaagat
    22921 tttggagcaa caaagtatgg caattgaaaa tttgattata tgaaaagagg aatcgtgatg
    22981 gaaattgtga aagatatttt attggtgttt ggtggcagta tgcttggtgt tactgtgatg
    23041 tgcttgatgc atgcaagtgc agcggcggac cgagcaatgg aaaagaaagg aaagtgatga
    23101 aatgaatttc ggtcaaaatt t
//
LOCUS       DACCVH010000041        22661 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.041, whole genome shotgun sequence.
ACCESSION   DACCVH010000041 DACCVH010000000
VERSION     DACCVH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.041"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1104
                     /locus_tag="IVV98_001628"
     CDS             <1..1104
                     /locus_tag="IVV98_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7807288.1"
                     /translation="TNNDIDGLNAELWLDMDKYGRAYEIIYRDSDDTDYVDLANVFET
                     FVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKSITYDETTLTAIELKNP
                     QDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDTANYMTDLNDALLVISG
                     DIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIYKQYDVNGVEAYKYRVR
                     KDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQRLFKKGLMRRYRLLFSL
                     KSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELSQETILGLASFVPDVQA
                     ELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            1109..2035
                     /locus_tag="IVV98_001629"
     CDS             1109..2035
                     /locus_tag="IVV98_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP7807289.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            2162..2764
                     /locus_tag="IVV98_001630"
     CDS             2162..2764
                     /locus_tag="IVV98_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP7807290.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            2777..3700
                     /locus_tag="IVV98_001631"
     CDS             2777..3700
                     /locus_tag="IVV98_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP7807291.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            3718..3981
                     /locus_tag="IVV98_001632"
     CDS             3718..3981
                     /locus_tag="IVV98_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807292.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            3993..4322
                     /locus_tag="IVV98_001633"
     CDS             3993..4322
                     /locus_tag="IVV98_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HAP7807293.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            4319..4645
                     /locus_tag="IVV98_001634"
     CDS             4319..4645
                     /locus_tag="IVV98_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807294.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            4629..4967
                     /locus_tag="IVV98_001635"
     CDS             4629..4967
                     /locus_tag="IVV98_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP7807295.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            4967..5359
                     /locus_tag="IVV98_001636"
     CDS             4967..5359
                     /locus_tag="IVV98_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HAP7807296.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            5370..5882
                     /locus_tag="IVV98_001637"
     CDS             5370..5882
                     /locus_tag="IVV98_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HAP7807297.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            5928..6296
                     /locus_tag="IVV98_001638"
     CDS             5928..6296
                     /locus_tag="IVV98_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807298.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            6350..6637
                     /locus_tag="IVV98_001639"
     CDS             6350..6637
                     /locus_tag="IVV98_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807299.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            6654..9773
                     /locus_tag="IVV98_001640"
     CDS             6654..9773
                     /locus_tag="IVV98_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP7807300.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            9806..10573
                     /locus_tag="IVV98_001641"
     CDS             9806..10573
                     /locus_tag="IVV98_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7807301.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            10570..13401
                     /locus_tag="IVV98_001642"
     CDS             10570..13401
                     /locus_tag="IVV98_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP7807302.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            13376..15133
                     /locus_tag="IVV98_001643"
     CDS             13376..15133
                     /locus_tag="IVV98_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAP7807303.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            15150..15932
                     /locus_tag="IVV98_001644"
     CDS             15150..15932
                     /locus_tag="IVV98_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807304.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            15932..18118
                     /locus_tag="IVV98_001645"
     CDS             15932..18118
                     /locus_tag="IVV98_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAP7807305.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAI
                     DKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFV
                     DRDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSA
                     YSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWG
                     LTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKD
                     SNNPNDYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVY
                     TLTKDNSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGM
                     LTGPSGTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            18121..18567
                     /locus_tag="IVV98_001646"
     CDS             18121..18567
                     /locus_tag="IVV98_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807306.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            18569..18706
                     /locus_tag="IVV98_001647"
     CDS             18569..18706
                     /locus_tag="IVV98_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP7807307.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            18743..19036
                     /locus_tag="IVV98_001648"
     CDS             18743..19036
                     /locus_tag="IVV98_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807308.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            19059..19256
                     /locus_tag="IVV98_001649"
     CDS             19059..19256
                     /locus_tag="IVV98_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP7807309.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            19267..20286
                     /locus_tag="IVV98_001650"
     CDS             19267..20286
                     /locus_tag="IVV98_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7807310.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            20543..21190
                     /locus_tag="IVV98_001651"
     CDS             20543..21190
                     /locus_tag="IVV98_001651"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7807311.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            21473..21546
                     /locus_tag="IVV98_001652"
     tRNA            21473..21546
                     /locus_tag="IVV98_001652"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21507..21509,aa:Ile,seq:cat)
     gene            22092..>22661
                     /locus_tag="IVV98_001653"
     CDS             22092..>22661
                     /locus_tag="IVV98_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP7807312.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         7898 a         3661 c         4872 g         6230 t
ORIGIN      
        1 actaataatg acatagatgg gttaaatgct gaactctggc ttgatatgga taagtatggg
       61 agagcctatg agattatcta tcgagattca gatgatacag attatgttga tttggctaat
      121 gtatttgaaa cgtttgttgt atatgatact acagtaaaac gagagcctat tttggctgta
      181 cggtatccta agacaagatt caacaaggat gctgataaac agtacattca accaatcgta
      241 tacacaaaag aaaaaagtat cacttatgat gagacgacac taacagcaat tgagttaaag
      301 aatccccagg atgaaccgca tgaatataaa gaggtaccta ttacagagta ttctcctaat
      361 cgttttcgga tgggcttgta tgaagatgta ctatctttga ttgatctata cgatgcaggg
      421 cagtctgata ccgccaatta tatgactgat ctaaacgatg ctcttctagt tattagtggt
      481 gatattgaag cagcaggact atccacagag gacgccatca agcagaaaga agcgaatatg
      541 cttttgcttg agtctggaac tgatgtgaac ggtaataaaa caagtgtgac tgcaggatat
      601 atttacaaac aatatgatgt gaacggtgta gaagcataca aatacagagt acgcaaggat
      661 attcacgaaa tatccatggt tcctgatctt actgatgaca atttttccgg agtgcaatcg
      721 ggagaagcaa tgaaatataa attatttgga tttgaacaaa tgacggcaac aaagcaaagg
      781 ctattcaaaa aaggccttat gcggcgttat cgtcttttat ttagcctaaa atcaagtatt
      841 tctgaaatgg ataactccga tttgaaaggc ttacgtgtaa tatttacgcc taatctacct
      901 aaagccattc tggaagagtt gaaatctttg gttgatgctg gagctgaact cagtcaagag
      961 acgatcttag gactcgcttc ttttgttcca gatgtacagg cagagttgaa acgagtaaat
     1021 aaagaaacgc aaaagcagat tggcattttt gattcagatg gtgaagaagt aattaacaac
     1081 aaaaaagatg aaacaggggg gtgattaaat gaactcccaa gaatattgga tcaaacggga
     1141 aaaggaatgg caaaagcaac aaattaaaga tgataaaaag cgcatggcag aaattaaaag
     1201 tcgcatgcaa tacgcacaag atgcgataca aaaagaaata gacgcgcagt gggacagttt
     1261 ctccaatggc cagaaaatca ctcgtagcga agcgatgaag cgtgctagtg aaatggatgt
     1321 caaagcattc gctcgcaaag caaagaagta tgtcaaagag aaagattttt ctcctacagc
     1381 aaaccaagaa ttaaagctat acaatcttac gatgcgtgta aatagattag agctcttaaa
     1441 agctaatatc gggcttgaat tgatttcact gtttaatgaa ttggataagt acttttcgaa
     1501 tgaattaaca aaagctggtt tagctgaatt gaagagacaa gccggtattt tagaaatgac
     1561 tattgcttca agtggatatg caaagctgat agaactagta ataaacagct cctttttgag
     1621 tgatgacgtg tcttttagtg atcgcttatg gatgtatcaa tctgaattga aatcagaatt
     1681 agataggttg ttagtcagaa gtataacgat ggggaaaaat cccaagcaac ttgcatctaa
     1741 attggcagaa tatttaacag ctgaaggacg agaaaacact aagttcaaca ctcaacgttt
     1801 gatggtgact gaaacgacta gagttcaggt agggattcaa gaacgaagtt atagagatgc
     1861 aggcattacc cagtacatct atatagcaga accaacggcg tgcaaactat gtataccgtt
     1921 aaataatcaa gtttttgatg ttgccgatat gcagccagga agtaacgctc ctaatatgca
     1981 tccattttgt cgatgcagta cagcacctta tatagaacga atatcaagcc gttaacacaa
     2041 attaacggct ttttattgtg ccttcttaca gcttacaggc gttaaagaga aagctatttt
     2101 cggctgaccg gcgtaactgg tcaaatttat cgggtagcgg cgtaaccgtg gaggattaat
     2161 catgaaaaaa cgtttattta tgccaatgaa cttacaattt ttttctgaac caggagatgg
     2221 tggatctggt gatgagggac aacaaggaaa cctaccagct ggctcacaag agacaccgcc
     2281 cgaagcaaaa gaagaaaaca atactggcaa aacattttct cgtgatgaag tagcgaaaat
     2341 gatcgctgct gagacgaata aagcaaaagc agcgtgggaa aaagaactag cagcaaaaaa
     2401 agaagaagct aaaaagctgg caaaaatgaa tgcggaagaa aaactacagc atgagttgga
     2461 gcaaaaagaa gctgaaatcg ctgaattaaa gcgtggacag gcactatctg aaatgacgaa
     2521 agaagcttct aaaatgctga cagatgcaaa tttaccacac gatgatgatt tacttggtct
     2581 gattgtttct gatgatgcag atgccacaaa acaagctgta gcagtcatca ctaactttgc
     2641 ttctttgatt aagagagaaa acgcaagaca aacaccacca aatgaaggtg gacaatttac
     2701 agcatcgaaa aatactaaag aaacagtggc taaactagct gctaaaaatc gaattatcaa
     2761 ataggaggaa aacttaatga aaaagaaaca acttttacca atgaacttgc aaatgtttgc
     2821 tcaaacatgg gatccagata atgtcttggt atatgaaacg aaagagggaa aaattcctga
     2881 taaatataat acgctcattt tgagtgaagt tatggaaaat tctaagatca tgcagttagc
     2941 aaaatacgaa gaaatgactg acaaagaaaa gaaatttgaa tactttgcag aaggaccagg
     3001 cgcatactgg gtgggtgaag gtgaaaaaat taaaacgtct aaacctaaat ggatgcaagc
     3061 tacgatgact gcaaaaaaac tcggtgtcat tcttccggtt tctcgtgaat atttaaatta
     3121 taaattatca gatttctttg aggagatgca gccaaaaatt gctgaagctt tctataaaaa
     3181 atttgatgca gctgccttat taaataaaga aaacccattt cctcagtcac tagacggatc
     3241 agttattagt gcggggaatg tggttgaagg cggattgact tatgataata tcctagcctt
     3301 agaagacaag ttagcagaaa atgaattcga acctaatgcg tttatttcaa accgaaaaaa
     3361 tcgtacagaa ttacgttctg cagctcaaac agtcgggtca aatgttgagt ttatttatga
     3421 tcgctctact aatacaattg acggattacc agtagtagac cttaagtctt tagataaagg
     3481 aacactttac gctggagact ttaattacat gttttatggg atcccatata atatttcatt
     3541 taagatttct gaagaagccc aattgtctac tttaactaat gaagatggaa ccccagttaa
     3601 cttgtttgag caagaactga ttgctttgcg tgcaacaatg gatgttggat ttatgattgt
     3661 aaaagatgaa gcatttggga agatttcccc aaaagcgtaa cgcctgctac cggtattgtg
     3721 ccaaatcaaa agacatggac cggtaaagta ggcgatacta aaacatttac tatttcagct
     3781 gtgcctgcag atgctagcga tgcagctgct gttgttgcag ctactacagc aacttcaagt
     3841 gatggagcta tcgcaacagt gaccaaaaat gaaaatggtg gttttgatgg aacgattgca
     3901 gcagaagggt cagcaacatt cacatttact tctggagaat tcactacttc aatcaatgtg
     3961 acaggtcaac ctgctagtta ggaagtaaaa atatgatgat tgcagatgat attaaaaaac
     4021 ttcttaaagg aacaatagat gaaaagcttg aagttattga gcgaagaacg aatgagcgta
     4081 tgaaaacctt gttaaatacg caagaagttc ctaaagaatt tgaaacagtt gtatatgaag
     4141 tatcgttgaa aagattcaat agaattggtc aagaaggtat gcagtcatat tctcaagaag
     4201 gtttatctat ggcttttcct gactcggatt tttcagagta tcaaaatgag attgatgaat
     4261 ttaagcgtaa agatcaggaa gagttgtaca agccaaagcg agggaggttt aaatttgtat
     4321 gagatttaca gatgaaatta tatttgttaa acgttcatct gactctaaat atgatccaga
     4381 tctcggtgag tgggttgaag gcaaaccaga aagaacaaga acagaggcaa acgtgacaga
     4441 tattggcact gatagaagtg tgactatttt tggtagtgtg gaagaagggg cgaaggtcat
     4501 taggacgcag cctctttttt ctatccctac atttgactat atcgagattg aaggaaagac
     4561 ttggcaacaa aaaacagcta gaaatccagc atatagaaat agtttaattg tgcaagaggt
     4621 ggttcttgat gaaggcacaa cttgaatata aaggaatcga tcagctgatg cgacatctga
     4681 aaaaagcagc aacgcttaat gacgttcaaa aagtcgtgaa aagtaatact gctgaaatga
     4741 ctgaacgaat gcaaaaaggt gcgccagtgg atacaggtta cttacgaaga tcaataaaca
     4801 tgaatctttt agaagctggt ttaactggta ttgtaggacc gacagcagat tatgcacctt
     4861 atgtagaata tggcactcga tttatgtcgg cacagcctta tgttagacca gcgtttaatt
     4921 accaaaaagt caaatttatg gctgaaatga aagccttggt gaaatgatga ttaagacaag
     4981 agatcaatca atttttgatg aactttttaa aatatcccaa aacaaacttg gatataaaac
     5041 atacgattac aaaactttag aggatgttgg ttatcctttt gtggaatttg agaacactca
     5101 gacaatccat gaagtaaata aaactgacat taaagggtct gtgattgtgg ttttatccgt
     5161 ttggggatta cagaagaaac gaaagcagtt gtcagatatg gcatctgctc tttttaatga
     5221 agctagattg atagaagcca cagaaggcta ttattgggct ttaaattatc aagcaagtgg
     5281 aattcaagtg atggacgaca caacaacgaa tacaccgcta aaacgggcgg ttgtcacact
     5341 tgaatttaga attagatagg aggaagaaca tggaagcatt aaaaggtatt gatgtcattt
     5401 tgctttatcg cttattgaaa aaagaaactc aggaagccgc ttggaaaatg gcatttcaaa
     5461 cagaacacga aaatggttta tcaagagatt cagactctac agtgacaaaa gatggaaacg
     5521 ttcaaagttt aagcccggtt gaatatgatt tttcggctac ttcaatagtt gctaaaggag
     5581 attctcatgt agatgaaatg aaacaagctt tattaaatgg ggatatcatt gaaatttggg
     5641 aaattaataa agcagaacag ggaacagatg ataatgcaaa taagtacaaa gctacttatt
     5701 accaagcata tgtgtctgaa tttactccat cggctgctgc agaggataac gttgaattaa
     5761 gtttatcatt tgcagtaaat ggtgttggtc aagatggtta tgcaaccttg acagaagatc
     5821 aagccgatgt tgttcaatat gcattcaaag ataccgtgaa agcaacttcg acaggagcat
     5881 aagagggctt agatgctctc ttttttattt taggaggatg aaaaacattg aaattaaaaa
     5941 ttaaaggtaa agaatattcg tttaaatttg gcactaaatt tgtacgtgaa ttagataaag
     6001 tgatgccttt cgtcgatgga aatatggaat ttggaatggg actctccgca aaagtcttac
     6061 cagagctacg ttcttataac gttaacacgt tatcacgagt tctggaaata gcaaatagaa
     6121 ctgaagatga atctattaca ttagatgaat tggatgatta catcgatgaa gttaaagaca
     6181 ttgaaaaatt gtttgatgaa gtcctaaaag aattggcgga gtcgaacgcg ggaaagttag
     6241 cggtccgaaa cctgaatcag aaattgaaag aagcggaaaa acaacaagtg gaatagattc
     6301 tgcactggca tacgaacaaa ttcttatcaa ttcttttcga tatttgggaa tgaccaatat
     6361 ctcagatatc gaaagaatga cgttatatga atacaacatt cgtatgactg cagcccagtt
     6421 atcttggctt gacaaagaaa agttgattca cgaattagcg tgggcaaatc agcaagtcca
     6481 agcggagaaa aaagtaggca aaaagacagt tcctgtatat cgatcctttg aagaattctt
     6541 caattatcaa aaaatcgaag attcaatcat gggagtttcc gaactttcaa aacaagataa
     6601 aaaattccaa agcttactaa ctaaagctaa ctcttgagga aaggaggaga atcatggaac
     6661 aattttctgt tgaagcctta ttaaaagcca cagatagtgg atttgtaaag acttttaaag
     6721 atgcacaaga tgctgttaaa acttttgaaa agaattcaaa tagtatgaca accgctgttg
     6781 gtaaagtgat gcaaggtact ggtgccgcaa tgacaaagta tattaccact cctcttatag
     6841 gagtaggcgt agcagctgct aaagttggtg gcgacttcga agcacaaatg agtcgtgtaa
     6901 aagctatatc aggagcaacc ggcgacacat tcgaacagat gaaacagcaa gcgattgatc
     6961 taggagcaaa aactgctttt agcgcaaaag aatcagctgc tggaatggaa aacttagctt
     7021 ctgctggatt tagcgcacaa gaaatcatga aagcaatgcc gggtctttta gacttagcag
     7081 ctgtatctgg aggggatgtg gctctagctt ctgaaaatac tgctactgct ttgagaggat
     7141 ttggtttaga agcaagtgaa gcaggacatg tcgctgatgt atttgctcgt gctgctgcgg
     7201 ataccaatgc tgaagttgga gacatgggag aagcattgaa gtatgttgct cctgtagcta
     7261 attcaatggg gatttctttg gaagaaactg cagcagctat tggtattatg agtgacgcag
     7321 gcattaaggg ttctcaagca ggtacaacgt tgcgaggagc attgtctagg ttagcaaggc
     7381 caacaaaggc tatgcaagat acaatggata atttaggtgt ttcgttttat gatgctgacg
     7441 gtaaaatgaa acctttaaaa actcaagtag aattacttaa aaaagctttt gaaggcctga
     7501 cgcctgaaca acaacaaaat gctttagtaa cactatatgg gcaagaatca ttatcaggga
     7561 tgatggcttt gattgataaa ggacctgatt cattgggcaa attaacaaaa tctctgaaag
     7621 attctgatgg tgcagctgac gatatggctc ggaccatgca agataatatg aattcttcca
     7681 tcgagcaaat gtttggagct tttgagtcag cagctattgt aattcaaaag attctagcac
     7741 catccatcaa aaaagtagca gatgccatat ccggcttagt agaaaaattt gtaagtgctc
     7801 cagaatcaac tcaaaaatta gtagtggcca taggagcaat tgtcgctgct ataggaccgt
     7861 taatttttat gattggttca gtaattatat ggatcaatag ggtgaaagta gcttttaaag
     7921 ctttaagtga aagttcaaaa ttgtttagtg gattaagtaa agcaatgggt cttcttacaa
     7981 atccggtttt tctggttata gctgcggtag cactactcgt tgtaggtttc atctatcttt
     8041 ggaatacgag tgaagatttt agaaactttt ggattggctt atgggaggga atcaagtctg
     8101 ctgtaagctc ggcagtagaa tggattcaga atgcatggaa atctacagga gaatggttta
     8161 acaatttatg gaagtccatt aaagaaggcg cagacaatgt ttggactaca gttcaagaag
     8221 cccctgggaa agcggcagat tggattaaaa acaaatggac tggaacaaaa gagttctttt
     8281 caaatttatg gtcaagtatt gcaaactctg cttcagagat ttggaatagt ttaaaagaag
     8341 gtgtcatatc agttattgat gatttagttt caagtgctgg tgaaaaatgg gaagggttta
     8401 aaaatactat atctactgca tggaaaacaa ttacaagtaa aatcaaatct ggttttgatt
     8461 ttatactaaa atatattggt ccatttgtaa gtagcttttc agatgtgttc tctaatatag
     8521 tgaaagcaat aacaagtata tttgctgagg ttaaaaacat aatagtaaat gcttgggaaa
     8581 tcattaagtc tttaatagct gcgccactac tgtttattat agatttaatt actggtgact
     8641 tcgaacaaat gaaagaggat ttagatctaa tctggaacac acttgtccaa tcagtggtaa
     8701 atatttggac atctgtaaaa aatatattta cggaatatat cggtgcaata gtaaatagtg
     8761 ccgttagttt atggactgga ttcatacaaa gtatttctaa tatttggaat gaagtagttt
     8821 atcaagcgac tatgatttgg attgatttga aactattttt tactaattta tggattgata
     8881 ttaaatacag tgcaattcaa atgtggataa atctaaaatt ctccataatt caaacttgga
     8941 ttgatacaaa atatggtgca attgaacttt ggaataatct aaaacaatgg tttttccaaa
     9001 cggttaataa tatcgtgcaa actcttataa aaagttggaa cagcttaaag caaggaacga
     9061 tagatttatt caacaataca gttcaaggtg ctaaagacat ttggacttca ttcaaatctt
     9121 ggattggtga tttaattact ggaaccaaag ataacatcat tcagggatgg gaaaacctaa
     9181 aacaaggtac tatagatact ttcaacaatt tagtaaatgg tgctcaagag gcatgggata
     9241 atttagtaaa tgctgttagt gacacggttg atagagtaac tggctggttt gataacttga
     9301 aaaatatcga tttactagca gccggaaaag ctatcatgga tagttttcta gaagggttac
     9361 aaaatgcatg gaaatctgtg caagattttg ttggaggtat tggtgattgg attcgtgaac
     9421 acaaaggacc tatccaatac gatagaaagc tattgattcc agctggtcag gctattatga
     9481 acggtctgaa taaaggtctg acaggaggat tcaatgacgt acagaatact gttggaagta
     9541 tggcagactt tatcgcggaa cttttcaatg caaattctga tgtagatata gctgcaaatt
     9601 tgaaaaatgc aaataaaaac attggtgcac aagttgaaca taaaataaat atgggtggct
     9661 ctactaaacc agctgtattt aaaatcaatc ttggaagaca atcgtttaga ttgtttatgg
     9721 acgatatttc acaagctatg ggcgaaggtg cagatattaa tctggaattt taggagggaa
     9781 tattttggat caacgagaaa ataaaatgta ctcattcaaa gatacaacca ttaatctcac
     9841 tagttctaaa cgattccttc cgacgtctgc catgatgtac gatggaatgt atttagaaga
     9901 tttgattgat ggttatcaaa cacttacggt ggaaggtaga gaaatgcttt ctgtagaagt
     9961 tgaacagcaa gagatacaaa ttggttcaat cattacaaat cagaaaatac cttcaagaac
    10021 actaaaaata acatataagc tggaagatag agatccagaa aaactacagt ttaaattcaa
    10081 agaactgttg aattatttat accggaatga agacgtggaa attaggtttc atgatgaatt
    10141 agattattat tactacggtc gctatacatc aactgatact gttccaggag actccaactc
    10201 gattatttcg agttttaatg tattctgtgc ggatccacta aagtatacga aagagtgtgt
    10261 tagtgatggc tatattggaa atccgataca gtttcctata acaccaagaa aaattgaagt
    10321 tactttatcc atgaataatt caatcaaaat tacaaacgga gaacaaaata tcacgataac
    10381 tgacgcggca ataaaaacag gagacgtgtt ggtttttgat ttttccgatg agcaggtaac
    10441 tgtaaacgga gaagattgta cttctatgat tgatttagaa agtgattttg agaactttta
    10501 tcttaagcaa ggtcagaaga taactagcaa taatgggaag cttaaaatat tctatagggg
    10561 ggcgacaatt tgagtgagac agtttatttc tttgatcact tgcaaaaact tattaaaaga
    10621 aaaaatacaa gaagtttgat tgaagtctcc caagaaaaag aaattagttc tgataagagt
    10681 gatctaatga aagatactct ttacgttacg acaaaatatg ataaagaaat agaggatgca
    10741 agatatatgg cgattcgtga aaacgagtcg tctttttcgt tgtatcgaat tactaaagtt
    10801 agcgacccat ttgaaacatt agagtttaca gggttaggat ttgcgacaaa tgaattagat
    10861 gcttacatca tcaaagatat taggccgagt gggcagccct taaaaaatgt tcttgatcga
    10921 ttgattgaat ttactgaagg aaattggcgc gttggtcacg tagaagcaat gttaccaaca
    10981 gtaactgcaa ctttttacta tgtctctgta aaagaagcgt tgaaagaatt gcaaacctta
    11041 ggtatggaat ttgtctttag gtgttctttg aattctgatg gaataaagga taaatggatc
    11101 gaagtatatg aacaaattgg cgaagaatcg aatacacgtt tcgtatatgg tagtaaagca
    11161 ttaacagttg taagagagat agatagaagc tcaatctcaa cttcaatgat aggtcgtggg
    11221 cgaggcgaag aggttggtga cggttacggt agaagaattg aattcactga tgttgaatgg
    11281 aaaaagtcga atggtgatcc tttagataag cctaaaggcc aaaattggct tgaagatccg
    11341 gaatcaactc aaaagtatgg gataccacaa aaagatggat caatgagaaa acgagaaacc
    11401 gtagtagtgt ttgatgatat agatgatcca acagatttac ttaaaaatac ttattcaacc
    11461 ttaatcgatt ctgctagacc gttagtacaa ttcaaagctg aagtcactgg aggagatgtg
    11521 ataggaaata cagtgactat tcacagatac gataaaggtt atcactataa aactcgtatt
    11581 tataaaacta cattcaatcg gcttaccggt caaacgaata tcgaactagg ggataattta
    11641 acacaagatg ttagaaaaca aacggcttct attgtcaata atattaatag tttagaatct
    11701 agcaaaatga cattttacga atcgacagag attggaaaat atcaagatga cattatgcga
    11761 ggtgcaggag ataatggcgg ttctatttat tgggtaaatg gaattgaagc tggtgttagt
    11821 gatagtagag aaatctatga aactgtttat atggatggac ctaacattcc tagatcacgc
    11881 ttttttatgg tccaaaataa ctcagggata tctttcaaac aatgtaaaaa aggtgagtgg
    11941 caaacaattc aagatgtaca caatggtgat agcacgaccg cttggacgtt ggatggaact
    12001 ttcaatgcta attttattcg cgcaggcatt ctgtctggta tcctcgtgca aggggtagct
    12061 ttaaaaacat ttgacgataa agatttccaa ttagtggcag aggggggaga actttctttt
    12121 gaaaaacaag tcaagtctac tggactagat gatgtacatg gagaacgctt gggctcaatt
    12181 gtatctactt atggttctaa agggattaac ggctttgctg tctggaaaga gccaaactat
    12241 attttttcca ttaatgctgg ggacggtggc gatcgaggga atcctatttt tcaaattcca
    12301 gcagatgtta ctgctgataa gcgcaaatat aatctttatg gtgacggcaa tttttcagaa
    12361 ggaaatataa ccatagatgg acggctagat gtaaaagaac tctatgttaa cggtacaaaa
    12421 attgacacta atggaggagg caattccgga gggaacgata acggttggaa cggacaatac
    12481 ccaccagaag taactactga tcgggataaa cgatattggc aaatttgggc aacggcaata
    12541 ggtgccggtt ttacacaaca agctgctgca gccttacttg gaaatgcaca aggagaatca
    12601 gatgctaatc caaccgctga tgagggcaat ggcgcaccag ggttcggtta tggtgtatgg
    12661 caatggaccg attcttctgg cgcaactagc ggacgtgtct acatgatcaa tttaatgaca
    12721 aaggctggca tcagtgatga tccagacaca atcacggcac agtttaaatt gttgatgtgg
    12781 catgcaccaa atggtcaatg gatcgcaact agcgcttatc cttacacatg gacacaattc
    12841 atgaatctga ccgatatcaa cacagcagca caagcattcg tggctaactt tgaacgtcca
    12901 cgtgatccac atccagaacg gacggcatgg tcacaagaat ggtatgacaa gttcaaagat
    12961 ttggaaattc ctgtatcaaa aggatatatg aagccgattg cggatccaat cacagtgacg
    13021 agcgaatttg gctggcgcac ttctccaatc acaggagcac aagaatttca taacggtatt
    13081 gaccttgtaa atggaaatcc taatacacct atttttgctt cagcggatgg cgaagtgatt
    13141 gttgcaggtg atgcaaatta ctttgactgg tatggaaatt ggacagtgat taaacacgct
    13201 gatggaatgt atacaggata cgcgcatcaa agccgagtag acgtctcaaa aggtcagaag
    13261 gtaactgctg gtcagcaaat tggactgatg gggacaacag gaccatccac tggagaacat
    13321 cttcattttc aatttatgga tgagttttat ccatcttctt caggtcattt ccacaatgca
    13381 agagactaca tcgatttcta aaggagggat agtcatggca gaaacgcagc ataaaatggt
    13441 cctatccacc accgaaccaa acaacggaat aaatttggtt cgaattcggc aaggggatgt
    13501 tttaacgcaa aagttcgttg ttgaagtggt ggaacatggc aaactaaaaa cattcgaggg
    13561 cctagtgccg ttttttatta atacaacaaa atttggcgaa aaccaacctg ttgaacaaaa
    13621 agtacaagaa tacagtccag cgcaagcaag gcttgtttac accttaagtg agcctgactg
    13681 gcaatggggt ggtgaaaaca ccgcacattt cagtttccga tcacttaatg gtgatggaac
    13741 ttggagtgaa caatttagca cacaggattt tacctatcga gtcatttctg gaatatctag
    13801 aagccagtta cgtgactctg gctatgtgtg gacatttgag gatttgctaa gaaaattcaa
    13861 agattacatg gatcagggca aaaatgactg ggagcagtgg ttagaagata atcgtgaaat
    13921 actggaaaat atcgatccag gtggtatgat cattaacatt ctgaatgaag ctaaaggcga
    13981 ctacgaatca ttagctgatc gtttaaacca aaaataccaa gtgccagtcg gcagctcaca
    14041 aattagagaa acaacacgct tttttgatta cgacacgatg aaatacgttg acctagtgcc
    14101 gcgcaatttg aatacggttg tcaacagtgt taataacagc aaatttaact tttctttcat
    14161 tacagacatt cacgcagata atcacaactt gcgtatagat ggcgtcggtt acaaagatgc
    14221 ttcttattta agacattggc gcgcaatccc tcaatttcaa aaattaggga acaaaacaga
    14281 tgtgatgatt tacggcggag acaatatcga cggcggactt ggttcactcg gcagcgatat
    14341 aggcattatt gatgaatgga gcgcgcgaca ttccatgtta ggcacgctca aacgcttcac
    14401 taacgcagcg gtagcaggac aagaaaaacc ggttattatc tgcaaaggga atcacgacgc
    14461 ttgtttcgac cccgcgtggc gcaagcgaaa gggaatgtta tgcaacgctg acttcgaaga
    14521 gtattggaac ggtttgtacg gtggcgtgtt gttcccagat aaaaacgcag caatttaccg
    14581 tttcgatact tgtgattttt atgaaggcgg cacaggcgac aagtacgtgg acggttacag
    14641 cgatacagcg ccgggagctt tcagtgccaa acaaattaac gctttcggag aatggttagt
    14701 gaacgttccg agaaactatc atgtggcgtt agtaggacat acgcctttag gtctcagcaa
    14761 gtttcccgtt cgcaatgaaa acatgattag cacgttgata gaagggttta aatctggtag
    14821 tccggtaact atcgattggt ctaaattagg acaaccgaat gacggttcgt tcggcggatt
    14881 aaagaccttc gcaatgaata caaaaggcgc cggcgttgta gtaggttatt tctgcgggca
    14941 ttggcacgaa caagtcgaag gggcgtttgg aacagtaaaa atgattcttt gcgacgtcgg
    15001 cttctctcat acagctagcc aagttgatac accggatgaa ttagcgtttt ataaaataga
    15061 agttgacaca gcaacaagaa aagtgacaag caaaggcgta gggcgcgcga gagacttcac
    15121 ttataactat taaggcggtg aacaattaaa tgttagattt tcaaagcaaa ccaaatattt
    15181 ttgaagaaat gagttatgaa gaggctgtga aatggttatt gcgtcaagcg gctatccatt
    15241 acgacggctc ggatcacgac gcgcacgtcc tagctactga aagcaacgcg ggctttgcta
    15301 caccggaaac agttatgcaa gcgcgtgggc gttggttacg cgattataag ctaccacaaa
    15361 aatatccgaa cattttagac attccgcccg gcaaatacgc aaccaaagcc ggatggggcg
    15421 cagacaaccc tgacgggatt gaagatgaca gttttgttga aatgatggta ttcgcggatc
    15481 acgattcgag aaaattaatc gtcgcttttg ctcgttatag cggcgaaatt tacatcaaaa
    15541 tgacacataa cagcgaaccg gtagagggtt ataactcgtt aggctggcgg cgcgtttaca
    15601 ctacttctgt tctttttgaa ggcgaattaa gaaaaggaca atcagtcaat ctgccagatg
    15661 atactttccg ttaccaaacg cttcgtatcc actacacaga cggtgacgga gactttgtag
    15721 aagaagtgaa acgtcaaaga tacgcgcgaa ttacaaaagc gaatttatgg aatggagacg
    15781 cgggagtgac gttcatcgaa tttgagctga caatcgaagc gcgaaagata acgatgtcaa
    15841 acggcagagc tttagatatt tcatccggca atgtttccaa tcccgcaatg agcaacaacg
    15901 tgaaaataac taagattgaa ggtgtgaaat aatggcgcat gtcatcaaaa aaggctctat
    15961 caaagtacct acacagccga aagactacga tttgcaagca acggggcttg tatttaaatc
    16021 atacgataat caaatagcgt tagagttcaa cgtcgaacaa cagaacggca caccggcgga
    16081 cttgctagga gctaacttgc gcttgttgat gtttatctat gatgaagtag atggaatgat
    16141 cacgaaagag ccaatccctt ttatcacgaa aaacctcatc actgaaagct tcttgaatgg
    16201 acaggtcgta tatatcttgc cagaagcgat gaaagcttat aacggtatgg tggaagctta
    16261 tgtttacatc gagtatccag acggatcaac aagtgataac ttaggcttca ccttccgtat
    16321 gaagcgttca gcaatcgacg gactagcgca agataaagca gactacttta ttgcagactt
    16381 tcaacaatta cttgatggag tcaaacaaga agcaacagat gctgttaacg cagcattaac
    16441 aaatgtggat tctacgattg aaaaggcaaa ccaacaaata aatgaatttg tagagggagc
    16501 cacacaagca attgatcaaa ctgttgacga ggtaacagag caactacaag ctactcaaac
    16561 taagattgat accgtttctc aaaacgttac atcggcacaa aacaatctta aagcagttga
    16621 agacaagatg aatcaaacca atcagcaaat cggcgacctc ggcaagctga aaaagatgta
    16681 cagtaacagc atcgacttcg ggaattatga ttatagtggg aatccgaatt taatgtccaa
    16741 actaaaatcg agcgatttta acgttggtta ccacgggtca ctaacttcgg ataacgaaaa
    16801 gctacatttt acttctgatg gtacaggaag cattattatg tttacgcgta ttaatacacc
    16861 tcagcttgct agtgggaaaa cctatactct gagtgcgaaa gttcgatttg atgaaggaac
    16921 tacaggagct attgataaat tacgtttggt gtatcgtaca tcaccaggag aaaagatatt
    16981 attggaagca aatagtacaa atattacaac agatgatgta gggaaagaaa taacaatcaa
    17041 aggtacagct aacgttaatt atcaaatcac aaatttagat cgattttata tgagtattag
    17101 ctttgttgac agggataaaa taaatggcgg atttaagttg tacgacatca aaatcgaaga
    17161 aggctcaaca gccaccccat atcagccaaa cttacttgat gacccttact ggctaggtaa
    17221 agcgcctttg ggtgagaata ttgctaataa gtctgttacg tttccaatca aatctagcgc
    17281 ctacagccta taccaagcta acatggaaga agaatttgtt ttaggtcaaa cctatacaat
    17341 taccatgaag gcaaccaaac cacctatcca aacgttcatt gtttacaacg aggatagtgg
    17401 agattataga tatggtaact tagagccagt agaagggtta gttgatacat ggggtctgac
    17461 ttttacaccg cagaaggttg gagttaacta ccccaaacgg ttaactatta tccagtatcc
    17521 ccaatcaaca acaggtgcat gtcaaattga ctggctcaag atcgaaaaag gcgacacacg
    17581 aaccccgaat attagtcagt ttaaatactt tggtgaaggc ttgaaagaca gtaacaatcc
    17641 caatgattac agttgggatg tcacacctga atatactgaa aaaggcttga atgatgctgt
    17701 taatgtgtat gatcctcaga gagttgaagg tttgaaaaac tttgccgatg gtattcaaat
    17761 agcaggagat aaagtgatca gtgaaaatga ttgcactgtt tatacattaa ctaaagacaa
    17821 cagtcaatcg tttatcgatg ggtatgcaac atttattaaa cacggaaaag aagttattgt
    17881 aaatggtaca gtaaagttca aaaaagctta tgcttttggt gtaccacttg atgatgaagt
    17941 cccagatgaa tttgtcgcaa aaattgttca tggcatgctt acaggtccgt caggaacaag
    18001 tagtgtatca aaagcgatgt acgtgcgaaa agacttagga acaattatta cgaatagcga
    18061 atttgctgca aatgaatggt ttacattcca tggtaattat tgggtagggg aggaataaaa
    18121 atgaaaaata tttggaaata cggacgaaca ggtggagagt atgctggaca agtgcttgat
    18181 gatatggtta tgactgttcc atttaccgat gttccaccac tcgaaggaat tcgtgctgat
    18241 ggggaaccac taacgattgc tgatcagatg tttgatccta aactgaacca atggattgtt
    18301 ttagtgaatg tactagatca caacgattta aacaatctca aagcgatgta tgagtcgtta
    18361 gaaaatgaga acggcgattt aaaacagctc aacgccaaac tcatgctaag cgatgtagcg
    18421 attaaacagg aaaatactgc attgaaagaa aaagcggatg gtttagcaca aatcaattca
    18481 aaaacgatgc ttgcttcgtt ccaaaatagc aaagacattg cagaaattaa agagcaacta
    18541 aatccagctt caaagggagg tgagtagtat gtttagtttt agcgatgtga aaatgatgta
    18601 tgattggggc tgttttactg acgatcaagt tcgactattc gttccactat gcattacaga
    18661 cgaagaagca gaaaaaatca ttaataaaga taagagcgca tcttaagtga tgcgttttta
    18721 tttaaggtaa aggagttgtc acatgattaa tttaggagaa tggggaacaa tcgcaggatc
    18781 aatcactgcg attgtttctt tgattttatt agtaataaga ccagtcactg catctttctc
    18841 gaagattact gaaactcttt caaaagtaag tcacaattta gatttgctga ctaaagattt
    18901 agaatcgagc aaatcagatc gattgatgat tcatgaagaa ctaaagaaac acgatgaaag
    18961 attagataca catacagaaa aattggtaga acacacacaa caaatcaaaa ctttatttag
    19021 agaaagatct cggtaaaaaa gaaaggagtt aagaagaaat gattttaccc gataagtatt
    19081 atcaagtcat taaatggaca gttttaacag tattgccagc tgcatctgta ttagttgcaa
    19141 cactaggcaa agcgtatgga tggaatggaa cagatatgac agtactcact atcaatgcag
    19201 tagcaacatt tttaggcgtt atcactggcg tgtcggctta taatttgaaa aaataggagg
    19261 aaacaaatga aaaagaaaat tactattact gcgatgagcc tattaacggc tcttttttta
    19321 ttgccaatta atgggtttgc ctatacgatt aacaatgaat ttaatttagg cccaaacgaa
    19381 ggtagctcac aagtagcaaa taatcagtac attttactgc atgaaacggc taatgaaaca
    19441 gcaacaggac gcaatgaagc gcagtatatg caacgttcat ggactagcgc ttatactgct
    19501 tatattgtgg gagacggcgg aattgtttat caagtcggtc aacctggtta tgtacagtac
    19561 ggtgctggtt cgtatgctaa tgcaaatagt cctgtgcaga ttgagttaca acacacacat
    19621 gataaagcaa cgtttgagaa aaactacaag gcatacgttg aattagctag agattcagca
    19681 atgaaatatg gtattccact tacactagac acaccgtata atcaaccagg gatcaaatcg
    19741 catttatggg taacacaaaa tatttggggc gatcatacag atccttacgg ttatctttct
    19801 gaaatgggcg taagtaaaga aaaattagcc tatgatttgg ctcatggatt taccgatgaa
    19861 aatccgacaa cttcagatga taaaccagtc attgatccaa ctcgagcagg tgctgcaaat
    19921 cctaccctga cagatggaac aaattacgcc cacattgatc agttcggaga aatcgaaaac
    19981 gcaaacttac atgtggctgg ttggcacatc gctaactata aatacgagta tatcttcatt
    20041 atggattaca atactgggaa agaattagct cgagtaaaag ctgatggaat atatagacca
    20101 gatgtaaatc aagcttataa tactttagga aatgttggct atcatgtatc ttttaacatg
    20161 cgcaacttcc ctaataagaa agtctatgta atgatgcggg caacgaatga tccagaaggg
    20221 aacactaaag gcggagcaca agattttcat gataaacgct ggtatttaaa tattccgcaa
    20281 cgataaaaat agcccctcgt ttttgagggg aagtacataa tgcaaatttg tccataactt
    20341 attgattatc ttgtaaaaat gcggtaattt aatagttagt gagaagaggt gcttaattat
    20401 agttaaaaaa gaggaaatag aagcagcatg taaccaagca aatgttaggt ttattggaga
    20461 agctttatct ggatatccta agtataaata cttacacaac tggttacaaa gtaaaagttt
    20521 ttatcttaat aaagaaagat gcatgcctaa taaaaattat agggtttata aaagaggaac
    20581 tattgtatat gttgattttg gggtgaacgt gggttatgag ttatctggta atcattttgc
    20641 tattgtttta aataataaag ataattcgaa aaatggtgtt gtatgtgtag taccaatctc
    20701 ttcaaaaaag aaaagtaatt atgtatctgt aggaaaaata ttagaagttg ctagtattaa
    20761 acaatttata agccaagctg ataaattaaa agagaaactt aggataatta ttttactttc
    20821 attaaataga ggcatcattg atgaaagcga tttgaatagt tttattaaag atattgaagc
    20881 taaaggtgaa aagctttcag tggaagaagt agaaaaacga gctgtaaaac ataatttggt
    20941 ttgcgagaca agggaacaag taattaaaga aataaaatca ttatctgaag atatggtaaa
    21001 atatcagaag gtgtttaatt gctacaagaa atatacacaa gaatcctatg taatgccact
    21061 taatatccaa acgattagta aaaatagaat tagaagaatt aacaagtttg atccttctgg
    21121 aaatatgaag gcacctggaa atgtcctcaa tgaagtagat gaaagtttaa aaaaatattt
    21181 tacaaagtaa acgatatttt tgttgacatt tttctgttcg ttagttacca tgtagttata
    21241 gaaggacgta agcgcctatt tttaatgtac acatcgggac gtatgcgccc acatagaaac
    21301 atagttgaga gacatctata tggtgtctct ttttttatta atatgcaaaa aagtctagtt
    21361 ttttcaataa tatttatgta ataataaatt agccaccaca acaaagaatg aaacccatta
    21421 ttatctagtc tatgtccatt ctttttgttt gcagtagttg tgatggcttt ccgtactctt
    21481 agctcagttg gttagagcag acggctcata accgtccggt cgtaggctcg agtcctacag
    21541 ggtacatact ctaagtgatt taaattgcga ataaaatata aaaatgactc cccttttgac
    21601 ccccccaagc agtatatgga tgtctctaaa agttgttttt ttagataata aaaagctgat
    21661 aataagcgaa aaacacttaa aatcagcttt aaaccctatt ctcgaaatcc ggcgaaccgg
    21721 ctaataccgg cgcgcaggtt caaatcctgt accttcctta tatcaacgat tagaggttgt
    21781 gaagaagctg tcctgcatca agtaataaga acggccaaac aaaaatagct tttcctattt
    21841 tttcgtttga ttgggcttat taccgcagat gcaagctttt gaacaccgtt tgttcggaat
    21901 aaggggctgt gacaagactt ttgtcacagc cccttattgt tgtactttta acctacaata
    21961 ttttttgatt ccccctgagt actatttttt ataaatgcta gtaaatcaat cttctttggc
    22021 ctttttttga taaaaaaaat actagatgta agataaaagt gtaaaaacga tttgttttag
    22081 gaggggaaac gatgtgtacc gcaatcactt atgcaacgaa agaccattat tttggaagga
    22141 attttgatta tgagatgtct tataatgaag tggtcactat tactccaaga aattatcgtt
    22201 tcgattttag aaaggtaaaa aatttagata aacattatgc aatgatagga atagcagctg
    22261 gggtatccaa ctatccactc tattatgagg ctacaaatga aaaagggttg agtatggcag
    22321 gactgaattt tcctggcaat gctgattata aagaattaca agaaggaaaa gataacgttg
    22381 caccatttga gtttattcca tggatactag ggcaatgctc aaccatagac gaagctaaag
    22441 aattattggc tactatcaat ctagtcaata tcgattttag tgaaaaacta cccttgtcac
    22501 ctttacactg gttattagct gataaagaaa aatcgatagt aattgaaagt atgaaagatg
    22561 gacttcattt atatgataat cctgtcggtg tgttgacaaa taatccgcca tttgattatc
    22621 aattatttaa tctgaacaat tatcgctcgc tatcaaatgg a
//
LOCUS       DACCVH010000042        22266 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.042, whole genome shotgun sequence.
ACCESSION   DACCVH010000042 DACCVH010000000
VERSION     DACCVH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.042"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(112..630)
                     /locus_tag="IVV98_001654"
     CDS             complement(112..630)
                     /locus_tag="IVV98_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP7807313.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(632..1249)
                     /locus_tag="IVV98_001655"
     CDS             complement(632..1249)
                     /locus_tag="IVV98_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP7807314.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1246..2100)
                     /locus_tag="IVV98_001656"
     CDS             complement(1246..2100)
                     /locus_tag="IVV98_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807315.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2097..3008)
                     /locus_tag="IVV98_001657"
     CDS             complement(2097..3008)
                     /locus_tag="IVV98_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807316.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3049..4383)
                     /locus_tag="IVV98_001658"
     CDS             complement(3049..4383)
                     /locus_tag="IVV98_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7807317.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4591..5421
                     /locus_tag="IVV98_001659"
     CDS             4591..5421
                     /locus_tag="IVV98_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP7807318.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5665..5914)
                     /locus_tag="IVV98_001660"
                     /pseudo
     CDS             complement(5665..5914)
                     /locus_tag="IVV98_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6105..6299)
                     /locus_tag="IVV98_001661"
     CDS             complement(6105..6299)
                     /locus_tag="IVV98_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807319.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6804..6989)
                     /locus_tag="IVV98_001662"
     CDS             complement(6804..6989)
                     /locus_tag="IVV98_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807320.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7839..8180)
                     /locus_tag="IVV98_001663"
     CDS             complement(7839..8180)
                     /locus_tag="IVV98_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7807321.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8180..8410)
                     /locus_tag="IVV98_001664"
     CDS             complement(8180..8410)
                     /locus_tag="IVV98_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7807322.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8697..9035
                     /locus_tag="IVV98_001665"
     CDS             8697..9035
                     /locus_tag="IVV98_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807323.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9240..9479)
                     /locus_tag="IVV98_001666"
     CDS             complement(9240..9479)
                     /locus_tag="IVV98_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP7807324.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9455..9802)
                     /locus_tag="IVV98_001667"
     CDS             complement(9455..9802)
                     /locus_tag="IVV98_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP7807325.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10534..11115)
                     /locus_tag="IVV98_001668"
     CDS             complement(10534..11115)
                     /locus_tag="IVV98_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7807326.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11298..11924)
                     /locus_tag="IVV98_001669"
     CDS             complement(11298..11924)
                     /locus_tag="IVV98_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7807327.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11946..13277)
                     /locus_tag="IVV98_001670"
     CDS             complement(11946..13277)
                     /locus_tag="IVV98_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP7807328.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13432..13833)
                     /locus_tag="IVV98_001671"
     CDS             complement(13432..13833)
                     /locus_tag="IVV98_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP7807329.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13919..14125)
                     /locus_tag="IVV98_001672"
     CDS             complement(13919..14125)
                     /locus_tag="IVV98_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807330.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14220..15722)
                     /locus_tag="IVV98_001673"
     CDS             complement(14220..15722)
                     /locus_tag="IVV98_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP7807331.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15740..16195)
                     /gene="argR"
                     /locus_tag="IVV98_001674"
     CDS             complement(15740..16195)
                     /gene="argR"
                     /locus_tag="IVV98_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP7807332.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16293..16910)
                     /locus_tag="IVV98_001675"
     CDS             complement(16293..16910)
                     /locus_tag="IVV98_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807333.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17131..18504
                     /locus_tag="IVV98_001676"
     CDS             17131..18504
                     /locus_tag="IVV98_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7807334.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18579..19691
                     /locus_tag="IVV98_001677"
     CDS             18579..19691
                     /locus_tag="IVV98_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP7807335.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19763..21400)
                     /locus_tag="IVV98_001678"
     CDS             complement(19763..21400)
                     /locus_tag="IVV98_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP7807336.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21568..22176)
                     /locus_tag="IVV98_001679"
     CDS             complement(21568..22176)
                     /locus_tag="IVV98_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7807337.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         6499 a         4537 c         3878 g         7352 t
ORIGIN      
        1 acaaaactta agttattaag acaaatgaat aaacaactac gctttcctcg aaacaaaaaa
       61 ataaagcaca aatgcgcatt tacgcactca tgctttattc gtacaattaa ttcagataac
      121 ggcagcgcat aggatgccaa taacacttcc taaaatagct cctcctaaaa tgtcagtagg
      181 ataatgtaaa agtaaaaaaa tcctcgaata agcgatcaaa caagcaaata aaaaggctaa
      241 tattcctgca actggactta attcgaacaa cgcagctact gataaaaagg ctagcgctgt
      301 atgtcctgaa ggaaaagaag aagtcttcgg tttacttgtg taaaggacaa gccgacgatt
      361 tttttcataa ggtcttttcc gtcttgtcgt ttttttgata aaaagcaaac caacaaaaaa
      421 atagatcaaa ctgccgataa gaatggctag accatattct ctagtatcag gtatcaagac
      481 taaaacagca gcaaggagca accaaataaa accaccatta gagatattac tgataaattt
      541 caaaaaattg atttttcgac tatccgtttt ccgttgcttg gcgaacttgt tgataatact
      601 atcatcgatt ttagcaatca aacgcaacat gttattcctc ctttttaaga accttttctt
      661 gcgtacgatg gataaaaagc aggacttgaa aataaaacaa gaaactgaaa cctaataaag
      721 caaaatagat tggtcctgca aaccagaatg cgacaagaag gatcaacgtg cctgccaaat
      781 agaaaagcgc gcttttgaaa tcattaaaaa acaagaaaaa tgcagtaatc caagaagctt
      841 ctttttgttc cagttgaagc aagattttgt aactaaagag aagcgcgctt aatagaagca
      901 aaaacaacgt agtatacatc aatgtatagc caattccccc accccaatag cggaaaatct
      961 gataatcgat caatagaaga agaaaataaa cacttgctaa actatcttgc tttccataaa
     1021 gagagaagtt ctcacgaaac tttttccaga atagtgaacc gagctttttc tcttcatttt
     1081 ttttgtaatg ataaatcata tacagaactg ttcgacttgc agttcctaat gtgaaaacag
     1141 gcaagacgca caggaaccat agtagctgta aatggataag acgtggaatc cattcaatga
     1201 tttctaagaa ataatcattg gcttttttac caatcgatcg attcatcatc cttttgaacc
     1261 tcctgtcaaa tccatccctt caatgaaata acgttgtgca aaaaagaaca gcaaaatcgt
     1321 cgggatcaag acaagtgttg ctcctgccat cagataattc cattgtgtcg ttgcttggtt
     1381 ctgaaaaact tgcaagccaa tctgtaacgt gtatttttct tgatcttgga tatataacag
     1441 aggacctaag aaatcattcc aagctgcgtt gaaggaattg atcgcaatgg taatcaaggc
     1501 aggtttcgtc aatggaagca tcaaatgact ccaaatatac aaatgattcg ctccgtcgat
     1561 ttcagcagct tcgatcaatt cattattgat cgataagtaa aattgacgca tcagaaatat
     1621 attgaacgca ttgccgaaga acgatggaac gatcaggggc aaataagtac ctacccagcc
     1681 gatcttggag aataatacat attgagggat catcgttaca aaccccggga tcatcatcgt
     1741 agaaagaacc aaagcaaaca tcagcttttt cccaggaaaa tcaagcttcg caaatccata
     1801 agcaataaaa gaatttgaaa ggacattacc gatcactact agcacagtga tgaataatgt
     1861 atttcttgca tagcgccaaa aaggaaaggc ggcaatcgta tccagatagt tttcccatac
     1921 gattttttct gggaaaaagg tcggaggata acgaacgatt tcttccattg gtttcaatga
     1981 agtaaacacc atccaaagca atggaatgat caaaatgatt cctattactg tcatgaggac
     2041 ataacttagt attttttttg tttgccgatt cacactggtc tttttgaaat aatccatcat
     2101 ttgccgtcac ctccagaata atagacccac ttaggtgcaa gcttcaaatt gacaaacgtc
     2161 agaaccaaca cgatcagaaa caggatcatt gacatagcca tcgcataacc catatcaaaa
     2221 gctacgaacg ccttgttcca catatgcaga ttataaaaaa gcaaagaatt tgcaggtccg
     2281 cctgttccat ttttcgtcat gacataagct tcttgaaaaa tttggaaaga accgatcgta
     2341 gaggtgatca catcgtaaaa aataatagga gtgattaatg gcaaagtaat acttttgaac
     2401 tttccccaaa cgcctgctcc atcgatttct gctgattcat ataaagatct aggaacattt
     2461 tgtaatgtag ctaagtaaag tagcattgct cctccagaac tccatatttt catcaaaatc
     2521 aacgcaggtt tcgtccattg tggatcaaac agccaagctg gtccagggat atggaaccag
     2581 cccagaaatg tgttgatcaa tcctgcagat ggagaaagca gctgcatcca taagatgtag
     2641 actgctactc ctgataagac tgccggtaaa tagaaagctg tacggaatac actgattcct
     2701 ttgatttttt gattgagtac tgtggctaaa aacacactga aaatcgtcgt cagcggtaca
     2761 ttgaagatga cgaaataaac ggtgttgtat aacgatttcc aaaataaatc atcgtgaacg
     2821 aacattcttt tgaaatttgc tagaccaatg aaattcatct tggatgtcaa attataatcg
     2881 gtgaaactac caataactga aaaaagcata ggccctagca taaataccaa gaacccgata
     2941 ataaaaggcg agataaataa ataggcccat cttgcttctt ttttctttcg gatagataaa
     3001 cgcttcaaat tttcttgcct cctctgtacc tagacagtca aaaatggatt attgattttg
     3061 cttgactaag ttttctactg ctttttgtgc atctgccaat ccttcttttg gtgattttgt
     3121 tcctaaaaga atctggtcaa tctgttcatt cactaatgtc gtgtaatccg gagcatctaa
     3181 aggaactggt gtgatcaccg tatttttaaa gttttcgtcc gccatttgat agatcatttt
     3241 tcctttatcc gttaggttgt cattattcac taaattctca ttggctgtct tgctcgccat
     3301 gatatcaaaa cttttttcgc cgaatttttc ttgtacttct ggagaagaaa gatatttgat
     3361 gaattcataa gaggcctcag gatcttttgc tccgtatggt acttccaaga cgaatccgcc
     3421 accccacgac caatggcctg aaccttcttc tttttctggg agctgcatca cgccaaaatc
     3481 aaaatcatcc ggtgcatttt ccatcaaact agagtaataa ttgatatttt gggcacgcat
     3541 ggctactaat ccggaaataa atggatcaga tacaccagac ccaaattcgg cttctaattt
     3601 attgatcgta tttttcccat aataatcttg ccagtcttgg atccactcca aggcttccac
     3661 tttattttta gtatcaatct tgactttttc atctttgtca aaccaactag tcccgttatc
     3721 tgcgtttagc gcccatacat cagcccctaa attccataat ggataaaaac cgatgcgtgt
     3781 aaattctttt ccttcttttt tatctagttt acgtgctgtt tcttctaatt catcccaagt
     3841 tgtcggtaga tcttgttcac tgattccagc ttctttaaat aactttttat tataaaaaat
     3901 gacttgtgta tctgtattga atgggatcgc ataaggatca ccttcatatt ctactgtatc
     3961 ccaaagctgc ggataaaaat ccttagaagt gtctttttct acatatttgg agagattagt
     4021 tgcttgctgt gcttctgctc tttgggcaac ggaatttatg tcctgtacaa taacatcggg
     4081 tgcatttcca gctgttattg cagataaaga tttagtccag atgtcacccc atggctgata
     4141 cttataattt acatggatct cgttttgtga ttgattgaaa tcctcaatga tttcttcgat
     4201 agcttctttt cgtgcaccgg atccccaaaa ggaccagaaa tcaatatttt ttcttccatc
     4261 acttgttttt tcagaagaat ttgctgcact tgaactggca tcgcttgcat tacttgatcc
     4321 gcatcctcct aataaaaaca atgctgaact tgccagcaac cctgtaaaca ataatttttt
     4381 catattttac ctccaaattt taatgtaacc gatgccggtt ttaatataac gatatcattt
     4441 tgttctgaaa ataacaattt ataaggtatg attctaaaaa aattattaat gataccaata
     4501 ctttatataa ttcgcgagcg ctttctttga attttttaat ctttcgtagc agaatgagaa
     4561 tgtattaaaa atagattagg aggaattttg atgtttagac accagaaaga attgcagttt
     4621 gaagcaaaac cagatcgtcc gaatccatta atcgcgaaat atctgcagga gctgatcggc
     4681 ggccaatatg gcgagatgag tgtagctatg cagtacctgt tccaaggctg gagctgccga
     4741 ggagaagaaa aatataaaga tatgctgatg gacattgcaa cagaagaaat cggccacgtg
     4801 gaaatgttgg cgacaatggt tgctcgttta ttagagggtg cgcctgttga agatcaagaa
     4861 gcagcgatgc aaaaagatcc aacaatcggt gccattatct ctggaatgaa tccacagcac
     4921 gcgatcgtag ctggcttagg acctcgtcct gctgacagcg tgggcaatcc atggagcggt
     4981 gcctatatca ttgcgagtgg caacttgtta gcagacttta gagctaattt aaatgccgaa
     5041 tcacaaggaa gacttcaagt agcacgtatt tacgaaatga tcgatgatcg tggcgtaaaa
     5101 gatatgctgt ctgttctcct tgcaagagat agctatcatc aaaatctatg ggaatgtgca
     5161 gtgaaagaat tagaagaaaa agaaggttca atcttagtcc caagtacttt cccgcgtgac
     5221 aaagaacgaa aagacattgc ttatgacttc tataacttct cagagggaga ccaaagtagt
     5281 gaaggttctt gggctagtgg caaagcactg gatggcgaag gcgaatatca atggttgaaa
     5341 gaacctaaga tcgaaggcgc tgcaccaaaa ttagaaccag taacaccaaa aatgtatggg
     5401 acacctccat tcaagaaata aatatctacc cgtagaaaca cccgtttttt gttccacacg
     5461 ctttgtgagc aaaactgact aaagtcatta atcataacca cccttcaaaa gggtggtttt
     5521 ctctagagct ataagctcaa atcaccggcc agcgcctaaa gacgctggct ttcatatttt
     5581 atgttcaagc catattgcct ttgccagttt tgcccacctc ttaaaaggtt tatgtactac
     5641 tccttagccc ttaaaaggat cgtcttactc tcgtacactc agcttatcta acgcactatc
     5701 atgtttttct tgttcttgaa tgtacttttt gatggtcgct tcattttgtc ctacttttgt
     5761 cacatagtat ccttccaccc aaaagtgtcg atacccaaat ttatatttta gatttgcaca
     5821 atctcttgat gatctcctga atattggctc gatattgatt ataaattatt tttcttctat
     5881 actttggtgt gaatacaatg tggtatttac acatctactt tgtacgggct aaactatttc
     5941 cctttattgc tccacccgca tagcaagtgg ttttgtattt caatcgctcg gcgcgctcaa
     6001 ttaggtctaa agacaataaa tctaaaaacc cgctgcttca ctgacagaaa caacgggttt
     6061 tcagaaaaaa atgaaatgaa aaagatctct tacggcaatc tattttattt ttttgatttt
     6121 ttataaatgg aaaatgcttc aagaagtcca agaaataaag ccgtataaaa acaagaacct
     6181 atgaaatctt tatttattag atattcaaca gaaatcccga taacactagc caacaatata
     6241 tttatcagaa gtgtaaaata aggatgcttt ttatagaata gaactagtgt tgttttcata
     6301 gactctcctt tcttcatatt tccaattaat cacaaattca cggcattact agaaaaatta
     6361 aaggggcgca gaagtggaaa aatactcttc gactttccct acaaaccagg ccatcttgtg
     6421 tttaataact ataccaaatc taaggtacct ctaaatctaa attccatttg tggcggtgac
     6481 ctccaatttt taactcttct atctcccatc cagtatacat aaccttgata cttcgaccac
     6541 ttatatatcg aacacacaaa tacctatcca ttgcaggagt actacctaac ttagttgcta
     6601 cttgcatcta aataacagct gaaaagatag gacttactct tagtaaagta tctgaactat
     6661 taatttttaa actatcattt ttatcctcaa ctacatgcac atctgttgca acttcacttt
     6721 ctgtctcatc cagataaatg attaaggaat cgggaattgc aatatcttca gctgacgctg
     6781 gaatagttga gctaaattag tcatcatatc tttattataa aataaccaac agcaaaaaat
     6841 acaatgaaaa acaaacttgg aactaatgta tcattaataa atgttgaaaa attcagcaac
     6901 tcattactgt atgattttag cagcccaacc aacatatacc ctataaaagc taataagatg
     6961 gttaggaatc ctttagaatt tttactcatt catagacact tccttaaata acttttatta
     7021 tagaaggtat tgtaaataat aatattgaca aaaagtgact caaaataaaa aaaaccttac
     7081 attatactgg aatgaactgt attgatagtg tacctaaaag ctctactgac ataagatcgt
     7141 gtaatcggta aagtaatttt attaattata cgggatgtaa tcaattagag aataaactaa
     7201 tcataaaagg tacttttaca ttcataattg tcgctttgag attctacttt ggttcactat
     7261 ctgacccaat tgcacatttt cgatcattac aagtattggt gtcgttagaa caactaaata
     7321 aaaactagcg gtagattttt cagaatctat gctaatttct gtatggatgt tccagtgatg
     7381 gcaaatttct cttttcattg tttttcttgt cgcatgatat gcctttttgt gttattcagt
     7441 taaactatag aaattctttc ctagacagat cttgatccca aattttacgt ttttgagcat
     7501 cgatatagtt taaaatgaca ttactcatat ctaaagagtt tagatttttt aggactaaaa
     7561 ctgtcagttg ttctttttct tctttctgtt aaagtattgt cgcgactttt cgtatacgtt
     7621 aagatatgtc gtgaaaaaac aagttttgtg acacaaaaaa acgaatgact tgaggaaatc
     7681 acctcaatca ttcgtttaaa atgctatata ttctttagtt taagatacgg aaattaatgc
     7741 catcgaccac actagtagaa tgaacgacat ttacttggcc tttttttaat ttcgttatgt
     7801 ttagcatata aaaatattat agagtttact tacaatgctt aaaacatata ctgtataatc
     7861 tgatcaattt tagccatgtc ttgcaatggt aagttttcta tttttttgag ttttcgttcc
     7921 ttaaaatcaa gagattttaa ttgtgtaata attacttgtc cttttatatc tagctcttca
     7981 ggtaatgagt aacgtgtcgg taaattcttt atagtggaag taattggaca tatgaccgaa
     8041 aacattgttt tacggttaaa ttcataacga gagacgacta gtcctggtcg tcttttttga
     8101 atttcttttc ctacggaggg atcaaaatca atccatacaa tatcaccttt tttaggaata
     8161 taaattcttt cttctgacac tataaaattt ctctcccttc aggagttaaa tcttcccatt
     8221 cgtctttctc ataatactcg gcctcttccc caccactaaa tggatcttca atttttggaa
     8281 ctaacgtaat tgttccatca tcagaataca caacgatata ttcttggttt tctgaaggtt
     8341 tctttccgtt atcagaaggt aaagttacca ctacagaact tccttgtaat ctagattttg
     8401 taacaagcat tatcatcact cccttaataa aagtatacta tataacacta agtaacgcaa
     8461 aattcccctt tgtaaactat ctagaaaatt gttttgttta aagtatatct tattggatat
     8521 aaatagaaat aaattgtagc cagttcattt tttctttaac taaaaaaata atccaagaaa
     8581 cattgaacct atggatccaa aagctaccca aatactatag ctaacccccc gctaccttca
     8641 attttgcaga taaaacgctt tgggagaaaa tttcaaagac aacaggccat cctatcatgc
     8701 ccgattataa acaaaaagct ggctattcct tttgctctga caaatttcaa ttgggaaagt
     8761 tcacgaaact agcaggtgaa gaagtttcaa ctgttcggat caaagaatgc ccgcttcaaa
     8821 tagaaacatt ggttcaacga atttcaacta gacaagactt tgctattgta gaacgtgaga
     8881 tcgtagctat ttttgtagaa gaagggattt tacatgatcc aactcatatc aatgtggata
     8941 aatggcaacc tcttatctat aaattcagag aatatacaac tgccaaccag tcgttaactt
     9001 tgaattttag attccaagaa ttcaaagagt cataatgata aacatcgtta ggtataaata
     9061 aaaaagactc gcagcacgag taaaaaacaa atagaagcta tacattagaa aggtcgactg
     9121 tgaccctata gatgcagtat atgcagctta tgagcatttc ttctgttctc tttgtttttg
     9181 ggatctgtgc tgaagtcttt ttcgtttttt gccgctcttt ctttgaaaaa tcgattatgt
     9241 tataccttct ccattactaa ttcaggcatc tgctgagtaa tgatttttcg cgcaaaagaa
     9301 atatctgtta cccaaggttc gatttgttct tcagtcaaga caagcggcat tcggtcatgg
     9361 attggtgcga ctgtgcggtt aggttcagta gtcattatga ttgattctgc cattttttca
     9421 tcctgatggc tacgataaaa accgccaata tacactattt tttccttatt tgaaaacata
     9481 aatttgtctt tttcttcatt ccactcattg ggaaaacaca acgattttgc aaaaatggtt
     9541 gatgaaaggt ctttttttct tctactgtct ctgcacgggc attaatcatc aattgtcctt
     9601 ttttaaatcc ggtaaatccc cacttcatga tttccggagt gaggatgttt tcttcctctt
     9661 ttcttaacgt cacaacaaga tttgacggaa aaacttctcc agctgctaat tctgctgcct
     9721 gcttcggttg tttcgtctgg gcttctcgat aataattctg aaggagctct gactctagat
     9781 caaaaaaata acgaccacac atcctaatcc ctcccaatct ttttttctat catacactgc
     9841 aacaagaagt tcgcaccaac aaaacgcttt caatttttgt agaactaaaa aagttgtgac
     9901 aagtgacaaa ctctccagtg aatggtattc tcctgccaac tcctcggtca caagtcacaa
     9961 tattcaacaa acatgagaag ctgctttttg aaattgttcc ttgtgactcg gagtgaaacg
    10021 gcaggcttac gacctctggg taaacggtgt tcaaaagcca gtttctcggt attaagccaa
    10081 atttatgcaa aaatgtagaa agctattttc acaaaatttt tcttaatact cgaaactaag
    10141 cgactttttc acaacctctt ccttaaacgg tgttcaaaag cttgcatctg cggtaataag
    10201 cccaaccaaa cgaaaaatat gagcagctat ttttatttgg ctgttcttat tacttgatgc
    10261 agggcagctt tttcacaacc tctccactaa acggtgttca atcagctaac cttcggtatt
    10321 agctcaaaaa acggcaaaat atgaggaact attttgccgt ttgtttctct aatactcagg
    10381 tcaaagcgct gatttcacaa cctctaatac acggtgttcc agaagtagct tcttcgaaaa
    10441 ataagccgaa atttcacaaa aatttgagaa gcaattttcg taaattcctt cttatttctt
    10501 gaagctgacc acttctgtca caacctctaa ttattaaaga accttttgcg aagttaacaa
    10561 tctttctttg atcaattgaa aattctgcct aagtagtgat agatcctgtg tgactttcaa
    10621 caataagata cttccctgga tttcagcaat caacgctttg gcttgacggt ctgcttcttc
    10681 atcggacagt ttttcttcag aaagtgccag gatattttgt ttcgtatact tgacccattg
    10741 attgactaat tctagtagca acagacggta ttcttcatcc actgtactca actcaataat
    10801 caaattacct acaggacagc catgataagt gatctgtgtc tcatgatcag cgaaaatcca
    10861 gtccaacatt tcttctaatg cttcttctgg ctgttttcca gcatttaaga tgtcttcgaa
    10921 caattctgtc tgccatacgt ccatatgcgc atggatcacc gctagacaaa cttctttttt
    10981 tgaagaaaag taataataaa attgaccttt tcctgtatca gaagctgcta gaatatctcg
    11041 gattgacgtt tcatgatagc cttttttata aataagatct ttggtcgctt ccaagatctt
    11101 ttcctttgtt ttcaatgata ttctcctttt tcatttctca tagtcctata ttatacagta
    11161 aattcatcat tttttcttct taatcgttta aaaaagactg tgccaaatta tctgacacag
    11221 ccctcactat aaaactgttc tcatatagct agatgttcat tgattcaaga actgcgagga
    11281 caaaagcaat tcctatctta tgatagttgc tctaatactt cctctgttgt catcacttga
    11341 tctgcaataa agccaaagtt cgtcaacgct gcatccattg cttcttggcc aggagcacca
    11401 attgcatctg tcgctaccac aacattgaat ccactctcta ccaattcacg catatgggaa
    11461 tcgctacaca agtttccgtt cattccacca agaattactg tgtcgattcc attttttctc
    11521 aattggagcg ccaaatcatt gctttctggt ccaaagattt tatgaggaga gctgatgatc
    11581 gtattttcat ccaaataagg tttcaattct tcgataaaat cggctcctga accttcttcc
    11641 actgattcat attgactttt tctagcaaac atctgctgct caagcatcat atgttctcct
    11701 gcaccgccaa attgccattt atggtcatgt gggtaaaaat aatgaggaga aataaagagt
    11761 ttgtatcctt tttcttttgc ttgttttacc atttcaatca tattttcgat cgtattgtat
    11821 ttttctaaga tatcttttgt caaaccaaag ccaccgcctg ctggtttcaa gaactcgact
    11881 tgcgggtcag tgagaactac tgctgtattt ttattattga acatggtgga ttctccattc
    11941 gttatttatt ttaatacatc atttagagct tcactcattg tcggatgaga atagatttga
    12001 tctctcaata acgtataagg aagttttcca ttcatagcta gcgaaatcaa gttgatgact
    12061 tcatgagaat cttccgcata gatacttgcc cctagaatca agtcagtttc agggtcgact
    12121 aaaactttga atacaccttt aggatcttct aatacttgtg ctttagggac accgcttgtc
    12181 atatacttga ataatttgta attgacgcct tgtgctttgg cttgtttttc tgttaaacct
    12241 acattggata aagtcggagt gataaataca ctgtaaggca cagctttccg gttattcgtt
    12301 gttcgtttat tctcgccctt caactgatcc ataatgattc gataatcatc tagagagata
    12361 taagtgaact gcaatccgcc tttgacgtct ccaatcgccc aaatgttgtc tgcatctgta
    12421 cgaaggtatt catccacagc gattgctccg cgatctgtta gtttaacatc tgtattttct
    12481 aatccaagtg atgctgtact tggttttctt ccagttgcag ccaaaacttt tgacgcttgg
    12541 attgttactt cttggccatc ttctgtaaag gtgacggcag ctgttgattc ttggtctgct
    12601 acttgatcta cagatacacc tagatggaat tcgattcccg catttgtcat gtcttctaaa
    12661 atcatttgcg cgatatcttc atcttcacgt ggaagaaatt cagaatgggc atcaagaacg
    12721 acaactttag atccgtattc attgaacatt gatgcaaatt ccaagccaat atatccagcc
    12781 ccgatgatca ctaatttttc cggtaattgt tcctgatcca tcgcttgcgt agaatcaatc
    12841 aagtagcgac ttgtattcaa tcctttgatt ggtaaaatga ttggttcaga accagtattg
    12901 atgaaaatcc gttcgccttc aacaatcact ttttcaccat tattcgtcac ttcgatttga
    12961 tggttagaaa gaaaacgtgc tgtaccgtcc atcactgtcc cagttgcctc atcgctgatc
    13021 atatgataat ttttggcgcg aagcatgccc gtcaattttt ctttccgagc aacagcctct
    13081 gtaaagtcga ttcctctttc tccattgaaa atcaatgatt tagaaggaat acagccgatg
    13141 ttgatacatg ttccgccata catacgtgtt gacttttcaa cgactaaaac cgattcacct
    13201 tttgaagcta acgccttcgc taaagtctta ccgccctttc caaaaccgat cacaatattt
    13261 tgatattttt ccatcatttt tccctcgctt cttttttacc taccgattgg tacaaaaata
    13321 tgataaccga taattgtcta ttctccaaat catctgcttt atttgtcaaa aaaaaccaga
    13381 caaaaagcgg tcctttcacg tttttagtct ggttcgattt cctttattct tctaaacaat
    13441 cgttacttct acatcgatat ttcctctagt tgctttggag taagggcaga attcatgcgc
    13501 atcttctgca attttttggg cttcttcttc gctgatgcca tcgatatgca cttctaatac
    13561 tacaccgatc tgatagccgc catcatctaa attataaaga gagacacgtg cttttactgt
    13621 ggactctgct gtcattcctg cttctttgat catatgttgt accgccccat tgaaacaaga
    13681 agcataacct gctgcaaata attgttctgg atttgttcct tctgcatgga ttcctggagg
    13741 agtgattttc atatgcatcg agccatttgg tgcctcgact tctccattgc gcccgccatg
    13801 gttgatcatt gctgtttcgt atgctttttt cattgtactg ctcctttcga ttgaccattt
    13861 gctacttggc tataattata gtgtatgaca agtaaggcgc tttctacaaa aattctgctt
    13921 attcgaatac cagaatgccg tcttctacta tttttccaaa aaacaaaaaa atactactcg
    13981 tgaacaacag cgtcatattt gttccaaaat aaatagcaat cttttctaca taatctttta
    14041 tatgattgat tttaagatac atatatacca gaaagttgac cccataaacc aatactgtta
    14101 aaaaaataac catattcgtt accatttttt cctccttttg ctggtctccc taccagcact
    14161 cgatttaacc ataccacttt ttttgccgtc caagcaacta gcctttcaaa aagactggtt
    14221 tattctgctg ttaatgattc aagatcagaa aaatgtccga ataattttgc taattttact
    14281 aacgccaact tgttctttcc gaattcatca ttttctatct gtaatactag taacggctca
    14341 tgtaagctta aacggatcaa aaaccagccg tttccgtatg gctcttctag atcatatcga
    14401 ataccttctt cattttccgg gtcgaagttc atcccttttt cttcttccaa cagtcgcttc
    14461 atttcttcta atatcttgtt tccttgttcg cgtggttcat cgctgaacaa ttttaatcgg
    14521 atttcttgta cttctacggg ctgtttcaac tctttgattt gttcatctaa tgtgatacct
    14581 tttcttttta attctggcaa aagcatcagg atctttgcga tgacatatgc accatcatcc
    14641 agaaaatagt tttccttgaa tgcagcgtgt ccgcttgttt cgatggctag ctgtgtatct
    14701 ttcccaagac ggttaagttc taatgcttta ttgattacat ttcgatagcc ggaaatataa
    14761 cgaacttgga tgcctccttt ttcttcaatg aatctttgta gatgagaaga agtaggggaa
    14821 ttcgtcacga ttcttgttcc tggatgctct tttaatacga ttgtacttaa tactgcgatc
    14881 aaattatttc gattgatcac tgttccagaa gcactgacaa ctgcagaacg atccacatct
    14941 gtatcgaaaa tgatcccaag atctgcttca tttgctaaaa cagcctgctt gatactttcc
    15001 atcgcttctt tattatcagg atttgggata tgattaggaa atcggccatc tggttccaaa
    15061 aattgggaac ctgttgaatc cgcacctaag ctattcaata ctttttcagc aaagaatcca
    15121 ccagcaccat ttccggcatc aacaatgatt ttccaaccat ttagtggttt gctttctagt
    15181 gttccaatcc cctttttaat ttttgtgact aaatcttgcg cataaggtgt caaaaggtct
    15241 gctttttcta cgcttccagt ttgttcgctt tttatttttt gctgctgtga taggataaaa
    15301 gcaatatctt ctttttctgc tcctccttct gaggtaaaga attttattcc attataataa
    15361 tagggaagat ggctagcagt cagcataacc gcagcatcgc acgagaactg ttcaaattga
    15421 gtggacataa acatagcagg cgtagtagct aattcgaaat cgatgacatg tatcccttgt
    15481 tctttcagac tttggatcaa cgcctctttc agtgctggtc cgcttatcct actgtcatga
    15541 ccaatcccaa tcgtccattt tttatttgga tcggttgatt tcttcttttt ctttatccag
    15601 tttgctagtc cccagccgat cttttttacc atgtctgtcg tcaagtttac ttcatatcct
    15661 tcaactggta atgcgattcc tcgaatatcc gatccatttt gcagcgcttt catatctttc
    15721 atataaaagt cctcctcatt tattccctca ttttttccag cttttctgca aatcgctgtg
    15781 cttcttcttc tgagcggcaa ataataatga atgtatctac accggccatc gttccgacaa
    15841 cttcagggta agccacttca tctagccaat tcgttaccac atcggcacca tttcgttcag
    15901 tcaatacgat aaccatgaac tgaacagact ggatacgcaa aacctcgcgt ctaattgctg
    15961 tacgcaaacg ttcttcattt aaagaaacag atggctggtt aaataatgta tagcgtacta
    16021 ttttgttttc attttgactt tttactaact tcatttctcg aatgtctcga gaaatcgttg
    16081 cttgagtcac atcggcgcct gcttcatgca gccgcgcaag cagctcttcc tgtgtcccaa
    16141 taggttgttc tgtaatgatc tggcggatca gtgcttgtcg ctgtttcttt ttcatattag
    16201 acacctctca atgttgatta tagcaaaaga taagtaatat ttcttcatat tttggtattt
    16261 tttactttta ttttttgttt tcattcaggt tgctaacctt tttctatttt aacacgcaaa
    16321 atcgtcttca ttttttcagg tgctgatttt cttggatcgc tgatgtaaat ctctttgtgt
    16381 tctttagaag ctctttcata gccttctttt gcgatgaatg cttctaattt ctcaaacgtt
    16441 gctggttctt cggcataggg cccgacgtgt aagatttggg cacaaagacc ttcttccatc
    16501 tttttgaata ctacttgttc tttcaagtct tccggaagtt tgctagaacg ctgaatggct
    16561 tcttgtgcta tcgcttctgt aacaaagtca ggctgtcgga tcatcaattg ataagaaaaa
    16621 tgttcttttt tcatcactgg ttcatgcaaa tacttttctt gcagtcccca ttgtccttcc
    16681 agtggataga cagtatacat ctgataatca ggaatcagcc aatttttttt aggcgacatg
    16741 cgtattgcat agctgactgc atatagacag gctactcttc gtttaaagtc ttcctgattc
    16801 gggtcgccga tccctctgat gctaaagaat gattttttag gaacctctag tatttgcggg
    16861 ctttttttca tactatagct cttgtcttta cgccattcaa ttttttccat ttttcttcct
    16921 ccgcgaaatt ccatttagtt atttattatc atacctcttt ttgagtgact tggctaatcg
    16981 tgttgacact atttttcagt ttgtgctaga ataagtgaag taaataaatc gtacagataa
    17041 cacgtttcgg cgtgtcgaga gagaggcggt ttctattttt ataatagaaa tcactctctt
    17101 tttttacgaa attttttaga ggtgatgtaa atgacaaaac aaaaacagct gcttttagta
    17161 cctgcagtaa ttgcaacagg gatgatgtct tttgcgggcg tattgatcga gacggccatg
    17221 aatgtaactt tcccaactct tatcagacag tttgatttaa cgactgcaca agtccaatgg
    17281 gtaacaacga tttatctttt gatgatttcg atcattgttc cgctgtctac ttatttgaat
    17341 cgcaatttta gtctcaaaaa actcttttta gcttcaaatc tgcttttctt ggcaggtata
    17401 atgatcgatt tcttctctcc taccttcatg gtcctattgt ttggtcgatt gctccaaggt
    17461 gcagcgacag gtatcgctct tccgttgatg ttccatatta tcttgacatt tgcccccctc
    17521 aatcgacgag gcgcgatgat gggtgtcggt actttgacaa cggccattgc tccagcaatt
    17581 ggccccactt atggaggcat tatgacttca cattttacat ggaatcatat cttcctgttt
    17641 cttgtgcccg ttttgtttct ttctttgatt atcggctggt ttgctattcc cgagatggca
    17701 gtacaaaaaa gtggttattt ggattggata agcgttttag gaatttgtct tttgtttagt
    17761 ggaagtctaa catttttgag tacgttggga acagtttcca gctggattgc tttaatcatc
    17821 ggcggtattg gctggttcct tttttactat cgaagtaaaa aagtggagca tccactgatc
    17881 cgactgtcta ttctttcaaa taaaacattc cgcttgtttt tgattggctt cttagtttat
    17941 cagtttttat tacttggtgt atcttttgtc ttgccgaatt tccttcagat cgttcaagga
    18001 agtagtcctt ttgtcgctgg attagcgatg cttcccggcg cagcggttgg tgctttgctt
    18061 tctccttttt ccgggaaaat gctggatcaa tatggtccga agaagccaat ttttgctggg
    18121 ctgattcttt ctttgattgg ttggctagca ttattcctac tcataggaca cgcttcagtg
    18181 ggtgtattga ttgcttgtca tgtgttttat atgatcggta tcggattatc ttacagcaat
    18241 atgatgacca ccggaatgaa tgcactgaat gaagaactac aaggagacgg gaacgcaatg
    18301 ttcaatacct tgcagcagtt ttctggcgct gtggctactt cattagtagc ggtcattatc
    18361 aattacgtcc agcatcatac ttcccataac tatgaagtgt ctactacatt aggatcaaaa
    18421 gcagcattag gcgtcttgtt gctgttgctt ctcgtaagct ttgctcgatt cgcctattat
    18481 ctgttctttg ctaaaaaagc gtagattcca tatacggcag gtgttgcatc tgccgttttt
    18541 ttgtgtgaaa atggttgttt gtaaaaggag gcttttttat ggaaaaaatt gccattatcg
    18601 gtggcgggat cattggtatg accctagcca gttacttaga tacatcaaaa ttcaatgttg
    18661 ctttatttga tgaagggaca ggacaggcaa ctaaagctag cgctgggatt atctcccctt
    18721 ggttgtcgaa acgcagaaac aaacaatggt atcgtctggc taaagacggc gctgcttttt
    18781 tccctaaact tataaaagat ttccaacttg atcaaacgat ttacgcacaa tcagggacac
    18841 ttttgcttcg acctgaaaaa gatttagctg aattggctgt tcttgccgag aaacgaaaag
    18901 aagaagcgcc agaaattgga aacatcgaat ggctttcacc tgaacagaca tctcaagcac
    18961 ttccgttatt gaaaccagca gtttcactgc gtatcagtgg tggtggtcgt ctggatggaa
    19021 aagcatattt agaacatctt ggtcagcgtt tagcacaaaa acaaatggag cagatccagg
    19081 caaaagtcac tttgcataag aagagcgatt cttggctcat caagggaccg tttggagaat
    19141 acacagctga tcgtgtaatt ttgacacctg gcccggcact taagccttta ttacaagaat
    19201 taggctatgc tgcagatata cgtccgcaaa aagggcagct cttagcattt cagacatctt
    19261 ataagatgag tcaagactgg cctgttgcta tgcttgacgg agaagctgat ttcattcctt
    19321 tcatggatgg aaagatcctt ttaggtgcta cccatgaaaa cgatcaaggc tgggatttgg
    19381 ctcctactag cgaagcttat aagggattga ctaagagtac agaacagttc ttgactgatc
    19441 cagatcagat aaaaaactgg ccatacgagt tccgtgtagg tacccgtgct tatacgtcag
    19501 atttttcccc atttttcggc gtactgccag atgatccaag cttactggct gctagcggtc
    19561 taggctcttc tggcttgacc acaggtcctt atatcggcta tctattagcc aacttcttaa
    19621 atactggtca ttggcctacg gaagattatc aaaaggacat ctccacctat attacgaaaa
    19681 atccatcata gaaaaacagc tttttcaagt aaggatcccg agcgatattg cgcatggatt
    19741 acttcttgaa aaagctgtta ttttagttca atttctgaat caaattctcc aaactttctt
    19801 ttgcttcatc tggcaagaga tcttttccta tctgagcttc aatgaatcgt aaacgaatat
    19861 caagtcgttg tttcaccaga tttttatagg acgtatcctc aaaagaaaca ggaaaatctg
    19921 gtataggtaa atagtggatg tcttcaaatg gaccaaacga cttgaattct gccgtttgtt
    19981 gcacgattct ttcaacgatt gacaatgtcg tttcaggttt gattttttta tcatcgaaat
    20041 atccagtatt caggacatag caggctgttt gctgtttcaa aaacaactct cgaaaagctt
    20101 gatagtcttc cctaagagga tagacacgga aaggattagc aaatggttca atgactagct
    20161 catctagctg tctttttgta gtgatatttt ccgcgtctga tcgttttgtt gctaatgttg
    20221 caccaaaaga cgctgctaaa actgggtcat tgatcttgat aattggcgga agcgaatcat
    20281 ctttcatgat ccaaaaaaca gcatcgatct tttcgctaag atgatcgact cggtcgggtg
    20341 tcgcataacg tgatttgact gtccgcccat ttccgtttcg tatatctcct gttactagga
    20401 ctttttctcc tttacttgta catgtcacgc ccacattctg acaagtaagg aaagaagaaa
    20461 tggccggatc atcagacgga tagtcttgtg ttttatcaaa gtaagaaggt tccaaggcag
    20521 tagcaaaacc attttttcga gaaataacga aagcatcgtc atgcaagatc gaaacagagt
    20581 gaccttccgt atgttttgct aaggtaatcg ttgattttcc agaaccggac aacccaaata
    20641 cagccatcgt ataggtctgg tcattactag catattgttt catcccaccg tggcaggcaa
    20701 taaagccatt gcgatttccc aatgcccaag caagcgtcaa agtcgctttt tttaattctc
    20761 caaagtaacg taatcctagc acagccgctg tattatggag agcatcaaac aaaatgagtc
    20821 catttggaaa tgtttcatgt gtccattcgg gatcacaaaa gatataaaga tctccctcat
    20881 caaaggaaac agacttttga taagtctcta agatcttcga attcgctggc tgaaaattca
    20941 gcaaataaga atacaaattg ttctcaaatc cttctggaat cagcaaatga ctttgcacag
    21001 aaaattcttc agataggcca acgattactt ttgtatggta aaactggcgc ttgcgacttt
    21061 gatacacagc ttctcttaaa attttctcgt atttgctttg ttccttgtct aagtcctcaa
    21121 agatccgccg agcacttgct gttcttccca caatgcttcc atcattgaat actagtgtcc
    21181 taacatcagc tggtaaatct agttcttcag catgtgagat tgttaaatct gtgatgatcg
    21241 ttcctggact cccttttgct agttgataag ctgtcttcct atcaaaaact tcatgaacat
    21301 tattaccgta aaatgtcgtt tctacaatcg atcgaatact ggataacagt ggatttccac
    21361 ttgtgatttc gtttaattcg agactctctt ttgtactcat ggctcctcct cattccctaa
    21421 acaaaaaaac gttttcttta ttatacatta ttcgagtttt tatttgtact gctgcgctgt
    21481 gggaagcaaa cgagttattt ttcacacaaa aaaaccgaga acttgaataa acaagtttct
    21541 cggtttcatc attttccttt tatcggctta gtaccagccg tttgctaacc agaatgtttt
    21601 agcagcatcc catgaaccat aacgagatgt tacatattgt tctgctacac gttcttgatt
    21661 ggcagctgaa tagtcgccgt ttaagtatga agcatctaat tgataacggc cgatgtaacg
    21721 tccgttagta gctgtgtatg aaccgcctga ttctttttgt gcgatccatt cttttgcaga
    21781 gcttgaagtt ggcgctgttg cagcagctgg ggcagcagga gctacttcaa ctgtttcaac
    21841 aggtgcaacg tatgtatgtt cttgcgttgc tgtttcagtt gtagatgctg tattttctgt
    21901 tgttttgttt tctgttgttg ctgaagaatc atttgaagtt gggattgtta attgttcacc
    21961 aacataaatg cggttgatgt ttgcgatcga atttttttca gcaattgcat cgatcattga
    22021 gttgtctcct gcaaattttt gtgagatctt agataatgaa tcacctgatt ttactgtata
    22081 aacttcatca gcgtgagcat ttgtagttcc tacaaacatt gcagtagcac cagcagcaaa
    22141 agttgtacct aaaacaattt tcttaaatga attcatatta aactcctttt tttctccgtt
    22201 ttttattctt tcgacgctat taactttatc atttagaaat atttcatagg taaaagaaac
    22261 atgaca
//
LOCUS       DACCVH010000043        22185 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.043, whole genome shotgun sequence.
ACCESSION   DACCVH010000043 DACCVH010000000
VERSION     DACCVH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.043"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            250..2085
                     /gene="tdc"
                     /locus_tag="IVV98_001680"
     CDS             250..2085
                     /gene="tdc"
                     /locus_tag="IVV98_001680"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP7807338.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2390..3868
                     /locus_tag="IVV98_001681"
     CDS             2390..3868
                     /locus_tag="IVV98_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7807339.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3834..5165
                     /locus_tag="IVV98_001682"
     CDS             3834..5165
                     /locus_tag="IVV98_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7807340.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5279..7831
                     /locus_tag="IVV98_001683"
     CDS             5279..7831
                     /locus_tag="IVV98_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAP7807341.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7838..9277)
                     /locus_tag="IVV98_001684"
     CDS             complement(7838..9277)
                     /locus_tag="IVV98_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7807342.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9623..9985
                     /locus_tag="IVV98_001685"
     CDS             9623..9985
                     /locus_tag="IVV98_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807343.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10172..11029)
                     /locus_tag="IVV98_001686"
     CDS             complement(10172..11029)
                     /locus_tag="IVV98_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7807344.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11149..12060
                     /locus_tag="IVV98_001687"
     CDS             11149..12060
                     /locus_tag="IVV98_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP7807345.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12067..13718
                     /gene="mdcA"
                     /locus_tag="IVV98_001688"
                     /pseudo
     CDS             12067..13718
                     /gene="mdcA"
                     /locus_tag="IVV98_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13820..14119
                     /locus_tag="IVV98_001689"
     CDS             13820..14119
                     /locus_tag="IVV98_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAP7807346.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14109..15785
                     /gene="mdcD"
                     /locus_tag="IVV98_001690"
     CDS             14109..15785
                     /gene="mdcD"
                     /locus_tag="IVV98_001690"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAP7807347.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15789..16382
                     /locus_tag="IVV98_001691"
     CDS             15789..16382
                     /locus_tag="IVV98_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAP7807348.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16406..17482
                     /locus_tag="IVV98_001692"
     CDS             16406..17482
                     /locus_tag="IVV98_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP7807349.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17507..18376
                     /gene="mdcB"
                     /locus_tag="IVV98_001693"
     CDS             17507..18376
                     /gene="mdcB"
                     /locus_tag="IVV98_001693"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAP7807350.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18487..19251
                     /locus_tag="IVV98_001694"
     CDS             18487..19251
                     /locus_tag="IVV98_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP7807351.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19740..21833
                     /locus_tag="IVV98_001695"
     CDS             19740..21833
                     /locus_tag="IVV98_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7807352.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21858..22160
                     /locus_tag="IVV98_001696"
     CDS             21858..22160
                     /locus_tag="IVV98_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807353.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7181 a         3789 c         4725 g         6490 t
ORIGIN      
        1 tcattttatt tgtttgttcg ctttttttag gttatctatt ttagaagact gatttattga
       61 aaaattgttc gcttttttgc gttgaattat cagaaaaatc cgactttatt tatttttgtt
      121 tgtaaaaatc tacgtggatt tgatgttata aaaaaaaaat tctcattttt ggcgctatag
      181 tgaagaggtg ttacagataa acacatgtat ctgcaagaca ttgaccaaca aaatatggag
      241 ggaagaaaaa tgaaagatat ggatatcaag gccgtcttta taggcgacaa agctgaaaat
      301 ggaccagttt ataaaatgtt gttgaacaag atggtagatg aacatcttgg atggagagaa
      361 aattatattc cttcagatat gcctgcaatt agcgaaggag ataagctcac tccagattat
      421 ctagccaccc gcgaccatat gatagaggtc ttggatgaag tcagtcagcg attacgcgca
      481 ggatcgatcc catggcattc agcaggccgt tactggggac aaatgaatgc tgaaacattg
      541 atgcctgctt tattagctta caactatgcg atgctgtgga acccaaataa tgttgcattg
      601 gaatcttcta tggcaacttc gcaaatggaa gcagaagtag gacaggattt tgcttcatta
      661 ttcaatatga cagacggatg gggacacatt gcagcagatg gttctattgc taatcttgaa
      721 ggattatggt acgcccgttg catcaaatcg attcctttag ctgtcaagga agtgctgcct
      781 gaaaaagtga aaaaaatgtc tgagtgggaa cttttgaatt tatctgttga agaaattttg
      841 gaaatgaccg aaagctttac ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt
      901 agcggaaaaa atatccaaag attagggaaa tggctggtcc ctcaaacaaa acactattct
      961 tggatgaagg cgttagatat ttgcggagtc ggcttagatc agatggttgc tatcccagtt
     1021 caagaggatt atcgaatgga tattaatgct ttggaaaaaa caattcgtga attagctgga
     1081 caaaaaatcc caattctagg tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta
     1141 gacagtgtag ataaaatcgt ccaattaaga gaaaggttaa aagatgaagg gatctatttc
     1201 tatttacatg ttgatgccgc atatggcggc tatgcgcgtt cactgtttct aaacgaagca
     1261 ggagaatttg tgccgtatgc ttccttagct gaattctttg aagaacatca tgttttccac
     1321 cactgcgtaa cgattgacaa agaggtatat gaagggttca gagctatttc agaagcggat
     1381 tctgtcacga tagatcctca taagatgggc tatgtccctt atgctgctgg aggaatcgta
     1441 atcaaacata aaaatatgag aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa
     1501 tcagtaaagg ctccagatat gttaggagct tatattttgg aaggatcaaa agctggagca
     1561 accgccgccg cagtctggac agcacatcgt gtattgccat tgaatgtgac cggatatggt
     1621 caattgattg gggcttcaat cgaggcagct caaagattca gagaatttct cgatcatctg
     1681 acttttactg ttaaaggaaa aacaatcgaa gtctatccat tgaatcatcc tgattttaat
     1741 atggtcaatt gggtattcaa agaacaaggc tgtacagatt tgaacgctat caatgaatta
     1801 aatgaaaaaa tgttcgatcg gtcttcttat atggatggcg atgtttatgg tgaacggttt
     1861 attacttctc atactacatt tacacaagaa gattacggtg attctccgat tcgttttgtt
     1921 gaaagaatgg gtctaacgaa agaagaatgg aaaaaagaac agaaaatcac tctgctacgt
     1981 gcggctatca tgactcctta tttgaatgat gatcgaattt tcaattttta tacaaaaaaa
     2041 atcgccaaag caatggaaaa gaaactaaac gaaatcatcc aatagaactg atttttgtgt
     2101 gaaagaataa caagagacat atggagaaca gacaattatt tgcttcatca aaacaattgt
     2161 atttccccct gtttttcata tattcctcgc caagatattc ttttttataa aacgttctat
     2221 aagttggatc gttcgtttca tgtatcaaac ccagttcact aagatcgttc aatggatgtt
     2281 tcggtgatac tgggttttgt actgaatcga tgaaaccttg tcatttctgt tcttgaacaa
     2341 aaataaaaga aaacaaaaac atatgtcgct attgaaagaa ggaataaaga tgaaagatac
     2401 tggttcatca aagcaaatca cgaccatgac ctttatcgga atgacctgcg cccttgtagc
     2461 aagtgtacga aatattccag atgtagcagc aacgagctgg acgatgattt tttacatgct
     2521 ggttgcagta ttattgtacg cttttccaat ctcattgatc tctggtgaat ttgctggaat
     2581 gtttccccaa aaaggtggtc cagaactttg ggtatcgaat gctctaggaa aaaaatgggg
     2641 gttcgttgtc tcatggctgt tatgggtcca aatgtttcct gggatggtga tggtcgcttc
     2701 agcactcgct ccgttgtttg gtaatattat cgataatgtg ccgcttggtt tgaacagcaa
     2761 atttacatta gttgtcattt tagtcgttta ttggatcatc acttttttga atttgaaatt
     2821 tgatatggca aaaatcggcg gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac
     2881 gatgatgctc ttattagggt ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac
     2941 attaggcagt ttttcatggg acaaattaat accagatact acgactgcat cctcatttgt
     3001 ttattttgcg ccgatcatgt ttatttttac tggtatcgaa atgtcctctg tgtatatcac
     3061 tcgattggaa aatccagtta aaacgtatat tcgcggagta tttgccgcgt taatttttat
     3121 atttttcgtc aatattttga atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat
     3181 ggaattgaat aatatcgcgc aatctatttc gatttattgc caaattcttg gtttgccaca
     3241 tcttattgtg aatctgttta gtttacttgt cttcattggt gtagcagtcc aattatctgc
     3301 ttgggcctca ggaccagcaa agacagtgac agaaagtgct agaaaaggtg cgtatccacc
     3361 aaaattcaat ttttggaaga cgaatcaatt tgacgtatcc aaatccgtta ttttgactca
     3421 gtctgtcatt atctcaatct ttgcactttt ttatttgctg attcctggcg tcaatcaagc
     3481 atttttgatg ctcgtaaatt caactactgt tatctactgt atcgtctatg tcatcatggg
     3541 gatcgcagtt ttgagattgc gttatacaca tgcaaagttg aatcgaccat ttagaattgg
     3601 aaaaaaagag aaaaagagca atcttggagt ttggactgtc gttattgttt tatttgcggc
     3661 aatcggattt tctgtcggac tgacgatgaa agctggaaca tggatcaatc taattgcagt
     3721 cacagccatc agtgtcattt tgtttgtagt accactctgt attgaaaaaa taaagaaacc
     3781 ttcttgggaa caggaagtcg ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa
     3841 aaccggcaat gaaacggact ctaactaatc gaaatatcca gttaatcgca ttaggtggcg
     3901 caattggaac aggattattt ttaggttcag caaaggcaat tgcatcagca gggccagctg
     3961 ttattctcgt ttatttgata tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg
     4021 atttattttt agcaaatagt acatttaact ctatcagtga tttcgttgac tattatttag
     4081 gcaaaaagtg ggcatttttt gtcaattgga cttattggct ttgctggctt ggagctggac
     4141 ttgcggaatt aacagcaata ggattgtata tccatttctg gtttgtacat gtaccagctt
     4201 tgataagcgg aggtagcgca ctaatgatct taatggcagt caaccttgtt gcagtcaagt
     4261 ggtttggtga attggaatct tttttctcaa tcatcaagat cttggggatt ttccttttta
     4321 tcttattggg tataggattg agtgtctcag attttcatac ccagtctatc ggaatcaaag
     4381 aaaattttgg acagatcgat gaattactac cgtttggctt tgctggaatg gtagtctcat
     4441 ttcctatggt tttattcagt tttgctggaa ttgaaatgat cggcttaacc gttggcgaga
     4501 caagtgatcc gcaaaagaat ttgaaaaaag caatcaactg tctgccttgg cgtattctct
     4561 ttttctatat aggaacgatt ttgtcgattt tatttgttgt tccatggcat tgtttagatt
     4621 taaaagaaag tcctttagtg actatgctgc aagtgatcca ttgccaaggc ggagcagcaa
     4681 ttgtcaatct aatgattttg gttgcttctt tgtcctcagc aaatagtgca gtctacagta
     4741 ctagcaggat tttatatcaa acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc
     4801 tttctaagaa aggcgtacct ttacacggta ttttaattac aggaatgtta ttttttgccg
     4861 gtctttgtct acattttttt gtagctgata gtcgattgtt ttttcagctt ttggcaggca
     4921 tgacaacgag ttgttttcta tttgtgtggt cttcgatctt gtgtgcacat gttcaattta
     4981 ttaaagaaaa gaaacggaac actacacaaa gatataaaga tcttgctttg ttggtgtttt
     5041 ttacttcaat tgctttcagc ttgttattcg aaagcacgac acgctttatt ccttttttat
     5101 tggttatctg gtttgtattc ttaaattttg tatataaaag aataagcaat agaaatatca
     5161 gttaggccca gatacatttt gcaaaacgaa ttatttcaga cccccctgaa ataatcgata
     5221 cgcctgaaaa aacttccctg cgtataataa cagtatcaat taaacaggag gggataggat
     5281 gaactggtac agattgacgg tagaagatgt attgaaaaac tatcaaacat caacagaagg
     5341 cttgtcgcaa gaagaacgac agaaacgcct gactgatcaa ggatataatg aaataaaagc
     5401 aaggcagcag acaaaacgat ggaaaaaaat agcaaagcat tttactgatc tgctgatgat
     5461 cgtgttgatc attgcctctt ttttgaaatt tgcttctagt gaatatattg aaggaagtat
     5521 tattttattc gtagtgatcg tcaatggact cgttagttac tggcaagaaa gaaaagcgga
     5581 agaatcattg aatggtttga agcagctgat gggacaagaa gcgatagtac tatcaaacgg
     5641 gatgcaagaa aaaatccctg cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc
     5701 cggagatgtc gttccagcag atatccgatt aatcgaagca catgatttat tagtggaaga
     5761 atcgattttg acgggagaat cagaagcatc tgaaaaaagt catgccgttt tgacagaaga
     5821 agaatcgatc ggcgaccaga aaaatatggg tttttcagga acgcttgtac aatctggttc
     5881 tgcagtcggt gtcgttgtag aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc
     5941 attgcaatcg gtcgaacaac aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa
     6001 acaaattttt caaggcattc tttgtttgag cctattctta gttattttta cgacatttcg
     6061 atatggtatg gattggcata tccttctttc ggctacgatt gctttggtgg tgtcaatggt
     6121 acccgaagga ttgccagctg ttttgaccat gattctatcc gttggagtac atgaaatggc
     6181 aaaagaaaag gcgatcatca aaggacttcc ttcggtagaa acattaggtt ctatgacagt
     6241 gatctgttca gataagacag gaacattgac aaaaaatgaa atgacagttg tggatgtagc
     6301 tgcaaaagaa gaagcctgcg tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa
     6361 agaagaacag aaaacagaaa atttaagtgg caatccgaca gaagttgcgc tgattcgaca
     6421 cacagaaaca gccaatctac ctttgaaaaa aatagaagca aagattccgt tcagttctga
     6481 atacaaatat atggcaacga tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg
     6541 tgcaccagaa gtattatttg ctaaatcaac tctttcttct gcagaacaag aagcatggag
     6601 tcagacagct gcagaatttg cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa
     6661 agtagattcg aaacaggaac tcacgcatga gactttaacc caattaactt ttgcagggat
     6721 cgccggattg atcgatccgc caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca
     6781 agcagggatc tcagtgaaaa tgattacagg ggatcacaaa gacacagcaa aagcgattgc
     6841 ggaacaaatt ggcttaaaac atactgccaa agttttagaa gggatcgatt tggatcttat
     6901 gtctgatgaa gagttgattc agcaagtgcc aatagtcgat gtctttgctc gaacgacacc
     6961 agaacataaa ctgcgaattg ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac
     7021 cggagacggc gtaaatgatg cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg
     7081 aatcaaaggt agtgaagtaa gcaaacaggc agctgatatg gttttaggag atgataattt
     7141 ccatacgatt gcaaaagccg taaaagaggg ccggcggatt ttggataatt tgcaaaaaac
     7201 catcaatttc ttcttgccaa ctgcattagc tcaaggattg atcttgattt gggcacttat
     7261 gctgaatcgc ccgctacctt tgtccccagt acagatttta tgggtcaata tggtaacgac
     7321 aatcacttta tcttatgcac tagggttcga gtcgccagat ccagaaatca tgaagcgccc
     7381 accaagagat ccaaagcaag gaatcctatc tggttatcat ttgtttcgga tcatctatgt
     7441 ctccctactg atcatggttc ctgcctattt attggctatg cagtttgaag ggcaaagctt
     7501 acagcaaacc attcttctgc aaaatatcgt cttagctcaa gctgtttaca tgatcaattg
     7561 cagagagttg tccaagccgt cattgaacca aggtcttttg caaaacaaag cgctttttct
     7621 ttcattaggt atccttgctt tattgcaagg gatggttatt tttctaccag tcggccagca
     7681 gctgatcggt acagtaagtt taacgatgac acaacagtta ttgattggag caaatgtgat
     7741 tcttctattc ttagttgtag aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa
     7801 agaaaaaaca gctagagaat acagtcgcta gccgttacta taaaaaagtt ttgaaagtga
     7861 gttcagtcaa acgattgagc tcatttttcg ttggaataga agaaatgtat acaataggga
     7921 tatctagaga atctagaggg aaattggaaa tcaagatatc tgttttttca aaagaaatag
     7981 tggaaagatc ggttagttcg ataggtaaga agcagacacg ttttcctaag taatctttta
     8041 attcctgctg caagaacgcc ttccatgaag gttctccttg gaaaataaaa tagacattga
     8101 acaaattcgg tttgatagaa aaaatcgttt gttggatcag tagagacaag agttggagaa
     8161 agtaatttgg ttcattgatt tctatttctt tttttagatc gttcagtaaa ttctctttct
     8221 gttgatacaa gtgtgcatat tgctgatcat atgtttctaa aaaacgatgg tattgacggt
     8281 ccaatgcttc aatcaatatc ggcgattcat gatattttaa tatgaggaga gccaagttat
     8341 cagtcagaga tgtttttttt agttgatcaa gagacagctc tgaagctagt tcctctacaa
     8401 acgtttcgag gacctctaaa aatggagaat gatgcaggca gcgagcggtt tcttgtccat
     8461 agttattgtt gtaattccaa ctttccagaa agcagaaaga agcaaaagaa agctcagtgt
     8521 ctttaagata aataccttcc gttaaataca attttttcaa tgcagagtca tacagggagg
     8581 agagtgtgct gttggtatgg atagaagaat ctaatcggca attcgctttt atacggatcg
     8641 tattgataaa gaaccaacat gttccgaaaa tctcttctgt ttcaaccgct agttcagttt
     8701 gactgaggtt tcttaaaaat tgaaaataat gggattcatg gatcgaataa tcctcgaaaa
     8761 aatagttgtt atgagtgaaa ggaatcagca atcgatgata aaaagtacga atcgcacgct
     8821 cttttccaag aatacaagct gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta
     8881 aacgctgatt gattttagtc acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg
     8941 ctagaaaatc agggacagca actttttttg taaaaagcag atttttcagc agttcgacac
     9001 tgactgattg tttgaaaaaa atctcccaaa ggtcatttgt taataaattt tgctggtttt
     9061 gcaaactgat tcctgcttga tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa
     9121 tagattgaag gtcagaaaaa atcgttcgtt cggttgtccc tatgatttca gctaattcat
     9181 ttacggttat ctttgtatga ttcagcaatt gttctactaa agaaacatga cgtcgaatat
     9241 ctttttcggt aatgattttt ttcattagtg aatacatcaa tcagactccc ttctattcta
     9301 agaatacgga gaaaataaac ggtggtcaag tttcaactga tttttcaatc attgtttatt
     9361 tttctggagc atttactgat gataagaatt tcatcatgaa cttgaaaaat gataccacta
     9421 aaatcaaaaa ataggtgggc aaacaataat aaacatttta atagtagatg gtagcaagac
     9481 caacacaggc ggattgaaca tttaagagtt gataaaaaag aaaaatatcg aagtatttga
     9541 ttagcaacta cttgtattca tttttctatt cttacgtggt atctttgaat aaagcgaatc
     9601 aataagaaag agatggaagc agatgctaac gaaaaaagaa ctaatcgatc acatcaatga
     9661 aacatacaat ttgtctccag aatatatttt taaaaaattt cctgattatt gcgtattcag
     9721 acatcaaaaa agcaaaaaat ggtttggggt cctgatgtct gttccagaag aaaaaatcta
     9781 tgatgatgca agtgaccata ggatcatcaa tattcttgat ttgaaggtcg atcctgaact
     9841 tggcggaatt ttgcgaggaa aagaggggta ttttccagcc tatcacatga ataaagaaca
     9901 ttggatctct attgatctac gtaaaataga aaagctagat gaactagcag atttgattga
     9961 tggaagtttt aaatcaacgc aatgaatgtc taggacaata gagaagaggt tgtgacagaa
    10021 atgtttagct tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa
    10081 atttcggctt attttctaag aaattacttc tggaacaccg tttgttcgaa aaaagagctg
    10141 cgacaagaat tttgtcccag ctcttttttt tttattttcc taaataaaat tcccgcatcg
    10201 tttttgcaat cattttgatc aaaggatgat cttctgtgaa gctagaagat aaataaattg
    10261 ttcgtgtcaa gggcaaatct ttgatttccc gcaagacgaa aggatcattt ttatcgtaag
    10321 accaagaaac ttttgggaaa aagctaacag ctaatccttg cttgacaata gaacgtaatg
    10381 tcgcaggatc atctgtcgtc gaactgatcg tcaattcgat acttttcgct tcaagtgctg
    10441 catccagtgt atgacggaag gcgttgctct ttgacagcat caagatgggg gtgcgttgga
    10501 tatcttctaa ttgcagatgt tcttttttag caagaggatg tttcttagga atggcgacat
    10561 aaacaggttc tttcatgata ggaatattgg tcatgccagg cttcatctcc gaagtgatgt
    10621 acagtacagg atcggtaata tcatctggta aatgatgttg catgatcgtt aattggatat
    10681 caggatgctt ttccataaaa attcggacca agttcggaat agaaacagag gctacctcta
    10741 aatacaatat gacggaagta acgatcttct cattgaccga agacaataat ttgattcctt
    10801 cttctaatgt gtctaatgtc ttgactgcat atggataaaa ttcttctgca taaacggtcg
    10861 tctcaatgtt tctgccgcta tggtaaaaca aagggacacc taattcgttt tccaaatgtt
    10921 tgatcgcacg gctcaaggca ggttgagaaa taaataattc tttggctgct tgggtaacat
    10981 tttttgtttc gaatactttt ttaaaatact gcagatgaag caatttcata attatccatc
    11041 ccatccatac ctttttgtta tggttttttc tttttttggc attttttatt atagcagaaa
    11101 ttgactaaga tagcagtgga aaaagtaagt gctgaggagg cgaggctcat gagtacaggt
    11161 ttcttatttc ctggacaagg cagtcagaag ttagggatgt tagcggatat ccctgaaatg
    11221 tacatggaac gtttagaaaa tgtgacgggg tatcggttag ttgataaaga agaaaactat
    11281 caagatacgg tttttatcca gctagcatta ctgacaaaag cagtatttta tttagatgaa
    11341 atggaaaaaa acggtattca gcctgatatt gcagcaggac attcgattgg tgctttttgt
    11401 gcagctgttg cttgtcgatc tttgagattt gagaatgcag cggaactagt ctatcaccgc
    11461 gcagtcttaa tgaaagaagc ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg
    11521 acgagaagcg aagctgagga aattgtagca aaaacatttg atcctgacca tccagtttat
    11581 ctgtcaaatg aaaattgtcc gatgcaacat acgttatctg ggagtatcga aggtttatcc
    11641 gttacgttgg cagaagccaa acggcaccaa gcgcaaacag cgaagctgct gaaagtccct
    11701 gtgccatctc actgtctctt gatgaatgat acggtcaaga aattcaagcc gtatatgcag
    11761 tctgtccatc tatctgatgc tagatgtttg tatataaaaa atacggatgg aagagccact
    11821 caggacgcag aagagattcg taaagatttg ttggaaaacc tagctttccc tgtgcagtgg
    11881 aaccaaatga tggacttggc aaaagaatta ggaatggatc tgacgattga atttcccccc
    11941 ggcaatactt tgacaaagct gattcataca aaatttggtg tagataaagg gatccgtacg
    12001 atcaatctag accaacatgg tattgatgac gccacgtttc tatatcaaaa atggagatga
    12061 ctaattatgg aaaaaccaaa ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga
    12121 ttggaaaaaa tcagcaactt gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa
    12181 gtaatggaaa aactgattgc tcccggcgac aaagttgtat tagaaggcga caatcaaaaa
    12241 caagcaagtt ttctttcaga aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg
    12301 catttgatca tgtctagtat ctcacgacca gaacatttga atatttttga aaaaggaatc
    12361 gcaagcaaga tcgatttctc ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt
    12421 gaagacggca caatgaaatt aggtgatatc catacttatt tggaacttta tggacgctta
    12481 ttcatcgatt tgattccaaa tgttgtttta gtagctgcag ataaagcaga taaagacggc
    12541 aacttgtaca caggtttcaa tacggaagaa acaccaacaa tcatcgaagc tgcagctttc
    12601 aaagatggta tcgtgatcgt tcaagttaac gaagttgtcg attctttacc acgtgtagat
    12661 atccctggtg actgggtaga cgttgtcgtg aaagcagata aaccttatca attagaagct
    12721 ttattcacac gagatcctca aaacatcaca gaattgcaaa ttctaatggc aatgatggca
    12781 atcaaaggaa tctacgcaga acacggcgta caatctttga atcacggtat tggattcaat
    12841 acagcagcta tcgaattgtt actgccaact tatggtgaat cactagggtt aaaagggaaa
    12901 atcgcgaaga actgggtatt gaacccacat ccaacgatga ttccagccat cgaatcaggt
    12961 tgggttgaaa gcatccatag ttttggtggc gaagttggta tggaaaaata tattgctgct
    13021 cgcccagatg tcttttttgt cggtaaagac ggcacgatgc gcagtaaccg aacattatca
    13081 caagctgcag gacaatatgc catcgatatg tttatcggtt caaccttgca attagattac
    13141 gaaggaaact cttctaccgt aacaaaagga cgtttatctg gttttggcgg tgcgcctaac
    13201 atgggacata atcctggcgg tcgtcgtcat tctacaccag catggcaatc acttcgcgac
    13261 aatgatgatc cattagggaa aggccaaaaa ttagttgttc aaatggttga aacatatggt
    13321 tcaaataaaa aaccagtctt tgtcgaagaa ttagatgcac tagctgttca aaaacaagca
    13381 ggcttagcca atgcaatgca ccagtgatga tttatagcga agatactaca catatcgtga
    13441 cagaagaagg aattgcttat ttgtacaaag caaaaacaaa agaagaacga caagcagcaa
    13501 ttgcagcaat tggcggtgtt acacctcttg gaatgactag cacgaaagaa tcactagata
    13561 gcttgcgtgc agccggcatc gtgaaattac cagaagatct aggcatcaaa cgtagtgaag
    13621 cgaaacgttc attattagct gcacaaacca tcgatgattt gatcgaatgg tcagatggcc
    13681 tgtatgaacc accaatgaaa ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg
    13741 tcgccattta cccagatgga agaagaaaga cgaataagca gaacgtgtat gctctgtttt
    13801 acaaaaaggg gagagatcca tggaacaatt agcttataaa tatccaacga aacagccgat
    13861 caataagaaa atccatgtag gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc
    13921 aacagaaaaa acagaatcta ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt
    13981 atggaacaat gtattaacga gattttttga tcgttatcca atttcagcag atatcgtgat
    14041 caatgacttc ggtgctacac caggagttgt gtacctacga ttgacgcaag caatggagga
    14101 actttcagat gaaaaatagt tttgtagaat taaacgccag agaacgagtg aacgctctac
    14161 ttgacaatgg acgtgaattg attgatccat tcgatcaaat catcgcgcca agtttaccag
    14221 cacaaggaat cgtccctgaa agtgatgacg ggatcgttgt cagccgtggc acgatcaatg
    14281 gcaaacaagc agtagtaatc gctatggaag gaaaattcca aggtggcggt atcggtgaag
    14341 tttccggtgc aaaaatcgtt gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa
    14401 atgagatctt tccagtcatt gtactagata caggtggtgt tcgtttgcaa gaagcaaact
    14461 acggactgtt atctatttca gaaatcggaa atgtaatcat tgctctaaaa caatatgtac
    14521 cagtcatcgg tttgattcca ggacgtgtag gatcatttgg cggtatgtcg attacttcag
    14581 cattaatgag ttatttaatc gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag
    14641 ttattgaaca agaagcaggc gttcgagaat ttgattctag tgacaaagac ttgatttgga
    14701 atacattagg atctcgtcaa cgggtagaat caaaaatcat tgatgaatta gtgactgata
    14761 gtgtagaagc aatcaaagct gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc
    14821 gcagtgaaag ctcagcattt tatttatcat tacttgattc tttagatctt tcaaaaccaa
    14881 tggccattga cgattacaat gaagcaattg ctaaccatca agcaaaatca attgacttac
    14941 cagaagtagc agaaggaaat gaaccagctg cagcaagtgt tggttacgat tggtttgcgg
    15001 cactaactgg catgaaaaat ccaacttctt ctattagtac tgtgtattat ggtaaatcaa
    15061 gtaaattcat agaagaagcc atcgtgacat caatcgtacc tgatcctaaa aacccgatgt
    15121 accgtgtacg aaacggtgaa gttggtttag ttgaaggttt ccgcatggga caaattttgg
    15181 atcacgttta cgaagaagat aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg
    15241 atgtaccaag ccaagcatac ggctataacg aagaattgat cggtatccat gtggctttgg
    15301 ctaatagtgc tgctgcttat gcaaaactcc gtcaagctgg acatccagtt attggattga
    15361 ttgcaggaaa tgctatttca ggtgcatttt tagcacatgg attacaatca agccgcttga
    15421 ttgctttaaa caataaagaa attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg
    15481 tgacaaaacg ttcggttgct gaaatcgaag cagctgctga aaaagttcca gctatcgctt
    15541 acgatatcaa taattataca aaactaggag cgatctatca tttcctagaa gatatcaccg
    15601 accaagctgc ttcagaacaa aatgtcagca aagtcatcga agcaatcaat gaagccattc
    15661 aagatgtccg caatacaaat gacacgatgc tgacaaatcg atacacaaac gaaacagcca
    15721 aaacattcgg acgtgtcgaa acaaataaag tccgtgccaa aatggacgaa gaatgggatg
    15781 cataaaaaat gattcaagca catgatattg tcctttttga taaacatgaa atagaagggt
    15841 tcaccttgcc tgaatgggtc gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt
    15901 cgacggatca cgcagaaata ctaccgattg gtttacgtgg acctgcccgc aatcagagat
    15961 ggtcaacaga aatctcaaaa catgccgtca aacaagtcat tcatccgtgg gacatcatcg
    16021 aacaagaatc gtatagacaa gagaaaatca tggattatcc tgtttatcag caatttcatg
    16081 ctgctagaaa catattatca ggatgtaaat ggggaatcgg cggcagctta ggatttgaat
    16141 tatcgactgg gattccggca gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa
    16201 attcaccgat tgaattgcca attcaggtaa ttcaatcgca tcctgctttt tttgagcaat
    16261 tcgataccca agtagtgact cggcaaggcg gtttttcact aaaagagtat ttgagagagc
    16321 cagagaaaaa aattctattg aaaacagtcg aaggacctaa attaaccaaa gaactttggt
    16381 aataaagaaa aagagagaga aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag
    16441 tgacttccag aaagtatcag ctgtaacggc tgttatgatg caaacgatat tgagctttgc
    16501 tttggcaaac agccacagcg caacaaatac agcttttctt ggtacctttt acgtcatcgt
    16561 taaatacaca gcaccaatgt ttatttttgc aattgtttat aatatggtaa aaacaagtca
    16621 gcatttgtct tattgggaat ttttgaaaga aaagtttttt gaactagtcg ttccgtatct
    16681 tctatggacg acggcttatc tttggctatt tccagcagtc caacaacaaa ctccgtatac
    16741 ggatactgca agctttttac tgaaatatgt cacaggtgat ggagcgcctc atttatggta
    16801 taccgttatg atgctgcaga tccaattgtt catgccgttt tttgtttggc tcggttacaa
    16861 agtatttgct aataaaaaat atgtatggcc agtattgatt ggttcaacga ttttatatgt
    16921 cgcatggtat ctgttctatc aaacacaagt attgactggg ccttatcatg acagctggta
    16981 cttattagat cggtttgttg ctagtttcat gatttatggg gtagccgcat ttgtttatca
    17041 cgaaaaagtc tatcaatatt tggacagagt acgttatctt ttcttacctg ttgccttagt
    17101 tatcgcgttc ttttctgtcc gttcattgct cgcacatcca ggagacttga gctttgcgaa
    17161 tgcaccttac ttgaatacga tccaaagttt atacagttta gtcatcatct ttgctgtctt
    17221 cataggcgct tccaaaatga ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt
    17281 gtctgtttat gcttatcgta cgtatttagc caatgtattt gttttccaag tactgttatt
    17341 attgtttaaa gatagttggc tgcagttacc ttcaggagtc atgattcttg tagcttatct
    17401 aatgacggca agttgtgcat ttgctttaag ctggttactt catatcattt gggtagctat
    17461 caaaaaaggt ttcagcaagt aatagtagga agaaggagtg agtgtcatga taaatgacga
    17521 acgaaaaaaa gcagtgactc agcaactcgc tgcgttggta gaggaagcat tgatcgcaga
    17581 agtaacatta agtccaaaac ctggattagt ggatgcactg gatgcgggtg cacattccga
    17641 tatggactat gctttatttc ttaagtctgc taagacgcta actccttttt ttgaagaaat
    17701 ggctcaaata gcatggcatc atgctattga tcaggagtta agagaaagaa ttgctgagat
    17761 tgggcgaaaa gcggaaaagg caatgctgat tgctacaaat ggcatcaata cccataaagg
    17821 agcgatttgg gcaatggggc tattgatcag tgtcattgca caaaaaatca gtatggaaca
    17881 gcctttttct ttatcgaaaa tacttgatga tgtcagcaag cttgctgctt ttcctgatac
    17941 aaaatatcgt cataaaaaaa ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa
    18001 tggtgcatat gaagaagcga tattagggta tccgcatatc aggcttgcaa ttcaagcagc
    18061 taaggagcta gataatgatt catatgtaca gaaacaaatg catatgttgt tagttttgat
    18121 gagttcgcta gatgacacat gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat
    18181 gcaaaaactt gctcatgctg ctagtcaaag tgctttacca aatcgtccat ttacagcact
    18241 gttgcacttt tgtcaggaaa accaaatctc tcctggagga agcgcagatc tcttgtctgc
    18301 aagcttgttc atgctgaaga tagaggaatt atggactgcc gacacataca tttgtccgat
    18361 gttactcaat gactaaataa gacaaaattg ctaaaaaaac agtttatgca tctggttatt
    18421 gactcttcct tttagcaagg ctatcataaa aatagttttt tgtaataaaa gataacgagg
    18481 aagacaatga aaaaaatcaa ttatttagca atcattttgt tagtgggcct atgtttgttt
    18541 gctctgccga cccaaggatt cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt
    18601 cgaagttcgg gcagaggttc atttggtggt cgttcatatg ggggcagtta ttttggcagt
    18661 cgttcttacg gcagagattc ttatgggtat tatggtccag gtacaggtcc ttctagttat
    18721 gagcaaacgg gatttcttgc attagctgtt ttgtcagtag gaggggtttc tgctttttct
    18781 atcgtcaaga ataaaagaca aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca
    18841 ggaacggcta aagaaaagaa agcacagttt ctggaaatcc aaaagatatt catgaagatc
    18901 caatccgctt gggaagaaga aactcctgaa aaagccagaa gctgttatac agacaagctg
    18961 tttgccgaac atcagaaagt tctgcaaaaa aacaaagcag acggtgtaag aaatcatact
    19021 aaaaaaataa ctattcagga agtaggaaat tatcgacaga tccacgaaaa tagttttgcc
    19081 atccgaattg atttcagatg ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc
    19141 tcaggaagta agacacaacg acagtatttt tctcagatat ggtattttga tttttctgag
    19201 aaagaaaaaa gatggcaagc cgattttatt cagccgatta tgctggattg acaggaaata
    19261 tttatgaacg gagttgtgac aaaagccttg tcgcagctcc tttttctgaa taaacggtgt
    19321 gccagagata gcctatcggc aataaggcac gattttgtaa aatatgggaa gcgatttttc
    19381 aaaatcgctt cttatcgctc aaggctgaac atctctgtca caacctctcc actaaatggt
    19441 gtttaaaagc ttgcatctgc gataataaga acaaccaaac gaaaaatagg aagcactatt
    19501 ttagtttagt tgttcttatt acttgatgca ggacagcttt ttcacaacct cttttttgta
    19561 tagatgggca aaatttttgt aataataggc gtatgtcttt ttcgttgagg agatgaaaaa
    19621 gcatatggct tattttttgt ttgctttgct tactttcttt ccacttcaag tggcagaaat
    19681 atctactttt tattatgtaa gcggaaccat atacttgaaa tcagaaggag atcatttcta
    19741 tgaaaacaag aacaattgaa atacttcaca gaatcatgac agcccaatat ccagtaaaag
    19801 caaaacatct agcaagtgag ttcaatgtca gtcagcggac gatccgtcag gaagttcttg
    19861 aagcgaatat ctggttgagc agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag
    19921 gttttttgtt gaagctggaa aaggaaaagc aagctcgatt agaaactgaa ataaaagatg
    19981 tgaaagacgg ctttttgaat cggcgcgaac gtatttttga tctagtttta gccgttgctt
    20041 acagccgaat cccgatccat ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta
    20101 cattagatga agatatgaga cggttacgag caacactggt cagttatggg atagagatcg
    20161 tcagttatgg aaagcaagga ctggtttata aaggttcaga acgatctatc cgtacgatga
    20221 tctatgattt tatcaatcag aatctgggaa tgaccgactt ctttatgaat caagatgcac
    20281 aattaacacc ggctcaaaaa atctttctcc attattttcc tttggtggaa atcaaaaaaa
    20341 tacaggagat ctattccaat aagttgttga aacaagaaga tgatatttat aaaaaacaaa
    20401 tcctgctttt tacattgatc tggatccagc gaatcaggaa acatgaattt atctctgcca
    20461 ttaattggaa aaatacagaa ataaaagaca gtagcttttc tgcatttatt gaccacatga
    20521 tcgaggaatt tcaattggac aatgtcccgc aagtagaaag aaattatctt cgtttcacta
    20581 ttgagacgtt caatgctaga gatatctcca attcaatcga gtgggtacaa gctcaattac
    20641 taacgatcca attgatccaa tttgtagaga acgagacaca cgtacctttc catctaaagg
    20701 aagaagcttt attcgaaaat ctctataagc acatggctgc actgattgta agaatcaaga
    20761 atcatatcca agtcatgaat ccattgaaag aaaacatccg aacaaattat ttcccaatct
    20821 accgcgcagt cactcatttt gttcctacga tcgaagaagt aattggtggc aagatactgg
    20881 aggacgagat agcttttctt gtcatccact tttcgacgat cgccagtgta atcaagcgag
    20941 acttgaatta tgtttataaa tcagtcgttg tctgtaacca tgggatggct actggaaatc
    21001 tgttagcaga gaatctgaaa gaaaagtttc ctcagatcga gattactgca gttttaagtt
    21061 caaaagaaat cgaattagta gataaattgg atgtcaatct ggttttcagc acctttcaat
    21121 tgaattatcg aaataagccg cttttagttg tcgatccgat tttaactgag acgaatatct
    21181 tggttataga agactttttg aaaagaaatg aagaactaca gcggttagag cctaacagtc
    21241 atgaatcgac ggagttattc actcaaataa tagatgtcat gaaagaaagt ggtggccgag
    21301 tagatcgaat catctatggc aagttagaaa aattattcga aacaaacaat ttagaaatca
    21361 acaaaaggga gatccagcct atgttaaaag atattttgac ggacagcaat atcatgatca
    21421 aagaaaaagc cactacttgg gaggaatcga ttgaactagc tgctagacca ttggttaaag
    21481 aaaacattgt cgaagagcgc tatgtcgaag cgatgattcg tgcagtgaat gattacggac
    21541 cgtatatcgt gattggcaaa cacatggcac tagcccatgc ccgaccagaa gatggggtca
    21601 ataaattagg agtcagcgta gctacgattg agcaaccaat cgatttcggt aatcctgaaa
    21661 tggatccagt aaagattatt ttttgtttgg cagcagtaga ctcctactcg catctgaaca
    21721 tcatgaaaga actaattgaa ttgatcaaca acgaagagaa gttggatcga ttgattgaat
    21781 gcacaaatat cgaagatttc aaacaactgc ttttttcagt agttgagaaa taataaatga
    21841 tacgggggag aacaaagatg aacaaattga acattttatt cgtatgcggt gcaggtttag
    21901 gaagtagttt tgcagcacag atgtctgctg aggatgtttt gaacaaatta ggagtagaag
    21961 ccaaactgga ccattgtgat atttcttccg cagtttccat gaaaccagat gtgatcatca
    22021 cagcagaaaa ttttcgttcg cagttcgaaa agttcgcagt tgatcctaaa acggcgatga
    22081 tctatttgaa aaatattgtt tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc
    22141 aagataaggg agttatctaa atacaaaaag aaaagagggt aaaaa
//
LOCUS       DACCVH010000044        21855 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.044, whole genome shotgun sequence.
ACCESSION   DACCVH010000044 DACCVH010000000
VERSION     DACCVH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.044"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            104..1621
                     /locus_tag="IVV98_001697"
     CDS             104..1621
                     /locus_tag="IVV98_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP7807354.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            1611..2882
                     /locus_tag="IVV98_001698"
     CDS             1611..2882
                     /locus_tag="IVV98_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7807355.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            3057..3953
                     /locus_tag="IVV98_001699"
     CDS             3057..3953
                     /locus_tag="IVV98_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807356.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            3967..4830
                     /locus_tag="IVV98_001700"
     CDS             3967..4830
                     /locus_tag="IVV98_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807357.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            4836..5400
                     /locus_tag="IVV98_001701"
                     /pseudo
     CDS             4836..5400
                     /locus_tag="IVV98_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            5410..6933
                     /locus_tag="IVV98_001702"
     CDS             5410..6933
                     /locus_tag="IVV98_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP7807358.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            6945..7904
                     /locus_tag="IVV98_001703"
     CDS             6945..7904
                     /locus_tag="IVV98_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP7807359.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            7990..9069
                     /locus_tag="IVV98_001704"
     CDS             7990..9069
                     /locus_tag="IVV98_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807360.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(9321..10742)
                     /locus_tag="IVV98_001705"
     CDS             complement(9321..10742)
                     /locus_tag="IVV98_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010580899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP7807361.1"
                     /translation="MLEGENTYEKRKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFL
                     QHDWGLAGKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLS
                     ASAPHNGSYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGML
                     LSYVADYLLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRV
                     LNYIRTPKEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGA
                     NAIFYYIPLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGS
                     VMGLSFILPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRG
                     RASGLASSFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGK
                     SLEEIEQSASKKTYPKRISIHHS"
     gene            10938..12599
                     /locus_tag="IVV98_001706"
     CDS             10938..12599
                     /locus_tag="IVV98_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP7807362.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12556..13254
                     /locus_tag="IVV98_001707"
     CDS             12556..13254
                     /locus_tag="IVV98_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP7807363.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            13270..14694
                     /gene="araA"
                     /locus_tag="IVV98_001708"
     CDS             13270..14694
                     /gene="araA"
                     /locus_tag="IVV98_001708"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP7807364.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            15001..16161
                     /locus_tag="IVV98_001709"
     CDS             15001..16161
                     /locus_tag="IVV98_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAP7807365.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            16279..18138
                     /locus_tag="IVV98_001710"
     CDS             16279..18138
                     /locus_tag="IVV98_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7807366.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            18248..18682
                     /locus_tag="IVV98_001711"
     CDS             18248..18682
                     /locus_tag="IVV98_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807367.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(19121..20143)
                     /locus_tag="IVV98_001712"
     CDS             complement(19121..20143)
                     /locus_tag="IVV98_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP7807368.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            20271..20624
                     /locus_tag="IVV98_001713"
     CDS             20271..20624
                     /locus_tag="IVV98_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP7807369.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20636..21802
                     /locus_tag="IVV98_001714"
     CDS             20636..21802
                     /locus_tag="IVV98_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7807370.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
BASE COUNT         7116 a         3726 c         4639 g         6374 t
ORIGIN      
        1 ggttaattaa aatcgataaa aaataagtaa gtttaacatt tatattattg acaacgcttt
       61 caacgaggtg tattattcat gtataaatta aaggaggtca gttatggaag ccacaatgtt
      121 gattagtagt gtcaagcgtg taggcaaagt tgatccgcgg ttgtacagtt catttattga
      181 acatatggga cgagcagtat atgaagggat ttatcagcca gatcatccat cagctaataa
      241 aagtggattt cgccaagacg tcattcactt ggtaaaagaa ttgaacattc ccatgattag
      301 atatcctggt ggaaattttg tgtcaggatt tcgttgggaa gacagtattg ggcccatagc
      361 aaatagacct agaaggttgg atttagcttg gcggacaatt gaaacgaatg aagttgggat
      421 tcatgaattt tataactggt gtcagcatgt gggggccgaa atcaatatgg ctgtcaatct
      481 gggtactcgt ggagtagatg cagctcgtaa tttagtcgaa tattgtaatt ttcctaaagg
      541 aacttattgg agtgatttaa ggcgttcgaa tggtcaagag agcccttttg gaattaagac
      601 atggtgttta gggaatgaaa tggacggtcc ttggcagatt ggacataaaa cagcggaaga
      661 atatggacgg ttagcagagg aaacggctaa ggcgatgaaa ctcgtagatg attcaattga
      721 ggtggtttta tgcggaagtt cgaatcggca aatgcctaca tttggtgatt gggagttaac
      781 agttcttgat caagcgtacg atcaaataga ttatttgtct ctgcatcaat attatggcaa
      841 ccaaaaaaat gatctttctc attatcttgc acgttcctta gacatggatc ggttcatttc
      901 tgaagtgaca gcgatgtgcg atacagtcaa ggcgaagaaa catagtaaga agcagatcaa
      961 cctgtccttt gatgaatgga atatttggta tcattcagcg gaacaagatg agcaagcagc
     1021 gccttggcag attgctcctc ctttactaga agataactat aattttgaag atgcattact
     1081 attaggctgt ctattaatca ctttattgaa acatgcagat agagtaaaga ttgcttgtct
     1141 tgctcaattg gtaaatgtta ttgcaccaat caggacagaa acaaacggag aagcttggag
     1201 acagacgatc tattatccat ttatgcaagc tgctgtgtat ggacaaggag aggtgttaag
     1261 cccacaaatt cgttcagcaa actatgcgac ggaagatttt gaagaagtgc cgtatttaga
     1321 aagtatagcc gtaataaatg acaaagaact tgtcatattt gcagttaacc gtggagaaga
     1381 agaaatgaat ctaactgttc acttgtctga attatcatta gagggagtga ttgatttttc
     1441 tgaaatgagt ggatttgata caaaagcaac taatcttcct aaaagtgaac aagtaaaacc
     1501 aagtcattca acaaatgtaa aagctgaaga tgggaaaatc aattgtttat tgaaaccgct
     1561 atcttggaat gtggtcagat gtcgtttatc agatgaagga ggaacaaaaa atgaaaggta
     1621 aaaaatggtt aattggctct ttgttggtag ctgcaacagg tattttagga gcttgcggtg
     1681 gcggaagttc agcagaatct gattctgata aagaagtgac tttgactttt tggaatgggt
     1741 ttactgcatc tgatggtgaa atattgcaag aaatcgttaa tgaatttaat aaaacaaatg
     1801 ataaaaacat caaaattgaa atggatatca tgacttgggc caatttgaat gaaaaacttc
     1861 ctacagcgat ttcttctaaa aaagcacctg actttattgc attaaattat ccagattttg
     1921 cacagtatgt agaaaacgga gcggtacaac cattagacga tttctgggaa tatgatggag
     1981 tagataaatc tgattttaaa gaaacggcta ttgaattagg tgaagtagaa ggtaaacagt
     2041 attttgtccc catgcaggta caaggcatgt atatgtattg gaataatgat ttgtttaaac
     2101 aagctggatt agatactgaa caaccaccta ctacttggga agaattgaca gaaatggcac
     2161 caaaattaac tgatagtagt aaaaatgtat caggttttgt cttcaataag gatggaactg
     2221 caccgttata taactggatg ttagcaaatg gcggtaaatt agtgaacgat gattatacta
     2281 agtctgaatt tgcgtctcct gagaacctta aaacgttaaa agcgatccaa aaaatgatcc
     2341 atgtagacaa gactggtcca gaatcgattt ctggcgccga aatggacaat ttaatgaatg
     2401 ctggtcaact agccattgaa atcaatgggc catggttaaa taacggattg aaagcaaacg
     2461 agattgatta taatgtgact accttaccac aagggagtga ttcagacaaa aaaacagcta
     2521 ttttagatgg cgtaggatat gccattccgg caagtacaga taataataaa aaagaagctg
     2581 tctatgagtt tttgaaatat tggaatacaa ctgaaattgg taaaaaatgg agtatcgaaa
     2641 atggttttcc tgcctacttg gattcagtag caaaagatga agaagtaaaa aatgatccta
     2701 ttgtatctga attatcgaaa caaatggact atgcagagcc atatttacca ggttttaccc
     2761 aaatctctgc gatcaataac gatatcatca atccactgat tgaaaaatta ttagcaggag
     2821 aagatcctga gacactcatg aacgatgcag atgatgccat caatcaatta ctgcaaaaat
     2881 agtacagaac tttatacagg atagactgtt ggcaagatac agatatctga atgatcgacc
     2941 tagtatttgc agataggtgt tattgcaaaa atcacagcga ttgttcggat atcttattca
     3001 gattcgttta aaccaagatt gtatatttta tcaaaatgaa agatgaggtg gactatatga
     3061 acggattcac caaatattgg aatcgtcctg atcgtgctgc gtatttgttt ttaactccat
     3121 cttttttagt tttattatta tttactgtca taccgctttt aggaacattt gctattagtt
     3181 ttacagattt gaatattttc tttacatcaa gaaattttgt aagttttgaa aatttcacac
     3241 gtatatttag tgatgaacga gcagttaatt cgttgattca ttctttatat ttcaccgtac
     3301 tcgaaacgcc aacacaaatt atcgttggtt tattagcagc agtagcatta tctaaaaata
     3361 ccagattcaa tcgtttttgt cgttcgacat tttacattcc agttatttgt tcattgacgt
     3421 caattgcgat tattttttct atgttgcttg atccgaatgt aggggcgatt ccttacttgt
     3481 tttcacaagt cggcttgccg atccctcaat tttttcgcga tccaaccctt gctatgccga
     3541 cggtagccat catgactgtt tggaagaatt ttggtgttac tatgacgatt ctcttgactg
     3601 ctattcaggg aatctctccc tctttgtatg aatctgctca aatggatggt gcaacaaatc
     3661 gacagcagtt ttttaacatt acgctacctc agatcgttcc ctccttaggt ttttgtattt
     3721 taacgaatct gattggttcg atgcaagtgt ttgaccaagt atatgttgca accgctggtg
     3781 gcccacaatt taagacagaa acagctgttc aatatattta cagtcgagga tttacagcac
     3841 cttatgaatt gggctatgca tcagcactgt cttcggtttt gtttatcatt gttgcaacta
     3901 tagctatctc cactaatgtg tacatgtcac ggaaagaaaa acaaatgaaa taggagggaa
     3961 acctgtatgg caccagaaag ctcgattaca gttactgtga atagtcgaaa agcagttagt
     4021 ggtaaaaaaa tcattcgaac gattagtatg ctagttatat tgttggttat tgcgtttcct
     4081 tttttgtggc tgattatttc ttcttttaaa cacgaaaaag acattatctc atttccgcct
     4141 agaatatttg cagatagcta taccctagat aactatatta aggtttggac aacgatccct
     4201 ttattagatt acatcaaaaa tacagtgatt tttgctggag ggacagtgat cacttctgta
     4261 ttctttgatt ctcttgcggg gtatgcattt gctcgtatgc gtttcaaagg aaaatcagtt
     4321 ttgttctatt tcgttttgct gacaatgatg atcccattcc aagtcttcat gattcctcta
     4381 tttattgaag tcaatttgct tggcatgctt gatacttatg caggtttgat cattcctcgt
     4441 atgacaactg catttggtat cttcatgatg cgttcctttt ttattacttt accagattct
     4501 ttggaagagg cagcacgcat tgatggatta agtgagttta atattttttt gaaaatcatg
     4561 ttgccattga gcaaacctac tcttttatca ttagggattt tcacgctgat gaatagttgg
     4621 aatgacttgc tttatccatt gatattgaca agtagttcaa aaatgagaac tttaccagca
     4681 gggttagctt tatttacagg gcagaacatt tctttttatg gacctgtaat ggctggaacg
     4741 gttatttcaa tgctgccatt actagtggtt tatatttttg cacagaaata ttttgttcaa
     4801 ggaacagcta tgtctggaat gaaagagtga ggaagatgaa aatagttgag actaaacttt
     4861 atggacagtt gattgtggtt tctgattaca tcttattagg tattctctgg gtaatcgtgt
     4921 gtttgcctgt tattactatc gtgcctgcta catgtgctgt ttttttatgt aatggcgcaa
     4981 tggaaaggtg agggatcagg aaatatcatt tattttttct ttcaaggaat aaagcaacat
     5041 tttggtaaga acttgttcct tagtctgtta acgatcatta tttattttct tgttaatcaa
     5101 ttattagaag aacagacaat cgtactttca attagtggat atgtagtttt acttatttat
     5161 tccatgtttc ttttatcctg gatatatgtg atttctgaaa acaaagatat cacattttta
     5221 caaatttttg aacaaagtgc atggaaagta ttttttgatt ttttgagaaa tattctttgt
     5281 tgcgtattgt tattaggatt tgtactgctc atatttcttt tccctccttt tatttttatc
     5341 tttgctggtg gcgtatggaa acttgtatct attatcttga ctataggaaa tgaaaggtag
     5401 ggaaagctgt tggacgaaga agtgaaagta aaaatcagag aggattttac ggtaggagag
     5461 atcagttctc ggctgtttgg ctcatttgtt gagcatatgg gaagtgtcgt ctatacaggg
     5521 atttatgaac cgggccatga aacagctgat ggtgacgggt ttagacaaga tgtcctctct
     5581 tatgtaaagg aattagaatt aggtgtcatt cgctatcctg gaggaaactt tacatctggt
     5641 tatgattggg tggatactgt aggtaggaaa gaacaacgac caaaaaaaat tgatttagca
     5701 tggcgaggta tagaaccaaa ttcttttgga ctccacgaat tttttaaatg gatcagtcat
     5761 gtacaagcga aaccgatatt cacggtgaat ttaggaacaa aaggaattga tgaagcaaaa
     5821 aatttagtag aatattgtaa ttttccaaaa ggaaccttct ggagtgattt aagaataaaa
     5881 aatgggcaaa aaaagccttt tggcgttaaa ttatggtgtt tagggaatga gctagacggt
     5941 ccatggcaag tgggggctaa gagtgcttat gaatatggta ggttagcaaa tgaagcctca
     6001 aaagtcatga agttagtgga tgattcaatt gaaacaatct tagttggaag ctctacgcca
     6061 cgtttaccat cgtaccctga atgggatcgt atcgcattag aagaagctta tgagaatgta
     6121 gattatttag ctttgcataa ctatattgat aagtatgatg aagaagactt gactaaacct
     6181 cctaaaaatg agcgtgatga tacagcgaca taccttgcaa aagcttatcg attcgatcgt
     6241 caaattgaag aaatcgttgc tacttgtgat tatgtaaaag gatatttgag aagtgagaaa
     6301 acaatgtatc tagcgtttga tgaatggaat gtacatgccc aaccggaaaa aagacatagg
     6361 gattttgaag tcggtagtcc catcgattgg tgttacttta ctatggaaga tacattatta
     6421 tttggttcat tagggctggc tattttacga cacgcagatc gcgtaaagat tagttgtcaa
     6481 tcattgttag taaacacaat acctttaata ctgacagatg ctaaaggaca agcatggagg
     6541 aatccaactt attatgtgat gcaacactta tcgaaatatg ctaaaggtca agtattgaaa
     6601 caacaaatca tttgccctgt ttatgattgt gaaaagataa aaaatgttcc ttatgtggac
     6661 agtgtgatcg tagataacgg caatcagctg actattttct tgatcaatcg cacaaatgaa
     6721 caacaaaaga taacgattga acatgatttc aatttgctag atcaaggaga gcactacaca
     6781 ttaaccagta gcgatctgtt ggacaaaaat acacgtgaag aaccagaaaa aataaaacct
     6841 gaaataaact atttttcaat agaaaaacat gacgaattaa atgtagggat agaaaaatac
     6901 tcttggaatg taattagaat aaagaaaatg tgaggaaatt tgttatgatg aagacacttt
     6961 ataataatcc tatcgttcgg caacgggcag atccttgggt atataaacat acagatggtt
     7021 attattattt tacaggatcg gttccaggct accaagtgat tgaattaaga agggcaaagt
     7081 cactgaatga attagaacat gctgcaagcc tgattgtatg gcaggctcat gaagaaggac
     7141 cgatgagtga attgatctgg gcacctgaag tccattatat caatggaaaa tggtatattt
     7201 actttgctgc aagcaatcat aaaactatac gtgatgaatc tcatcatcac cgcatgttcg
     7261 tacttgaaaa tcagcatata gatccaatga atacagattg gatagaaaag ggacaaataa
     7321 aaacgaaaag ggaaactttc agtttagacg gaacaacttt ctcttctcaa ggaaagctat
     7381 attatgtgtg ggcccaacaa gatcctgaaa ttactgggaa ttctaatctt tatctatccg
     7441 aaatggataa tccttggacg ttaaagggga agcagatcct cctttctata cctgagtatg
     7501 aatgggaaaa acggggtttt tcagtaaatg aaggtccagc agtccttact cgcaatggga
     7561 aaatattcat tacgtattct ggtagtgcaa cagatgaaaa ctatgccatg ggcctgctgt
     7621 gggctgatga gcacaagaat cttttattaa aagaatcatg gcataaatta tcggagccag
     7681 tattcgtttc ttctgaaaaa aataagcaat ttggtcctgg tcacaactcg tttacggttt
     7741 cagaagacgg gtgctttgat attttgatct atcatgctcg accagagaag aaccaaaaag
     7801 gggatccgtt agacaatcct aatcggcacg cgaacgcgca atgctttacg tggaatgagc
     7861 aaggatttcc agaatttggt gaacctgttc cgtatgcctt atgagcacaa gaaaccttga
     7921 tttttgcttg aataaacctt gcagactcgt tatgatatat gtacgtacaa ataaaaaggg
     7981 gcaaggcaaa tggcaaaata tcaagatatt gcagaagaga taaaacaaaa gatccttcgt
     8041 gaggaatacg aagtaaatac aaccattccc tcagaattca agctgcaaga aatatatgac
     8101 gtcagcagac atacgattcg gcaagcaatc gctgtgttgg taaatgaggg ctatctgcgt
     8161 aaagaaaaag ggtcgggcac atatgtagat gacagctata agaaagaaaa aacaccattg
     8221 aacagaacaa aaacgatcgg tgtcatcacc acatatctct ctgattatat ttttccgtcg
     8281 attatccgag gaatcgaaaa tgaattacga gaatctgggt attcattgct tttagccagt
     8341 acgaataacg atcacgaatt ggagaaagag tgtttgaaga aaatgattgc ttatggggta
     8401 gatggtttga tcgttgagcc tacgaaaagt aatcagtata acccaaactt agcactttat
     8461 gttgctttga gagaacaagg cattccgatg gtgatgatca atgctgctta tgaagagtta
     8521 aatgcctctt atatttgttt agatgatgtg aaagtcggtt ttatggcagc agaatatttg
     8581 ataaaaaaag gacatcagcg tctgttgttc atcacaaaaa tcgacgatct tcaaggaaaa
     8641 tacaggatga aaggttttat cagcgcgtgt gaacagtata atgtgcgttt tttgacggaa
     8701 gatatcatta ctttcaccac ggaaacacga gaaacaatcg ctgaaaaaac agtacaacgg
     8761 ttgaaagaag aacaagcttt agatggcatc atttgctata acgatcaaat agctagttta
     8821 atgctagata agttgacaga aaatggctat catattccag atgacctatc gatcgtagga
     8881 acagacgatt cttctttaag ccatttaggg aataaaaaat tgacaacatt gacgcatcca
     8941 aaagaaaagt tgggacaaga tgccgcacgg tggatcgtca caacgattga aaaaggacag
     9001 gcacagccaa atattctcta tgaacctgta ctagttgaac gggaaacagt gaaagaaaac
     9061 gaaaaataag agacgggttt ttaccgcctc ttattgctcc tacggttact cgtcgcaatg
     9121 tttgtgagag cttttgtcat cgctcaaggc tgaacgtttc tttcaccacc tctccactaa
     9181 acggtgttct cctaccaact ggtcacaagt cacaatattc atcaaacatg agaagctgtt
     9241 ttttgaaatt gttccttgtg actggaaact aagcggttcc ttcttatttc ttgaagctga
     9301 ccacttctgt cacaacctct ttaagaatga tggatagaaa tacgtttagg ataagttttt
     9361 ttagatgcac tttgttcgat ttcctctaaa gatttcccac gagtttctgg tacgatctct
     9421 tgaataaata aaacccctaa aaagcagatg atcccaaaaa tgccgaaaac gatttcttga
     9481 gacatagaag cagtcatcac aggaaaaagc aagccaacta ggaaagaacc aatccaatta
     9541 aaagaagagg ctaggccaga tgctcgcccg cggacagcta gtgggaatat ttcgcctacg
     9601 attacccatg tcagtggagc ccatgtgcaa gaataaaatg cgacataaat acataaaaac
     9661 aagagaatca acaacgaatt tgtatgagca tccagtacag ttcctaaaac agctggtagg
     9721 atgaaagaaa gtcccatcac gctaccgcct attttcaata aagttcgccg attgaacttg
     9781 tctgcaataa ccaaaaagag caaagaacca gcaactaaaa tgattccttg gatgatcggc
     9841 cacatcaatg catcgctcgc tgcatgccca gtcgcttttt ctacgatcag cggaatatag
     9901 taaaaaatag cattagctcc ttgaaattgc tggaatactg ctacaccaat accggcaatg
     9961 actaaggaac gatatttttc taaaaacaaa gtatgccaag aagttccggt tgtcttttct
    10021 tgtttgacat tcagctggat ttgttcgaat tcctgttcag cttcttttgg tgtccgaata
    10081 tagttcaata ctctttttgc ctcttccaag cggccagatt gcataagaaa acgcggtgac
    10141 tctggtagag ctaaaacacc gaaaaataaa atcagcgcgg ggacagcagc gagccctaac
    10201 atcacgcgcc aagccatcgt ttcaggcaac ccttttagca aataatctgc aacataggaa
    10261 aggagcatgc cagaagcaat catcacttga ttgatccctg acaatcttcc ccttagtcta
    10321 gcaggagcca tttcagacat ataagcagga actagggcag atgcagcgcc aacagctaaa
    10381 cctagaagaa tccttgctgc aatcagaaaa taagaaccat tgtgaggggc agatgcagaa
    10441 aggacagaac cagccataaa aataagtgca gaaagaagaa tcatttttcg tcgtccaagc
    10501 ttatcagaaa gaagaccaga taaagagccg ccaaggatcg cacctaacat gaccgaagac
    10561 gtgatccatc ctatcaaaga agctttacct gccaaacccc aatcatgctg taaaaaaggt
    10621 aaggcgccgg tcataacacc aatatcatat ccaaatagaa tgccgccaaa tgcgccaaaa
    10681 aaataaataa acgatgagga aacttttttt cttttttcat aagtattctc tccttctaga
    10741 atttcgagaa ggcggttgat cagattttgt aagcaatttc attttataac ttatgtacgt
    10801 acaaaacaag tgttttttat tgtattcttg taaataactg cttgacatgt acgtacaaaa
    10861 gtatacaata atcattgtaa gcgctactaa aaagacggtt tgatcaggtt tgacgagaag
    10921 gagggagtta aatcattatg aaggaagtaa atgcgcaaag tatgttagat gtcatagatg
    10981 gtcgtacatc tttagggatt gagtttggat caactaggat caaagctgta ttgattgatt
    11041 catcttttac tcctattgcc gctggtagtt atgagtggga aaacaaacta gaaaatggta
    11101 tctggaccta ttcattagaa gatatttgga aaggactgcg cgtcagttac cgaaaaatgg
    11161 cagcagaagt attcgaaatc tatggcgaga atcttacgac aatcgggtcg attgggttca
    11221 gtgcaatgat gcacggttat ctagcatttg atagcaagga acagttacta gtaccatttc
    11281 gtacttggcg aaatacaatc actgaagaag cagaacgaat attaacggaa aaatttcaat
    11341 acaatattcc gcagagatgg agtatcgctc atttgtatca atctattttg aataaagaag
    11401 aacatgtgaa agaaattaat tttttgacaa cgcttgcagg ttatgtccat tggcagctta
    11461 ctggtgagaa agtactaggc gtaggagatg catcaggcat gtttcctatc gatccttcaa
    11521 cgaaaaccta ccatcaagaa atgaaaaata tttttggtca gttaatcgaa aaagcgcacg
    11581 tagcgattga cttggatcac attttgccta aagttctagt agcaggagaa gaagctggca
    11641 agttaagcga atcaggggct tatctgatcg accctacggg aaatttgaga ccaggaatcc
    11701 cggtttgtcc gccagaaggg gatgcaggaa ccggtatggt cgctacgaac agtgtagcca
    11761 aagggacagg gaacatttcg gctggtactt ccgccttcgc tatgatcgta ttagaaaaag
    11821 aactagaaaa tgtccatccg gaaatcgaca tggtcactac accttcagga gaactagtag
    11881 gcatggttca tacgaataac tgctcttcgg atatcaatgc ttgggtcagt atttttgaag
    11941 aatttaccaa ttctttgggt atggagataa gcagagataa attattcacg gtattattca
    12001 acaaagcgct agaaggcgat acggattgcg ggggattact ttcttatggt tatttttccg
    12061 gtgaaaacat tacaggagta aatgaaggaa ggccattatt tgtacgtaca ccaggtagcc
    12121 gttttgattt agcgaatttc atgcggatcc atttagccag tgcttttggt gcaatgagaa
    12181 tcggaatgga tatattgaaa tctgagaatg tccaaattga tcgtttagtg gggcatgggg
    12241 ggatttttaa aacaccagaa gttggacagc ggattctagc atctgctatg gaggcaccag
    12301 ttacagtgat ggacacagcc ggagaaggtg gagcgtgggg aatcgcgtta ttagcagcct
    12361 atatgatgga tcgacatggg aagtctttag aaaacttctt ggcagaagac gtgtttggac
    12421 aagaccaagg aatcaccatc acaccttcag cagaagaaat agcaggctat cagatattta
    12481 tgagacgtta ccgtgagggg atcgacattg aaaaaacagc gattcatcaa ttgcaagaaa
    12541 aaggagtgat agaaaatgct ggaacaactg aaagaagaag tataccaagc aaatcttgac
    12601 ttgcctaaac acggactcgt caaatataca tggggaaatg tgagcgcttt tgatcctgaa
    12661 acacgatatt tcgttatcaa acctagcgga gtcagttatg aagagatgac agcagacgac
    12721 atggtcgttg tggacttgga caatcatatc attgaaggta aactcaatcc ctcttcggat
    12781 acgcctactc atgctgtttt atatcgttca tttcctcaaa tcggaggaat cgtccatact
    12841 cactcgacat gggcgacgat ctgggcacaa gcaggattgg atgttcctgc gatggggacg
    12901 acgcatgcag atacttttta tggatcggta ccttgtgctc gatttttgac acaacaggaa
    12961 atcgacagcg ggtacgaata tgaaacagga aaagttatca tagaaacatt caaagaacgc
    13021 aaaattgatc ccttagcaat tccaggggta cttttacacg gacacggtcc atttacttgg
    13081 gggaaagatg cgcaaagtgc ggtaatgaac gcagtcgtac tagatgaagt atgcaagatg
    13141 aatttattta ccagacagct caattcattt tcagaagagc tgcctcaacg gattttagat
    13201 aaacattatt tacgaaaaca cggaaaaaat gcgtattacg gacaaaacaa ataaaaggag
    13261 tggctaatta tgttgaatat tggagaaaaa gaattttggt ttgttgtagg atcacagcat
    13321 ttatatgggg aagaagcact gcgagaagta aagaaacatg cacaagaaat ggtcgatgaa
    13381 ctgaatgaaa atggccaatt gccttatcca atccgccttc aagaattagc agttactgct
    13441 gatacgatca caaaaatcat gaaagaggtc aattatcgag aagaagtagc aggtgtgatc
    13501 acttggatgc atactttctc accagcaaaa atgtggatcc gcgggacaaa gcttctacaa
    13561 aaaccattgc ttcatttagc tacgcaatat aacgaaagca ttccttggaa aacgatcgat
    13621 atggatttca tgaatttaaa tcaatccgct catggtgacc gcgaatatgg gttcatcaat
    13681 gctcgattaa ataaacaaaa taaaatcgtc gttggctact ggaaacgacc tgagatccaa
    13741 aaagagattg ctgattggat ggatgttgca gtagcctata atgaaagttt tggaataaaa
    13801 gtggctcgtt ttggtgacaa catgagaaac gtgggtgtca cagaaggaga caaagtggaa
    13861 gcacagattc aatttggttg gactgttgat tattttggta tcggagatct tgtacaagta
    13921 atcgatcgcg tatcagacga agaagtcgat caattatttg aagagtacaa ggaattgtat
    13981 accttcgact atggtgatta tgaagaaaag acatgggagg aacatgtaaa agtacaagct
    14041 cagcaggaaa tcggtattcg ccgtttctta gaagaaggag gctataacgc ttttacgact
    14101 aattttgaag acctgtatgg aatgaaacaa ctacctggac tagctgtaca acgtttgatg
    14161 gcagaaggat acggttttgc tggggaaggc gactggaaaa ctgcagcgat tgatcggttg
    14221 ctgaaaatca tggctcgagg gaaagataca ggattcatgg aagattatac ttacgagcta
    14281 gctagtggcc aagaagcaat cttggaatcc catatgatgg aagtagatcc gacgcttgct
    14341 gcgacgaaac caagaatcgt tgtttctcct ttatcaatgg gagatagaga agatccggcg
    14401 cgtcttgtat ttgatgggaa agcaggagaa ggggtagtcg tatcgatggc agatttcggt
    14461 acgcattata aactgctgat caatgaagta gaagcctttg aaccaacgac tgaagcacct
    14521 aatttacctg ttgcacgtgt gttatggaaa actaaaccga atttccatga aggtgtccat
    14581 tcatggattc aggcaggtgg cggtcatcat accgttgtct cgctaaatct aacaacagat
    14641 caaattgaaa cgtgggcaaa attagttgag ttggaaacag tggttattag ataaaaagag
    14701 gttgtgaaaa agccacttag ttttaagaaa taagaagaga ttgacgaaat ttgcttttca
    14761 acttttttga aatttagtct tattatcaat gtcagctaac ggaacaccat ttatcaagat
    14821 atctcaccct caatattttg ctctcgaaaa taaggcttat ggcagtaact tgtcatagcc
    14881 ttatttttat cactcagcct actctgctct aactgctctt tttgcttcta ggaagtcaaa
    14941 tggtaaacag ttgtctaatt gcagaaattt cgagatactt gttagtaagg agggggtttt
    15001 atgtatcacg ttcatttgat tgatgctatt ccagaacaag agatagaaaa gttacaaggg
    15061 gaatatttca aaataataga tgatttgcca gccgaaggaa tagttattcg tagtacgaaa
    15121 gtgaaagatg aatggcttac accagatttg ctagcaattt caagagctgg tgttggggtg
    15181 aacacgatca acgttgaaaa agcttctgaa aacgggacga tcgtcatgaa tacaccaggt
    15241 gtaaatgcta atgcagtaaa agagcttgtt ttgtgctgtt tgctcttatc ttcccgtccg
    15301 ataatcgaag caagtcgtat ggtacaaaca ctaacaggtc ctaatatttt agaacaggca
    15361 gaaaacaaaa gaagtgctta tgtgggacga gaattgcaag gcaaaaccat cggtcttctt
    15421 ggtcttggag cgataggcac aaaagtagcg ctaagttgct atagcttagg gatggatgtc
    15481 ttgggttatt ctatccgcga tgcccagttg gattatgttc ggcaagcaga tttagaaaca
    15541 gttctttcta cctcggatta catcgtagtc atgctgccgt tgacagaaga tacaaaagga
    15601 ttgatcgatc aggcgaatat agaaaaaatg aaaaaagatg ctgtacttat caatgtagga
    15661 agaagtgaaa ttgttgataa atatgctgtt atgcaagcat tggaaaaaca acatctggct
    15721 aaatacttga ctgattttcc agaagaagag ttcttagaaa atgaccgtat acttatgttg
    15781 cctcatctag ggggatcgac tcaggaagct ttggcagaca gcggacgttt ggcagttgaa
    15841 gccttaaaag attatctttt gttcggtacg gttagagaag cggtcaatta tccatccgca
    15901 cgaatgtttt tccaagcgcc gtttcgattc actatatttt atcaaaagaa aaccaatata
    15961 ttagcagaga tattttctct gctgaatgag aacgagctag cgatcgcaga tatatcgcgt
    16021 aaccataaga atgagcatgt ctacatattg attgacatag acagtactga ttttgaacag
    16081 ctcaatcaag tgaaacaaca gctagaaaaa atttctggag tacgaaaggt ccgcttatta
    16141 aagaaaccag aaaggccata aagaaagaga atatttggat ttcattaatt cttctttccg
    16201 ttctttactt tcgaatttcg tacaactaaa ataagagaag caacattctt ttattgatag
    16261 aaatgaagga gcaagcattt gaaaagatat ataagcagac tttcgaccaa acagaaaaag
    16321 attttaaaag gaacagcagc aatcatcagt atcttttttc ttgttgtttt tagtaattta
    16381 tttttgcagt ggtgtcaaaa tgatctatcc gtagaccttg cgttgaaatt tgctttttct
    16441 tggcatacgg aaaaattctt cttagcctgt ctcgtcttgc tgattattct tatttttctg
    16501 attgcactag caggatctgt ccctttaggt tcccttacgt atgtcgtagc catcggtgta
    16561 ttaggttttg caaattatat gaaaatgagt tatcggcaag aaccgattta tccagacgat
    16621 ttgaagatga tcactgaaat cggattgctg aaagatatga ccggcactat gctgtttaca
    16681 gtgatcttag ctgccgcagg aaccgtgata ggattgtttt gctggtacat gtttcgaagc
    16741 ctgaaaaaag gaaggcgatt ccaattgatc cgattaacga cactgcttgt ggcaattgga
    16801 ctgctagggt atatcagtaa tttcaacaat cccgataatt tgttgcgaaa agcatataat
    16861 aaaacggcac tatggatacc ttacagccag aaaatgaact actataacac tggttttatc
    16921 ggtgggtttt tgtacaatct gaaggtagaa ccaatggatg aacctgaagg atattcgaaa
    16981 gaaaagatca aagaaatcac tgaaaaatac cagaagctag ccgatgaaaa aaataaaact
    17041 gtagaggaag agtcgccgaa catcgtgttc gtgatgagtg aaagtttctc agatcctagt
    17101 cgattaaacg gcgtagaagt atctggtgag ccattggcag attattatga agtagctgat
    17161 caaacatata gtggcaatat gctttctcaa aactatggcg gtggaacagc aaatatcgaa
    17221 tttgaagcat tgactggttt ttctatggcg ttatttaatg cgcaactcac caccccttac
    17281 acgatgcttg taccaaaaat ggatcagctt ccttctatcg tttcagcgtt aaacgcacaa
    17341 tcataccaga cgacagcgat ccatccatac aatacttcga tgtataaaag agaggatgtt
    17401 tatcagacat taggatttga ccagttcatc agcgagcgta cgatgaccta tacggatacg
    17461 atagagaata atccatatat ttctgatgag tcagcttaca aagaagtaat gacacttctc
    17521 aaggaagaaa aaacacctca gttcattcat ttagtcacga tgcagacaca tatgccctac
    17581 gatggaaagt atgataatct agactatcct gcaaaaactt cagatggaag tgggacactt
    17641 gacttagaga attatctgca agatatttcc tatagcagca cggcactgaa gcagttcacg
    17701 gaagaattga agaatctttc tagaaggact ttagttgttt tttgggggga tcatcttcca
    17761 gggatctatt cagatacgat ccaagcaaaa aatgacaaac aaacattgca tgaaacacaa
    17821 tttcttatgt tcgacagtaa aggagaatta gaaaagcaaa cgactcacga tgcaatcacc
    17881 agtccgtttt attttgcagc gaatctaatg gaacagacga atcagacaac aaatggcttt
    17941 tatcagctgc ttttatcatt agaacaggaa cttccggcgt ttgaacgaga actgtactat
    18001 caaaacggac agtggtataa agaagcgcaa ttcaatcgct cgcaacaaga gatttacgac
    18061 gaatatcaat tgatccaata tgacattgtc gcagggaaac aatatagttt agcagatggt
    18121 ttctttgagc acgaataaga atggcgagct gtatagaaac cattaaattt tttcaagtac
    18181 ttgtcatttg aggataaaaa caagtagaat aaataataac aacaatggag aaagtaggaa
    18241 aacgaacatg ttaccgaata ttggctatta tgtgcagtcc atcgatcaaa tcgtcaagga
    18301 aacagaagca atcggagaag gaatgcatcc gaaatatgaa gtgatcagaa acgcaattga
    18361 tgaaggaaaa acaagtgaac tggacaaatc gactcttgaa gagatcatcc tgttatttga
    18421 agaaggaaca aaaaaatatc gggcaatgct tatgaaagtc agtactttgc gtccaccagc
    18481 aaaagcaatg ggcattcata aaaattttga aaaagcttat ctttcatatg tagcaggctg
    18541 tgaagaaatg atccaaagta tcgatcttga atcaggggta gatgaagatc tattcaatac
    18601 atctgaagca aaacaagacc aagcgacaga ccaattgaca gctgccatcc aaaaaatgac
    18661 taatttgttg ttgaaaaaat aaaagaaatc tttgataaca ataaaaacta gagttatcta
    18721 atataaatgt aatattacct ttatgataga gtgatcaaaa tcctttatga taatgacata
    18781 cctataacca acaacaacct tgtacttact caaaatcgag taaatactcc ttttccgtcg
    18841 agtctaacca tctcggcggt tttttatttg tagaaaagaa catcaggata gacggaaaag
    18901 tcttgtcctg atgttctttt cagatagtat ggaaagctga ttagttttct acattctgta
    18961 catattgttc aaagtagttc tgtaaatcgg ctttgagttt ctgatattcc tcttcgctat
    19021 actctttatc ttcgattttc ccatcaaaga aaggaatatt tagttcttcc cgtagtctgt
    19081 ctaatacgtc ttgctgattc atttcattct ccttttctta ctaacgatca aaataaacac
    19141 agacacattc tggtacatag acatcttttt tcagtaattc cagtaatcct gtttcaggat
    19201 gacggcgata taatgtcaga ttatcggtgt tctgattggc acacacgaca aaattattgc
    19261 ttggatctag tgcgaaatcg cggggaaaat ccccttctgt tgagatgatt tgcttgtttt
    19321 gaatgtggga accatcttca aaaactgcga atacagcaat cgagttatgt cctcggttag
    19381 aagcataaag gaacttgcca tcatttgaaa tgcggatagc tgcccctcca ttttcaccgt
    19441 cgaattcttc tggcaaggtc gatattttct gtaattcttc aaaagcacct gtttctttat
    19501 tataagaaag cacgcggact gtgctgtcta attcaccaaa taaataagcg aattgtccat
    19561 ttggatgaaa gacaagatgg cgagggcctg ttcctggctc tgcagtgaag gtagttacaa
    19621 gattcaattt gccgttttcg gacacatcat aagtatacac acgatctgta ccaagatcac
    19681 atacgactaa tcgttggtca ggagtcagat ccgtatagtg gacatgcgca tgatcttggt
    19741 ttttatgagg acctgtcgct tcttgatgga atattgaatc tgctgctttc agttcgccat
    19801 ctcctaatat atggtagaca tttacttcac ctttatgata gttcgccccg tatagtaatt
    19861 gacgtgcttc atcaaccgct acataacaca aaggagcgcc agactctgtt accgcattca
    19921 aaaaatgaaa atccttatcg tacgcaccgg caccacctaa tccatccaca ctagtaactg
    19981 tgtaaagatt gccagcttta ctttttgcta cataggtagg gctattttct tcaacagcta
    20041 atgaaaggtt ggctaattct tctttttctg tatcaaggtc gatcgtatag attcctttac
    20101 tttcgcgacg cgtataggtt cctaaaatta tcttttcgat catatgagct gattcctcct
    20161 aattgtaatg aaatagtttt cgtttttatt ctatcacata attattccac acggctaaag
    20221 aatgagaatg tgttatactg tttttgaaag caattaaagg agagagtgca atgattcagg
    20281 caaagattac agaaattggg acagaagcaa taaacaagga agaacccatg ctgattttgt
    20341 tcgataaaac agcaacagct gccttacgaa aatattcggt gattcaagaa gtatcaaaag
    20401 acgaaccttt ttctttgaaa gcaggcggaa caattgcttt tgatgatcag gtatatacga
    20461 tcgattatgt cggtccgatg gccaatggga atttaaagac agtagctcac gtatcattga
    20521 tttttgatgc ttgtccagaa gaaggacaaa ttgcaaatgg aatctatctt catccgcata
    20581 gactgcctgc tattggtttg ggaagccaaa ttttttataa ctaacaggag gaattatgga
    20641 aggaaaaaat aagaagaaca gaccggtatc gtggttttgg cgctggtttt taaataatca
    20701 agtagtcaca gccttacttg ttgtattgtt aatattgctg atcgtctttt tatttacaaa
    20761 agtttcatat ttgtttgcac caatctggca atttttagca atcgtaggtc tgcctatcat
    20821 tttagcagga atcttgtatt acttgatgaa tccggtagtt gattactttg aaaagcgaaa
    20881 agtaccaagg ctttacagta tcattgggct gtttgttttg gttgttgcac taatcgcatg
    20941 ggggagcgta gtgatcatcc ctaagattca ggaacaaaca gtgagcttca tcagtaactt
    21001 ccctcaatat gtagatacga ttgataataa attaaccgag attttgcggg acccgctgtt
    21061 caaccaattt cgcgaacagt tggaaacagc aggtgataag ttcatgaatt cggcaggcga
    21121 tatgatccaa gatatatcta agagtacagt tcagagtctt ggaagttttg tcggcgcggt
    21181 agcgactatt ttagtggctc tgctgacgat gccgtttatc ttattttatc tattgaaaga
    21241 cggtaaacaa ttagcacctt attttgtcaa atttttaccg acacgcatgc aaaaaccgac
    21301 gttgaatgtg ctgagtgaaa tgaatagtca agtttcttct tatataagag gacaactaac
    21361 tgtggctttt gctgtggcaa tcatgtttat gattggtttt gcggtcattg gtttagagta
    21421 tgctgtcacg ttggggatta ttgcgggttt tttaaacctg atcccttact taggatcatt
    21481 tttagcgatg attccggcta tctttttagc cattgtagca ggtccattca tgatcatcaa
    21541 agtactgatc gtttttgcag tagagcagac aatagaagga cgcttgatct ctccattagt
    21601 actagggaat cagttagcaa tccatccagt aacgatttta ttagttctgc tgacttctgg
    21661 gaaattgttc ggaatcatcg gtgtgatctt ggggattcct gtttatgcag cagctaaagt
    21721 agtgattact catgtttttg aatggtacac aacaatctct tctctttatg aagaaaatcc
    21781 gttgaaaaag cagaaagaat aacaaaaaga gacagatggg aaaatatcca aggcacaaat
    21841 gctgctttga agatt
//
LOCUS       DACCVH010000045        21813 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.045, whole genome shotgun sequence.
ACCESSION   DACCVH010000045 DACCVH010000000
VERSION     DACCVH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.045"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="IVV98_001715"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="IVV98_001715"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP7807371.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="IVV98_001716"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="IVV98_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP7807372.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="IVV98_001717"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="IVV98_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP7807373.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="hflB"
                     /locus_tag="IVV98_001718"
     CDS             complement(4246..6357)
                     /gene="hflB"
                     /locus_tag="IVV98_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP7807374.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="IVV98_001719"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="IVV98_001719"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP7807375.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="IVV98_001720"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="IVV98_001720"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP7807376.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="IVV98_001721"
     CDS             complement(8557..9027)
                     /locus_tag="IVV98_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP7807377.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="IVV98_001722"
     CDS             complement(9073..9498)
                     /locus_tag="IVV98_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP7807378.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="IVV98_001723"
     CDS             complement(9565..9834)
                     /locus_tag="IVV98_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP7807379.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="IVV98_001724"
     CDS             complement(9845..11440)
                     /locus_tag="IVV98_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7807380.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="IVV98_001725"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="IVV98_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP7807381.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="IVV98_001726"
     CDS             complement(14993..15553)
                     /locus_tag="IVV98_001726"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP7807382.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="IVV98_001727"
     CDS             15906..16880
                     /locus_tag="IVV98_001727"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP7807383.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="IVV98_001728"
     CDS             17050..18450
                     /locus_tag="IVV98_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP7807384.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="IVV98_001729"
     CDS             complement(18528..19250)
                     /locus_tag="IVV98_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7807385.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="IVV98_001730"
     CDS             complement(19329..19835)
                     /locus_tag="IVV98_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP7807386.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="IVV98_001731"
     CDS             19958..21757
                     /locus_tag="IVV98_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP7807387.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6053 a         4752 c         3911 g         7097 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ttgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttg
//
LOCUS       DACCVH010000046        21102 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.046, whole genome shotgun sequence.
ACCESSION   DACCVH010000046 DACCVH010000000
VERSION     DACCVH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.046"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            175..519
                     /locus_tag="IVV98_001732"
     CDS             175..519
                     /locus_tag="IVV98_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP7807388.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="IVV98_001733"
     CDS             520..939
                     /locus_tag="IVV98_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP7807389.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="IVV98_001734"
     CDS             complement(1031..1381)
                     /locus_tag="IVV98_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807390.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="IVV98_001735"
     CDS             complement(1347..2678)
                     /locus_tag="IVV98_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAP7807391.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="IVV98_001736"
     CDS             2934..3500
                     /locus_tag="IVV98_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7807392.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="IVV98_001737"
     tRNA            3645..3732
                     /locus_tag="IVV98_001737"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            complement(3784..4989)
                     /locus_tag="IVV98_001738"
     CDS             complement(3784..4989)
                     /locus_tag="IVV98_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7807393.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5127..6015)
                     /locus_tag="IVV98_001739"
                     /pseudo
     CDS             complement(5127..6015)
                     /locus_tag="IVV98_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6102..6302)
                     /locus_tag="IVV98_001740"
     CDS             complement(6102..6302)
                     /locus_tag="IVV98_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807394.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6331..6753)
                     /locus_tag="IVV98_001741"
     CDS             complement(6331..6753)
                     /locus_tag="IVV98_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7807395.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6770..7192)
                     /locus_tag="IVV98_001742"
     CDS             complement(6770..7192)
                     /locus_tag="IVV98_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807396.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7483..7674
                     /locus_tag="IVV98_001743"
     CDS             7483..7674
                     /locus_tag="IVV98_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807397.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7685..7951
                     /locus_tag="IVV98_001744"
     CDS             7685..7951
                     /locus_tag="IVV98_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807398.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(8192..8671)
                     /locus_tag="IVV98_001745"
     CDS             complement(8192..8671)
                     /locus_tag="IVV98_001745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807399.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8716..9423
                     /locus_tag="IVV98_001746"
     CDS             8716..9423
                     /locus_tag="IVV98_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP7807400.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9602..9943
                     /locus_tag="IVV98_001747"
     CDS             9602..9943
                     /locus_tag="IVV98_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807401.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9936..10682
                     /locus_tag="IVV98_001748"
     CDS             9936..10682
                     /locus_tag="IVV98_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP7807402.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10688..11374
                     /locus_tag="IVV98_001749"
     CDS             10688..11374
                     /locus_tag="IVV98_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807403.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11381..12214
                     /locus_tag="IVV98_001750"
     CDS             11381..12214
                     /locus_tag="IVV98_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAP7807404.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12231..13082
                     /locus_tag="IVV98_001751"
     CDS             12231..13082
                     /locus_tag="IVV98_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7807405.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13079..13438
                     /locus_tag="IVV98_001752"
     CDS             13079..13438
                     /locus_tag="IVV98_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAP7807406.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13453..13614
                     /locus_tag="IVV98_001753"
     CDS             13453..13614
                     /locus_tag="IVV98_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP7807407.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13611..13916
                     /locus_tag="IVV98_001754"
     CDS             13611..13916
                     /locus_tag="IVV98_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807408.1"
                     /translation="MSVGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13916..14230
                     /locus_tag="IVV98_001755"
     CDS             13916..14230
                     /locus_tag="IVV98_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP7807409.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14407..14718
                     /locus_tag="IVV98_001756"
     CDS             14407..14718
                     /locus_tag="IVV98_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807410.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14715..14933
                     /locus_tag="IVV98_001757"
     CDS             14715..14933
                     /locus_tag="IVV98_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HAP7807411.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14946..15227
                     /locus_tag="IVV98_001758"
     CDS             14946..15227
                     /locus_tag="IVV98_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807412.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15224..15550
                     /locus_tag="IVV98_001759"
     CDS             15224..15550
                     /locus_tag="IVV98_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807413.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15547..15744
                     /locus_tag="IVV98_001760"
     CDS             15547..15744
                     /locus_tag="IVV98_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807414.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15741..15950
                     /locus_tag="IVV98_001761"
     CDS             15741..15950
                     /locus_tag="IVV98_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807415.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15947..16234
                     /locus_tag="IVV98_001762"
     CDS             15947..16234
                     /locus_tag="IVV98_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807416.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            16826..17293
                     /locus_tag="IVV98_001763"
     CDS             16826..17293
                     /locus_tag="IVV98_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP7807417.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            17592..17933
                     /locus_tag="IVV98_001764"
     CDS             17592..17933
                     /locus_tag="IVV98_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807418.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(17926..18105)
                     /locus_tag="IVV98_001765"
     CDS             complement(17926..18105)
                     /locus_tag="IVV98_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HAP7807419.1"
                     /translation="MYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQTINSI
                     KNGITKDSQVIDVTK"
     gene            18467..18679
                     /locus_tag="IVV98_001766"
     CDS             18467..18679
                     /locus_tag="IVV98_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807420.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            18686..18910
                     /locus_tag="IVV98_001767"
     CDS             18686..18910
                     /locus_tag="IVV98_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807421.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            18937..19470
                     /locus_tag="IVV98_001768"
     CDS             18937..19470
                     /locus_tag="IVV98_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HAP7807422.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            19457..20701
                     /locus_tag="IVV98_001769"
     CDS             19457..20701
                     /locus_tag="IVV98_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAP7807423.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            20714..>21102
                     /locus_tag="IVV98_001770"
     CDS             20714..>21102
                     /locus_tag="IVV98_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7807424.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIE"
BASE COUNT         7477 a         3336 c         4166 g         6123 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatatc aacgattaga cacgatttcg atcgtgtctt ttttgttgta
     3781 tatttagcct aaaatgtttt ttgactcccc ttttgactcc ccctgagtac tgttcttcat
     3841 aaatgctaca aaattattga tgactttttt gttttgagtt tcagttacat gagtgtaaat
     3901 atttgaagta gtttgaatgt ctgcatgccc taaacgttcc tgaacatctt ttaaagaagc
     3961 tcctgattca aaaaggagag aggcatgagt atgtcgaaaa ccatgagtag tgattctttt
     4021 agtcaattct ggatgatgct tatatatgac attaagccac gaacgtgaaa ctgtagggtt
     4081 atagagaaga ccatcatggt gaaaaattaa gttttccctt tggattgtaa cgatcgtttt
     4141 gttttttgta taatactttc tcaataaact gatcaaatca ttgtccagat aaatttttct
     4201 ttttccagat tttgatttag gagtatttac gatcaatctt ccttgataac ctcttgttac
     4261 agttttattg atattgagtg ttttgctctt aaagtcaata tccgaccagg tcagagcaaa
     4321 agcttctcct tttcttatac ctgtaaaagc caatagggaa aagaataaat atctttcatc
     4381 atcatcgttt cttattgctt ctaaaaattt gattaattct tctttagtat aaaattcgat
     4441 atttttatct tcgatatcta gagcttctcc acgtggaata gaaactaatt tcataggatt
     4501 gctagttata atttgtaaag aagcagcgta atcaaaaaca ttagatgtgt aattttttat
     4561 tttcttaaaa attttaggat ggctatcgga ccaagtgttt actgcttctt gacagaaaaa
     4621 aacgtctatt ttgtcaatga acttatctcc aaacactttt aagatgtgtg tgtcaaaaat
     4681 ttgtttggtg gaggaccaag tgctttcttt aactgtcttt ttataatttt caaaccataa
     4741 gccgtaaaca tattcgaatt tcttgctctt ttgagctgta gaagcttgca gtcctttttc
     4801 ctgtatatct gcctccaatc tttttaaagc tctctcagcg gctaatggcg tactaaaacc
     4861 tcgtctcgtt gtttttcttt tttttcctgt tagaggatca actcctaagt acagactaaa
     4921 ctgatatttt tcttcgcctt tttttgttaa gtgcttttta attcgtttat caatttcttt
     4981 ttttgccatc tttatctttc ctttcgtacg tttgttcggt tgtacagcgg atttcgagat
     5041 ggtaaaatag ggtacaacaa atagacctac tttaccgtag ctctttgcac atttgcgttc
     5101 ttggtcgggc ggcaaatgtg ctttttttat ttcactctta gttcttgtcc tggataaagc
     5161 atgtagttgt ttggatccat accgtttaat gcaaacagtt gatctaccgt aattccagct
     5221 cgttcagcta tttgtttggt cccttcacca ggttgcaaag tcaaggtttc ggtttcagat
     5281 gaagaaggtg ccgttggttg agcttgatta gctggtacat aatcttgtgg tactgattgc
     5341 tccgttgaac tgggagtggg tgaaacttgt tcaacacttg aactaggagt agcttctgca
     5401 tagttttcta cactttcagc agagtaagta ctactagttt caggaggcgt attctgcgca
     5461 atagcagctt gttctacagt actagaagat gcaatagtac tttctgttgt agtcgaagat
     5521 gattgttcgt tgctacttgt tgagctagta gttgttctag attctttagt ttttttcctt
     5581 tttgtagggt ttcaaaacta atttctcatt atcatcagat ttgttaggct tttctggagt
     5641 taaaataata tttttatctt ctttgctgac agtatatttg gcatcattat ctttgtcttt
     5701 atcatctttc caagtcataa catcgccttc aagtgtatac tcaaatttgt aattcatttg
     5761 gtcgactaag cttttagcaa attcttctcc catagcctcc caatcgttac ttgaagttga
     5821 tttcatagaa cttgtgtcaa cactaaaaga tacgacgtga tcagaaaatg atacgatcat
     5881 attaggttcg tcatctttgg ttgcttcaat caaccaatca ttagctttta aatcttctgt
     5941 agttactttt ttaccacaag cagtgaaaag taacagagaa gcaaaaacta ataaacttgt
     6001 tattactttt ttcatttttt attcctcatt tctatgatat gatttttatt ggggaatctt
     6061 agaaataagg tttcgagtcc gtgttgctgc acgggctttt tttatttaaa taaatcccaa
     6121 aaactgaatg tagttttctt gtatacttta ttgtaagcag ccttttttgg gtctttaatc
     6181 cagccgctac cttttttccc ataaccagga ataactgctt tttttacttt tctttttgct
     6241 tttccagtgg ttctagcgct tatggatttt tttatacttg gttttctcat tcctattttc
     6301 atctatatcc tccttacgtt gtattataat tcacaagaaa cgatcgaatt catctggtaa
     6361 tccaaagcag acgagctttt catattttgt catatgatca aagccgtcta aagttggatc
     6421 aatagtcaga tgagttgcga aataatttgc ttctttttca atttttaatt cagatactag
     6481 cgttttttta gacaacatag gtgtgttttc attcggatgc aaaacacagt ggcctaattc
     6541 atgactacaa gttatccatt ttcccatctc atctaaacta gaatttatgt ggatcatttt
     6601 tatctgtttg aatttactat agtaaccata aatttctccc aaatcttctt ctaaaactag
     6661 tatcttcaat tctcgtgcaa ttctaaaagg attgcgtgtt tgatatagtt ttaccagctt
     6721 attaattttg ttatcaattt gaggtaaata cataaacaac gtactccttt taatcgcgat
     6781 attttttagg tgtgtatttt ttcttagctt ctattttagc tattcgcaaa gcattctcta
     6841 aagaaataat gagagcttca cgtgtcgctt cactcatttc attatctttc ttcgaaaaag
     6901 ccattccatc agcattagat aaatcgtcga ttaatgactg caattctttt tggatatcac
     6961 gctcgtcttt ttctgttaaa tcatagtatc tttttttctc agtacgtcct agcaaataat
     7021 ctacagatac gtcgaagtag tcagcaattt cttgtaactt ttcggcagtt ggctgttttc
     7081 ctgcgtttaa actataaaag taattctctc cgtacttcaa atctttagcg acttgttgaa
     7141 ggtttttatt cttgtttttc gctagttctt ttattctttc aaatgttgtc attccaacgt
     7201 tcctttccaa cacgaaaaaa taatttacga aaaagagtaa aaatagcttt acaattttac
     7261 gatatagagt tattatttat ccgtaagtta atttgataga aaaaagcaaa ctaaaaacac
     7321 accttatagc ataaagtttg gcgaccaagt gcaaataaaa ggttttgtta taggcttatt
     7381 tctctatgta ttcattttac tctatagtgt aaaaatgtca atggaaatta tattttttct
     7441 atcattttaa cttacaaatt tataaaaaaa ggaagtgggt taatgtcaaa cttggataac
     7501 ggtcgtgcgg cgatcaaaga gtttatgaaa gagaatggaa taactatgga tgatttggct
     7561 actgcttatg gtcacacgcg tgtacgaatg caacaaattc ttgatggaca ctggagtgga
     7621 ccaaaggcaa acagaactat tctagagatc atccgtgatt acagaattcg ataggaggca
     7681 agtcatgaat attctaagcg aagagttttt gactcgttta agaattgcaa ttgttgaagt
     7741 tgtaaaggac gcacttagtc aactttcaaa aaagaatttg tcagaaacac gatatttaaa
     7801 aaagatcgaa gctagaaaat atgtgggagg tgtaaacgat caaggttttg agaagttaat
     7861 agctcacggt ttaaaagaaa ttcgtataga tggcttttta agatatgaca aaaaggacat
     7921 cgatgaactg atggctaaat acaaaattta aaggaggtca acatgggaaa gtttaatcga
     7981 acattagtat tcagcgcgcc actaattatc tacgctttag gtctatgggg tagtagacaa
     8041 gcattaatcg gcacgatcgt ttacatgctt tggattttca ttgggcttga tgaagctgag
     8101 tacagagcga aaaagccagt cgggagggac tgactaaaaa agtctaatgt ctataagaaa
     8161 ggtttgacaa taaatgaaag aattattttt tttaataact ttcatcattt tttctatcag
     8221 tgttttctac attaaccttt gcgttgctag atttgctttg aaaagtttta ggaacagcaa
     8281 acgaaaatag agctataaaa gatacgaatg tagtagctac gttaaattgc tctttagaaa
     8341 acgtcaatgt cattggaatg ataattgata tcgatgagaa aatctttgcg ataataacta
     8401 tccatttttc aattataaac atttttaaat taagcaccat tagacaaaat gtagttccta
     8461 tatagaggat aaatgaagat agaaataaac atattagtcc agttttaaaa aaagagaagt
     8521 aatctatgtg ggcaaattct gttaatatgc ttttttgatt taacacaatc aaactactgt
     8581 tggacaaaaa tgacagtaag gaaagagttg ctccgattac taaataaaaa atagttgtta
     8641 acaatattat attatcaatt tttctgctca tgttttcacc ccaccagaat tatatcaaaa
     8701 aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc tgtgactacg
     8761 agcttacaag ttgcagaaag cttcgataaa aagcacagac atgttttgac ggctattgat
     8821 gaactaaaag agggggttgc cgaaaattgg gcagacctat tttgggaaga tacttatgtt
     8881 catcctcaaa ataaacaatc ataccgaatt atttatatga atagagacgg cttctctcta
     8941 ttagcaatgg gcttcactgg taagaaagct ttaagtttta aacttcaata tattgaggcc
     9001 ttcaacaaga tggaaaaaga attaaaagac caattgccat caattccagc aactaaacga
     9061 gaaatggcat tacttgctct agctgcaaac gaagaaacga atgaaagagt agacgctatc
     9121 gagtctgatt taaacgattt gaagaacaat caacttctag ctgaaccaga ttaccgaaca
     9181 atttctaata tggttcgcaa caaaattaga gttatttgta atcagcagca tttaaatagc
     9241 aaagcaaaag cagaattgtt taaagacttg aatggcggaa ttaagcgaat cactggagca
     9301 gtagctagaa atcgtatcaa ggcaaaacag ttcgatgatg ttatcgattt tattaacaat
     9361 tggatgcctt ctacagcgac gatgacaatt attaagcaaa tggagttgtt agaggatgaa
     9421 tagagctgaa gcgctaaaaa taggcgtaat aattgctaat cgctggtgga gacacaataa
     9481 accaaacatc ctaagccaac aacatattga taagcaaaaa gcatggcaac aaataaaaaa
     9541 gtgactcagc cgaccaaagc aatgagtcac aaagaaaata catctaagga gatgttacca
     9601 catgaaaaaa gaactttcca ctctagatca atatttgact gatcctagtt ggggcaaatc
     9661 gaatatcaag gaaacaagca atcgaaaaat cagacgtaat cttttgacgg atgaagaact
     9721 agcatgtgat caagacgatt tgggaaattt tgtgagtatt tgggatcatg tctatcttat
     9781 ccatttatcg aggaagtcca aaaaaactga atatatctat gtcatcgaag atggcttgat
     9841 tgatgcgcta gaagagtatg acagagataa cttgattgat atctcttatt acggatcagg
     9901 taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaaaggaa caacctttga
     9961 aaaatagaag tgataatacg ctttttaata ccttatacaa aataaatgtg aaagatgtta
    10021 ctgaaaaacg aaataacctc acttatcttt cgtgggcatg ggcttgggca gaagttagca
    10081 aagtgtgtga ggcagtagat tatgaaatct atcatgatcc agaaacatat ctgccgtatg
    10141 tctttgataa gaaaacaggc tatatggttt ttaccagtat cacagtcaac ggagtaaagc
    10201 gtgacatgtg gttaccagtc atggatggtg caaacaaggc aatgaaagat gagccatata
    10261 cctacgaagt caatgattat cagtggaata acgaaacgaa gaaaaaagag attgttggaa
    10321 aaatcgaaaa gcgagttgaa gcagcaacta tgtttgatat caacaaaacg atcatgcgct
    10381 gtcttgtaaa aaatctagca atgtttgggc tagggctata tatatttgct ggcgaagata
    10441 tgccagaaga tgtctcgatg cttgaaccag ctactcaaag aagcaaaaag ctattcttgg
    10501 atgctttaca actggttgct aacaagtacg aaaaatcaat tgatgaagca attgttgcat
    10561 tgactgatgc ggcttctata accgctgatg acagtaaatg gaccaagaga gacttgggca
    10621 ttctaaaacg aggcgttaac tggattgaag atcagtacag agaagaaaca aaagagaagt
    10681 gatatgagtg tttaaaccat tgatcgattc atattcagcg gttctgaaaa agttcaaagg
    10741 aaaagacata ggtgcaacga tcaatgaaga agtgaacatt gatcgactaa agacgatgta
    10801 tgacggatat gatggcgatc ggattattga agttcgattt attgatccac gtcgatttac
    10861 tgtgcagcaa cgaaacttca tctatgcgct gataggcgat attttcatcg atacaggcat
    10921 gccaacggac ttctggaagg aattctttta cttccgtttt gaaggcgtca cagggcgcaa
    10981 aataagcctc aaagacgaat cgaatacaac tgtgagtgat gctaatgtct tagcaaatat
    11041 catcttagat ttcatctttg aacatcatat tcctttcaaa gaaggctatg agattttacc
    11101 agcgaatcaa gaatattact tctacaaatg catcacaaaa agagtctgct gcatctgtgg
    11161 caaaacagga gctgacatcg atcactttga caaagcgcta ggaagacgaa agcgcaaaga
    11221 agttgatcat tcagagtaca catttgcagc actctgcagg attcatcaca cggagaaaca
    11281 caatataggt gtgatcaatt tcaaaaataa atatcaaatc aaagggatca agttaaacca
    11341 ggaaacaatt aagaaactta gaataggagg gtaaaaaata ttgtctgaca acaaacgcta
    11401 ctactattta aaactaaaag agaatttttt cgatagtgac gagatggttc tcttagaaag
    11461 tatgccagat ggctatattt attctaatat tcttctcaaa ctttatttaa gaagtctaaa
    11521 acacgaaggt aagttgatgt ttaatgacag gattccattt aactctacaa tgctcgcaac
    11581 tattacaaga cattctgtag gagtcgtaga aaaagcggta caaattttcc gtgatttgca
    11641 gcttattgac gtattagata acggagcaat ttatatgtct gatatacaaa gtttcattgg
    11701 aaaatcctca actgaagcag atagaaaaag agaatacaga aagaaaatag aagaggcaaa
    11761 acggaattta ataactggag gacaagtgtc ggacaaatgt ccagacaaaa ctacaccaga
    11821 gttagagata gagatagaga aagatataga tatagataaa gaagaaaaga aaggtaagta
    11881 ttctgacgaa cacttacgcc ttgctaaaaa attgcaaagt aatttaactg aagattttcc
    11941 aaaagaaatg aacaaagtag atatcgaaaa atgggcagac acaatcaggt tgatggaaga
    12001 aagagataaa gcgtctatag aagcgattga gtatgtgatc aattggctac ctacaaatga
    12061 attttggttt ggaaatatta gaagtgctaa gaaattgaga gaaaaatttg agaagctcaa
    12121 attcgaaatc aaagcagaca agaataatca taaaaagcaa agtcaaaaac tacagtacag
    12181 caatcctagt gaatatgacg acttgccaat ttaaaaagga gatgcatcac atggaaagcc
    12241 tagcaaatgc tatggagaaa ctaataagaa gagtattagt gcaaagcggg aaatgtccag
    12301 aatgtagcga acctttgtat agttggcgag ctaaaaataa ggatggttca gaacgttgta
    12361 aaccaacatg catgagttgt ggttataaag cgttacgtgt gaaagaggat atacagaccg
    12421 aacggatata taacgacagc ttaaaagcac gagcgttgag tttttttcaa aatggttcgg
    12481 tattaacaga taaaactttg tttaaatgca aaatggagaa ttatcacgta gtggaccaag
    12541 aaacgaaaat tgctttagaa agagctaaaa gctttgtaaa tgatgtctta ctgaaccatc
    12601 ctgcacattt cattctatca gggaaatcag gaagcggaaa aagccacttg tcaatggcga
    12661 cagcttggga aatacttgag cgctcaaatt atgacaagaa aatacttttt ataagctatc
    12721 aagagttatt agagcaaata aagttttctt ataacaatgc tgaactgaga aaagaaattg
    12781 aaggatcgct tatagccgat atcaaaacaa ctgatttggt ggtttttgac gatattggag
    12841 ctgaattagg tagcggggta tcaaatagta ggcagtttac aaacaacacg ttaaacacgc
    12901 tcttagaagc cagacagaac aaggcaacga tcatcacaac aaacttatcc ggtcctgaac
    12961 taagagaagc ctacggcgaa agaattgttt ctagaatatt taagaattca gaaggttatg
    13021 cgctgaaatt ccaacaaaca gcagacaagc gcataaaacc agtgaaaggt agtatcgcat
    13081 gaataaatac cgtaataaga aaactgttca tcgaggtatc aagtttgatt ctatcgcgga
    13141 agcagagtat tacgatttag ccttgtggca agcagaagcg aacggctgga aagtaaaact
    13201 tcaggaaaga tttgagctga tgccgaaatt tgaactagat ggaaaaaagt atcgcaagat
    13261 cgagtatatt cccgacttca cattttataa aaacggcaaa cttgtcaaag tcgtagatgt
    13321 caaaggaatg cagacaaaag actttaagat caaggcaaag ttgttctgtc atcaatatca
    13381 agtgccgttg atattagcta aaaaatatcg gaatacgttc aaggaagagc gtttttaacg
    13441 aggtggtcca tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcaacgt
    13501 gagattgacg atctggaacg gataaaggca gtgatggtca atgaaacggc gagaaaggca
    13561 atcaatttgc acatagtgaa tttaagaagg gaaattcgta gattggagga atgagcgtgg
    13621 gtaagaaagc agcaatgaaa cgaatcattg aactgacaca ttctgagaat tggcaagaag
    13681 acaaagaaat agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccta
    13741 aacggaaaac gccgagaaaa attgcaatct ggcatggtga tcgaattcta gtaacgggta
    13801 cagctgaaca gttatctgaa attactggac tgagcaaaaa catcatctgg gatagagcta
    13861 ggagcttatg gattgattca aaggggcgac agtttaggta tgtggaggag aaataatgga
    13921 tctcattaca caatacagtg atatcatcct caagaaaatc atgatgaaga ttcagaaaga
    13981 taaaaaagca aaagaacgag cggaattagt taagttggaa atggctgaaa caggagcagg
    14041 agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat
    14101 tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact
    14161 tcatcaggat cgtttcaaat ttgtagaaaa gtatagagag atactgaatg agtatttcga
    14221 ggaggactag atgtttaatt caacgttagc gtcaattcac tttttattct atataacgat
    14281 atttgtagct atattaatta atgcgataaa aagcggtttt ttaacaccaa tcggcacaat
    14341 tttaacatta gcttcatttg ttacaagttg tattatccaa cttaaatata taaaggagaa
    14401 tgaataatgg acgaactaat cacaaaagta gagcagtggg ctaaagataa gggattggat
    14461 caagctgatt ccagcaagca aatgttaaaa acgatcgaag agatcgggga agttgccgct
    14521 tctctagcta gaaaagatga acatggttta agagacggaa ttggagatgt agtagtaacc
    14581 ttgattattt tagctatgca aaatgatatg gatttgtacg agtgtctgaa ccaagcatac
    14641 aacgaaatca aaggacgcac aggaaaaatg gtagatggtg tattcgtgaa gtcgagtgat
    14701 ttggaggaca gcaaatgatc agcctaacaa tattttggtg tgtaattggc ggcttactag
    14761 cgatgttagg agcatacctc atttacgaga gtgcaaaagg caaaaaatat acagcagtag
    14821 ggattatttt gtttgttgtc ggaattttag ttgcgattgg tgcagaaata aatctttatt
    14881 taaacggtac gacagaagag ttgatgtggt ttttattgtg gacaaggaga taggaggaca
    14941 gcgaaatggg cgatatgggc gaatactgga aagatattaa accgcatcta aaagaacgta
    15001 gaaaacaaca tgtcagaaag atgggcaatt cagcaactaa aaatattgaa accttgggat
    15061 ttgaatttac tcattatcca aacaatcatc aatttgcaat taatacccat aatggaatta
    15121 ttgactactg gggaactaca ggaacgtgga ttgagcgcaa aacaaaaaaa cgtggtaaag
    15181 ggatacgtag tttgaggaaa tatattaatc aggaggacag caaatgaact atacacaaca
    15241 agaactgact gatttatgtc caaaacatgt agctgagttc atcaataatg aagtcctgcc
    15301 taaatatgca gatggtttaa atacagcaga aaacgttaca gattttatga ttaatgatgc
    15361 tattgatcgt ttgatatttt tagaaataga ttgtattgct tattatcgtc tacacgcaga
    15421 agttgctttg attgatccgt atattgcttt aagccaaaat cgaaaaatac tcgtagccta
    15481 tattgatacc aaacagattt tagaaggcag agatgtcgag atagagatcg atgaggagga
    15541 agtgggatga aagcatacac aatcaagttt tatggaaata aaacctatgt atacatccta
    15601 agcggtctca gacttgattt tagaggctat tcaaaagaag accttttaga atccttatat
    15661 ggttacggat atttaaatga agatgaacta ataagcttag agaaatttac aaatgcttgg
    15721 acgattgagg aggaagcaga atgaagattt atgtagtaaa gttcgggaat aaattttata
    15781 gaagtgatga acgctctata ggggctaaca cattattcat tgtagacata ctccaaagtg
    15841 cgagatggtt tgatagcctc gaagaagcta accaagtttc acgacgactt ggtggattaa
    15901 cacaagtata tgaactggtc actgtcgatc atgaggaggt agaaagatga aattaaaaga
    15961 cggattttac gctagtagtc atggtatcgg cggtttaatg ctagatatgc cgacaaagaa
    16021 tcctaaaaaa cgtaagaaac caaaattcaa agtcggtgac atggttcgct gcgaagcaga
    16081 agggttcatc tatccatttc gtggatatgt agaacacgtc tataatcact cagcgatcat
    16141 tcgtattgaa aacacgatgg aatgtgataa gtggttagcg aaaagcaaag agaatttagc
    16201 tgtagcgaga ttggtggata tgaaggctat ataaacagcg aaaaaatgta cttctaagag
    16261 aaaaatttat tttttataaa aataggaaag tatcattatg aaaaagacca cagagataaa
    16321 taaacctacc acataaaaaa tgaatatttc ttgcgattca atataggtat atttaacaat
    16381 ttgtacaata aaaaatacta taggtaaaaa agataacatg aggagcttat ttgttctaga
    16441 gtgtttgaca aagtaacaaa atgcgacgat accaatacaa acgggaatcc aaaataacag
    16501 catgctccac atagtcactc aaccatctcc tatacgcttt attatcaata gataatatca
    16561 tttttcgtaa taaagataaa aaaataagta aggcttctca ttaaaatata aaaaagacag
    16621 ccgaccactg gctgtcctta gcagaatatt gaaatagtga gccatctgtt ttccgccaga
    16681 tagctcaaca tgtatatggg taacgagtgc aacctcgcta cttgaaaagc ttagcataag
    16741 catgggtata aaaaaagccg gattcctccg accttaatta ataattctga cacaattatt
    16801 atatcataaa tggaggaatc aatggatggt acttttcgat gtaaagaagt atgagacacc
    16861 agaggcaaaa gatgtggata tggatcgcac aaaacataat gttggtgttt ttctttcagc
    16921 atatctgtca gctagatgta ggataggtca acctcgggag cctaaagtaa cggcatctta
    16981 ctccttggtt ccaccttcta cagcaaataa tacatttgaa gcagaacgaa tgatgattga
    17041 gagagaggaa gcgcaagaag aatttgagta cttgcacaaa ttatttgttc gtggctattc
    17101 agcaattcag catccgcata aacctgatgt aacagaaagg cgcaagaaga tattctatga
    17161 tcgttatatc aatggtctgc ccatttatgt aactgctcaa aggaataata ctagcgaaga
    17221 atcggttaaa gtagaatcaa acagaattat catccaattt gcttcatcgt tagaactggt
    17281 tgcttttaag tagccagttt ttacactttt tatacccttt gattacccat ttggtttcca
    17341 ttttatacct tttttatacc aatcacttac ctggtaaatg atttattatg atagtgtcga
    17401 aagattagtg ataggtctga gacaaaataa taataaaagg aacatcgttt tattattgtt
    17461 tcacaattaa gcttcgatag acagcaacgg aaatattaag aataaggatg tgaattccaa
    17521 ctccttctaa attgttctta ttatctatca tccgttgctg tttattaatt tatgtattgg
    17581 agggaaaacg aatggaagtc gagcaaataa agtatcaagg tatggatcgg gaacggttga
    17641 ttgatattat tgagcaacaa cgtttagaat tgatccaaaa agaagctgta tgtaaagagt
    17701 acaaaaaaca tttagaacaa gtaattgagt atcattcagt agaaaagtac agatcagtgg
    17761 tgcaaaaaaa tagagcaacg agtcctgatc ctcgtcaaga tgtatcgatt agtatcaaga
    17821 cgccagtatt taattctgtt aaatcagaaa agctagaaag tatctcaact gctttggtag
    17881 aaaaagcagc tgaaatgaac tccctagcaa atgaagttag tcgtcttatt tagtcacatc
    17941 gataacttga gagtctttgg tgattccgtt ttttatagaa ttaatggttt gttcagcgga
    18001 atatttagtc aagtatgttt cgctagttgc tactacttca ttgttatcgg acttaataac
    18061 gaagtaatat tggccattag ttgcttctct tataacaaag tacaaatttt tcaccacctt
    18121 ttaatttatt tcagcggacc actcgctgat aaataaaatt atacacttag tatttatttt
    18181 cacaatatta atttgtcact gtggcggaaa gggtagacgc taagcatgtg tgttaggtca
    18241 atgcttcggc aaccatgcaa ggttcgattc cttgccagtg actttggcaa ctgagggttg
    18301 gaaatgggcg ctcaaagtac acgagcaagg cgaggtcgat agtaatcgat ggaatcggtg
    18361 taggttgctt gatagaacta taactgcatc tcgtttatga ggtgtagttt ttacatatta
    18421 gatcactcat cgagtggtct ttttattttg gaaggggagt aaaaaaatga acgaaaacca
    18481 attaagagag ttgtttaaaa cgaatgaagc aaacaaaaca atggaggcga cattctacga
    18541 aactcaaaaa agcttagcgt taatcgcaaa acaagctaag tatttctacg atcagcttat
    18601 tctgcaagga tttaatgacg cacaggctat ggaatttatg atgcgaacct tttctgccag
    18661 taaccaacag aaagagtgat acgtaatgag gaactactgg tatgtatcat tatcaaataa
    18721 atatccgcaa ccaaacgcag atgatccaat tagagttgtc cagtcagtcc agattaaaaa
    18781 gaagtactcc atcattgaaa tgaccagaga agctacgcca aaagagattg ataagtacaa
    18841 tcttcgttac tgcggccatg gatattttag tgagcagaac atacagacaa atattgagag
    18901 atattgttaa taaaattgaa aggtggtggc ttgaatgtgg taaatttgac accaaaacaa
    18961 aaagcttttg cggatgaata tataaaaaat ggtggtaatg ctactcaagc cgccattaaa
    19021 gcaggttata gcaaacgatc agcaagagta ataggtaagg aaaacctaac taaacctaac
    19081 ataatacagt atattaatga acggctaaat cctatcgaaa agaagcgcaa attaagtgcc
    19141 gaggacgctt taaatgaatt gatagatatt tggcaaggag aagtacaaat aagcgtgagc
    19201 aagcaaatag accgcttgga gaaaaacaag gttattaaac atatgcaata tgaatataca
    19261 ccagatttag aaagcaaatt gaaagccttg gatttgtatt tgaagtataa atcgctgtta
    19321 tcacaaacgc aattagaaaa agctcaaaca gaaataaaat taatgcaagc aaaattagaa
    19381 caattacaga taaactcaga gcgttctacc gaagaaaaac ttgatgagtt gttagaaaag
    19441 attagtggtg aattagatgg cactagttga tatttataac ccaaagcaaa tcgacgtgtt
    19501 aaataaaacc attaagaatg attggtttat tactttatta catggagcaa aacgttctgg
    19561 aaaaacaaaa ataaacaatg atttgttctt gtttgaattg cgacgtgtgc gaaagattgc
    19621 cgatgaagaa gacattaagg aaccaatgta tatcctagca ggagtttcaa gtgcaacaat
    19681 ccaaaagaac atcttacagg aactatacaa catgtacagc atagaaccta aattcgataa
    19741 acatggaaac tttaagctat ttggcgttaa ggtcgtacaa gcttatacag gaaacattgg
    19801 cggtgttggc gcaattcgtg gtatgacagc atatggcgct tatatcaatg aggcatcgct
    19861 agctagacaa gaagtatttg ctgaaatcgt ttcacgttgt tcaggaacag gagcgagaat
    19921 actagctgat acaaaccctg acaacccgga acactggcta aagaaagagt atatcgacaa
    19981 ttcaagcaaa aatattcaat cgttccactt tgaattagat gataatacat ttttatctga
    20041 acgatatcgt aacaatatta aagaatcaac accaagcggc atgttttatg atcgtgatat
    20101 caaaggttta tgggtttctg cagaaggtgt cgtttatcgt gattttgatg ctagcaagca
    20161 ctacatccag tcaaaagact taccaccttt gagcaacttt tattgtggtg ttgactgggg
    20221 atatgaacac tggggttcaa tcgtagttat aggtgaaacg gatgacggaa cagcttattt
    20281 aatcgaagaa catgctactc aatttgaaga gattgattat tgggtagatg tggcaaaagg
    20341 cattcaagag cgttacggct tacgagtacc tttttattgt gactctgcga gaccggagca
    20401 tgtggctagg tttgtaagag aaaagattaa tgctaaaaat gctcataaag cacggttatc
    20461 tggagttgag gaagtcgcca agagatttaa acaagataaa ttgtttatct gtcaagatag
    20521 agtgatgaaa tttcgggatg aaatttatca atacatttgg gacaagaaaa aaggcgagcc
    20581 aataaaagaa tatgatgatg tgctagactc cgttcgatat gcgatatata ctcatgagct
    20641 tcttaagaaa ccaaaagtta atgtcaacga aaagattaaa cgtattaaac gcatgtttta
    20701 aggagtgtga aaaatggata aggtaaacga gtttgaatac ggagctgata tacattattc
    20761 taatgacgtg aacacaaatt atgtaaagtt tagcgtagac tcaaatcttc actatagatt
    20821 tagctcagca gaagatttac ttaacgattt agatacttta gcagcaatga taaaacatca
    20881 tcatgaatat caggtaaaaa ggctaagtgt attagatgat tattataaag ctagaaatac
    20941 aaatatcatg gataaccgta ggcgcagaga aaaagaaaaa gcggatcacc gatcagcaca
    21001 taactttgga aaagttcttt gtacgtttga tgttgggtac aacacaggca atcctataaa
    21061 agtgcaaatc gaggacacaa atcaacaaaa agaaatcgaa ga
//
LOCUS       DACCVH010000047        21064 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.047, whole genome shotgun sequence.
ACCESSION   DACCVH010000047 DACCVH010000000
VERSION     DACCVH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.047"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            45..1211
                     /locus_tag="IVV98_001771"
     CDS             45..1211
                     /locus_tag="IVV98_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7807425.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            1441..2088
                     /locus_tag="IVV98_001772"
     CDS             1441..2088
                     /locus_tag="IVV98_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP7807426.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            2172..3116
                     /locus_tag="IVV98_001773"
     CDS             2172..3116
                     /locus_tag="IVV98_001773"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP7807427.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            3251..4702
                     /locus_tag="IVV98_001774"
     CDS             3251..4702
                     /locus_tag="IVV98_001774"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP7807428.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            4723..5574
                     /locus_tag="IVV98_001775"
     CDS             4723..5574
                     /locus_tag="IVV98_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP7807429.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SDVLSPN"
     gene            5555..6214
                     /locus_tag="IVV98_001776"
     CDS             5555..6214
                     /locus_tag="IVV98_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7807430.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            6340..7029
                     /locus_tag="IVV98_001777"
     CDS             6340..7029
                     /locus_tag="IVV98_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807431.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            7035..7991
                     /locus_tag="IVV98_001778"
     CDS             7035..7991
                     /locus_tag="IVV98_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP7807432.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            8035..8547
                     /locus_tag="IVV98_001779"
     CDS             8035..8547
                     /locus_tag="IVV98_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807433.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(8803..9351)
                     /locus_tag="IVV98_001780"
     CDS             complement(8803..9351)
                     /locus_tag="IVV98_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7807434.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(9440..10621)
                     /locus_tag="IVV98_001781"
     CDS             complement(9440..10621)
                     /locus_tag="IVV98_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP7807435.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(10857..12365)
                     /locus_tag="IVV98_001782"
     CDS             complement(10857..12365)
                     /locus_tag="IVV98_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP7807436.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            12524..12715
                     /locus_tag="IVV98_001783"
     CDS             12524..12715
                     /locus_tag="IVV98_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807437.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            12918..13835
                     /locus_tag="IVV98_001784"
     CDS             12918..13835
                     /locus_tag="IVV98_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP7807438.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            13828..14901
                     /locus_tag="IVV98_001785"
     CDS             13828..14901
                     /locus_tag="IVV98_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807439.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            15049..15567
                     /locus_tag="IVV98_001786"
     CDS             15049..15567
                     /locus_tag="IVV98_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807440.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            15548..15940
                     /locus_tag="IVV98_001787"
     CDS             15548..15940
                     /locus_tag="IVV98_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP7807441.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            16016..16951
                     /locus_tag="IVV98_001788"
     CDS             16016..16951
                     /locus_tag="IVV98_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP7807442.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            17084..17863
                     /locus_tag="IVV98_001789"
     CDS             17084..17863
                     /locus_tag="IVV98_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP7807443.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            17856..18173
                     /locus_tag="IVV98_001790"
     CDS             17856..18173
                     /locus_tag="IVV98_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP7807444.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            18417..20027
                     /locus_tag="IVV98_001791"
     CDS             18417..20027
                     /locus_tag="IVV98_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7807445.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            20184..21032
                     /locus_tag="IVV98_001792"
     CDS             20184..21032
                     /locus_tag="IVV98_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7807446.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         6850 a         3745 c         4214 g         6255 t
ORIGIN      
        1 tttagtatta acgtaatagg gtagtttttt taaggaggaa aatcatgtta gagaaaactt
       61 tatacaatca attattttca cgttctttct cgctccctgt cgaagtaaat tattgggacg
      121 gtacaacgaa acaatacgga gatacggaca ctcctcccca aatcaaaatc aatatccatg
      181 aagaaatccc aatgaaagag attacaagta acgcttcttt ggcactagga gaagcctata
      241 tggatcatcg aatcgagatc gagggaagta tccaagcatt gatcaacgat gcttatcagc
      301 aagcaaacag ctttttacga ggaaaagatt atctaaaatg gctgccaaag aaagaaaaac
      361 atacgaaaca aaaaaacaaa gaagatatcc atgcgcatta tgacttaggt aacgactttt
      421 ataaactttg gctagatcca actttgactt attcttgtgc ttatttcaat acacctgaag
      481 atacgttgga acaagcacaa atcaataaag tccatcatat cttagacaaa ctctttatca
      541 aagaaggcga aacgttgctt gatatcggtt gtggctgggg aacattgatg ttcactgcta
      601 ccaaagagta taatgtcaag gcaactggga tcacactaag tgaagaacaa tacgatttga
      661 ttaccaaaag aataaaagaa gaacatttag aagataaatg ccgtgtatta ttaatggatt
      721 accgcgaact aaaaggcgaa acgtttgatc atatcacaag tgtaggtatg ttcgaacatg
      781 taggttctga aaatcttgaa ggttatttca aagtggtaaa agatttattg aaaccaaaag
      841 gaacagcttt gatccatgga atcagccgac aacaaggcgg tgcgacaaat gcttggatca
      901 ataaatatat tttccctggc ggttatgtcc ctggtgttac tgaattagtt gataatatta
      961 caaaaaacga tttgcaactg attgatttgg aaagcttacg tcgtgactac caattgacat
     1021 tagaacattg gacaaagaat tttcatcaag tccaagatca agtcacgaaa gaaatgggtg
     1081 attccttcta tcgaatgtgg gatctatatt tacaagcttg tgcagcttca tttgaatcaa
     1141 gtaatatcga tgtgattcaa tatttgcttg ttcaacctgg aaacaatgac atcccaatgc
     1201 atcgtgcata attgaggcaa aagtactgtt taaagactat ttaaaaagaa gctaagtttt
     1261 atgatgctcc agaagtgaac ttttttgtct aacttctagg attgtctcta aagcttagtt
     1321 tctttttctt tatattttca taataaaagt ttggttcttt aatttttaaa catgacagaa
     1381 aattttttct tcgttatact tgtaatagaa tactatttta taacaaaggg gatcgaatca
     1441 atgaaaaaaa ctgttattta tactagttta tttgcagctt tgtttttagc tgcttgtcaa
     1501 tcaaatacca atcaaggcac atctgggaat acgtcttcca gtagcgaaca gcgctcttca
     1561 caggtatcgg actcctcaac aaaagcaagc acatcttcgt ctagccagac aaaaagttct
     1621 agtgaagcaa gtactcagtc agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc
     1681 caagataaat acccagatac tgcaattact agtttggaat tagatagtga ttggggatct
     1741 tacttctaca agatagaagg tgtcgatgat caaaaagaat acgaagcaag aattgatgct
     1801 caaaatgaaa aaatggagac agagaatcca gaaactctag atcgagatga acaaaatggt
     1861 caaaagaaaa aagaagatgg tctggatgtt gataaattga tcacgattga ggaagcagca
     1921 aaaatcgccg tcgacaaagt aggaagcggt acggcaacag attgggattt ggataaagat
     1981 ttaggtacta cttattggga agtcaaagta aaagacggca atcaaagtac atcagtcaag
     2041 atcaatagcc aaacaggcga agtactgtca actgaacaag atgattaaga atttcttcgg
     2101 aaaacaagag ttgatttttc ttttagtcat gatacactag acaaaataac ttgtttgaag
     2161 gagcgattta cttgagttta gaaacgacct ttgccaatca tatctttgcc aatcctttga
     2221 tgaatgcatc tggtgtccac tgcatgacta cccaggaatt agatgaactg gctcattcag
     2281 aagcaggagc atttatcact aagagctgta cgatcaatga acgaaaagga aatcccgaac
     2341 cacgctattt tgatgttcct ttagggagta tcaattctat gggacttcca aacttaggtt
     2401 tttcttatta tctagagtat gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac
     2461 cgttattttt ttccattgcc gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa
     2521 tagaaaaaag tgggtttaat gggatcactg aattaaattt atcttgtccc aatgtgcctg
     2581 gaaaaccaca actagcttac gattttgagg ccacttatga aacactgaaa gaagtattca
     2641 gcatcttttc taagccgcta ggaatcaaat tgcctcctta ttttgatttt gctcattttg
     2701 atcagatggc tgatatcttg aatcagtttc cattgaccta tgtcaatgct atcaacagtg
     2761 tgggcaatgg tttgtatatc gatacagaac aagaagcagt agtcatcaaa ccaaaagaag
     2821 ggttcggcgg cattggcgga gagtatatca agccgactgc tttggcgaat gttcgcgctt
     2881 tttatacacg tttgaaacca gaaatccaaa tcattggtac aggtgggatt cggacaggac
     2941 aagatgcatt tgaacatctg ctatgtggcg caagcatgtt acagattggt acagagcttc
     3001 ataaagaagg gccggaaatt ttttctagaa tcataaaaga attaacgcag attatgtcag
     3061 aaaaaggata tacgtcaatt gacgaattta aaggcaaatt acgcaccatt tcatagcaaa
     3121 gagacgaagg tcatgattga tcttcgtctt tttttataaa aaacactcgt ctgttcattc
     3181 ctgtgcaagc gtactcattg tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa
     3241 ggaggataat atgaatgatg caacagaatt agcaaaagag cttaaagaaa aagaatttag
     3301 ttttcaagaa ctagttacgg atatacagaa aaaaataaag aagcaaaatc atgaattgaa
     3361 tgcgtttgtc gcgcttgaac cattcgagag taattcccac gagctattga ttccccagtc
     3421 agaaaaaggg ccattggctg gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa
     3481 gggatggcta gctacttcag gatctcgttt atttgaaaca caccgagctt ctcatacatc
     3541 taattatgtg cggcaagcag aagcgatagg tctagttcct tttggacaaa ccaatgcgcc
     3601 agagtttggt ttcaaaaata ttacagaccc agtcatctat ggcccagcaa gaaacccttg
     3661 gaaccttgaa tgtacaccgg gcggatcaag tggaggagct gctgctgcag tttcatcagg
     3721 aatcgttcct ttagctggtg ctagtgatgg cggtggttct attagaatac ccgcttcgtt
     3781 ttgcggattg attgggctga aaccttcgcg agggacgatg ccagttggtc catatgcttg
     3841 gagaggatgg caaggagctg ctattgattt cggcttgaca gtttctatga gagacacgga
     3901 ggctttattt tatgggatga gaagtatcca ttccggtgcg ccatatcaag tatcgccagt
     3961 tgagtggcaa acacatccaa gaaaaaaacg gttgaagata gctttttgtg ttgattcacc
     4021 gatccactca cagattagtg aagaggcagt acttgctgta aaaaaagctg tagatttcct
     4081 tggaaaagaa gggcatgatt tgacagagat tccttaccca ctagatggtc gtaaactgat
     4141 cacgtcttat tatcagatga atggcgcaga aacagcagca atgatccgct cgattgaaac
     4201 aggcatccag cgagctgtca gaaaagaaga acttgaaccc atttcttgga ctttgttcca
     4261 atatggtcag aagctctctg ccgctactta catcgattct ctgcatgtat gggatgaagc
     4321 agcaattgtc atggaaaacc tacatcaaga atacgatcta ttcctttcac caacgactgc
     4381 atttaccgcc cctaaaatca gcgaagattt gcaaagtgat gcgataagag cacagatgga
     4441 acacatcagt gattgttctg aagtagaagg tttagacgtt gtttcttcca tgtttgagga
     4501 gagcttgaag atcacacctt atacacagtt ggctaatctg actggacaac cagcaatcag
     4561 cttgcctact catttgacaa aagaaaacat gcctctagga atccaattta tggctgccag
     4621 aggaagagaa gatttgctat ttcaaatcgg ctatctattt gaagcaaatc atcagttcca
     4681 tttaccaaat ccatggaaat agcagaaaca aggagaagaa gaatgaagaa aaaaagattg
     4741 tttgctctaa taactagtgc cttttttatt ttaagcgctt gcggtacagc tgccgctaat
     4801 caggaagata acagctggag taatgtagaa aaaaagaaag aattagtagt agcgacttct
     4861 ggcacactgt ttcccgcatc ttattataat gatcaaaatg aattagttgg ttatgatgta
     4921 gatttggcaa aagaggtggc taaacggtta aatgtcaaaa tctcctttaa agaatacaac
     4981 gtggatggac aaatcacttc tgtttcaaaa agagaatcag attttgctgc gaacgatttt
     5041 ggtatcacaa aagaaagaga aaaaaaattc tccctttcag agactttcaa atattcattt
     5101 gacagtatga tcgtacgaaa aaaagatgat tcaggaatcc actcacttga agatcttaaa
     5161 gggaaaaaag cagctggcga acccaatact agctatatgc gtttagcgga aaaacacgga
     5221 gctaaattag tcacatatga caatgccacg aatgatcagt atttaagcga tgtagcaaat
     5281 ggtcgaacag atgttattct aaatgattat tatctgcaga aaatggccgt atctgcttta
     5341 ccagatatcc ctgtaaaaat actggagaac gtttatttca atgaaaacga aagtggtttt
     5401 ttattgaaag aaggaaatga tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg
     5461 aaagaagatg ggacgacaaa gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc
     5521 aaaccgaaag aaacgatggc tgagtcggtg agtgatgtac tttcccctaa ttgatttttc
     5581 cctcatgtgg acttcacttc ctttcgtact gcaaggcttg gtatacacat tagggattgg
     5641 cttcgtgtcg tttcttttag gaaatttggt agggttgctt ttgacagttt taggtctttt
     5701 ggattggctg cctctgaatg tatttattcg tttttattta tcgttcttta gaggcattcc
     5761 cgcactagtc ctgctgtttc tgttatattt cgggttacct tatcaattaa gtgccttaac
     5821 ggcttcagtc atctgcttta cgattaccag cagtgcattt attggtgaaa tctatcgagg
     5881 atcactagca ggcgtttctt caggtcagtg ggacgctggt ttagcttctg gtttttcttt
     5941 ctttggggta ttgaaatata tcgttttgcc gcaagctttt cgaatctcag taccggcact
     6001 cagtaacgta gctatggatc tagtgaaagg tacttcgtta gcagcaacaa tcacagtgcc
     6061 agaaatattt caaaaagcaa agatcatagg cggtcggaca ttcgattatt tttctctcta
     6121 tattttagtt gcactgattt attgggtcat ttgtatcggg atcgaaaaag tgcaacagta
     6181 tttagaaaaa cgttctatcc atcagtcaat ctgaaaaata gaaatggtgc tagcgtggct
     6241 ggcaccattt ctattttttg tttcttgtat attctgccta gtattttaaa accatttcat
     6301 gtaaaatgta aatcgaaaat atgttcggag gtagaaaaca tgaagacccc gctaaccatc
     6361 gaaatagaat cctcgttata ccaatattgc atcgagcaag gcggcttggt tgtagaagaa
     6421 gtcacgatgc ctgatgacca aggaattgta gatacgctta gctgcttgac aaaatttgat
     6481 ggaagccgag aatggcgatg ctatgagctg aaagtgacaa aagcagattt tcgctctaca
     6541 gccaaactgt catttgttgg acattataat tattttgttt taccaagtaa actatatgaa
     6601 gaagtaaaaa ctgaaatccc tacaggaata ggtgttttag tgtatcgtcc gtacacggtt
     6661 gaagaggaga tgcctgcctc tggtacattt ctgattgcga aaaaagcagc aaagaaagag
     6721 cttgctgtac cggaagaagc tttgacaaac cgcttcatgg cttctttatt cagggaagta
     6781 agaaaagcaa agcaaatgga gcgaggcgta aaatattttc caaaagatca attgtacaaa
     6841 gaattgaaaa gacgttcaga aaatcaagat ccattttcta acgaacgata ttatgaacgg
     6901 tttttagagg aaatagctag tcaggcaatc aatgagttgc aagaagaagt tatcgcgctt
     6961 cagcatgatt atgaatattt gaggcaacaa cagcagatcc gtcggttgcc tacagagcca
     7021 ttggagtgaa aaatatgtac tatccttatt taagaggaaa acaatttgac ctattagcat
     7081 taaaagaagc actgtcgcga ggattgctct ccaataaaat ccaaccagtg atcgaaccag
     7141 tacgtgattc cgctacgctt aaaaatgtga tcgaattatt tcaaaaaaag caccatccaa
     7201 tcgctgtgat ccaaaatccc caagtaggac aattcaaatt attcgatcag catgtgcaca
     7261 gttggacagt caaagaaaat agctctgtcg tccctgcaca gatcttaacg ccagaaaatc
     7321 tcagtgaagt actggattca cctccagcgt ttcttgtttt cgatggacag cactacccaa
     7381 aagatacaga ggtgtggaaa cagttggcag gagttgattc gaaatttttg ataccagata
     7441 ctagtcgctt tcgcatctgg ctgcccgaaa acaaaattgt gatccgtgac tcttttcaaa
     7501 cgagaaagca tgttgaaagt tatgcagata aaacagatga cttttttagt gatgactatc
     7561 tttttttcca cgcagacgga tatattggat tttctgattt cacgatcgaa ggtagccgtt
     7621 atttcgataa agggttccct agccgagcgc ttgctatcca tctaacgtat attgatgctt
     7681 acggcaatat acgcgtgaaa cattttgtct ctgacagtaa cgactctgct aaagaccaag
     7741 cattgaagtt tcttgaagca ggagataaaa tgaaaaaatg gatcatgcgt caccatcatc
     7801 aactcttgat tacttcagga atgattgaat tattggctct ttaccagcaa caaaaattcc
     7861 ctggactggg agtgttgaaa aagtggtcac ttatgcatca tttggaactt attagtcacc
     7921 tgctagatca tccaaaagat tggcttaaat attattcaaa agttcaggaa ctatatgaag
     7981 tgatccaatg attagataat gtaaatgaaa aaggaataga aaagaggaaa ctggatgtat
     8041 attcggcaaa caaggaaaga agaagtagaa gaagtggtag aaatcattaa tgccgcagcg
     8101 gatttcattg cttcgcaagg ctctcctcaa tggcaaaacg ggcagaaacc aacaaaagaa
     8161 acgattttga acgatattga aagaaaagaa agctatgtat taatagtgga agatcaaatt
     8221 gctggaacag ctgcattagt ctcaggcgtg gatcccgttt acacaaaaat agatggtagt
     8281 tggaaagaat caactggtcc ttatttatcg attcatcgtg tcgctttagc agaaagtact
     8341 cgaggaaaaa aactagcaaa accgttctta gaacatttgt tgacgattgc agccagcaaa
     8401 aatatccaag atatccgtat cgatacttat ccagctaatg aaccgatgga aaagaccatc
     8461 tattctgctg gattcactta tcaagggatg attgaatttc cttttgaaca cggcgaaaga
     8521 aaagcatatc aaataatcat caattgacta taaaatcatc tgagcaaaga taaagacatt
     8581 aacactactg aaaaaaacaa tcatatgata gccaagaggt tgtaacagaa gtggccagct
     8641 tcaaaaaaca agaaagaatt tccgaaaatg cttctcaaat ttttgtggaa ttttagcgta
     8701 ttttacgaaa tagctgcttt ctgaaactcc cttcatcgag aggtcgtgac atagcttttg
     8761 tcacgatctc tcggcttatc ctacgagtat tattcgatac atttatatca ataatccttt
     8821 ttttatttta tctgcagctt cttggaacgc tccatcgttt gacacgacta aaagtgaggg
     8881 gatagctttc aaacgtttca actgtgctaa atcttctaca taaaccgcca gtctggctga
     8941 aatctgttca gatgaatctc cacgtttttt caggcgcgat tgcaatgttt ctttagagat
     9001 cgtaataaag ataggacgga ctaccgtccc gaaatactca tataaatgcc aaaaaccatt
     9061 tgctgtcaaa acggcgtaac aatttcctac tgtcagtttc tttttaattt ctgctttact
     9121 ggaaccatat ttatgttgag catattggtc ccactctgca aactcatttc ccttgatcat
     9181 ctgattgaat gtattgtcag aaacaaaata ataatcctct tgatcttttt ccccaggtct
     9241 tggtgatcga ttcgtgtaag taatgatctt ttgttccggc tgaaaaatag cttctgcgag
     9301 tgaagttttt ccagaaccag aaggaccgat aaatacatag caataattca ttgtcatttc
     9361 tcctttgatg attgaacaag tgaaaaagct ttggaaaata tttccaaagc ttttaaaagt
     9421 aactttgctt ttttgtattt tataccagca agccagtcac aatagcactt aaaaagctga
     9481 ctaaagtcgc tgttagcaaa attttcaatc cgtgttttgc gacaagattt cctttttctt
     9541 catttaatcc cttcatcgca ccagaaatga tcccgataga agagaagttg gcaaatgaaa
     9601 cgaggaagac agatataatt gctgttgtac gctcagtaaa atggaaatta ccatttgcta
     9661 attctgtcat agcaacaaat tcatttgtaa ccagtttagt cgccatgata ctaccggcat
     9721 ccactgcttc tttccatggg attccgctga tgaaggcaag aggggcaaag atgtaaccta
     9781 ggatctcttg gaaagtgatg ccgaatatcc cgtggaagat agcattgatc atggcaatca
     9841 aagcaacaaa accgataagc atagcagcaa ccgtgatcgc cacatggaaa ccatcaagaa
     9901 tgtattctcc caacatttgg aaaaatgtct gttctttgtt ttcttcaatg atcagctcat
     9961 cttctttttc ttctaataca tagggattta caattgaagc cagaatataa ccgccaaata
    10021 agttcaaaac aagggcagtg atcacatatt tagaatcgat cagtgccata taagatccga
    10081 cgatcgacat agaaactgta gacatagccg atacactcat ggtgaacaaa cgtttctcag
    10141 ataggaaggg taattccttt tttatggaaa taaaaacttc cgattgtcct aaaatagcag
    10201 aagctactcc attataagat tccaatttgc ccatcccgtt gattttactt aatcctagac
    10261 caacagcttt cataaataat ggaagaatct tgatatagcg tagaataccg ataatagcag
    10321 aaataaatac aattggcatc aatacggaaa gaaagaaagg tgcacttcct ttatttgcta
    10381 caccggcaaa aacaaagtca acaccttgcc cagcaaaagc aagaagatga tcaaacattt
    10441 ttgccaatac agaaacaacc gctgtaccaa aagttgtacg taataatacg aaaccaagaa
    10501 caagctgtaa aacgaacatc acaattagtg gtttcaattt gattgctttt ttgttactgc
    10561 tgatcaaaaa agcaagccct aatgtgacaa ataaaccaat aatacctaat aaataactca
    10621 aataatcact cctattccaa attccgtttt attttacctg ttttgcaaat aaaatactaa
    10681 tctttagtga aattttcatt acttttttag agtgaaacgc attcattttc cattagaaaa
    10741 taaagcgaac aaaataaaag gtttaaaaag tgtaacgtct tagtaaagtc tataaaaaaa
    10801 cgaaactatc gattaagcta atagtttcgt tttcaacatt tataagtaaa ctttttctat
    10861 tggtaatata gattttcgga agggtagaca ggtgcgcagg taatatcgat tcctagtttt
    10921 ttcaatgttt gttcatcatt tttattgacc atcacagtag agtgggcttg tgctccctca
    10981 agttcagcta gtttatcata agcaacttga gcgattggat tcgttactgc actgattgat
    11041 aaagcgatca agacttcatt gatgcttagt gcatccaaag aggaatgaag tgtctttgat
    11101 ttcaatcctt gtattgtttc aagaactaat ggtgacaata aaggaatgtc atctgcgata
    11161 tgggctaaat gttttactgc atttaagata actgccgctg acgcatccat caatgaactt
    11221 gtacgcccgg taatgatgac ttcatctggt aattcgattg caatcacagc agaaggatct
    11281 tttgtaggac tttgcgcttg aatcttatct gcatagtcat gggcagggac taccacgttt
    11341 cggtcttcag gacgtaaacc gacttcttcc ataatcagtt tgattcgatt aactgcttct
    11401 tcgtcgatca atcctttttt gaagtcgcat tctgtttgga aataacgacg gatgatttct
    11461 tgtttagagg cttcttggac aacggtatca tccacgatcc caaatcctac acgattcaca
    11521 cccatgtcag taggagattg ataaacagat tctttaccag taattttttc aataatacgt
    11581 ttgattacag gaaatgtctc aacatcccga ttatagttca cagctacttt attgtaggca
    11641 tcaaagtgga aggaatcgat catattgaca tcttttagat cgactgtggc tgcttcataa
    11701 gcaatgttca gcggatgttt caacggaaca ttccatactg ggaaagtttc gaacttggag
    11761 taaccagctg catgtccttt ttggctttca tgatacagtt ggttcaagca agtagcgagc
    11821 tttccacttc ctgggccagg agctgtcact acaacgattg gtttagttgt ttcaatatac
    11881 tcattttttc caaaaccatc ttctgagacg attttttcta cgttgactgg atagtcttcg
    11941 atttctgagt gtttatagac cttgatgttt cgtctttcta gtttattgat aaagactttc
    12001 gtggcaggct gtccactata gcgagtgata acgacactgt tgattaataa gccataacca
    12061 cgtaattcat cgattaaccg caagatatcc atatcataag taatcccata atcaccacgg
    12121 atcttattac gttcaatatc tccagcatag acgcaaatca gtatttcagc ttgatctttc
    12181 aatttttgca gcaatttgat tttcgcatct tcttcaaatc ctggaagtac acgtttcgca
    12241 tgcttgtcgt caactaactt cccaccaaat tctaaatata atttgtcata gtggttcact
    12301 cgttccaaaa tatacgctga ctgctcttca atatattttt ctgaatcaaa accaattttt
    12361 ttcactaggt tccctcctta agtactaaag cattttttca tttttttgag gattcgtcaa
    12421 ctggaagagc gaaattcctc aaaaaaacaa agaaaatggt ttaaaccaac ttgtctagat
    12481 agttattcat tggtatgata gtttttgata aggaaggtgc tacatgaaaa aaagacagaa
    12541 aaagaaaaac gcatataaac actatatccg ttcgattttt accggttatg aaagaatgct
    12601 tgaagatccc gaattggaac aattgacgtt tacttatcta aacgaagaaa cgcagctaac
    12661 tcgtgatgag catcagcgca ttcatttcac aacaagagat ctgcctagta aataaaaaat
    12721 aagataaagg tcatcggatt cgattctgtc ctatcagatg gaaagactag ttgatcgaaa
    12781 aaaaggctgt accaaatttt ggtgcagcct gttttatgga gcattgcccg ctctttttta
    12841 taacaatttt ttacagaaaa tggtactatt gaagtattaa taagtgaaaa acagatgagt
    12901 aagaggaggc aagtagtatg aaagagccag atacaaatgc aaattatgag ccagacgaac
    12961 tagaggagac gaacgcggat caggatacag gacaagaatc gtcttctttt tacgatatca
    13021 aagaaaaagc aagcatgaat ctttcccaat tattagaaga cttacaggct tttgaaaaag
    13081 ctgtccgcga agaagatatc cctgagatct accgtttata caatggccga ttgaatgaag
    13141 aattaaaaag aagctcaaat gaaaatcacg agatcgatca attgctgatg cgtaagatcc
    13201 atgatcgttt tttacaggaa tttcctttta tggaacaagt agaaaacatc tcgccaacga
    13261 tgagctatta caaaatcggc acttattacc atgatcggcc cacggtcggt attgatgcaa
    13321 gtctgccaga aatttttgtt ttgcctaaga tcgatgaaga gtgggagaaa tattcccaac
    13381 cggagtcaac ggactatgac aaaaaaatca atgagctaga cgcaaaggtg atcactgctc
    13441 agacagaaat tgaacgttta gatgaacaaa taaaagaaat caatcgacaa atgactgatt
    13501 tgaacgacaa taaaggattc ttgaatcgta aaaaaatcga ggaagaaatt caagaattag
    13561 agaagaagaa gcaagtacta tctaatgaaa aattaggctg gcttccttat attgagacgc
    13621 ctgaaacaat ccagcagcaa aaagaagcat tgaagcaaga agcaagagca gaccagcttc
    13681 gtgcagccat cgtagaaaaa gaacaaaggc aaatcagacg ctatttcggt agcaaagagg
    13741 gattcggtca agcaatccat gaattcttga tgaattatct tggcaatgag aatcctaata
    13801 atcaatctaa tgaaggaggt tccgagtatg aatgaacacg atgaagcaga atggacaaaa
    13861 aatgaagaac aaacagaaga tcatgaagaa acgaacactt cattggaaga acaaacaagt
    13921 aatcctctgg atgacacaga agaaatccct atgctagagg aaacaaaaat acatgaaaaa
    13981 gaaaaagtaa ctccgacgaa tacgaatact gcagaaaaca cccatgctta cgaaataact
    14041 gaaaatcccg ggtatttaga aggaaaagag caagatcatc aagatatcgt cagtttgatt
    14101 gaaacagcgg aagcagaatt agcggattta cgtatgagaa aagatttgat cgaatcagat
    14161 tttccacaat tattagaatc atatgatcgt tttatattga atgaagaacc aatctccacg
    14221 atcggaaaga caagcctgat cgaatacttc acgtatgaat tactgaaacc gttgaatgat
    14281 attggtctgg aacggtcaaa ttcagcttat gacacatgga aaacaagaca tttttcgatc
    14341 aattatacgt tgaatggaca aaacgaatta gtcttttcct ttgtattacc gaccatcgat
    14401 caacgatacc aagtggaatc gatgagtctc ctaaacgtat caccagagac aatggaaatc
    14461 aatgtccaag atgaccgggt gctttctttg atccgacact ggtcagtgga tcgagtattc
    14521 tctgcagggc agatcacgat attcaatcac aaattgaatc aattattagc ccatgcaaga
    14581 acacttggtt ttaccgttaa tcagacatta ctagacaata cgaagccact tcgtttgaat
    14641 cttcagagcg aatttgaatt gacgaatgaa gtattggatg atatttttat cgtggcaatg
    14701 aaaaatccat cctacgatat ggaaaagatc aacgaaacta cttatcaagt acgattagat
    14761 aaaggacagt ctttaacgat aacaacaaac gaaaaagatc aaacagtctt gtcgatctca
    14821 tctggagact acccacgatc tgtcattgat ttctttatca attacgaatt cttggtccca
    14881 ttaatggtga gaaagtcctg attggataag ttggattacc agatgtcatt cagataattc
    14941 tgttccaaag gacttgcggc agttatccag aataattgtc acaagtcttt tctgtatgta
    15001 ctaaatggac gtgaataact tgctgatgaa ggagggattt cattaggaat gtccacaaat
    15061 aaaatagcac agcttagctt attgtctgct gcttgtgtag caggtaggat cgcttttcaa
    15121 tttattccga atttccagcc aatgactgct atttttttat ttatagtact ttacttaagc
    15181 ttaaaagatg cgttaattgt catgagtctt tctattgcga tcagcagttt ttattttggt
    15241 gttggaccat gggtcatcgg ccaatggatc agctatactg ttgttctgag tttgttttca
    15301 atcgtctgct tgagaaaaac agtgcaaagg aatctatggt taaagggagt ctgttttttt
    15361 ctggcgggca tggtttacgg aataggtatg accgtttttg atacgctgtt atatcgtttg
    15421 cctcaacctt ggatctatta ccttcaaggg gtgtcgtttg atttgatgca cagtataggc
    15481 aatgttgtgt tctttcttgt ttttctgcca gtcgtcaaac gtttttacaa tcattcagga
    15541 ggaaaaaatg aaaaaaataa tttatagttt gcttgcaatg agtgtcagta tactcatttt
    15601 gacaagttgc agtacaacct atacacaatc ggcttccaac caaaaggagg aagtaaaaac
    15661 atcgcaaaaa gcaacaatca cgttacaaga aaatggtcaa aacttttcgg aaaaagaagt
    15721 ggtcttcaaa aaaggcgatg atttactgag tattttgaaa cgaaattttg aagtcaaaga
    15781 agataacggc ttcatcactt cgcttgaagg gcactcacag gatgagaaaa atcaactcta
    15841 ttggatgttt actgtggacg ggaaaagtgc tactactggt gccaaagaga tcaaattgaa
    15901 tgatggacaa tcggtcattt tcaatttgtc taaactataa gtttcataaa aaactgttaa
    15961 agggcgaata ttgccataat tcagtgagtt cagttgatga aagaaggaaa ataacatgga
    16021 aaattttaaa aaaagcggaa tgttttccgt aattgctgct ctaggggcta atattctagt
    16081 tgctatcagc aaatttgtcg gctatgcaat cagtggcagt gccgccatgc taaacgaaag
    16141 catccacagt atcgttgatt gcagcaatca gattttgctg ttattcggtg ataaacaagc
    16201 caataaagga cagagcgagt tgcatcaatt tggtgaagga cgagcaaaat actttttcag
    16261 tacaatcgtc gcaatgatgc ttttcttcgg cggtggggca cttggggtga tggaagcttt
    16321 tgaaaagttg acgcatccat cccatgaagt gggtaatccg atcattgtta tagcaatact
    16381 gttatttggt ttggtaatcg aaggaagttc gttacgcgtg gcaatgaaag aaatcaaaga
    16441 attgaatact gaaaaacttt ccacgatgcg ctttttgcgc gaaagtcgac acagtgaaat
    16501 actgattatt tttacggaag acttgtgtgc tgtaatcggt ttggtcttgg ctttagcagg
    16561 aacaatattg acttatgcaa ccgggattgc tgcatttgat gcgatcagcg gattgctgat
    16621 cggtttcttg ctgatgggag ccgccatttt cctagcaaaa gaattttata gtctgatcat
    16681 cggtgaaagc gtgacagcaa gcgatttatc aaaaatcaag ttagcttttg aacgtcctga
    16741 gatcagtcgg ctgatcgata taaaaacagt tcatttaagt ccaacggaga ttttagttgc
    16801 agcaaaagca gatatcgttg gtaacaaaga gaatgaagct tactcggtca tcaatgatat
    16861 tgaaaaaaat atgcgtcagt ctcttcctga caagaagatg tatatataca ttgaaacaga
    16921 taaatatgac ccaaattatt ctcgtaaata aaacgtttat tcatgaattg aagcaaaaat
    16981 gagaaaaata taatcttgtt tttaaataaa acggctacaa tttagcgaat ttatgttaca
    17041 atgagtccgc tgtttatttg ttgtaattaa aggagatatt ttaatgaaca aaaagaaaag
    17101 tgcgccatgg cttcaagctt tgcatgcagt gatgccactt tgtataagct atataccagt
    17161 aggattagct tgcggagtat tgttgcaaaa agttggattt gatcctctct tatcaggact
    17221 gttatcgatt ctggtctttt ccggtggcgc gcagttttta gttgcatcta tgcttacgac
    17281 gcaagcatca tttgcaacga cattattgat ggttttcttt ttagaattac gctatacatt
    17341 attaggagca agtcttgccg gttttatgaa aaaagaaaag cggacgtttt tggctgtctt
    17401 ttctcaatca ctgaatgatg aaaactatgc ggtgaactac ttaaagtttt caactgaccc
    17461 ttcctggaat aaaagaaagg ctttatatgt caattggttc tcaatgactg catgggccgg
    17521 tagcaatatg atcggtaatt ttttcggctc ggtgattcga gtagatgctg accttgtcca
    17581 ttttgctttg acggccatgt tcattttcat gtttatcatg cagatgaaaa gcgcactact
    17641 gatctttaca ggtttattct caggcgtatt aggggtcgta ttcatggtat tattccaaaa
    17701 tactttcgga ttgattgcag caacagtcat tgcttcattt gccggattta tgctggagaa
    17761 ggcattcaaa aaagaaaaag ctaagaaact aagagaccgc ggtaaagatg tcaatgagcc
    17821 gctcttcaac ttcccggaac aggaggccaa tcaccatgac taaactatat ttgctacttt
    17881 tagttgcttg tctgttcatc gtggcatata tcccgcgctt gttcccgatg ctttatttta
    17941 ctcatcgaaa agtgccatcc tggttcagtg actggatgaa atatgtaccg gtggcattat
    18001 ttgcggcgtt agcttttaaa gatgttttca ttactcatga acatctggat attgcttgga
    18061 atatcaaaat agctgcaatg attctagtag caggcgtggc ttacaaaaca cgttcgatgg
    18121 cgttgtcagt tttgacagga cttgcgtctg tctttttgct gtctatgctt taaactgttt
    18181 tattttatta aaaacagaga ttgcgacata agttgttcaa actgatctat ccgaactgca
    18241 tttgcaacag tcaattctgg atgcaagttt attcgtaggg ataaaaaaga ttagtgttgg
    18301 cttatgatgc aagctctttt ttattttagg aattagagag ggatttgtcc ttctatgatt
    18361 ttttgctata atagggaaga tgtttatttt atgaaagaat agttgaggga atttaaatga
    18421 ataaaaaatt gatgcaagga acattttggc taacctttgc taatcttcta tgtaaagttt
    18481 taggggtagt ctatttgatt ccctggctaa gtatgatggg gaacaatcaa gatggtatgc
    18541 ttgctacgac attgtataat gttggctatc ttccttatgg attgttcctg atgcttggta
    18601 cagtcggatt tccaaatgcg attgcaaaaa aagtagctgt agccacaaaa gaaggagata
    18661 acgctgcttg tcggctgatt tttagaagta cgatcaatat catgtttgtc atcggtatcg
    18721 cctctgctgc actgatgtat ttatttgctc ctttactagc cggaatcagt ccgattgcta
    18781 acgttaataa tgggatacta gctatcagaa gtttatgccc atctttgatt gctatcccaa
    18841 ttcttagtgc aatgagagga tatttccaag gaaaaaatga tctgcggcct tatggaactt
    18901 ctttgattat cgaacaggct gtgcgagtga tcgttatctt ggctggtact tattacttgc
    18961 gcgtattgac tgacggaacc atattagaag ctgtattgat cagtacagtc gcttctttct
    19021 tcggtgggtt agctgcgatt atccatatgt atatcgtcgg acgcagaaaa gacttcttcg
    19081 aacttaaaga ttttttgatt tccagccgtt atttcgaaag agaaaaccga tctgcctctg
    19141 tctctatcat tcgggaaaca ctaccgttta tttttgtcgg ctcagtcatt actatcgttc
    19201 aaatgatcga ccaagtaacg atgaaaccac tgcttcactt tttccgtcca gagatcgcag
    19261 atcagcaact ggaattctta ttcagccgtg cttctgtcaa tccaaataaa ttgacattga
    19321 tcctgatctc catggtagga acagtagcta taagcagctt gccaatatta agcacgatga
    19381 agaaaaaaga tcggatacaa atcgaaaaaa cagtaggaga tagtttttcg attgcgttat
    19441 tgattcttct tccttcattg actggaatgt ctttattagc tggaccacta tacacattgt
    19501 tttttggcta tgatcctgaa agtgtcggat atttccaaat ggctttgcta gcttctttgt
    19561 ttttctcttt attcacgatc ctatctacga tgcttcaatc tttgaatcac catcgttttg
    19621 cgatccgatt aactgtagaa gcaattatcc tgaaagtcat cttccaagta atcggattag
    19681 gattagttgg cggatacggg atgagcttat caaatggctt agcattcggt attgtctttg
    19741 ttcgcggcta tcactttatg tgcaaagaat accgaatagc acctttagca aagatcagca
    19801 attttttctt aaaaactttc cgctccaccc tgattatgct tgcagtatgt tttgccgttt
    19861 tctttttgct gaatcagcga ttgtcaatgg aatcaaaaag ctatgcaatg atttattgtg
    19921 tggctgtagg aagtattggc ggcttagtat ttttattttc tcaattcgga aaaaatgggt
    19981 ttcgaatgtt gaaaaatgtt aaacatcata gcagaagcaa agaataggtt aactaatcgt
    20041 tttttgctgt cacttgaaaa acggcaactc gtatgattac gcttgtcgtt tttctatttt
    20101 ccaattttag tttcatatct aatcttactt atgatatagt tataaggtct ggaaaaattc
    20161 tttgaaacga ggaaattaaa cacatgaaac ttgcagtagt tacagatagt tcggcatatc
    20221 tgccggaacg tatcaagaac catcccgact tattcgttat tccaatccct ttgattatgg
    20281 atgggaaaat ttataacgaa ggaatcgata tcgaagcgga tgaatattat ggacttttaa
    20341 aaaacagtaa agattttcct actacttcac aacctgtcgt aggggaagtt ttgggtttat
    20401 atgaggaatt gaaagagaaa gggtatgaca cgattttaag tatccatctt tcttcaggga
    20461 tttctggctt tgtcaacaca ttatttgcga tgaaagatga catcagcgga gtaacggtca
    20521 ttccttatga ctctaagatc actagtatgc cgatgggaca catggtagaa gctgccttag
    20581 acttaaatga tgaaggtcag tcccttgatg aaatacttgc acatatcgat cgaatccgag
    20641 ataataccta tgcttatctg attgtagatg atttgaacaa tttagtacga ggaggacgtt
    20701 tgacaaatgg tgcagcgctg attggcagct tattaaaaat caaaccgatc ctgacatttt
    20761 ctgaagggaa aattgtttta ttcgaaaaaa tccgttcaag taaaaaagca tttgctcgag
    20821 ctgaagaaat tattggtaga agaaataacg aaatacaacc gccagtcaaa ctttacgtga
    20881 tacatgcaaa taatttagaa gtagcgattg cggagaaaga gaaattgcag aaaaaatatc
    20941 caaatgcaga aatcgaaatt ggtcatttcg gaccagtcat tggtacacat ttaggtgaaa
    21001 aagccatcgg cattgccatt tcagcgcaat aattcctttt attcaaaaaa cataccaaaa
    21061 atat
//
LOCUS       DACCVH010000048        20767 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.048, whole genome shotgun sequence.
ACCESSION   DACCVH010000048 DACCVH010000000
VERSION     DACCVH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.048"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            352..1041
                     /locus_tag="IVV98_001793"
     CDS             352..1041
                     /locus_tag="IVV98_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7807447.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="IVV98_001794"
     CDS             1028..2236
                     /locus_tag="IVV98_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7807448.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="IVV98_001795"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="IVV98_001795"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP7807449.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVV98_001796"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVV98_001796"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP7807450.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="IVV98_001797"
     CDS             complement(6339..7034)
                     /locus_tag="IVV98_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP7807451.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="IVV98_001798"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="IVV98_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP7807452.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="IVV98_001799"
     CDS             complement(8233..8424)
                     /locus_tag="IVV98_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP7807453.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="IVV98_001800"
     CDS             complement(8445..9335)
                     /locus_tag="IVV98_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP7807454.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="IVV98_001801"
     CDS             complement(9322..10089)
                     /locus_tag="IVV98_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7807455.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="IVV98_001802"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="IVV98_001802"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP7807456.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="IVV98_001803"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="IVV98_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP7807457.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="IVV98_001804"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="IVV98_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP7807458.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14705..15043
                     /locus_tag="IVV98_001805"
     CDS             14705..15043
                     /locus_tag="IVV98_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807459.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="IVV98_001806"
     CDS             complement(15211..15969)
                     /locus_tag="IVV98_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP7807460.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="IVV98_001807"
     CDS             complement(15987..16805)
                     /locus_tag="IVV98_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP7807461.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="IVV98_001808"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="IVV98_001808"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP7807462.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="IVV98_001809"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="IVV98_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP7807463.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="IVV98_001810"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="IVV98_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP7807464.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="IVV98_001811"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="IVV98_001811"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP7807465.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5950 a         4225 c         3808 g         6784 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttatt
//
LOCUS       DACCVH010000049        20689 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.049, whole genome shotgun sequence.
ACCESSION   DACCVH010000049 DACCVH010000000
VERSION     DACCVH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.049"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            110..304
                     /locus_tag="IVV98_001812"
     CDS             110..304
                     /locus_tag="IVV98_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807466.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            573..872
                     /locus_tag="IVV98_001813"
     CDS             573..872
                     /locus_tag="IVV98_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807467.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(969..1403)
                     /locus_tag="IVV98_001814"
     CDS             complement(969..1403)
                     /locus_tag="IVV98_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807468.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1635..2345)
                     /locus_tag="IVV98_001815"
     CDS             complement(1635..2345)
                     /locus_tag="IVV98_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP7807469.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2335..3195)
                     /locus_tag="IVV98_001816"
     CDS             complement(2335..3195)
                     /locus_tag="IVV98_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP7807470.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3200..3838)
                     /locus_tag="IVV98_001817"
     CDS             complement(3200..3838)
                     /locus_tag="IVV98_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP7807471.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3853..4152)
                     /locus_tag="IVV98_001818"
     CDS             complement(3853..4152)
                     /locus_tag="IVV98_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807472.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4195..5679)
                     /locus_tag="IVV98_001819"
     CDS             complement(4195..5679)
                     /locus_tag="IVV98_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP7807473.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5699..6160)
                     /locus_tag="IVV98_001820"
     CDS             complement(5699..6160)
                     /locus_tag="IVV98_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7807474.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6178..7245)
                     /gene="ulaG"
                     /locus_tag="IVV98_001821"
     CDS             complement(6178..7245)
                     /gene="ulaG"
                     /locus_tag="IVV98_001821"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP7807475.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7463..8233
                     /locus_tag="IVV98_001822"
     CDS             7463..8233
                     /locus_tag="IVV98_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7807476.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8506..9333)
                     /locus_tag="IVV98_001823"
     CDS             complement(8506..9333)
                     /locus_tag="IVV98_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807477.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9901..11136
                     /locus_tag="IVV98_001824"
     CDS             9901..11136
                     /locus_tag="IVV98_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP7807478.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12135..12395)
                     /locus_tag="IVV98_001825"
     CDS             complement(12135..12395)
                     /locus_tag="IVV98_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP7807479.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12422..13723)
                     /locus_tag="IVV98_001826"
     CDS             complement(12422..13723)
                     /locus_tag="IVV98_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807480.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14015..14473)
                     /locus_tag="IVV98_001827"
     CDS             complement(14015..14473)
                     /locus_tag="IVV98_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP7807481.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14486..15811)
                     /locus_tag="IVV98_001828"
     CDS             complement(14486..15811)
                     /locus_tag="IVV98_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAP7807482.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15828..17240)
                     /locus_tag="IVV98_001829"
     CDS             complement(15828..17240)
                     /locus_tag="IVV98_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7807483.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17257..18021)
                     /locus_tag="IVV98_001830"
     CDS             complement(17257..18021)
                     /locus_tag="IVV98_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP7807484.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18125..19000)
                     /locus_tag="IVV98_001831"
     CDS             complement(18125..19000)
                     /locus_tag="IVV98_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7807485.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19255..19339)
                     /locus_tag="IVV98_001832"
     tRNA            complement(19255..19339)
                     /locus_tag="IVV98_001832"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19303..19305),aa:Leu,seq:caa)
     gene            complement(19357..19428)
                     /locus_tag="IVV98_001833"
     tRNA            complement(19357..19428)
                     /locus_tag="IVV98_001833"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19394..19396),aa:Gln,seq:ttg)
     gene            complement(19438..19510)
                     /locus_tag="IVV98_001834"
     tRNA            complement(19438..19510)
                     /locus_tag="IVV98_001834"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19475..19477),aa:His,seq:gtg)
     gene            complement(19572..19656)
                     /locus_tag="IVV98_001835"
     tRNA            complement(19572..19656)
                     /locus_tag="IVV98_001835"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19620..19622),aa:Leu,seq:caa)
     gene            complement(19677..19747)
                     /locus_tag="IVV98_001836"
     tRNA            complement(19677..19747)
                     /locus_tag="IVV98_001836"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19713..19715),aa:Cys,seq:gca)
     gene            complement(19793..19864)
                     /locus_tag="IVV98_001837"
     tRNA            complement(19793..19864)
                     /locus_tag="IVV98_001837"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19830..19832),aa:Gln,seq:ttg)
     gene            complement(19876..19948)
                     /locus_tag="IVV98_001838"
     tRNA            complement(19876..19948)
                     /locus_tag="IVV98_001838"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19913..19915),aa:His,seq:gtg)
     gene            complement(19951..20024)
                     /locus_tag="IVV98_001839"
     tRNA            complement(19951..20024)
                     /locus_tag="IVV98_001839"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19990..19992),aa:Trp,seq:cca)
     gene            complement(20031..20111)
                     /locus_tag="IVV98_001840"
     tRNA            complement(20031..20111)
                     /locus_tag="IVV98_001840"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20075..20077),aa:Tyr,seq:gta)
     gene            complement(20113..20188)
                     /locus_tag="IVV98_001841"
     tRNA            complement(20113..20188)
                     /locus_tag="IVV98_001841"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20153..20155),aa:Phe,seq:gaa)
     gene            complement(20224..20296)
                     /locus_tag="IVV98_001842"
     tRNA            complement(20224..20296)
                     /locus_tag="IVV98_001842"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20261..20263),aa:Asp,seq:gtc)
     gene            complement(20306..20378)
                     /locus_tag="IVV98_001843"
     tRNA            complement(20306..20378)
                     /locus_tag="IVV98_001843"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20343..20345),aa:Val,seq:tac)
     gene            complement(20394..20465)
                     /locus_tag="IVV98_001844"
     tRNA            complement(20394..20465)
                     /locus_tag="IVV98_001844"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20430..20432),aa:Glu,seq:ttc)
     gene            complement(20480..20569)
                     /locus_tag="IVV98_001845"
     tRNA            complement(20480..20569)
                     /locus_tag="IVV98_001845"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20533..20535),aa:Ser,seq:gga)
     gene            complement(20609..20682)
                     /locus_tag="IVV98_001846"
     tRNA            complement(20609..20682)
                     /locus_tag="IVV98_001846"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20646..20648),aa:Asn,seq:gtt)
BASE COUNT         6533 a         4337 c         3285 g         6534 t
ORIGIN      
        1 aactttcaaa ttgattcttt ttatttatca taaagatata gatacataat cattttcact
       61 tacatatatt tgaatattaa ctaaaaacag caagaaagaa gaggatcaaa tgtattatgt
      121 agaagtaaaa acaaaaggcg tcaaaaacaa acaatatgtg aaaggtatca gtaacgaata
      181 tcctttactt ggttcatgga aagaagctgc tcctttttcc aaaccatgtg ccataaaaat
      241 aaagaacgag ctagaaaaag aactgacttg tggtaaagct gttgtagata tcatcgaaaa
      301 gtaaatccaa tgtatagaaa ggaagatcac acatgaaaag cgacgtacaa attgctaaga
      361 ttatagaatt agaagaagaa gacgcagtgt tgacaattga aaaaaaataa atgtttgtat
      421 accatatgat tatttcaata tgtatcctgg aattggagat ctcgtagagc tatatcaaga
      481 tgaatcaaat atacttgtca ttcatcatga aatatagaga cttataaaat tgtttatttt
      541 tataatgtat cagtatagaa aggaaataaa acatggatta tactgttgaa tttgacagtg
      601 aactacttaa gcaatttcca caagaagaac atttcatgta taaagaagca atttcccaca
      661 aagtgacaga gtatttggag cataattttt ttcgtataaa gccagtgcgt actcgttcgg
      721 caaaaggaat atacgagatg aaagtcaaaa ttaataaaaa aaattatcgc atagcatttg
      781 ctttaaaaaa aaatcatgtg ttcatttttt atattagttc gaatttgcaa aaaattgtat
      841 ttgataaaga ggtgagtaaa aaaataaaat agctgagcat tggaggatag attgagtgat
      901 actaagtcta tcctcttgtt tttctaaaga actaagctag aattttttct tttgtacgtt
      961 attatatgtt atttgtcatt accaaaaagc accttttttc ttctagtatc tatgacataa
     1021 gaaataccac ccatttcctt tacttgaaca aatcctactg attcataaaa tttttttgtt
     1081 ttctcagtat catctgtcaa taattcgatt tggactggtc cataactagt gatcttctcc
     1141 aaagcttcat tcaaaagcac tttgcctatt ccttggcgct gatacctcgg atgaatgagg
     1201 atatcttgaa taaatgcgat cgtcgcaaaa tcagtgatcc aacgaacgat tccgataatc
     1261 ttcccttccc cattacgctt tatcagagat tcagattgtt caaatgctct agctaacctt
     1321 gcagtgtctt ttgtgtaatt cgtccaacca acgctcttat ataattcaga aatctcatcg
     1381 atcataaggg aatcaatatt catttttttc ttcctttctt atacaattct ccctctaata
     1441 atacagttct ttgactattt aatctatcac atataactct cctgtaaaga ttctctcgat
     1501 tccttaaaat tcctctttcc ttttagaatg catacttttt gataaataaa aaggttgtga
     1561 taaattttct tcacaacctc tgtttctctc tatcaagtgt tatcttttaa ttttctaccc
     1621 ttaccctagc atctctattg cccgtagtat gcatactttc catgtttgcg aaaataatgt
     1681 ttatctagta aatattgcgg gatttcacat atattggggt tgatcagctc gttttctttg
     1741 gccatcagac aaatttcatc taagatcaaa ctgttttcta ctgctttcat aggtgaatcc
     1801 ccccatgtga acggtccatg tccatagaca agtactccag ggacttcgtt tggatctaat
     1861 tttctttcct taaacgtctc gacaatcaca ttccctgtat gaacttcgta agcttctctt
     1921 acttcttctt tcgttaattg gcgtgtacaa ggaaccttac cataaaaagc atcagcatga
     1981 gtcgtgccat aagctggcaa atcgcgtcct gcttgcgccc acatgacgga gtgcgtggaa
     2041 tgagtatgag taatagcagt tatatcttca aaagtttgat acaaaacaac atgtgtgggg
     2101 agatctgaag atggttttaa gctatcttct tctattatat ttcccgacaa atctgttacc
     2161 accatttgat ctgcttgcat gcattcatat ctgacaccgc ttggcttaat gacgatgact
     2221 cctagctcac ggtccacttc actcacattg ccccaagtca atttgactaa tccgtatcgc
     2281 ggcaatgcca gatttgcttc aaggacacgt tgcttcattg ctgcaatttt ttcttcacaa
     2341 gacatcatag ccagcctcct tcaatttaga acttaagtag tcttttgcct gctggatttc
     2401 tcttcgaaag tcttggcttt tttcactcca catttcaatc agaaatgttc catcataatc
     2461 tagacgtttc aaatgtctta ataatccaag aaaatcaaca caaccgctac caaaaggaac
     2521 atcacgaaac tggcctgaat attcttttgt tacagggtaa gtatctttta agtggatagc
     2581 agtgatataa tcgatccctt tctcaagttc tcgagccgga ttattttccg gccatgcgga
     2641 caaattgcct aggtctggat atacttgtag aaaaggtgaa tgaatctgtt ctttgatttc
     2701 taaaaatttt gaaatggagt tcataaatgg atcatccatg atttccacgg aaagaatgat
     2761 gccatattta gaagcttcct ttacgctttc ttttattcct tcgataaagt cttctctgga
     2821 attcattgat ttctcttcat aataaacatc gtatccagct atttggatta ctttgacgct
     2881 tagattatgc gccaaatgga ttgctttttt cattagttgt ttcgctgctt ttttcttttc
     2941 tggatcagca gaaccaaacg gaaatcgccg atgcgcactt aaacaaatcg aatggatacg
     3001 tacaccggag ctgaacatct cttctctcag ctcagctatc ttttcttcag accaatctaa
     3061 tcgtgctaac cgctcatccg tctcatcaat cgacatctcg ataaaatcga agtccatttc
     3121 ttttacaagg gaaaaacgtt ctttccatga aatatctttg ggtaacgctt tttcataaat
     3181 cccaatttga gccatttcct tacccccaga tacgaatgat ctcatctttg aagttttgtg
     3241 cggccttcat cggatcattt gctgctgtaa taccacgacc agtgataaag gtatacacat
     3301 cgatcccttc aaataagtgt aatgtgtgtg gatttaatcc accagttaca gaaacattaa
     3361 agcctagttc aatcagtttt ttgatcttcg ataaatcttt ttcaccccaa gtttcaccag
     3421 ataacagcgc atcacggctt tgatggtaga ttacctgccg gataccgatg ttatgccaat
     3481 ccatggcttg ttcaaaagtc caattgccgt agagttctac ttgcaattca cctatttctt
     3541 tttgtgctgc ctccatagtt ggaatcgttg cacaacaaat gactgtcatc cagtctgctc
     3601 ctgcttttgc aacattactc gccactgttc ctccagcgtc tgcacatttc gtatcagcga
     3661 ctagtttttt atctgggaac atactgcgaa tacagcgaat cgctttttgt ccttcctgta
     3721 agcaaagaat tgtgcccact tcaataatat ctactacatc accaactttc ataacatctc
     3781 ctaatgcatg ttctaagtca ttgtgatcta acgcaatttg caaattcggc ctgctcatct
     3841 tagttccttc ctttacttgt ttttttggta ccactttgtt tcagcaaatt tttcactgat
     3901 ttctttgact gacatcacat ttttgatacc gataactgta actccttttt tctctgcctg
     3961 agtaaacata ttcaaaaaat tgactggcgt aaaaactaca tcgtattggc cagctgaact
     4021 ttttccctct gaaatggcac aatgatggat tttggtaatt ggtacgttta gttctttcat
     4081 tgctttttcc acacttctca tcatcatcaa gcttgttcct gatccatttg cacacgatac
     4141 taaaattctc atcttaatcc ctccattatg agtgttgtct aatcagattt tcttttatac
     4201 tctctgcttt tctgcatatg tgtcatagtc ttctacaatc aaaaaataac catcaggatt
     4261 tttccgatat tgtaactgcg gaatagccaa taaaccaatg acaactacgg caattccagc
     4321 ataacctagg actttcatga ttactgtaaa caatggccaa gctgttgccc agtcgaacat
     4381 cccgatataa ccaccgtatg ttgacatccc aatccatgta gcgaataatg ctgaaccgcc
     4441 tacttgtatg attcctgaaa gaaacgggaa caggcaagcg gctttgaatc cacctcggtt
     4501 attggcataa actgctataa cggcattatc aaagaacaac ggaatgaaac cggctatgac
     4561 gatcgttggt gatttcaata aaatcagtaa accaatcatc aaaaactgtc ccaaagcacc
     4621 aaacaagaac ccaatcgtta ccgcatttgg cgaaccaaag ccaaaagtag cagctacgtc
     4681 aattcctgga acagctcctg gtaaaatcgt gtttgagatt ccttggaaag attgagttag
     4741 ttcatcgacg aatgtccgaa cacctaattg caagatcgcc agatataccg caaaatttaa
     4801 agaagtcgtc ataatgtaga ataagaaact ctgcccttct tgcatgaatt gcgcttgaat
     4861 caaataatct ttgcctagta caatcagaat gatcccaaag aaaaatagca tgagtaacga
     4921 agtagcaacc atattctcat tgaaaatcga caagaatcct ggtaatttga tatcttcaat
     4981 ttttttgtct tgcttgattg atctattttt cttttcatcc cgctttttca tccactcagc
     5041 taattttgca aatataaaga ttccgaacat ttgctgatgt gccactgcaa atccggcacc
     5101 ttctgtcaat tcctgcgtga ttcctactgt taagttagaa gctactgtcc aataacaacc
     5161 taaaatcagt cccataaaaa tcaatgcttg tatcctacct agatcaggaa agcaaaacag
     5221 taaaatccaa aaagcggtag ctgcttgttg aacctgaacg tttccggtag tgaaaacgga
     5281 acgcagtttc gtatatttct gaaaacggac taataagata tttaaaacaa atgcaatcag
     5341 taataaaatc atcacatctc caaaggtacg gccaaatgtc tccattaatc cagcatccac
     5401 agcattttgt ccaaaataag gatctgtaac catggcatcc aaattgaacc gttcctttag
     5461 tccaaccaag attggccgaa aattattgac caaaccacca gagccaacag tcaaaataaa
     5521 gtaaccgacc gttgccttta agaatccagc gatgcattca tgaagcgggc gtttcagcaa
     5581 aatatagcct aataacacga taaaaccaat caggtatgct ggctgcgtca agatatttgt
     5641 tgcaaaatac gtccaaatgc ttaacaaaaa ttcccccatc ttttttctcc tctatcaatt
     5701 aattatattc tgccatcaca acttggtaat catcgatgga gttcgtagag atgagacgct
     5761 caaccaatcc atctgtcatt aataattcgg ataatttttg gatattttct agatgttctt
     5821 ctggatcttt tgctgcgagt gtaaaaaaca aactagccgt tttctcctca ttctcccctt
     5881 cactttcaaa acggattggc tgtttcaact tggtaaatga aatagctgtt ccaaaaacac
     5941 catcactttt ttctgaagaa tgcggcattg ctacttgagg tgcgatcaca atataaggac
     6001 cgtatttttc tacacaatgg atgatctcct ccacatacgt ttcatcaata atttccttat
     6061 cgatcaatac aagacagctt tcggcgatag cttcacgcca atccgtgatt tctttatctg
     6121 ggtaatgaat caattgatgg tcaaaaaagt atttcagcaa gaaactcccc ttctttctta
     6181 taaaaacgac ggaaacggtg tatcattttc aatcgagaag acatcttcaa atcctcgata
     6241 aaaattaaac tcaagatcat ctttgtttgt cggatagatg aatttcccgc ctacttgcca
     6301 gatataaggt ttaaatccat acttcaggcg atcctttttg aatttccaaa tttcagtgat
     6361 ctcttttgga tcagccataa aattagacca aatatcgtag tggacaggaa tcactacttt
     6421 tgcattcaat gactccgcca tgcgcagcat atcaacagaa gtaactttgt ctgttatccc
     6481 tcgtgggttt tcaccatagg cccctaaaca gacatcgatt ttgtgttcat taccatgttt
     6541 ggcaaataaa ttggagtaat gtgaatctcc tgcatgataa agattccctc ctgatgtttc
     6601 gaataaatag tttactgcaa tttgatccat ctcctgaggc atttttcctt ttaatacctc
     6661 ttctggatct tcacaagtga ccaacgctgt ccgatcaaac gcttctaaag ctactacatt
     6721 gatgtctttg attttgactg catcacctgg ctttactgta atcgtttttt cttcaggaat
     6781 tccccatttt tgccacgtgc gaaccacttc ttttggccca atgaatgttg cttcaggaca
     6841 attttgatga actgctgcgg ctgtatggat atctagatga tcggaatgga tatgtgtaac
     6901 gattaaagcg tctacatttt ttatcgcaaa aggatcgatt acgaaaggct gagtacgtaa
     6961 attaggctgc atattttgaa cgccactcat acgcatcatc tgatggcctt ttttcatcat
     7021 gccattccca tgactacgtt ttcccgtccc acaccataga tcacataaaa tattcgttcc
     7081 ttcatgactt ttcagccaaa ttcccgtaca gcccagccac cacatagcaa aagttccagg
     7141 atccactact tctgtttcga tttcttcatt caagtatgtg ccccactcag gaaatgtttc
     7201 tactaaccac ttttcttttg ttacttcatt gacagtttta ctcatttgct tgctcccccc
     7261 atatcgttgt tccaacttac aagtaaatat taatgtgtat cagcatccat gaaaaccctt
     7321 ttatatgacc gtttgttttt tatatgattt tctttcagta atcaatgatt gtttcagtat
     7381 aataaagaca gatatgaatg tttaaatgaa caactagtca aataaatcca tggatcaaga
     7441 tgtccctcag gaggcaaaag tcatgaaaaa ctcacttgtc aatattgaaa aacgtcaaaa
     7501 agaaattttg gaactgcttc agcagactga acaactatca actttcgaat tagctgaatc
     7561 ccttgatgta tctattagta cgatacgaag agatttaaat ttattagaag aaaaaaacga
     7621 gatcatacgc aattacggtt attgttctta taattacaaa aaccagactg attttgatca
     7681 atctggtcct gaaaggatta aacaagcgat tgccagagaa gctagtaaat acattaacga
     7741 ttatgatacg ctgtttatca attctagctc gactgcgttg aaaacactgg attttcttca
     7801 atctaaccat ttgacagtca ttacaaacaa cgtgaaaatc aattactctc cgcacaaaga
     7861 taattgtagt tatattttaa ctggtggaga gatgcgcttt ccaaaagaag cactagtggg
     7921 cgacatcgca ttaaatacga tttcttcagt caatgcagac atttgtatca ttggctgtag
     7981 cggagtcgat gtagtacatg gggtcacaac aaagatatta aatgaatcaa cgatcaacga
     8041 aatgatggtc aacaagacaa tcaaatgtaa gattttagtc gctgatcatc gaaaaatcgg
     8101 actgacatca aagttcaaga ttgctgatat ttcagtcttt gattatttga tcactgataa
     8161 attttgttct gaaaaagtat tagaggagat cagaaatacg gggataaaaa ccattcaagt
     8221 agattcattt taagaaccag gacgtaaata tgtaaatagg attatcaaaa aaatgaataa
     8281 caaatttatc gataaatgaa aaacacgcta cgctcaaatt gataaaggaa tcccaagatg
     8341 tatccatcca atcgatacca tcataatcta ttgcttcttt tataaccgtt atatgttgcc
     8401 taaataggaa tcaaacaata tcgaaaaaag gaggtatgac aaaagtcaca cctccttttt
     8461 tcgaataaac ggtattcaaa tcagaacact gatttcacaa ccactttatt tcaggtcgtt
     8521 ttcaatcacc tttaccgcgt aatcatttcc gttgaaacgc gctatttttt ttgcgtccat
     8581 atatctttct aaataatcat cttctcctaa ttgcttatgg caagaagcaa tttcataaag
     8641 caagtattcc aatgcataag tcgatttatg tttcttatta tactcaatac ccttctcaca
     8701 taattggatt gctttatcat aatcctcgat tttacggtaa taggtggcga tatcataata
     8761 tacaatgcag accatcagat tatcaaaatc agtctcactc aatattttaa gtgtacgctc
     8821 cacataaact ttcgcaaaat ctaattctcc ttttgacaag tagatcattg ccacgtttgc
     8881 agctgcttgt aagtgatgga tatctgtttc ggtcgtttgt tccaacactt gattaaaata
     8941 aaataatgct gcatctggtt ttttcgcata aagatgatca agcagtcctt gataaaataa
     9001 aatttgattt aaaagatcag aattacttac tttttcctga tcgatcgttt gtaaaatttt
     9061 ataagattct tggtattttg atacagaatt caatgattga atctcattta tttttttcct
     9121 gattttgtct tcttctgttt ctactaatat atcggagatc tcgacattca gctttttgca
     9181 aagcgcactt aagatattga tgcctggcga catattcttg ttttcgatat tgctgacagt
     9241 tgcttgttca caaatgcctt ctgctaattg tacttgtgtt aacccctttt tctttcggta
     9301 ttcttttagt aatgctccat ctactttaat caaaacaatt tccttccctt taaaaaatta
     9361 tttctccttt atatcataca caaaaaaaag ttctaaacaa ccaaaaatgt ttagaacaga
     9421 ataaaaattt taattttaaa ataatattca aattaaacaa ctggcgtatc tgctccttga
     9481 tttctttttg tgttatctga ataattatcg tttacagtta taacacatag tgaaaattgt
     9541 catggcgaga aagtctaaga atatttttaa acataactat ttctttctta cgtgtgtata
     9601 atgacgacag cacacctatc aattaatata attattttat ttttttatgt tctcatgttt
     9661 atttttaatg acacaacttc tcgtatttat ctggcacaac atataaatcg atcaaaaaat
     9721 tgttgcgtgt ttttttgaaa attggagttt caacttgatt acaaaattta aatttagaag
     9781 ttgtgaaaac agcgagagac agtttaatat tcaaaatata cataggctac tcgaacgctg
     9841 tgttttttag tatactagta agaaacgaag ggatagactc attccaataa ggaggatttc
     9901 atgaagacaa ttctttttgc tcctgcagta ttcaatttag ctgagacaac acgaatgatt
     9961 gaggttgcca aagctatgaa agaccgttat tactgtgtat tctttggctt ttctaaaact
    10021 tttgctcctt tgatcacaga aagtggcttt gagtatcatt tactagcgcc gatccttacg
    10081 aaaaaacaag aagaacaaat cataaaattt gaccagttgc gtacacttaa aaaccctttt
    10141 accaaagaaa tggttgcctc tcgtatcact agtgaacaga gtctgattgc taagtttgag
    10201 cctcgactga ttgtgacagg ttcgaatgtg acaatttttt tatcggcccg caataaaaag
    10261 attcctttag tatatgttaa accctatgct ttgagtgaac ctttttttca atcagagcat
    10321 gcgctgatgc cccacgagtt acgtttcttc ggccctttaa gcaatcccct ttggcactgg
    10381 acaaaaaagc gtatagtaaa tacccgatgg atccccaatg ccttcaaaca cgctgcacaa
    10441 aaagaaatgc ttcctttacc aaaaacaagt ttacaaatga tggatgctga tctaaatctc
    10501 atcacaacgc ctaaactatt tttggaagaa gaacagctgc cggaaaatta tcgaatcgtt
    10561 ggtccaattt ttgctaagct cagtacttcc ttgcctgaag aagtgctaac ttttatacag
    10621 cgaaagcaac aagaaagaaa acgtattatc tatttcgcaa tgggtagttc aggcaatccg
    10681 cgtatgttac gcaaaatttt gttcttctta caaaaacaac cggatctagc ggttattgca
    10741 cctattgact atctgcttga tgacattcaa tctgactcag aagatctttt aataacagaa
    10801 tatctgtcta gtcatctttt gcatgaattc attgattttt cttttatcca cggcggggaa
    10861 gggaccgtcc aaactgcctg tgaatccggc aaaccgttta tcggtgtggg gatgcaattt
    10921 gagcaaagct gtaatattga ctattgtgta aaatacggaa acgcaatcgc cctcacaaaa
    10981 ccagtgactg aaagaaaact gcagattgct ctgcgcgaag tttcttcacc caagattcgt
    11041 cagcaggcac gcacgctgca agccgttttt ccaataaatg gtccacaaca agcaattcaa
    11101 gaaatcgaaa ccttcctgag caaccaccca atatagtttc aagtagaaaa agctttttta
    11161 atagagactc atcagtaatt tcgctattcg agacccagac agtgaaaata caaaaaaagt
    11221 aaatagtgga ttgaaaagtt agagttactt aaattacggt gtctaaaaaa cacaaaatca
    11281 tccttaaaat aaaagatctg acgctatcca aatgagcata ggtagcgtct gccatttatt
    11341 cttagtcaaa ttctttgaca cctttctctg gttggatcat ctcaacgttt cttcaaaaga
    11401 aagaccataa taattaggca aatacatttt cttaaaatgt gtcatataga tctagaagca
    11461 tcgctttgta gagatttgtg ccgctagtcc cctcaacaat tactaaatca aatgtaggat
    11521 ttaccacttt atctttgata atcaacctcc ctcttctgtt gagacaatga tctcgcaatc
    11581 cgatgcatac tcctatataa actgccagca atccccacat attgagtaga tcatgtcaga
    11641 atgttctatg tcgtcagcaa cgatacacta aaagtcacgt tcaccatgac tgattgctat
    11701 tcccagcaca attatttcta tacacgtttc atgatttgaa taaacactca catcatacat
    11761 attaccattc atacaccata ctgcagcccc tactatatgg ttgtaagctc ccaaatctat
    11821 atttgacttg atcactttgg tagtagatct actaattcta aatccattgc tgataaaatt
    11881 tccatttttt cctccttctt tctgccaaaa cagttaaaac aataataatc tttatgtaaa
    11941 aaagggctgt gacaaaagcc ttgtcacagt cccatattcc gaataaacgg tggtcaaaag
    12001 cttgcatctg cggtaataag ttcaaccaaa cgaaaaataa gccaacattt cacaaaaatt
    12061 taagaagcaa ttttcgtaaa tttcttctta tttcttgaag ctaaccactt ctgttacaac
    12121 cacttttaga acatttaaag cttcgatgtg acaaaccatc tatgctgctc gatcataaaa
    12181 ttgatagcaa aaattccaca aagtacatat gtcccccatg aaaacaaaac attcatatgc
    12241 ggtacaatga tctttggaag aatcacgatc aaaaatgatg ccagtgccca aatccatcga
    12301 ttgatttgaa tatgatatgt agctagcata ttcaatataa ggtgactagc cgttaataaa
    12361 aagataaaaa caaaaaataa aatcagccaa tacattgttt cccaccttct aaaaaccaaa
    12421 cttagacagt ctggacttcg ttttctccac gactttgttc atctgacagc atctttttat
    12481 cataagcttt tacaaatgga taatagataa taaatgctat caatgtgttg atcatgatca
    12541 agataacaac acgccagtca tttcctgctg aaagataacc gccgattgga gctggtaatg
    12601 tccatgttgg caaaacagta aatctattga ccatttctaa tttgactgca aaataactga
    12661 taatagtcaa aactaaagga actaagttga acgggatgaa catgtaagga ttcaacatca
    12721 taggagctcc aaaaattatg ggctcattga tattgaagat accaggaata atagaaaaac
    12781 gaccaacctc tttcaagaat tttgatttac agaagaatat aaacaaaaca gataccacga
    12841 tcgttgctcc tgcaccacca attgttaccg tccattgata aaactgttca ggagcgatat
    12901 agggtaattg ggtggcagct gtaccatctg ccaatgcctt tgcattctca tccaacatga
    12961 tcagccacat tggacgaaca acagccccta caatactcat gccatggata ccaaatgacc
    13021 acaacaaatg gatcaaaaac attggtagta aaacaccaag caaattattc cctaaaatat
    13081 tggttaaagg ctcgaataac gataataagg cagcgtttac atcaaagccc gcgacgcttc
    13141 gaatcagcca agtaattgtt aaaatgactg cacctggaat caatgcctca aaactacggg
    13201 caacagcagg tggcacttgt tctggcattt tgatagtaat atttcgattt ttaaagaaac
    13261 gatatacttc cactgcaaaa atcatagata agatccccgc aaacatccca gatgctccca
    13321 aagaactcat aggtaagacc cagccaagag gtgcctcttc aggagttaaa acgtttacag
    13381 gaacttgtaa cataaagaac gttcctaaag ataatatacc acctgtcaca ctatctaatc
    13441 catatgattt agctagatcc gaacccataa caaaagttgc ataaatagcc atcaatccca
    13501 tcgtcatcct aaagggtaaa acaatcgttg ccgaataagg ggcaataaat tcattccatc
    13561 caggaaacgg taaattgata aagaccataa aaaatgtccc aatcaaaatc aatgacaatg
    13621 ttgaaacaac cccattacga attgctaata aatgacgctg tgtaccaatt tttgccattg
    13681 gtgggacaag tttctcttcg acccatttca tcagcttttc cactaaaacc actccttttc
    13741 aataaaatat gaaccattca ttgcatgaca acgcaaagaa tgttcataac taattatata
    13801 attaagaaat tttatttcaa tatattctct taaataatca aatttatttt taagaatcct
    13861 gaaaataagt tttctaaatc ataggagcaa caaaaaaatt cgataattaa caaaaatcaa
    13921 aatgattaaa tctagtgatt gaaacatatc atttcaaaaa aattttgtaa attcacccat
    13981 aaatatcacc ctatttaact tttttcatcg tacactaaaa ttcaaaacaa ctatctttaa
    14041 tctttacttc ttggttttgt tttaataaat ttccttcaaa aatgcctgga gaaactacaa
    14101 tgatcaccgt atctttttgt gcttgctcca acttcttcaa atctataata gctaacagtg
    14161 tcccttcttt tacctcctgg ttactttcaa cccgtatctg aaacggactt ccttcgagtt
    14221 caactgtatc taaacccata tggatcagta tttttctgcc agattcactt tcgatcgtta
    14281 tggcatgtcg ggtaggaaat atattatcga ttattccttt aactggcgca tggatatatc
    14341 catcatgatt cgttatagcg tatccaactc ctatcatttt tgaagaaaag acctcgtctt
    14401 ttactgctgt taatggaata atttgaccac tagctacagc ttttagaatg tttcttgttt
    14461 taaagaaatg cactttttat cacctctact ttaatgctgg ccaatatttt ttgtttactt
    14521 tgatcatttc atctagtatt ttttttgcga ctctggcatt tggtacggtt tgattcaatg
    14581 taaatgcttg taaagctttt tgataagaac cttcaaagta agcatctact agtaacttct
    14641 ctactgcaac ttgtgcctcc atcaatcctt tatgaaaatc actgattggt tttcttagtg
    14701 taattggctc cacaccagtt gcaccaacat atgccggtat ttcaacaact gcatctgacc
    14761 gtagattcgg aatcgcccct tgattaggaa cgattagcat aaagcgacga cgatcatcat
    14821 tcaacaagga aatagctata tcgacgatat attgtccatg ctccccaaaa ttaaagttca
    14881 atacttcttc cacaataccg cggcgtattt tatcagccat ttctttggta tttttctctc
    14941 gtccatccat gaccatatta gcacgtgtat actctttgtc agtatgctca acgaccatat
    15001 caggatataa gtaatactct aagtaattat tcgggatatt acttggaaaa tttttcgtga
    15061 tgactgacat catttgaaag gttttttgcc aagttttatc tcctatatta aaatcggcga
    15121 cttgcatttc ttttgttatt agtttttcaa taatctctgg cataatttct cgttgcaatt
    15181 ctttatcata aatcgatgta taccagccaa agtggtttaa accataatac gtaacgatcc
    15241 aattcttacg atcataaccg taattcactg caatcgtttc ttcaattgaa atagtcatat
    15301 cacaggcatt aatcattttt acattcggat atttacgacg aacagcttca gaaacgatcg
    15361 actctggatt tgtataattc aaaatccatg ctttgggggc atagtcttgt atatgatcga
    15421 caatttccaa taaacctttg attgagcgca tcccataagc aaatcctccg agtccacacg
    15481 tttcttgtcc tactaatcca tgtttaagtg gaatcttttc gtccttttct cgcatctcca
    15541 atcctccaac acgaatttgt gagaaaacaa aatcgcatcc tgtaaaagca agctttggat
    15601 catccgttgc acgaatgcga atatttgaaa aaccttttct tttcagcata aatttaacaa
    15661 tcaagtacat atccatattt ctttcttcat caatatcata taaacgtatt tcagataatg
    15721 gcaaccgttt ttcattgttc aaaatggctt gaacgattcc tggtgtatac gtactcccgc
    15781 ctccagctat agtgataatc tgttttttca tcatcatctt ttcctttcta ttcttctaat
    15841 aatttattga attctgccat aacataagtc acttctaagc cgatgataat ttgataattt
    15901 ttttcagttg gtttaatgat cccgcttatc cctaattgct tgattcgctg ttcctcgacc
    15961 atggtgggat ccactacctc tacccgtagg cgtgtattac aactatagac atccaggata
    16021 ttggcttttc ctccaaacgc ttgtagcatt tttgttgcca tatattcata atttttactt
    16081 gctaacccta actctgtttc ttctaaggtt acttcattgc caaactctgc cttagcttca
    16141 cgtcctaatg tctgaatgtt tctcttattg atcaaataat aaaaagtaac gtaatacaag
    16201 gcaaaaaaga aaattccgat tggaagaatc aaaatagcat tggtagcgat tcgaaaattg
    16261 atgagataat caacaataca tgctccgaat gtaaaaccaa ttcgtatatt gaataagtaa
    16321 cagacaatcc ctgctaaacc ggcaaaaagt gcatggatca cgtacaacat aggagaaaga
    16381 aacatgaaac taaattcaac aggctcagtg atatttgcaa taaatgaagt tcctgcaccg
    16441 cttcccatga ttcctttgac catctcttta ttttctttat aagctgcttt atagatagct
    16501 agacatatag ctggtatacc aaacatcatt actacaaaaa aaactgataa aaacagtcca
    16561 gcctgaggat ctccgttgat aaagcgtgtc atctctcctc tgaaaacttc cttgctagga
    16621 gatgtatagc ttcctaaatc gtaataaata tacgtattca acacatggtg cagtccaaag
    16681 gggatcagca aacgattcaa aaacataaat atccccacac ctaatgctcc catatcaacg
    16741 agcagttttg caaaattatc aatcccaatt tggatgagcg gccagataaa gcccaaaaaa
    16801 acagctgcga ttgtttgtag aatcatcacc atagtcaatg ggaatttttc gcccgcaaaa
    16861 taagaaaaaa ctactggtaa tttttgttct ttaaagcgat tatacgtcca tgccgctact
    16921 aaaccggaaa taattccacc aaaaatcccc atattcactt ctgggtccat aatttctaag
    16981 ccttttttca aggtagcaat cgctaaaaaa ccagtaagtg caggtattcc tttgtcctta
    17041 tttttgacaa aaccgattgc aactcctata gcaaataaga tatccaagtt tccaaaaacg
    17101 gcatttccag ctgcaccaat tactgggatg ttcagcatat cgtcagctga taaacgcatg
    17161 atcaatcccg ctaatggcat cgctgcaact ggaagtagca tcgctcttcc aagcttctgc
    17221 acatttgatt taacattcat ttttattcct cctctattaa atatcctcat atgttactaa
    17281 ctcaatcaaa ggatcatttt tcactttttg agcaaatgct gaatgaatta aaaattcgac
    17341 ttggtgggta cgaggataca caaaacttga accatttaac aattcctgat ccaaatacgc
    17401 tgcgtgacac atgacttcga tcgttttatc ttctctcaat atcatgagta aacttgccaa
    17461 atattcttcc acactcgtat tgatttgtcg ttttttttca tcagtttctc ctacgacatc
    17521 gaaacaaggc tcaaaataat cgacatgacg aacttcatct tttcgttcaa agttgctccg
    17581 aaccggcaaa tcatattttt ttgctaatgt aacaactacc tcctgatttt catccaaagt
    17641 atgagtatga tgatgactgt ctaaatgagt tggtatgatc cccgcatgat aaattttttg
    17701 aatctgagca ttccattcct gatacagttg atctttgtca atgttaaatg gatgctgata
    17761 ataagataag gatctgaact ctccgctttc gataagagta tcgacagttt tgaggagtgg
    17821 tttgccacac gtcaatgtta aatggactcc tacacctagc ctaggcattt cctttcttag
    17881 tttcacagca tgctcgaaac ccggcatatt tgccatcaat gtagttgatg tcaaaattcc
    17941 tcgctgataa gcatccataa tcccataatt cacaccatgg ctatagccaa aatcatccga
    18001 attaaaaatc acttttccca tttcattctc cttctttttt ctactaaaat aggcgcaacc
    18061 aaataatcat agtccattta ctatgtgtca tttggttgcg cctatagata gttacgccct
    18121 tattttaata gattcttgct agatgaattg ccaaatagat gatttcattt tcttgaatgg
    18181 caagttgaaa ttgctgttcg atgatatctt taatctttag tgctgtacaa tacgctttgc
    18241 tatgtttaaa tgtttcagta aaaaaaccaa tattttctac tggcgtttct tcctgataaa
    18301 tcaagcgttt aaccaggaat ttgatatgaa ccattaagcg atgataagtc agtgattctt
    18361 tatcataaac gtttgaatag gatttttcta gatgggacaa aatcgtggtc gtcatttcta
    18421 ctatttttaa gctctttaaa ctattaggct ctcctagctc agcattaatg atatgcatag
    18481 tgatgaatcc tacttcattt gaccctaact cggtttgata tcgatgattg attcgctcga
    18541 ccacttctac tgctatatca tattcatttg gataaaggaa tctcatttct ggcaacataa
    18601 ttgctgtgac atctctatct tctctttttc gttgaatagc aaaataaata tgatctgtca
    18661 atgtaatata gatatttgaa tctaatggag aggagatcct agctgttatc agttcaatca
    18721 cttcttccgc aaaatccata aattcgattg gaatctgcga gactatctca ctgaatcgtt
    18781 tgatcttttc tttagaatct aatacaaata atttgtcagc atcctcaaca tcaaatggct
    18841 tactcacttt agcagaaaag ccaatccctt tccccatcgc aattttttct attccatcgt
    18901 catcgatcaa tacagcatta tgattcagct ttttcatcac atacaccgtt aattcacctc
    18961 ctctatatga taaaacaaaa caacttgcag actccttcat acatattttt gtctccaaac
    19021 aatttttaaa gacaaaaaac gacctaagaa agaacccttt cttaggtcgt gcctaattga
    19081 atagtagcac cctacataat ttacaaaaat agtttaacac ataataaaag cgttatcaat
    19141 atctttttta ctcgttttat gataatactt gtatcgaatt gatttggagg taattacata
    19201 aaaacaaaaa aaatatagca actctctata agaaagttgc tatattgata attataccgg
    19261 cggccggggt cgaaccggca cgtcctcaac ggacactgga ttttgagtcc agcgcgtctg
    19321 ccaattccgc cacgccggca aatttaaaaa taataactgg ggtagctgga ttcgaaccaa
    19381 cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct ataccccaag aataaagggc
    19441 gaatgatggg aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt aaccacttcg
    19501 ccacattcgc catcataaaa gatgttattt aatttctcaa taaaaaacta agatgaagac
    19561 atcttagtca ataccggcgg ccggggtcga accggcacgc cctcaacggg cactggattt
    19621 tgagtccagc gcgtctgcca attccgccac gccggcaagt tgatttatta gtactaaggc
    19681 ggtaaccgga tttgaaccgg tgatgaaggt tttgcagacc tctgccttac cacttggcta
    19741 taccgccatt atactattat caatctataa aataaagaat aaattataga aactggggta
    19801 gctggattcg aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac
    19861 cccaagaata aaaagggcga atgatgggaa tcgaacccac gaatgccgga gccacaatcc
    19921 ggtgcgttaa ccacttcgcc acattcgcca tggcaggggc agcaggaatt gaacccacac
    19981 taacggtttt ggagaccgct gttctacctt taaactatgc ccctataaaa tggaggagag
    20041 tggattcgaa ccactgaacc ctaaggaacg gatttacagt ccgtcgcgtt tagccacttc
    20101 gctactcctc catggtggcg cgggacagaa tcgaactgcc gacacacgga gcttcaatcc
    20161 gttgctctac caactgagct accgcgccat attttaaaat tattaattga ataacaagaa
    20221 cgacggttcc gacgggaatc gaacccgcga tctcctgcgt gacaggcagg catgttaacc
    20281 cctacaccac ggaaccagtt cattatggag gttaacggga tcgaaccgct gaccctctgc
    20341 ttgtaaggca gatgctctcc cagctgagct aaacctccaa cattcaatta aaatgacccg
    20401 tacgggattc gaacccgtgt taccgccgtg aaagggcggt gtcttaaccg cttgaccaac
    20461 gggccaggta aatttgctac ggagagtaag ggattcgaac ccttgagaca gtttggcacc
    20521 atctacatga tttccaatca tgctccttcg gcctctcgga caactctcca gagtgaaaga
    20581 agctcaatac tctttctcaa aatgagaact ccggcagtag gactcgaacc tacgacatca
    20641 tgattaacag tcatgcgcta ctaccaactg agctatgccg gaataacat
//
LOCUS       DACCVH010000050        19635 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.050, whole genome shotgun sequence.
ACCESSION   DACCVH010000050 DACCVH010000000
VERSION     DACCVH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.050"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="IVV98_001847"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="IVV98_001847"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP7807486.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="IVV98_001848"
     CDS             complement(1174..1869)
                     /locus_tag="IVV98_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP7807487.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="IVV98_001849"
     CDS             complement(1882..2598)
                     /locus_tag="IVV98_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP7807488.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3536
                     /locus_tag="IVV98_001850"
     CDS             2928..3536
                     /locus_tag="IVV98_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP7807489.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3861..4184
                     /locus_tag="IVV98_001851"
     CDS             3861..4184
                     /locus_tag="IVV98_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP7807490.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4366..5736
                     /locus_tag="IVV98_001852"
     CDS             4366..5736
                     /locus_tag="IVV98_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP7807491.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5866..7167)
                     /locus_tag="IVV98_001853"
     CDS             complement(5866..7167)
                     /locus_tag="IVV98_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP7807492.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7521..9512)
                     /locus_tag="IVV98_001854"
     CDS             complement(7521..9512)
                     /locus_tag="IVV98_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP7807493.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9656..9922)
                     /locus_tag="IVV98_001855"
     CDS             complement(9656..9922)
                     /locus_tag="IVV98_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7807494.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10432..12558)
                     /gene="pnp"
                     /locus_tag="IVV98_001856"
     CDS             complement(10432..12558)
                     /gene="pnp"
                     /locus_tag="IVV98_001856"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP7807495.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12746..13015)
                     /gene="rpsO"
                     /locus_tag="IVV98_001857"
     CDS             complement(12746..13015)
                     /gene="rpsO"
                     /locus_tag="IVV98_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP7807496.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13266..13829
                     /locus_tag="IVV98_001858"
     CDS             13266..13829
                     /locus_tag="IVV98_001858"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP7807497.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14082..14603)
                     /locus_tag="IVV98_001859"
     CDS             complement(14082..14603)
                     /locus_tag="IVV98_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP7807498.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14606..15448)
                     /locus_tag="IVV98_001860"
     CDS             complement(14606..15448)
                     /locus_tag="IVV98_001860"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP7807499.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15441..16166)
                     /locus_tag="IVV98_001861"
     CDS             complement(15441..16166)
                     /locus_tag="IVV98_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP7807500.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16342..16638
                     /locus_tag="IVV98_001862"
     CDS             16342..16638
                     /locus_tag="IVV98_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807501.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17206..18798
                     /locus_tag="IVV98_001863"
     CDS             17206..18798
                     /locus_tag="IVV98_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7807502.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18811..19551
                     /locus_tag="IVV98_001864"
     CDS             18811..19551
                     /locus_tag="IVV98_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7807503.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5621 a         4028 c         3724 g         6262 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcaaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aagaaagcac aggtgaaggt ggcgaaccag aagtgatcgg ttcaacagaa gaataatact
     3541 gaaacaatca ggtggtgtta gaagcggcgg gtcagcagct tttaacacgc cttttttatt
     3601 tctaatcgtt tattttcata tggggcttcc acttttgtaa atggctttac aaacgaaaaa
     3661 tcctaattta ccaagctttt cctcgcatac ttttatcgta cctttataaa aatttatact
     3721 ttgaaaaaaa gtattcaatt attgttgcat ttttcctgat tctttattag aatgaaccct
     3781 cgttgaagta agtatttcta gtttatccta ggattaatta taaaaataaa acattcgttg
     3841 attcgaagga ggttaaacag atgtttgaaa gttttgatag cagccgcaac cgttacgctt
     3901 cagttggtgt cgtatcaagt ttgccagatg aattgattga cagtatatgg tttattattg
     3961 acctagatct taagggagtc attccattag aaaatatatt aacctttgat ttgatcgaaa
     4021 atcgtggaaa agtgacgatg catttttctc aagcaggaag caatgtggaa atggatattg
     4081 atttgccgtt tgcctattcg aaccaatttc ctgctcaagt atacgcctat gatgacggta
     4141 cgagagaaac gatcctttta ccaagtgaga ttagacaata ttaaggtgat agataaacgt
     4201 ggatgtccct tattttacag accaggccaa gttgttgatt ctttgactca attcttggct
     4261 tctttttatg gagtttcata aattatcatt gatttctaat tggtattctc aggataaacg
     4321 ctatatacta ctaactaaat tttaaagata taaggagttt aaaagatgcg cgatttaaca
     4381 aaaggaagcc ccgctaaact gattttgatg ttcactgttc ctttactgat cggaaatgtt
     4441 tttcagcagt tctacaatat gatcgatatg atcatcgtgg gtcagacgct aggtaaaaat
     4501 gcgctggcag cggttggtgc aactggaagc ctgacatttt tgatcattgg ctttgcccaa
     4561 ggtttaacag ctggtttagc cattattacc gcacaacgtt acggtgcaaa agattatcgg
     4621 ggtctgaaga aaagttttgc tgctagtgtt gtcattagtc ttgtcgtcac tgtgatttta
     4681 actgtcctaa gtctcctgtt tattcgtccg atgcttcaat tgatgcaaac tcctcctgaa
     4741 atacttgatc aagcacaaac atttatttca attattttat tagggatctt tgcatcagtc
     4801 agtttcaatt tgctttctaa tgtcattcgc gcacttggtg acagccgcac accactattc
     4861 tttctgatca ttgcggtcat catcaacgtc gtacttgatt tgatctttat tatctatttt
     4921 ggcatgggtg tggaaggtgc agctattgct acagtaatcg cacaagtttc ttccagcgta
     4981 ctgtgtctag tgtatatcaa gaaaaaaatg cctttgttac agttacgcaa aaaagatttc
     5041 aaatttgaaa aagaagagtt tgctgtacac ctaaatgctg ctttgccaat ggcgtttcaa
     5101 tcttcgatca tcgctgttgg tgctatcgtg ttacaagcag cactaaatag tctagggaca
     5161 gatgtcgtag ctgctcaagc cgctgctggt cgtatcgacc aatttgcaaa tcagccgatg
     5221 atgtcatttg gtattgcaat ggcaactttc actgcacaaa actatggtgc gaaagaatat
     5281 ggccgaatct tgcaaggggt acgtcaaact ttactgatga gtgtcggatt tagtctctta
     5341 gcaggtgcta tcgtcatttt cttcggtcat ttctttgttc aattgtttgt tagcccatca
     5401 gaaacacgtg tatttgaatt agcacaaacc tacttcaata tcaatgggtc tctttactgg
     5461 atcttagcag tcctgttcat tttacgctac acacttcaag ggcttggaca aagcaagatc
     5521 cctacgatcg ccggtatgat ggaattgctt atgcgttctt ttgcagctat cgttcttaca
     5581 ggaatgtggg gatacccagg agcagcagca gcttctcctt tagcttggat cggttctgtt
     5641 gccgtgttgc tttactctta tatgcgttcg atgaaacaat tgaaacacat gggtgaagag
     5701 gaacatttca cattagaaca tgcagaagca agatagcctt gattaaaaga aatcgttgcg
     5761 gctaaaaatg aaaactttta ttgaaaatat cttcttcgtt taccgaaaac aggtttttta
     5821 gataacaaaa aggctgtgac aaaaaatgtc acagcctttt ttcttttatt ctgtttttct
     5881 ttccgtggac tctactttga aataatcgat atgtgcatgc tggtattcta ataccgtgaa
     5941 acggaatgat gcaatctcaa tgattgttcc tgcttttatt tctttatatc ggctagaagc
     6001 aaagcccgca agtgtagtaa aattcgtttc ttcaaactct ggaatctcta catgaaaata
     6061 acgctggaaa tcatctaatg ttagtttgcc ggagatgata taagagccat ctgactgttc
     6121 cgctatcaat gcttcgtcca aatctgtctc atctcggatt tccccgacga tttcttctaa
     6181 aatatcttca atcgtcacta agccgcttgt ccctccgtat tcatctttta agatagcaat
     6241 atgcttaccc ttttttcgca tgatcgtcaa taattttttt atagggatcg tttcagttgt
     6301 tacgatcggc tcttcaatca actgttctac tgtcagctgg tcatctttat aagattgctt
     6361 gatcaaatct ggcaaggtga cataacctaa aacattgtct tttgattcta agataaccgg
     6421 atagcgagta tgtccttgtt caatcgaagc ttttatcgct tctttgacgg tttctgaagc
     6481 ttcgaatact tgcatggacg tacggtctac ttgtatatct tttgccaagg tatcatcaaa
     6541 ttcaaacacg ttttccaaat aataatattc ttctttggtc aactctcctt tttcataaga
     6601 attcaatgcg actaatgtca gctcttcttg agacaatgtc tcttctcctt cagatacgag
     6661 acgcacacct aatagcttcc ctagccctgc agctgaatga ttcaataccc aaataaaagg
     6721 aaacattact ttataaaaat aatgaagtgg tttaactacg aacaagacga ccttctccgt
     6781 attgacgata ctatagctct taggaagcag ttcgccaata accacatcga tatacgtaac
     6841 taaaataaat cccagcgcca cagagattgt actgctaata gccgaactaa aaggtagttt
     6901 accgatcact ggttctagta aagccgcgac agatccttca ccgacccacc cgatgatcaa
     6961 accggttagc gtaattccta attgactagc tgataaatag ttatctaaat ggtgtgtaac
     7021 atgaagagct agcttggcgt tctttacatt ttccttttct agttgttcca atcttgatcg
     7081 tctgattttc actaaagcaa attcacttgc tacaaaaaat gaagtaattg caatcatcaa
     7141 aaataaaata atgaaattga taaccatatt ctcccgcctt tctctttttc tattgtaccc
     7201 tttttctaca aaaagattga aaataatgcg tattcatatt taggaataaa aaaggagatg
     7261 cggcattttt cagccacatc tccttatcac ttcaaaatca ttgcgttact tgttgctaaa
     7321 cagctttttc atgacctctg ataaaaacgg tattcaaaag cttgcatcta cggcattaag
     7381 cccaaacaga tgaaaaacat gagaagctgt ttttatctgc tcgttcttac tgcttgttgc
     7441 agtacagctt tttcatgacc tctgataaac ggtgttcaag tagctgacat tcgacattag
     7501 ttcaggtcaa agcgctactt tcacaaccgc tctttcaacc atgttttccg agtatttcca
     7561 atgataagcg gaacagtttc atgttttact tcgctgtact ctagcccaaa ccatgtttct
     7621 ggcgaggtag cgattttttt gattgccagt tttgcctgca tgatttgacg ttgccatttt
     7681 cctagagttg tcacattgga aactacttca tcaatcagga caaattggaa atcgccaact
     7741 tctcgccctg gtgtcagaga gtatctttgt ggctgttttg gcaaacggcc ttgtttcatc
     7801 aaatcatgga tgacttggcg aacatatacg ttgatttcct gttggaccct gaaacctaag
     7861 aacagattca cttggacaat aaaatcagtg tccatcatat ctacttgata ttctttcgta
     7921 tatggctcat ccgtcacttc cacatgaaca aaccaataga ctcgtgctct tttaggccgt
     7981 ttatctaaaa tcgaatagat gaactgtcgg ccaactttat cttcagccat atcaggaacc
     8041 aagaagacca catttgtctg atagattggt aaagaagtat catcacgtaa ttctctaagc
     8101 tgcgggatat aatctctcaa agacacatcc tcggttgacg attcgcgaat aatgttccct
     8161 tgttcccaaa taaacatcac gactaagatg atcaaaccaa tcagaacggc tacaaaaccg
     8221 cctcggaaga atttgacaac acttgagata aagaaaacga cttctatcgc accgaagaaa
     8281 aaggtaacta aatatgcaag ccaacgagaa tgcccatttt ggataagata aaagtaaagc
     8341 agtgctgttg tcatcaacat cgtcacagtg atcgatagac cgtaagcagc ttccatatga
     8401 tgagacgttc ggaatgtgac aaccactaga gaacaggcga tccataaaat cagattgact
     8461 gctgggatat acatttgccc gatactgttc ccaggataca tgatctttaa ccgaggcagc
     8521 agtttcaact tgattgcttc tgaaactagc gtaaacgaac ctgtaatcaa tgcttgcgaa
     8581 gcaatgactg cagcgactgt tgcaaaagca acgccgatca cgatccaact ttgaggcatc
     8641 atttggaaga atggattcag gttcttgatt tgctgtgctt cagggttttg ataaacattc
     8701 aacaaccacg cagcctgccc aaaataattg ataaccaaac aaattttgac gtaaggccag
     8761 ctcagacgaa tatttcgttt gccgacatgt ccaagatcgg aataaagcgc ctctgcacct
     8821 gtcgtagcca ggaaaatatt tccaagaatg aacaagccta atttgttatc tgcactaaaa
     8881 agcagctgga tagcataata aggattcagt gcacggataa ctgtccagtc ttgactgaag
     8941 ttcattaatc ccattacgcc taaaaaagta aaccaagcga acatgattgg tccgaatgct
     9001 tttccgacaa tatctgtacc aaagcgttgg accatgaata aaacaaaaat aataactaaa
     9061 gtgataatga cgatcacgtt ctggttatta ccgaaccggt caaaaaactg cggaattcct
     9121 cgcaagcctt caatcgcagt cgttaccgtc acagcagggg tcaatacccc atctgctagt
     9181 aaggcagctc ctccgatcat tgcaggaatg atcaaatatt tcccaccttt tcggacaagt
     9241 gtgtagagtg agaaaattcc accttcacca tggttatctg cattcaatgc aatcacgaca
     9301 tatttgattg ttgtcagtag agtcaatgtc caaaaaatca atgagactga tccgataaca
     9361 aaatcaggat tgattcctga caatccgcca ttatcttcaa caatcgattt cataacgtaa
     9421 agcggacttg tcccgatgtc tccgtagacg actcccatcg ctacaagcag gccagccatt
     9481 gatatctttt tggtattgtg cgttgttgcc acgtttttcc ctcatttctt gttatatgga
     9541 tatcctttag gtaagcttga atgatagatg atattcttat ccatgacacc cgctttccta
     9601 aattgcttct aattatccaa gtaacacact gaagtgtcaa cttatttgaa taaaattatt
     9661 ctttctttgg acgttctctg atacgtcttg ccacaaatga ataaagagca aggcaaaaaa
     9721 ttgcacccaa taatgctggt atcaaataaa aaccgccgag ttccggtccc agtggtccta
     9781 gtaaaaattc gccgagccaa ctacctaaaa aaccgataat gatatttcca gatacgcctc
     9841 ccgggacttc ctttcctaaa attgcgccag ctatcaaacc taatataccg ccgataaata
     9901 acgaccataa aaaattcagc atctcctttc cctcctttat ccatatttct cacttttatt
     9961 ttacgcttta ttcagaagga ctccaaaaat atgcgccaag aaactccaga aaaaaagaag
    10021 ttgtaacaaa agtgttcagc ttatttccgt agaagctgct tctggaacac cgtgaatcag
    10081 aggttgtgaa atcagcggtt tgacctgagt attagagaaa caaacggaaa aatagttcct
    10141 catattttgc cgttttttga gctaatatcg agggacagct gattgaacat cgtttattgg
    10201 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa cagccaagta aaaacagctc
    10261 ctaatgtttt taacttggct ggacttatta ccgcagatgc aagcttttga acaccgttta
    10321 ttcgaaaaaa aaggactgtg acacggcttt tgtcacagtc cccttttttc gaataattat
    10381 tgtccccctg tcaccttcac gatcacaagt acattattcc tatgaattaa attatttttc
    10441 ttcatttttc gttgaaccat cttcgttcaa cattgctttt cttgacagat ttacgcgtcc
    10501 ttgtttatcg atttcagtta ctttcacaag gatctcatca cctagtttaa caacatcttc
    10561 gactttattg acacgatcgt ttgctaattg ggaaatatgg acaagtccat cttttccttt
    10621 gatcaagttg acgaatgcac cgaatttttc gatacggaca actttcccta gataaacttc
    10681 accaactttg acttctttgg tcaaatcttc gatgatcttg atagcttttt tgatcatttc
    10741 tgcatcagct gaagcaatac ttacttttcc atcttgatcg atatcgattt tcacaccagt
    10801 ttcatcgatg attccgttga tcgtatcgcc gcctttaccg ataacatctt tgattttagc
    10861 aggttcgatc tggatcattt cgatttttgg tgcatattgg cttaattctt cacgtggagc
    10921 agcaatcgtt gaagtcaatt cttctaagat ttccatacgt gcttgttttg cttgagttaa
    10981 tgcttcagtt aggatttgtt ctgtgattcc ttgaatcttg atatccatct gtaaagcagt
    11041 gataccatct tttgtaccgg caactttaaa gtccatatcg ccaagatgat cttccagccc
    11101 ttggatatca gttaggatcg tatagttttc accatcagaa acaagtccca tcgcaatacc
    11161 ggcgactggc gctttgattg gtacacctgc atccatcaat gctaatgtgc cagcacagat
    11221 acttgcttgg gaagaagaac catttgattc caatacttct gctactaaac ggatcgtata
    11281 aggaaattct tcttctgaag ggattacttg tgctaacgca cgttcaccta atgcgccatg
    11341 tccgatttcc cgacgccctg gagagcctgc acgtcctgta gaaccaacag aaaattgagg
    11401 gaaattgtag tggtggatga atcgtttgct gacttccacc cctaaaccat caatgatttg
    11461 gtgctctcct agaggtgcga gtgtacaagc tgataaagct tgtgtttgtc ctcgtgtgaa
    11521 caaacctgat ccatgtacac gtggcaataa gctgacctct gatgacaatg gacggatttc
    11581 atccaattta cgcccgtcag gacggatctt atcgatggtg atcaattcac gtacgacatc
    11641 tttttcaaga tcttctgtga tttgtttaac ttctttcaac aagtgatctt catcttcatg
    11701 acctgcaaat ttctcagcat aagcttcgcg gatatcgatc ttcacctgct cgatattatc
    11761 ttcgcgagca agtttttctt cagtcattac tgctgctttc attgtagcgt aagaagcatc
    11821 aaagatttct tttttcaata cttcatcaac ttgcagtaaa gtcacttcca ttttttcttt
    11881 ccctactgct tgaacgattt cttcttggaa agcaactaac tctttgatag cgtcaaaacc
    11941 aaacagcaat gcaccaagca tgtcttcttc tgaaacttct ttcgcgccgc tttcaaccat
    12001 attgatggct tgtttcgttc cggcaacagt caattcgata tctgtttgtt ctgcttgttc
    12061 tactgttgga ttcaagacgt actcgccatt tacacgacca acttctacgc ctgcgattgg
    12121 gccgtcaaat gggatatctg agattgatag tgctaaagaa gaacctagca ttgctgccat
    12181 agctggcgag cagtctgttt ctacactcat cacgatgttc gttacttgga cttcattacg
    12241 gaagccttct gcaaacatcg ggcgaattgg acggtcgatc aaacgggcag tcaatgttgc
    12301 ttccgtactt ggacggcctt ctcgtttgat gaaacctcca gggattttcc ctgctgcata
    12361 cattttttct tcataattga tcgttaatgg gaaaaagtct gtatcttttg cttctttaga
    12421 ggccacagct gcacttaaga ctactgtatc tccataacgg actaaaacgg ctccgtttgc
    12481 ttgttttgct agctgaccga cttcgatttg taagggacgg ccgccccatg tcgttttgaa
    12541 tacttgtttt tctgacataa cttctccttt tccttctcgt gaaagcaaga cgctactaaa
    12601 caaatgaaaa ctgccgaaag ccgtcttttg agcagctttc atttggttag taggagtcca
    12661 tctagcttga tcacggaatt ttacttaatt gatatacgag taaaaaaagt gagattcatg
    12721 tgaatcccac tctttttgac taaaattaac gacgcaagcc taaacgtttg atcaattcgc
    12781 ggtaacgttg aacgtcagtt ttacgtaagt aagctaacaa gttacggcgg tgaccaactt
    12841 ttttcattag gccgcggtat gaatgatggt cttttttgtg cacgcgtgca tgttcattca
    12901 agtggttgat ttcttcagtt aatacagcga tttgtacttc tggagaacca gtatcccctt
    12961 catggcgagc gtattcgttg atgatttcat tcttgcgttc ttttgaaatt gccatttctt
    13021 tcacctcttt cgattattcc cctgcgactg agtaaaacgt tggtgattcg cttaaccaag
    13081 tggcaggtca tgtgcctaga gcacacagct atactttacc tgaaaccggg ttgaaaatca
    13141 agtagttaat cattaagaaa aggtagtttt caaacaatct tactactact tttccatttt
    13201 tgtggtaaac tataatgcga aaatagactt gaaacacagt cttttaagaa aggggtacat
    13261 attccatgat tacaatggat gatatcattc gtgaaggaaa tccgacctta cgcgaagttg
    13321 caaaagaagt ttctcttcca ttaagcgaag aagatatctc tttaggaaaa gagatgcttg
    13381 agttcttaaa aaacagccaa gatccaatca aagctgaaga actacactta cgaggcggtg
    13441 ttggcttagc tgctcctcaa ttagatattt ctaaaagaat cattgctgtt cacgtaccaa
    13501 gtcctgaccc agaggcagat ggaccttctc taagtactgt tatgtataat cctaaaattt
    13561 tgagccattc tgttcaagat gcttgtttag gggaaggtga aggctgttta tctgttgatc
    13621 gagaagtacc aggatatgtt gttcgccatg ccaaaatcac tgtgtcttat tatgatatga
    13681 atggtgaaaa acacaagatt cgtttgaaga attatgaatc gatcgtcgtt caacatgaaa
    13741 tcgaccatat caacggtgtg atgttctatg accacatcaa cgatcaaaat ccatttgcac
    13801 taaaagaagg cgtattggtg atcgagtaga gaattggcag gttccttcga tactatgcta
    13861 caagaaagct ttataaaaaa ggggagtgct caaaagctgc acttcccttt tttatgtttc
    13921 tccactaatc gaaatttaga tagacatcta gaaatcgcaa ttccaaaaaa ttctgtgtat
    13981 tggatacgca tcttttctta ttttttctta tttcttccat atgggtgttt atctcagaga
    14041 tgatagaata gtttctagga taaaaagtag cagctacgat gttatccttc gtagaggatt
    14101 cctgcttcag ctagtttttg tttgatgttt ttcagcatat gcttttctgg gtagcggatc
    14161 gtatgcagat ggatgccgcc tgttaattcg gataacaaag tagcattact tttttgataa
    14221 cgtctcataa aggaatcgat atcttgtggc gttttgatgt gcaaagttcc tgctaactca
    14281 ccgtaaaggg gatgttccac aattacatca atgatttcac caccattttc aacgattagt
    14341 ctcagttctt cttctgtttg atcttttcca tgctggacag cgattttact gatgtgccca
    14401 gtattggttt cttctgtttc gaggatataa cctcttgctg ttgccacgat acttttacct
    14461 gcagctcgta gtaaagcaat atcgcctaca atgatctgac ggctgactcc aaaagttttc
    14521 gcaaacttgc tagcactcac tggtttttct gtatttgcca aggtttgcat gatttgtttt
    14581 cgccgtgtct ctccttcgat cacacttatt cctccttcat tttgttttgg tattcgcgcg
    14641 agtgtttcat caaatcaaca tacgtgtctg ttattgtttc cttatatccc ttatttttca
    14701 gcagactaac aactttatcc aatacttgct gctctctttt tgcatcataa actgcttggt
    14761 tttcttcttt tttcacttgt cctattttag ttaccgtatc cattcttttt tctaataaag
    14821 caaccaactc tcgatcgatc atatcgatct tatgacgtaa tgtttcaaga gactcttctg
    14881 ttagttcttc ctctactgtc ttgatgatac gagcaggatt tcctgcaatc actacattgt
    14941 cgggaaaaga tttggtcaca accgaacctg cgccgactac tacgttgtcc cctagagtga
    15001 cacccggcgt gacgataact cctccgccta accaaacatt attaccgatt ttaatgggtt
    15061 ttgcgtactc cagaccgctg ttacgtttca ctggatgtag tggatgcgtc gccgtgtaaa
    15121 gctggacatt cggagcgaac atgcagttat caccgatttc aatcgtgctg acatctaaaa
    15181 atgtacaatt gaaatttgca taaaaattct ccccaacaaa tatattatat ccgtaatcaa
    15241 aattgataac tggctccata tagatttttt tccctgtacg gccaaaagtc tctttcaaca
    15301 attgggatcg cagttccgct gattctgctt ggttgatgat ttggctttga cttcttgcaa
    15361 acatacggtc ggcaaccagc tcaggatcat tggcaaaata aagctcgcct gcaatcattt
    15421 tttctttttc ggttttgaat tcagtcataa tctgctccta attcttgtat ttttttgaaa
    15481 acaaccgctc cgtcttcttg aataaacgta taaggctccg ctaaataaac aggcgtttga
    15541 ttgattacta agattttggc tgacggctgg cgaaactgta ccagatcaca aaacggatga
    15601 acttgaaaac tcgttccaac aatgacgatc agctctgctt ggctgacggc ataagccgcc
    15661 tgctccatga ctccatcttg aaacccttca ccatataaca cgatgtctgg gcgtatttgt
    15721 cctccgcatg cttgatgttt gtcgctgtga agatattctt tccagtctac cgtttgttga
    15781 cattttcgac aatgacattg atacagactc ccatgaaaat tgacgagttg cgggctttta
    15841 gcctttgcgt gcaaaccgtc gatgttttgg gaaacaaccc aaacattttt ttctttcgct
    15901 agatgtgcta tttccaaatg aatgatattg ggttttgctt caggatgata aatctttttg
    15961 acaaattgat agaatttatc cggttcattc accattgctt gatgactcag caagtattcc
    16021 ggctgctcca tcccgtggta gattcctgac aaagatcgat agtctggcac tccagaaggt
    16081 gtggataccc ctgcaccggt caaaaatgta atttgctgat aagctaatat ctcttttgct
    16141 gcttcgtcta ctgttaattg tttcatgttt tgtcacctca ctttccatta tagcccatac
    16201 tcgaacaaat ttattgttga aaagtcagaa aaatgggaat aaaaaagtgt tatgggcatt
    16261 tgagcaattt atcacaatgt tcactgacaa aagaatgaaa acgtgttaca atactgctgt
    16321 ataaaagtga ggtgaatcga tatgttacca ttctttattt attggggcgt tattctggct
    16381 tgtatcgcct ggttagcgtt aagcgtttat ttctctgttt tttatcttgt acgcaaagaa
    16441 aatggaaatc tttgggcttt tgctttattc aacgtgattg ccgcaattgt tttagccatt
    16501 acattagccg tatatcgaac atggggctgg ggaatcaccc aatactcaag tttgatttat
    16561 ctaatattag ccatttatgg cgtcgttgtt cttttgcaag cgatcctagg acgtgagcca
    16621 aagaaagcgg cagcttaaat gatcgagatg gaactggaca caggaaattt tctgttctag
    16681 ttcttttttt attgtattac atacattttt gtgtataatt atactatcgt ttgcaatgga
    16741 tagatgattc acattttgat tgttttttcg gtaaaagtaa agatttctat atttatcagt
    16801 attttttcaa aaaccagcag ttatagattg acaaagcctc tcgagtatcg taaacttttt
    16861 ttgtataaat aactgaatac gagatgcctc aatcaatgag gtagaggtcg cgagaatcat
    16921 taaccctgtg gagtgaagca aacatggaga agcaggaata gggaggatcg ccgaaatgtg
    16981 cacttttttg cttggagtgt atgttgggac gcaagttaag agcttgcgga ctgtcttagc
    17041 agtgatgcta agttgcgcta tgttttgtga gaggtttatc accttatgga attttagcgg
    17101 cctttttata tctataaatc ggtcgctttt tattttttca gataaagctt taccgcattt
    17161 catctagacc gctcgtgtat catataatca gaaagggaga aaaaaatgaa aaaaaatatg
    17221 gtttcagttg ccgtactatt tgcttttgtc ttctcactat tcagtgtggg atctctggca
    17281 aatgcagatg aaaaaacacc gagcgatgag tttcgcgtag gtatggaggc tgggtatgca
    17341 cccttcaact ggtctcaaca aacagatgag aataatgcct tgccaattca aggccaaaat
    17401 agttacgccg gcggttatga tgttcaaatc gctaaaaaag tagcagatgg tttagggaaa
    17461 aaattagtca tcgtccaaac gaaatgggat ggtctggctc ctgcccttca atcaggcaag
    17521 atcgacgcga tcatcgccgg aatgagccct actgctgaac gacgaaaaga aattgatttt
    17581 accgatcctt attacgaatc acaattagta gtagtagttc aaaaagatag caaatatgca
    17641 aaagcaaaaa gtttagcaga tctttctgga gcaaagatca ctgctcagtt aaatacattc
    17701 cactatactg tgatcgatca gataccagat gtgcagaaac aacaagcaat ggataatttc
    17761 tcagcaatga gaacagcttt agcttctgga atgatcgatg gttatgtcag cgaacgtccg
    17821 gaaggtgtaa cggcaactag tgtgaacaaa gacttggaaa tgcttgaatt cagcggtgca
    17881 gatggcttcc agacaaaccc ggaagatgtt cagatttctg ttggtatgcg taaaggcgac
    17941 ccggatatcc aaaaagtaaa ccagattctt tctggcatct ctaacgatga acgaaccaaa
    18001 attatggacc aagcagtcaa agatcagcct gctgcaactg atagtgaaga aaaacctggc
    18061 atcatttctg atttcactac gatttggaaa caatacggca atatgttctt acgaggtgct
    18121 ggacttacct tgttcatcgc attgatcggg acagttgtcg gtactacact tggattactg
    18181 attggtgtct tccgttcggt acctgaatca ggaaatgcac tgactcgctt cttccaaaaa
    18241 atcggaaatg cacttctttc tatctatgtc gaagtattcc gcggaacacc gatgatggta
    18301 caagcaatgg tcatcttcta cggtctggca ctcgcttttg gcatttcatt gaaccgaacg
    18361 attgccgctt tgtttattgt ctctctcaat actggagctt acatgacaga gatcgttcgt
    18421 ggggggattt ttgcagtaga tgaagggcag ttcgaagctg cgcaagccat tggtatgacc
    18481 catggccaaa cgatgagaaa agttgttatt ccacaagttt tacggaatat cttgccagca
    18541 acaggaaatg agtttgttat caatatcaaa gatacagcag ttttaagtgt aatcggcgta
    18601 gctgatttgt tcttccaagg aaactctgct tccggtgcga atttccaatt cttccaaaca
    18661 tttacgatcg tcgggatcat ctacttagtc atgaccttta cgatcaccag aatcctgcgg
    18721 gcggtagaaa agaaaatcga tggtccttca gcttatacca agcttgaaga aatcgacaat
    18781 tcaaatttgc aggaataagg aggaagaatc atgaatgaaa aaattattga aatcaaacat
    18841 ctaagaaaaa gcttcggtga aaatgaagta ttgaaagata tcagcgtaac agtcaataaa
    18901 ggtgaagttg tgacgatcat cggttcttcc ggttctggta aatctacttt cttgcgctgt
    18961 atcaatttac tggaaaaacc aacaggcggc gagatcattt ataatggaga aaatgtatta
    19021 gctcctaaat ataatttacc taaatatcga acgaatctag gtatggtttt ccaatccttc
    19081 aacctgttca acaatatgaa tgtcttggaa aactgtatgt ctggtcaaac aactgtcctg
    19141 aaacgagata aagaaactgc caaaaaagta gcaatcgaaa atctggaaaa agttggtatg
    19201 gatcgttata tcgaagccaa accagcacaa ttatctggtg gacagaaaca gcgtgtcgca
    19261 attgctcggg cattatcaat gaatccagat gtattgctat tcgacgaacc tacttcggcg
    19321 ttagaccctg aaatggttgg cgaagtgctt aatacgatca aagacttagc acatactggc
    19381 ttgacaatgc ttatcgtgac gcatgagatg gaatttgcaa aagatgtatc tgaccgtgtc
    19441 atttttatgg ataaaggtgt gattgcagaa gaaggtacac cagaagatat ctttgtccat
    19501 ccgaaagaag aacgtacaaa agaattcctt tcacgtattt taaatgctta ggatcaatag
    19561 ctgattggga caaagagctg cggtgtttac cgcagttctt ttttatgaat tactcataaa
    19621 aggtaaattt ctgaa
//
LOCUS       DACCVH010000051        19311 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.051, whole genome shotgun sequence.
ACCESSION   DACCVH010000051 DACCVH010000000
VERSION     DACCVH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.051"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            172..1599
                     /locus_tag="IVV98_001865"
     CDS             172..1599
                     /locus_tag="IVV98_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7807504.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1691..2056)
                     /locus_tag="IVV98_001866"
     CDS             complement(1691..2056)
                     /locus_tag="IVV98_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP7807505.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2053..2418)
                     /locus_tag="IVV98_001867"
     CDS             complement(2053..2418)
                     /locus_tag="IVV98_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP7807506.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2610..2858)
                     /locus_tag="IVV98_001868"
     CDS             complement(2610..2858)
                     /locus_tag="IVV98_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807507.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2857..2985
                     /locus_tag="IVV98_001869"
     CDS             2857..2985
                     /locus_tag="IVV98_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP7807508.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3042..4736
                     /locus_tag="IVV98_001870"
     CDS             3042..4736
                     /locus_tag="IVV98_001870"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAP7807509.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4836..5009
                     /locus_tag="IVV98_001871"
     CDS             4836..5009
                     /locus_tag="IVV98_001871"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807510.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5387..6520
                     /locus_tag="IVV98_001872"
     CDS             5387..6520
                     /locus_tag="IVV98_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP7807511.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6551..6871
                     /locus_tag="IVV98_001873"
     CDS             6551..6871
                     /locus_tag="IVV98_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807512.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6900..7364)
                     /locus_tag="IVV98_001874"
     CDS             complement(6900..7364)
                     /locus_tag="IVV98_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807513.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7496..8750)
                     /locus_tag="IVV98_001875"
                     /pseudo
     CDS             complement(7496..8750)
                     /locus_tag="IVV98_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(8779..9096)
                     /locus_tag="IVV98_001876"
     CDS             complement(8779..9096)
                     /locus_tag="IVV98_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7807514.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9122..9442)
                     /locus_tag="IVV98_001877"
     CDS             complement(9122..9442)
                     /locus_tag="IVV98_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807515.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9906..11321)
                     /locus_tag="IVV98_001878"
     CDS             complement(9906..11321)
                     /locus_tag="IVV98_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7807516.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11338..12654)
                     /locus_tag="IVV98_001879"
     CDS             complement(11338..12654)
                     /locus_tag="IVV98_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807517.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12804..13502)
                     /locus_tag="IVV98_001880"
     CDS             complement(12804..13502)
                     /locus_tag="IVV98_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP7807518.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13791..14780)
                     /locus_tag="IVV98_001881"
     CDS             complement(13791..14780)
                     /locus_tag="IVV98_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAP7807519.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14860..15693)
                     /gene="msrA"
                     /locus_tag="IVV98_001882"
     CDS             complement(14860..15693)
                     /gene="msrA"
                     /locus_tag="IVV98_001882"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7807520.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15868..17502)
                     /locus_tag="IVV98_001883"
     CDS             complement(15868..17502)
                     /locus_tag="IVV98_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807521.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(17489..19177)
                     /locus_tag="IVV98_001884"
     CDS             complement(17489..19177)
                     /locus_tag="IVV98_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807522.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT         6136 a         3767 c         3200 g         6208 t
ORIGIN      
        1 ttcgcaattt attttttaat agaattatct gttttccaaa ttttataaca taaaaaacct
       61 tttttaacgg catttatatg ctttttcaga aattaactga tgatttcaaa aagaaaacat
      121 gtcataatat ttcccatatt gtgcaaaaaa atacaaggcg gaggctctac tatgattgaa
      181 gaatatattg agaaaaatat tttaagacag ctgtttttat gtgggcaatt ctatgtaaat
      241 aaagaagtca atctagaaaa gctctccaat ctcctgcatg tttgcaaaac cactttactc
      301 aatgatatca ataacataaa aaaagaattt gaagaacaga tcgcttatac acatcgggaa
      361 aaggaccgtt acactttata tttttcagaa catatacctc gatgcaagat catgcagcaa
      421 ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt atttggaaga agatgaacct
      481 gattatcttc aattaactga atgtgaattc atctctgtca gcaaagctta ttcattaaaa
      541 aaacaagtat tagcttattt taatgactgc gggatcgaaa tcgaccgcta ctcccctcga
      601 ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt cgtatcgttt aggcggtttt
      661 aattcttggg agctacctga atcgtttttt gaacgtgccg atcgtttcat tgaatccgta
      721 acggaaaata gtggcagatt ttatgataaa gaaaataaag aaatcttatc gattggtttt
      781 gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa tagattcaaa atttatcgaa
      841 gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag catgggaaaa cactgatttc
      901 caaacctatt ataaaaaaga agaattcgcc tttattttga cactattcaa tctttgtaat
      961 tatggtttcc attcttatca gttgattgcg gaagactttc aacagctaca ccaagtgttt
     1021 attgacaata ctcccgaaat aaaagaacta gttgctacct ttgaatctca cttcaatcaa
     1081 gaattattcg gaaaccaacc gttcgaacgt gcgctgattc atctgatgcg ttcggcttgg
     1141 gataactatc aattattcat gccagaaaaa ttttatcttt taaatgagga acagacaaat
     1201 ttatataaag aagtccagac aattttttcc agctggtcca gccagttacc ttatgatcta
     1261 cggttgaatc ctaattgcat gcgggctttt gtgatcgaat tgagcggaat tctccgtctg
     1321 acaaaagaac atctgactat ctatatcgtc acaaattcgg atgttcatta tctgatttat
     1381 cgggaagcct tggaagctgt aactactttc gattttcaag ttgcaccaac aatttattca
     1441 agtatatctg atataaagaa gtatgcgcag cagtcctcaa accgggtatt atgtgaacgt
     1501 acattatata caccagatgc ggtccaatat gaaaatatta ttcctatttc gatcaatacg
     1561 atcgatcgag ctatcatttc agctgtgcaa aacaaataag gggctgtgac aaaaatcatg
     1621 tcacagcctc ttatttgttg aagatgccca tttctgtaac aatctcttga tacacgtcag
     1681 gctcacaacc tcacttattt tggacatcta cgggtccgat ctctttattt aaaaaataag
     1741 aaatgatggt tcggataact accaacgccg ctagttggaa aatatcctgc aaggtaggtt
     1801 tgataatcga ttcgatgatc ccagctgaaa caagaatttc caaacttaga agtatatagc
     1861 ctcccaacat ctttttaata gcattgttct cgctgactcg gtcgctttgc acttttgtat
     1921 ggacaaataa atatttcaaa aaatccttga ttgatagaca aacaccccaa accaataaac
     1981 agatagcaaa gatatcaagt cccagtacaa gtttttcgaa atatggaaga agaaactgca
     2041 tcaactctgt cgtcatccta cctctcctct tctttgtttt tctttgtctt ctatttcctg
     2101 attcaagaaa taagaaatga ctgttcgaat gataataata agtgcaagct tcaaaatatc
     2161 tgtccaagtc ggcttgataa ctgactcgat gatatcagca acgactagta cttccaagct
     2221 taacaaaata taacttgcta gcagttttct tgtatctgca ttacgagtat tacgttctgc
     2281 atagtttttc ttgacatgag accaatcaaa aagtttgaat agaacaagaa cgatcccgac
     2341 aattaagata ccgatagaac aaatatttaa aatagcaatg atccattcta gaaattcaat
     2401 taaatttgag cgaaacatat acgctaccta ctttctttta atttgttcct attcttttat
     2461 tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt tctaatgata acggttcgct
     2521 taaatttttc tttttcactc tcccattttt ctccctccat ccataaatcg tggaagtatc
     2581 caaaacaacg tagcaagtta aaataaggct tagtccgtca tcagcttttc aaagaagcac
     2641 tgtctcggtg ctttttttgt acccaaattt ctaaaaatag aaccatacac ctcctcaaat
     2701 cttttcttct tacctaccct atttttattt acaggaaaat cagacacttc ttcttttttg
     2761 tcaaaatttc ctttttcttc tcgtcctatc atttggcatt ctaataaaaa cgaactatcc
     2821 ttggatatag aaagagaaaa caaggaggcg tttttcatga gtaaaaaatt aatcaaagtc
     2881 ggcatcggtt taggtttgct tgcccttggc gctgcatatc taggaaaaaa gacaggacta
     2941 ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa tctagcatcc tatttagttg
     3001 aatcactacg gacatacttg gaagacattg gaggaatcac aatgagaaaa agtaaagcaa
     3061 taatgattgg tgccggtatt gccaatatgg cagcggctgt ttatttgatt caagaaggca
     3121 aatggaaagg ggatcagatc accttttatt cattggatga tcacggttca aatgatggtg
     3181 caccgaccga cactgtagtg gatgaatatt ggaataaaaa ccatccatta gaaaaccaaa
     3241 aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg tacctatgta gatttgatgg
     3301 atctgttaag tcgaatacct tctgttactg agccagggat gactgctgaa gaagatacga
     3361 gagattttga tgcaaaacac cgaacctttg acaaagcacg tttgatggaa ggtggcaaag
     3421 gaatcattga tggcggaaaa ctgggattca ataataaaga ccgtattctt ctgactaaac
     3481 tgattgctat gcctgattca gaagaagaaa aactagacaa tatcactatc gaagaatatt
     3541 tcaaagatga tccacacttt tttgaaacaa acttctggtt tatgtgggaa acaacatttg
     3601 ctttcagaac acgtagttct gctcaagaat tgcgtcgcta tatgcatcaa atgatttatg
     3661 aattcactca aatcgaacat ctagtgggcg tcaatcgaac acgttacaat caatacgaaa
     3721 gtattatgct tcctttgatc gagtacttga aagaacaagg atgcaaaatc attttgaacc
     3781 gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca agatgaaatc actgtgactg
     3841 gtttgaaaat taccaataca ctgactcaag aagaagaata cgttgtggtc gatgaagata
     3901 cagcagttat tttcactaat gggtccatta cagattcagc tactttagga gattacgaaa
     3961 caccagctgt agaaaatatg gattatggtg cagcttctag tctctggaaa aaagccagtg
     4021 aacgtttcta caacttggga aatcctgaca aattctttgc tgatcgagat gcaagcgaat
     4081 gggtcagctt taccctgacg acgaaaaacc atttgttgtt gaatgaaatc acccgtatca
     4141 cgactcaaga accaggaaat gccttgaatt catttatttc aaccacaccg atcacgccgt
     4201 taggccaaaa agatgtcaat atgtctattg tcgtgcatca tcaaccgcat tttacgtctc
     4261 agaaaccaaa tgaaacagtt atttggggtt atttccttta tccaagacga cgtggcgaat
     4321 ttgtggataa acagtatatt aaaatgaatg gaaaagaaat gctagaagaa ctgattggac
     4381 aactttcaaa agtagatcct ggaccagtga atattcgtga aaaagaaaca gaaattttcg
     4441 acagcgtaat aaataatatc cctgtctata tgccttatgc ttccgcgttg ttcaataatc
     4501 gtgccaaaag cgatcgacca aaagtcattc ctaaacattc gaccaatctg gcctttacag
     4561 gagaatttgt cgagcagcct tatcagatga tctttactga acaaagtgct gtacgttctg
     4621 gagaaatcgc tgctttccat tttgcgggta ttcctatgtc ccgtcttgtc aaaacaccgc
     4681 gttacgacaa agatattcct actctagctc gtgccgcaaa aaaaatgttt gaataatcaa
     4741 gaggttgtga aaaagctgcc ctgcatcaag taataagaac aaccaggcta aaacagcttc
     4801 ttatgttttt gatttggttg gacttattac cgcagatgca agcttttgaa caccgtttac
     4861 caagaggtta tgaaaaagct gccctgcatc aagtaataag agcagccaag ctaaaacagc
     4921 ttcttatgtt tttgacttgg ttagacttat taccgcagat gcaagctttt gaacaccgtt
     4981 taccaagagg ttatgaaaaa ggcgtttagt ttcgagtatg aagaaaaatt ttgtgaaaat
     5041 ggttcctcac gtttttgcat aaatttgact taataccgag aaactgatcc cttctgtcat
     5101 aacctctttt tatttatgtc tgtttctttt tgaaaacaac tattttttca acgtttactc
     5161 tcttgccaat ccaacatcat ctaacggata caactatttc aatgattacc attacactaa
     5221 aaaatcggaa acacacctct ccgaacacaa atacataaga ctatagaatg tttcatttaa
     5281 gaaaaaaagc gtttcattat caaaaaggta agatctcctt taaaatgaaa ttatctgtag
     5341 tactaataat gcagacaatt ttatgaatct gaaaggagca tctccaatga aagcagtcac
     5401 ttggcaagga aaacagaaaa tggaaatcag aaacgtagat gatccaaaaa tattagaacc
     5461 aacagatgca atcatccgta tcacagcaac agccatttgc ggctccgatc tgcatcttta
     5521 ccatcatggt gaagcagttt tggaaaaagg gtatgttgta ggacacgaac caatgggaat
     5581 cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa gggcaacgtg tggttatccc
     5641 ttttaatatt agttgtggtc attgtcattt ctgcctgaat cacatggaaa gccaatgtga
     5701 tgaatcaaat ccagatcagt tatatggcgg gcttttcgga tttggcaagt tgaacggtaa
     5761 tcattggggt ggtcaagcgg aatatctaag agttccttat gcagactcta cttcatttgt
     5821 tgtaccagat aatgatcttc ctgatgaaaa agttttattt ctatcagata ttttgcccac
     5881 agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc gatacagttg tgattctagg
     5941 ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt atggctggag cagagcgcgt
     6001 aatcgcagta gatccagtac agcaccgtct agataaagcg gctaattaca atggggttga
     6061 aacttatttc ttagaagaca cggcacaagc tggaacagaa ttgtatgaac tggctaaagg
     6121 tggcgcagat gtcattatcg attgtgtagg aatggacgga ttagagcctg tcaaagaaaa
     6181 agcgaaaaat ttagtaagct tacaaagcgg cacaatctct ccattacaga tggcatcgca
     6241 agctgtcaaa aaatttggaa cagtccaagt aactggtgtt tatatgactc cagcttcttc
     6301 ttacccgctg caagaatttt ttatgcggga tatcgctgtc aagcatggac aggcaccaat
     6361 tatccatcta atgccaaaaa tttacgcaat gattgcagaa ggactattcg atcctacaca
     6421 aatcattact cattcgctgc cactatcaga agcagcacaa gcatatgaga tctttgacaa
     6481 aaaagaagat aaaaatataa aagttgtttt gaaaccttga attcagtaaa aaatacaggt
     6541 gattttcttt atgcccaaaa tcaaacgaaa tacccatgag atcgaaatag gaaaagaaga
     6601 agatatcgaa atacgaggac gtcgcttccg cttctatttc caaaatcgtt acacattgat
     6661 ctcactggct gtcgatttat taaccgggat tttctatatt tttggaagcc ttgcttcctt
     6721 aactaaaatc cccgatcgat atggcaccta tttttatttg gctggtgcta ttttcttgac
     6781 gattcgtcct attctcagaa tcgtaaggaa catttttatt tacgacgaaa aaaaagcaat
     6841 gaagagaaca agcaaaaaaa aagaggcatg agaatttttc aaatctcatg cctctttttt
     6901 caccctatcg tatcactttg atacagacga gcggtcgtcc cactttcttc cttgaccatt
     6961 gtcaaaaatg tccactcgta tcgttcataa aacgtggtat gatctgtaat taagtaaagt
     7021 ttttcgtacc caagttgatg catttctttt ctgatttccg ctaatatccg cttggctatc
     7081 ccctgcttac gcttttccgg ttcaacaaac agggcacaaa gatttggtgt cagatcaggg
     7141 cggttatgga agtcgttttc aatgacgccc gctcctccga cgatggtttc tttttcatct
     7201 aagaccacat accattgagg aatactttcc ttattagcga ttccagtacg aatactttcc
     7261 tcatacacaa cagcaggaac tccccatttt gatgaaaacc aattcgcgct ttgttttact
     7321 aattctgggt gttctcttaa tttgatccag ttatatgtaa ccaatgttta aacctccgac
     7381 taaaataaaa cgtttacaaa aattatacaa gtctttatga aaattagcaa tgacaacaat
     7441 agtgatgtaa aaaaaaaaac ggaaaacaat cacttgttct ccgttttttg attaatcaag
     7501 catctaaagc ttcttttctt ctttcttgga tcgtagctac cttgacgaac ggtagataga
     7561 tcaaaataga aagaaccaaa ttgacagcgg ctagtacacc acctgcaata ctttttgttg
     7621 ccaatacacc gccaataatt ggtggagtta cccatggagg cataacggta gctgctggca
     7681 ctaaacctgt agaagtcgca aagttaagca acactaacta agaccattgg tgtcaaaata
     7741 aatggaatga acatgatcgg gttcaacacg ataggtaacc caaacatcgt tggttcatta
     7801 atattgaaga cacctggcgc aatcgacaag tttgttacaa ccatatatgg tttgttttta
     7861 cgtcctacta aataaatagc taacagtaaa cctaaagttg cacctgttcc tcctaagttg
     7921 acaaagctgt caaagaaagg tttgttcacg ataaacggtg cgctatgtcc agctgcgatt
     7981 gcattaacgt ttgcttcaat ggctggcgca ttgattgttt gcatcaaagg atcgaccata
     8041 ttcgctccgt gtaaaccaaa gaaccataag aatggtgtga taaatgcaag cagtaaggca
     8101 gatggataag agtttgcaag tcccataaat ggttcttgga ccactgtata gaaagaacct
     8161 acgatatcat caacaccgaa tgcagcaaaa attgcagcaa ctaaagcaaa cgcagagata
     8221 gtgatcattg ctggtagtaa tgaagcaaat gcttttgcaa ctgccggtgg cacaccatca
     8281 ggcattttga tgatcaattt ttcatttccg cttaaacgta caaagatttc tgttgaaata
     8341 atcccaacaa taatagcaat aaacaaaccg tttgagctca tacctaatgc tccgcctaaa
     8401 gcgaagaaag agcctaaaga aatcacacct gcggaaacac cgtcttttcg gtagccgtta
     8461 gctaaatgat aagcaagcaa gaaagcaatc aagacagaaa gaatggcaaa tgtaccgttc
     8521 caagcagcag ccccgaatcc tttccatgat tcaccaccaa aaattgagtt catcaattct
     8581 tggaacccgg gaatcggtaa gttattgatc attactgcta atgctcctaa gatcattaac
     8641 ggcatactca ccataaatga gtcccgaatc gcaactaaat gccgttgtgc accaattttt
     8701 gatgctacag gtataaaatg tttctccata aatgcaacaa atttatccat aaatcttccc
     8761 tcttttcttt actgtagatt acgcgttcaa tcgacgatac agatcaatga tctcttttgc
     8821 taaatctgta aaagctatag atgtcatcag atgatcttga ctgtggaccg tcaaaagcgt
     8881 gacttcaacg tgatttcctt gtgcttcttg tgtcagcatc tctgtttgag agtgatgtgc
     8941 ttggactaaa gattcctctg catctttgat tttttcatct gctaaagtga aatcaccttt
     9001 tttcgcagca gcaatcgctt ccattgcatc gctttttgca tttccgccaa acatgatcag
     9061 acccatgatg gcttctagat ttttttgatc ttccatttat tgtatcctcc gataattttt
     9121 attatttgtt tattagtttt tctgcttggt cgagtacttt ttcaccattc atcatgccat
     9181 agtcagccat attgattaca tctaaaggaa tgcctttagg tgctagcttt tcagcaaatt
     9241 gattttgcat aaagcgtact tgcggtccta aaagtaaaac gtctacattt ttagattcta
     9301 gttgattatc cgcatctgaa gcagatacag caaagatgtc tgcttccatt ccttttgctt
     9361 ctgctgcctt ttgcattttt gtgactagga gacttgtact cattccagct gaacatacaa
     9421 gcatgattgt tttcttttcc attttaaaca cgttcctttc tatacttaca cttgtatata
     9481 agcaagtagc gtgccaactt taaaagcgct ttaaaaagtt gatatcatca catttaaggt
     9541 ctataccaag ttgcatacac actaaaaaag aaagcgcaca ctaaacacac aaattaattt
     9601 ttattacctt ttttctttta acgtgcacaa aaaaagttgt gacacaaaac ttgtcacaac
     9661 ttttttcaaa taaacggtat tcaaaagctt gcatctgcgg taataagtcc aaccaagtta
     9721 aaaacataag atgttgtttt tactttgcta ttcttattac ttgatgcagg acagcttttt
     9781 cacaacctct caataaacgg tgttcaatca gctgaccctg ggtattagct caaaacgctg
     9841 gattcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct acaaaaaact
     9901 tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat caaagtctga
     9961 taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc gattcgaact
    10021 aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa tgcccataac
    10081 atatagcctt cgcaatttgc gccttcttct gttgctttga tcaagtaatg caaatgctgt
    10141 ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat atactgttct
    10201 tcatattctc ttcccatacc gttttctgtt atcagccaag ggatattatg ataattttct
    10261 tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc cctggaatta
    10321 ttcattttct tcccaggtaa atcaaagact tcataatatc gttcaggatg gaaaggtgtc
    10381 tcttcattcc attgataacg aggggcgcga acgcgtttag gataatattg attgattcca
    10441 aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg atcgaaataa
    10501 atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtatccttt taccatcgga
    10561 tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg gtcttctgga
    10621 gaattggatc gagcatagac catttcagga tttaaaatac agccaatcct tccaccataa
    10681 tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg ataattccac
    10741 atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa atagcaacgc
    10801 gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc accgtaacga
    10861 tcaaaggcaa tttgagcata cttagcataa aaatcaacta cttttcttga agaccagcca
    10921 tcatattttt ccaaaagaaa agctgggact tcataatgtt ccaaacaaat catcggttct
    10981 acgtctgctt cgatcaaaga gtcgatcatt tcacttatat gctgagcata ttcttcatct
    11041 actatacagt tctcataatc agtaaaaaaa cgagcccaat tgatagaagt ccgataatgt
    11101 gtcagatgga tggatttcat cagatccaca tcctgctggt attgttccat aaaattagtt
    11161 gctacggctg ggccataccc attatgccaa acaaaatgtt catttttata ccagctatct
    11221 ataaacgaat cctgtccttc tttttttcct ttccaacctt ccgtttgcca agcagaagat
    11281 gcagcaccaa gaataaaatt ttttggaata gtaattttca tgatttcctc ctgtttttta
    11341 gatcccatca ttttccacac gatttgctac ttttacaaat ggcagataga tcaaaataga
    11401 aacaataata caaacaagtt gcgtaataac tgcaccgata tttcctgctg ttgccagata
    11461 agcattgacg atcggcggca ttggccaagg gaccattaca actgctttcg ccgcaaatcc
    11521 taaagcggtt gcaaaataac caatcgttcc agtgataaga ggcgttaaga taaacggaat
    11581 agctaaaatt ggattcagca tgatcggcat accaaaaata actggttcat tgatgttgaa
    11641 gatcccagga gcaagggata acttggtgat ttgtttcata tcttcccgtt ttccaactaa
    11701 caatactgca atcagtaaac cgatcgtgac tccagacccg cccatactca tatacatatc
    11761 ccaaaatggc atagtaataa tgttcggtac ttcttttcca gcttcaaaag cttccgtatt
    11821 tacagcaatt gccgctaaaa gcaacggttc ccgtatcggc ttcaccattt gatttccatg
    11881 gataccaatc acccaaaaga cttgcgcaat aaacatcaat agcaaaatac ccggtaaccc
    11941 ttgtacgaca ccttctaatg ggcgttgtac gacattgtaa atgatatcat aaaggtacat
    12001 tcctgtaagt tctttgatga taaatcccgc agccgcgata cccgatacag tcagaatcgt
    12061 cgggaataaa gcagaaaaac tagcagaaac attcgttggc acggtatcag gcattctcag
    12121 ctgtagtttc ttctgtttcc tcaaccagca ataaagttca atagaaagga tggagaccaa
    12181 cattcccaaa aataaccctt tcgtatctgt atattgttta gccaatacgt tttctactat
    12241 aacagtctga ttttcattca ctaattcata aacagttgga ttaacagata aataagacat
    12301 cactgcgatg ataccaggga atacaccatc cactttattc agcttggcta attcgatccc
    12361 tatcagaaaa acagcataga tggtcaagaa acttagtgtg acatagctga tggcagatgc
    12421 gataggcttt aattcttcta aaaaacgcaa gaaacttatc tgtgctaagc cattttccga
    12481 gtcaaagacc attgctgaaa acaatgtgcc aaaagcaccc gtaataatta ccggaatcaa
    12541 tgcagcaaat gcgtttttta tcaccatgat ataccttaaa ttattgattc tcgttgccac
    12601 gttccctaaa acattggcta atttatccat aaaactcatt ccagatcccc tcattcctgc
    12661 ttcttctcct tgacgtcatc tctttttgtc tattagtcag cgcttacatt tcgatgaaca
    12721 gaaactattt actcctcttt tttaccaaat ataaaacaaa aattcatctg atgtatttat
    12781 cataaaatac atcagatgaa ctgtcaatta gtttcttttt ctcctattat tttctgtaat
    12841 tctctccgat ttattgccat atggacagtc attgcatcaa acgcagcaag tgcattccgc
    12901 ctttcgatgg cctgaacgat ctctgtatga atatcgatcg tctcgatttt cagatgctgg
    12961 atatcataat ttttattaaa caaagcaatt gattcattaa tgattgggat aatatgcagc
    13021 aaggctacgt ttccgctagc ttctgcaatc atcgtatgaa aatcgatgtc taattgaaca
    13081 tgttcttgtg tgccttctcg aaaagaagtt tcaatctttt gcgttaattt tttcatttgg
    13141 acgatttgat tcttcgttgc atattccgct gccaaacctg ccatcttagg ctccaataaa
    13201 tatctcagtt caaataagtc tcgtatcatc cgatcctgat cttcaatcaa agaaaaaccg
    13261 agtgggtcat tggcaatccc tcgcttatca ctgacaaatg tccccgctcc ttgccgaact
    13321 tcaaggatat tcctggaagc tagagcccgc acagcttctc gcaccgtgct tcgccccacc
    13381 tctaaataat cggacaattc atattcattc ggcagtttat ctcctacttg caactgcatt
    13441 tcctttaaat atctaaggat cttgtcagta gttacttcta ctagggtttt attttcttcc
    13501 aaaccacata cctccttttc atctgatgta ttttttcgta attattataa cacgtttgaa
    13561 tcatctgatg attttttgta tacaaaattg attaatccgt tcatagacat acaaacgaag
    13621 aagatattta ccataaaaaa gactaggata aaattcactc ctagccttcg atcattttta
    13681 ttttgaacga caaaaaatat gatgttcaat aacagacgat cttcattcga ttcttgatgt
    13741 catcttttgt tttttttaat atatggataa aaagtttgat tacatcgttt ctattctaga
    13801 atttggtcga ttctcaattc ttcttctggt gagaaatcta aattatccat cattcgaaca
    13861 ctttcttgta actgacttaa ccgacttgct ccgaccagta cacttgtaac agatttttgt
    13921 cgcaaattcc atgcaagggc catttgcgct aatgattgtc ctcgtgatac ggcgattgtt
    13981 tgcagtgctt tgattttttc cagagttgat ccaacttgtt cttctgaaag gaatggtatt
    14041 tccttacgat gtgctctaga atcttcagga ataccatgta gataacgatt tgtcagcaac
    14101 ccttgagcaa gcggactgaa cgtgattgcc cctagccctt cttcttctaa tactggagat
    14161 agatcgtctt ctagtagtgc acgagaaaac atattgtagc gcatctgatg aataatgaac
    14221 ggtgcttcct ttctttttaa aatttcagtc attttttttg tatcttctcc attatagttg
    14281 gatataccaa tatataatgc ttttccttgt cttacaagtt gcatcaaagc ttctgctgtt
    14341 tcttccaaag gtgtatcagg gtctgggcga tgatgataga agatgtcaac ataatctagc
    14401 cccattcttt ggagactttg gtcacaactt gaaatgatgg atttacgaga gccccattcc
    14461 ccatatggcc cttcccacat atgataacct gctttgctag aaataatcag ttcatcacgg
    14521 taggcttgaa aatcttctct aaaaatacgc ccaaagtttt tctctgcagc tccagcaggg
    14581 cctccataat tattcgcaag gtcgaaatgg gtaattccca tgtcgaatgc gcctcttaaa
    14641 atctctcttt gattatggat aggatcataa tcaccaaaat tttgccataa tccgagagat
    14701 aaaatcggta atttcaaacc tgaatgaccg gatttacgat attccatttt ttcataacgt
    14761 gcactatctg caatatacaa tttttctcct cctcatcaaa tctttttaaa acgctttctt
    14821 ttttctattt ttagtttact acattttaaa gaaaaggagt taatcaaaat gattttttcg
    14881 tatatttttt tgccatttgt tttttactcg ttgatagatc agaaattgat tacgtgcttg
    14941 ctggattttt ttataacgtt tcggttgttt tttgtaaaat tgctgatgat agttttctgc
    15001 tggccaaaac gtaccggctg gttcgatttt tgtgacgatt ggttggtgga aagttcctga
    15061 actgtctagt ttctgttttg attgttccgc taattctttt tgtcgttcga cttgataaaa
    15121 aatcactgga cgatattgct tccctctatc ttgaaattgt ccaaatgtat ctgtgggatc
    15181 agtaatttgc caatagattg tcagcaactc gctataactt atttctcttg tgtcataaat
    15241 gatctccaca gcttccacat gacctgtgta accaccactt acttgatcat aatttggttt
    15301 ttcaacatgt ccgcccgtgt atcctgacaa aacagatagg atcccttttt tcgattcaaa
    15361 cggctcgacc atacaccaga aacatccccc tgcaaatact gcacgttctt gatagtcagc
    15421 atcttgcatg gcatgcttgg aaaagtcata tttttgctcc ttatcaaatc cttccgtaat
    15481 caataaataa aagtccatta catcaggcgt cagattcatt cggatagcta atggacgtag
    15541 tgttgcttct agttttgata actgttcttt aacggatata ttttctctta tgtcattctt
    15601 tgtctgaatc aatacttttc gttcccaatc tcgtgtattc ggattcaaaa tcagattata
    15661 aagtgtttga atgaatattt gttcctcatc catagattct cctcctttcc gaagaagaca
    15721 agctagtgac tttagctgta atttatcata aagtgaggaa ataagcgatt acttcatccc
    15781 cctacagatt tttcgtataa aaaagagaga atccttatcg acagattctc ctttttaatc
    15841 aatttatttt ataaatgaaa agttaattta ccttttatgg aaaactattt taaaaaataa
    15901 acataaatat gcagttaatg taacaagata agaaataata gtcgttactg tataacttgt
    15961 gcttacttta atatcagcaa ctcctttgac tccgcttatt tgtaccaatc cattagcatt
    16021 cacctgctcc tttacaggtt gatgatttat ttctacattc gttcctaaat aagcatatac
    16081 aggaagtgtg attacttggc tcttctcatt agttactcta tatatgatag aactaccagt
    16141 tgttttataa ggaaggttta cccattgact gccaatcttt gcttcgtgtt ttattatatg
    16201 ctccttattc tccaatgaag cgataggaga ataatcatat aaaaaataat ccattccttt
    16261 agtggtatac gcctctactg tttctttgtt tacaacaata tgtcccggct gagaaattat
    16321 tttttgattg aaattttttt tactagaaac agttaaagtg attaataaca aaacagtcat
    16381 aaataaataa aatagttctc ttgtcttatt gtatcttcta tttttgaaaa atatcatcgt
    16441 taatatcaga gaagagaata ttatttgcaa gcttaagatc cgccaaggaa attgtaacaa
    16501 tttggctggc gtattttgca gaagatacca tggcaccaaa ctagttgtag ctagccaagt
    16561 caaacacgta ccataataaa tctttttttc tatgtttgtt aattttttaa ataaaatcag
    16621 gggaatacat aaagataaca gaccaactag tcccattgag taagtagtta agtcgttgtt
    16681 catagcttca gtcagactat cgaacacatt agatgcatga gcatataaat ttgtcacgct
    16741 aggtttgttg attttttggt agagcatttg ttcaaacatc ggataccaaa aagcactcgt
    16801 cagaaccaat gtcattcctg ccgcactaaa taatttttta aatatagcaa taaaatctgc
    16861 attcttgaaa cctttagaaa ccaaacgaat aaaaataaaa atgataatta atgctgtact
    16921 cattaatgtt gatagtacat ggctgtacac tagcaaactc atactcaatg ctagctttac
    16981 agacggatac ttttcttctt ttccagagat gatttgataa gcataaaata atacagggat
    17041 aacaagtgtt attgcgatag cttcggcaat tgcggaacga tagtagatgt ctactgtccg
    17101 ataagcagag aaaatataga gacaactaaa taaaaatgcc gctttttttt gttttaaaaa
    17161 ccgctcgcca taatgataag ctacgagtgt tgtacacaag ttcaataacc aaacgtaaat
    17221 aatatagctt acaatcaaat tttttgtcat ccaatataac attacagctg gaaaaaaagt
    17281 cagaaaggga taaaaataat ttacaccata tccagtataa ttgaatgtct cataattaat
    17341 cggactggta aaaatagtcg ataacccctt gattcgagat aagtgaaaag aaagatctcc
    17401 agtggtataa atactctgtg tatttttgaa aaagatgaaa gaatatatac tactaactat
    17461 aattaatcca ctcaatatta ctactttttt atttattttc attcttcttg tttatctcct
    17521 ttttagtcac atatcgagaa tctttcaact tattaggtgc aaatcgttta aaacttgaat
    17581 acaccactaa acaataagtc agaatactga tccataaagc catgagagca gttggagtat
    17641 attttgttgt aatttctatc ttattttctc cagcatttac atccacattc actaagccat
    17701 gttttttata agagtcattt acgactttac cgtttacttt tacctgtgta cctaaataag
    17761 catatactgg tactgtcact ttttgctttt tgttgcttgc cactgtgtaa gtaatgttat
    17821 tatctgcagc tttatacttc cctttttccc acgattctcc tacttttact tcatgttttt
    17881 ctaagtgagg cctttctttt atcgcttctg ttggggcgta atcgtataat cctcccatat
    17941 ctgatgttgt ataacgtggg agtgtttctt cattgataac aatatgaccg tgttttgatt
    18001 ggataacttt tgcgtaattt tcttttgctg ctatagacgt gacgagtaga aacaccacag
    18061 tagcgccaat gattaaccat gaatattttt tattcatagt ctttttcata aaaacaagcg
    18121 ttatgatcat tgaagaaaaa aagatttgga tacctaagat acgccaagga aactggagta
    18181 agcttatcgg tgttttttga aacaaaaacc atggaaataa attagttacg catacccatg
    18241 tagaaactac gccaacatag atgatttttt cttttttctc catttctttc agtatgaata
    18301 aaggaaaaat caacgcaacc aatcctaata accccatagt gtatgttgta atatcgttat
    18361 ttaacgcttg aatgatacta tctgaaatag aaagtgcttc tagctgcaaa tctgttttga
    18421 agggactgtg tatttcttga taattcatct gctgcaacat aggataccaa aaatagctag
    18481 ttaatgcaca agtcaaaaaa acagccttta ctaaattcac gaccacaaat tttatatcgt
    18541 tttttatttg cttgcttaaa aacaaacgaa ctataatcat acaagcaatc aatgcactac
    18601 acaatagtgt agttaagaca tgagtataca caagtagact tatactgaca gataaagcga
    18661 tgactttttt ttctctattg aatatcaatc cataagcata atataaaaca gctgggataa
    18721 tcgtaagagc gattgcttct gcaattgcgg atcgataata gatatcaact gttcgataag
    18781 ttgcaaaagt atataaacaa ctaaataaaa aagcagcatc tatcttttta aaaaactttt
    18841 ctccataata aaaactaatc agaatcgtac aaatatttaa taaccaaata tatagaacat
    18901 aacttaatat taagttattt gaaattccat aaaaaacgac tgcaggaatt attgtaagaa
    18961 aaggataaaa atagttcagt ccatctccat aattgttaaa tgttgtatag ttgattggcc
    19021 cttcaaaaat agaagataac cctttgattc gtgaaagatg aaaagataaa tcacctgttg
    19081 tataaatttc ttgagcattt ctcataaaat ttactgaata taaagtacta agtaagataa
    19141 gaactactaa aagaaatgct tttttactta ttttcataga tttgttgttc tcctttttta
    19201 attctatttt cagtatacta gaattgtctt tttttaataa gttttgcgtt aaatttttca
    19261 tagcactagt atgatatact agaaaagaat caatttttat tacttttaaa t
//
LOCUS       DACCVH010000052        18950 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.052, whole genome shotgun sequence.
ACCESSION   DACCVH010000052 DACCVH010000000
VERSION     DACCVH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.052"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            62..1108
                     /locus_tag="IVV98_001885"
     CDS             62..1108
                     /locus_tag="IVV98_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807523.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            1110..2369
                     /locus_tag="IVV98_001886"
     CDS             1110..2369
                     /locus_tag="IVV98_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP7807524.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            2375..2956
                     /locus_tag="IVV98_001887"
     CDS             2375..2956
                     /locus_tag="IVV98_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP7807525.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(3038..3913)
                     /locus_tag="IVV98_001888"
     CDS             complement(3038..3913)
                     /locus_tag="IVV98_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7807526.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            4061..4393
                     /locus_tag="IVV98_001889"
     CDS             4061..4393
                     /locus_tag="IVV98_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP7807527.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            4505..5713
                     /locus_tag="IVV98_001890"
     CDS             4505..5713
                     /locus_tag="IVV98_001890"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP7807528.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            5867..6322
                     /locus_tag="IVV98_001891"
     CDS             5867..6322
                     /locus_tag="IVV98_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807529.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            6684..6959
                     /locus_tag="IVV98_001892"
     CDS             6684..6959
                     /locus_tag="IVV98_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807530.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            6972..9050
                     /locus_tag="IVV98_001893"
     CDS             6972..9050
                     /locus_tag="IVV98_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7807531.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            9210..11096
                     /locus_tag="IVV98_001894"
     CDS             9210..11096
                     /locus_tag="IVV98_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7807532.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            11108..12055
                     /locus_tag="IVV98_001895"
     CDS             11108..12055
                     /locus_tag="IVV98_001895"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP7807533.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            12075..12602
                     /locus_tag="IVV98_001896"
     CDS             12075..12602
                     /locus_tag="IVV98_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7807534.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(12665..13318)
                     /locus_tag="IVV98_001897"
     CDS             complement(12665..13318)
                     /locus_tag="IVV98_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP7807535.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            13450..14292
                     /locus_tag="IVV98_001898"
     CDS             13450..14292
                     /locus_tag="IVV98_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7807536.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            14450..15346
                     /locus_tag="IVV98_001899"
     CDS             14450..15346
                     /locus_tag="IVV98_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7807537.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            15349..16062
                     /locus_tag="IVV98_001900"
     CDS             15349..16062
                     /locus_tag="IVV98_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP7807538.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            16082..16600
                     /gene="msrA"
                     /locus_tag="IVV98_001901"
     CDS             16082..16600
                     /gene="msrA"
                     /locus_tag="IVV98_001901"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7807539.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            16597..16824
                     /locus_tag="IVV98_001902"
     CDS             16597..16824
                     /locus_tag="IVV98_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP7807540.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            16976..17527
                     /gene="lepB"
                     /locus_tag="IVV98_001903"
     CDS             16976..17527
                     /gene="lepB"
                     /locus_tag="IVV98_001903"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7807541.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(17610..18152)
                     /locus_tag="IVV98_001904"
     CDS             complement(17610..18152)
                     /locus_tag="IVV98_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP7807542.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(18389..18787)
                     /locus_tag="IVV98_001905"
     CDS             complement(18389..18787)
                     /locus_tag="IVV98_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7807543.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         6578 a         3231 c         3832 g         5309 t
ORIGIN      
        1 ttatcttttc tagaatttgc ttactaatgg taaaataaaa ataagaagag gagggatgcg
       61 tatggaactt gattatcaag tagaagatgc gttgacgaaa gtgttttacg gagaaacgct
      121 agtcagtcag ctaagagaac tttccattga tcagccaatc ttatttttaa cgaatcagcg
      181 ctattatgat ttgtttgcag ataagatcaa cccgttattt gcaaatcaag caaacaatga
      241 ctggtatatt tgtgccaaca ctcaatgcaa tcatttaaca gaattaaaga acctgcttga
      301 tttcgtcaaa cgctatcccg aaaatcaatc catgtttatc atcggatttg gaaatgaagg
      361 gatcatggat ctggcaggtt tttttcaaaa acatacaacc cttgattcat cactatggat
      421 gatccctgta tcgatccgtt ctctaagccg agcattaaca ccgcagcgga cgattttgca
      481 gctaccaaat cgtgtagtgc tgcaaaccat caatctgcca gaacgcatcg tttatgatca
      541 aacaatcagc gagcggcagg tggacggaaa gcagattgac tttttgactt ttatctgttg
      601 cggaatgatt tgtgatcatc gttttttgca aaatctgtat aaaaactatc caaataaaaa
      661 gcaattaacg actcggccgt ttgccgggat gatcgaagaa atgatctatt tttatcaatt
      721 agaggcagaa aacctgtcaa attatggtaa actgtttgaa caagcttttt atctgaccga
      781 aaatggccat ctactttctg ctagtatgaa aaaattttta ggaatgatgt ttcatttcgt
      841 gtggaatctc caagcatatc cttttgattt ccaactaaaa aacttttttg tgtggctgga
      901 cttgcttggc tatccaatcc actggctgga acagatttca aagatggagt atttggaaaa
      961 agttcttttt ttggcagaaa aaagcaaaaa aatacttgtt ttagaaaaaa taggtataat
     1021 agacggatac caacatccaa acgaaaaaga attattgaga acaatgacgg tatttcaaca
     1081 aatcgtcagt gagataagag ggaattgaaa tgaatacaaa tagcgaaaaa atgttgcaag
     1141 ctttatcaga tgaagacttg tcacaagcac aaatcttttt agaaaaagca ttaaaagaag
     1201 acccagcaga tatattagct gaactaggcg aagaattgct ggctattggc tttttgatcg
     1261 aagcaaaaca gatttttgaa caactgatca accaataccc agaaaatgac ggactgaaca
     1321 tcccgttagc agaaattgca atcgaagata atgagatcga cttagctttt gaatacctgg
     1381 aaaaagtgga taagcaaagt gattactatc cgcaaagctt attggcgata gctgatttgt
     1441 accaagttat cggaatccct gaagtgagtg aagcaaaatt gaaagaagca gctgggttgc
     1501 ttcctgatga accattgatc cagtttgcgc tagctgaatt gtatttttca gttgatcgtt
     1561 tcaaagaggc agcagtggtt tatgaaacat tgttggcaag cgggataaat gaaatttcag
     1621 gaatctcgat gcaggaacgt ttaggacaat ccttaagtat gcaaggagaa ttcgaagcag
     1681 ctatcgtacc tttagaagaa gcactgaaag aagaaaggac agatgatcga ctgttccagc
     1741 tagcttttac gaatcttcaa ttgaaagaaa atcagcaggc aatcaactat ctggaagaac
     1801 ttcgagaagt taatccgcat tatcaatcgt tatatctata tctaggacaa gctcttcaag
     1861 aagaagaaat gattgaagaa gcacaaacag tgttagaaga aggaatcaaa gaaaatcctt
     1921 accaagtcga actttatcac ctggcctcgg aaaatgcttt ccgtctgcat gatagacagc
     1981 gagcagaaga acttttactg aaagctttag aagtaggaga caaacaagat gaaacattac
     2041 ttactttaag taatctttac ttggatgatg aaagatatga agatgtgata caagtgatca
     2101 atcagatgga agaaactgct aatccttatg cagaatggaa cctagcccat gcttataatg
     2161 aattagaaga ctttaccgtt gcagctgtac actatgaaca ggcttatcat gaactatcac
     2221 atgaaccaga tttcttgaaa gagtatgcct ttttcttaag agaagaaggg cagctgaaaa
     2281 gagcgcaaga attattgact tattatttaa cacttgaacc aggagatatg gaggcactgt
     2341 cattattaga tgacctaaca gagaggtgag aaaaatgcta attgatgtac gggaaaagaa
     2401 gaatttttta acgtggatgg tcaatcatgt atcttttagc cgaagagaag ttttttggat
     2461 cttgaattat cttgccaatc atgaagcgat tttaagcaat gtccactttg ttgaaggggc
     2521 gaattttgcg gatcgaggac tgcagatcag tgatctatct gttgaagggg aacccatgaa
     2581 attgtttttg cagggaaaag aatttacgga cacagaccag atttttcatg aaatccgttt
     2641 gaattggaaa aagcctttat atgtggaatg tatattcgaa aatgcttggc agacaagaga
     2701 atatctatct atcttagaag acaatccatt ttcttcttgg gattcttcag tcagtgaaga
     2761 agatactgaa ttaattgaac gatattttca agaaaaagaa gaagaggcaa aactaaaaat
     2821 gctttatgct caaatcgatc aagcactaga agatggagat agggatgctt ttttgaaatt
     2881 atctgatgaa gttaaccgaa agatcctttt gcagacacaa aagaaaagta accgggtaag
     2941 tgaacataac aattagttaa aaatagtata gtactaaaaa agacaaaggt cagctggatg
     3001 tggaatcttt cctcatagcc tatctttgtc ttttttctta tagttttttc agtaatcttg
     3061 tctgtggctt caaataagta aagccttgcc cttccacttc atgcacattg atgattgaaa
     3121 ggaaagcttt ttcgtcaatc tcgtggacga tcctcttagc ttcagttaat tcactagagc
     3181 taacgaccat atagatgatt ttttttgaat taccagagaa tgcgccttct ccagaaagga
     3241 aagtcacacc tctttgcaga ccggtcatca gtagtggtgc aatctcttcg cttttgttgg
     3301 agacgacaag tagacctttt gcagaatatc cgccatctaa gatcgaatca atcacacgac
     3361 tgaaaacata cgaaacaatc aacgtataca tcatacgttt caagtcgata taggttaatg
     3421 aagcaagtaa gacgatgata tcaaatgcca atagggaacg ccccatagtg atgccgtaat
     3481 tttgttctaa aatccgagcg ataatatcac tgccgcctgt tgttccaccc atgcggtaga
     3541 cgatcccgct tcctacacct gcaactaaac ccgcaagtag agaaacgatc agtagatcat
     3601 gctgtaaatt gatttctagt ggaacccttt gccagatcca taaaaagaat gacaaagaaa
     3661 gtgtacctag aacagtatag gccaaggaac gtttaccgag gatctttcct cctagtaaaa
     3721 tcaatgggat gttgattaat aaagtcgtat aagctggatc aataccaaat aaagctctta
     3781 agatcaaggt gatccctgag actccccctt ctgctaaatg attagcgatg ttcaagtaaa
     3841 caagaccaaa tgcataaata cttgttccta taatgataaa aagaacttct tttactgttt
     3901 ttcgtttgac catatgaatt ccagctttca attatgtatt ttcacagaat ttccatttag
     3961 aaattccttc ctaaatgtag catggaaatt cgattttctc aattgctctt atctaggatt
     4021 tgcgttaaag ttttggtaag atagttttgg agggaaaaag atggataaaa agcgttcttt
     4081 atacagtatg cagcaggaag tggatgaata tatccagcaa ttcaaggtgg ggtatttctc
     4141 tccattagct cagatggctc gattaactga agaagtaggt gaattggcaa gagaagtcaa
     4201 ccacacttat ggagaaaaaa gcaaaaaggc ttctgaacca gttaactcgg tagcagaaga
     4261 acttggtgat gttttattcg ttacgatgat catggctaat tcattgaata tcgacttaac
     4321 tgaagttttt gaaaaaaaca tggaaaaatt caatcaaaga gaccataatc gctttgagcg
     4381 taaggacgag taaacaagat gaagtggtcc tggccttgaa gactctgaaa cggacttgtc
     4441 aaacagtcac catgcaactg agtctttatc tcaggacaag aaacacgcag gaaaggttgg
     4501 aaaaatgaaa ttaaaacaat tacctctgga ataccaaaag gcaattccag ttctgaaaaa
     4561 attagagaat gcaggatatg aagcttattt tgtaggtgga agtgttcgtg atatcttgct
     4621 gaaccagcca atccatgatg tggatatcgc aacaagcgca tttccagaag aaatcaaaca
     4681 gctttttcca aaaacgatag atattgggat cgaacatgga actgtgttgg tattagaaaa
     4741 tgatgaacaa tatgagatca ccacatttcg gacggaatca acttatcagg actaccgtag
     4801 accagatcat gtcgaattcg ttcgttcgtt ggcagaagat ttgaaaagaa gagattttac
     4861 gatcaatgcg tttgctttga aagaagatgg agaaatcatc gatttgttcg atggtctgca
     4921 agatctagaa gaacagatct tgcgagctgt aggcaatcct catgagcggt tccatgaaga
     4981 tgccttacga atgatgcgcg ggttgcgttt tgtcagtcaa ctagggttca aattagagga
     5041 agaaaccttc tacgccatca aagaaaacca cgagctatta ggtaaaatat ctgtagaacg
     5101 tataaatgtg gaattcatca agatgctctt gggaaatgaa cgggccgcgg gaatccatgc
     5161 atttattgaa acagagtgct acatttgctg tcccggtttg aaagaagaag gcgaagcact
     5221 tttacgtttt gctgaattac catccgtccc attgaaagaa gagagccaag catgggcatt
     5281 attgatcagc caactggatc taaaagaaaa tgagattcgt tcctttttga aatcgtggaa
     5341 gtgttctaac caaatgatta aagacgttca agcacttgtc caaggactac gacaacgaga
     5401 aactggagct ttggaaccat tcgaattgta cttcttaggc aaaaaacatg cactgcaagt
     5461 agaagaattg atgatctatt ttgacgaaac acctcagatg gatgccgtag gagaatccta
     5521 tgatcgttta cctatcaagt cattaagcga attagcagta gatggtaaaa tcttgctaga
     5581 agaaactgga aaaaaacctg gtaagtgggt tagtgaagct ttgcaattag ctgaaaaagc
     5641 cgtcgtagaa caaagaataa aaaatgataa aaaacaggtt ttggattttt tatcgaaaga
     5701 aaaattgatt taaaaaacac tagactgtat ctgctcagct ttgttggcta cttaaagtgg
     5761 gcagatacgt cattagaaga aaaaacataa gatgtgacca cttacataaa tttgtgctaa
     5821 actgaggtag tacaagaata aattacatca taaaggagtc tttttaatga gtaaagaaat
     5881 gacagcgcta aaattttatt ttagaaatgg agaaacctgg acgatcaacc gccgtcatat
     5941 cggcgatctt tggatcaaac aaatcacaac aagttttgga cgaatcaatg gcagtgaatt
     6001 tgttgaaatc catccgtgtg ctggatttaa aatcgaaatc ttccatgaag gggacgcagt
     6061 tgcgacacat gatatcaacc taggcggact ggaaatgggc atgtttaatc gcgcattgaa
     6121 atacgaagat atcgagcgaa tggaaatcct ttaccgaaat ggcacacctg atcttgtgta
     6181 cttcccatat ctagataaag gaacagaagg attagacaat caatatcaat caacaaaaat
     6241 cagcgaaaaa acaggtaact tgtatatcgt gatcaatcca gatcaacgtg tagaagatgt
     6301 atacggggaa tttttcgaat aaatcgattt ttacgcaaaa atgaggctgt gaaagagatg
     6361 tgtcttatta ctactgatag gctgtctctt ccacaccgtt tattcagaat aagggactgt
     6421 gacaagattt ttgtcgcagc cccatttttt tgttgtgata aaagaacaag aaaggcagga
     6481 atgggaaagt aaacatcctt ttgtcagaaa cttttatctt tcttaagttt tacttgatat
     6541 ctgatactat ttggaataga atgaggcgtt gaaaaattta tggaaatttc taactagcaa
     6601 taaacgatga aacaatgaaa tatttttcat ccaaaaagaa ctttgctata atgatggaag
     6661 tttgtgtata ggagatctgg aaaatgagag agagttttga acaacaaaaa aaactgttgc
     6721 atgatcgcta tggcgccctt tcgatggatg accgccgtca aatactttgt aagttgcgta
     6781 aaagaaatat attgatgtat cgtcagttgg aacgtctgaa acatgatctg cttcgtttgg
     6841 agtcaaaacg tgtacagtgt gaattagagg ggaaccaaac acaggttgaa gtagtcgaaa
     6901 ccaaaatttt aaagaaaaaa gaacaatttt taaaaatgct tacacaaaat aaaaaataaa
     6961 ggggatggac gatggaattt gctgagttag ttattgtatt tgcagtaacg atcaccttat
     7021 cgaacatagc tagccgcatt ttgccaatga ttccagctcc actgatccaa attttccttg
     7081 gagtggtatt aggtctgaca gagtggggac aatcaatcga ttttgaacct gaattgttct
     7141 tagttatgat tattgcacca ttgttattta gagaaggaga aaaagcagat atttcttcga
     7201 ttctcaaaaa tttcgggaca attttgttct tggcatttgg aggagtcatt ttgacccttg
     7261 tcggggtagg tgcgacgtta tcattcctgt tgccaagtgt cccacttgct gcctgctttg
     7321 cttttggagc agcgttaggt ccgacagatg cggtagcagt cagttctctt tctggacgag
     7381 tgaatatccc taaaaaggcg atgcatattt tggaaggaga aggtcttttg aatgatgcat
     7441 ctggtgttac tgccttccag tttgctcttg gtgcgctgat caccggatct ttttcagcag
     7501 taaacgcggg gatgagtcta gtagtttcta gtattggggg agctttgatc ggctttttgc
     7561 ttgtctggtt caaacaaaaa ataattcatt tgatcgaaaa agcatcagca caagatgtca
     7621 cagggtatct gctgatcgaa cttttgcttc cttttctagc ctatgtattg gcagaggcat
     7681 ttgatgtatc tggaatcatt gctgcagtgg cagcaggtat tctccaagct tctggtttta
     7741 ggaaaatctc tgtgtttgat gcagaattgt cgagcttgtc ccacagtaca tggacaacta
     7801 ttgcttttac actgaatgca ttagtattta tatttttagg aatcgaattg acgcaagtgt
     7861 tctcgccagt atggggagac ggtttatatc caaacggtct tttattagcg attatcgtat
     7921 taatctctgt catgcttttt gtgatcagat tcatttctat cagtcttttt tatgtattca
     7981 aagatggcag taaaaagttc aaaaaacagt tgaacgagat cttgatctta acatttggcg
     8041 gtgtaaaggg aacagtcagt ttggctacga tttttatttt gccattttca atcaataata
     8101 tgatgtttta ccagcggtct ttgcttttgt ttctgacggc gggtgtcatc ttagtgactt
     8161 tggtcatagg gatcattgtc ttgcctatgc tgacggaaac agaggaagcg aaaagcacgg
     8221 atttgaatgc tttgatgatt ttagaagagg tcgttgaagt tttgcgaaaa gaaataaagg
     8281 aaattgatcg taatacaaaa gaatttttag ccactgaagc agtgatagaa aattatcaag
     8341 aacggatacg tgatctgtac ttggaagatt taaccgatga tgaaaagcaa gaagtacaag
     8401 aaatacaagc actgattttg tcgatcgaac gggatggatt ggatgaaagt tatcgttcgg
     8461 gcaagctttc ttctaatggt tatcgttttt actcccgttt tctttctcga ttcgaacatt
     8521 ctatcacaag ccagattttg tcttttatcg gcttttggtt cattgttgtc cgtaggttaa
     8581 tgcgaatcgt tctccatccg aaaatgtttt ggcaaagaag atatgctgat cgtcagacat
     8641 ttattagtga tgaagatatc caagaaatca gagagacata tcaaaaaaat actcagttga
     8701 ttattgaaag tttagataac ttgactgata tttatgatga aacgatggtt caatttttta
     8761 tccagcaacg caaacttgaa ggaataaaaa tgaactcggg gaatttgatt tcttcgtgga
     8821 tgatccagca agatagtctg tttacgaaaa aaatgctaag aggttattat cttgaaagaa
     8881 aaatcattga tgaatacgaa gttgctgaaa aaatcacgac gttttctgcg aacagctatc
     8941 gcaggaatat caatttgtta gaatcttata cgatgaacaa accatctgat aacttttctt
     9001 tccgatttgc gtttcgagca aagtcaaaaa aaacgagtcc aataaaataa aaaggtaaaa
     9061 attttcaagt tttataaaaa acaaaacata tcagaacagg atcgaatcgg tcctgttctt
     9121 tttttgagaa cacaaaaaga acaaatacca aaaaaatttt cctgaagttc actattttta
     9181 tgatacaata tccaagataa ggagggaaca tgttgaaaga attaaaagta actgacctca
     9241 aaaaaactta tggtgaaaaa gatttgtttg accagatttc ttttttggtc cacgaaaaag
     9301 accgtatcgg gttgattggg acgaacggga cgggtaaaac aagtctctta aatattattg
     9361 ccggtatcga tagcagcgac ggtgatcggc aaacagtgtt ttatccaact gattaccgta
     9421 ttggttatct ttctcaagca gctgaatttt ccgatgaatt aactgttctc caagcagtct
     9481 ttcaaggaaa cagccccttg atccaaactg ttcgagcata tgaggaagca ttgatcgaac
     9541 taggggaaaa cggagaagac cctgatgtgc aaaaacgtta tgctaaagca gaagaacaaa
     9601 tgaataaaga agatgcttgg actacagata ccaacgcaaa gattattttg caaaaattag
     9661 gaatcagtga attagataaa aaaatcagta ctttatcagg tggtcagaaa aaacgagtta
     9721 gtctggcgca agtgttgatt gatgaacccg atttactatt actagacgaa ccaacaaacc
     9781 atttagatta tgaagcgatc gagtggttgg aaaactattt gaaacaatac cgtggcgcac
     9841 tattgatggt tacccacgat cgttattttc tagatagagt agcaaaccga atcttcgaac
     9901 tttcatttgg aaaattatac gagtataaag gaaattatga agcttacgtc ttagaaaaag
     9961 cagaacgtga tcgtgtagaa gtagaacaag aagaaaagcg caagcggctt tataaacagg
    10021 aattagcttg gatgagggct ggcgtacagg cacgtggcac caagcagcaa gcacggatca
    10081 accgtttcga agatctaaag gagaacttgt accaagtaaa ccaagaagat gatttagagc
    10141 tgaacctagc gacacaacgt ttagggaaaa aagtactgga aatcaaagat ggcagttacc
    10201 gtataaatga ccaaacactg ctagaacatt tagatttatt gattcaatct cgggaaagac
    10261 taggtattac tggtaaaaat ggtgcgggaa aatcgacatt gcttaatatt ctagctggca
    10321 gaattcccct ggatagcggt acaatgtcta tcggtgaaac ggttcatctt gcgtattata
    10381 cacaagaaaa tgaagaaatg gcaccagata aacggatgat tgcttactta caagaagctg
    10441 ctgaagaagc aaaaacagca gatggcagtc aaatcggagt agcagaatta cttgaacgat
    10501 ttttatttcc aagatttatg catgggacac tgataggcaa actttcaggc ggagaaaaac
    10561 gccggttatt tttgttgaaa ctgctgattc agcaacctaa tgttttatta ttggatgaac
    10621 cgaccaatga tttggacata gcaacattga cgattttgga agattatttt agaagttttc
    10681 caggtgctgt gatcactgtt tcccatgacc gttatttctt ggacaaggta gcagataagt
    10741 tattagtatt ccaaggaaac ggaaaacaag aactttatta cggaaacatg tccagttatt
    10801 tactgaagca aaaagagacc cagcagcctg ctgaaaaagc gaaaccaaaa atacagagca
    10861 aggaacctgc tgaaaagaag aaattatctt acatggaaca aaaagaatgg gaaacgattg
    10921 aagatgagat tgcagaactt gaagaaaaaa tctcattgct ccaagaagag atgaatcatc
    10981 aaggagataa tttcactcga ttacaagaat tgcaaaacga cgtatctgaa acagaagcac
    11041 aacttgaaga aaaaatggca cggtgggaat acttgagtga atgggtagaa gattaggagg
    11101 aaaaaggatg gaacaagcgt atcttgactt aggaagaaaa ttgttggaag aagggcatcg
    11161 taaagaagac agaacaggca caggcacatt aagcttattc ggataccaaa tgcggtttga
    11221 tctgcaaaaa gggtttcctt tgttaacaac gaaacgagta ccttttggat tgatcaaaag
    11281 cgaattgctt tggtttttaa aaggagatac gaatatccgc tatctattac aaaataaaaa
    11341 ccatatttgg gatgaatggg catttgaacg ctacatcaaa agtccagact ataatggacc
    11401 agatatgact gattttggcc atagatgttt gacagatcct gaattcaatg aagaatataa
    11461 aaagcagagc aagctttttt gcgagaagat cctaaccgat gattcctttg ctgaaacata
    11521 cggcgatctt ggacacatct acggctatca atggcgtcac tgggaaacaa aagacggtgg
    11581 ctttatcgat caaatcaaac aagtgatcga agcaatcaaa aagactcctg attctagaag
    11641 attgatcgtt tctgcatgga atccggaaga tgttcctagc atggctttgc ctccttgtca
    11701 tacgatgttt caattttatg ttcaagaggg acggctaagc tgccaattgt atcaacgcag
    11761 tggggatgtg tttctaggcg ttccgttcaa cattgcaagt tatgcgttgc tgactcacct
    11821 aattgcacat gaaacaggtt tagcggttgg cgaatttgtt cacacattag gagatgctca
    11881 tctttatatc aatcatatcg aacaaatgaa agaacaattg agccgagaaa tacgcgcatt
    11941 tccgacttta gttttgaatc aggaaaagca gtcagtattt gattttgaga tggaagatat
    12001 ccaattagaa ggatatgacc cacatccggc gatcaaagct cctatcgctg tttagaatca
    12061 gaaaggatga gaaaatgtta gctgcaattt gggcacagga tgaaaacgga ttgattggaa
    12121 aagaagaccg tcttccttgg cgtttgccaa atgatctgaa attcttcaaa caaatgacag
    12181 aagcaaatac actagtgatg ggacgaaaaa cattcgaagg gatgggtagc cgtccgttgc
    12241 cgaatcgtca gacgattgtt ttgacgagag attcttccta taaagcagaa ggcgtgcatg
    12301 tcatgcatag tgtggaagac gtgcttgctc tggaaaaaga aacagacggt atctttttca
    12361 tcgctggagg gtcagctgtt tatcaagaat ttctgccatt ttgtacgata ttataccgta
    12421 cagtcatcca tcatgtattc gatggagatg cttattttcc acctgttgac tggtctgatt
    12481 ggtcactgat caatactagt caaggagaaa tggatgaaaa aaatcgttat ccgcatcaat
    12541 ttgaaacgta tcagcgtaat gagaatcctg taaaaagcgg gacaggcgaa ttgacgatat
    12601 aaaaaagcta tggatagact agctgttatt tagagctgtc ccatccatag ctttattttt
    12661 tttattaagt aaagaataaa acagagaagt acataaaacc tgcacctaac ataacaaaca
    12721 aatgccaaac aacatgcata tagcggatag aattcaagct ataaaagaat gcgcctatcg
    12781 tgtaagaaag cccgcctgct accatcaaaa taacaccagt cattccaaga gagtgataaa
    12841 gaggaacagc agccacgaca cagagccacc ccataaaaat atagatgatc gtagatactt
    12901 ttgatactct ctcccgttta tgcaacgtca acgctttata tataatgcca agaatcgcaa
    12961 acaaccagat taatacaaat aaagtccaac ctagccatcc tcggatactc agcaaacaaa
    13021 aaggagtata acttcctgca atcaaaagaa aaatcgaact atgatcgaat acttggaaca
    13081 ccttttttgc ttttgtaaaa atcaatgaat gaaacaaagt agacgttaaa aataaaagaa
    13141 tcatcatcga tccatagata gcataagaga caatatggag ggaggaatgc aagtgggcac
    13201 cttttactaa aagaaccact agtcccgcga tactcaatcc agtcccaatt ccatgggtga
    13261 ctgcattaaa cacttcattt aatatttcat acgttcgatt aaatttcgtt ttttccatga
    13321 aaacggctcc tttactaggt gtaattaatg aaaaatcatt atttgtctgt tatactaaaa
    13381 atagaaattg tcttacatgt agtttaacat gaataaggca tcttgttaaa gaaagagaga
    13441 gagaaaataa tgacaaatgt aaaaatcgta acagattctt catgtacgat ggaaaaaaat
    13501 gtacgcgatg ctttaggcat tcgtgtcatg ccgctatcca tcatgatcga cggaacagta
    13561 tatcccgatg atgaccaact agacggcgaa agatttatgg aaatgatggc gaaagcaaaa
    13621 aatctgccca aaacaagcca accaccaatt ggagaattca tctcgatgta tgatgagcta
    13681 ggagaagacg gcagtgaagt gatttcgatc catatgacaa aaggcttgag tggaacagta
    13741 gaagcagcaa gacaagccag taatctaaca aaaacgaaag taacggttat cgacagtgat
    13801 accactgacc aaggattatc ttttcaggta attcgagcag ctgaattagc aaaagaaggt
    13861 aaaacagtag agaaaatcct tgaagaagtc aaaaaagtac aagacaatac aaaattatac
    13921 atcggaatat ccacactaga taacttggta aaaggtggaa gaatcagccg aacaactggt
    13981 ttgctgtcta gtgttttgaa catacgcgtg gtgatgaatt tcgcccattc tgaattaatc
    14041 cctgtaacta aggggcgagg aaagaaaacg ttcgataaat ggtttaataa tttgaaaaat
    14101 gaactgaaag aattgccaaa tgtgcgacaa atcggtattt cacatgcgga tgcaaaagaa
    14161 ttggcgcaag aattcaaaga gggtttgcaa gaattattcc cggacatgca tatccctgta
    14221 ctgcatacga atccggttat cgctacgcat actggtaaag acgcgtttgc aatcatgtat
    14281 tatgtagatt agtcgaaaag aggataagcc ctcagcctga aaggcttgca gcttattctc
    14341 tttttcttta taaaattagg aaaataattg ttttcttttt tcataaagac tacctttttg
    14401 ataaaatttt tgataacatt agaaccaatc gaatacaaga ggtgaaaaaa tgaaattaac
    14461 gaaacgacat ttgatcctcg ttttgttccc attattaatt gcgatcatca tctatgcagg
    14521 tttagctgct tctataccga aagctggccc actaatgaaa ccagtaacta ctgtgagaga
    14581 agatccaaat aaaaaagaaa aacttcacta catagctatc ggagattcgc tgactgaagg
    14641 agtaggagat caaaccaagc aaggaggatt cgttcccctt gtcgcaaatg atctaaaaga
    14701 ccgttataat ttgaccgcgg ttgaaacaga aaactatggt gtaaatggtg aacgaagtga
    14761 ccagatctta aagcgagtaa aaacaaaaga agaaattcga aacaatatca aaacagctga
    14821 ttttatcaca ctgactgttg gcggtaatga tttgatgaaa gttatccaaa ataatttatt
    14881 cgggttaacg gtcaattcct ttaaaaagcc actgaaaaac tatcaggaaa atgtcacaga
    14941 actattggaa gaatttcgat ccctcaataa aaccgcacct atttacattt taggcatcta
    15001 caatccattt tatttgaact ttcctgagat cactgacatg cagacaattg ttaacaattg
    15061 gaacaaagga acagaaacgg tgacaaaaaa aatgccgaac tgctacttta tcccaatcaa
    15121 tgatttgctt tatcaaggat tgaatcagga agtaggtgtc acagaagaag gaacagatca
    15181 aacaactagc acgacagaaa atctaaatgg catcaaaaat aatgtgctct atgaagaaga
    15241 tcatttccat ccaaataatt taggttatca attgatggca aatgcagtga gagatcagct
    15301 gatcgagaca caaaaccaat ggttagagaa ggaggatgat caataaacat gaaaacaaga
    15361 tctgacgtat cttcaaacaa aacaaagaaa acaaattact ggaaattcgc cttccttatc
    15421 cttcttgggg tagtacttgg ttcgaccgta tttttaggca gccgtatttt tgctaatcgg
    15481 gaaccagaac tcccagaaat accagctctt acggaaagac aaggagatcc tgtcttaacg
    15541 atcaattcaa ataaagaaaa agtcaatcaa atcatcagct ttttccttag tgagtatcaa
    15601 aaagatagtg atattgaata taaattttat ttggaaaatg aagcactact caatggtact
    15661 ttcgaagtac taggttttcc tatcgatttc tatttatatt ttgatccgta tgtgatggaa
    15721 aacggaaatg tccaactaaa agctagaagt ctttctatcg gaacattgag tttgccaatc
    15781 aaagatgtga tgaatatgat caagagaaac tataaattac cagattggat cgaagtcaat
    15841 acagatgatc tgactatcat gcttaggttg gatcaattcc gaatgcaaaa cgggatgtat
    15901 attaaagcag ataaaatcga cttagtaaat gatgacattc ggtttagtct atatttgcca
    15961 aaagatacct ctgatgcttc aaacaactca aataccaaca aaactagcac cagcagtact
    16021 gaaagcaaga caaaagaaaa taaaaaatca tcggatgagt agtattagag ggggaatcat
    16081 aatggaacga gcaatatttg caggaggctg cttctggtgt atgatccagc ctttcgacac
    16141 gcttcctggt atccatacag tgatgtcagg atatactgga gggcatgtac cagatccgac
    16201 ttatgaacaa gtaaaaagcc aaacgactgg acatacagaa gcagtggaga ttatctatga
    16261 tccaacattg atttcatatg aacaattagt agaactttac tggcagcaaa ctgatccaac
    16321 tgacgctttc ggacaattcg aggatcgcgg tgacaattat cgcccggtga tcttttattt
    16381 gacagaagaa cagcggatca ttgctgaaaa aagtaagaaa cagttagctg aaagtggacg
    16441 tttcgaacag ccaatcgtta caaaaatcga accagcccaa ccattttatc tagcagaaga
    16501 agaccatcaa gagtattata aaaagcatcc tgaaaatttt aaaagaaacc atgcacgccg
    16561 ggctgccttt atcgaagaaa attggaggaa cgaagggtga atcgaagctt ttttcattat
    16621 ttaatgacac tgcgaggcgg tggcacacat gatgctttat ctgttttcgc tacagaagcc
    16681 ggtaaagaca tccaatttcc taagcacagc tctagctacg aagaaatttc taattatctg
    16741 gaactgaatg tcgactattt gccgtccatg gatatctttg acgaagcatg ggaaaaatat
    16801 ttagaaaata atcatgacat ataagagata gttttgtact ttatgatcaa aaaagttttt
    16861 tgtccaatag cctaattgaa agaattattt ttatttcagc tatctagtcg catttttttg
    16921 atatttttct tataataaag aaagaatgaa aaaaagaggg atggattgat agagattgac
    16981 aaaaaaacaa cgctatatta atcgcttctg gcttgtattc aaatacttac ttgtttctgt
    17041 attccttgcg ttcatgttgc ggggattttt attcatcccg gtaccagtgg aaggcaattc
    17101 aatggaaaac gtgttgaagc aaggtgatat ggttgtgatg gaaaaatttt cggagatcag
    17161 acgatttgat attgttgttt ttcaattagc agatggcacg atttatatca aacgagtaat
    17221 cggtcttcca ggagaaaatg tcagctacca aaatgatcaa ttgaagatca atgggaaagt
    17281 agttaaggaa ccttatctaa ctaaaaacct gaaatcagat catgcaaatg catcctatac
    17341 gacggacttt acactacaag agctaacggg acaatccaag cttccggaag ataattattt
    17401 tgtacttgga gataatcgaa gagtttcaaa agatagtcgt tcgtttggca cgatcaataa
    17461 aactgatatt ctaggtaaag caagatttgt ctattatcca cttgatgaaa taaaatggat
    17521 ccagtgagaa acaataaagc gtgcagtctg ttgagactgc acgctttatt gtttaatcca
    17581 aaatcagttt actaccttag tacgtaaaat caaacagctc gtttaaacac ttttctagcc
    17641 tctaaagttt tgataaatga ataaacaacc attatttgaa tagggatttg gatcatattc
    17701 ctgatgaatc tacctagaaa aattactttg aaatctgcac caaacaaaac agacatcagc
    17761 caagaattga taaaaaggct gactgggatc ataatcaata attgggcagc gatgacggaa
    17821 ggcaggttta tctttttatg atataaaaat aagccattaa taaatccacc aaggaaagcc
    17881 gtgataagaa aagcagcttg aaacgttcct gaaccaaata tcgtgaaatt taaagtgttc
    17941 gacaacattt caagcaaacc agcccagatc ggtccatata gataacccat aagcgccata
    18001 cttaaaaatc cgaatgtgat ttgaaaataa gcaggaccaa tcgctatctt gtataagatg
    18061 acatcaaggg ctaataaaag agcagaggtc gacaacaatc ttgcattcat ttcgggcaat
    18121 ctaaaaacgt cttttgcaat caaagtgttc aaaatattct ctcctttgtc agttaataat
    18181 aaaaggatac cataaaatca ccaatgtgtc atgacacatt ggtgatttac atacactggc
    18241 atctaacaat taaaaaaagg gtgagaagac tgcttttata aactgtaaaa aagagattgt
    18301 acgaataaaa aaaatagagg cggagaatac ttatcgtatc atccgccttt gtttttttgt
    18361 tataaaaaac gtcagattag ttatctgctt acatcttcat ccatacgggt tctaatgtat
    18421 ttccgtctag atcttggact tctaatgaaa acatttcttc ttcaggcatt cccatatcta
    18481 cttcgtggaa agtaccacca ttttcttttg caatttgagc aaattttttt acttcatccg
    18541 cattttcaac actaaacgaa atcaaagcac cacttgtttt tttattatca gctatttctt
    18601 tatcttttat aaatttttta taaaaatcat gagagagaag cattatccaa aaagtgtcat
    18661 cccataccat tgaaccagct tcttcagtag aaaattcttc atttttttta aaacccagct
    18721 tttcataaaa agcaacggaa cgattgacat cagcaacagg aaaattaaca aaaaccatac
    18781 tattcatttg tttcgtctcc tttctgtttt gttcgtctat catctcttat ttaggaaacg
    18841 ctgtcaaaaa tttagattca tatatagaaa ccaaaataaa aatttgcatc atcaaaaaag
    18901 tgaagatgtg atagaatgag gactggttca ctttcactta actaatagat
//
LOCUS       DACCVH010000053        18863 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.053, whole genome shotgun sequence.
ACCESSION   DACCVH010000053 DACCVH010000000
VERSION     DACCVH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.053"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(584..1150)
                     /locus_tag="IVV98_001906"
     CDS             complement(584..1150)
                     /locus_tag="IVV98_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7807544.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1150..2106)
                     /locus_tag="IVV98_001907"
     CDS             complement(1150..2106)
                     /locus_tag="IVV98_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP7807545.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2106..2762)
                     /locus_tag="IVV98_001908"
     CDS             complement(2106..2762)
                     /locus_tag="IVV98_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP7807546.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3132..5150
                     /locus_tag="IVV98_001909"
     CDS             3132..5150
                     /locus_tag="IVV98_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7807547.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5577..7991
                     /locus_tag="IVV98_001910"
     CDS             5577..7991
                     /locus_tag="IVV98_001910"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP7807548.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8339..9892
                     /locus_tag="IVV98_001911"
     CDS             8339..9892
                     /locus_tag="IVV98_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP7807549.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10273..12057)
                     /locus_tag="IVV98_001912"
     CDS             complement(10273..12057)
                     /locus_tag="IVV98_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7807550.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12072..13793)
                     /locus_tag="IVV98_001913"
     CDS             complement(12072..13793)
                     /locus_tag="IVV98_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7807551.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13893..14654
                     /locus_tag="IVV98_001914"
     CDS             13893..14654
                     /locus_tag="IVV98_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7807552.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15621..15889
                     /locus_tag="IVV98_001915"
                     /pseudo
     CDS             15621..15889
                     /locus_tag="IVV98_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16561..>18863
                     /locus_tag="IVV98_001916"
     CDS             16561..>18863
                     /locus_tag="IVV98_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807553.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
BASE COUNT         6202 a         3345 c         3794 g         5522 t
ORIGIN      
        1 tttttgcagt tacaggttgt ttattttcgg aaaaagctaa tatagctaag attgaaacat
       61 ccatctggaa tttatctttt ttactgcttt gatcataaaa gtctgcatat tcatcactga
      121 tattttttct aataaattct tccatcataa aaatcacctc aaaacgatta tacgaactta
      181 cgttcttgtt gtaaagcgat atttgagggg caaaaaaggg gcataatttg actgatatta
      241 agttagctat tgatatatga atgacataca aaaatataaa atcttttaaa aatgcttata
      301 tatcaatgtt tttgccattc ttttatatat ctgttatatg tcaaaaaaat gtgttcaatt
      361 tcaatttgta tttgaataaa gaggttgtga aaaagctgtc ctgcatcaag taataagaac
      421 agccaatcaa aaacagcttc tcatgttttt gatttggttg gacttattac cgcagatata
      481 agcttttgag caccgtgaat aaagaggtta tgaaatcaac gctctaacct gagtattaga
      541 gaaaaaaacg caaaacatat catttatgtt ttgcgttttt tatttatctt tttttctcaa
      601 tacaatataa aataggcggc tggttctttt ggttgataaa ccgataattc agcacattat
      661 atgtttcctg tggcagtttg gaacaaaaag aatcaaccat atccagttct ttttctccac
      721 cttcatgacc atagtagacg acaaggatca atcgtccgcg aggcacaagt cgtttcaata
      781 tttcttccat agctgtgcgt gtagtctctg gcatagtgat gattgcttta tcactttttg
      841 ggagataccc tagattgaaa atccctgctt tgagattttg ttgttcagct atcacttctc
      901 ctaacgtttc gtggccttgt agaaacaatg agacacgttc ttctaactga cgctgttcta
      961 gcctttcacg agtagcatcg attgcttgtt gctggatatc aaaactatag acatgaccag
     1021 tttttccgat gtgttctgct agaaaaaccg tatcgtggcc attgcccatc gttgcatcta
     1081 cgacgtgatc ccctggttgc aagatttctt gcagtaatgt atggctgaaa tgcaaagcag
     1141 tttgcaacat cagacgctca cctttttccg tacatcatat tttccttgga agctatctct
     1201 gcgaagaagt tcttcatcaa ttgcattcaa gacttcccat tttttcaagc tccacattgg
     1261 tccaatcaag gaatcccacg gcgcatcccc tgtcaaacga tggatgatga tctcttttgg
     1321 tatcatttcc agctggtcgc aaatgacatt gacatagtca ggacggctca ttaattgaag
     1381 gcgaccttca tgatagtccc gcaacattct cgttttgcgc atcagatgca tcaaatggag
     1441 cttgattcct tggatatctg aatctaaaat ggtgcgtctg acattttctt tcatcatttc
     1501 taaactttcg cctggtaatc cgttgatcaa atgcgtacaa acacggatat tatgtttgcg
     1561 taatttagcc acgccatcta aataagtttg ataatcatgt gctcggttga tcagttttga
     1621 agtttcttca aaagttgttt gcaatccaag ttctacccat aaatacatcc gctcgttcag
     1681 ttcagcaagg taatcaacta cttcatctgg cagacaatcc ggtcgtgtac cgactgataa
     1741 tcctacgaca cctggtaaat tgactacttg ctcaaatcgt tctttgatta tttcaactgg
     1801 cgcatgggtg tttgtaaaat tttggaaata aacgatgtat tgttggacat gaggccattt
     1861 ttgatgcatc atgtcgattt ctttctggaa ttggattgga agagggtctt caggtgcaac
     1921 gatcatgtct cccgaaccag atacactgca aaaagtacaa ccgccatggg caacagtccc
     1981 atctcgattc ggacagtcaa atcctccatc gatcggcacc ttgaaaattt tcccgccaaa
     2041 ctcatttcgt aaagcgtaat tccaagaatg atatctttta tttccttctg aataaggaaa
     2101 agtcattaaa agtccttctt tctgtaagag ttatctattt gttttctttt ttctctatac
     2161 actggataag tcaggcacag ccaagaaaga ctgagtaagt aaccgccgat gatatcagta
     2221 ggaaaatgaa cgcccagata aatgcggctt atcccgacac ttactataat aaacatcatc
     2281 agcaattgaa gcaatgtgcg taaggttctt ttttgaacaa aagctggaag cagaaatagt
     2341 aaagaaccgt aaagaatcat actgcctgct gcatgtccac tagggaaact gtaacttgtt
     2401 tcaactacta agtgcgccaa tgaaggacgc tctcgcatga aaaatagttt gatcaccggg
     2461 ttgatgattc cagcaattac aataaatcca gaaacgaacc aaaatgtttc tgcccttttt
     2521 ttcttatacc acatccataa agccgcacaa gcaaataaaa tgatgacggt aagaggatta
     2581 ccgaatttag tcataaagag ttggtagctg ttcagatcag gataagaagc tctgacaatg
     2641 cctgtaaacc actgatcgaa accagaaagc cacgacagat ggaactttac gatccagccc
     2701 aaaatgaaaa acaggacaag aaagaagcta ccagccacct gaaatgatgt tttatatttc
     2761 atacaattcc tcctttgaag caatgactta ttatagcatt tttggtccag cgaaaaaaac
     2821 ggtaaagaga taaaaccaat gtatgattcc tctttgaata accaatattc ttataaaaaa
     2881 aataactgta atcggaaaga cattttttgg taatgcaaat gaaatgttag ggaaataaaa
     2941 tcagtgtttt tcgaaatcct tttaaacaag aacgtagacg taggaagaac ttgaaaatga
     3001 acagaagttg ttcattacgg taaattacaa tatgattaca aaaaacaaca aagctcttaa
     3061 ataactttta ataaatatta agagaagtta taattattaa taatagataa attgaagttg
     3121 gaggatagaa gatggaaaac attgcaagaa aagaacggag acgtttagaa cagaccaaac
     3181 gttttcgaaa agcaaaacga ggggcagcaa tcgtgggaac tgcgatggta ggctgttctg
     3241 tcgctgcccc attagtacag ccggttcctg ttcaagcgga tgaaacacct gttcagttcg
     3301 gcgcaagaat caatacagcg gcatttatca cagaaattgc tacttatgct caaccaatcg
     3361 ctcaagccaa cgatctatat gcatcagtga tgatcgcaca agcagttgta gaaagcggtt
     3421 ggggcagtag tgcgttatct caagcacctt attataatct ttttgggata aaaggcagct
     3481 atcaaggaca aaccgtctac atggatacgc ttgaattttt aaataatcaa tgggtaaata
     3541 aaaaggagcc tttccgacaa tatccttctt ttgctgaatc tttcaatgac aatgcctatg
     3601 tacttagaaa tacttcattt ggcaacggtt attactatgc cggtacttgg aagagcaaca
     3661 cgaaatccta tacagatgcg acagcttgtt tgacagggcg ttatgcgact gatcctggtt
     3721 acgcaggcaa attaaataat atcatcgcaa cttacggatt gacccaatat gatacaccag
     3781 ctagcggaaa cgcaggcggt ggagcgacta caggtggcaa taatactgga agtgcaggta
     3841 gtactggcgg ttcaagcaat tctggtaata caaactcagg ttcagcaact tcgaccactt
     3901 atactgtcca atctggtgat tctgtttggg gaatctcaaa taaattcggt atcacaatgg
     3961 atcaattgat ccaatggaac aacatccaaa acaatttcat ttatccagga caaaaactga
     4021 caatcaaagg tagccaggaa aatggctctt cgacgaataa ttccggtaac aataccaatt
     4081 cttcaggaaa tgctggtaca tcaaacggag gacaaacaac tggtgcgaaa tacactgttc
     4141 aatctggtga ttctgtttgg aagatctcaa atgatcacgg aattacgatg gctcaattga
     4201 ttgaatggaa caatatcaag aacaatttcg tttatccagg acaacagcta atcgtatcaa
     4261 atggcggttc ttctaatgct ggagcaaata ctggctcaaa tactgggaat acaagtggct
     4321 ctagttcgtc cagctcaagt tcttctaata cagcttcagg aacgaaatat acagttaaag
     4381 ccggagactc tgtttggagc gtctcaaata aatacggaat tacgatggct cagctaatcc
     4441 aatggaacaa tatccaaaat aactttatct acccaggaca acaactgact gtttcaaaca
     4501 gtggatcaac aaacagcacg tcaggtaata caggttcgtc aaccaataca aataacagca
     4561 gttcagttaa tactggcagc agttcgtctc aaggcactta taccgtgaaa gcaggtgaat
     4621 ctgtttggag cgtggcaaat aaaaacggca tcacgatgga tcagttaatc gaatggaata
     4681 atatcaaaaa caacttcatt tatccaggac agcaattgat cgttaaaggt ggaacttcgg
     4741 caaatacaaa tacaggttca actacttctg cagcgaaacc aaatacaccg aatacgtctg
     4801 ctacgacaag tacatcatcc actggtaata cgatgtatac cgtgaaagcg ggcgagtcag
     4861 tttggagcgt agcgaacaaa catcatatca cgatggatca gttaatcgaa tggaataata
     4921 tcaaaaataa tttcatctat ccaggacagc aagtgattgt gaagaaaggt tcatctcaat
     4981 caacaaacca acaatcagtt actggttcga aaacctatac tgtgaaatct ggagaatctg
     5041 tttggagtgt tgctgacagt catggaatta caatggctca actaatcgaa tggaacaata
     5101 ttaagaacaa ctttatttat ccaggtcaaa cgttgattgt agctaaataa aatagctgtt
     5161 cgaagaaata acgattgaat tccacaaaaa tatttgttac tataaggcta cttaaatatg
     5221 acaacacttg aaaaggaagt agtaaaaaga ctgaagtttc agagagcgca tggctggtga
     5281 gaatgtgcac ggatgctttt gaactcgcct ttgagttgcc cttgctgaat acccgagtaa
     5341 gcaagcggcg gtgacggccg ttacaacgtt cgaggccttt tcactaaggt aaaattaggt
     5401 ggtaccgcgt agattacgtc ctataaaaag agcaatcttt ttataggatt tttttatttc
     5461 ttttgtgaag tttgagaaaa caaagcaaaa ggaaataaaa ataaacagat tctgccggtt
     5521 ttttcgttat atttataata gaaacaagtg ttttcaatag aacaggagga cagcaaatga
     5581 gttacaatca taaagaaatt gagaaaaaat ggcaaaaata ctgggcaaaa acgaatactt
     5641 tcaacaccca tgatgatcct gaaaagccaa aattttacgc actggatatg tttccctatc
     5701 catccggtca agggctacat gtagggcatc ctgaaggtta tacggcaacg gatatccttt
     5761 cacgtgtgaa aagaagtcaa ggatacaacg tgctgcatcc aatggggtgg gatgcattcg
     5821 gtctgcctgc tgaacaatat gcgctagata caggaaacga tccagctgag tttacccaaa
     5881 aaaatatcga aacattccga cgccaaatca attctttagg atttagttat gactggaatc
     5941 gcgaagtgaa tacaactgat ccggagtatt ataaatggac acaatggatc tttacgaagc
     6001 tttatgaaaa aggtctagct tatgaagcag aagtagcggt aaactgggta cctgaattag
     6061 gaacagttat ttcaaatgaa gaagtgatcg atgggaaaag tgaacgtggt ggctatgatg
     6121 tagtcagaaa accaatgcgc caatggatgc tgaaaatcac tgcttatgct gatcgcttat
     6181 tggatgatct agaattagtt gattggccag aaagcattaa agaaatgcaa agaaattgga
     6241 tcggtcgttc agtaggagca aatattgaat ttaaagtggc tggtacggat aaatcctata
     6301 ccgtatttac gacacgacca gatactctat tcggtgcaac ttactcggtt cttgcacctg
     6361 aactagatct tgttagagaa attacgaccc ctgaacaaaa agctgctgta gaagcttata
     6421 tcgaagagac agctaaaaaa tcagatctaa agagaacgga tcttgcaaaa gaaaaaacag
     6481 gagtatttac tggtgcttat gcaatcaatc cagttaatgg caaggaaatc ccaatctgga
     6541 tcgccgatta tgtattatct tcatacggca caggagccat catggctgtt ccagcacatg
     6601 atgaacgtga ctttgaattc gctcaaactt tcggactaga aattcttcca gttatcgaag
     6661 gtggagatgt tgaaaaagct gcttacacag aagatggtac gcacatcaac tctgaatttc
     6721 tagacggcat gaacaaacaa gaagcaatcg ataaaatgaa tgaatggcta gaagaaaatg
     6781 gcgtagggaa aaaagaagtc agctatcgct tacgtgactg gctattctcc cgtcaacgtt
     6841 actggggtga accaatccca atcatccatt gggaggacgg aacagtcaca gctgtcccag
     6901 aagaagagct accattacgg ttgcctaaga caaaaaacat caagccaagc ggtactggag
     6961 aatctccatt agcaaatatc gaggagtggg tcaatgtcgt tgatcctgta acaggtaaaa
     7021 aaggccgtcg cgaaacgaat acaatgccac aatgggcagg aagctcatgg tattacctgc
     7081 gttatatcga ccctcataac aaaaaagaac tagcagatta tgaaaagttg aagcgttggc
     7141 taccagttga catctacatt ggtggagcag aacatgcggt acttcattta ctatatgcac
     7201 gattctggca taaattctta tacgatatcg gtgttgttcc tacaaaagaa ccattccaaa
     7261 aactatacaa tcaaggaatg atcttaggcg aaaacaacga aaaaatgtca aaatctcgtg
     7321 gtaatgtagt caatcctgat gatgtggtcg aaacttacgg tgcagataca ctgcgcatgt
     7381 acgaaatgtt catggggcca ttagatgctt cgattgcttg gagcgaaaat ggcttagaag
     7441 gaagccgtaa attcttggat cgtgtatggc gtttgatcgt tgatgagaac aataaaatgc
     7501 gtgaccgtat cactacattg aatgatggca agcttgataa agtgtatcat caaacagtga
     7561 aaaaagtgac agaagactat gaaaatcttc atttcaatac agcaatctcc caattgatgg
     7621 tctttatcaa tgaagcctat aaagtggacg ctctgcctta tgaatatatc gaaggatttg
     7681 ttcaactact cgcaccgatt gctcctcaca tgggtgaaga actatgggca atccttggaa
     7741 atgatggtgg tatttcttac gcaccatggc caacatacga tgaagcagca cttgttgaag
     7801 acgaagtaga agttgttttc caagtaaacg gtaaagttcg tgcgaaaagc aatgttcccc
     7861 gagacttagg aaaagatgag ctagaaaaag cagcattagc caatgaaata gtgcaagaat
     7921 atattgaagg caaaacagtc agaaaagtta ttgcggtacc aaacaagtta gtcaatatcg
     7981 ttgctaatta attggctctt tgtcaataag gactgatgag ttgtgcaaaa tcaaatctgg
     8041 gccagaatga acttcattct gtctcagatt ttttgttatt tcaaattgat taattgattg
     8101 atcaaaaagg ttttgatttt catgttctca aacacgttca atgtcttttt cttctgaatg
     8161 gtcttgtaag agatctctgt aatcatcaaa tttttgtcta ttaatcttag tattttttga
     8221 tgtataaact acctgaaatt gagagtacat accaaattca taaatttttt attagtggga
     8281 ctagtgattg tatggatttt gacgcataat gaatgaagta tgagaaaagg agagacaaat
     8341 ggatcaagaa ctatttatta tcgaagtatt atcagctaaa caaaaaatta tcgagaaagc
     8401 gaaaaaaaga gcgaaaagaa taatgttcaa gcttttaagc ttagtatttt tctctggttt
     8461 gctttttttc ggagctgtat cgttcctata tcgccatatg agtgcagtag tccgttcagc
     8521 tgaagggatg caaaaattaa ataatttgta tcacttttcg tggggagttg gcggaataac
     8581 aattgttgtg cttattgttt ttcttctact tatttggctc cgttaccatc aattgtcgcg
     8641 tcatttcgat caatggctta gtcaaagagc acaacagttt ttacataata aaccaacttc
     8701 tcaagatgat gactatcttt attttgagaa gacttcgacg agtcaagctt ttcggataca
     8761 aaaaagtgat tgccagttat tgctgagatc acttgatgat ttacctatct acttaggcga
     8821 aagcaaatca aaattcggaa tgaacacatt ccatattttt ttactagaaa acgaacccag
     8881 atgggaaaaa agccagtctt cgcctggtgg atacctgaca actaagatga gtacattagt
     8941 cactggtttt ttcctcattc ttttagctgg aacaatctat tatgggagat acactcagcc
     9001 aaaaatgtct tctcatataa atgctgcttc tcacatgaca atgaactcaa ctaacgatac
     9061 gcatatacaa aagacaaatg aagggttgtt agctgatcct aagcaaaagg taaatttgac
     9121 aacacaaaag ataaatgatc tcaaacttga tacagagacg cactctctct atatgacaac
     9181 agatagtggt gctaattggg tatttgtgcc gattgattcg caatggttgc gttttggcga
     9241 atacaccctg acaacggggc tgattcctga aggttattgg atggacaaca catatgatat
     9301 ttccgccgat ttctcatggt ttatctattc ttctggggat gatgtacgtc tgctgacttc
     9361 aagagataat ggtaaaacat ggcaaacgtc tattatcacc caatcagttc agccgatacg
     9421 ttatcgaaaa gcggtatttt atggcaacga tggtctattt atctgtacat cagccagtgg
     9481 gatgtctgca gaaactttgt acatttacac tactatggat ggcggaatca cttggataaa
     9541 aagtggaagt acaatgatca atcagccagt acaaaatgtc agcttcgtta caacttcttt
     9601 aggttttgtt tcgacacgtg aaagtttgtt ttatacaaac aacggaggac gctcattcaa
     9661 agaatcagtt ctgtcgattc cggaaaacta tcagacaggg gggatagatc tttttcaatc
     9721 accaaatgaa gttactcaaa taagcgcgaa tacgttagag acaaaatttt atttgttgaa
     9781 aaaaggacca atcgatgcag ggaaaatgtt tgcctgcctc ttccgttcaa ctgataacgg
     9841 ggaaacatgg caattcgttc agcaactatc gcaagtagaa caaggagatt aaagaagaga
     9901 gattgtgagc ctgacgttca gcaccgagtc acaagaaaca aattcaaaaa acagcttctc
     9961 atatttgttg aatagtgtaa ctcgtgattc ggagttgaca agagcaacaa gaagcgattt
    10021 tgaagtatag cttctcgtat tttacaagat cgtgtcttat tgccgatagg ttgtctcttg
    10081 aacaccgttt attcgtaaaa agggattgtg acaagtcttt tgtcactact taccgaacga
    10141 aactgaagga gctatccaaa aagtatcatt agtattattc tttgtgtttc tagtggcacc
    10201 actagtacat ttaaaaaagc tatcgatcat ggactaatca tacatgatcg atagcttttt
    10261 agataatgtt tgttacgcta tctgaaattg actattataa agactggcat aaagcgttgg
    10321 tgattggagt agttcagaat gtgttccttt ttcgacgata tcgccattct tcattacaag
    10381 gatcatgtct gcattttcaa tcgttgacaa acggtgtgca atcacaaaac ttgtcctatc
    10441 ttttgtcaca gcttccattg cttgctgaat caatgcttct gttcgtgtat ctacgctaga
    10501 agttgcttca tctaaaataa cgacaggagg attcgctaga atgactcgag caattgtcaa
    10561 taattgttgc tgtccttgag ataacgtgcc gttttcgcta gaaatgatcg tatcatatcc
    10621 gtctggcagt gttcgaataa agtgatcaca ttgtgcgatt tcagccgctt cgataatttg
    10681 ttctcttgtg gcatccattt tcccgtaggc gatattatca gctaccgttc cttcaaacag
    10741 ccaggtattt tgtaaaacca tcccaaaaga acgacgtagt tctccacgtg aaagcttggt
    10801 aatatcaaga ccgtcgaatt cgatctttcc tttattcagt tcataaaaac gcatcagcag
    10861 attgactaaa gtcgtttttc ctgcaccagt tggaccaacg atcgctaccg tttgttttgg
    10921 ctttactgaa aaatcgactt gattcatcaa tattttatct gatgtgtaac caaactgtac
    10981 atttttgaaa gctatttttc ctttcggttg ttctaaaagt cttgcatctg gaaggtctgg
    11041 aatttcatct gtttcatcta atatctcaaa tatcctatcg attgctgcca ttgcggattg
    11101 gatcgagttg atcacataag aagcggtaga aattggttca gaaatctgat tgatgtactg
    11161 aagataagct tgtaagaagc cgatcgtcac accacctgat agaacaagca tagcaccgaa
    11221 taccgcactt atgatgaagg cgagttgatt aatgaaacga atggccggat agatagcaca
    11281 gttcataaat tgagcacgtt taaaagcgtt gtattgcttt ttatttactt cgtgtatagc
    11341 agcttctgca tgagcttgct gattgaatgt tttgaccact agattaccag ctaagatttc
    11401 ttccattcga ttatttaaaa cacccagttc atactgattc tgttcagaaa tctgtttgtt
    11461 tttgttcgca atcttagttg taacaattga actgccaacg atcagcaata agacgagcaa
    11521 agtaagcttg ctttcgatat aaaacagcat cagaccagca gcagctattg ttacgacaga
    11581 agtaaaaaat tgattgatac ctgtcaataa cacttgagaa agttgattga gaccggtagt
    11641 tgtccgacta atgatgtcac ctacttgatg attgtcaaaa aacgacatcg gtaatgtttt
    11701 gaattttttt gtgatttctt ttcgcaccct caatgtgatc ttttcgctta acgctgccat
    11761 tgtccgttcc tgaataaatg aagtgatgct gcttaagact gaacagccga tcagcaataa
    11821 gacagggaac aacaatgctt gtttgatatc actgaaagaa agctgtccaa tacctgtttt
    11881 tcttatttct gataagagat catcgatccc gattcccatg atcaagggca tggctacgac
    11941 taataggttc ccgaataaac tgcatagaaa caatccgtaa aaatatttat gttcaggttt
    12001 gatcattttc caaaaacgta tcaaagcacg cgtgttcaac gtttttttct tttccatcgt
    12061 atcccttctt tctatattcc ttgtgatttt gcaaactcct gataagtttg gcaattagac
    12121 agtagttctt catgagtacc ttgtccaacg atttttcctt catctaaaac aatgatgtta
    12181 tctgcttgtt ggattgtact gaggcgttga gcaacaatca cgagagtttt ctccgacatg
    12241 tgtttatgaa gggctgctct taatgctgca tctgttttat agtctaaagc ggagaaacta
    12301 tcatcgaata catagatctc tgctggtttg atcaacgctc gagcaataca tatccgctgt
    12361 ttctggcccc ctgaataatt agaaccgcct tgagcaacaa agctgtccaa tccgtcagga
    12421 agggtgtcca ctagttcttc taattgagcg atcttgatcg ctttagacaa ctcttctgtt
    12481 gaggcatatt catttcccat ctgcaagttg cttaaaattg tcccgctgaa taagaaagcc
    12541 ttctgaggga cataactgat gtgggagcgg atctgttctt gagtcatttg agtaagagga
    12601 ataccaccaa gggttacttt tcctatcgta gggtcactaa gtctcaagag aagtttcgcc
    12661 aaactacttt ttccagatcc ggtcccgcca acgatcgctg ttgtttttcc tttaggtatt
    12721 gtgaaatcaa tatcttctag aactggatca gagatttcag tatatttaaa tgtgacatgt
    12781 tcaaaagcag ctgcatttgt ctgatcaaag gttggttcag ctactgtttt gatcgtctct
    12841 tcctcaattt cgatctctgc ttgcagtatt tcttctatcc gtcgtaatga ggcaaacgat
    12901 ttagggataa tgaccaatac catagctgcg atcatcaagt aagcaagtgt cagcatagag
    12961 tattcgacta cagcagtcac gacaccgatt tgtaatgctc cttctgctac aagatttccg
    13021 ccaaaccaca aaatagaagc ataaacgatt cccatgagca aaaaagcaat tggagtgacc
    13081 caagcaaata ttcggttcac tttgatcatt tgattagcat agtcagcaaa gctcttattc
    13141 gttcgctttt cttcatatga ttgattatca aaggcacgga tcatattaat cccagtaaag
    13201 aattctctca atgtgatggt gatccgatcc atttttggct ggatactcaa agataaaggt
    13261 gcccctcgtt tcatcagtcg ataaacaatc catacataaa aaacaacaga gatcaatgta
    13321 acccatgtta gtaatagaga ataacgaaac atcatgagaa tggtgaaaac gcaaataacc
    13381 ggtgctggta agatcatttg gcaaaataaa acaatcattt gctggacatt atcgacatca
    13441 ttcgtcattc ttgtcaaaag agatccagaa ctaaaacgac tgatatcctt cattgacagc
    13501 tgttggaatt tacggaaata tttctcccgc gtttggaatc caaacctagc ggaagccaat
    13561 gctgaaaagt aactagaggc aactgcagcg attgttccta gaaacgctac aagcagcatt
    13621 tcaactccaa ttttttttat aactgaggct tcgccacttg ctatacctgt gtcgatcagc
    13681 tttgctacta attttggtac acctaatgta ccggcgattt ctaaacagat catcacaaag
    13741 gtaaggagag cgagtccttt gtttttctgt aagaatgttt ttaagataga catattattc
    13801 ctcctttttt cctgatactt ttcgattcta taccttcaag taacttgaag gtcaatagaa
    13861 aaaagaataa actgaaaaag aggtgagaaa aaatgaaaaa aatgtatacg attggccaag
    13921 tatcggaact atttgatttg ccaaaatcaa cgatccgcta ttgggatgaa caaggattaa
    13981 tccgttcaag tagacaagaa gagaatgatt atcgattgtt tgatatcgat gatattttta
    14041 tgctttatga tatcgttttt tatagaaaat tagatatacc gatcaaacag atgaagaatt
    14101 tatatggaaa aacattgacg gagttatatg agacacttga tgaaacagaa agaagaatcc
    14161 ataaagaact ggtggtgatg aaacaaaaac aaaaagagat aagggagcaa aaaaaacagt
    14221 tgaaattgat gatcgataca aacgaggaag aatttcctgt agaagagatc ccttttgact
    14281 gtatgatctc aacggagttt gaagatattg tggaaatcaa aaaatttcta cctaactatt
    14341 caagctttgg gatgatgagt atgccagctt ccagttcaca gacgatgtat ggatttttta
    14401 tcgaccctag tgaagtacat ttatttactc aagacgtgat ttgggagaaa aaagatacgg
    14461 ctgtttatcg tcgattctta ttgaaatccg agatgaacca tgcggaacgt aataatattt
    14521 tagaaatcag agaaagaatg tatgaaaaag gatggaaaac aggagaagtg atcggccagt
    14581 atctattgac gaatacggat gaaaacaata tcagaactga atattatcat gcatggatag
    14641 aaatgaaaaa ataggaaata tgtgtttaag ataactcgaa aatgatggtt gttttagtta
    14701 taaagaaaaa ttttctggtt cgattacggg tttaatgtgg gggattatta gtcgtggata
    14761 gatagaattt tagtttttta gaggaaatat gtctttaaaa atggaatggt tgcaattctt
    14821 agcgatatat acgatgtaat tgtcctctta aaaaagtatg gaaaaataat tgtattgggt
    14881 gttatgtata attcatggtg aactgagact aatgagaaga aaaattcata ttgttatgag
    14941 tgagattgta tcagatgaga atgataaatt aaataggtgc ataaaagcat tacacttaaa
    15001 atacattgtt gcttacatta ttacaatatg ttaataaggc aaaaataaat agatggattg
    15061 aataaacata ttttttaatc aaatagtccc tactgtgact ttcctcagct atcggtgata
    15121 ctaccgatag catttttttg cttataaaat aattataagt atttagagat ttttcttcta
    15181 acattcttca aacaagaaaa atcacaaagg ttattgttat ttttatatat tctttttaag
    15241 aatgattgtt tttttataga aattttaaaa aataaaacac gttattgatg gatagttagt
    15301 ttgttatttg gtaatattat agaagttgac tggtagtgat ttatttttcg tcgttttata
    15361 aaaatgttat tttttggaaa aattcacaaa tatgtaacga atgtttttct ggaatttgct
    15421 gtgttaaaaa gcagtatgac taatataaat actattgtca tttatgcaat tttttatgga
    15481 tagtaatttt agaggggaat caatgaagga agaatagaag ggaaaaatag ttgcaaatac
    15541 gccagttagc aaaaatagca atacatcttc aagctttaaa attcgagaga atcatcttgg
    15601 tagtggaatc aactacaaca aaaggattaa accaattaat agatagaatt accaatggaa
    15661 aaatagaaaa ggtagttatt ctatacaaaa gttgtttaat tcgcttcggt tatgaactta
    15721 gtgaaaccct ttgcaatata tggtacagaa tatagaaatt attgacatta cagaaaatga
    15781 tgaagattta atacagattg tcactatttg tagatacctt ttacaaggaa accgagccaa
    15841 taaagctaag aagatgatta aggagttgat ggaagacgat acaagttaag aaagtgaaac
    15901 tacgcccaaa taaagagcaa aaagagtaat tggacgtgga aaatgcaaga aatgaaccat
    15961 cgattcggtg gacagtttat tagtaatgac ggtttgagaa catccatgac gagaatgaag
    16021 gaacatccta aatgcgttta gttgaaccaa gtgccaaata atatggccaa ataagcgatc
    16081 agttatcgat gaatcccaag tattctaaac tatatattca ttttgatgct aagcattgat
    16141 atattttttt gggattgatg aaggttaacc aatacaggga ctcactgatg aaattctaga
    16201 gtctgacctt ggtatcaacg atttagtgat tgtttctaat ggaaaagtat aaaagtatat
    16261 aagtacatta acaaaataac tattagggtt acgctccagc ttgtgcaagg cactggcagg
    16321 aggaatcgtg aaatcataat tatggttaag ccacacggac aactaaaagt catacaaagc
    16381 tatcgaatca atcaacagaa gacaatcggc aatcattagc tttgtttaca gcttacattg
    16441 caacgcttga gttgaaccga aaatacgagg gaggtaacgc agccattttg agttggggaa
    16501 tctttttaga aaattatcgg gtaccttgtt gtttagtcaa aattataagg gggagtaata
    16561 gtgaggaaca aatttcataa actgttaagt atgtttctag ttatgcttat tgtgatcaat
    16621 caatttggga acataacggt tctagctgag tctttagcag aacagccaga gcgttcgctg
    16681 acgatcgaag ttgatcaaga ggaggctgct ttgggtgagc agttccagtt gcgagtcaga
    16741 ggaacaccag acctgctaaa tgcattggtc attgataaga gtgaggattt gattgaaggg
    16801 gaagtgaagc aactcaatga ttacgaacgt ctgattactt attcttccca gcattcaggt
    16861 aaatacgaat tgaccgcaag aagcggtgat attcaatcaa atacggtctc aatagaaatc
    16921 agtgtaccag aagaaagcac aagtgagtct tttaatgtac cagaagaaag cacaagtgaa
    16981 tcttttaata taccagaaga aagcttaagt gaatctttta atgaagccag atcatctgag
    17041 ccatctataa cgcaggaatc tcagattgaa agacaagagg agctcttgaa ttatgacatc
    17101 ggcatctctg ctgagcgccc cactttgccg agcaggcata cacaaacgtt aaagggatac
    17161 attcaaggag gcgctggcga tattcttgaa gaatatgggg agatggtcgt acgagttcct
    17221 agagcatcga ttggcttaat tgagttcatt agagtggagg tcgctgatga ttcaccttta
    17281 aagccactgg cattttacca agaaggcaca gacgttgttt ttccatttac ctttgattat
    17341 gaaggattaa atgaagccgc tcagtcgtat acattcagta tcacgtttga agttgctttc
    17401 tttcaatcag gcggtactga gccaaataat gactttcaag tgagtcttac ttatgctgag
    17461 cgagcagcaa acacggaatt ttcaattacg cctattcctt catcaagacc cattttttcg
    17521 aaattatact atggctctag agaaatcgac agccaaggaa atcttgggaa tctgctgatt
    17581 gacgggcaag acgtgaccaa cagtaataaa tttattttgc aggtaaatta tgaaggatca
    17641 cgaaaagacg gtgtagtggt taccgatgta ctaccgcaag gaacaacttt ggcaccgaat
    17701 ccgactacat ggagttccac tggaaataga gaacctattt caggtggggt tcggatcgca
    17761 gaagtaacga atccaggtga agcaaacgtt agaactcatt atgtttccga ggaatttgtg
    17821 gacaaagtat cttttaataa ggaaacgaat acacttgttg tggactttgg taatctagca
    17881 gagggtcaat cgtattttat tgaatatgct cttgaagtga ccgatgtcga cttgttcaat
    17941 gaaggaagac aagaggatgg gttttctcgg aatcgagcga gtatgaccta caataatcag
    18001 gtaatgagcc gagactaccg cttgagaatc cctgaaagta atcttccggc aatctcttta
    18061 agaaaaagtg tggacaaaaa tgttatcaat ctcaatgaaa atgaactaac gtatactctg
    18121 catgtctcga tgttttctgg aacaagaaat acgcttgtta ttgaagatgt tttggaagaa
    18181 ggcatggaat ttgtgtcatt tctatcagat attccctctt tcattgatgc cgaagtcaat
    18241 aatggaatag ttcgtttcag tgcgaataat acgattggtg gtccgacaag ttttaccctc
    18301 tcttttaagg tcaatgtaga ggcgtatgcg gtcggcgatc aaattttaaa ctttgcaacg
    18361 cttgtgaata gtgacaatcg attgaatacg agtactgtaa gaacaaggaa aatcgatggg
    18421 cgtattaaag taattaaaac tgatgagaat ggccaaaggc tggcaggagc aaaatttgaa
    18481 attttatcaa gcgattcaca agtgatacaa gaaggtataa cggcagaaaa cggagaattt
    18541 ttaagtgaac cgcttcctgt aggtagctat caagtccgag aaacagaagc accggaaggg
    18601 tatcttttag atgcgacggt acatgatgtt tttataaatg aatactccat agaagaagtg
    18661 acgttaacca ttgaaaacat ccttgatacg ggtggtgttg aactaattaa acatgctgaa
    18721 ggcagtggtg aagtccttca aggagctgtt tttgagttac agaaccgaga aggagaaacg
    18781 ctacaaaccg gtttaactac aggagaagat ggaaaactgg caattgacgg tttagcacca
    18841 ggagcatatc agctggtaga aac
//
LOCUS       DACCVH010000054        17818 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.054, whole genome shotgun sequence.
ACCESSION   DACCVH010000054 DACCVH010000000
VERSION     DACCVH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.054"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..135
                     /locus_tag="IVV98_001917"
     CDS             <1..135
                     /locus_tag="IVV98_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7807554.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVV98_001918"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVV98_001918"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP7807555.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="IVV98_001919"
     CDS             complement(2412..2663)
                     /locus_tag="IVV98_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP7807556.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="IVV98_001920"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="IVV98_001920"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP7807557.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="IVV98_001921"
     CDS             3613..3831
                     /locus_tag="IVV98_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807558.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="IVV98_001922"
     CDS             complement(4120..4632)
                     /locus_tag="IVV98_001922"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP7807559.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVV98_001923"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVV98_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP7807560.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7519)
                     /locus_tag="IVV98_001924"
     CDS             complement(7085..7519)
                     /locus_tag="IVV98_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP7807561.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="IVV98_001925"
     CDS             complement(7529..8317)
                     /locus_tag="IVV98_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7807562.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="IVV98_001926"
     CDS             complement(8314..9255)
                     /locus_tag="IVV98_001926"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP7807563.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="IVV98_001927"
     CDS             complement(9432..10019)
                     /locus_tag="IVV98_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP7807564.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVV98_001928"
     CDS             complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVV98_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP7807565.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="IVV98_001929"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="IVV98_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP7807566.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12936..13871)
                     /locus_tag="IVV98_001930"
     CDS             complement(12936..13871)
                     /locus_tag="IVV98_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7807567.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14057..15016
                     /locus_tag="IVV98_001931"
     CDS             14057..15016
                     /locus_tag="IVV98_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAP7807568.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(15102..16196)
                     /locus_tag="IVV98_001932"
     CDS             complement(15102..16196)
                     /locus_tag="IVV98_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7807569.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16385..17146
                     /locus_tag="IVV98_001933"
     CDS             16385..17146
                     /locus_tag="IVV98_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7807570.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17261..17701)
                     /gene="fabZ"
                     /locus_tag="IVV98_001934"
     CDS             complement(17261..17701)
                     /gene="fabZ"
                     /locus_tag="IVV98_001934"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP7807571.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
BASE COUNT         5139 a         3871 c         3110 g         5698 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag
    12901 gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat
    12961 tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct
    13021 ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt
    13081 tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc
    13141 ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact
    13201 agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa
    13261 gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct
    13321 ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga
    13381 acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct
    13441 ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca
    13501 tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt
    13561 tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca
    13621 ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg
    13681 ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca
    13741 ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa
    13801 ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc
    13861 caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata
    13921 atcaaagaat ctctactatg caatgttcat ttttataacc cgcgaattgt aaaattaagt
    13981 tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa
    14041 aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga caatgataga
    14101 atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg gacgtgctat
    14161 acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc ttgattattg
    14221 gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat tacctgctca
    14281 tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg tcattatcgg
    14341 gcgaaaagaa aggtctgttt catgcggtat gagaacactt tatcgtttat tttctaaagg
    14401 aatatttgat attgacacac taccgatgaa aggtaaaaga aaacccaatg gccatcagga
    14461 aaaacgggga aaacaacagt atcagcgctc aatccatgat cgacctgata attatcctga
    14521 tttcaattct gagtttggtc accttgaagg tgatacgatc gttggcattc atcataaaag
    14581 tgccgtcatt actttagttg aaagattatc taaagtcatt atcacgatta aacccaacgg
    14641 ccgtaaggca ttagatattg aaactgccct taatcaatgg ttttctcgct tccctaaaaa
    14701 cttctttaaa tctattacgt ttgactgtgg aaaagaattt tctaactgga aagccattag
    14761 taaccaacat gatattgata tatattttgc ggaccctgga acaccttctc aacgcccatt
    14821 aaacgagaat tctaacggga ttctgcgtcg taatggactg ccgaaatcaa tggattttag
    14881 aaaagtgaat cagacattta tttccagtgt cagcaatcaa cgtaatcata ttccaagaaa
    14941 atcattgaat tacagaacac caatcgaaat atttttgagc tatgtacaag aagcatttta
    15001 ttctagctta atttgacaaa tcataaccta taaaaaaaca aaataaaaaa gcagaaataa
    15061 ctggctattt ctagcggatt atttctgcaa taactaatta tctatttttt attttcaatt
    15121 aatttaaagc ttgaccatgg tttcaaaaag tcaaggagga ataattcgtc atcggagatt
    15181 cttcctacaa cattgacacg tccgtcgttt ttcatatcct tcaaggcgat ttgtgtttct
    15241 cctttgtatt gaccgtaccc ttcattgtca atcagtacat ccccatgatg catatctcgc
    15301 gtattatgag gcgggaaatc tttatctttg tagtatacac gagtcatcgt tgaacgaagg
    15361 atatattctg agcgatcccc tcgataacta tgaaggttat caaacaagca gattcgttcg
    15421 ttttctgtaa taccttcttc cgtatctact ttcaatgttg gataatccgc gttaaatgct
    15481 tctgccattt ctttcaattc ttcttcactt gcgtacgcat ttccaataga aatatcatca
    15541 atcaatcctg taaggattaa atgcttcact tgtgtcgcaa tttcaagatc tcggtggtct
    15601 tccagcgtgc acaagccatc ttgcgtaggc caagggccaa actcagcaga ttgcgaattg
    15661 acgaatgcca tcgtattcaa attatatttt ctgaattttt ctgaacaaaa aacaaagtgt
    15721 tcgtatccta aaccagagta tcgatgagga taaaaattat gagaacctaa taaattatcc
    15781 gtgtttggcg aataactcat gatgttgtca acgtaattcg tgcccgaact catattgatc
    15841 tcgattttga taccaaaagg attgcgcgtc atttttgctt cttctgctcc tgtgaatccg
    15901 atatctaagc ggaccccgta ggcacccatc ttatggaaaa aagataagtc atcgtaagaa
    15961 atctccaact gttcaaataa cgctggattg atatcaacca ttacttccat gcctaggcta
    16021 ttcgcgtaat caactacttc tttaaattct gaaagaactt tttctttatc atcattgatc
    16081 tgcagcaaac tggtaaaaac ccgtttatac ccatacttat gagctaaatc caagtacgct
    16141 ttgtcctttt caaatgttga ccgttctgga taaatcgaga ttcctaattt tcccatatta
    16201 ccatttcctc ctgcatcttt tcgtttttgt atccacttac attatagcaa acacaaagta
    16261 aatggtctac accttttctt tttcttttaa aataaatgat aaattccaat aatttaagta
    16321 ggtattttcc ctctattttg ttatcattaa agataacaaa atagtaaatt ggaaaggaac
    16381 agttatgaag aaaaataaag ttattttaag tattagttta gcagcagcat tgctgtttgc
    16441 tgctggttgt tctgcaaaca acacgacttc ttctagttcg tctacagaaa gttcaaaaag
    16501 tacatctact gcggaaagca cgactgccag tagcgtcgat ttgaacgcat tggaattacc
    16561 acaattgacg aaagatgtcg ccgaaaatga agatctggtc gaaatggtga cgaataaagg
    16621 cacaatcaaa atcaaattat ttcccgaaca cgcaccaaaa gcggttgaaa actttatgac
    16681 acatgcaaaa gacggttact acaacggact gactttccat cgcgtcatca aagatttcat
    16741 gatccaaggt ggcgatccta aaggcgatgg cactggaggg gaaagcattt ggggagaagg
    16801 atttgaaaca gagatcaaca accaccttta taatataaga ggtgcgttat ctatggctcg
    16861 ctcacaagat cctaacagta acggcagcca gttctttatc gttcaaaata cagatgatat
    16921 gcatgatggt cttttaaaag acgactatcc tcaagcaatc atcgacgctt ataaaaacgg
    16981 cggttatcct tcactagatg gccattatac tgtcttcggc caagtgattg aaggaatgga
    17041 tgtcgtggat gctattgcaa atatcgaaac agatagttca gacaaaccaa aagaagaagt
    17101 aaaaatcgat aaaatcaata tactgcaaga agcaaaacaa aaataaaaaa ataacgtctg
    17161 aatcctgcat agatgacaac gtatgctagg attcaggcgt cttcttttta cataaaaagc
    17221 aagtaagctt ccttttgttt tgctatatca ggttttatag tcaagcattt tggttgacga
    17281 tgaacgtgaa ctcgcactca cagacttttt tatcatctac atatgctgca gataacgctg
    17341 taccgactga tcccttcatt ttggtgattt caaaatgaca tttcagcaca tctcctggaa
    17401 caactttttg acggaatttg gccttattga tcccaccgat ataagctctt tttcctagaa
    17461 actcttctga ttttaggata agtatcgaac ctgcttgtgc cagtgtttct agaatcaacg
    17521 cacccggcat cactggattg tcaggaaagt gaccttggaa aaaatcttca ttgattgtta
    17581 cattttttgt cgcaacgatc ttttttcctg gttctaaagt atctacataa tcaatataac
    17641 aaataggata acgattagga atcaattcca ttacttcagt agcagataat acgtaagaca
    17701 taattaaact ccttctttca ggcaattgcc attttcatta ctttgactat caaagtatca
    17761 tattcctaaa tatttagcaa tcttttttta atttaagaaa aaatagtttg acaatcaa
//
LOCUS       DACCVH010000055        17589 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.055, whole genome shotgun sequence.
ACCESSION   DACCVH010000055 DACCVH010000000
VERSION     DACCVH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.055"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..199)
                     /locus_tag="IVV98_001935"
     CDS             complement(<1..199)
                     /locus_tag="IVV98_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807572.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
     gene            complement(362..1996)
                     /locus_tag="IVV98_001936"
     CDS             complement(362..1996)
                     /locus_tag="IVV98_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807573.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2000..3373)
                     /locus_tag="IVV98_001937"
     CDS             complement(2000..3373)
                     /locus_tag="IVV98_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807574.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3389..3628)
                     /locus_tag="IVV98_001938"
     CDS             complement(3389..3628)
                     /locus_tag="IVV98_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807575.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(3810..6485)
                     /locus_tag="IVV98_001939"
     CDS             complement(3810..6485)
                     /locus_tag="IVV98_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAP7807576.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6668..7591)
                     /locus_tag="IVV98_001940"
     CDS             complement(6668..7591)
                     /locus_tag="IVV98_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807577.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            complement(8114..9118)
                     /locus_tag="IVV98_001941"
     CDS             complement(8114..9118)
                     /locus_tag="IVV98_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP7807578.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
     gene            complement(9189..9485)
                     /locus_tag="IVV98_001942"
     CDS             complement(9189..9485)
                     /locus_tag="IVV98_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807579.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(9478..9771)
                     /locus_tag="IVV98_001943"
     CDS             complement(9478..9771)
                     /locus_tag="IVV98_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807580.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(9917..10468)
                     /locus_tag="IVV98_001944"
     CDS             complement(9917..10468)
                     /locus_tag="IVV98_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAP7807581.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(10642..10941)
                     /locus_tag="IVV98_001945"
     CDS             complement(10642..10941)
                     /locus_tag="IVV98_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAP7807582.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(10968..11276)
                     /locus_tag="IVV98_001946"
     CDS             complement(10968..11276)
                     /locus_tag="IVV98_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP7807583.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(11393..12352)
                     /locus_tag="IVV98_001947"
     CDS             complement(11393..12352)
                     /locus_tag="IVV98_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7807584.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            12496..13272
                     /locus_tag="IVV98_001948"
     CDS             12496..13272
                     /locus_tag="IVV98_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807585.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            complement(13370..14017)
                     /locus_tag="IVV98_001949"
     CDS             complement(13370..14017)
                     /locus_tag="IVV98_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7807586.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(14017..14847)
                     /locus_tag="IVV98_001950"
     CDS             complement(14017..14847)
                     /locus_tag="IVV98_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7807587.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            complement(14847..15596)
                     /locus_tag="IVV98_001951"
     CDS             complement(14847..15596)
                     /locus_tag="IVV98_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807588.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            complement(15610..16074)
                     /locus_tag="IVV98_001952"
     CDS             complement(15610..16074)
                     /locus_tag="IVV98_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807589.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            complement(16124..16585)
                     /locus_tag="IVV98_001953"
     CDS             complement(16124..16585)
                     /locus_tag="IVV98_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP7807590.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            complement(16567..17541)
                     /locus_tag="IVV98_001954"
     CDS             complement(16567..17541)
                     /locus_tag="IVV98_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7807591.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
BASE COUNT         5379 a         3369 c         2577 g         6264 t
ORIGIN      
        1 tataataaac atttccttga ggtttccttt taatcccctt cggaaaatca ccttttgtaa
       61 aatcgctctt aaggaaatca tctaaattac cagttctggt ctttttacct ccagtattcc
      121 ctgatttttt aggtggtaca tgttctttag taagttcagt gtatttttca cataaaatac
      181 acttacccat ctttttcata tctatcccca ctctttttaa ttcttatata caattatatt
      241 tcaaatattc attaataaat atccctattt atgataagga cctccctaac tacttctcta
      301 acgatttcaa atcgctagag aagcgttagc gcccctctaa cgttgtttga tataacctag
      361 actagatcgt taacgtaaag ggtgttttta acacaaaaat agccgtatcc tttgttttgg
      421 atacggctat ttgatattgc tcattcaatt gttgtaccac ggcatgcgtg aatttcatcg
      481 taatttccaa catctcctta tggttaggat caaaggttat tttctctata aaggtacgat
      541 acaaggcttt gatttgcttc ttctcactct gggcaagaaa acgatccaaa ctagtcaata
      601 tccgttggac atctttgact tgaatcggct ctccttgttg aaagatccct aagatttcat
      661 tttctcgaat gtgcaactgt cgtcgttttt cagtcaattc gtctaagcgg tcttttaaca
      721 tcggaaacaa ttcaggacta tcttccaaag cagcttccca tttttcaatt ttagtcttca
      781 attcttcctt tcgttccagt aacaccacga gttcttgttc caatggttgg ctttgtcgca
      841 ctatttcttc atttaacgct gccaccaatc ggggaagaac ttctggtagc tgaacgatct
      901 cctttaatcg gtcggcgaca aatgtttccg cttgttcggc acgaatcgaa ttggcatgac
      961 acacacttgc tcctttattc cgaaagactg aacaagaata atatcgaatc cgtttctttg
     1021 tgccatcctt tagggtattt gtgacattac tcgctgccat cggtgcgcca cattctggac
     1081 aacgtaacaa gcctgtcaat acattttcac ctgtatggtt ccatttgggt tgttttcctt
     1141 ctaaagcaag gcgttcttgt actttttgat aatcttcttc cgaaataatc ggttcatggg
     1201 ttcctttcac taaaatcggt ctcggattct tccccttccg tcgtttggtt tcccaattga
     1261 tgtagcgcgc atattctaaa taccctgcat aaattttatt gcgtaagata tctttgactg
     1321 ccgtggtaga aaaagcattc tttttgactg tttgatatcc ttgacgattc aaaaaattgg
     1381 caatcgctcg ataccctgct ccgcctaaat attttgcata gatcagacga acaattttcg
     1441 cctcttctgg ttcaatgacc aattgttttt gaccattcgt gtcaatacca ctgacatagc
     1501 ctaaacgtcg gcctcctgca taacgctttt tatctttcac taagctttgc attgacattt
     1561 gaacattctc cgcaatttgg ttgcgttcaa attcaccgaa actcccaagg agttgtaaca
     1621 tcaatttacc tgtcgaagtg gtcacgtcaa attgttccga gatcgaatgt aatcctacgt
     1681 catatcgcaa taattcctcg actgtttgta agacatctaa catattgcgt ccgagacggg
     1741 tcaatttcca aatcactagt agatcaaaac gatggttccg agcatcgttc atcattcgtt
     1801 gataggcgaa ccgatttttt gtggatttcc cactgattcc ttcatcggca taaacttcta
     1861 ccacttcata gcccatccgt tcggcaaact gtcgtccatt ttgttcttgt gcttgaatac
     1921 tatgtccttc taaagcttgt tcttgtgtac tcacgcgaat atacaatgcg actcgtttgg
     1981 tttgtatcat ttccatagat cattcgttcc tttctaaaat attttgtgtc agttgtcgga
     2041 agtaaatccc acaaactgtt ttatcctttg ttacctcaat ccgacaaaca tagtcacata
     2101 ataattgtcg actagagagg tcttttagtt gaagccattc tttcactttt gcttcacact
     2161 gttggagtga aagaaacgaa gaagtagaca tcggcttttg aagagcttgc agttgttgct
     2221 tgagttcttc cagtgaacaa ttgccctctt caaatgcctt aatccattgt gcttcttgtt
     2281 tcttttgttg gattactttg cgtttttcat cttttcgctt ttcggctaat tgttgcgtta
     2341 attgggcaat caaggcttga tagacgcctt cgtattgaaa aaaagcctgt atcttttcca
     2401 atacttctga ctcaaccctt tctgcccgaa gaaaaattcc ttggcagctt cggtcggtac
     2461 aatgataata atgaagcgtc ttcgtcttct ttgtattcca ttgatacttc gaactcagat
     2521 gacgaccaca gaagggacac cgaatttttt gacgtaataa gtacagatac gtatcttttt
     2581 tagctgtaca ccttgattgg cgaatctctt gggcttgtaa aaaggttgct ttcgagagaa
     2641 tcggttcaaa ggttcctaga tacttcccca aagatcctcc tttgatttcg ccatagtaca
     2701 atggattttt taggatacta taaatatgat agggctgaaa aggacgttcg cggaagaaaa
     2761 gcttttgttg cgtcaatcgt tgacaaagct ttttgtagcc atattttttg gtcaaataaa
     2821 gttgaaaaat atagcgaaca atccttgctt cgtgtacttc ttgttggatt ttcccattca
     2881 ctaaacgata cccatatggt accgcagaag acaaatattg ccgttgttgc tttttatagg
     2941 aaagtccggc acgaacattc tcaataatga cgtttcgttg ttgttctgca aaagtgaaca
     3001 ataattgcac aaatagttta ttcgttgacg cgtgtgagaa agaagcagga agaggttcag
     3061 aaatcgaata cacttgaacc tgatgttgtt ggcacaactc aataaattct aaggctattt
     3121 tggcttgacg tgccaatcga tcataacgcc aaacatagat caccccctct tcttctgacg
     3181 cacaaaccca agctctaagc tgtcgaaaag ctggacgctc cgctttttcc cctgattctc
     3241 ctttgtctga aaatcgttgg ggaatttgtt catatttctc taaaacatac tctttcactg
     3301 catcatattg agcgtcatta ctaattttcg cttcttcata aacagacgtt cgatcataac
     3361 aagccacacg catgcttgat tcccctctct atgaatgaac taaataccat tttttcacga
     3421 ctcttctatt gaacgaacgt tgcacaaagt gattttctaa atatccttcg ttcttcaacg
     3481 cttgaagagt acccccgata gatccagcag atacccctct tatttcgaaa tccaagtaaa
     3541 ttggttttgt aaaaaaggct tgatttgaaa aatgttcttg aatatacaga agaacctctg
     3601 cttttagtgt cattttattt ttagtcatta gaattttcct ttctttcatg tttgattgaa
     3661 tgaagtaaat gaagcataga tcaagcttca tttacttccg tttgggtttg ctcgctatca
     3721 tacagataag taatcagttg ttttgctaaa tcaataagaa atatttccat aacatggtgc
     3781 ctcactttca tactttggtt tattctaaat tacaatcgaa aatacgattt gagtgaagaa
     3841 ggtaatagaa tctcgtatgt tggaagaact tgacgattca tgtgaatacg tttcgttctt
     3901 ctcccttttt ctgcacacat attacccgaa tcaagcaatt gcctaaaaag ataggttaga
     3961 tcctttactt gaaattctcg ccttaacaag tcctcaaacg ggataggaaa aatatttacc
     4021 ttaatatccc catttttttg aattgatact tttccccaaa tcgtactggg cgtatgtttg
     4081 ttgtcactgt ttgttaaaaa tttatggcta ttcatcacca acaatgtttt cactcggtca
     4141 aataccgttt gctcacttcc taaactagta tctacaatta actgttcgta cgaattaata
     4201 agcaccgtct gtatatgctc taatcgtaaa ggatagccca gtatatcttg aattaggagg
     4261 gctccactat aaatcaaagc tagattatta ccaatgcgtt gcttcaaaga atgttcaggt
     4321 aaaacagccc atagtttttt ttgagcttcg acaaaagttg cttcaatttt tgtaatccct
     4381 tgttcaaaga gtttcaaaag aaataacttt ataccccaac caaaagtatt agaagaaaga
     4441 cttttaactt tctctgcgtg attcgcatcc tttgtaaact tgatatcaga aaattcgata
     4501 tatcgaactt tcaaaccagt taatttctca ttgaaataat tttccaaacg ctcttcagaa
     4561 gaggtaaggg tcaaaacaga aaaagtctct tgtggcataa gctgacaatt agaatctaat
     4621 cttagccttt cttctcctga agctaattga tagatcaacg agctaaagtt attttgagtt
     4681 gctgctccta actcatctag tattagtgga acacctccct gattgtttga tgctagcttt
     4741 ataatggctt tattggtagc attcatattt ctaagaaccg tagttggatt tccaaataaa
     4801 gaggcaataa agtgtaacgt agtggtttta cccgttgtgc tcttgccctg taggttaatt
     4861 agtaaactca aaaaagtatt agccttcgta acgtttaaat agcctaacac aatagaagca
     4921 ataccaatcg accaagcaag ttctaagttc gttcctaaaa catacttatg aaccaatgcg
     4981 tcaaattccg cttctgtacc attagttgtt aattggtagc atgagttttt agttaataca
     5041 gaaggaattt cacgtccaaa agaatcttgt aactgaaaaa tcattgcttc attttctttt
     5101 ttccagccaa gagattcatg ttcaaaaaag attggagcat tctcccgttg aatctgtaaa
     5161 aagtcaacga cttcagcttc tcttctagct ttaatgatta agccatgttt tgctaattgt
     5221 ttaaaattat tagtttgtaa acatccacct tctatttcta tttcatccca acaatgatcg
     5281 acataatagg caagaacaag tgtaatgact ttttgttcga tatttttgcg tatttgctta
     5341 ataaacatcg gacaagcaac tttttcttct tgaccttctt tcaccaaaaa tactccttct
     5401 tgattcagtt taaactggtc aaaataatat tcttgattgg attctaatga ttctacagaa
     5461 ggatttacag gttttggcaa cggatatttt tttacaaagt cttgaatatc tttattttta
     5521 tccgaagcat gcagacaatg aaatcgaatc ttattatcag ccgtaacaga caaacaagaa
     5581 ccattagaat tattcgtgtg ttttcttaat ggacattcgt caaatataag taaggtaact
     5641 cctttatgat cgccctcttt tatggtataa gttaattcag gatagtgagc taaccattgt
     5701 ttatagtctg cttgaataaa aggtaacact tctctaaaag atggatggct ttttactcta
     5761 gaggttgaca tcatggaatt ttcttcaact atctgttcaa gaattttaaa acaattactt
     5821 ctatctatgt tatcgggaat agaaaggaaa ctagataaac gatgcggacg ctcttttgtg
     5881 gactttcctt tgaccgctgg tgtaccaact aatttgcata atcttgaagg attataaaca
     5941 gaagtatcaa tatcaacttc atcttctact ccaaatcttc ggtgaagtaa ttgaagaaaa
     6001 ttctgaatag taagaatcgt ctcgtgatta tttggttgtt catttatggg aagaaaaata
     6061 tggtagccat tcccactatc aacttttaca aatgattcta ttctcttttc tttcaaataa
     6121 cgttctactt gttccataac attttctgcc tttttctttt cgctatctgt tgcacttccc
     6181 tctttccttt tagggtcaat atcaataaat acaaaccgaa ttttttcaat atcattgtct
     6241 ctcacagaat gctttttttg tgtaatcacc tcttgtttaa taggattata agttatgttt
     6301 actgtacctt cagacaattt ctgtttttct aaatagttaa taattgcttg agaatctgca
     6361 gtagaaaaaa tatgagaaac ggttttcttg tttaatgtag aaaaagttct caaattaaca
     6421 taagaaatcc ccagtgtatt taacagttgt aaatgcttct gaattgaagt gtgattcatt
     6481 ttcattaatt accactcact ttctaaaaaa tttttatttg tatgactaca ttacctccaa
     6541 cctctcataa tttcatgatc ttcagttcta caaaaatata tcccactcaa aatcttgaca
     6601 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
     6661 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
     6721 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
     6781 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
     6841 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
     6901 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
     6961 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
     7021 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
     7081 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
     7141 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
     7201 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
     7261 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
     7321 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
     7381 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
     7441 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
     7501 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
     7561 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     7621 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     7681 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     7741 cctttatcga ctttatcctt tttttatatt aaattttttc accggtagac agggagagaa
     7801 agaataaact aaaaagccct taattcttaa tgttttcacc tccttaccgt tcctaccgct
     7861 aaaatttaat ataactaaat tctataacat tagaagaaat tttaaatacc tttgataaaa
     7921 aatattgatg ttttttctct cattgtttac aaactagata gcttatgtat tcttattaaa
     7981 aataatagat atttcgaaca tcatcactct catctactta atttcgcatt tttactttat
     8041 aaaaaaactg attctaagaa aattaaataa tttttctcaa aatcagtttt tctttgataa
     8101 ataatatttt caattattta atcatttgaa aattgttagt cattccaata cgttgagaaa
     8161 ttcttccatc tgtataaaca cggaattgtt ttccaccagc cattgttgta tttccattat
     8221 catccgttac aatattaatt gaatagtagc ttccattttc atcttgcatt agatctttca
     8281 tatattcatt tgtgctaatt aaattagtat ttgatgcatt tttatcagga gaatcataca
     8341 accataaagc tttattattt agtacagttt ctttagcagc ttcccaactt gaaattgctg
     8401 agctacttgt agattgtgtc gttgtagttg ttgcttgttg agtagattct tctactactg
     8461 gagtttgagg agtttgtcca ttcacaatat caatgaaacc ttgttttaac tgttggttct
     8521 gagtttcatt gaagtacatg tagtttttat cattgccttg attttgttgc gttaaataaa
     8581 ctttaggttg tccattttga aagccaaaga aatatacatg ctgccctaaa tattctccag
     8641 tttctacatc agaataaact gctactaaat tgaaatctgc atgaccagtt ccatcttctg
     8701 accattgtac ggtaactggt gcttcattga ttgccatttt ccaatttcca tcaataactg
     8761 cacttggtaa aggcgtacca tacagactta cattgttctg aggattgtag cttttatatt
     8821 cttgacctaa tgtctttccc cattgtggga caaaaattgc tagttgagta gatttctcac
     8881 tatcccacaa agtattttta acctcttcag aagaagattc aatgattgaa ctttcacttg
     8941 tacttgcttc cacagattgt ttcatttctg ttgtagtttg ttcagttgat tgcgttttac
     9001 tttttttagc ctcaattgtt gtatcagttt ctacagtctc tttagtcctc gtattctcag
     9061 atgtacaacc agtgaataaa atccccattc caattagtaa taacaaccat tttttcattt
     9121 tatttccccc tttcaatttc tccctcgcgt acttatttta tcagtcaatt aatctcaatg
     9181 gtgttcattt agttaatcct ttcccaagaa tgtcgatagc cagcatgaca acgatctctt
     9241 ccttgagggc tttcagatgg attaaaacta gtagaaattt cccttccaca tcctctacag
     9301 cgataagttc tcattatttt tgggctatta gtattatttt tcttagttag agctatgagt
     9361 ccaactatga ttaccccaac tgtcttaatt acttttcctt tatctatatt cggatgcgca
     9421 agcatatatt tatataacca atatccaccg taaattaaac cacctaatac aatcagctta
     9481 gccatgtact cgtctccttt ctttttgttt aattactttt tgaatccatc ttgcagagaa
     9541 accataaact tctgtcaatt gacggatatc tacagttttt tcctgttcta tcatgttttc
     9601 gattcttttt ctaactaact cacgatcgta cattttcatt ggaaaagaaa tctgttgccc
     9661 tcgaaaagca agataaaatt gatagagcaa ttctgaatcc agttccattt cctcaaaaaa
     9721 gtcattcata cttttataag agttactcaa acaagtttca tcaatctcca tctacacacc
     9781 ccctgttatt ttttacataa tgaaaatagc atattactgg gtacattgat aattcatata
     9841 acatgtatca tcacatgtat ttttaaagtc aaaaagcatg taaaactact tataagtaac
     9901 ataagaaaat aaaatgttat ttttcttgaa ataataattg actatctgcc aattgccatt
     9961 cattacgaac atgaatactt agtgggtggg ataacttacc ttctgcattt atcaatactt
    10021 tggtcatctt tttttgtttc gcactcaatt gatcgtaaat ggtcttcgct tgttcataag
    10081 ccacttgact cgtcgctgta atcgaaccac aagcaaaaat aatggtgttg attttctttt
    10141 ctgtgaaaac agttgttaat atttccaaag attgttcatc atttccacga ggaaataccc
    10201 gaggactttt cgcttttgta tacgaaaaaa gattcacagc aataaaacca gtaaatccta
    10261 attgtcggat attcttttcg attaataaca tactcaaatc attcgtaaat ggttctgtat
    10321 ctgttggacg aatagtaatg actaccgcta atttatcttc cgcttctttt cctttgatcg
    10381 cccattgtcg tttgaaaaca tagcgatggg tatgatgagg atctcgccaa acttctgttt
    10441 gtgtggtcac taattctttt tcaatcatct ctttttctcc tatgctaatt tttgttcaag
    10501 caattcaatc accattgccg ttataagtgt caatactagt tgaaaatatt tcatattctt
    10561 tctccttttt tcttcagaat ttgatgaatc gctgtaagga tatcttctaa acatttcgca
    10621 atcattctca aataatcgat cttattcatt cgttcctcca atctgactcc aaaccaatcg
    10681 tccttctacc agtaacccac gaacaaattc tcgctggctg gtaatatctg taatgaaata
    10741 aactacatag tcttttccat cttctggtgc gcaataaata taaagatgtg tcatcactaa
    10801 acgtggtaga gtaacatctt caggaagcat acccatttca atttcctctt tttccatcgt
    10861 aacggattca tagccccact cttcaggagt agtgactagc tgtgcacact tttccagtac
    10921 ttcgatagcc gtttctaaca agtcctttcg ttcctttctt ttagatatca gtattcttct
    10981 ggtaataaca tcgtttgata ctcacccgaa tcaatgaccc atattttttg agacactgat
    11041 ttcaaacgaa gcttaggtga aatcagatac tcttttcttg cttctggttc ttcttgacga
    11101 tgaaccaact tttgatttcc tttttccgta gaaaattcaa agatttgaag atagtctaaa
    11161 tgaaattgct tttgaacgtt ttgatcgatt agattccaac ataaagcttg taattccacc
    11221 ggcaaactgt ccattactcc ctttgtgaca taacgttgtc ctttattttg aaacatttct
    11281 tttccctcct ttgccataaa aatagcccaa tcttctatta aagaagattg ggcttcatgg
    11341 atataatata tatttgatat tcaatttgat tcattttata ctatctgatt tgtcaaatta
    11401 agctagacaa tatgtcttta tctatgcagc tcaaaaatac ttccaatggt gttcgataat
    11461 ttaatgattt tcttggaata tggtttcttt tcgaggcaac ggattgaata aaggtttcat
    11521 ccgtgtccct aaagtccatt gttttaggta agccatctcg tctaagcaag ccgtttgagt
    11581 gctcatttag ccctctttgc gaaggtgttc ctggatctgc gaaaaagatg gcaatatcgt
    11641 tcgagttact tatagatcgc cagttggaaa attcttttcc acaatcaaat gtcatggatt
    11701 taaacaagtg tttaggcatg gatttgaacc aatcatttaa cctgttttcg atatcttcgg
    11761 ctcgtctgcc tgtcggtttc aaagtaataa taaccttgga taaacactca accaatgtaa
    11821 taacagcgct cttgtgttta actcccacaa tggtgtcgac ttcgagatga ccaaattctt
    11881 tagtcaggtg tggatagaga ctgttccgtt catgaatcgt tctgcgaaag gcctgttttc
    11941 cacgcttttc ttgatgatta ttcggtttac gtttcccctt cataggtaac gactgtgtgt
    12001 caaaaaggcc ttttttaaac atccgataga gtgtacgaac agaacaatca attggaaact
    12061 cgccacggcc gataatcaca tcgggtgacc atccttgagc taccttttct tgaacatatg
    12121 ttgattgttc atcagataaa acggttgaac gtcgtccaca acgagattta ttttgtttgt
    12181 attgacggta ataatctagc actttttttc cttgtttgag aaacgaataa acattataaa
    12241 tggtttgtct agagcgattt aaactttgtg cgacaagagc gacaggtttc tcgatattga
    12301 aataagactc tatgattact agttcgtctg ttgtaagatg ggtgtaagtc atttgtactc
    12361 actccttatt aattctttgg tcggaactat tttgagtgta gcacaaatga tctttttagt
    12421 tgtctagctt aattttacaa tcgacgtttt aataaattgt gatataatga agtataactt
    12481 tttagggagt gtactatgaa ttttcaagat aatagaccat tatatttaca agtagaagct
    12541 tctatacgta acgatattcg tgaaaaaaaa tatcttccag gagagcaatt acctacagaa
    12601 gaagaattat gtaaaattta tggagtaagt aagattacca ttcgaaaagc ttttaaactt
    12661 ttagcagaaa gtggaacagt tgaacgatta agggggaaag ggacctttgt aactcaaaaa
    12721 aaagaaagtt taaaattagc tggagttcat ggatttagcg attctctttc tacccgagga
    12781 cataaaatta gatatactgt tttacattct aaaattataa aggctgatga gtttttagct
    12841 aataaattac aaatcaatgt aactgataga gtttacaata ttaaacgttt aatgtgggaa
    12901 gacggtgccc cgatgggaat tgataatttt ttcgcatcag aagaaaaatt tccaacttta
    12961 tttgaaaaag gtagccaata tacttcatta tataaacttc tagaagatga ctatgatgtc
    13021 aaagctacga gctctattat ggaaataaac ggtttatctg caacacctga gctttccgac
    13081 ttattgcaat gtatagtagg agatccgcta tttattttag aaaaggttgg caaagataaa
    13141 aataatcaac catttcatta ttctcaatcc acagttcgtt gtgatagaat tagttatgtt
    13201 attgaagtca cagaaaatat cactttagat acggtgcata aaaatgattc agatcctaaa
    13261 gtaatagatt gatattaaaa gaaatcatac ccaaagcaat caattttgat tagatttggg
    13321 catgattttt atttttacta atattctcta aatacatcaa aaaacttatt tatattccaa
    13381 atttcacctg tacttcttgt cgcagatatt taatatcgta aataacatca tctgctagac
    13441 ttacatcttg agaaaaacgt ttatctttaa ttgcaagaac cttcatattt gctcttttac
    13501 cagcttttat accattataa gaatcttcta tcaccagaca ttcttcaact ggaattctga
    13561 gctgttctga agctttaagg aatatagtag gattaggttt actttctggc aaatctcttc
    13621 cgctaattaa acaatcaaaa tatgactcta ttttacaagt ggtaacaact tcatttatag
    13681 tatccattgg actggaagaa gcaattgcca tttttatttt tttctttttt aaccattcaa
    13741 gctgttcaat tagtatatta ggaaaaatat ccaagtaatc aatcttttgc gatttccaat
    13801 atttagtaaa ttttcccttc aattctaaac tgttacatcc ctcattgtac ttttctatat
    13861 catcaaaaat acttgctgta gttccaatct ttttttgata agaatacaaa ggatagctta
    13921 aattttcttg ttttaaaaaa ttaaataccc acttttgata cataatctcg ctatcaatta
    13981 aaactccgtc catatcaaaa attagagcct taatcattat aagataccta ttatacttaa
    14041 aacaaaccct gccaaaatac aacctaataa gagcatattt gtactaacat ttttcttaat
    14101 caatttatat attcccaaag tacatacaag tggtaataat ccaggaataa tggaatcaag
    14161 taagtcttgt aaaacaagtt ctgttccccc tgtagtgaat tttaaagggg tgacaattgg
    14221 caccatgcta gccaccattc cacctactac agccaaacca atgatagaag caaattgcat
    14281 tactcgatcc ataagacctt cttgatacaa tttagtaagg tatttattgc cagactcata
    14341 tcctaattta ccgccgtaaa aaacagctaa aatagaaggt atagcaaaaa ggccaacagc
    14401 taaaatcggt cctaaaatac taccttgctt agcaaaagac aatccaatcc caaatgtaat
    14461 aattcttaaa gtaccttgga aaaatgaatc accaattcca gcaaaaggac ccattaaact
    14521 ggttttaatc atggagatag attcagtatt aaagtttcct tcttctgctt gagcattttg
    14581 ttcttccata gaagcacaaa gtcccataat aaatgaagtc atttgaggcg tacagttaaa
    14641 aaatgccata tgacgagtat aagcttctct ttttttctct tcatcatttt tataaacttt
    14701 atttaaaatt ggcgccatcc catacataaa tcccatatgc atttgtcttt cataattcca
    14761 cgaacacatg attgtccatg aacgaagaca catcttatta agatcttttt ttgtgattaa
    14821 acgttttttt tctgtactat tttccattaa ccatgcgcct cttctctttt tccatattta
    14881 acttgatcca ttacaaaggc aatcagagct gcaaaaattg tcacgccaat tagtgaaaga
    14941 cctgaatagg caacaataaa gaatccaaaa ataaagtaag gatataattt tttactcaac
    15001 attgtgctta atagcattgc aaaccctaat gcggaaagca tatttccaga gacagtcaag
    15061 gcgtctgtaa tcatttctgg aattttatct actaaatctg ccacaacgtc agcaccaaaa
    15121 tatactgtta aaaagattgg aataaagtaa acaaaagcat taaaaataaa tgaccaataa
    15181 atatgaataa tttgagcttt tctaaattta ttattttcaa tggctttatc tgcagcatgt
    15241 ccaaattgag caattatcat gcgcatgata atactcataa attcaccagc tacagccact
    15301 gggatagcta ttgttaaggc tgtttctgta ctactattag ttaaaattgc aaaagcagtg
    15361 gcaataatac taccaagttg catattagga ggtccagccg ccccaattga gacgaatccc
    15421 atagaaatta attctaaaga tgccccaaga acaatccctg tatgcaagtc acctagcaca
    15481 agtccggcaa gtgtactcaa aattagtggt ctaccaatat tttgtcgacc aattaacctg
    15541 gagtcaataa cagctaccac accaactaaa cctaataaaa tggcttttaa taacatttat
    15601 tttcccccct tacttactaa aatctacatt ttcaatactt gaagatggga cttgttgcac
    15661 aaatattttc acttcttgat caagaatttt ttttgtggct tctaattctt caggagttaa
    15721 aaagactgcc tttccatatt gtttggactc gcttttctta gacacaccgc caaaattaat
    15781 ttctttaatt tctggtaaat tttgaactaa ttcaaaagct tccttaggtc ctttaattaa
    15841 aatcatgtaa ttatcatttg gggatgtttc cataatccct ttaacatcac taattttaac
    15901 aatgtctaat ttgcaatcag caggtttagc aattgtcaaa gccatcacag acattggatc
    15961 tcctggaact ttgttatcag ccacaataat atggttaata tcatactgtt tagtccaaga
    16021 aaatattact tgtccatgaa gtaatctgtg gtctacacgc actaatttaa tcattctatt
    16081 tcctccttca atttttaaaa tttatagaat agaaattgcc accttaactg acatctttta
    16141 aaagcgaatt aatatgaacc atactttttt gagagttatt cagtaattcc ttaaaatcta
    16201 tttcttctat agatttacca gctgactggg ccattaataa ctccagtaaa agaggtaaat
    16261 taatcccagc aataatttga attctattgt tgttcaactg tttaatagaa acattattag
    16321 gtgttcctcc aattaaatcc gttaaaataa ttagaggttg caaatgatgc tgactaatta
    16381 tttctttcat actctcctca aaatcatctg gactagtatt ttctttaaat ggaacagcac
    16441 taatacctgt ggcgtcattc attaaaatta attttgttgc ctttaaataa ccctcacaaa
    16501 gggtagaatg tgttgtaatc acaatgtgaa ataattgatt tgccatcttt tgcaacctcc
    16561 tattaattaa tatttcattt gccacatata gcgtctaaca tctaaggaat ggcctctttc
    16621 aaaagcaatc gcttctacca tttggcgaat aacaacgcca ctaagtacag ctgcaatata
    16681 ttctttcgct acactatcta tagattctaa gtcaaaatca gcttggtcta aaaccattaa
    16741 tttattactg aattttttag tgaagtcttc tacccgttga tctaaaaatc ttgtatctcc
    16801 aatacttttc actaagatga atggtacatc ataatcagtg atttcaaaag gaccatggaa
    16861 aaattcccca gaatgaatag cattagaatt aatccattgc atttccatga accagcaagc
    16921 tgctgtggag taaatttctc cgtaattgat accgctacca attgtgtaaa taattttatc
    16981 tcgtttttgg tttttacccc attctttagc agttatttca aatttgctct tttcagcaat
    17041 aacaagatca tttaacttat caaattcatt caagcaagtt tcccattttt tagagccatc
    17101 taaaacaagt aaaatattaa ataataaacc ataaagaatt cctttattta aatcactagc
    17161 atcaacatct ttaccccaat catagtgaac aggatattca gctgcttccc atagaggaga
    17221 tccttcttca ttagataaac aaatagtcat tgctccaaat tctcttgctt tttttgttgc
    17281 ttctacagtt tctggtgttg tgccagaatg ggaacaagtg ataactaaag aattttcaga
    17341 taatcctttt ggtatagcat agttaaattc gttagcagta taaacatgac aaggtacagt
    17401 taattcttta tcaaatagat attgaccagc cattaaaacg gcttgtgaac ccccacatgc
    17461 tgtaaaatat acatgatcaa ttgtcttttc ctttaacgct gccattgctg tttcaatctg
    17521 ttctttgtgt agttgtctca tttctttatc cctcactcta ataagtatta taaagtcata
    17581 taactttac
//
LOCUS       DACCVH010000056        17311 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.056, whole genome shotgun sequence.
ACCESSION   DACCVH010000056 DACCVH010000000
VERSION     DACCVH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.056"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(72..617)
                     /locus_tag="IVV98_001955"
     CDS             complement(72..617)
                     /locus_tag="IVV98_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7807592.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(629..1321)
                     /locus_tag="IVV98_001956"
     CDS             complement(629..1321)
                     /locus_tag="IVV98_001956"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP7807593.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1340..1624)
                     /locus_tag="IVV98_001957"
     CDS             complement(1340..1624)
                     /locus_tag="IVV98_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807594.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1637..2200)
                     /locus_tag="IVV98_001958"
     CDS             complement(1637..2200)
                     /locus_tag="IVV98_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP7807595.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2428..3090
                     /locus_tag="IVV98_001959"
     CDS             2428..3090
                     /locus_tag="IVV98_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP7807596.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3214..4410
                     /locus_tag="IVV98_001960"
     CDS             3214..4410
                     /locus_tag="IVV98_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP7807597.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4511..5887)
                     /locus_tag="IVV98_001961"
     CDS             complement(4511..5887)
                     /locus_tag="IVV98_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7807598.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5924..6790)
                     /locus_tag="IVV98_001962"
     CDS             complement(5924..6790)
                     /locus_tag="IVV98_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP7807599.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6879..7904)
                     /locus_tag="IVV98_001963"
     CDS             complement(6879..7904)
                     /locus_tag="IVV98_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7807600.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7922..8596)
                     /locus_tag="IVV98_001964"
     CDS             complement(7922..8596)
                     /locus_tag="IVV98_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7807601.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8780..9673)
                     /locus_tag="IVV98_001965"
     CDS             complement(8780..9673)
                     /locus_tag="IVV98_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7807602.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9747..11444)
                     /locus_tag="IVV98_001966"
     CDS             complement(9747..11444)
                     /locus_tag="IVV98_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7807603.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11437..12750)
                     /locus_tag="IVV98_001967"
     CDS             complement(11437..12750)
                     /locus_tag="IVV98_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7807604.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12750..16787)
                     /locus_tag="IVV98_001968"
     CDS             complement(12750..16787)
                     /locus_tag="IVV98_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP7807605.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16800..17258)
                     /locus_tag="IVV98_001969"
     CDS             complement(16800..17258)
                     /locus_tag="IVV98_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7807606.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4843 a         3893 c         3014 g         5561 t
ORIGIN      
        1 acaaagtcgt ttgttttatg ctcttctttt attattttgt gctttttatt ttatcaaatc
       61 actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat
      121 tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag tttgtatcct
      181 agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa
      241 taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg
      301 gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa
      361 ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat
      421 aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca
      481 aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt
      541 cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc
      601 gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca
      661 tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt
      721 gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg
      781 tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga
      841 tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt
      901 ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg
      961 cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat cctgttgcat
     1021 ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac
     1081 cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca
     1141 gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt
     1201 ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc
     1261 ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca
     1321 tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta
     1381 ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt
     1441 cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg
     1501 caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact
     1561 cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg
     1621 ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa
     1681 tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta
     1741 gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta
     1801 ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg
     1861 aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg
     1921 ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa
     1981 tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa
     2041 aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa gttcctccat
     2101 ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag atttctttgc
     2161 gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct gctttctttg
     2221 taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt attagtttac
     2281 catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc cgatactctt
     2341 tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa ttcaatactc
     2401 aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg gcttctagca
     2461 ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct aggactttta
     2521 ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa
     2581 caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa aagcggtatg
     2641 acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat
     2701 caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct ccgccatgat
     2761 ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa ccgactgcat
     2821 gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac aaataagtat
     2881 aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact agaagaaagc
     2941 gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa attcgttgct
     3001 gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt aaagcgtgat
     3061 aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa gactcggaac
     3121 attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat tcatgtaaga
     3181 atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac tgaaacaaaa
     3241 gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt ttcaactcca
     3301 acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga gcaacagaca
     3361 gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa acagctagca
     3421 gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc tgcccaagca
     3481 aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga tattggtcct
     3541 gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc tgacgaactg
     3601 cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca atcgatctat
     3661 gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc agtgaaatta
     3721 gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct ttaccagaaa
     3781 aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt gaaaatggaa
     3841 gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac tggcgatcag
     3901 atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga taaacgtacg
     3961 catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat ccgtttgatc
     4021 caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac agccattccg
     4081 ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga tgcagtaact
     4141 gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc agaaatgctg
     4201 aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc
     4261 cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg tatccaaaaa
     4321 gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga agaagatctg
     4381 aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact aaaacaaacg
     4441 cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct tctaacttct
     4501 ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca aaataaatga
     4561 tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc agacgaagca
     4621 tcaatacaat acaagtcaaa atggagacga ttggcaatag cggaacgaat ggcactttga
     4681 attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct agactaacaa
     4741 gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc aatgggaaaa
     4801 atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc ggtgtacgat
     4861 gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg acagcaaaca
     4921 gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc
     4981 ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca aaagccactg
     5041 ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc gtcacgatga
     5101 tgtaaaggac agtagcaatc agtatcgaac caatgattcc tcttggcaca tctttttgcg
     5161 ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca
     5221 caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc tgccagttat
     5281 caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca aatttgacat
     5341 ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg atgtaagtga
     5401 cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc ggattgtacc
     5461 cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct tgcatatagc
     5521 cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc
     5581 ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat ggcccaccaa
     5641 tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg acaacgattg
     5701 cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc gcaacccctg
     5761 tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc aaatcagacg
     5821 tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc ttacgaaaca
     5881 aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact gttttcatat
     5941 accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca taaatgagct
     6001 cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag ataatgatcc
     6061 ccatttgtga aagtgagaag ccaacagcta aaccaagtga tttgactgtt agaagcatgc
     6121 agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca aactgatcga
     6181 ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata ctttgaggta
     6241 agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat acaccataac
     6301 caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt ttattatctg
     6361 tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt acaagaagag
     6421 ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg aagaaaacgg
     6481 ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc cctacagaaa
     6541 cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa gctaagccgg
     6601 ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg aaaaagacaa
     6661 ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac
     6721 caattttacc acttactaaa ccaatactac cccatgccaa catagggact aatgctatta
     6781 aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca gcgaaaacgt
     6841 taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc attataaaaa
     6901 tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga ttcagccgtc
     6961 aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa tcctgttgaa
     7021 tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat ccgtttcaag
     7081 tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc
     7141 ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc attactaagc
     7201 aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg atcctcacca
     7261 acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg tatcacaggc
     7321 tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa actgtcgagt
     7381 cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc attttctagt
     7441 aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa tttagaagcg
     7501 gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg gtcttgttga
     7561 ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt gatatattct
     7621 tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa aggggaagtt
     7681 ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc acccagcaga
     7741 taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct caaatcaact
     7801 ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa cagccatccc
     7861 aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct
     7921 ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg atacctgcct
     7981 gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca tctacaaatc
     8041 gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt ccattgtgct
     8101 tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc tctccgttga
     8161 tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc atttcactag
     8221 ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca atcagtacat
     8281 cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc atgatcatat
     8341 ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact tcacgtattt
     8401 tttgacacca ataatagcca tccaaaacgg gaagattaat atctagtaat acaagctgtg
     8461 gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca aaggtttcaa
     8521 attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg tcttcgacta
     8581 ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca atatcaaaga
     8641 agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa
     8701 actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt
     8761 attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt cttttaaatt
     8821 ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga aggagtataa
     8881 gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact tcttctgtaa
     8941 agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag
     9001 tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt tttgttggaa
     9061 ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact tcaagataga
     9121 atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca gcaataccgc
     9181 tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag gtgccttgca
     9241 ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa ggcaagctaa
     9301 cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat tcttttcctg
     9361 gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc attcctggga
     9421 ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat tgttgctcat
     9481 gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt ctttgatcca
     9541 aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa
     9601 acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt ctattaccta
     9661 ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc tttataaaac
     9721 cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga tttacggtac
     9781 cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa gagcccgttc
     9841 ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg ccctggattt
     9901 tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat aaattcagta
     9961 aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc tttcatttga
    10021 taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc gacaaattct
    10081 gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata aacagctaaa
    10141 ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca caattcgaat
    10201 cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt tcttccacct
    10261 gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc atttcgtccg
    10321 atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt ggaaaccttc
    10381 aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc taaagtatct
    10441 actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt gcttactact
    10501 tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc
    10561 tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt tttgataaca
    10621 gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa
    10681 gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc tccagcttca
    10741 ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt atctgcttct
    10801 ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa
    10861 ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac aaccattgga
    10921 gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata gactttatct
    10981 ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc tccagcttca
    11041 ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact ttctgtgtgc
    11101 cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg ttccggtgtt
    11161 aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg
    11221 actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt cggtcgttct
    11281 tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact tggtttttgt
    11341 gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc cgcagtaacg
    11401 agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt ctccccgttc
    11461 tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag aaatcaacgt
    11521 tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg gattgcttgg
    11581 accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat aaacacgtgg
    11641 tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag ccatctcctg
    11701 tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt cagggatgat
    11761 gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt ttaattcttc
    11821 aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc cctctttatc
    11881 cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg gtttgatcca
    11941 ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc cttctatcat
    12001 ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg ttcctctttg
    12061 acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag gatagatatg
    12121 aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa tagcagcaat
    12181 tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa tcgattcttc
    12241 gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga tacgtgcaat
    12301 cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc ctatttggac
    12361 aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag cgatttgctg
    12421 gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat aatcggtcat
    12481 gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga tatctgctgt
    12541 ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa attgatcgtt
    12601 ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat cttcccctga
    12661 ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta aaacaagtaa
    12721 ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt agattgtctg
    12781 acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag caggatatag
    12841 aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt cccgacacta
    12901 agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg ctgtagatca
    12961 ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt acccgcttct
    13021 tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact aatttctaaa
    13081 ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt gatccgatag
    13141 accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc tggtgccaag
    13201 cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga aaattctgcg
    13261 ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc gattggcgct
    13321 agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc ttccggcaag
    13381 ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc ttcattcagt
    13441 gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga ttccgagacc
    13501 tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac atacttttct
    13561 actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga ttcttctggt
    13621 tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc cactttcctg
    13681 atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct aactcggatc
    13741 tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc ctcttcatct
    13801 gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg gatagtccct
    13861 atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc tttgaaacct
    13921 tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc ttcactatcc
    13981 ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc atccacgatt
    14041 acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc ttcctctact
    14101 tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc gttaccatct
    14161 gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc aattagttta
    14221 ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac atacaactca
    14281 tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg atattctcct
    14341 tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc agatgtatat
    14401 tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata ttttttgatt
    14461 tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat ctctctgatc
    14521 caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt cgtttcaaag
    14581 atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc cccactctct
    14641 ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt ttgacccttc
    14701 ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga tgggaaatac
    14761 atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata ggccatattg
    14821 ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg gtacttgatc
    14881 ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg gttttcccgt
    14941 ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg acgttcttca
    15001 tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag atggtaaaac
    15061 tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt ttcatcataa
    15121 agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa ggctgtaaca
    15181 atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc ttctaaatca
    15241 gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc gctaacgttt
    15301 ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata cttgtttttc
    15361 agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga agtaggactg
    15421 ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt attatctcct
    15481 tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg gttaaagtca
    15541 gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga aaactcctca
    15601 aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac agtccagttg
    15661 ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata actgaaggtc
    15721 ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc tccgccattg
    15781 tctttataca atgtttcata gccattttta agccctagtg taagcggagt tcctccgatt
    15841 ggtgtacgat ttaatgctgt attctcactt cccgtcaaac gattgatatc atttgtcaat
    15901 ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt atggtaaaaa
    15961 ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt actcatttcg
    16021 tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc ggttaattca
    16081 ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat ttcctttttc
    16141 tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc aggatgtaga
    16201 tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta cgccccgtta
    16261 taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac ggtttgagct
    16321 ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata gtcgtaattt
    16381 cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc tccgtcatat
    16441 ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc taacactttt
    16501 gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac ttctccgcta
    16561 ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc caaaataccg
    16621 ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat tggttcgtcc
    16681 agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc tgtatcagtt
    16741 tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg aagaggtagt
    16801 tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct
    16861 tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc gacttttagg
    16921 tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt tacggtacca
    16981 atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc actttccttt
    17041 ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt cccttcaatt
    17101 tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga ctcagcagct
    17161 acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag caaactgaca
    17221 gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc ctttcaaaaa
    17281 tatttgtctt ctttcacaac aatcaacaaa a
//
LOCUS       DACCVH010000057        16770 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.057, whole genome shotgun sequence.
ACCESSION   DACCVH010000057 DACCVH010000000
VERSION     DACCVH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.057"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..304)
                     /locus_tag="IVV98_001970"
     CDS             complement(<1..304)
                     /locus_tag="IVV98_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7807607.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKS"
     gene            complement(306..503)
                     /locus_tag="IVV98_001971"
     CDS             complement(306..503)
                     /locus_tag="IVV98_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP7807608.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(897..2624)
                     /locus_tag="IVV98_001972"
     CDS             complement(897..2624)
                     /locus_tag="IVV98_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7807609.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2617..3810)
                     /locus_tag="IVV98_001973"
     CDS             complement(2617..3810)
                     /locus_tag="IVV98_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7807610.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3997..4641)
                     /locus_tag="IVV98_001974"
     CDS             complement(3997..4641)
                     /locus_tag="IVV98_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807611.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4735..4869)
                     /locus_tag="IVV98_001975"
     CDS             complement(4735..4869)
                     /locus_tag="IVV98_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP7807612.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4871..7003)
                     /gene="feoB"
                     /locus_tag="IVV98_001976"
     CDS             complement(4871..7003)
                     /gene="feoB"
                     /locus_tag="IVV98_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP7807613.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7000..7473)
                     /locus_tag="IVV98_001977"
     CDS             complement(7000..7473)
                     /locus_tag="IVV98_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP7807614.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7874..8098
                     /gene="nrdH"
                     /locus_tag="IVV98_001978"
     CDS             7874..8098
                     /gene="nrdH"
                     /locus_tag="IVV98_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP7807615.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8257..10416
                     /gene="nrdE"
                     /locus_tag="IVV98_001979"
     CDS             8257..10416
                     /gene="nrdE"
                     /locus_tag="IVV98_001979"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP7807616.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10466..11431
                     /gene="nrdF"
                     /locus_tag="IVV98_001980"
     CDS             10466..11431
                     /gene="nrdF"
                     /locus_tag="IVV98_001980"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP7807617.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11520..12659)
                     /locus_tag="IVV98_001981"
     CDS             complement(11520..12659)
                     /locus_tag="IVV98_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7807618.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12968..13681)
                     /locus_tag="IVV98_001982"
     CDS             complement(12968..13681)
                     /locus_tag="IVV98_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP7807619.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13935..14636)
                     /gene="nagB"
                     /locus_tag="IVV98_001983"
     CDS             complement(13935..14636)
                     /gene="nagB"
                     /locus_tag="IVV98_001983"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP7807620.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14870..16402
                     /locus_tag="IVV98_001984"
     CDS             14870..16402
                     /locus_tag="IVV98_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7807621.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16593..>16770)
                     /locus_tag="IVV98_001985"
     CDS             complement(16593..>16770)
                     /locus_tag="IVV98_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807622.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5206 a         3452 c         2888 g         5224 t
ORIGIN      
        1 gagatttatc tccataatct gctcgatata aaccatttat tccagcagtt cttccaattt
       61 cactcaaatt tcttattaat tcctcttgat attcagtgaa tcttatttta ttagtataag
      121 cagtaaaata tagataattc accaatctat ttattaaagg actgggatct aattcatatt
      181 tttgtttttc taattttaaa tatacctttt gtaaaacctc aagaatatca gaatatttag
      241 gatctttact tatagatata tcattatata attcatgaac aatttgctta gcattttttt
      301 tcattttagc acttccctgg aattgctcca cctaaaaaac cacctataga cattcctgca
      361 atacaagtag ttgccttggc ccaatcgacc gtacatttat ttttagtgca atacactcca
      421 tttccataat attttccact atgagtggta cccccataga taagttgtgt ctctttaata
      481 gacaaaattt ttaaatgttt cataatctaa tcacccctaa attaatgttt ttagactatt
      541 attctaacat tcattaaatt tcaaaaaaca attccttctt gaaacgtagc aaaataattc
      601 ctgaataaga atttaatcac ttttaagtat ataaactatg tatattcttt aatatttttt
      661 gagaatgcac ttcgtacata ataaacttta atcacattag tctttcatac ctacgatcga
      721 tctctttgac tcgcacccat aaattcataa tagtttgtcg gcgtctttga acgtttcgaa
      781 gatgagctac gcattctctt tttttataga caaaaaagat agagacgaac atggagcttc
      841 caaatttgga tatttgatcc aattttggaa gctccattta tttcgtgtct gtctttttat
      901 tttttccagc tttcgactaa ttcttggttc tctttgatcc agtcttttgc tgcttgctgt
      961 ggatcttttc cattgttgat ttccaacata actttttcca tatctttttc tgaccaatgg
     1021 aaattgtcta atactttgta agcttctggc tggtcttctt tcaatccttt tcgaaccatc
     1081 gtatggatct gctcttcgct tcccattccg ttttcaggat cttctaagta tttcagatca
     1141 tatttggcaa acatccaatg aggtgtccat cctgtaacta caattggttc gtgttttttg
     1201 atcgcttgac ctagtgcaac ggtcattgct cctgaagaag atgtctctac tttccagtct
     1261 ttcaagttgt catatttttg gatcgtgttt tcagcagccg taactacacc agctcctggc
     1321 tcgattccta tgattttctt acctgcctga tcggttaact catcgatcga atttacatcc
     1381 atgtaggctg gcactgctaa accaactttt gctcctgtca aattggcacc taggtcttcg
     1441 acttgatctt tatattgtgc atattgtgaa ccatgagttt taggtagcca agctgaaacc
     1501 atggcatctg actcgccatt tgaaacagat ttccacatga ttgaattatc taatggcgtc
     1561 atcgttacat catagcccat ttgtttcaat acttcaccga ctacatttgt tgaagcaact
     1621 tctgtatccc attcaacata agataagttg atacgttttg tttctttggc agatgaaaaa
     1681 ctccctatac caatcgcacc taagatcact actactacag caccaatgat cagtccttga
     1741 cgttttttac ttttctgtgt tgttgctcct gcagcttttt tattgtttgg ctggttcaaa
     1801 tgctgtgtaa aacggtcaat gatgattgct aagataacta atgcaacccc gttgacaaat
     1861 ccattcccga cttgtgctct ttgcaatgct gataatacgc cgcgtcctaa gccgggtgca
     1921 ccgatcatag aggcaataac gaccattgaa agtgacagca ttgttgtttg attgatccct
     1981 gccatgatcg tacttttagc taaaggcaat tctagtttga atagtttttg acgacttgtg
     2041 ctcccgaatg aatcagaagc ttctactaat tctttaggaa cttgtcgaat ccctaaattc
     2101 gtaaaacgaa cggttggtgg cagagcaaag atgactgagg caaatacccc tggaaccatc
     2161 ccgataccga aaaatgcaac tgctggaatc aaataaacga atcctggcat tgtctgcata
     2221 aagtcaagga tcggtttgat aatactttgg gctttactgc tttttgccat caagatccct
     2281 aatggtaccc caatgatgat cgagatcaca ctagataaaa gaacaagtgt gacagtattc
     2341 atcaaatcat tccatagacc ttggttataa ataaaccata gaccgattaa tgtgaacaac
     2401 gtaagtcctg gacgtttctt agaaataaag aaagctgcta ccgtcaataa caagataaac
     2461 aaaggagctg gaatcactaa cagtaaattt gtaatccccg acatcactgc ctgtccaatc
     2521 gtttgtaaaa atgaaaatag gccagaaaaa gttgtcgtaa accattctgt gatattttct
     2581 acccagtttg ccactggtaa ttgatagttc aatagattat tcatgttcac tcacctcgct
     2641 tgtttctgct aatgcttcaa tcacactacc tcggatgacg acacctttta attttccatc
     2701 ctctacaact gcaagtggag tcggtgagtc ataaataata ttgaaaatat cacttaccac
     2761 catgtctttc ccaatcaccg tcacattttc atctaggaag tcgatcaatg gacgtttttg
     2821 cttcctagct tctaacgctt gatctgcagt gatgatccct ttcaggtgtc tctttctgtc
     2881 aacagccatc agcatgctga cttcttcatt acgcatcctt gtcaatgcaa cgtttggtcc
     2941 atcagattcg atattcgtcg tcaatgcagg taccatgatg ttttgagccg taagcacttt
     3001 ggaacgatcg acttcttcca caaattcacg tacataatca tttgctggat tggtcaatat
     3061 ttcttcacct gttccgatct gcatgatttc gccgtctttc atcaaggcga ttctgtcccc
     3121 aatccgtaaa gcttcattca aatcatgggt aatgaaaata atcgtttttt gaacattggc
     3181 ttgcaggtcc agtaattcgt cttgcatttc tcgccggatc agcggatcaa gagccgagaa
     3241 cgcttcgtcc atcagcaaga tctcaggatc atttgctaaa gctctggcta ggccaacccg
     3301 ttgttgcatc ccaccagata actgactagg atattggtct ttaaatgaaa gcaaactaga
     3361 attttctaat gctttttctg ctttttcttg tcgttcttct ttaggtacac cacggacttc
     3421 taacccgtat tctgtatttt ccaagatcgt tcgatgtgga aacagaccga agttttggaa
     3481 aaccatattg attttatgac gacggacttc tcgcaattct tctttgctta acttcgatac
     3541 atcttctcca tcaatataga tactgcccga agttggctca atcagacgat tcaatagacg
     3601 gatcaatgtg gatttcccac tcccggaaag ccccatgatc acgaagattt ctccttcttt
     3661 tacgtcaaaa ttcacgtcat acacaccaac cgttgcaccg gttttcttta aaatctccgt
     3721 tttcggctgg tgatcattca tcatatctaa agcggcttgt gtctttttac caaatatctt
     3781 tgttaaatgt tttacttcta cttttaccaa acaaattctc cttttttatg taaattcatt
     3841 tttctttctg aaaaaagtga ccacactatg ttaacatcat gtagtcactt tgtcaaaaat
     3901 gaaagaaatt tgcttgtcca aactgaaaaa aacttggcta aatctttgta aataaaaggt
     3961 ttagccaagt taatattttt ttaatatttc acacaatcat tctgcaagct gatgctccgg
     4021 gtaaaaaaag tttgtcatac gctgtagtgt atattcattt ccaataaaat gaacgatgtc
     4081 ccctgccgta aatttagcat aggggccagg tgaaacaagc agttcttcat tatgagaaat
     4141 tgcgataact gtggcgccag tcgcctgcca gatattcaac tcgctaattg aacggtccag
     4201 atgcattgct ttttctgata aagataattc aaacggaagt aaaggattca tcttatgtat
     4261 tcgcttcgtt tgattgacca gctgatccaa taattgagaa aaatgattca gctcatcttg
     4321 ttgcttctcc acacttgcca tgatttctgc ttttgtatct tggatggatt gtacatcttg
     4381 atattgcaat aggaaatctt ttgctttttc cttcgaagca acaaatgccc cacttccatg
     4441 ccgtacttcc atgattccaa gatctaccag cacattgata gccttgcggg tagtctcagg
     4501 agaagcattg tacgtactgg caagtgttga gcgggcatgg atcttctcac ccactttata
     4561 tcggttttca acgatacgtt cggctaaatc aacagcaatc tgctggtagc gcgggcggac
     4621 gatttttttc tttccagaca ttttctttcc tctttctttt tttactttcc ctcatcttac
     4681 tatgctctag caaaataagc aaaaaagggg agaatagcct cttgcaacga ctgatcatcg
     4741 cttgatctgt tcctttttta ctgggcaagc tgtttgacag tcatcacaat tcttaccgga
     4801 ttttaaacga gtatagacaa ttgcgcctgc acttccaaag attaacacac ttaataagaa
     4861 tgtcgccatc ctattcctct ccttctaatg acaatatagt ataaaactgg ttcttggatt
     4921 ttggctgacg gaacaaaaca taaacgagtc ctatcatcag taaaatagca agatacgtcc
     4981 ctaacgctac ctgtccaccc tccaataagt gtcccaactg ataaatcaca aaactaacta
     5041 aataagctaa accgcattga tagcctatgg cgatccaagt ccatttcttg gcattcattt
     5101 cccgatggat agccccaatt gccgcaaaac aaggcgcaca aagtaaattg aaggctaaca
     5161 atgaataagc tgctgcggga gtatatgtgt gttgtagcac ttgccagatt tctctgccat
     5221 tttcggatac ttccgcatga ccaaacaaaa taccaaatgt gccaataata ttttctttag
     5281 cgaccaatcc tgtaatcgct gcgactgttc cttgccagtt tccccaacca agcggctgaa
     5341 aaacaactgc caggattcgc ccgaaaaagg ctaagatact ttggtcttca gaaacaggtt
     5401 gagcataaaa attataagaa gagctgaacc agatcacgat actagaaaca aagataatcg
     5461 ttcctgcttt tttaacaaaa gacttgctgc ggtcataggt ttgtcttagg accgctgacc
     5521 attgaggaaa atgatatgcg ggcaattcca tgataaaagg agctgtatct ccagcaaaca
     5581 aacgtgtttt tttcaagctg attccagaga aaataattgc agtcatacca agaaaatagg
     5641 cagaaggagc tacccaagat tgatgaggaa aaaaggcccc tgctactaag gcaataatcg
     5701 gcaactttgc agaacaaggc atgaaggttg tgaccatgat cgtcaaacga cgatcttgct
     5761 cgttttcaat cgtgcgactg gccatgacgc ctggcactcc acatcctgta gcaatcagca
     5821 taggaatgaa ggattttcct gaaagaccga atttcctgaa aagtcgatcc atgacaaaag
     5881 cgatcctcgc catatatccg cagtcttcca gaaagctcaa gcataaaaac aatataatca
     5941 attgcggtag aaatcctaac actgctccca cgcctgcgat gatgccgttc aagatcagct
     6001 cctgcatcca tcccgctact tgccattcag ctaacaatct gccaacatgt tctggtaacc
     6061 atgtaccaaa caatgtgtca ttgatccaat ctgtccccat tgttcctact gtttgaatag
     6121 ccagataata gatcagccac atcacaaatg cgaagatcgg caaggctaac caacgattcg
     6181 ttgcaatctg atcgattttg tcactcatcg ataattggaa agaatcattt gacacaacac
     6241 agagtgtaca tagttgggta ataaattcat aacgttcatt gaccagaatc gtctcactat
     6301 cgtcgtccaa tagtttctct gttaactgga tcagttgctc gatctctttt tgctgagaaa
     6361 ctgctatctc gtaatcctct cttaccttct gatctcgttc aaaatatttc attgcatacc
     6421 agcgtttctt gccgctttgt tctcctagta catcttcaat ttcatgtaaa gctgcttcta
     6481 aacgtggatc atatgtacag ggaacaggaa tagaaggccg cttttttgca gactcctgaa
     6541 tcttttcgat tagtttttcg attccttgct ttttcaatac gctgattggt aaaactggta
     6601 caccaagacc ataggaaagc ttttctagat tgattttttt tccttctttt ttgatgacat
     6661 ccatcatatt cagaccaatg atcataggaa tgtctaaatc caataactgc gtagttaaat
     6721 aaagatttcg ttctaaattg gtagcatcaa taatgttgat gatcagttca ggctgttcct
     6781 gaaccaaata atctcttgca atcacttctt ctggtgtata aggagacaaa gaatagatgc
     6841 cgggtaggtc ctgaatatga atgttcggat tttttttcaa cgatccttct tttttttcta
     6901 ctgttacgcc cggccaattc cctacatatt gattcgaacc agtcaagaga ttgaacaagc
     6961 tagttttccc gctgtttgga tttccgacta acgcgatatt cattcttttt cctccctttg
     7021 tatcaagatt agttcggcct ctgactttcg taacgtcagt tcataccctc gcactgtcag
     7081 ttcgattgga tctcccagag gggctagttt tcggataact atttttacat ttcgcgtcaa
     7141 tcccatatcc attaaccgtc gcttcactgc gccttgtccg tggattgcta cgacgatccc
     7201 agtctctcct gcttttaatt gatcaagaga agtccagctt tcagaggaag cagtcttttt
     7261 attgacaaag atttgaccta gtatttcccg acttactgcc actcgatgac tttttaccag
     7321 taaaatggca ttgttgcctg ataaattgac gacgacgatt ttacttccgg caacgatccc
     7381 gatattttgc aaatggcgtt ttgttttttc ttctgtttcg attcgttcga cttgataaac
     7441 gaaattctgc tttgcctgcg ctaaggtctg catattgatt cctctcttgt gaaataaatc
     7501 atgtattaaa atcattcatt atatgttcta attttcttac gtgttacgca aataaatgag
     7561 aatcattctc acatagaata ctctcggtaa ttgagaatgt caattatact tgtgatatta
     7621 tgagcgaatc tttagtattg atagataaaa atgagaaaaa aatatttctt catagttttc
     7681 cacaattttt tctctattaa atttgctatt ttcccacacg atacttgttt tcagctcttt
     7741 tttcaaaaac acaaaactta gtattccaca gtttccacaa cacaatatgt agtgtttgtt
     7801 gtttgacttt tttactaaga gttttatact atctattata gataataaga atgtgttaga
     7861 ggaggcactc accatgaacg taaaaatctt ttctaaaaat aattgtatgc aatgtaagat
     7921 ggtcaaacgg tttttaacag aaaatcaaat tgcttttgaa gaagtcaata tcgatgaaca
     7981 gcctgaagca gtagactggt tgaaagcaca aggattccaa agtgttcctg tcattacttc
     8041 tgatgcagaa acagttatcg gattccgtcc tgatcagttg cgtaaacttg ccagctaaca
     8101 tgactaaaag aatcaaaacg tgatacatgg atttgaaggg cttgagacag caccagtttt
     8161 tgtcgcaaac ttccaaatcc ttttttaaag cttaaaaaca atgcaatgat ttgcaatcaa
     8221 gcatcatcaa atacgaaatg aaggttgggc gtacgtatga gtcttaaaaa tttacaagat
     8281 gtcagttatt tcaagctgaa taatgaaatc aatcggccag tcaatggtca aatccctttg
     8341 aataaggata aagaagcttt agttgccttt tttgaggaaa atgtcaaacc aaatacgatg
     8401 acttttccat ctattatgga aaaaatcaat tacttgatcg atcaagaata tatagaagca
     8461 gaattcattc aattgtattc accatcattt attgaaaagc tatatcaatt tttggacgag
     8521 caacattttt ctttcaaatc ttttatggct gcttacaaat tttattctca atatgcgttg
     8581 aaaaccaacg acggttccgc ttatctggaa acttatgaag atcgagtagc cttcaatgcg
     8641 ctttactttg cgaacgggga tgaagaatta gcacttgctc ttgcagacga aatgatccat
     8701 caacgatatc agccagctac accttctttc ttgaatgctg gacgtaaacg tcggggcgaa
     8761 ttggtgtctt gtttcttgac tcaagtcact gacgatatga actctatcgg gcgctcaatc
     8821 aactctgctt tgcaattgtc ccgtattggt ggcggcgtag ggattacttt atcaaatctt
     8881 cgtgaagccg gcgctcctat caaaggatat gagggtgctg caagtggtgt cgttccagtc
     8941 atgaaattat tcgaagatag tttcagctat tctaatcaat taggtcagcg tcaaggagct
     9001 ggcgtggttt atttgaacgt tttccatcca gacattattg ctttcctttc agcaaaaaaa
     9061 gaaaatgcag atgaaaagat tcgcgtaaaa actctttctc ttggcgtgat cgtacctgat
     9121 aaattttatg aattgacacg taaaaacgaa gatatgtatt tatttagtcc atatagtgtc
     9181 gaaaaagaat atggtgtccc attctcttat gtaaatatta cagctgagta tgatcatcta
     9241 gttgcaaatc caaacattcg caaacaaaaa atcaaagcgc gtgatcttga aaatgaaatc
     9301 tcaaaattac aacaagaatc tggctatcct tacgtaatca atattgatac agcgaaccgc
     9361 gagaatccaa tcgatggcaa gatcatcatg agtaatttat gttcagagat tttacaagtt
     9421 caaacgcctt ctgtgattaa cggcaaacag gaatatgaag tattaggaac agatatctca
     9481 tgtaacttag gctcgacaaa tatcgtgaat ttgatgcaaa gccctaactt tggtcaatct
     9541 gtgcgtacga tgactcgtgc attgacattt attacagatg catctgatat cgatgtcgta
     9601 ccaccgatcc aaaacggaaa taagctgaat catacgattg gattaggtgc catgggctta
     9661 cacacttatc ttgcaaaaga acaaatggaa tatggctcag aggattcatt agactttaca
     9721 aatatttact tcatgctgtt gaattattgg acacttgttg aaagcaacaa tatcgctcgt
     9781 gaaagaaaac aagttttcca taattttgaa aaatcagctt atgctgacgg cacttatttc
     9841 gaaaaatacg taactggaga attccagcca aaatcagaaa aagtcaaagc attgtttgaa
     9901 ggcattttta tcccaactgc tgaagattgg aatgctttga aacaagcagt aatgaaagat
     9961 ggactgtatc atcaaaatcg cttggcagta gcaccaaatg gctcaatttc atatatcaac
    10021 gatacgagtg caagtattca tcctatcact cgcatgatcg aagaacgcca agagaagaaa
    10081 atcggtaaaa tttattaccc agcgccttat ctatccaatg agacgattcc gtattacact
    10141 tctgcttatg atatggacat gcgtaaagta atcgatgttt atgcaacggc acaacaacac
    10201 gtcgatcaag gcatgagttt gactttattc atgcgttctg aaatcccaga aggcatttat
    10261 gaatggaaga caacaacgaa gcaaacgaca cgtgatttga atattttaag acattacgct
    10321 ttccacaaag gaatcaaatc catttattac gtacgtacct ttactgatga tgcagaagaa
    10381 atcggaagca atcaatgtga aagctgcgtg atctaatatc atagatagat tcgcttattc
    10441 atattttaat taaaggagca ttctcatgtc agaaacatat tatgaagcaa taaactggaa
    10501 tgaaattgaa gatatcattg ataaatccac ttgggagaag ctgacagagc aattttggct
    10561 agatacacgt atcccacttt caaatgacct agatgattgg cgtacattgt ctcaattgga
    10621 aaaagataca gtaggacatg tatttggcgg tttgacactg ctagatactg tccaatctga
    10681 aagtggcatg gatcagttgc gtaaagatgt ccgcactccc catgaagaag ccgttttgaa
    10741 caatattcaa ttcatggaat ccgttcatgc caaaagttat tcttctattt ttagtacact
    10801 gaatacgaaa aaagaaatcg aagaaatttt tgactggaca aatacgaatc cttatctgca
    10861 aaaaaaagct gagcgtatca atgaaatcta caaacacggt acaccgctag aaaagaaaat
    10921 tgccagcgtc tttttagaaa cattcttgtt ctattcaggt ttttatactc ctctttatta
    10981 tttaggaaac aacaaattgg ctaacgtagc agagatcatc aaactaatca tccgagatga
    11041 atctgtacat ggaacctaca tcggttacaa attccaatta ggattcaacg agttacctga
    11101 agcagaacaa gaaacgttaa aagactggat gtacaatctt ctttatgagc tttacgaaaa
    11161 cgaagaacgt tatacagaag aattatacga tccaatcggc tggacagaag aagtcaagac
    11221 attcctacgc tataatgcca acaaagcatt gatgaaccta gggatggatc cactctttcc
    11281 agatactgcc aatgatgtca acccaatcgt aatgaacggg atttcaacag gcacaagcaa
    11341 ccatgacttc ttctcacaag tcggaaacgg ctatttgtta ggtcatgtag aagcgatgaa
    11401 agacgacgat tatttgattg gattggaata aggatttatt ttaattcaaa aatttttcga
    11461 aaaataaaaa gagtttagcg tacagatatt ttaaatgtac actgaactct tttttatgct
    11521 tattcacttg tttcttccag cacttttgga ctgtctaact tttccgaaac atgttccatt
    11581 cttctcaata aatagatttt ccggatattt aatattatcg tcttaatcac tgcatagaca
    11641 ggtatgcaaa tcagcatgcc taatattcct gcgacacttc ctgctccaat caataccaag
    11701 atgatcgtca aaggatggat attcattgat ttcccaaata acaacggctt gatcaaattt
    11761 ccatctaatt gttggatcac taaaatcgac aacgccatat acaaagcttg aaatggagag
    11821 ataaacaaac cgacaatgat tgctggtacc gctccaataa aagggccgac atacgggata
    11881 atattcgtga ttccgcaaat gaccgcaagc aacaagctat aaggctgatc gaatattctc
    11941 attgccaaaa agctcattac accaataatc aaagcatcta agatcgtact gctgatatag
    12001 gcagataatg tttcgtttaa ttcttttacc gtttggcgta actctttacg aatcgctttc
    12061 ggaaagaagt gagacaacgc atcaataaat ttgtgcccat ccttgaacat aaatagcaaa
    12121 ataaatggaa cggtaaataa caaaataaaa aattgcatca taaatgaaat gatttttgag
    12181 acacttgcag ataaactgac taatatgata ttgaacaaat tactaagaga taaatttgct
    12241 gatgctaatt gttcttccaa attgaaattt ttaaactctt cccgctgcgc caattcattt
    12301 aaccatttgc ttgtttcatc tgcatacatt ggcaagctct gggtcaattg aattgtctgt
    12361 tccattaact gaggcactac attcatgaca gttaaaacaa ctaaaatgat tacgaccaaa
    12421 aacgtcaata aaaaaccgaa cactctcggg atccgatgct tttcgagaaa aacaacgatt
    12481 ggatcgaaca tataatagat aaaaccagca acaagcaatg gtaaaaaaat tgccgaaagc
    12541 attttcaata ttggactaaa aatattcggc atttgtaaaa taaagtacac gccgatgatc
    12601 gtgagtacta gctccactgt ccagaaaaat aattttgatt gtttaaaacg tgattgcata
    12661 catctcctcc aaggtccttt gatacttcta ttctatcatt taacaaagag ttacgcgctg
    12721 agattttcat ttgcttaaaa aaaacaaaaa aaataaacat attttaatga gtagacgagt
    12781 acttaaacaa aaacacggtt tggagtagtg acaaaaatta tactgcagtc cctttttcca
    12841 aataaacggt gttcaaaagc ttgcatcttc gtaataagcc cagccaaacg aaaaatataa
    12901 ggaactattt ttatttggct gggcttatta cttgatgtag gacatctatt ttacaacctc
    12961 agatcattta ttgcgcaata ctgactaaat gcaactttgt gatatttttg tgtacggaca
    13021 actcctcgat cacatcggca taagtgagcc cttttggaag atcaatcgta tagatatttt
    13081 tgtacactcg gtagtcatca acgaatttta cgtcaaaatt cacatcttcg attacgatat
    13141 ttttctcttc aaaataatcg gtaagaaaat ctttggtttc ttttctatgg ataaattgga
    13201 tttctaactt tttagtcgta ggtacatgga tcacgcgttt cactactgtg agtgcaatag
    13261 caatcccgat aaaactgatg atcgcaatgg aatagtaacc catgccgatg gcgatcccta
    13321 atccagcaat tgcccataaa gaagcggcag tcgtaagtcc cgtcaccgat tgtttcgtga
    13381 cgatgatcgt tcccgcgcct aagaaaccga caccactcac cacttgagca atcagccttg
    13441 cttcatctga acgaatcgtt ccagcaagct gtggatactc taaagcatct cttaatgcac
    13501 cactagcgat ctcaacttgg atcaatgcaa tgatacatgc tcccatacaa actaaaatat
    13561 gcgtacgcat acctgctgga cgatttttat attgtcgttc aaaaccgatt gctccgccaa
    13621 atagcatagc gatccctaaa cgtaaaataa tctctggaat tgtcaatacc atatcattca
    13681 tctaaacacc ctccagtcca atatatcatg tctgaaagga gcagacaaaa aaagtgcaat
    13741 ttttacctct tacgaaaaaa ggactgtgac aaaatttttg tcatagtcct ttttatgaat
    13801 aaacggtgtt caatcagctg accctcggta ttactcaaca aacggcaaaa tatggggagc
    13861 tatttttcct ttgtcttctc taatactcag gtcaaaacgc tgatttcaca acctctttag
    13921 cctactattg aaaattacaa cttacttgct gcttcttcat cgatgatcac aacaacattg
    13981 tcgtgatttt gcaatacact tgctggcaaa tgattcgtta caggtccttc aatcatccct
    14041 ttgattgcat cagctttgct ttcgccaaat gccatcaaga cgatttcttt acttttcata
    14101 attgaaccga ttcccattga aacagctttt gttggtacat cttctgcttt atcgaagaat
    14161 cgtttgtttg cattgattgt tgattctgtt aagtcaacta ctgaagtcgt tccgtcaaat
    14221 gaagcaccag gttcattgaa accgatatgt ccattttgcc cgattcctaa gatttggata
    14281 tcgattggat gtgcatcgat gatttgatca tactttttgc atgctgcttc cagatcttct
    14341 gcttttccat ctggtacaaa cgtttctttg aatggttttt tatcaaataa ttggacatcc
    14401 atgaaatgac ggtagctttg ttcatctgaa ccgcctagtc caacgtactc atctaagttt
    14461 acagaagtca tttcactgaa atccaaatcg cttgaagtca tttctttata taaagtaact
    14521 ggtgtgcttc ctgttgccaa tcctaatact tttgcacctt tgttcatacc ttctttgatg
    14581 atttcaaatg ctttttttcc gccttcttca gcgtttttta cacgaatgat ttccatagtg
    14641 attgctcctt tatattttgg tatagcccaa ttatagcatt ctttttttct ttttacaata
    14701 attagtatag accaaattgc atttttttca ttttcttgac aataaatagg aatccgtgtt
    14761 aggtttcata agatggttca atcaaacaat ccatgttgca tgaaaaccaa gcaagtgatt
    14821 cactgtggac gctttatgtc tgcagttttt ttatgaaaaa ggagttatta tgagtatact
    14881 gacattaaac aacattaccc agcaatttgg cgacaaaatc ctctatgaag gtgtcgatct
    14941 gcaattaaat gctggcgaac atcttgggct gattggacaa aacggagccg gtaaaagtac
    15001 attgattaaa atcatcactg gtgagatctt accagatgac ggacagatcc attggcaaaa
    15061 aaatattcac aaaggttacc tcgatcaata tgtggaagtc gatgaaacat taacaatcga
    15121 agaatttcta aaaactgcgt acgcaaaaga atacgaaaag gaagaaaaaa ttgcttttct
    15181 ttaccaaaca tatagcgaga ccttcgatga ttccttgctg gaaaaagctg ggaaactcca
    15241 aacggaatta gaccaaggag tgttttatca aatcgacacc ttagttgctg agatgagcag
    15301 cgggttgggg atcgatgtct taggtttaga ttcactgttg aaaaatctaa gtggtggaca
    15361 acgttcaaag gtgattttag caaaactact tttagaaaac ccagatgttc tgatcttaga
    15421 tgaaccaacc aatcacttag atgatcagca tatccaatgg ctgacgcagt ttcttcagga
    15481 ttttgacggt gcgtatatcg tgatttccca tgaccaagaa tttcttgatc agatcaccac
    15541 ccatatcgca gacatcgagt ttggaaagat tactaagtat actggccatc taaaacaagc
    15601 attgaaacaa aaggaacaaa atcgcgaaag ctatttgcgc caatatcatg ctcaacaaaa
    15661 acaaatcgaa aagaccgaag cttatattcg aaaatacaaa gccggttccc gatcaacgat
    15721 ggcaaaaagc cgacaaaaac aattagataa aatcgaacgg ctgacgcctc cagcttcagc
    15781 aagtaaagct gtctttgatt ttccattctc gcctattgtc acgacattag cagtggaaac
    15841 aactgattta gtcatcggat atgatcgacc gctacttgca cccatcaatt tgaccatccg
    15901 ctttggtgaa aatattgcca ttcgaggctt caacgggatt ggaaaatcta ctttattaaa
    15961 aacactgatc ggtgagattg aaaaaataag tggcgatttc cacttcccag ataacacaaa
    16021 aatcaattac ttttcacaag atctgtactg ggaaaatcca ttagaaacac cactacaata
    16081 tttaagcagt caatttccaa aagcgactat caaagaatta cgtcgccaac tagctaaagc
    16141 agggttagtt aatcaattag caagtgaacc tctcactaca ttaagtggtg gggaacaaac
    16201 taaggtgaaa cttgcacagt tgacaatgaa ccaaggtaat ttactgattc tcgatgaacc
    16261 gacgaaccat atcgatcaag aaacgaaaga aagcttacaa gacgggatac agaaatttcc
    16321 aggaacagta atcatcgtct ctcatgaaca agaattttat caagatcttg tgcaacgagt
    16381 cattgagatt gaaccaaaat aaacgtttga ttgaatagtt gaaaaaaagg agctgtgaca
    16441 aaagttttgt cacaactcct tcttctgaat aaatggtggc caattagctg accttcggta
    16501 ttagctcaaa aaacggcaaa atatgaggag ctatttttat ttggctattc ttattacttg
    16561 atgcagaaca gcttttcaca acctcttttc gtctattttt tattttcgag atttctcttt
    16621 cctttaaaaa caactgtttg aaagaagaac gcacatcctt gaaaaacaag cccgctaacc
    16681 gttacaccta accagccata ctgctgccac attgtcgtcc ctagcaatga accagccgca
    16741 cctccaataa agtacataaa cataaataca
//
LOCUS       DACCVH010000058        16669 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.058, whole genome shotgun sequence.
ACCESSION   DACCVH010000058 DACCVH010000000
VERSION     DACCVH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.058"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1350
                     /locus_tag="IVV98_001986"
     CDS             <1..1350
                     /locus_tag="IVV98_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7807623.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="IVV98_001987"
     CDS             1484..2827
                     /locus_tag="IVV98_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7807624.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="IVV98_001988"
     CDS             2939..4390
                     /locus_tag="IVV98_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP7807625.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="IVV98_001989"
     CDS             4739..5371
                     /locus_tag="IVV98_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAP7807626.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="IVV98_001990"
     CDS             5959..7398
                     /locus_tag="IVV98_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807627.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="IVV98_001991"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="IVV98_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="IVV98_001992"
     CDS             8160..8375
                     /locus_tag="IVV98_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807628.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="IVV98_001993"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="IVV98_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(9035..9946)
                     /locus_tag="IVV98_001994"
     CDS             complement(9035..9946)
                     /locus_tag="IVV98_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7807629.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(9965..10969)
                     /locus_tag="IVV98_001995"
     CDS             complement(9965..10969)
                     /locus_tag="IVV98_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP7807630.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(10966..13089)
                     /locus_tag="IVV98_001996"
     CDS             complement(10966..13089)
                     /locus_tag="IVV98_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7807631.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13094..15541)
                     /locus_tag="IVV98_001997"
     CDS             complement(13094..15541)
                     /locus_tag="IVV98_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7807632.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15528..15917)
                     /locus_tag="IVV98_001998"
     CDS             complement(15528..15917)
                     /locus_tag="IVV98_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7807633.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(15977..16480)
                     /locus_tag="IVV98_001999"
     CDS             complement(15977..16480)
                     /locus_tag="IVV98_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP7807634.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16493..>16669)
                     /locus_tag="IVV98_002000"
     CDS             complement(16493..>16669)
                     /locus_tag="IVV98_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807635.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLSLFNRIVGA"
BASE COUNT         5385 a         3108 c         3069 g         5107 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattcat cacccaccta tagaggatgg gcgacttctg cctgaaataa gttacactac
     9001 ttataacttc taataaaatt agattgagtc attattattt aacatcaacg attttccagt
     9061 ttccattttt ttgtaatact aatttgtact gaaagtagct agtggttttt gatacattat
     9121 caaggtattt tatctttgta ctcactagaa aattttttcc gttttgtaga taaactggat
     9181 tctctaactc cgaaaacttt aagtcaatat tgattggtcg catcgcacca ttttcaacat
     9241 aatactccaa ttctttttca gaagctgatg gataaagttt aaaaaatgtt tctaaaaaat
     9301 cggtgatttc ttccgttgtt ttggcatcaa tttctgaatc gttttctact tgttttgctt
     9361 catattttgc cttgtctggc tttccaatca ttgttggcaa actagttact aaatgattcc
     9421 tgttttcatc ttcaaagatt gtcactcgat atgcagaaga aattgattgc gtcttttttc
     9481 cctctgtaat atgttgctcc actaaaaatg aaacgacaaa ttcttccgag tgtttttcaa
     9541 catctagaat ttttacagat tgaacttcgg aactcgtggg aatatctgct cgaaccatat
     9601 cttggattaa agcgagaccg ttttctgtaa ggtactgttc gagattactc attctctttt
     9661 caattgcttc tttgttattt ttccatgaaa aatattcttt cgcaaaatcc tctgtaaaac
     9721 tttcaacgcc agaagtattc actaccttct cttttataac cactttttca tgagttgtat
     9781 gttgatcaat ggcggtgaaa tttttataaa cgccaaaagc aagactacaa gacaataaaa
     9841 gccaaagggc aagcaccatt tttcgatgct tacccacgga tacaactcgt tcttttttct
     9901 tttttgggct cttttccttt tgattccgtt caatttttat cttcattctt tttcctcttt
     9961 tctcttattt gtatcggcca gctccgataa gatgctgccg ccaatagttt tccgttagat
    10021 tcgtccaccc cactggatct cctgcatgaa acatgcgatt ctcccctgcg taaatgccca
    10081 catgggtcac ataagtaccg gcatcatagg ttgaatgaaa gaaaactaaa tcacctggtt
    10141 tggcatcttt tagatcaata tgagtcatgg catcatattg atcctgagcc acccgaggaa
    10201 gtttcaggtc aactttggca taacaccatt gggtcaagcc actacaatca aaccccgttt
    10261 ctggacttga gccaccaaac acataggccg ttccttcata cttaaatgcc tcatcaaaaa
    10321 tttcttggac tattttgtca tcaaactgag ttgtagttag gtattgcttc actaataaac
    10381 agtaaaacat attgccataa ttataccgcc acccaccatt ttccttaatc gcgattgggt
    10441 tggggtaatc gactttttga ccacctgatt tttcctttga aaaagattca gctaaagcaa
    10501 aactatgctt cttcccgttt ttcccgacat gatctagata cccgccacca tagttatagg
    10561 cctgaataat actatcttga tcacacccta gttctttgga acgcttaacc aaagacgcaa
    10621 aatagagaca gccttgtttg atggatgcct cggtacttaa tgaattaggt ggtaatccgg
    10681 ctgactcaga actttgcata acgtcttcca ttgtgccacc agattccact tgaataatcg
    10741 ccaaaagaat tggaatatac tctgttatat ccgattcttt ggcatacttt tccaccattg
    10801 cacggtgttt caatacttct tctgagacac tagttccgcc aggagaagtg ccagaactac
    10861 catttccctc actgtcttca ccaaacaaca aacccacaca catcaaaata cccataaaag
    10921 agatggtcag aaaagttaat gaaataacac ccactttctt caagttcatt ttttctcacc
    10981 tgaccttgat tttggacgat ggttcattct tttttgtact ttttgattgg tctgctttgg
    11041 cagagtggac ctctgtttca cttgttggaa agaatttttc ttacttgctg attggctttt
    11101 cccttttgaa atgatttctt gactagttag ttttcgtttg atttcgggat tcagatttgc
    11161 tctcacaatc cgctttggtg cttctttttt cagcatcata tctttctgag gttgagctgc
    11221 tttatctatt ggaatattcg cccttctttt tccctgacga tttgttgctt cactcagtat
    11281 cttgcgtttt tcgtccattt tcgcatttct tcgttgtcgt tgtttttctc gcaaatccac
    11341 tcgatccgct ttttcttgga acagtccgcg cttgaattct tctggtgctt ttttcgactt
    11401 ttcgattcct ttatggagat tgtatttcaa attcgttggc gtattcctta cctgatcctt
    11461 tacttgttta gtcttatctt tcaccaaagc ttgggtatcc aaaactttgc cgatttttct
    11521 cccagccaaa ttcattcggg attgtttctt attatttgaa actggattct ccttagttaa
    11581 gtcagatagt atttcgtgat cgttcggtaa tcgtgaattc tttcgtagag aagaaccgga
    11641 tggcttaaat ttggattttg attgttcctt tgccaactta tttccgactg ctgcaccacc
    11701 accaaaagcc aaagctcgtc ccacatttcg attgagttgc cgcaattttc gattcattaa
    11761 catttgcggt tttcgcatga cgcgtcttcc cattgactgg ctatcattac tctggaggtt
    11821 gaacatactc ataatgtcgc ccaatttgaa atagataccg gcaaaggtca caatttgcag
    11881 aaaagcaacc atgaaaaatg gataggttgc cgaaatattg aaaaacatcg tggagatgct
    11941 aaatgcagtc gtaatcacca aagtaacacc cgctcgcatc ataatcgtat tgaataaacg
    12001 aataatcgcc ttctttccta aactttcata agtcggcaac atggacaata agaaactaat
    12061 tggcagaaac atcgcaaaga taatgaagag aatttgcgag aacaacataa tccctgttag
    12121 aagaaaaaca aagaaggaaa tgccaatatt gaacaatacc aaaaagacca cggtccctaa
    12181 acggttcatg gtcttggtaa tactgagatt cgcattgtca ttgtcttcaa tctctgcctt
    12241 gaccgcttct tcccgatctt tgcctttgtt ttcatctgga ctcacagata gaatcttgtt
    12301 gacccggtct tcaccaattt cttctatgtt ggaatcatca aattgcagta gtaaccaagg
    12361 ttgttggact tgaatcgaaa acaaactatc ccgaatcaaa tccacactat cttttccttg
    12421 gctttctgaa ttgggtacaa cgatctcggt tccaagggta agggccgctt cactaacatc
    12481 tgagctaaag tcattgattt ttgtgatata ggtaggcgca taagcaatga acgaacccga
    12541 tagtagaaaa atcatcacaa aattaatcac ggctcgaact gctttcgtgg tttctcgttt
    12601 taataatccg gtatacgcca catacacccc cagagctaaa atcatcaata atagaaaccc
    12661 aaaataaaat ccggaggtct ggagtccatt ttcagtaata ccagccaatg tttggatatt
    12721 ctttccaata ctttcagccg tatccgaaat gaaatctaat ttgtaagcct cttgaaccac
    12781 ataacccgtg gcgttcgaca aatacaaact caccgtccaa atgaaattag taatggcata
    12841 aagaccatac atcacgcttt tccctaagcc atcaccccaa ttccaaggca accaatccca
    12901 agagctatcc acaaagaaat ctagttgata gttgttcagt gaatatttgg aatatagatt
    12961 tcctgcttca actgtatcat caactagccc tgtcgcctcg gctaccgtac caactaaact
    13021 caatagaact atcagagtga gtatgctaat aaaaacgatt cccacaatcc gaaaaagttt
    13081 ctttttcatc ccctcactcc attctctctt gaacaggtgg acgggtatca aaggcatgga
    13141 agagttcttc aaagactgga tgtacctgaa ccacgcctac ccgaccatac aaatcctgca
    13201 tcaagcattg gccattttcc aaatctcgta ggcgtttttg attgctttca tcttctcgat
    13261 ccaagccaaa gaattccaag gttttcttga tttcatgaat atcggtactg cgaaacgcaa
    13321 acttcaaccc gatattattc ttcaagcgtt catccagtaa atcatcacta ttttgcgtga
    13381 caaagtaaac cccggcattc atagcccgcc cagcacgaac gagcttattc gataatgttt
    13441 tcccttgcgc tacttgaaga aaactccacg cctcatctaa gtctacaatt ttgaagattt
    13501 ctcgattact atggataaag tccaaggcaa aagtggaaat gacgattagc atggaaacac
    13561 taagcaattc catggtggta tattcttcaa aagtggtttc tgcatctggt aaaaccaaat
    13621 ccgctacttg aatgatattt aactgcctat ctaaactaat cgactgggta atcgaaccat
    13681 ctgagaaaag caaatgggca aaatcataat cggtaaagga ctcgatgtga tccgcgatat
    13741 tttccgcaac tggtgagcct tcttttcgaa gctcattaat tacttgtaat aatccccgtt
    13801 gattgctttg ggtaaccgtc cgaatggcct tacgcaacac tggaaacttc tccccatctc
    13861 gactagaaat tcctgttaaa aaggtcagaa tatcaattgc tagactttca gaatccttct
    13921 ttttctccat aatcacataa ggatcaagta atccttgatt ttttggctta ctagttaagt
    13981 tgagaatatt gatttcatcc gcaatttctg gcaaggtttc tttccagcca ccccgttccc
    14041 cttttggatc gacaatcaca gcttgtccac caaaaaggac ggcgtaataa actaagagat
    14101 tgttactaaa ggactttccg ccaccgagtg aaccgaggaa tgccgctgct agcgcattgg
    14161 taactgaatc cttgacccct tgtgaggcca atgccggttt caggtaaaca ttgcgccccg
    14221 tatctacgtt ataaccaaag taaatgcctt ccaactcccc taacatctga gtggcgccaa
    14281 aaccaagtcc ggcgagaaaa tcagacgtaa catactggat ataatcattc atgtatcgct
    14341 tactagaagg taagaattct tcatgtagcc ccatcatatc gccaaaaggc cggactagtt
    14401 ttacattggt atcatcataa aaatctagca cttcatcaca ccggcgcttt agttcatcta
    14461 ctgattcggc acttactcga accacatagc tcagtttgta catggattct ttggactgat
    14521 ccaaggtagt ttccaattca tctacggaat ccaatgcatc taagacattg gaatttgttt
    14581 cattgtcaga ttgataggca tggttgtcca agtcttttaa ttcctttttc ttattgcgaa
    14641 cggtagcaag tgcctttttg ttcgtcacaa tctccacatt catactagtg tcaattggga
    14701 atgtaaattg ttgttgctgg taatagaaaa gttctgagga gggaaactcc atttccccca
    14761 caattgtatt aattgttaag tacgctacat atgattcatg attctcatgt tccatgcata
    14821 agtaccgggg cttttcttca atcaaacaac gactgggacg taataagtcg taacgtttca
    14881 ccaaagtttc cgacttcagc tttttctttg gtagctgaaa ttcatattct tcaaatggtg
    14941 tacccttttc gccatagata tgttcaatca aatacatcag atcactcggt gtgactcgtc
    15001 tgactttaaa tcttcgagcc aatttacttt ccattagttt ttcaagcttg gtatatcggc
    15061 gaatttcttc attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga
    15121 caaattcttg aaagccggag aagaaagatt tcttgagatt ctttagattg acctcttcat
    15181 ctgtcgcaat cagtttgaag ccaataaaaa agcgataatc aatctgacta tcgccaatca
    15241 tggatactaa tgcctctgtc tgtaaatcaa ttcgttgttt cgctacttct gttaatcgcc
    15301 cggtaatttc cttttttgat cgttcttgcg tggcacgaat actactttct gtggcaattt
    15361 gtaaggcatg aatcttgcct tcacgatttt gcgcaatcaa ttgacgaaag ttatcgtgga
    15421 cttgatattt ctgttcaggt gacaaaaagg agtaattgta aggtattaac tcatagtagg
    15481 caaaacattc tccctcttga ttaaagacaa gattattttc aatatactta atcgggtaca
    15541 tagttcacac tccttaccag agtaatgggt tcgtcccatc gtttcttctg ttctttgact
    15601 ttctttcctg cgaaagtgac cttaaatcgt aagtgatagc taataaaaga tcgtaaaaat
    15661 cccaatggtt tcttaccgtc aaacgttttt tgcgacatga accaagtaac tgccaccggt
    15721 atacctaagt attttaaaaa ggccccctct atcatagata gtggaggcac atgggcaaat
    15781 acgatgacaa acagcaagga taaaacaaac caagccatct ggttaaaagt cacaggaaaa
    15841 ggcagttgaa agtcattaat tgcataaatg accttttcaa ctgcccaaat actggtgtag
    15901 ctttttattt tcttcatcaa atcattcctt taaaaagaag gatagtttag aaatcaacta
    15961 cccttcaata attttgttaa tatggatact caaaaacacc tcgactcgtt accaaataat
    16021 tgcctccaat ctccaagtct ctaccacacg catcaaaatc aatatacgtc ttcaagtgtt
    16081 ctggtacttc tccaaaatca ccagcttcta caatcaagaa atatgctaca tcactcatat
    16141 catcgcaatc tggataatag ataatatcat ccacatgctc taccatctcc tcaaaagaat
    16201 tgaagaaagc atgttgaatc tcagaagcaa cttcaccaac tggcgttcct tcaagttcct
    16261 ccgctaagcc acacaaccga ttaatttcct caattggcgt atactcatca atctcaaagg
    16321 gaagttcata atcatgaatt gcatattcct cgtattcgtc atttaaccca attcgttctt
    16381 tcacttcatc aaaatcgaca ggtggggtaa accacgcccc caccaattca ccttcgttat
    16441 atttcccgag gttcgcaata taaacacgca tctgttccat cgtgcttccc ccttacgcac
    16501 cgacaattcg gttaaacaaa ctgagtaaga catccttcac cccagaagca ttaaagacca
    16561 atccgaccgc aatcaaagca atcaccaaaa agccaatcag tttggaaaac tcccgcttaa
    16621 atcctaaaaa caaaccaatg accacaattg ccagtaagac taaggattg
//
LOCUS       DACCVH010000059        16211 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.059, whole genome shotgun sequence.
ACCESSION   DACCVH010000059 DACCVH010000000
VERSION     DACCVH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.059"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            226..894
                     /locus_tag="IVV98_002001"
     CDS             226..894
                     /locus_tag="IVV98_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP7807636.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="IVV98_002002"
     CDS             complement(1094..1324)
                     /locus_tag="IVV98_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807637.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="IVV98_002003"
     CDS             complement(1451..2833)
                     /locus_tag="IVV98_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP7807638.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="IVV98_002004"
     CDS             complement(2989..4176)
                     /locus_tag="IVV98_002004"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP7807639.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="IVV98_002005"
     CDS             complement(4183..5214)
                     /locus_tag="IVV98_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7807640.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="IVV98_002006"
     CDS             complement(5260..6684)
                     /locus_tag="IVV98_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807641.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="IVV98_002007"
     CDS             6859..7764
                     /locus_tag="IVV98_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7807642.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="IVV98_002008"
     CDS             7855..8532
                     /locus_tag="IVV98_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP7807643.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8813..9709
                     /locus_tag="IVV98_002009"
     CDS             8813..9709
                     /locus_tag="IVV98_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7807644.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="IVV98_002010"
     CDS             complement(9764..11134)
                     /locus_tag="IVV98_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7807645.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="IVV98_002011"
     CDS             11372..12118
                     /locus_tag="IVV98_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7807646.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="IVV98_002012"
     CDS             12115..12954
                     /locus_tag="IVV98_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7807647.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="IVV98_002013"
     CDS             12955..13905
                     /locus_tag="IVV98_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP7807648.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="IVV98_002014"
     CDS             14046..14798
                     /locus_tag="IVV98_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807649.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="IVV98_002015"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="IVV98_002015"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP7807650.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5267 a         3017 c         3250 g         4677 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt tacatttttt taagagaatt tgataaaaat caaaaatttt
    16081 tttgcttttt tttatggatt attgcagtga atgttacaga atctgcgttt ttcattcaaa
    16141 aataaaaaaa catagaaaaa cgattacttt gcttatacaa caaggctttt atggttttgt
    16201 atcaaaaaaa t
//
LOCUS       DACCVH010000060        15900 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.060, whole genome shotgun sequence.
ACCESSION   DACCVH010000060 DACCVH010000000
VERSION     DACCVH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.060"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(52..522)
                     /locus_tag="IVV98_002016"
     CDS             complement(52..522)
                     /locus_tag="IVV98_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP7807651.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="IVV98_002017"
     CDS             complement(681..1139)
                     /locus_tag="IVV98_002017"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP7807652.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="IVV98_002018"
     CDS             complement(1310..2455)
                     /locus_tag="IVV98_002018"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP7807653.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="IVV98_002019"
     CDS             complement(2468..3385)
                     /locus_tag="IVV98_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP7807654.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="IVV98_002020"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="IVV98_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP7807655.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4862..6121
                     /gene="lysA"
                     /locus_tag="IVV98_002021"
     CDS             4862..6121
                     /gene="lysA"
                     /locus_tag="IVV98_002021"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP7807656.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6108..6908
                     /gene="dapF"
                     /locus_tag="IVV98_002022"
     CDS             6108..6908
                     /gene="dapF"
                     /locus_tag="IVV98_002022"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP7807657.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6911..7792
                     /locus_tag="IVV98_002023"
     CDS             6911..7792
                     /locus_tag="IVV98_002023"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP7807658.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7789..8505
                     /locus_tag="IVV98_002024"
     CDS             7789..8505
                     /locus_tag="IVV98_002024"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP7807659.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8511..9206
                     /gene="dapD"
                     /locus_tag="IVV98_002025"
     CDS             8511..9206
                     /gene="dapD"
                     /locus_tag="IVV98_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP7807660.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9222..10223
                     /locus_tag="IVV98_002026"
     CDS             9222..10223
                     /locus_tag="IVV98_002026"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP7807661.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10220..11581
                     /locus_tag="IVV98_002027"
     CDS             10220..11581
                     /locus_tag="IVV98_002027"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP7807662.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11541..12692
                     /locus_tag="IVV98_002028"
     CDS             11541..12692
                     /locus_tag="IVV98_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP7807663.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12667..13836
                     /locus_tag="IVV98_002029"
     CDS             12667..13836
                     /locus_tag="IVV98_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7807664.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14011..15390
                     /locus_tag="IVV98_002030"
     CDS             14011..15390
                     /locus_tag="IVV98_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7807665.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15671..15900
                     /locus_tag="IVV98_002031"
                     /pseudo
     CDS             15671..15900
                     /locus_tag="IVV98_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5202 a         2803 c         3384 g         4511 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc gaactattcc gaactatatt
     4621 gaagcgaaaa tattttttca tcactaaata gtgttgaatt tatgttttta tgtataaata
     4681 gcttctaata gttcgggtat tttgttttta taaccatttt tattcttatt tttaaaaaaa
     4741 tatttcgaaa tatactagac aattcagaaa attttgttta atattattcc aataaaattc
     4801 aaatctttat caaatgaaat tccaataaaa acggaaaaaa agtgaaaaga ggaatgaaaa
     4861 aatgacagaa ttgataattg gcggagtcac agcaagcaca ttggcagaaa agtataagac
     4921 acctctgtat gtgtatgatg aagaaaagat gagacaaacg atgctgtcat tcaagcgagg
     4981 ctttgtatcg aaacgttttg atacaaaagt gctttacgcc tctaaagcat tccaaacgat
     5041 tgagatgctg catttagttc gtgaatatgg attcgggcta gatgttgtca gtggtgggga
     5101 aatctatacc gctttgcaag ctgattttcc tagagatact atctacttcc atggtaacaa
     5161 caagacgcca gaggaactga tctatgcact tgaaaatgat ttgttgcata ttgttgccga
     5221 taatttgatg gaagttgaat tattagcaga attaagccaa cgctatttaa aaaaaatctg
     5281 tatcatgctt cggttgaatg tcggagtaga agcacatact catgaatata tcgtcactgc
     5341 gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa gagtgccaac aagcccttca
     5401 gttgataaaa gaaagcagct atctagagtt agaaggattt catgctcata tcgggtcaca
     5461 aatttttgat gttactgctt ggttagctga aatcgacaaa ttgacgaatt acttaaccga
     5521 ttttgaccaa cctctttcct tgaatcttgg cggagggttt gggattcgtt atacacaaaa
     5581 tgatcagccg atcccagtcg aagaggcact aaaaaaactg attgaatata cggaagaagc
     5641 tttggaaaaa cgaaaactga ccattcgtca attactgatc gaaccgggta gaagtattgt
     5701 tggagaagct ggtacaacac tatacacgat tggtttcatc aaaaagacac cacataaaaa
     5761 atattacttt gtagatggcg ggatgacaga taatatccgt ccagctctgt atcaggcaga
     5821 atacgattgt gatttagcag caaaactgtc ggaagaaaaa acagagaaag tgacgattgc
     5881 aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa gcttatttgc cgaaagcaga
     5941 atcgggtgat cttttagctg tttattccac gggagcttat ggatactcga tgagcagcaa
     6001 ctacaatcga gcgacacgac cagcagttgt ttttgtcaat aatggccaat caagactgat
     6061 tgttcgcaga caagcatttt ctgatctact aaggggggaa gtttcctatg atccttcata
     6121 aatataatgg ctgcggaaat gattttatct tattagatta cgcagaagac acagattata
     6181 gtcaattagc cgcttcttta tgcacaaaag aaaaatatga tatagacgga ttgatcgccg
     6241 taaaaatcga tccgttggaa atgatctatt acaacaaaga tggcagccgc gcgccgatgt
     6301 gcggaaatgg cattcgctgt tttgctcgat acgtaaatga tcagaacatg atgaatgaac
     6361 aggaattcaa cgtagagaca ttagcaggca caagaaaaat tacggtgttg gatccctcac
     6421 ctttttattg cagcgtagat atgggagtgc cagatgattc tccggaaaaa atcaaagcta
     6481 atcaaactta tccaataaaa aaccaggaaa tagagatcaa tggtgaaaaa gtaacgatca
     6541 ctagtttatt tttaggaacg attcataccg ttgtttttgt tgaaaatgcg cgtgaggaag
     6601 tctggagaaa aagaggtgaa ctgatctgtc atcatccttt gttcaaagaa aaaaccaatg
     6661 tcaactttgt agaagtagtc aatgaacaag aattgatcgt ccgtacctat gaaagaggag
     6721 taggttggac acttgcttgc ggtacaggtt gctgtgcctc ttatgtggtt gctaaggaaa
     6781 ctgggaaaat ttcagcagat caggtagttg ttcacttgga acaaggagac ttgatgatct
     6841 ctggtgagga tgcgatacaa atggctggcc cagcagttca tgaatggaca agaatattgg
     6901 aggaatgaag atgataaaag gttcgatcgt ggcgctgatc acgccgatga atgaagaggg
     6961 atcagtagat tatgctggtt tggaaaaatt gatccaattc catttagatg aacaaacaga
     7021 tggattatta gttttaggta caacaggaga atcttctacg ctcacacaat ctgaggagga
     7081 gcagatcctt caactgacag taaagaaagt ggctggccgt gtgccggtga ttgcaggagc
     7141 tggaacgaat aatacgaaag aaacgattga aaaagcgaag cattttgctt ctttgggggc
     7201 agacgcactt ttggtcatca ccccttacta caacaaaaca agtgatgcag gactagctgc
     7261 tcattttaca gcaattgcag aagcctcacc gattccgctt attttgtata atgttccttc
     7321 tagaacaggc atgtcgattc caatccatgt attagtaaat ttagcagaac atcctaatat
     7381 cattggtttg aaagaagcct caggagatat ggcttatgtg atggatgccg ctcggttgat
     7441 tggagaagaa ttcttccttt acagtggaaa tgatgatttg atcctaccag taatgagtgt
     7501 aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa cctaaaatag tccatgaatt
     7561 agtaaaagat acgcaggacg gaagatggca gcaagcaaaa gaaaagcaat taaatgcact
     7621 tgaactgatc catgccttgt tcagtgagac caatcctatt cctgtcaaag cagccatgtc
     7681 attattagac ttaccttccg gacctctacg cctgccttta gtttctcttt caaaagagaa
     7741 aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg gttgaaaaat gaaaatcgga
     7801 ctgattggca gtggacagat gggaaataga gtcgaagaag ttgcacaaga aagaggagat
     7861 acggtccttc ttttacggac ggcacctaaa gaagcaacta cgcttgcttt tacggaactg
     7921 ccagaactgc ttattgattt ttctcatcca gataatttag agaaaatcct ttcgtatagc
     7981 ttatcatatc aacttccgtt agtcattggc acgacaggtt atacacaatc acagttccaa
     8041 gaaataaaag aacatgccaa acatgtacct gtgatgtata gtgctaattt ttcgttcggc
     8101 atcatggtga tgaatcaact aatcaagcaa gcagctgcaa tgttgcaagg ctggcagatc
     8161 gaactgattg aaaaacatca tagtcgtaaa aaagatgcac catctggtac tgcaaatatg
     8221 ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg tatacaactg gcaagggaaa
     8281 aaaagagaag aaaaccaaat tggtgtacac agtattcgtg caggttcttt acctggtgaa
     8341 catgatgtat tgtttgctgc tactgatgaa atatttacga tcaaacatga atctttttct
     8401 aatcgaatct ttgctgcagg cgcagtagaa gcagcggact ggttgaaaga tcagtcacca
     8461 ggttattaca aattagaaga tttattaatg gacaaagggg tgtaaaaaac gtggaagctc
     8521 aagaaatcat ccgctacatt caaacggcat ctaaaaagac gcctgtgaaa gtctatctga
     8581 atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt tggtgaagga agcagcttcg
     8641 ttgtttttgg tgactatgag acgattgctc cggttttaga agctgaatca gaaaaaatca
     8701 ttgaaatcga aatcgaaact gctgcaagat acagcgcagt tcctttgcta gatattaaaa
     8761 aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga tcaagtgtca atcggcaaca
     8821 atgccgtgat catgatggga gcgattatca atattggtgc agtaatcggt gaaaacacga
     8881 tgattgatat gggtgctgtc ttaggtggac gagcgacagt gggcaaaaac tgccatattg
     8941 gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc ggccaaaccg gttatcgtag
     9001 aagacggcgt actggtaggt gcgaatgcag tgattgttga aggtgtccat atcggaaaag
     9061 atgcagtcgt ggcagcagga gcagtggttt tagaagatgt ggcagcagaa actgttgtcg
     9121 gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca gacaaaagaa aatacagcat
     9181 tgattgctgc gttacgcgaa ttatagagga gatggagaaa aatgcgcgaa atagatacct
     9241 gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct caaagtgtta gaagaatatg
     9301 attttccagt aggacgattg aaattattag cttcaaaacg ttcagccggt aaagtttgtg
     9361 tattcaagaa aaagaaacac actgtacagg aattgacaga aacttcattt gaaggatatg
     9421 atttagcgct attttctgca ggtgcttctg tatccaaaga gtttgcgcca atcgcacgaa
     9481 gtcagggact atttgtcata gataattcct cagcatggcg ggaagattcg gatattccat
     9541 taatcgttcc agaggtcaat ctggaagact atacattgaa tcggctgatt gcaaatccaa
     9601 attgttcaac cattcaagcg gtacttccgc ttaaagcttt acaagaagcc tttggtatcc
     9661 agcgagtcaa ttattcgacc tatcaagcag tttctggttc cgggcaaaaa ggcattgaag
     9721 atcttcatcg tacgcaaaat gacgaggaac cagttttgta tccttataat attagccaaa
     9781 cggtgattcc ggaaatcgat cagcctttgg aaaatgggta tacaaaagaa gaacagaaaa
     9841 tgataaatga gacccgtaag attctgcatc agcctgcttt gccagtatca gcaacctgcg
     9901 tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc agttcaactg caaaaagagt
     9961 ttacgacgga agaaattaga gagtgtctca gccagtttcc agggattcaa ttagaagatg
    10021 atctagcagc acataaatat ccgacgagca ttcttgctag aggaacagat atggtttatg
    10081 ttgggaggat cagaaaagac acttctttag agaacggatt gttgttctat acgactgccg
    10141 ataacatacg caaaggagcc gctgcgaatg ccgtacagat tgctgcagct ttaatgcaga
    10201 aaatagcgga ggtggcaaga tgagtaatac gctgaaagta gcgaaattcg gcggaacatc
    10261 gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt gttctttcag atcccaatcg
    10321 ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca gatgatgaca aagtaacaga
    10381 cttactttat ttgatttatg cttaccttca gcatcatgtt gattggacac ccctttggaa
    10441 aaggatttgt gatcgtttca ttcaagtaag agatgttctt gccctgcagt tacctattga
    10501 agatgaacta gcacgcatac agaaacaact ggaagacgaa aagataactg aagattattt
    10561 agtaagtaga ggtgaatatc tgactgctca actgatggct gagtatcttg gttaccagtt
    10621 tattgacgca aaagacctga ttttctttga ctatgatggg aaaatcgatc aggaaaaaac
    10681 agcacaggaa atcacaaaag catttaaaag atatccgaaa atggttgttc cagggtttta
    10741 cggggcgaac cctgcaggaa aagaaaaatt attgggccgt gggggaagcg acattaccgg
    10801 cgcgatactg gcgaagatgt tgcaagcgga aagttatgag aattggacgg atgtttcagg
    10861 aatcatgatg gctgatccgc gaatcatcga tcatcctaaa atcatcgagg aaatctcttt
    10921 tagagaactg agagagatgg cttatatggg ggctaacgtt cttcatgaag cagctgtttt
    10981 cccagttcaa gaggctgata tccccatcca aataaaaaat accaatgatc ctttcgctca
    11041 agggacaaaa atatcgaatc acgaaataga aaaggaaaat ggactgacag gaatagctgg
    11101 acgcaaggat tttctttcca tcactttatt caaacgtcat atgtccgatg aaatcgggtt
    11161 tatctggaaa gcaatgagca tttttgctaa acatgagata tcaatcgaac atattccttc
    11221 agggatcgac aatatcggag tgatcgtctc agcagaagcg attgccgata agttatttct
    11281 catcacgaaa gaattaaaag aaacacttgg cgtggaagaa atcgtcgtga tcgaagactt
    11341 agctttgatc tctgtcgttg ggggtccgca taaagaattg attggattat ctgggaaagt
    11401 gttatcgata ttgaacaaat tagaaattcg cacatcgatc ttatcacaag gagcacagga
    11461 gttgaatctg atcatcggtg taccgaataa tcaatatgaa acagtagtga agggtatcta
    11521 tgaagggatg gtgaatacgg atgctgaaag aatatcgaat ggcactccat caaattcctg
    11581 aaatcgggtt tcatgaattc aagacaaaaa aatatttata tgaacaagta aaaaacagcg
    11641 aggccgttat ccatgaaatc ggcgaaacag gactactcct ttattttgat aatcagcaag
    11701 aagaaacgat tgcttttcga acagatatcg atgcactgcc agtcaaagaa gaaacgaatc
    11761 tctcttttgc ttctaagcat gaaggttata tgcatgcatg tggtcatgac ggacatatgg
    11821 cgatgctttt agggttgact gactttataa ctaaacacat tgaggatctt atttataatg
    11881 tagtactgat ctatcagcca tcagaagaaa tttccggtgg cgcacaaagc gttattcagt
    11941 caggattgtt ggataaatat gaagtacaag caatatttgg ctttcatcta tggcctggac
    12001 tagctaaggg agaagttttc tctcgaccag gacctttgat ggcacaaagc agtgaaacag
    12061 acattatcat taaaggccag tctgcacata ttgcttctag tgaaaaagga atcgatagtc
    12121 tggaggcagc tgtacgattt ttgaagaatg tttatgattt tgaccggcaa ttaccggcag
    12181 agtggaatca tctaatgaaa tttggccaaa tccaaggtgg aacgatccga aatgttttag
    12241 ctggagaagt tattgtatcc ggaagtatcc gttcttacag ttcagatatg caaaattatt
    12301 tgaagagggg attagaccat ttagcagaac agtttcactc tacagctact atttcttttc
    12361 gctataatga cggctatcca gctgtaatca accatagagg cttatatgca gcactgttag
    12421 attcaaacaa actacatgaa ttagatgctc cagttcttca agccgaagat tttggcatat
    12481 atacgcaaca atatccatgt gtatttttct ttttaggtgt cggtgatacc cctgctttac
    12541 atgatccgac gttcgatttt gatatggatg ttttagaaaa tggtgtagaa tggtacaaaa
    12601 cgattctttt tacagaaaat cttcttgtaa aaatcgatag cagttcaaaa gaggagcgag
    12661 taaataatga tgaatttatc caatcgattt agtcctaggc tttctagaat agaagtatca
    12721 aaaatacgac aattcgatca gcaaatatcg tcgataccag atgtgatcaa actcaccctg
    12781 ggagaaccgg attttccaac tcctgaacat gtcaagcaag caggaatagc agcgattgaa
    12841 gaagactttt ctcactatac cggaatgaga ggattagagg aactgcggga agcggcttgt
    12901 atatttcagc aacagcgtta tggattaact tatgatccgc aaacggaagt tttgacgaca
    12961 gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg ttttggaaga aggagacaag
    13021 gttcttattc cagcgcctgc ttattcagga tatcagccat tagtggaact agctggtgct
    13081 gaattgatcc cgatagatac ttctgacaca gggtttgtct gtcagccgga acaatttgaa
    13141 cgagcatttg aacaatatgg atcagctgtc aaagcagtca ttttaaacta tcctaacaat
    13201 cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa tcgctgaggt tttaaaaaaa
    13261 tatccggtat ttgttataag tgatgaagta tatgctgaat tgacttatag tggaacgcat
    13321 atgtccatag ctacttatct tccagaacaa acaatcgtga taagcgggtt atccaagtca
    13381 catgcgatga ctggttggcg agtgggcttt atttttgctc aaaaagccct tattgacgaa
    13441 ctaattaaag tccatcaata tctggtgact gccgctacaa cgatgtcgca aaaagctgcg
    13501 gctgaagcgc taataaatgg ggtgaaagat agcgagaata tgaaagagca atatcaaaca
    13561 cgaagagact atctggtcca gcaattggcg cctttaggat ttgaagtgac ccagccaaac
    13621 ggtgcatttt acttgttttg caaactccca gctgccattc aaactgactc ttggcagttt
    13681 tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc caggaattgc atttggccca
    13741 gaaggagaag gttatatccg gatttcttat gctagcagca tggaaaaatt acatgaggcc
    13801 tgcaaacgga tcaaagactt tttaacagaa cagtgattca tagattttat caaaaaaaca
    13861 atcgttaatt ttgcggtata ttctgcaagg agacgattgt tttttaaatt tagttcaaat
    13921 gaacgcgttt cttttgattc ataactaatg taatgttaag tttaaattgt ttagaatgat
    13981 tttaaaagaa tattcaagga ggtttcatca atggaaaaaa tcaaagttgt cattgtaggt
    14041 gcatctcatg gagggcatca atcgatcttg gaactattga cacgatacgg tgaaaatgta
    14101 gatatcacgc tatttgaagc aggagactat atttccttca tgtcatgtgg tatggagctg
    14161 tatttagaag acaaggtaac agatgtaaat gatgtacgta atttcagacc agaaaacttt
    14221 ccgcaatcca atgttcatat tttaaataat cacgaagtaa aaacgatcga tgccgataaa
    14281 aaaacagtaa cggttactag cgcatcagat aacgaaacaa aagaatatcc ttatgacaaa
    14341 ttgattttga gttctggtgt caaaccaaac aatctgccag taccaggagc agatctagaa
    14401 aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa tcaaagaaaa attaaatgat
    14461 ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca ttgggatcga agcagcagaa
    14521 gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg tgatcgatag acctttaggc
    14581 acttatttag atgctgagat gacagatatt ttagaacaac acctaaatga aaacggtatt
    14641 gaagttttga caaatgcaaa aatcgaagct tttactggta acggaaaagt tgaggcaatc
    14701 aaaacaagtg aaaaagaaat cccagcagat ctagtcattc aagctgccgg tgtgaaggca
    14761 aatacagaat ggttaaaagg gatcgtcgac ttagatgaac gtggctggat ccaaacaaat
    14821 gaatacttgc aaacgaatct tccagatgtg tatgcagtag gagatgctac acttgcttat
    14881 tctatcccag cacgcaaaaa aatgccgatc gctttagcga ctgttgcacg tagagaagca
    14941 cgttatgtag taaaacatct ttttgaagaa gtaccaaaca aaccgttcgg cggagtcgta
    15001 ggttcctctg cattaagtgt ctttgactat cattttgcag caagcggatt gaatagcttt
    15061 acagcagcaa aagcaggagt agatgtacga gtgtcttatt atgaagatac gttacgacca
    15121 aaatatgtac cagaagaaca aggaaatcca aaagtgtcca tccaattatt ctcggatcca
    15181 atgacccatc aattgctagg aggagcagta ttatctacct atgatgttac aggtcaagga
    15241 aatgtattgg cactagcgat ccaaaacaaa ctgactttag aagaactagc agaagctgac
    15301 ttcttcttcc agccaggctt tgaccgacaa tggagcatgt tgaatctagc cgctcaacaa
    15361 gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa tatttgaaaa gaggttgtga
    15421 aaaagctgcc ttgcatcaag taataagaac agccaagtaa aaacagcttc ttatgttttt
    15481 aacttggctg gacttattac cgcagatgca agcttttgaa caccgtttat tttcaaaaaa
    15541 gggactgtga cacgatttgt gtaccgaccc ccaaaagtta gaccaaaaaa tctaactttt
    15601 ggaggtcggt attttttatg gttaaatata cttttgaact taaattaaag atcgttcatg
    15661 attatttgga tggcaaaggc gattggaccg taaaaatcca gatcaagaga ttgaagcgga
    15721 aatgcttaaa attcgggaga agcacaagga ttatggctgt ttacggatga ccaatgaact
    15781 aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag cgcttgatca agaagctagg
    15841 aataaaagta acggcataca cgcgtaaatc acgtcgctac aattcttatc gaggaaaagt
//
LOCUS       DACCVH010000061        15675 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.061, whole genome shotgun sequence.
ACCESSION   DACCVH010000061 DACCVH010000000
VERSION     DACCVH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.061"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..132)
                     /locus_tag="IVV98_002032"
     CDS             complement(<1..132)
                     /locus_tag="IVV98_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7807666.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            541..2913
                     /locus_tag="IVV98_002033"
     CDS             541..2913
                     /locus_tag="IVV98_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807667.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2974..4434
                     /locus_tag="IVV98_002034"
     CDS             2974..4434
                     /locus_tag="IVV98_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP7807668.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            4445..6649
                     /gene="topB"
                     /locus_tag="IVV98_002035"
     CDS             4445..6649
                     /gene="topB"
                     /locus_tag="IVV98_002035"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7807669.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6889..7482
                     /locus_tag="IVV98_002036"
     CDS             6889..7482
                     /locus_tag="IVV98_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAP7807670.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            7495..8394
                     /locus_tag="IVV98_002037"
     CDS             7495..8394
                     /locus_tag="IVV98_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP7807671.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            8397..8894
                     /gene="ssb"
                     /locus_tag="IVV98_002038"
     CDS             8397..8894
                     /gene="ssb"
                     /locus_tag="IVV98_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP7807672.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            9260..9520
                     /locus_tag="IVV98_002039"
     CDS             9260..9520
                     /locus_tag="IVV98_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807673.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9965..10171
                     /locus_tag="IVV98_002040"
     CDS             9965..10171
                     /locus_tag="IVV98_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP7807674.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            10219..10422
                     /locus_tag="IVV98_002041"
     CDS             10219..10422
                     /locus_tag="IVV98_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807675.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            10438..10875
                     /locus_tag="IVV98_002042"
     CDS             10438..10875
                     /locus_tag="IVV98_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807676.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10868..11575
                     /locus_tag="IVV98_002043"
     CDS             10868..11575
                     /locus_tag="IVV98_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807677.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11955..12134
                     /locus_tag="IVV98_002044"
     CDS             11955..12134
                     /locus_tag="IVV98_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807678.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            12459..12722
                     /locus_tag="IVV98_002045"
     CDS             12459..12722
                     /locus_tag="IVV98_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAP7807679.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12716..13066
                     /locus_tag="IVV98_002046"
     CDS             12716..13066
                     /locus_tag="IVV98_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7807680.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(13090..13704)
                     /locus_tag="IVV98_002047"
     CDS             complement(13090..13704)
                     /locus_tag="IVV98_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807681.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            14018..14440
                     /locus_tag="IVV98_002048"
     CDS             14018..14440
                     /locus_tag="IVV98_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807682.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            14450..14653
                     /locus_tag="IVV98_002049"
     CDS             14450..14653
                     /locus_tag="IVV98_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807683.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14864..15448
                     /locus_tag="IVV98_002050"
     CDS             14864..15448
                     /locus_tag="IVV98_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807684.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5765 a         2546 c         3160 g         4204 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaaagaac
      541 atggcagaag aaaaagaacc actagacaat agtcgtttgg gaaaatccaa aagaaaacta
      601 gtacgattgc aaaatgaatt aaacgaacaa attgaaaaga tgtttgaaca ccaaaaaatg
      661 acgaacggtc aaccaatgaa cgacaagagg aatggccgtt catggtttaa ccagcaagaa
      721 cgaatcgaaa ataaagtcca aagtctgaga gaagagatca agcaacaaga agaatacgtg
      781 gaaaagcttg aaagacaaga agagctaaag gaaatgggct ataacaagta cggcggactg
      841 gatatgacga tcgataatat tccaagaatc aaagaagaaa tcgaacgctt tgaaaaaggt
      901 gaatcggctt tttcagccgc cacgatccga aaataccaac ggaagttgga aacattagaa
      961 cagctgaaag aaaaatcaga aaaaggaaaa gaaaatatcc tccctgaagt acaagcgatc
     1021 attgacagcg gacgagtgac gcaatggaaa aaaaatccaa ccatttattt tttgaaaggc
     1081 tatcgaaaag ttgctttaga actgaatgaa aacgggggat ttgaggaatc aaaaaaatac
     1141 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctagacca
     1201 actgattcta tgaaggagaa agaaaacgat catttctatc gagtagaatt caacgaaaat
     1261 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
     1321 caactcaaaa cattggataa ccaatacgcc gcagaagcag gttattataa attctatttt
     1381 gaggaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
     1441 aacagtaatc aaccaatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
     1501 gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1561 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1621 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atacccattc tcctgaagac
     1681 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1741 ttgattgagg aacaatttcc aggtgcaacg gcttgtttag gtcgtgccgc gttgaaaaaa
     1801 gaaggaatct atatcaaaaa aggggaacaa gggaacaaga tctttgtcag aaaaacggtc
     1861 aaagggtttt atgagaaagg acgtggcttt gttcgagaaa cagaagctac accagaagat
     1921 aaaaaacgaa tcgaaagtgg tcaaatcgaa gtgatcaaaa aaccttacta tacgattgaa
     1981 aaagtgtttg atatcacaca aacacagtta aaacctgaag actatccgaa aatctttccg
     2041 aaccgtgtct ttgattttca attggataaa aaaggacagt cagaacttca agctgggatt
     2101 caagcggtag ccaacaatat tggaatacaa attcgagata tgacagaaag tgaagtctat
     2161 caaagagaat taggacaagc acgtggggcg tatgttcgta acgaatttac tggcgaagaa
     2221 gaaatcgtca tgaatactcg aaatactcct acgcagcatt tagctacaag tattcatgaa
     2281 ttagcccatg caagaatgca caaattttca gaattagata ccgcaactaa agaattgcag
     2341 gcagaaatga cttcttatat tgtgtgcaaa cattttggaa tggacacgtc ggagaaagct
     2401 attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa ggaagctgcg
     2461 gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat tcaaaccatt
     2521 tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc agaagtgaag
     2581 caggagcata aaaatacttt agaaacgcca gagaataaga atattgtgcc cgttggttca
     2641 ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg aacgttacat
     2701 ttgaaggatg cggcgtttat tgaagatccg cagcataatc aagtaatttt aaaaggaaaa
     2761 agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct aggaaatcca
     2821 ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga aatctattat
     2881 gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact atctgaaaaa
     2941 cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat gagtcttatt
     3001 gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat ggctgtagtc
     3061 aataaaggac gagattatcg cttagaagac catgattcat ttgtttttga tcgaagaaaa
     3121 caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt agctaaactt
     3181 tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc cactgatttt
     3241 attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga aacagaaaag
     3301 tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa ttatctgaag
     3361 gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg gttgattgcc
     3421 gaactaaagc caaaatatga acggcaaaat ttcttagttc gagacgatcg tttagatcat
     3481 gcggtcgcct ttttatggaa agatccacag acaaaagaga cagtaggggc gagttatcaa
     3541 ggaacgttca ttgattatga acgttttggt gagagaggca catataagca tatagataaa
     3601 aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca gataaaattt
     3661 tttgagagta gtattgattt acttagctat gctgcactga atcgtgatca gttaaacgat
     3721 acgtggttag tctctatgga agggttaaaa caccatgtga tcagtcatta ttttggtgag
     3781 gcagtatctg aattgagaaa gaaacaagcc tttcctcaat ccatcgagat ttgtgtggat
     3841 aatgaccgtg caggacatat tttctacgaa aaagaacaat taatgggcgc agtcgatcca
     3901 tttacgaatc agaaagtacg ttgtgaacga ggaatcgcta atgattggca agtgccaaaa
     3961 gaatacaaaa tcatttatga agaagtcgca aaagaagaaa aggtcacacc agaagctatt
     4021 atggccatac acaagacaga aaacaatctg caattaacga accaactggt ttccgctcac
     4081 aaagtaaatg cgttttttgg ccagcagctt tctgttaacg attcaataga agccattaat
     4141 ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag tttgtgaacg cgtggatggt
     4201 acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgcgca gattcttttc
     4261 tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga atttgtacct
     4321 gaagtaaaaa aggactggaa cgatcaattg aagcatgaga tccagcaaca agaaatcaga
     4381 aagcaaaaac gtgccatgtt gtttcaacaa ggcagacaac aagaaaggga gtgaaatcgt
     4441 catgatgaaa accgttattt tagcagaaaa gccgtcacaa gcgaaagctt atgccgatag
     4501 cttctctaaa gccactcgaa aagacgggta ttttgaaatc caagatcgat tgtttcctgg
     4561 tgaaactgtg atcacgtatg gttttggtca tttagtcgaa ttagattcgc ccgatatgta
     4621 cgatgaaaat tggaaacaat ggtcattaga acatttgcct attttcccta cacattatca
     4681 ctatcatgtt cctaaagata agaaaaagca attcaaggtg gtgaaacagc aacttcaatc
     4741 ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga tcgcttggac
     4801 gatcattcaa caagtaggcg ccgatcaagg aaaaaccttt aaaagacttt ggatcaactc
     4861 cttagaaaaa gaagccattt atcagggatt ccagcagtta cgagacgcaa aagagaccta
     4921 tccaaaattt gaagaagcac aagcacgtca gatcgccgat tggttaattg ggatgaacgg
     4981 tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagct tttccttagg
     5041 cagagtccaa accccaacgc tttacatgat ttatcaattg caggaaaaga ttagaaattt
     5101 caagaaagaa ccttattttg aaggaaaatc cgaagtaatc gctcaaaatg gcgcatttga
     5161 tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag attatttaaa
     5221 agaaaagggg gttcaattgg gaaaacagcc aggcatgatt cgccaagttg aaaccgagaa
     5281 aaaaagcgcg gcaagtccac gtcttttttc tctatccagc cttcagtcta aaatgaatca
     5341 gctcatgaaa gctagtgcca aagacacttt ggaagccatg caaggcttgt atgaagggaa
     5401 atatctaagc tatccgcgaa cggatacccc ttacattacg gaaggggaat atgcgtatct
     5461 gttggatcac ttagacgaat acaagcattt tttgagggct gaagaaattt cgactcctat
     5521 tcatacaccg aatagtaggt acgtgaacaa caagaaagtc caggaacatt acgcaatcat
     5581 tcctacaaaa acagttatga cagaagcgac gtatgaaagt ctgacacctt tacaacaagc
     5641 gatttacgag caagttttaa aaacgacagt ggcgatgttt gcggaaaaat atacctatga
     5701 agaaacaacg atcttgacgc aagtccagca gcttcagtta aaggcaatcg gaaaagtacc
     5761 gatagatcta ggttggaaga agttatttgg caaagagagc gacggaaaag agaaggaaga
     5821 agagccgcta cttcctaaag tgacaaaagg agaaatggtg acggtagatc tacaagtcct
     5881 tgaaaaagaa accaagccac cacaacctta taccgaaggt acgttgatca ctgcgatgaa
     5941 aacagctggg aaaaccgtgg atagtgaaga agcgcaatcc atattgaaag aagtggaagg
     6001 aatcggtaca gaagcgacac gggcgaatat tattgaaacc ttgaaacaaa aggaatatat
     6061 caaggtagag aaaaataagc ttgtggtgac gaataaaggg gttttgcttt gccaagctgt
     6121 ggaaaaagag ccgctgctta cgagtgccga aatgaccgcc aaatgggaaa gctacttgtt
     6181 aaagattgga gaacgaaaag gaacacaaac cacttttcta gccaatatcc aaaagtttgt
     6241 ctctcactta ttggaagtcg tcccaggaca aatccaatcc attgattttg gatcgacgtt
     6301 acaagaagtg aaagcagcca gtgaaaagca agaagccgcg cgtcatttag gaatttgtcc
     6361 aaaatgccag gaacaagaag tcttactcta tcaaaaggtg gcagcttgta cgtctgaagc
     6421 ctgtgatttt aaattatgga caacgattgc caaaaagaaa ctcacagcga cacagctgaa
     6481 ggagattatt caaaatagcc gaacaagcca accagtgaaa gggttaaaag gtcagaaggg
     6541 ttcgtttgaa gcaacgattg ttttaaaaga agacttcact acaggctttg aattttctga
     6601 aaagaaaaaa acgaacttca agaaaagaac acgacgcacg acaaaataat ggagggttaa
     6661 tcttatgcgt aatacaacac acaaacaaca agaaatcgaa aatcaaaaag ccaaaattcg
     6721 ttcagaacaa gagaaattac gtgccagtaa aagaagactt cagcaattaa agaaccagca
     6781 acggattcaa aaagaaatcg aattagatcg atagacatta accttgttac aaatacacta
     6841 tcatgatata tttaatgtag tgtatttgta acaaaagggg ggaagtaaat gcaagagaaa
     6901 ctgaaagaat tgttggctat tcgcgatgga aatttatcta tgaaggaagc cagaaaatta
     6961 ggaatcgcag caaccactgt acaaagattg gtgaatcaag gaaaattgat caaagttgat
     7021 cgtggttatt atgtagagga tggtcatgga atagatgatt tattttggct tcagcaacgt
     7081 ttttccaggg gaatcttctc tcatgaaacg actttagata tttaccagct ttctacgaat
     7141 atgccgaaat tcattcactt aacttttccc catggatata acgttgatcg ttcaattaca
     7201 aaagagcagc agttacaatt tcatttcgtg aagaaagaag tttatgaact aggaaaagta
     7261 gagggaactt cctttcaagg aaatcctatt actatgtatg ataaagagcg tacactttgt
     7321 gatatttgga atccgagata tgaaattgaa tatgaaatga aattagaagc attaaaagag
     7381 tacatggaag acccattgag agatccaagt aaattaagag attacatgac aaaactacat
     7441 gtagaaaaag aaatgaaata ccacatgcaa agcttatatt gatggaggaa aaagatgaca
     7501 ccgacacaat ttgcagcaaa aacaagaaat ttagcaaaga ggacaggatt aaatgcacag
     7561 ttagtacaac ggcattttat gatggatcgt ttaattgaac aaatttctga atctaagtat
     7621 aaaaatgatt tcattttgaa aggtggcttt ttattaggat caaaatatgg aatcgataga
     7681 aggacgacaa ttgatatcga cacgacattt agaaatagca aattaactga agaaaaattg
     7741 aagagtattt ttaatgattt aactaggaaa cccacgaaag aaggtattgt tttctctatt
     7801 caaggaatga aggaaacaag agaagccgat ttttatcctg gatttcaaat taaattggtg
     7861 gctaatttag agaaagtacg tgtgccattt aaaatggacg tgacaacagg agattctatt
     7921 tatcctgaag tagatacaca ctatcaccaa ttaatgtttg aagataaaaa ggtggagatt
     7981 ccagcttatc caacagcaca aattattgca gaaaagctaa gtgctacgtt cagctttggc
     8041 acagataatt cgagagcaaa agattactac gacttattta ccattccgaa actagaaaat
     8101 atcgatacga aagagttata caaaagtgtt cgaaatacat ttacaaaacg tggggataca
     8161 aaaccgttgt ccttttatta tgaaagagaa atggataaga tcataggaaa tgactatttg
     8221 gaaaagcagt gggaaaaata tcgctcagtt aacacgtttg cgaattccat ttcatttaca
     8281 gatacagtca acgaaattga tcacctaatg aaaagtgtga tcaaaattga aaatcaagaa
     8341 agaaaacggc agtttaaaag atcacaacaa atgaatcaag aaatggagag ataaagatga
     8401 tcaataatgt aactttagta ggacgcttaa ccaaagatcc agatttacgt tataccgcga
     8461 gtggtactgc agtagcgact tttaccctag ctgtcaaccg aaatttcacg aatcaaaacg
     8521 gcaatcgaga agctgatttt attaactgtg tgatttggcg caaaccagca gaaacaatgg
     8581 tgacattagc taaaaaaggt agcttgattg gtgtagttgg gcggattcaa acgcggactt
     8641 atgacaacca gcaaggacaa cgtgtgtatg tgacagaagt tgtggccgat aatttccaac
     8701 tattagaaag caaagcagcg acagaaagcc gtgcgcacgc tgatcaatcg tccaccagtc
     8761 caagcaccac cacttttgaa caacgggata cagcgacgcc taataacaat ggattgaacg
     8821 ctttacagaa tccatttggg aatccatttg gtggacaatc aatcgatatt agcgatgatg
     8881 atctaccgtt ctaagtagca ttttctattg gttgcatttg ctacggttta tgttataatt
     8941 tagtcaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg ggctagtggt
     9001 tttcttttac gtttctatta taagaattaa cgggtaggct tactgtcttt cttggcaaat
     9061 ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat tgcaaaaaca
     9121 aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag gccggggtag
     9181 cagacagcaa gactattata gcataattga aatatccaaa tgattggatt tttgctataa
     9241 ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat
     9301 aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat cgattaattg
     9361 tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg gaaaatacaa
     9421 tattgccgtc acaggtcact tcaataaacg aaatcagcta gttattgcta gcatgtatgt
     9481 tagaaatccc gatcatttta cgcgatcgat gggcatataa aaaaagaaga gttgcaatcc
     9541 taatgtagga ctgcagctct ttttgtttta catagaaaca agaaaaatga aaaggccttt
     9601 ttaggaaggc gcgagcgcct tctcaattga aaaacctctc tcactccaac cgccaccgcc
     9661 gttcgagaag aaaggaagtg aacgttgcac gttcactaag ataaagggtc ttgcaaagca
     9721 agacaaaata gaaaaaactt cctctcacca aaaggttcgt tcctgttcgt tatctcttta
     9781 ttgatttgcc agaccggcaa caagttgcct tttatcacca aaaagcgaca aggacaaggg
     9841 taaatggcac gctgcgcgcc cttgtccttg tcgcttttcg ttgattcatt ctggccaaca
     9901 aatcaataaa gaaagaacta acgaaaggaa gtaaaacctt tcctaagagg aggcagaatc
     9961 aatcatgcga aagaaatttg attattgggg tgttcccttc agcgaattat tcccaaacta
    10021 tcatgcacca catactgtcg aatgcgattg tggacaaaga gcgaaatgta tcaaaagcta
    10081 tcgtttgtat caatgtccaa catgcggaaa aaaatacacc ttgtcttatg gcgattatat
    10141 tttgattgat gagaaaggaa agaaacgctg atgaaaacat aacataaatt attgactgta
    10201 aaagaagtcg ttcaaatttt ggtggacaaa gaagtcattt ctgaaaaagt agcagaagct
    10261 ttacttattc cgcggtactg gacgatagaa acccctttag tagaggatgc accgactatg
    10321 ctatttgaag acctagtgaa gattgcagga tatgaactgc attatcaaga aaacatggaa
    10381 acttatgaaa acgaatattg gttaaccaaa ttagagaact aaaaaggaga aaaaaatatg
    10441 gctcaaaatt actatgacga atttgtcaaa ttacctttgg ataaaatggc acaaaaaatg
    10501 gaggatatga cattcctata ccatgagaca cgtgttccaa aaaaacatta taaggaaaga
    10561 ttgtcggtag ctgtggaaga aatgattgaa tcaggtgtcg aaatgaatct cattgcgacg
    10621 tactatcgaa cactggaaga actgaaaaaa caaaatgcaa aatggttttt ccaagcctta
    10681 ctatgcttgg aagtaggtgt caaaccaagc actattaaac cttctgaata tcaagcttta
    10741 gaactaacgt atgggaaatt tgtcgaaacg aaaaaagcca agactgtttc aagtgaatgg
    10801 ttagattatt ttgaaaatat caataagtat ggcgcctatt acaccatgaa aaaggaggac
    10861 aacgaaaatg aataaggtga tttatcaact aacaacggaa gatgtgtcac actttttaac
    10921 aaacaaagaa catttgaatg aagtaatcag acggattcaa aaagacttta gttgtatgga
    10981 agaaatgaag tactttattc aaagagtcga agaacaattg tatttggaaa gtgaaacgag
    11041 tcaaacgaag gtcacagtca gcaataatta tttagacgtg tataaacatc gtcctgaaac
    11101 ggtaaaaaaa ggaacggagc ttctacgact agaaacagaa aaatacatca tgaatgttta
    11161 cctagaaagg agtgaactgg tcgaaaactt tgtcagctgc acgatttgca ggaaacacta
    11221 ttactcagaa tcagaatatt attcaatttt tgagagcatg gaattaatgg aagaagaaat
    11281 ggaagagcta aacagcaaaa atgcgacgat agacgattat tatcttgtat ttactagatt
    11341 tttgacgtgt ggaacggaat ctatcgtgtt aatgggaatg gattatgaac tcgctgtacc
    11401 cgaagcattt ttgagggaat atgtagaaga agtagataac ccaggcgacg actggtacac
    11461 gactttaact gattttttag atacctacac ttacgacgat acagaagaaa tccaaaatga
    11521 acttgaccgt aaacgaatgc catatcaacg atttgaaagg aaaaaaaggc aataatcatt
    11581 tataccgaaa agtgagaatg tgtgaaataa gaacaaaaac cttgaaatta agggaatggt
    11641 tcttatttcg caccaatcgc tccaaccgcc cccgccgctt aggtggtgcg aaataagcgg
    11701 gcaaagcccg ataacctaag agaaagaagg agatccatat gaataaaatc attcctctgt
    11761 tgttcgtact gtgtattggc gagatactta tgcgtcatgg tgcagctgta catttaaact
    11821 tcgtagtatt cttaggaata ctagtatttt gtttgatttt ttggcgcttt gtgttagccc
    11881 ttgtgagtct actattcaag ttgattgcag ccatattttt catagggtta tttcgatgaa
    11941 aggagagagt actaatgcca attgcaatag gaaataaacg gttacccgtg acattagatg
    12001 aaaagagaca aaaagaattg cagcaactaa agcagaagta cggaaaaagt gaatctaaga
    12061 ttatgtgtat tgcgttagat ctattgatcg cgcaagaaaa agcaggattt gatataccag
    12121 cactaaaaaa gtgacgtcac ttttcatttg aagaaacaaa agtgatagca cttaattgtt
    12181 cctactattt agaatatttt ctatgtcctt tttattccat tttgtatcaa taactatgaa
    12241 atctttaaag tatccagatc aatttttttc ttacctgatt ctaaagattt tgttttctta
    12301 aacatattat gatttccttt cgactatttt catataaatg ttaacatagt ttatggattc
    12361 atggaatgtt aatctaattt aatagaaaag gataattaag tatatacgtt ttttcttatg
    12421 tatgttatac tatgtatata cagaaagagg tgtctactat ggaaatgtta cctataaaaa
    12481 aatggggaaa tagtaatggc cttagattgc caaagtatat tatggaatat cttggaattc
    12541 atacagaaga caaagtgaag ataatacaag aagaagtaaa cggtcagaag cggctaatta
    12601 tcgaagcggc taatatagaa aatgaattaa caattgaaca gttatttgaa aattacactg
    12661 atgaaagaaa tcatgtgacg attcaaaatt taggtgaagc agtaggtaat gaaaaatggt
    12721 gagaaaacct agacaaggcg atattctatt attgaataca gcacctcgat ctggacacga
    12781 acagacaggt aaaagacctt atattgtttt aagtcatgat attattgcgg attatagtaa
    12841 cgttgttaca gttgctccaa tttctagtac aactagaaac tatccgctat atgtaaatat
    12901 aaactcagaa tatgaaatga agacaacagg aaaagtatta ttagatcaac taacgacaat
    12961 tgattatgaa gccagagagt gtattttttt ggaaaaagcg catgatagtt tagttgagga
    13021 gttattgatg aaagttagaa cagtttttca aaaagtaagc aaataaaata gaaacagcag
    13081 catgatcaac tattcgtgat tgaccatgct gtcttttttt attctatata cggtttgtct
    13141 cgtaacattg tagtcttttg caatcttagc gatcgcaaca ccttttttta gatcctcaac
    13201 gatgttttta taaacaagac gacgttgggg atcttttgca ttggcactgt atagcttagg
    13261 acgtccttta taaacaccgt tcgcttttgc aatcttaatg ccttgtgcct gacgtcgttt
    13321 agattcggta cgttcttgtt cagcgatcat ggccaaaatt tgaatgatca aatctttaat
    13381 gaatttatcc aggagaggat tgccaattgc ttcggccatg atcggtagac ttgtgatgat
    13441 cagctgcaca tttttcttct tcaagtaatt gactgaagcg atgatctcgt cgtaatttct
    13501 tccaagtcga tcaatagctt ccacaataaa aatatcttga tctcggacga aatccagtgc
    13561 ttcttgaaaa acaggtcgat gagtaatcgt tgcgccagat tgtttctcaa tgaaaattct
    13621 ctctgcaccg aattttttca tttcttcaat ctgccgttgt tcattttgat cgatggatga
    13681 gacacgtatg tatgcaactc tcaaaatttt tacctacttt ctgcaactat ttaaaaaaca
    13741 ccctaatcat acacgagaaa accagatttt tcaatgtcgc ggtcgtgtct agttagggta
    13801 taccttatat agacaaaaac taatgatgga ggaaatagta tgtgtcactt ttctttttaa
    13861 atggcaatat tttttgtaaa taaatgtcaa tcaagaaaat ttaaacgatt atgacattaa
    13921 aaatatattt tatgaatttt ctagtatata acttgattta tctgttaaga tttattgaga
    13981 aaacgttttc ttatttttga tttcgaggtg atagacaatg aaaaataagt ttattttatc
    14041 tttaggtatt ttaactattg gaattagtgt aactggaact acaattccta catttgctga
    14101 tagtacaaat gaaccaacta ctgtagtaga taataaccaa gaattaactc ctttagatag
    14161 gaacggaata gccattggta acccaactaa cgacttaact gttactgaaa attatttaat
    14221 agtttctcca ttacttgctc gagcagcttc taaaacgata cgagtgacag gaacgatgat
    14281 ttttgataaa gttggttggc cttctagacc tcctcaatca cggaattgga aagaaaaaag
    14341 aaatggttat tggtactatg gaaaattgta tttacaaagt tataaatcag ctggaaacaa
    14401 ttggattgcg acttattcag gaaccttaac tagaaagtag ggatttttta tgccagaatt
    14461 tgtgaacaca ccaaattttt atcaagatag cgatattcta agtaaaatta atttaccgaa
    14521 agaagaatca gctttacaag ttcagcgaac tttacaggag acacaaaaaa ttcaaaaatc
    14581 aatttctaat ctagaagatt ctgaagaaaa aagaaaaaaa agagaccaaa aaacatatca
    14641 aaaagaaaaa taatgatttt aaaaaaagag tgtctagtcg acattctttt tttctaattg
    14701 aaagtgttca taaaatcacc catttctgga cactttcttt ttttgcttta tttttcaaaa
    14761 aaacaattca tttcatgttc ataaacccat aacaatatct atgttcagtt aaactatatg
    14821 gataaagtta tgttacaata aaattaatga aggagtgatt tttttgaaaa taggatacgc
    14881 ccgggtatct actggtttac aaaatttgga tttacaagaa gacagcctaa ataaatttgg
    14941 ttgtgaaaaa atttttactg atcatatgag tggggcaaaa agtaatcgac caggattaga
    15001 aatggccatt gattttgttc gctctggcga tacacttgtc gtttggcgct tagatcgttt
    15061 aggtagaaat atggaagatt tgatttcaat cgtcaatcga ctgaatgagc gtggtgtgag
    15121 ttttcatagt attcaagaaa atattacgat ggacaaatca agttctacag gacagctcat
    15181 gtttcatttg tttgcggcat ttgcagaatt tgagcgtaat ttgatcctgg aacgatccgc
    15241 agcaggacga gcagctgctc gtgcaagagg acggtttggt ggtcgtcctg aaaaattgtc
    15301 tgaacaagat ttggaattac tgaagacttt agtggatagc ggtacaccta ttaagactat
    15361 tgcggaacgg tggaacgtct caagaaccac catttatcgt tatttggcaa aaatggagga
    15421 gaaaaatgga aagacaaatt ctcattagtt tttgtcattt aatgctgaaa atttttgcca
    15481 tttatctaga aaagtgacaa tagtatgaga attttttgta agtgtctact gataacttat
    15541 tctcaaatgt tgtaaggatt ttattcattt gttaatatta aagaacggaa ctccaaaaaa
    15601 gtccgtactc taatttgcag tctctcactc ttttagagtg agagttttta ttagattttc
    15661 aaattaatta gtaaa
//
LOCUS       DACCVH010000062        15399 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.062, whole genome shotgun sequence.
ACCESSION   DACCVH010000062 DACCVH010000000
VERSION     DACCVH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.062"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            476..718
                     /locus_tag="IVV98_002051"
     CDS             476..718
                     /locus_tag="IVV98_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAP7807685.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            715..1185
                     /locus_tag="IVV98_002052"
     CDS             715..1185
                     /locus_tag="IVV98_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7807686.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1313..2527
                     /locus_tag="IVV98_002053"
     CDS             1313..2527
                     /locus_tag="IVV98_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7807687.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(3237..3425)
                     /locus_tag="IVV98_002054"
     CDS             complement(3237..3425)
                     /locus_tag="IVV98_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807688.1"
                     /translation="MAVREYHYLTVQVMAIKEDKSFTRTQIGFRSLLQGKGRGVFVST
                     ASCLSNVLNSFIQLSKND"
     gene            3516..3725
                     /locus_tag="IVV98_002055"
     CDS             3516..3725
                     /locus_tag="IVV98_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HAP7807689.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3837..5450
                     /locus_tag="IVV98_002056"
     CDS             3837..5450
                     /locus_tag="IVV98_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAP7807690.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5485..6696
                     /locus_tag="IVV98_002057"
                     /pseudo
     CDS             5485..6696
                     /locus_tag="IVV98_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6719..7645
                     /gene="glsA"
                     /locus_tag="IVV98_002058"
     CDS             6719..7645
                     /gene="glsA"
                     /locus_tag="IVV98_002058"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP7807691.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7853..9313
                     /locus_tag="IVV98_002059"
     CDS             7853..9313
                     /locus_tag="IVV98_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807692.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9534..11297
                     /locus_tag="IVV98_002060"
     CDS             9534..11297
                     /locus_tag="IVV98_002060"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP7807693.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11381..11839
                     /locus_tag="IVV98_002061"
     CDS             11381..11839
                     /locus_tag="IVV98_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP7807694.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11948..12631
                     /locus_tag="IVV98_002062"
     CDS             11948..12631
                     /locus_tag="IVV98_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP7807695.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12778..13392
                     /locus_tag="IVV98_002063"
     CDS             12778..13392
                     /locus_tag="IVV98_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP7807696.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13408..13614
                     /locus_tag="IVV98_002064"
     CDS             13408..13614
                     /locus_tag="IVV98_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807697.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            14155..15285
                     /locus_tag="IVV98_002065"
     CDS             14155..15285
                     /locus_tag="IVV98_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP7807698.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
BASE COUNT         5263 a         2447 c         3213 g         4476 t
ORIGIN      
        1 tttttccgcc atgcttgcaa gggggcggtt cgcttcggcg gttcggcgag cttgcgagcc
       61 gttcaaagcc cccgttatct aacaaggggg gcacaaaaaa caagaaacac tatacactaa
      121 caagcggaaa acgctgtatt tataaggcaa aaccccattt ttacagtagt gatataaatt
      181 gtacctatat cactatgaaa attgaatagt aaatatgaga aagacagttg atttcaaaaa
      241 ataagaaatt gattgtcgtt ttcttttgca gaaatttaag tgcaggcaat tatggtagtt
      301 gtcgtaattg ctgtcagctc agtgtttatc actgatggtg tgaaagattt acggttggag
      361 atgttcaata agattattgg tgcttaatta tttttattgt agtgctgata tgagaatgtt
      421 ataattgggg tataaaacat acaaataaat ttgctgaaaa atgaggtatc aaaatatgga
      481 aaatgaatta ctggaaaact taggaagact tcacacaact gaacttggcg ttattagaat
      541 taaaaagaac ttatctttga atgtagaaaa tgtaattgaa tggtgcaaag aaaaaattag
      601 cctttctaat gcggaaatca caagaaaagg aaaaaactgg tatataacga ttgataattg
      661 tattataacg gtaaatgcgt acagttatac cgttatcact gctcacaagg taaaatgata
      721 aatttttcta taaaggaatt aaacgcattt gcagttattg ggcaggaagt agaactgact
      781 aattatcaaa aaaagaatat tcagattagt acacagtttt ggagaaagtt taacagtagt
      841 ttgaaaaaag cgtatctttc acaatcagga aattgggtaa aatatgcttt tatggaaaga
      901 agaaatggaa aactttatta tttctgttct attccccaaa gaaccattac cccagagggc
      961 tttctgtata aagaaatacc gtcttataaa tatttggttg tggagcatat tggtgctatg
     1021 gataaaatat atgaaactta tggcaagatt tatgaagaaa ttattcctag tacatcgtat
     1081 attcctataa aagatattat cctacacttt gaaaaatacg attatcgttt tcattggaat
     1141 agtgataatt cagttattga aatttggata cctattcaag attagaagca attttatatc
     1201 catacacaca aagcagttag tcttaggatt gactgctttt tctatacaga tttttaatga
     1261 caggcaatta tcaattatgg tagttgcctt ttttgattgg aggaattgaa gaatgaatga
     1321 taaaaacttt attgaagaac taagacaaaa gcgtgaggaa tacggagtaa cacaaacaag
     1381 gcttgctgtt gcctgtggta tcagccgtga atattacaac cgcattgaaa aaggaaaaca
     1441 gccattgaat gacgaattaa gagaaatcat agaaaaacag attgagcgtt tcaatccgca
     1501 agaaccacta ttcttattga ttgattactt tcgtgtccgc tttcctacta cggacgcatt
     1561 ggcgattatc cgtgatgtat tacaactgaa atctaattac atgctttatg aagattatgg
     1621 aaaatacgga tatgaaagca aatatgtact tggcgacatc aatatcatgt gttccatgca
     1681 ggagcattta ggtgttttat tggaactgaa aggcaaaggc tgtcggcaaa tggaatgtta
     1741 tctgctggca caggaacgct catggtatga cttcatgctg gattgtatga cggctggtgg
     1801 tgtgatgaaa cggcttgatt tggctatcaa tgataaagca ggaatattgg atattccaaa
     1861 gttaaaggaa aaatacaagg ctggcgaatg tatgtcctac ttccgtatgc agaaagatta
     1921 cagcggtaca gaaaaatgcg gtagcgattt accaaagaat acaggagaaa ccttatatct
     1981 cggttcaaca agtagcgaat tatatatgtg tgcttatcag aaaaattatg agcagtatgt
     2041 caagaatggc acagaaattg aagatacgga gattaagaac cgttttgaaa tacgcatgaa
     2101 gaacgaacga gcctattatg cggttgtaga tttactgacc tatcgggacg ctgaacgcac
     2161 cgctttttct atcatcaatc attatgtccg ctttgttgac agagaggacg acaagccaaa
     2221 aagtcaatgg ataacaaatg atgattgggc atggtttgta ggggaaaaca gagagccgat
     2281 acgcttaacc acaaagccag agccttacac tttacaaaaa gcgttgcatt ggctacaaag
     2341 acaagtcgca ccaaccataa aaatggtaca ggcattagac agagaaaatc gtacaacgat
     2401 actgaaagat atgattgagc aggcagaact aaaagacaag cataaacatt tattacaatt
     2461 agagaaatca accatagaag aacgtataga taccgctgtt ccacaagaga atgacggtat
     2521 tttttaatgt aattgaaaaa tttcagattt agtcagcaaa gagctgtttt cattccctat
     2581 gtgaagtgaa agaagaaaaa taaatttttt attaaatctg caacaaaatg gctacttgcg
     2641 tacagatatg gtgcgagaaa aggaaatcta aacttttttt gaaaataggt cattaaatcg
     2701 gggcttgctg tccctatatg aagtgaaaga agaaaaaagt tttgaaaaaa tgacggaaat
     2761 tcgtgattag tggacagtct tctgtgaaaa gaggaaaaac atcatcattt tgtattcaaa
     2821 caggcattag cagttgagtg ttgatgtgaa aagatgaaaa tactttgttc tcaacttaac
     2881 aatttaaggt ttccgttccc tatatggtgc aaagaaaata tttcattcta ttgttggcag
     2941 taacggtatg gtttgggtag ttagggtgtg aaaaggaaaa tattcttttt tcatcatcaa
     3001 cttagcaaaa tgacattttc tatccctata tggtgcatga aaagaagtta aaatttttcc
     3061 atttaaactt agcaaatgga cgtttgctgt acagatagta gtgaaaaagg agaaaatcaa
     3121 ccgttgattg ccaaaatgaa ccgttccatt tgtactaata atggaaaaag ttttggattt
     3181 tggttacgtt tctcctcttt tccaacgcga tatataggaa agacgatttt tttctttcaa
     3241 tcgttctttg acaactgaat aaagctattc aatacgtttg acagacagct agccgttgaa
     3301 acaaatacgc cacgaccttt cccctgcaag agcgagcgaa aacctatttg tgttcttgta
     3361 aaagatttgt cctcttttat cgccatgacc tgtactgtca gataatgata ctcccgtaca
     3421 gccacagctt gagcattaag agcgtcgcac gcaatgggta cggctacata agaactatgc
     3481 agaggtggaa ctcctgtggg ctatgacaaa agccgttgaa ttgcttagaa agattttaca
     3541 gaaagggggt atgtgttatt gataatgctg taaaaacaat tcaaaagaaa aatggcaagt
     3601 gtggcattgg caacagagga aagacaaaga ttgtagtaaa agagcatttt tccgaaaagg
     3661 gcaaaacaat ggaagaactt ctaactgatg tcatgctgga aaaagcaaag cagacaatcg
     3721 cataaaatcg gtgcagttgt aagaaataga ttgaatgaca aaaagtaccc gtgttatact
     3781 ttacttgcaa gcaggtattg taaacacggg ttagttataa aggaggataa ctgacaatga
     3841 aacaacagat ttacaatact gcactttatc ttaggttaag ccgagatgat gaattacagg
     3901 gcgaaagttc cagcattacc acacagagaa gtatgttgcg tttatatgca aaagaacatc
     3961 atttgaatgt cattgatgaa tatattgatg acggctggtc gggaacaaat tttgacagac
     4021 cgagttttca aagaatgatt gaggatatag aggcaggaaa aatcaactgt gttgtaacga
     4081 aagacctttc ccgtcttggc agaaattata ttatgacagg acaatataca gaattgtatt
     4141 tccctagtca taatgtccgc tacatagcga ttgatgacgg tgtagacagc gaaaaaggcg
     4201 aaagtgagat tgcaccattt aagaacatca tcaatgaatg ggtggcaaga gatacaagcc
     4261 gtaaagtcaa atcagcattt aagacaaagt ttgcggaggg ggctcattac ggtgcttatg
     4321 ctccgttagg atataagaaa caccctgaca tcaaaggaaa actgttggtt gatgatgaaa
     4381 caaaatggat tattgaaaaa atcttttccc tagcctatca aggttacgga agtgcaaaaa
     4441 tcacaaagca gttaagagca gaaaaagttc cgacagcgtc atggctaaat tttacaagat
     4501 acggtacttt tgcacatatc tttgagggaa aacccgaaag taagcgttat gagtggacga
     4561 ttgctcatgt caaggcgata ttgaaaagtg aggtttatat cggaaacagt gttcacaata
     4621 tgcagtctac ggtatcgttc aagagcaaaa agaaagtgcg taagcccgaa agtgaatggt
     4681 ttcgagtaga aaacactcac gagccgatta ttgacaagga agtgttctat cgtgtgcagg
     4741 agcagataaa atcaagacgc agacagacaa aggaaaaggc aacgccgatt tttgcagggc
     4801 ttgtcaagtg tgcggattgt ggttggtcta tgagatttgg aacgaataag acaaataaaa
     4861 cgccttacag ttattatgct tgcagttact acgggcagtt tggcaaaggt aattgttcta
     4921 tgcactacat tcgttatgat gtgctgtatc aagccgtatt ggaacgcttg cagtattggg
     4981 ctaaggcagt acagcaggac gaagaaaagg tattgaacaa gatacagaaa gctggcaatg
     5041 cagagagaat acgggaaaag aagaaaaagg caagtacatt gaagaaagcc gagaacagac
     5101 aaaatgagat tgaccgttta tttgcgaaaa tgtatgaaga tagagcctgt gagaagataa
     5161 cagagcgaaa ttttgtgatg ttgtccagca agtaccaaaa agaacagata gaactggaac
     5221 agcagataac aagcctaaga gaagaactaa gtaaaatgga acaggatatg ataggtgctg
     5281 aaaagtggat tgagttaatc aaggaatatt ccgtaccaaa ggaactgaca gcaccattat
     5341 taaatgccat gatagaaaaa atcctcatac atgaagcaac aacgaatgag gataacgaaa
     5401 gaatacagga aattgagata tattaccgat ttattggaag agttgagtaa tcaacaagag
     5461 taatattttt aactaaggga aaccggcggt gtctatactt gggtcagtcg cacattggga
     5521 aaacgattcg gttttgccgc aatctttttc caatggtttg agataacagt tggctacttg
     5581 accatgctgt atttcttaac tggtgcatta tcctatgcaa cgggtattgg tgctatacaa
     5641 aacaataaat atctgaaatt ggcaatccta ttgattattt tctgggctat tttactctca
     5701 cagttaaaag gaaccaaata cacttcattg attgctcgga tcggttttgt agctggtatc
     5761 ttgttgccag cattagtctt gtttggctta gggatccatt atgtcgcttc aggcgctcca
     5821 ctacaaacga tactgtctat gaaaacattg attcctgatt tttcgaaatt gcctacgctg
     5881 gttgtttttg tttcctttat tttagcatat atgggcgtag aaacatctgc cagtcatgca
     5941 aatgaaatgg aaaaccctaa aaaggattat ccattagcaa tgtttgtatt ggttattctg
     6001 gcaatcattt tagatacttt tggcggattg accgtcgcta ctacagtacc tcaacatggt
     6061 ttgtctctta atacaggggt gattcaatcg ttagaattcc tattaagaca cattgatcca
     6121 aatcttgcat ggattgcgaa aattcttgcg attcttgttt gtttaggtgt catcggagaa
     6181 attgcttctt gggtaacctc tccttcaaaa gcacttcacg tagcagcaga agaaggatta
     6241 cttcctgaat attttgcaaa agaaaacaca cacggtgttc ctgctcattt gatgatcgca
     6301 aatgggatcg ttgcaacaat ctgggcagcc gtctttacat taagcggcgg ggggaataat
     6361 ctttcatttc ttgcagcgat gtcattgact gttgtaatct acctgatgtt gtactttatg
     6421 tttttcgcgg gctatttgaa gctggttttt aaagatgaca gtcttgaaag agcctatcag
     6481 gttccaggcg gaaaagttgt aaaagtaatc gttgcttgtt taggtctttt gacttcactt
     6541 tttgcttttt gtatctcatt tgttccacct gctagtatcg cagctggaca gcatgggatt
     6601 tatgaaacga ttctgattgt ttcttatctt atcgtcttag ttattccatt tacgatctac
     6661 gcatgccgtc ataaattcca gcatgcagaa aaataaaaaa tgaaagctgg ttattcaaat
     6721 ggaagtaaaa gaattagaac aattgattgg aaaaaatttc cactattatc aaacaggaca
     6781 agtggcggat tacattccag cattagctga agtggatccc aaacaattag gtatggcgat
     6841 ttatgatttg gatacaaaac aactgattga gggaggagac gccgatgtgc gctttgccat
     6901 cgaaagcatg tcaaaagttc ccgtattgtt attagcaatc aaagacaacg gaatagaaaa
     6961 agtctttcaa acaatcaaca cggaaccaac cggttttgcc ttcaattcta tcatgaatat
     7021 ggaaatcaat catcgcaaac atccaatgaa tccttttgtt aatgcaggag cgattgcaac
     7081 aacctcgttg attgccggta aagatgcaga tgaaaaattt gagcgaatct tgtcatttat
     7141 gaaagagatc tgtgatgatc ctaatatcac attgaatgaa gaaatctatc attctgaatc
     7201 aagaacaggt gatatcaatc gctctcttgc ttactatatg aaaggtaatc aaatgatcga
     7261 aggagacgta ccggagatac tcgatgctta tttcagacaa tgctccctca atgtcaccgc
     7321 tacaggcata gcaaaattag ctgctgtgct ggcaaataaa ggaattgctc cttggaatgg
     7381 caaacaaatc attactgaag aaagtgctac aatcgtcaaa tcaattatga caactgctgg
     7441 tttgtatgat gaatcaggag agttttccgt ccatgttggt gtacctgcaa aaagcggtgt
     7501 aggcggcggg ttgatggcag ctgtgccaaa tcgttacggc ataggtgtct tcagcccggc
     7561 actagatcca tttggtaaca gcgcagctgg tatccaattg ttgaaagatg tagtcaaaga
     7621 actagacgct gacatctttg aataaccatt cttgaaagag gctggggtaa aagtccaaac
     7681 ggctcaaagc tacctacaat gaggctgaaa ttgtgagctt gtttgacttt tgtcccagtt
     7741 tcttttttta ttggtttttg aaagggcttt tctaaataaa aaggaaacaa aaatacgatt
     7801 tacagatatg attaaataaa atcataagaa aaactggagg cgtgtatcag gaatgctgga
     7861 aaattacatc gagcgaaata tatttagaaa agtgtatctg tgtgaacaat tatttgaatt
     7921 ccaagaaata gacatcgaac aaacagctat ttctctaagg gtgactacac caacgatcct
     7981 tcacgatcta gaaagtctag ccgagtgtct agaatattgt ataaaagaac aagtaagaga
     8041 gaagcataag tataaactcg tattcaaaca tggtattgct ctttctgagc tcacacagtt
     8101 tctgtacggt caatcttatt ttttaaagtt tttaagttat tattttaatg gtatattcac
     8161 gagtacagaa ctggctgatc ttgaatttat ttctttgagt aaagtatata caatcaaaaa
     8221 aatcgtattg gattttttta aagaaaatga ttatttgaaa aataaagaaa tcattatccc
     8281 agaatttgac tcgcggaaca tcttgctagc tttagtacgt tatgtcaatt gggaaggcta
     8341 tgaaaataaa aatccgtatg tagaagaagc ttgtaacgag ttgattgatt atgtagagac
     8401 tcattttttt aaaagaagat attcggaaga tgaaaagtcc tttatcatac gagaaataga
     8461 gatcgcaatc ggaagaaagg catttcccct tggactgaaa gaagaagata agaaaagcgc
     8521 agaaacgaag ccgttatttc aattagtctg tcaaggattg gaagagcaaa aaggaattct
     8581 agacttacaa gaagaagatg tctattatat tttttctttg ttcaacagta gaaattatac
     8641 caatgagaac atggagctgt taagaaaaga tttcgaagtt gtttataaaa attttgttct
     8701 caatgaccta tcactgaatg aattgatttt acagattatt agtatcgctg aaatcgacga
     8761 tgcagaaaat tttattttca agcaatcctt tttacaattt gtccgtacgt tgtgggcaga
     8821 tggacaagta tttttaccgg aaaggatcta tcttctatca gaaaaagaac aacttctgta
     8881 cggaaaaatt gtagaaatat tggaagagtg gaaaaagaaa aatcaaatcc aactaagatg
     8941 gaatgaaaat ttcattcgaa aattcgtcaa aagtctttct ttgatcaaca gtgaacaagc
     9001 ggggagacag gaaatagaaa tttttgttgt ttcagaaagt tcagtcaaac aattttttta
     9061 tcgaacccaa tttcatttgt atgcggaaga aggcatcgct gaaataaatc ctattttatt
     9121 tcgttcatta gaagaattgc ctgatgaatg tctatgtgcg aaaaaaagag tggttttgtg
     9181 cgatgctgct agctatcaaa atggattaga aactgaaaag acaaagatct atccaatctc
     9241 attaaaaggt gcaaacatcc atttgtatca tattgctcag gaacttcacc tattaaaaaa
     9301 acatatttct tgatgagacc ttaattagga gaccttctac aaagcttttt aattgtctgt
     9361 agaaggtttt tatttgagtc ctgattcgtg cgaagatcta cttatataac aagctttctc
     9421 tgaaattttt ttaaaatgct attgacttag agtcaactct aagtagtaga atagataaag
     9481 tgtaacaaat ctattttcat taaaagaaga tagtacggag gagagaatgt attatgagta
     9541 cagtattaca tgtattggat gcaatcaata gccccgcaga tgtcaaaaaa ttatctgttg
     9601 aggaaatgaa acagttggca gaagagatgc gccaaaaaat cttgcaaaag gacagcgatg
     9661 taggtgggca cgttggtccg aatctaggtg tagtagaatt aacgattgcg tttcattatg
     9721 tatttgattc accaaaggat aaaatcgttt gggatgtttc ccatcagtct tatggtcata
     9781 agcttttaac tggtcgaaaa aatggttttg aaaaaggaca ttaccgtgaa gtgagcggat
     9841 attccaacca acatgaaagt aaacatgact attttacagt ggggcacaca tctacatcta
     9901 tcagcttagc aacaggttta gctaaagcga gagatctgaa gaaagaatca ggaaatgtgg
     9961 tagcatttat cggtgacggc tccctaagtg gtggcttagc ttttgaagga ttgaacaatg
    10021 gtggtgtttt acaatccaat ctaatcgtat tagtaaacga taatgagatg tctattgatg
    10081 agaatcatgg cagtttatat aaaaacttag ctgagcttcg tcaaaccaac ggtaaaagca
    10141 gcaataacct atttaaagca atgggatttg attatcgtta cgtggataat ggaaacgatc
    10201 tggaaacggt gatccgttta tttgaagaag taaaagatat tgatcatccg attgtacttc
    10261 acgtccatac ggaaaaaggt cgcggttatc agccggcaat cgataataaa atgaaatatc
    10321 attggcatgt accatttgat ctgtccaccg gggaggcaaa gcaagtaact tctggagaaa
    10381 catttaatat gatcatcatg gattatttgg ataagaaaat gcaaacaagt acagctccta
    10441 ttgccgcagt caatgcagcg ataccaggcg cctttggact gaaaacattc caagaaaaac
    10501 atccagatca ttattttgac gtggggatcg ctgaacagca ctctatcact ttcgcttctg
    10561 ctttggcttc tcagggagta cgtccagtcg tcttccaatc aagtactttc ttgcaacggg
    10621 catatgatca attatcacat gatttagcga tcaacgagaa tccagtgatt attttagtcg
    10681 gtggcggaac gatctcagct agtgaccgaa cacaccaagg aacatttgac attccttact
    10741 tatcaagtat cccgaacatc aaatatcttg ctccagcaac aaaagaggat atgatctcta
    10801 tgctagattg ggcgttcgaa caaacagcgc agcctgtagc aatccgaatt cctacacatg
    10861 gtgtagaaca tggtacagct atcgcaaatg attatagtat tccagcctat caaacagtaa
    10921 ataatggagg aaaagtagca attttagctt taggcggttt tcttgaatta ggaaaagaaa
    10981 cagtaaaagc ttttagaaaa aaaggaatcg aagcaacgtt gatcaatcca ggaacgatca
    11041 cagaaaatga cgtagaaaca ttagataaat taaaagaaac acacgaatta gtcatcacat
    11101 tagaagatgg tagtttgtca ggaggatttg gcgaaaatat cagtcgttat tatggtgatt
    11161 cttcaatgaa cgtattaaat tttggtgcag agaaagaatt cacggatagc gttcctgtag
    11221 ggcagcttta tgaacgttat catttaacac caaaacaaat cgttgaagat agtctgcgtg
    11281 tcttgaatat tcaataattc attatgctca ccatccagat aattgtttat actagtatct
    11341 ggatggtttt ttcattataa aaagcaaagg ggtggatgtt atgtatcagc aagtagaaga
    11401 atatgtcaaa aagttccaag aaaaatatcc tagttatcaa tcagaaaaat taggtttctt
    11461 ttcatttggg gatacagaaa aaatggcaga cgagttgagc gaactagttg taaaaaagat
    11521 aaagactggt acatcaagtg gttacgatct gtataaacaa gagaatgagc ctttaccaaa
    11581 agttggtcaa ttagacgtgg tcctgaatgg aaaaaatgaa ccagtttgta tcatcaaaaa
    11641 tataaatgtg accatcttgc cttttagtga agtcacgaaa gagcatgctt ggaaagaagg
    11701 agaaggggat cggacattag cttattggcg gaaagtccat gctgagtttt ttaaacatgc
    11761 ttataaagaa gcgttgaaca tagaatttac agaagagaag ctggtcgtat acgaagaatt
    11821 tgaagtaatt ttcttttagt aagaaaggtc tgctgaaaga aatagctcat tattgtctcc
    11881 tgaatagaaa agggttacat ttttatatga agctgtattt ttatataaca ttactggagg
    11941 agatattgtg gatacactgg aacaaatcaa aggcggagtc gtcgtttctt gtcaagcttt
    12001 ggaaaacgag ccgctacaca gttcttttat tatggggaga atggctttgg ctgcaaaaga
    12061 aggcggagca gttggtattc gagcaaatac gacagaagat atcaatgaaa tcaagcgaat
    12121 cgttgattta ccggtaatag ggattatcaa aagagattac gatgggtcag aagtgtttat
    12181 tactgcgaca gaaaaagaag tggaagaact tttggagacg caagcagaaa tcattgcact
    12241 ggatgcaact tctcgtaaac gtccgacaga aaaaacaact gctgaacttg tccaaatgat
    12301 tcacgaacac ggtcggttag ctatggcaga tatttcgact tttgaggaag cgcttcaagc
    12361 gcaagaagat ggttttgatc ttttgtctac gactttagca ggctatacag aatattcacg
    12421 aaagacgcag acacctgatt ttgatttatt gaatcaaatc atagaacaag tcgatatccc
    12481 agtaattatg gaaggacata ctgactctcc tgaacaagta gagaaagcat atgaattagg
    12541 tgctttttca gtcgtagttg gatctattat cacccgtccg caattgatca ctaaaagata
    12601 tgtcgaagcc gcaagtaaag caaataacta aaaaacacgc acggcacaga ttcttgacaa
    12661 aaaagaaaaa ttgatagata gtttaaagca gattctaaga agatgaaaaa agcattactt
    12721 ttcattttgt cttcaagatc tgctttttaa cgaattttat agaaagaagg cgaaaccatg
    12781 tttgaacgga gtccttcaga attgacagaa cgtgaaaatt acaagttgct gattggttca
    12841 gtcatcccta gaccagtagc agtagtaacg actaaatcag caaaagatat agtgaatatc
    12901 gcacccttca gttacttcaa tatcgtcagt tcgaatcgac ccatcttatc cttggcgatc
    12961 cagagaaaac aagatgcagt aaaagacaca gcaaagaata ttcttgagac aagagaagct
    13021 gttatccata tccttgatga ggacaacgta gaagaagtaa ataaaacagc agccaatctg
    13081 cctaatgagg aaagcgaact gtacctgact gacttgactt taactgattc agtaatcatt
    13141 tcagtaccag cattgacaga agcaaaagtt cgttttgaaa catccttata tgaacatgtc
    13201 gagatacgga ataaaaataa agtaacagct gatttatttt tgctagaagt acagaaatat
    13261 catttaaatg aaacagtcta tgatgataag acaggaagga tcgatccaag aaaattgaat
    13321 gctgtaagcc gtttggcagg aaatgattat gcagcaatag gagaaatttt cacgattgca
    13381 cgtcccgaat aaaaaggagc actagttatg ttaaaaataa gctataaacc atcgacagat
    13441 tcaaaagaaa tgaaaaaaga atatgaaaca gtgaatgatt ttctgcaagg gcagtactta
    13501 gaagttccgc cattgcaaga ccattttgtc gttactactg ttactttaga tggtaaggaa
    13561 atagaaatgc cagatcaaac gattagcgga ttgtttaatt actttaacaa ataaatattt
    13621 attccgaaaa gtgaaaaaac atataaaaaa acacataaaa ctaaaaaatt atcaaagaat
    13681 cctggtgcaa ctgaaagaat ttgcaacggg attctttcaa cttatttgtt atttttttct
    13741 aaaaaatatt aaagattgtt aaatttcact atttcatttc aaattccatt gcctaatcat
    13801 taggaaaagt ctatcatgaa ctcgtaaata gaatatagta ataaccttgt taggtgaggc
    13861 tcctatacaa acataggctg ttgcccagaa acgtcgaaag tcgccaatgg gtaaaacaga
    13921 aactgttgga ttaaggcttt ttccaatagc taagaatgtt ttctttacgt tgtatagtgc
    13981 taaaactcgg acgatgagat gatgctaggt cagaattctt gttcgaaaag gtttctgacc
    14041 ttttctttat atttttgtga ctgacttatt tgatgagaca aactcgctcc tcacctgaca
    14101 agtggattgc tgtgtgagga ggagatgcgg tgaaaaaaga tcgattggtg gattttgggt
    14161 ccttatttga ctttgtccat gatcggtctt ttagaagtat acagtgccag ttcttatcgt
    14221 ttattgcaag ccgatgaaaa tacaaaaagt ctattattgc gtcaactaat tttcatattt
    14281 ttgagttgga gcgtgatctt cttagctcgt tcagtcaaac tacactattt acttcaccct
    14341 aaaatagcag gatacggttt agccttatcg attttctttt tagtattagt aagaataggg
    14401 atattcggtg tcactgtcaa cggcgcacaa cgttggatct ctctgtttgg cattcaattc
    14461 cagccttctg aactggcaaa tctttttttg attttttatt taagctggtt ttttcgtgac
    14521 ggaaatagta gcccaaaaga tctaaaaaaa ccattcctga ttacagtagg tataactttt
    14581 ctgattttat ttcagccaaa gattgctgga gcattgatga tcctttcgat tgcgtgggtc
    14641 atattttggg cagcggcggt tccatttaaa aaagggatct atctaatcgt tactttttct
    14701 gcattgctga ttggagcagc aggcggggta ttatatttag gaaataaagg ttggcttcca
    14761 cagatgttta atcatgctta tgaaaggatc gcgactttaa gagattcttt tatcgatagt
    14821 catggtgcgg gctatcaaat gacccattcg ttttatgcac tatataatgg tggcatattt
    14881 gggcggggat taggaaatag tatcacaaaa aaagggtatc ttccagagac agaaacagat
    14941 tttatttttt cgattattac agaagagctt gggctaatcg gtgcattgtg tgtgcttttc
    15001 ttattgttct cattatgcat gagaatcttt tgtttaagca gtcgctgtaa aaatcagcaa
    15061 gctggattgt ttcttttagg attcggaact ttgctattcg ttcagacgat aatgaacgtg
    15121 ggaagtatcg cggggctgat gccaatgact ggtgtgccat tgccatttgt tagctacgga
    15181 ggaacaagtt atctgatcct ttctttagga atcggaatca cgttgaatat ttcttcaaag
    15241 atacaggccg aagagttggc gctctatcga cctgaaaaac aataaagaga aactgagaaa
    15301 ctctcagttt gaattatcat aaagtacaat cttttatttt tcaagcgaga ggttctttta
    15361 gaaagaggaa ttcgcaatga aagtatctca aaaaatcat
//
LOCUS       DACCVH010000063        15230 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.063, whole genome shotgun sequence.
ACCESSION   DACCVH010000063 DACCVH010000000
VERSION     DACCVH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.063"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            278..787
                     /locus_tag="IVV98_002066"
     CDS             278..787
                     /locus_tag="IVV98_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7807699.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="IVV98_002067"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="IVV98_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7807700.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="IVV98_002068"
     CDS             2322..3302
                     /locus_tag="IVV98_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7807701.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="IVV98_002069"
     CDS             3424..4842
                     /locus_tag="IVV98_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP7807702.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="IVV98_002070"
     CDS             4913..6382
                     /locus_tag="IVV98_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7807703.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="IVV98_002071"
     CDS             6392..6859
                     /locus_tag="IVV98_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP7807704.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="IVV98_002072"
     CDS             6895..7767
                     /locus_tag="IVV98_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7807705.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="IVV98_002073"
     CDS             7848..10382
                     /locus_tag="IVV98_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7807706.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="IVV98_002074"
     CDS             10538..11311
                     /locus_tag="IVV98_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807707.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="IVV98_002075"
     CDS             11304..12095
                     /locus_tag="IVV98_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7807708.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="IVV98_002076"
     CDS             12105..12596
                     /locus_tag="IVV98_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807709.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="IVV98_002077"
     CDS             12614..13024
                     /locus_tag="IVV98_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7807710.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="IVV98_002078"
     CDS             13028..14428
                     /locus_tag="IVV98_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP7807711.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="IVV98_002079"
     CDS             14451..14825
                     /locus_tag="IVV98_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7807712.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5288 a         2134 c         3045 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacaggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DACCVH010000064        14820 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.064, whole genome shotgun sequence.
ACCESSION   DACCVH010000064 DACCVH010000000
VERSION     DACCVH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.064"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(296..1024)
                     /locus_tag="IVV98_002080"
     CDS             complement(296..1024)
                     /locus_tag="IVV98_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7807713.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="IVV98_002081"
     CDS             complement(1002..2576)
                     /locus_tag="IVV98_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7807714.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="IVV98_002082"
     CDS             2805..3743
                     /locus_tag="IVV98_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807715.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="IVV98_002083"
     CDS             3755..4666
                     /locus_tag="IVV98_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807716.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="IVV98_002084"
     CDS             4690..6162
                     /locus_tag="IVV98_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7807717.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="IVV98_002085"
     CDS             6213..6824
                     /locus_tag="IVV98_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7807718.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="IVV98_002086"
     CDS             6854..8767
                     /locus_tag="IVV98_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAP7807719.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="IVV98_002087"
     CDS             8895..11876
                     /locus_tag="IVV98_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAP7807720.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="IVV98_002088"
     CDS             11873..13534
                     /locus_tag="IVV98_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAP7807721.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="IVV98_002089"
     CDS             13574..14506
                     /locus_tag="IVV98_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAP7807722.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4818 a         2333 c         2979 g         4690 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
//
LOCUS       DACCVH010000065        14795 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.065, whole genome shotgun sequence.
ACCESSION   DACCVH010000065 DACCVH010000000
VERSION     DACCVH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.065"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            141..398
                     /locus_tag="IVV98_002090"
     CDS             141..398
                     /locus_tag="IVV98_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807723.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1043)
                     /locus_tag="IVV98_002091"
     CDS             complement(630..1043)
                     /locus_tag="IVV98_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAP7807724.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
     gene            complement(1412..2104)
                     /locus_tag="IVV98_002092"
     CDS             complement(1412..2104)
                     /locus_tag="IVV98_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7807725.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            2189..2365
                     /locus_tag="IVV98_002093"
                     /pseudo
     CDS             2189..2365
                     /locus_tag="IVV98_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(2541..3110)
                     /locus_tag="IVV98_002094"
     CDS             complement(2541..3110)
                     /locus_tag="IVV98_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7807726.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(3184..3507)
                     /locus_tag="IVV98_002095"
     CDS             complement(3184..3507)
                     /locus_tag="IVV98_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807727.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3661..4473)
                     /locus_tag="IVV98_002096"
     CDS             complement(3661..4473)
                     /locus_tag="IVV98_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807728.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4827..5675
                     /locus_tag="IVV98_002097"
     CDS             4827..5675
                     /locus_tag="IVV98_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP7807729.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5820..6761
                     /locus_tag="IVV98_002098"
     CDS             5820..6761
                     /locus_tag="IVV98_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP7807730.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6751..8922
                     /locus_tag="IVV98_002099"
                     /pseudo
     CDS             6751..8922
                     /locus_tag="IVV98_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(9034..11205)
                     /gene="copB"
                     /locus_tag="IVV98_002100"
     CDS             complement(9034..11205)
                     /gene="copB"
                     /locus_tag="IVV98_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP7807731.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(11225..13411)
                     /locus_tag="IVV98_002101"
     CDS             complement(11225..13411)
                     /locus_tag="IVV98_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP7807732.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="IVV98_002102"
     CDS             complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="IVV98_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP7807733.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(13633..14073)
                     /locus_tag="IVV98_002103"
     CDS             complement(13633..14073)
                     /locus_tag="IVV98_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP7807734.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(14147..14686)
                     /locus_tag="IVV98_002104"
     CDS             complement(14147..14686)
                     /locus_tag="IVV98_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7807735.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         4283 a         2991 c         2564 g         4957 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaagtg aactgaaccc caaaagttga
     1321 actatttaat ggactgtttc cgatattcta ctggagatag tccattaaat agttcaactt
     1381 ttggggttca gttcaaagag ggggggattt tttatcgttg tggaatattt aaataccaac
     1441 gcttgtcatg aaaatcttgt gctccaccct tagtatttcc ttctggatcg tttgtcgcac
     1501 gcatcatgac gtatactttc ttattaggga aatcacgcat attgaaagat acatgatagc
     1561 caacatttcc taaagtatta taagcttgat ttacgtctgg tctataaatc ccatcagctc
     1621 ttactctagc tagttctttt ccagtattgt agtccataat gaaaatatac tcgtatttat
     1681 aattagcaat gtgccatcca gctacatgca agtttgcgtt ttcgatttct ccgaactgat
     1741 caatgtgggc gtaatttgtt ccatctgtca gcgtagaatt tgcagcacct gctcgagttg
     1801 gatcaattac tggtttatcc tccgaagtag ttggattatc atccgtaaaa ccatgagcca
     1861 aatcataggc tagtttttct ttacttacac ccatttcaga aagataaccg taaggatctg
     1921 tatgatcgcc ccaaatattt tgtgttaccc ataaatgcga tttgattcct ggttggttat
     1981 aaggagtgtc taatgttaat ggaataccat atttcattgc tgaatctctt gccaattcaa
     2041 cgtatacttt atagttcttt tcaaaagttt ctttatcatg tgtatgttgt aactcgattt
     2101 gcacaggact tttggctcac gaggttgtcc tactctacat cttgctgata gatatgctga
     2161 aaggaaaaca ccaacattat gttttgcttt ttcagctaga acgagacaag caggaatacc
     2221 tttagaagat atcaaaggtt ttttaggtca taaagatgtt tccactacac aagtctatgc
     2281 ccatatttct cccgaagtga aaaaaagatc aatgaatcaa ctagaaaact atatagaaga
     2341 gcaaataaaa aagcactcaa attgagtgct tttttaagct cactatcact aaaactatca
     2401 ctaattttat ttataagcga acatgtttct atcactgatt ttttaaatct agcgaaaaac
     2461 ccttatctta aaggcgttcg ttcaattctt tggcaaggtc ttcaaagcct ggcttgccta
     2521 gaagtgcgaa catggttttc ttatagctca tgtagaaaaa ttttcttgat gatgatttta
     2581 tccatcaatt gagattgact gttttgctct cctatgattt cagctatgat tgtccgattt
     2641 tgcggttttc ttcttaactg gtagttgatt ttcccagttt ccatcaactc gctaagcata
     2701 tccacgactc cgccaaatcc ggtctttttc gtaataaaac ctagtgctac cattcgttca
     2761 tctagatttt ttgctgtaat cgtcacacca gtaatgagcg agtgctgtaa tgtttgggcc
     2821 agctcttcca tcccttcagc attggatacg acggaagctg ttttgttaat aggttcttcg
     2881 tttatttctt ttggttcttt cctctccact ttcactgttt gacgaaggac atctagttct
     2941 tgcaagagcg tttcgtattg ttcttgggtc agcatcacgc cagctacttt ttcacgatta
     3001 aatatatata cgccagttcc cgcgtctcgc gcttgagcaa atacatccat cggcgatcgt
     3061 ttcacttctg tgatcgaaga tgtgggaact tctaatttct ttaattccaa tggatttcct
     3121 cctttactaa tcgcttttta ttatagcaca gactgacttg ttttgatctt ttttccaaag
     3181 gttttatcgg tttttgccta accagtaatt gatatcggta agaagtcttt cgataccaaa
     3241 tgaaggatgg tacagatacg ttttttgatc ttcgttatgg tctagtggaa aaaaatgatc
     3301 gatgatcact agatctgcat accgaggcgg cttatttcga gtacatacat gtatagagat
     3361 ccgttttcga tgtcttagcg ttttgttcag taccccagca agtcttcttg cttcttggtg
     3421 ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg tggacatcta aataccctcg
     3481 ttcctggagt gttttcagta aaagcatccc ccactctact gcggggtgtg caagtgcttg
     3541 ttggatcgct agccgaaatt gatatagttt atctttggaa ttgggaaatt tttctaatgt
     3601 ttcctgataa taacgaactt cttctatcag ccggtcatgg ataccaatta cgtaacgaag
     3661 tcattcttgg taaagtactt ttgtcagctt tgatttgctt tcgctctcaa attcgctatt
     3721 cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc aatttccgat agtcttgtgt
     3781 ctcttctatc cgtttccacc gcttttcagt aatctggtta cagctcaagc gcaaaattgc
     3841 tagataattt ttttctttta ttggcaaaat ctgctcctct ctaaatagca attcaggaaa
     3901 caattcaaag aatagtgttc gactgtctcc taaaatctcg atttctgccg gatcctttct
     3961 ttgcttcaat aattggatga acatctcaga aaaggactgc tctccatcat ctgcaaaaaa
     4021 atgcggaaaa tctttcaaaa agcaaaacag cagatatctt acttttcttt ctgaaccaaa
     4081 gatctgtgct tttttataag aaaaagaaag gtggtactcg ccaaaccact ttctcaatcg
     4141 ctcttgcgta gaacgatcgt acttctgctc gtaaggttca ttcaatagca gatttttcag
     4201 taaacaaaac gggggtgatt ggatcagaaa aacaaacaag agataaggtt cgctatatcc
     4261 ttgatcataa actaactgaa cggttttctt atgaagaatc agctgaatgg gacagtcgct
     4321 ttccgccaaa cgtttcagat gccgatccac tgttttaaca tcgattttca gttcttcagc
     4381 taaatcagct tttcgccaga tcaaatcttt cattagattg attagtgaaa ataaattctg
     4441 tgcatttttt gataatagtt tttgccatct catcgatcat ttctcacctg atttctaaac
     4501 atattgtttg atcaaaatgg gttcactcct aaaaagataa aaaactccct ttctatttat
     4561 ttaaatacgc aaatcttcct cattattttt tattttactc aatttaatcg tattctcatt
     4621 tcaaaacgaa tgtactttaa aaaaacataa taagatcact ttgcttgtag gatgtattcc
     4681 cttccattac aatgaaataa atagcgattt tatgagaagg tgatgtgaaa atggaagaaa
     4741 aaatagaaga atccaaacaa aaaatcgatc agttgatata agaattagaa aaagcggtca
     4801 tcggcaaacg ttcaactatc caattgatga tcgtggccct attagcaggt ggtcatgtct
     4861 tattcgaaga tattcccggt gtaggtaaaa cgttactggt caaagcacta gcaaaagctg
     4921 tacagggaac cttcagcaga gtccaatgta ctcctgatct gctgcctagt gatattcttg
     4981 gtttttccgt atacaattca caatcaaaag agtttgaatt tcgtccggga ccgatcttta
     5041 ccacgatctt gttagcagat gagatcaatc gtacgactcc tcgtactcag tcagcacttt
     5101 tagaagcaat ggccgagaat catgcaacga tcgacaacaa tacataccct ctagacaatc
     5161 atttttttgt cttagctacg caaaatccaa tcgagtacga aggaacatat cctttgccgg
     5221 aagcacagct cgatcgtttt ttattccgac tacaaatcgg ttatccttct tttgatgacg
     5281 aacttttgct acttttggat aaattcgaaa aagtgttgga taacttaaat gaagtattga
     5341 acagttatga aatagaagaa ataaaaacaa atgtggcgaa tgtctttgtc agtcccgaag
     5401 tggcatctta tgccttgcag ttagtgtcag caacaagaag tcatgctgcc atccagcttg
     5461 gcatcagtcc acgaggaagc ctttccttta ttcaggcagc aaaagcttat gctttaatcc
     5521 atgggagaaa ttacgtcacg cccaaagatt tgcaggattt agttccttac gtgttttccc
     5581 atcgcctgat tttttacgat cgttcattga aggaagacga aaagaaacaa atcattcata
     5641 ctcttgttgc acaaattcct attcctgtga ggtagattga ggtagacaat ggaaaaaatc
     5701 aaagattatt tcattaattt tgtgttattt ctggtatatt tcatcattgt gctttttgct
     5761 cttgtattca acaattcttt aggctggttc ttgttggcct tttttactct ttatgtatca
     5821 tggagcttga tttcattaag cagctttcta aagaaacttt cggttacttg tacattgcag
     5881 ccactcgttt atcgcaaaaa aagtatgcag gttatttttt ccatagcaaa aaagagaact
     5941 ttttctttac ctctccctcg tttacaaatc ggcttcccag caatctttgc agaaaaaaac
     6001 aagagatttt gattcttaca aataaaccgc aagaagtcca attgctttgg cagccaaaag
     6061 aaagaggatg ccatgaaaca ttaactgtca tttttacagc ctatgatagt ctaggacttt
     6121 tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac tgttctgcct gctttttgta
     6181 agattcaagc agaaaaatta cagagagttc tggaaaaaaa acagcagctg aacgcgtacc
     6241 aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc aggtgattct ttcaaccgaa
     6301 tcgattggaa attgtctgct catactcaag agtggttata ccgtgaatac gattatcaag
     6361 aagaagaatg ttctcctctt ttttgctttt ggggttcgcc cagtccaaaa tttgaacctc
     6421 tgctagactt gtatttttct ttatggcatt tgagaaaaga aaagcagccg gaacttctga
     6481 tattaggcaa ccgcgccttt catggcaaag accccggtca tacctatttt gcttctttgg
     6541 aagctggcga tgagaaagct tttttcgcac acttgaaaaa atatgcaaaa aaacaaatcg
     6601 tcctctttgt tcctgagaat tctcctgaag tctcagaagc tattgaaaca ttgtcaaaag
     6661 atcgaacggt ttatcttgtt tatttcgtag aaaaacaact catggtccaa gaaaaagaca
     6721 agatatgttc attgccagga ggtgaatgga ttgacgatta aacgggaaaa atggctgcgt
     6781 ggcgtttact cctttgtgat actaagtgta ggtgctccga tatttgtagt agctaatcaa
     6841 ttgcaaaaca gctaccttct tatcctaact attggtgtcc tatgccttat tgtctgctgt
     6901 attcctaaaa aatgggtacg tttgctgctt tctttgccag taatgatagg ttgtttgttt
     6961 ttatattttc cttcgaagac attttccata ttatggatct tacagttttt ttcgtcagtc
     7021 acagaggaat tcttccatct atcccaaggt aaactttatt atttgccaga aaagacagct
     7081 ttttttctca taatgttgct gatctattta tttattacat tgaccgtgga ttacgactat
     7141 tggtacgcac cctttctttc tttgatggct tacttcatga tgcttaccgt ttttcggaaa
     7201 aaagatttac tgtacgaaat gattgcggta gtaactgttt tgttcgtgta tctggcagca
     7261 aggcaatttt tctccatccg gttgttgtcg ggaaacactc gattccagtc attgactaca
     7321 gttctgctta tttgtttctt aacttttagc gctatcttgc ctttatatct tccgaaagta
     7381 caccaatctc tcgaggaaac gagtgaaccg atccgagaat atcttaatga tgaagggctt
     7441 tatgacacac tccatgagta tcaattaacc ggaagtgcaa gaacaggctt cagtgagaat
     7501 gatgaacagc ttggtggacc tttatatgat aatggcgaag ttgtttttac agcgaaccaa
     7561 aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt acaccggttc tggatggata
     7621 gaagatcagg acgcacccat ccaaccaatc caagaattcc ctgttgacat cacgagctac
     7681 caaaccgtta tagaagacaa agaaaacatt acattgaccc taaaaaaaca agttttctta
     7741 ccttatcctt atggaaatac taccttgact gatttttcat tagctagtgg acaaacgctt
     7801 tactatttgc ctgaaagcca gcgattcatt cctgtcccga atgaatcgac acgttctgca
     7861 actttacaaa cagaaaggtt agtttttacg agagaagaat taaaaagcag tcagttaaaa
     7921 gctgatgatt tagaaaatca gcagacaaat cttcaattgc caaaaagttt gcctaaacgt
     7981 attgaggact tggcggtcga attgaccaaa aatgaagcaa ctttaattcg taaagtcgaa
     8041 gctgtctaac agtatttaaa aacaagcgga aatttccgct attccaaaac ggataccggg
     8101 catactccaa aagaacacga ttatgtggat tatttcctct ttgattcaaa agtcggctat
     8161 tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa cacttggtat cccagctcgc
     8221 tggacaaaag gttttacaaa tgggctcaga acaggcacag ataatcaagg gaatgaggaa
     8281 tacagcattc tcaatagtca tgctcattct tggccagagg tatactttcc tggatttggc
     8341 tggcttccat ttgaaccaac cccttcattt gccaatccaa tgggttcaca accagttgct
     8401 gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa atgaaagcga aaatatggca
     8461 gaaactattt ccagtgagag atctgaggtc attccatcag aagaaacaac actcacacca
     8521 gcttataaaa tcgtcttatt cagccttgga gtgtgtttat ccgtcttgtt gttctttcta
     8581 ttgttattca gaaaatctct gcgctggaca agttatctta tctatcttca tttttttgct
     8641 tctactaata cgattgcata tcaaaaactt cttaaccctt tggaaacatt ggtaccgcgc
     8701 aaacccgcag aatctttgca ggaatatagc ctgcgaatag aacaagaatt caagctagat
     8761 ctgcgtttca ttcgattaac tactcaatat gaagcagaaa tatatggacg acaagcagat
     8821 ccggtaaaat tcgataaaaa aacctattta gaaataacgc atataataag aaaaatggta
     8881 tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat aagataaaat ttctggagaa
     8941 tctacttctg gaatgccgag aaccagctga ttgagtatcg attactcgaa aaaaaggttg
     9001 tgacacgttt tttgtcacaa ccttttttca ttattatctg attttcaatg tcaaagcatt
     9061 tagagctaca actaccgtac ttaacgacat caagacagca ccaactgctg gacttaatat
     9121 gataccaatt ggcgcaagaa ttccggctgc tagcggaatt gcaagaatat tgtaacctgc
     9181 cccccaccag aggttctgga tcattttctt tcgcgtttgc ttggctagat caagaaaatg
     9241 caaaatatct tttggatcgc tgtttgtcaa tacgacatcc gcagaatcga ttgcgatatc
     9301 tgtccctgca ccgattgcca tcccgattga agcacgggct aaacttggcg catcattgat
     9361 cccatcaccc accatgatta cttttttccc ttggtcaagg tatttctgga caacagcttc
     9421 tttatcatct ggtaataaac cgccataata ttcttcgatc cctaaataat ctgctactgc
     9481 ttgggcagcg tttttattgt caccagtaag catgacagga gtgatttttc tttctttcaa
     9541 tgttcggata aattcttttg cttctgtttt tactacgtca cctaaagcaa cgattgcagc
     9601 tagatgattt tctaaaatca ggaagctgat ggtatttcct tgttcttggt aaggtttcaa
     9661 taatgcttgt tctacgttta atccgagacg ctcaacttct ttttcattaa ctattttcac
     9721 ttgttgtttt ttgactgttg cctctagccc gactcctgaa agatttttta gattttcagc
     9781 ttgataaggc ttgatttcat gttctttcaa ataattcata atgccaacag ccaatggatg
     9841 attggcattc gcttccaagg ctcctagata ttgaaggatt tcatttttat tgaacgcatc
     9901 atcaagtact tcgacacccg ttacagtaaa ttttccttct gttagtgttc ctgttttgtc
     9961 cagcatgatc acatctagat cattggcttg ctccagtgca ttgcggtttt tcaaaagtaa
    10021 tccgttttta gctgctattg atgtggaacg agcaacaact aatgggatag ctaaacctag
    10081 agcatgagga caggcgatga taaagactgt taccatacgt tctaatgcat taggaagatc
    10141 tgtcaagaac aaccaggcga tgaatgccag gatacccaca attaatgcga cataaaacag
    10201 ccattttgcc actttgtcag ataatgactc tagcttggat ttttctcctt gtgcttttcg
    10261 caccatttcc ataaccttcg ctagataacc attttcacca gttccagtta cttcgatttc
    10321 gatcgttcca tccccattga tagaaccgcc aatcactttg tcattggctt gttttttgat
    10381 tcctcttgat tcgccagtca cagctgattc gtcaacaatt gtttcacctt tcaagattac
    10441 accatctgtt ggcattttat caccagaccg gacgatcaaa cgatcacctt cgtttacttc
    10501 tttcaatgaa actgtctctt cttttccatc tttcgtcaag cgtttcactg attctggcag
    10561 taattctgct agtttttgta aagcattgct ggcattcgac acagcattca tttcaatcca
    10621 gtgacctagt agcataataa cgatcaaagt agccaattcc cagaagaaat ccatgacgtg
    10681 tgtatgtgga ttgagcagat ttgcgataaa cgaatagaca ctataaatat atgcaactgt
    10741 aatccccatc gcgatcagtg tcatcatagc aggacttttt tgtttcaatt ccatcttagc
    10801 tccacttaaa aatggctgac cgccatagat aaatagtata gttgctaaga tcaatacgag
    10861 ccaatcagaa ccaggaaacg ttacttgaaa tggaaattcc attcccatca ttggtgaaaa
    10921 aagaatgatt gggatagcta ggataagcga tagccaaaat ttttgtttga aattccccat
    10981 gtgcatggaa tgatccatgc cgccgtgttc gtgatccatg tgcatcgaat ggtccatttg
    11041 tttgctgttt gctatatctc catggttatg tcccatgtgc atggaatgat ccatctgact
    11101 atggtcatgt ttcatctcca tctgtttttc atgagattct gtactttctt tgtttactac
    11161 ttctttttta tgctcatgtt ttttctccat atcgttccca ttcattttta ctccatccct
    11221 tctcttactt tttcatgtgt cgatttaagc acagggagtt caacaataca ctgacggaac
    11281 taaacgccat cgctcctcct gcaatgattg gattcaaaaa gcctagtgcg gcaaaaggaa
    11341 taccaatcgt attatagaca aaagcccaga aaagattttg tttgattttt ctcaatgtca
    11401 acctagacaa ctcgattgtt tgtgcaatgg atgccaaact gctattcatc agcgtcacat
    11461 cggctgtttc catcgcaatg tccgttccac ttcccattgc cataccgaca tcagctaatg
    11521 ctaaggccgg tgcatcattg attccatcgc ctgccatacc gacttttttg ccatctttct
    11581 gaagtttttc tacgtaggct gctttatcct ctggaagtac ttcagcaaag atatgctttg
    11641 gatcaatacc aacttgttta ccaatcgttt cggctgccag tttgttgtct cctgtcagca
    11701 taaaaacatc taatccttta ttctggagct gcttgattgc ttgtttgact tctagtttga
    11761 tttgatcagc cacggcaatc aacccgatca cttgcttttc atcagctaaa aacatgactg
    11821 tttttccctg ctgttctaat tctaacgcgt gttcttggta ttcatcaaat gataggttca
    11881 attcaattaa tcgtttacgt gtacccgcaa aatagcgtac tccgttaatc gtaccgctga
    11941 ttccagcacc tgggtgggct gtaaaatcaa tcatatcgta tgttgctgct tcttgcagtt
    12001 ttccgtattc cacgattgct ttacctagtg gatgttcaga agcttgttct aaagtataaa
    12061 aaatagatag gacttcttta gaaccgacta gatctgtaac tttgggcttt ccttctgtaa
    12121 tcgttccagt tttatccaaa acaatgctgt ctaagtgagc agctgcttct aatgcttctc
    12181 cgcctttaat taaaattcca tttcgtgcac caacacccgt tcctaccata atagctgttg
    12241 gagtcgctaa acctaatgca catggacacg caatgactaa tacagagaca ctatggatca
    12301 atgcgagttg ccaatcacca gtgatcaaac ctgtagctat gagcgtgata aacgcgatga
    12361 ctaatacgat cggaacaaaa atccctgaga tccgatctgc gattttttgg attggggctt
    12421 tgctcccttg agcatcttcc accatttgaa tgatttgcgc taatactgtc tgcttgccga
    12481 cttgtgtaac ttccatgtga agtagaccat tcgtattgat tgtcccgcca aagagcgtgt
    12541 catccggatt cttttctaca ggaagatttt caccagtaag catactttca tctatcgcac
    12601 tgcttcctga aataattcga ccatctgctg gaatctgctc accaggacgg atgactagtt
    12661 gatcaccaac gactacttct tcaatcgcta acgtttcttc tttcccgttt cttatcactt
    12721 gggcggtttt tgtttgaaga gacatcaatt gtttgattgc attacctgtt ttcgtttttg
    12781 ctgtatgttc caaatatttg ccgagcaaaa tcagcgtgat gatcatactg ctgctttcaa
    12841 aataaagatc ttgggggtgt ccacggaaaa atccgttgta aatgctcaat gcaaaggcag
    12901 ccgatgttcc aattgctacc aatacatcca tatttggtgc tttcgtcttg attgcatggt
    12961 acgcaccttt ataaaaacga gcaccgacat aaaattggac aggagcagac agcactaact
    13021 ggacgattgg aaaatgaaaa aagtgaacaa tcgccgcatg gcttcctaac atcatagcaa
    13081 tcattgacaa catcaacggc aaagtcaaaa ccgtactcaa tataagatcg aatagcattt
    13141 ttttcaaata cgcttgcttt tcttctgcaa ttttttgttt gtgggcttca tcgtacaaaa
    13201 ttgcaccata gccgatgttt tctacgcttt ggattaattt ttcagtggtc gtcccttcat
    13261 atttgacact tgctttttca gtggccaagt tgactgtggc attgaccaca ccaggttgtc
    13321 cgttcagctc tttttcgatc ctagcagaac aatttgcaca agtcatacct gtaatgacga
    13381 acgtatccat tttggtttct gctgttgcca tcaaatcacc tctgctttat aacccaatcc
    13441 attgattgct tgacaaatct tttcggattg aacttttgtt tcatcaaact tgaccgtacc
    13501 gtttgctttt ttcaaattta ctttcacttt ttgcacgccg tcaagtgcgc ttactgtttc
    13561 ttctactctt gctgcacaat gattgcagct cataccttcg attgaaaatt gttgtttcat
    13621 tttttcttcc tcctattgat gttgtttaca ttcacattga cctgggatac agttacattc
    13681 gatcgtatct actggttgct tttgttccag ttgtttcaaa atctcattga tatcttcttg
    13741 agtcaaagtg gcttcttcta ctagatccgc aatcgtctct ccaatccttt ttgcacagat
    13801 atgggaaaaa agattttccg tcgcactgcg aactgtttcc atctccgaga cagctggata
    13861 ataaatgaat ttttttcctt cttgttctgt ccagatcact tcttttttta ccaaacgacc
    13921 cagcaaagtt ttgatcgttg ctggtttcca atccatcgaa tcagctaaga tctgcgtgat
    13981 ttcttgggct gtcgtctgtc caagtgtcca aataacacgc atgatctccc actctgaatc
    14041 actgatcttt actggcgttt tgactttttc catttatttc acacctttcg tttacaaatg
    14101 taatcattat cttatgaata cagattacac ttgtaaacaa aaactgtcaa ttatttttgc
    14161 tctctatttt caatttagtt aaaaattctt gtttctctcg tcttgtttta aggatgatca
    14221 gtttatttct tgcattagct acttggatca gctgctgtat tttcggttca ttgttttctt
    14281 caaaatgcca gataaaagat aaaaattcta agtattccct gtttagtttc tccgaaaatg
    14341 attcaggcat atctggccga gattttttgt ttatctttct ttttagagaa cgccaaacta
    14401 ctcggtagat ggcgagataa cgcggcactt taagccaaat gatcttatct gcttctttaa
    14461 tcctttcctc taatgtagaa gtataatttc cttcaacgat ccatgacgga ttagatacca
    14521 taaacaattg ctgttcttgc aaaaaccact tttttgcctg aatactgtag tctgttgtat
    14581 gccataaaag gtctagcggc agtagcggaa agtcggtgat ttctttgatc ttccttgcga
    14641 gggtcgattt tcccgaccca ctttgtccaa tcacgatgat cttcattctt ctccctcact
    14701 tctctttgga atttggttcg atcataccac ttataacgcc gcaaaaaaac aagggactgt
    14761 gacaaaagtc gtgtcaaagt cccttgtttc gaata
//
LOCUS       DACCVH010000066        14375 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.066, whole genome shotgun sequence.
ACCESSION   DACCVH010000066 DACCVH010000000
VERSION     DACCVH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.066"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..831)
                     /locus_tag="IVV98_002105"
     CDS             complement(<1..831)
                     /locus_tag="IVV98_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7807736.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     V"
     gene            complement(973..1152)
                     /locus_tag="IVV98_002106"
                     /pseudo
     CDS             complement(973..1152)
                     /locus_tag="IVV98_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(1356..1715)
                     /locus_tag="IVV98_002107"
     CDS             complement(1356..1715)
                     /locus_tag="IVV98_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP7807737.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(1745..2086)
                     /locus_tag="IVV98_002108"
     CDS             complement(1745..2086)
                     /locus_tag="IVV98_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807738.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(2083..2757)
                     /locus_tag="IVV98_002109"
     CDS             complement(2083..2757)
                     /locus_tag="IVV98_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7807739.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(3933..5231)
                     /gene="asnS"
                     /locus_tag="IVV98_002110"
     CDS             complement(3933..5231)
                     /gene="asnS"
                     /locus_tag="IVV98_002110"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP7807740.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(5271..6461)
                     /locus_tag="IVV98_002111"
     CDS             complement(5271..6461)
                     /locus_tag="IVV98_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7807741.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(6482..7009)
                     /locus_tag="IVV98_002112"
     CDS             complement(6482..7009)
                     /locus_tag="IVV98_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7807742.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(7056..9845)
                     /locus_tag="IVV98_002113"
     CDS             complement(7056..9845)
                     /locus_tag="IVV98_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7807743.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(9992..10192)
                     /locus_tag="IVV98_002114"
     CDS             complement(9992..10192)
                     /locus_tag="IVV98_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7807744.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(10645..10965)
                     /locus_tag="IVV98_002115"
     CDS             complement(10645..10965)
                     /locus_tag="IVV98_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807745.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(11468..12586)
                     /locus_tag="IVV98_002116"
     CDS             complement(11468..12586)
                     /locus_tag="IVV98_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807746.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            13057..14364
                     /locus_tag="IVV98_002117"
     CDS             13057..14364
                     /locus_tag="IVV98_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP7807747.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         4086 a         3068 c         2527 g         4694 t
ORIGIN      
        1 tacttgaact aaaaatggtt tatttttatt gataaatccg cttaatactg tttcaccaac
       61 atatacagat ttagggactg attctcctgt aagtgctgac gtatcgacta atgattctcc
      121 ttcgatgatc gttccatcta acggtacacg ttcaccaggc ttcacaagta caaactgacc
      181 gatctgcacg tcttcagggt tcacggtcat caatccttcc gtcgtctgca cgtgagctgt
      241 ttctggacgg atcgccatca attcgcgaat cgattttctt gaatgactga ctgccaatcc
      301 ttggaaatac tcgccgattt gataaaatag catcactgct acggcttctg gatattcacc
      361 gatcaacata gcgccaatcg tagcaacaga cataagaaaa ttctcatcaa agatttttcc
      421 tttgacgata ttcatcactg ccttcttcac tacatcatat cctatcagca gataaatcaa
      481 taaataccct atcaagcgaa ttggttcatt aaaatcaaat aatagcaata aagcgatacc
      541 tgcaagggaa aataaaatcc ggaacagcgt atttctctct ttttcatttc catgttcaga
      601 tactttttcc ttatctattt ctgttacttt gacatctggt tctaattcct tcactacttt
      661 ttttgtttct tgttcaatcg tagccaaatg atcttcctct gcgtcaatcg ttagttttcc
      721 agaagtgaag tttaccgttg cttccttgac tccattgatc ttctgaactc ctttttcgat
      781 tttcattgca cagttcgcac aatctaaacc ttctaatctg taacttttca ttttaatgac
      841 ctcctcgcct caacatatga acatctcttc ataactaatt ataaatgaat ggttattcat
      901 atgtcaaggt atccgaaaga aaaaatgaaa aacatctgca tcggaaaatt tcttccatac
      961 agatgttttg gcttattctt tctttttctc ttcgatcatt gcccctgctc ttatccaacc
     1021 cgcacttgcc ttcttgatct tgacaggata gcaactaagt ttgaagcctg ttgctggcaa
     1081 tttgtctaaa ttcattaatt tttcgatagg acaatatctt ttttcaatcc ctgcaaaatg
     1141 tccttcccag atattcgaag ctccactacg ctttcaaaaa tatagaaaga gttctttaat
     1201 gaaaattatt tcaactttcc ataaacagta atcccatata aataaaagac gtaaaagtca
     1261 catgggagaa cttatacagg aaaacacata gagtcaggtg aaatacatgt atcccacctg
     1321 actctatgcg ttttctaacc tttattattc tctttttata caatttctgc accgaatggc
     1381 atcaacgcca atcgagcaag tttgaaagat tgcttggcaa aaggtatccc tatgatcgtg
     1441 atacatagaa ggatgccgct gacgacatgt gcgagagcaa ttggtaggcc tgaaacgatc
     1501 agccagatga tattaacgat caatgacatg ccagactggt gataaattac ttctttgcca
     1561 aaaggcgcaa aagaaaggga ggcgatctta aaacattgca taccgattgg gatacctatg
     1621 atcgtgatac accaaagtat ccccgctgct aaccagctaa gaccaccgat tagtccgccg
     1681 aatataaacc agatgacatt tcctaaacaa ctcattgtat ttctccttct attactgttt
     1741 ttgattaaaa ctgggcaaaa attgatttta ttcttctttt tttagcttcc agcatcaagt
     1801 attctgcaaa ttttttttgg atttcttccg tattttcttt tgttactaat gtgtgttgga
     1861 ttagttttcc tgatggtcgc tgatccaccc gttcttctga ctgttgcacg tccgcttgcg
     1921 caaatccgat aatccgtttt tcttttgtta cagcaacgag caatagttta ttcttatcat
     1981 ttaggtcagc tgccgttttt gcttttacga atgattctgg atgatcagta atcagctgat
     2041 tgatttgagg taaatcttct tttactgccc accgtatttc catcatttct cacttttctt
     2101 tcgctcattt ttatctccac taaaaaaatc gactgcggca attgcatcta tccagctttg
     2161 tgcaatgatc tcatgtccgc caatcgttgg gtggacccca tcttctcttg tatatttcga
     2221 aaaaccataa gcaatcccta aagcattgaa tatgccatct aaaggaacca gcaatgcgcc
     2281 atattcctta gcaagtttac gaacaatttg gattttaggg tctaagtctt tacgccagcc
     2341 atgacggtcg tcggttatag gaagtacaaa cggctccatc aagatgatgt tgcagatttc
     2401 cgctgtttga agttcattta gtaattttcg ataaacggat tcaaattgct gcgcagattt
     2461 ctcagttccg aatatagcct gatcgctagt attatgccag gtatcattga ttccgatcaa
     2521 aatcgataca tagtcaggtt gtaaagctaa acaatcttct tgccagcgta cttgcagatc
     2581 tgcaattttg tctcctccta tcccacggtt catgcattca aatttcatcg ttggatattg
     2641 ggagattagt tttccggcaa tcaaaagtgg ataaccttta cctagatcag ttgcttctgc
     2701 tcggtctctt cctgcgtctg taatgctgtc accgataaat aatatacgtt ttttcatttg
     2761 tcaaaaactc ctttttgaat aaaacgatga ttttcttcct tatattatcc cataagccct
     2821 atcaagacga aagagaaaat atatgtataa aaaatgacac cagcctagtc ccttcaatca
     2881 attgaatgaa cgctcatcaa gtgtctagtt ttttatactt tttttcttaa cgtgccggat
     2941 tccccttgat tccttcgttg tttggtccag agaaatcgat cacacctaag cttccgtcaa
     3001 tcagaccact gatgacgcca tcagaacata tatttatagg ctcatctaag acttccagta
     3061 aatgttcttt tactaatatc tcttctagat tgcttgggat agattggtca taactttatc
     3121 tggtccgatg atttcaagga tgaattaaac ttacatatgg atcattgcat gctgaaaata
     3181 cggacctact ccatcttcga atgttactat tagtttgttt tcaggtacta gatgctgctt
     3241 tatttcaaca gcagaagcat catcaaatca gatttccatt tgaataacct tctttgtata
     3301 tgtttgattg attgcgattt cgttatagaa ccttgtgaat caaatagcaa tttcttttgc
     3361 tttcttctct tgtctgctgg aaacttcctt tatcccgtat tttaaaaaaa gaactgcgag
     3421 agttcgcagt tctttttttt aaataaacgt tgctctccgg ccaactcctc ggtcacaagt
     3481 cacaatagtc atcaaacatg aaaaactgtt ttttgaaatt actccttgtg actcggagct
     3541 gaacggcagg cgcacaacct cttgatataa acggtgttca atcagctgac cctcgatatt
     3601 agctaaaaaa acggtaaaat atgagaagct atttttccgt tttgtttctc taatactcag
     3661 gtcaaggcac tgatttcaca acctcttcct taaacggtgt tcaaaagcca gtttctcggt
     3721 attaagccaa atttatgcaa aaatgtggaa agccatttcc acaaaatttt tcttaatact
     3781 cgaaactaaa cagctttttc acaacctctc cactaaacgg tattcaaaag cttacatctg
     3841 cggtaataag tcccgccaat tcaaaaacat gaacagctgt ttttgcttgg ctgttctaat
     3901 tacttgatgc agaacagctt tttcatcacc tcttatggat aaattcggtt caacaaacgt
     3961 gggaatggaa tagcttcacg tacatggtcg ataccagcaa tccaagtgac tgttcgttca
     4021 aggcctagac caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc aagataccat
     4081 gaatattctt tttcatccaa accgtgatta cggatttgtt ctagcaagaa atcatagtct
     4141 gttgcccgtt cgcttccgcc aataatttca ccgtaacctt ctggtgcgat catatctgca
     4201 caaattacca cgtcttctct tgttggatgt ggtttcatgt agaatggctt gatggctttt
     4261 ggatagttta ggataaagac aggctgttcg aatgaattcg caatgaacgt ttcatgaggt
     4321 gaaccaaagt cttcgcccca ttcgatgtca tcaaatccat ttttcttcag taattcgatt
     4381 gcatcatcgt aagtaatacg agggaatggc aattttgtat aagtttttaa gacttctttg
     4441 tctcgtccta gtacatctaa tgcatattcg caatgatcta aaacattttg tactaagaat
     4501 gctacatatt gttcctgtac ttctaaactt tcttcttgat gagtgaaagc catttctggt
     4561 tcgatcatcc agaattcgat caaatgacgt cgtgtttttg atttttcagc acggaaagtc
     4621 ggaccgaatg aaaagacttt tccgaaagcc atagcagcag cttccatgta taattggcca
     4681 ctttgagata aataagcttt ttgatcaaag taatttgttt cgaatagatc cgtagtgcct
     4741 tctggtgcag aaccagtcaa gatcggcgga tcgattttga caaaatgatg ttgattaaag
     4801 aattcatacg ttgcacgaat gatttcattt ctgatctgca taatcgcatg ttgtcttgaa
     4861 gaacgcagcc ataaatgacg atgatccatc aagaaatctg ttccgtgttc ttttggtgtg
     4921 atcggataat cgtggctctc gcttaccact tccacatttg taattccgat ttcataacca
     4981 aattttgaac gactgtcttc acggatttct ccagttacta acacggatgt ttcttggtgt
     5041 agatttttag ctgtttggaa aacttcttcc gacacttcgc tttttacaac tacaccttgg
     5101 aaaaaggctg ttccgtctct taattgtaaa aatgcgattt ttccgcttga tcgcttattt
     5161 gcgacccaag cgccgattgt tactgtttct cccacatggt ttttcgaatc gatgatttga
     5221 atttgttcca cgtatgactc tccttttata ttccttgaat ttcttcagga ttaattttga
     5281 cttttactct caataaattg cttgattctg cgtaccgctt cttctaacgt agcgcgatca
     5341 gtggcataac tcatgcggac attttctggt gccccaaagc cttcgccagt cacaagcgct
     5401 acccctgttt cttctaaaag atcttctacc cattgtgtga cattttcata cttacacatg
     5461 cgtagcgttt cttttacatt aggaaaaaga tagaaagctc cttgcggctt ttcaagagaa
     5521 acacccggca gttctgccac aagcggatat aacgtattca ggcgttcttc aaaggcgttc
     5581 cgcatttctt ctactgtatc ttgctcacct ttcaatgctt caacagctgc atattgactg
     5641 actgctgtcg gattgctagt tgattgggaa gcaacagcga tcattccatt gatgatcaca
     5701 ggatttccca ccgcataacc aatgcgccag cctgtcatcg catatgtttt agacacgccg
     5761 ttgatgatga tggtctgatt tttgattgct tctgaaatcg ttgcaattgg agtaaactca
     5821 ttgccattat aaactaaacg gccataaata tcatcagcaa ctatcaaaat atcatttttt
     5881 actgcccatt caccgattgc ctgcagttca ttcttgctat aaatcattcc agtcggattc
     5941 gatggagaat tgatgattac ggcttttgtt ttttctgaac gtgcttgttc tagctgttca
     6001 acagtaactt tccagctatt ggattcttcc cctttcacaa agacaggaag tccttctgcc
     6061 agttttactt gctcaccgta actgacccag taaggcacag gaatgatgac ttcatcttgc
     6121 gggtcaagga tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc tgttacgact
     6181 gtttgtgaag gttcatagac aagtccatag tttttcttca gataatcaac gattgcctgt
     6241 cgaagctctg ggattcctgc tgttggtgta taatagctag ctttcccatt gcggattgct
     6301 tcgattgctg cttcttggat gttttctggt gtcgcaaaat ccggttctcc cacagtcaaa
     6361 ctcagcacat ctctgccttt tgcttttaat gccttggcct ttgccgcagc tgccaaagtg
     6421 acagacggtt ctaatcgttt tgttcttttt gataactcca tcccattcat tcctttacct
     6481 tttaaattcc cttgattgtc ttgacttcat ctccagattc aaagccaatc aggtaataat
     6541 tcagtttccc atttgtttct tttcctacta cttcccacac aggctgatca tcatacatcc
     6601 ctaaagcagc tttttcgatt tggatttcag gatgggccgc agcaattgtc tgttttgctt
     6661 cgttttcagt cagtcccttt gtttgatcca atacttttac tttttcacca gatttaggaa
     6721 tgataacggc gatttctttt cctttatcat ttgtacctgt cagtgaaaag tatgtcttct
     6781 ttcgagtaaa ccaataaaaa tgatcggttt cctcaagatt tgcatatttc tttgcgattt
     6841 ctactgcttc tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa aaaatcgagc
     6901 tgatcacgat gaccgctaat aaaaatacga tcaagccaag taacacgcga ttaatcgttt
     6961 tttcctttgt ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt ccttttcatt
     7021 atagcagatt ttaattatga aaaaagacag ctcctctaac ttccttcttc atttttcttt
     7081 aagaattcat ggatatcctg atagatttcc tccatagcta gctctttgat cggtactttt
     7141 ttcggtaatg catggatgat ccgtgcgcca tattttgcag tgactagtct tcgatccaaa
     7201 ataagcaata cgccacgatc tgtctccgtc cttatcaagc gacctaatgc ttggcgtaac
     7261 ttcaaagctg ctttaggtac ggattcctgg taaaaaggat tgatcccctc tgattctaaa
     7321 taagcgttcc tagctttgac catcgggcga agcggattat cgaagggtaa acgtgtgact
     7381 acaacgatct gcaaagcatc tccaggcaaa tctacacctt cccaaaagct gtcagcgcca
     7441 aacaatacgc ttttttctga caaaatgaag cgtttcaaaa gcttctcccg gcttccacca
     7501 aacccttgag ctagtatttc tcgtcctttt tctagcatag acagatgcat tttctgatag
     7561 accttctgca aaacatcatg agaagtgaat aacacaagta ttggccgatc ttcttgttcg
     7621 atcagacctg taagtgctgt ctctaaataa tcgatatatg cttgattgct gacttgatgg
     7681 acggcaggtg cctcttttgg cacatagatc cttgcctgtt tctcataatc ataaggagag
     7741 gcaatcactt taagaggtgc tgcttcaatg ccaagcctct tagagagata gtgtcgatta
     7801 gggccgatct tcagcgttcc tccaatataa agaatacgat catatcgagg ataccaaaca
     7861 gtcgacggca acatagccgc ttgaaaatca tggagatgaa aaatcatctg ctgcgctgtg
     7921 ttcccaggaa cgaaccaatg gatcaaatga tctcgccagt cttccagcca ttgatccatc
     7981 agcaagtatt gcttgtctaa ttgatcaaat aggctatata aacttgctaa atcgatccgc
     8041 atctggtttg tccagctttc ttggataatc tcaaaagtca gacgcatttg tgactgtagc
     8101 tgctggatct cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga ttccagtggc
     8161 agctgatcca acatctcttt tgtcatcatg acttcttctg gatactgtcc gttaggttgc
     8221 ttgccgctca ctaaactcat taatccttct gccatacaaa tctgtgcttc gcatagcgca
     8281 gaaagttctt ctcgataaat cgataaccag cgtaaggctt catgttcttt cggtaaatag
     8341 ctttgtattc ggtcaaacag ctgatttggt tcttctaatt gctggatttg tttatggaaa
     8401 tagttaatac ttaatcgttt gtcatttact ttttcagcga tttccggcaa atgatgtact
     8461 tcatcgatca acaaaaatgg actagctgga agcaatggtt cttttcgctg tgtttcttgt
     8521 actaaaaacg catgattgac aatcaaaaaa ttactttgcc tgattttctt ttgcaagaaa
     8581 cgaacaaagt cttgttcgta aaatgactga tttcttgcta aaaatccaat acctctgtgc
     8641 gcgatatctg caaagaatga atggttcaaa tttgttaaat gtaattcatc caaatcacca
     8701 gtcttcgttt gcgtcagcca aactaagacc gccatttgat acaaagcata ttgtttttgt
     8761 tctggcggtt ccacaagtgt gcctttaaaa cgctgcaaat caatatagtg gcgatagctt
     8821 ttgataatta caggttgtat gggctgatct agcaattgat tcagcaatgg aatgtctttt
     8881 tctatgatct gctgctgcaa aactagcgaa acggtactga tgacagcggg tttttcaggt
     8941 gtagccaaat aactcaatgg cagcagataa ccgattgttt tacccattcc tgtagctgct
     9001 tcgatcatca aatcttttga ttcatctttt gtgaaatggt cgtagaccgc attcatcagt
     9061 ctgttctgtt cttttcgata catcagtgtt ttaccaaaca ttttttcttt tgcttgtttt
     9121 tttcttggat atgtccgctc gccataatgg acggatgtga atagttccac ttcttttttc
     9181 tgcaaagcta gcccatcgac gatttctaat gagggatcaa gtggctctgg tttttctttc
     9241 atttcttcaa tcacatgata aatgaaacga ctcgtatcca tacctgtgtg tctacttaat
     9301 cgcgcaatct gctctaacgt gatgattggc aattttctca tccgttcttc gatcagcaaa
     9361 agaagttgac ctgtcacttc ggcatcacta tctgcctgat gaggattctc atgaataaat
     9421 ccaaggcttt ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa gaaaatttgt
     9481 gcaagttcta ctgtatcgat gcctggtatc ttcaaactag gaagtccgca tcgcatgagt
     9541 tcatggttca aaaaattata atcaaaataa atattatgcg cgacaaatat ggtgtctgcc
     9601 aaaagattgt aaatcgtttg ggcgacatct tcgaaataag gcgctttttg gacgcgttga
     9661 ttcgtgatcc ctgttaaatg ctggatttgt tttgaaatct tccgccctgg atgaatatcg
     9721 atcgaaaaac gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa ttggatgatc
     9781 cgatcttctt ttggattcgt cccagtcgtt tcgatatcaa cgactgcata agttcttggt
     9841 ttcaaaatat cttcctcttc tcctgcctct aatgttcttt tgaaattata ctacaaagtg
     9901 cagaaaaata ctctcatcgc tttttaaaga aaatagacaa aaacgcccag acacgcaaat
     9961 gtctgggcgt ttatttttta gtataggtta attaagcttt agtaacgttt gttgcttgag
    10021 gtccgcgttg gccttcttca acatcgaaag ttactgcttg gccttcttct aaagttttga
    10081 atccgtcgcc ttggatagct gagaaatgaa cgaatacatc gtttccgttt tctgcagtga
    10141 tgaatccaaa tcctttttct gagttaaacc attttactgt acctgtttcc ataataaaaa
    10201 tcctccttgt gtatcaacac atattttgca attacttgaa tggtgtatat ctggaagatg
    10261 tttatttgaa acaagctacc acagattacc gaacaaaaac tactcctata gtatatcata
    10321 ccgtttacaa aaaagctaga gtttttcgac tttttttatt aaaaaaagtt ttctcagcga
    10381 ttacataaag tgaaaaaccg aacttttttt taaaataaac gacatattgt tcagttggtg
    10441 tttttttgct ctgatgttct tttttaaact aaaaaaatta ttctttctga ctacttatcg
    10501 gttctgtttc aacggtcgag gctggggaag attctttagt aggtctgatg ttctcatggt
    10561 atttctgata gcctatgaca gttaccagaa gaacaaggca aaccaatacg accaacgaga
    10621 ttagtttttc ttttttgctc atatctatac ctcataaata acaggatgat gtccatcata
    10681 tttctgagta tgagtaaaag caaaagctgc agctgtagaa tgtaagaaat gccagcaact
    10741 ttcataatca caggtcggac agtaccaaaa gtaaccaaat cttggctgca aagaccgttc
    10801 ttctgtttca ggaatcgcag aatcaagatc tggtgtctgt acataaacat ttttgtacag
    10861 acgtgtgcct gtaataggaa accgctgtgt ttcttcagca aaaactggct gacttgttaa
    10921 acttagggat agagacagca aacaccataa cagtcttttt ttcataaaga cctccttatc
    10981 gataagtttt tcccaattaa aatcatatct caagaacgcc cgttattcac attttgttca
    11041 taaatgatgt tttttgtatc ataatcgtca aaaagaggtc gtgaccacgt cacaacctct
    11101 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
    11161 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
    11221 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
    11281 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
    11341 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggcaaaa
    11401 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
    11461 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
    11521 ccaaaataaa cacttttccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
    11581 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
    11641 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
    11701 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
    11761 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
    11821 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
    11881 tttctggtag agcaaataaa taaatcggcc attgttctgg attttcgaaa gaatccttca
    11941 agtacgtatc aactgcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
    12001 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
    12061 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
    12121 ctggtagaga tacttctttt acttgtttgt tgctgacttc atacaatttc atggagtcgc
    12181 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
    12241 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
    12301 aggtttggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
    12361 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
    12421 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
    12481 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
    12541 cttctgaagt caattgtgac aataattctt tatccttttt tgccataaac gtacccctcc
    12601 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
    12661 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
    12721 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
    12781 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
    12841 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
    12901 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta accttccata acgtgcgttc
    12961 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
    13021 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
    13081 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
    13141 caagctgaag atactttcaa agtaaatgca aaagcagcct ttgctgtaga tgcgcaaagc
    13201 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
    13261 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag ggaaactatc atgggatgat
    13321 aaagtttcaa tttcagatta tgcagaaaat ttgagtgtca ccccagattt atcaaatgtt
    13381 cctttgcata aagaaaacac ctacaccgtt aaagaattat tcgactctgc aatcatccag
    13441 tcagccaacg cttcaatggt tgccttggca gaaaaaatct ctggcagcga agcaaaattc
    13501 actgaacgaa tgaaagaaca attgaaagat tggggtatca aagatgcaac gatcgttaat
    13561 gcatcaggac tgaataactc ttatcttggc gaaaaccgac cagaaggtac tggagaaaac
    13621 gacgaaaatc aaatgtctgc tcaagatgtg gctatcgttg cccgtcattt gatcttggat
    13681 tttccagaaa tactggatgt atctagcact acgacacaaa tgtttggcga aaacacgcaa
    13741 tcaccagtag aaatggtcaa ctggaactgg atgctcccag gattcgtgaa ttataaagaa
    13801 ggcgtggacg gattaaaaac tggtacgact gaacttgcag gagcctgttt cgtcggtacg
    13861 atcactaaaa acgatcaacg aatcatcact gtcgtattga atgcagacgg ccatgcggaa
    13921 aacccaagtg cccgtttcaa tgaaacagct cgcttaatgg attattgcta cgacaattgg
    13981 tcagaaaaag agcttggaaa agccaatgca agtatcccta gtctaaaaac cattgatgta
    14041 aaagacggaa aagaatcaac agtgcccgtt gtgcttaaaa gtcctgtaaa agtatgggta
    14101 cggaacgata tggatactgg aaaattaaca atcacaccaa ctcttgacaa aaaacaagtc
    14161 actgacaatg agatccaagc acctatggat aaaggaacaa aaatcggtac cgcaacgatc
    14221 accttggcag aagataaatt aggttatctt gaagacaaca acgcgccatc cacagaaatc
    14281 atcacggata aaaccgtaga aaaagcaaat attttcgtta ttggctggcg acgcgtcgca
    14341 gaatttttcg gtaacttgtt ttaattgaac aaaaa
//
LOCUS       DACCVH010000067        14139 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.067, whole genome shotgun sequence.
ACCESSION   DACCVH010000067 DACCVH010000000
VERSION     DACCVH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.067"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(51..3704)
                     /gene="rpoC"
                     /locus_tag="IVV98_002118"
     CDS             complement(51..3704)
                     /gene="rpoC"
                     /locus_tag="IVV98_002118"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP7807748.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="IVV98_002119"
     CDS             complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="IVV98_002119"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP7807749.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8128..9096
                     /locus_tag="IVV98_002120"
     CDS             8128..9096
                     /locus_tag="IVV98_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7807750.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9114..10019
                     /locus_tag="IVV98_002121"
     CDS             9114..10019
                     /locus_tag="IVV98_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7807751.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10016..10822
                     /locus_tag="IVV98_002122"
     CDS             10016..10822
                     /locus_tag="IVV98_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7807752.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10979..11947
                     /locus_tag="IVV98_002123"
     CDS             10979..11947
                     /locus_tag="IVV98_002123"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP7807753.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12264..12788)
                     /locus_tag="IVV98_002124"
     CDS             complement(12264..12788)
                     /locus_tag="IVV98_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP7807754.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13075..>14139
                     /gene="scm"
                     /locus_tag="IVV98_002125"
     CDS             13075..>14139
                     /gene="scm"
                     /locus_tag="IVV98_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP7807755.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         4003 a         3047 c         2793 g         4296 t
ORIGIN      
        1 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
       61 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
      121 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
      181 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
      241 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
      301 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
      361 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
      421 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
      481 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
      541 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
      601 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
      661 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
      721 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
      781 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
      841 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
      901 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
      961 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
     1021 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
     1081 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
     1141 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
     1201 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
     1261 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
     1321 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
     1381 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
     1441 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
     1501 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
     1561 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
     1621 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
     1681 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
     1741 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
     1801 tctgttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
     1861 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
     1921 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
     1981 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
     2041 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
     2101 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
     2161 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
     2221 atatcttggg aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
     2281 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
     2341 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
     2401 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
     2461 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
     2521 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
     2581 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
     2641 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
     2701 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
     2761 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
     2821 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
     2881 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
     2941 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
     3001 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
     3061 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
     3121 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
     3181 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
     3241 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
     3301 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
     3361 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
     3421 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
     3481 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
     3541 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
     3601 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
     3661 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
     3721 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
     3781 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
     3841 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
     3901 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
     3961 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
     4021 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
     4081 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
     4141 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
     4201 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
     4261 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
     4321 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
     4381 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
     4441 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
     4501 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
     4561 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
     4621 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
     4681 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
     4741 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
     4801 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
     4861 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
     4921 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
     4981 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
     5041 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
     5101 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
     5161 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
     5221 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
     5281 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
     5341 tcaacgacac cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
     5401 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
     5461 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
     5581 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
     5641 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
     5701 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
     5761 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
     5821 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
     5881 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt
     5941 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
     6001 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
     6061 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
     6121 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
     6181 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
     6241 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
     6301 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
     6361 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
     6421 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
     6481 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
     6541 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
     6601 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
     6661 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
     6721 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
     6781 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
     6841 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
     6901 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
     6961 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
     7021 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
     7081 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
     7141 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
     7201 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
     7261 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
     7321 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
     7381 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
     7441 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
     7501 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
     7561 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
     7621 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
     7681 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
     7741 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
     7801 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
     7861 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
     7921 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
     7981 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
     8041 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
     8101 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
     8161 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
     8221 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
     8281 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
     8341 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
     8401 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
     8461 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
     8521 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
     8581 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
     8641 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
     8701 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
     8761 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
     8821 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
     8881 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
     8941 ggtaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
     9001 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
     9061 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
     9121 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
     9181 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
     9241 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
     9301 cttgtcttct aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca
     9361 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
     9421 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
     9481 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
     9541 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
     9601 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
     9661 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
     9721 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
     9781 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
     9841 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
     9901 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
     9961 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    10021 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    10081 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    10141 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    10201 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    10261 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    10321 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    10381 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    10441 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    10501 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    10561 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    10621 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    10681 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    10741 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    10801 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    10861 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    10921 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    10981 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    11041 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    11101 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    11161 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    11221 acaaacgatg ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg
    11281 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    11341 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    11401 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    11461 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    11521 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    11581 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    11641 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    11701 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    11761 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    11821 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    11881 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    11941 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    12001 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    12061 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    12121 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    12181 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    12241 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    12301 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    12361 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    12421 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    12481 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    12541 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    12601 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    12661 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    12721 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    12781 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    12841 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    12901 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    12961 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    13021 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    13081 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    13141 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    13201 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    13261 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    13321 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    13381 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    13441 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    13501 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    13561 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    13621 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    13681 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    13741 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    13801 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    13861 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    13921 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    13981 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    14041 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    14101 acagatacat ctaccacaag tgatagctca gattcatca
//
LOCUS       DACCVH010000068        14130 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.068, whole genome shotgun sequence.
ACCESSION   DACCVH010000068 DACCVH010000000
VERSION     DACCVH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.068"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..244)
                     /locus_tag="IVV98_002126"
     CDS             complement(<1..244)
                     /locus_tag="IVV98_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP7807756.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     AFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="IVV98_002127"
     CDS             complement(237..1829)
                     /locus_tag="IVV98_002127"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP7807757.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2339..3064)
                     /locus_tag="IVV98_002128"
     CDS             complement(2339..3064)
                     /locus_tag="IVV98_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807758.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3218..3544)
                     /locus_tag="IVV98_002129"
     CDS             complement(3218..3544)
                     /locus_tag="IVV98_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807759.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3581..3946)
                     /locus_tag="IVV98_002130"
     CDS             complement(3581..3946)
                     /locus_tag="IVV98_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAP7807760.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3983..4198)
                     /locus_tag="IVV98_002131"
     CDS             complement(3983..4198)
                     /locus_tag="IVV98_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807761.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4327..4662
                     /locus_tag="IVV98_002132"
     CDS             4327..4662
                     /locus_tag="IVV98_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807762.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4738..6735)
                     /locus_tag="IVV98_002133"
     CDS             complement(4738..6735)
                     /locus_tag="IVV98_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807763.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6833..7108)
                     /locus_tag="IVV98_002134"
     CDS             complement(6833..7108)
                     /locus_tag="IVV98_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7807764.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7340..8074
                     /locus_tag="IVV98_002135"
     CDS             7340..8074
                     /locus_tag="IVV98_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807765.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8113..9255
                     /locus_tag="IVV98_002136"
     CDS             8113..9255
                     /locus_tag="IVV98_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7807766.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(9883..10368)
                     /locus_tag="IVV98_002137"
     CDS             complement(9883..10368)
                     /locus_tag="IVV98_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HAP7807767.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(10370..11134)
                     /locus_tag="IVV98_002138"
                     /pseudo
     CDS             complement(10370..11134)
                     /locus_tag="IVV98_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11304..12497)
                     /locus_tag="IVV98_002139"
     CDS             complement(11304..12497)
                     /locus_tag="IVV98_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7807768.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12581..12784)
                     /locus_tag="IVV98_002140"
     CDS             complement(12581..12784)
                     /locus_tag="IVV98_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP7807769.1"
                     /translation="MMNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVI
                     MNGNRIQIKRKQFEKIIDTLDTI"
     gene            13041..13283
                     /locus_tag="IVV98_002141"
     CDS             13041..13283
                     /locus_tag="IVV98_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807770.1"
                     /translation="MAHQPSGSAQTECVRMPYDAPPLSCGHIYQGAIRPPGKHRNGER
                     VSRFMLPGPVRQFVTIAWMSLISRRRFMASSRHTCG"
     gene            complement(13205..13438)
                     /locus_tag="IVV98_002142"
     CDS             complement(13205..13438)
                     /locus_tag="IVV98_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7807771.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(13445..13876)
                     /locus_tag="IVV98_002143"
     CDS             complement(13445..13876)
                     /locus_tag="IVV98_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7807772.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4295 a         2895 c         2271 g         4669 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat gctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacatat gattttttca taaaaaaaca gtactgtcta gtagtataaa
     2101 atatacaaat ttcttaaaaa ttttttcact aaaatcacta cctgaaacag tctaaaacac
     2161 ttatatatca acgtttaatg aaactatctc cgtttcattt cagatacaaa taaatatagt
     2221 cgggctccaa atccgaaaaa aaataccccc agtagcttat cctaagctac tggagatgta
     2281 taagtacggt catataacaa cggggtaggg taaataaatg aaaaagatgg aagaatcatt
     2341 attcaataac ttttttaaat acttcgttgt aatcagttac ctgtccgttc ttaaatacca
     2401 cagaataatc ttttttccca ttttcaagta accgaagtgg aatatcttta ccaactttct
     2461 ctgtcactgc attactgata cctgttagat tagctaataa atctgataaa gattgagcat
     2521 ctgtagaaat ctctgtatca gtatttatcg tgattccttt atcttcattt acaagtttcc
     2581 aagtaggtgg tatagctgtg tatgtttcta caaatgaatt aagtttttca ttaagtgact
     2641 tctcttttat atttccatct aaaaactctg tatatatggc ttgagctata ctaaaacaaa
     2701 gctggccttg ttctaataat tttacatcat tagttagtaa agctgtgttc acgttatcaa
     2761 tcgcttcaag aagagtatct ttggtgtccc taacagcttt aggtgtgcct tctggaattt
     2821 ccctacttga tacctcgtcc attttatctt ccataaaccc cttaaaatca tatctttctc
     2881 ccaaatccat agaagttttt gagaaagctt tcatttctga gtctatttct tcaataatat
     2941 ttaacatgtc tgatacatat tgtttaggct gattcgtttt taatctatat gtggtaaata
     3001 tctcaattcc tccaattatc aataaaattg ccaaacaaat ccataataat tttttctttt
     3061 tcatttttcc tcctatacac tgctgttata acagtgacta atgtaaagat tttcccagca
     3121 atcatcagac tattatttac agggaatcaa aaaaactcct tagtaagctt acacctttag
     3181 gagttcctgt ttgaacggta tgcataatac atttaaatca atttaacatt aacacctcag
     3241 tatatggtat ctctacatat acacggtctt tttttggata gtactcgaca tttatattga
     3301 tagcacttcc attgtctaac gtagctttag cccggtacgt gttatcacca ttatcatgag
     3361 tgatcgtcac atcatcacat gtccgattta agttatactg ttcttgtaaa atctgagtta
     3421 ccaatggtac agatgacttc tctagtccag atgaacccgt cattcttgaa aaaattatac
     3481 ctataatagc caatacaacg atacctataa tgacaaactt cttattcata tttactttat
     3541 tcaacttttt atctcctatc tccaaaatga ttttctctca tcagtaactc attgacatcc
     3601 ccaatagtac accaaagatg gctccagcta cccctgctat catcaaaatc gtacccattt
     3661 gttcatcttt ctctcgatat aagtaaccca taataacagc aacagcacca aataccacag
     3721 gaataaatgc taatgatact accatagaaa tccaaccaat aatcaaatac agcttccctg
     3781 tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct
     3841 ttactgtgtc tgttccggtt gtctcatctg tttcttgtaa tgctccgcaa aactggcaat
     3901 acttactttc atttgttatt tctttaccac attttctaca atacatgtct tctcctccta
     3961 aaatcattca attgcttatt agctaactgt ttactttatt aaatacatca gaaaacagct
     4021 catttattgg tacacttaat atctcagaaa gcattttcat ttgatagggt ttaggaatcg
     4081 ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt ttggctaact
     4141 cagtttggga aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga
     4201 ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca taaaatatat
     4261 aaatacttca aatgtcatta caaatacaac aacttgttgt actctactga gaaggggggt
     4321 gtattaatga aacagaagca atatgcaaag gtcattagag aaaagcgaaa agcactcggg
     4381 tggacacaaa aagaattagc taaaaaaatc ttctctacac aacaggcagt agcaagatgg
     4441 gaaaattctg taacagaacc taacctcgat agcttaacag ctctttctag agccctagga
     4501 acccctgtaa gccattttct agacaatgtt gacatagatt atgaggaaga gtttttggct
     4561 ctctatcgct ctcttagtac tgaagatgca attcgaacaa ttgactatat gaagctatta
     4621 aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt gaaaaataaa taacccaccg
     4681 aactttaacg gtgggtgtat tgagatgaaa taagattaag agctatggat aacctgtcta
     4741 gtttaatata attgggtctc ttctattcct tactctccgt ccatcatctc ttgttacact
     4801 tgtaaattga taaataggaa ctaattcaac tcctgataat atcaattctt ttattacttc
     4861 atctatccct gcccctttcg ctagatatac taaaaaacta ctgcttgctt tcacattgta
     4921 tagtttctta atatccttag aagctcgttc aagagtgaat ccttgtttaa caaagtagcc
     4981 tctgttttct attaaagcat ttttcacgct gttatccctg acatttcgta ggcgttcaca
     5041 aacagtgtta ataagttctt tttctgtcat tagatatgtc ccttgccacg ataagccctg
     5101 taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc ttgctaagtt ctgatcggga
     5161 attttgagga aatactcttt tagcctcttt ttcgttaaaa catatcttaa cccattcata
     5221 agaaaaatat tgatatgtaa aatgaaattt ttccagaagt ggaaggatat cttcattcaa
     5281 tttttgaatc acagaagttg cattaaaaac gtctaatcga tagacattgc ttctcttatg
     5341 tttaaagttt cctaacgctt tctcttcctt taacctattt aggtattcga gcatcttcaa
     5401 aggaacatct tcatcatcta atttttttat caatcctata aaagtcataa gtgatagtaa
     5461 cttattacat ttatctatgt cataagtttt accatagtaa gaactcattt ttttagctaa
     5521 ttgttccccc gacaaaatac aagtcacact ttccttacta tcatcaaaaa aattaacatc
     5581 agaaagcaag acatcataga cacgtcgcat ttcctctaga taattcctta ttgtcctgaa
     5641 aagtttgtct ttcattgatt caagagtgtc aaaaagtact tttgattcct ctttcaattt
     5701 tcgaaaatgt gtaggataca agtctaggtt ctctaatagc caattaaatg tttctacccg
     5761 actgtctttc tttaaaatta gcatcacaac tccaataaaa ttttcactga tatcacaatt
     5821 actggaatga caataaaaaa tggaatgccc agttttactg gtaaaaatac tagcagaggg
     5881 attatgatcg ttgtgaaaca gacatcttaa gtttttactt gacttaagta atttattcat
     5941 atcaatggtt aacaatcttt cataaatctc attaaaagac atgtcggagg aatcaaacag
     6001 gcagtcttta aaccactgtt tcatttcttc tttgtcgtca ttttttatca acttaacaaa
     6061 atcggtttca ttgactagtt catactctct ccctgaatca ctttgacaat ttttagaaca
     6121 tgtcatggta aaatcaatcg gaagctcagt aatatctaac atgttgtctt cattaattat
     6181 tatcactgca tctgacttat atcctccaaa aaacattcta ttcgaagcat ttacattgtc
     6241 atcacacccg gggatgttct ttttcaagta ttcgtaaaca gcaaccattt taccatagtc
     6301 agtaattgct tcttttaata gaaagacaat cttgtatttt tctagatttt cagagtaccg
     6361 aatacttttt tgtatcgcaa acgcagaatt atgaactaaa ttgatagata aaaccttttc
     6421 tatgcttaag tatctactat catctttact caaatctact accttcccct tctcatcttt
     6481 aacagtgtta tcgacatcca gaataattac tctggtttcc acaaaactct ccttgtcatt
     6541 gcctttattc tttgtcttgc ttggaataaa tgattgtgat gaatttagta tctctacaaa
     6601 ctcatctctt gtaacttctc tatagttatc taaacaccta tctcttacat cagttttttc
     6661 tttttttgta actggcttct ctaataattt ttctttatct acataaattg gaatattaat
     6721 cattgatgtt tccatttgtg tttcctcctt ataaaattct gttaaagact aaaacataca
     6781 gataataaaa acaaactctt tattactata tgttttagtc ttatttgttt actcaacctt
     6841 tataccgttc catgaaacta tcaatatcag attttttaaa tctaatgacc gtatcaattt
     6901 ttataacagg taacccgtat tgagaaacat attttctaat cgttcctact gatacaccta
     6961 gatattcact tgcctgctga tagtccatat actctagagt gactccagaa ataatgtctt
     7021 ctagcatagg ctttagcact gtaattatct ctttcacttg ttgttcaact tgtatagaaa
     7081 caatgctatc aatgatttgt agagacatat ttccccctcc tttcgtgatt gcttgaacaa
     7141 attttctaag aattatcttc gtattttttg ctcaaaataa aagtattttg ttattaaccg
     7201 attaatcaaa caaaaaatga ttaccagttc atcgacatac acataatacc tcgataaaaa
     7261 aggggtgtca atagttttgt aaaatttatt tacaacaccc cttttttgag gtatactaat
     7321 tttaggaggt gtggtcaata tgataaaacg tccaccaata aattatttag aacgaaaaaa
     7381 gatactcgga acaaaaataa aagctataag aaagagtaaa aaattaacac aaccagcatt
     7441 tggtcttatg attaacaacg gtcaattaat tgacaaaaag actatctacg aatgggagaa
     7501 gggaacctat ttaccaatac cagagcgatt atcccgaatt gctgatttgg gaaatatgag
     7561 tatagaggag ttagtttgtg gcaatgtaga agaatatatt ttgggaatta ttctttatag
     7621 agatagcatt gtactagatg gtataacatt tccagataaa aacctgttcc agcatcttcg
     7681 tcaacagttc ccaccagtac actctaattt agatacatgg ctggatagat attccaaatt
     7741 agaaccagag atgcaagaat ttattgctaa caagacttgt aataaagtta aaaatgaaaa
     7801 aattagtctt ttcaatatct taaaaataga agaattattc atcaatgcta ttgtagaaga
     7861 atttgacaat aacattcttt tcctcactag cagtatagaa gaactactag aaagaatggt
     7921 agatgaatgg ctacctattc aattgaaaga catgtcttat cccgaagaag ctgtgagaga
     7981 aattactgat aatataaaca agctagaaca aacgatttca tcaattggga aaaaatacac
     8041 taagaaaaaa atgaagggag gtgataccat ctagtggtaa gtactccttg taaactaaga
     8101 ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg
     8161 atgtataaag gacacattgc caccgatcca cgaactggtg aaaaaataaa tactacgaga
     8221 agaggtttta gtagcaaaca agaagctcaa aaagattatg acgagtacag acatcaaata
     8281 ttatacggtg ttaaaaagaa agcacctgat atgacatttg aagacctgta taatgaatgg
     8341 ataactcatc agcgtaccag tgttaaagct tcaacaatcg caatctcagt aagatacgca
     8401 aataatcaaa tacttccagc atttggtaag cttaaactat cgaatatctc tgtcccatat
     8461 tgtcaaaaag tggtagatga atggcacagt aaatatgaaa gttacgatta tatgagaaaa
     8521 cagactgcac aaattttacg ctacggggtt gcaatgcaat atattgacaa taatcctatg
     8581 gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa
     8641 gaggagctta ataatttact ggatgctttt aaagattttg gtaacatgaa acaatacgcc
     8701 ttcttcagat tattggcata cacaggtatg agaaagagtg aagtactcgc tttacagtgg
     8761 aaagacatag acacgtttaa taaagaacta catgtcaata aaactcttgc tgtagatgaa
     8821 tttggtaaag ttataattca atctccgaaa acaagagctt ctagacgagt tatctcttta
     8881 gatactgaga ctctttctat cctcaacaac tggaaattac agcaaaaaga agagtattta
     8941 aaacttggat acaatactag ctctaaagag caacatgttt ttacaacagt taaaaacact
     9001 ctatacattc caaacactgt taatgattgg ttaagatata ttttgaaaaa atataacttg
     9061 cctcgtatta cacctcatgg gtttagacat acacatgcta gtttattatt agaagcagga
     9121 gaatctgtca aggtagttca acaacgatta gggcatgaaa atagtaaagt gacattagac
     9181 atctatgcac atattacaaa taatgcacct aagaaaacag gtcaagactt tgctgatatg
     9241 atggctcatc agtaaaagag ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca
     9301 aaaaagctag aacccttata tatcaagggt tctagctcct ataacaggtt tacccaacac
     9361 tgccttccaa tgactctttt gggaatcaga ggaaagaatc aggctttata gagatatttc
     9421 atctaacaaa ttactttaga ctgacagtat atatcagcag gtactgtcat cgggaacgta
     9481 gccaatatcg tatccaaaac agcaggtaga gaagctattt gaggattcaa gttattctat
     9541 ttcaaccatg aagttaagtt cattaaaaat aaagatagtt ggtatttcaa taatttttgt
     9601 atagagttaa tcactttatt gatgctaatt catcttgatt ggtattataa tcgtattcaa
     9661 gttgcgtggc gtgcttttgc tagaaaatat ataactgttc tttataaaga aatataagga
     9721 ttaaacattt tttatcatag agttttactt atctatagaa ttatgtctgt tcctaattca
     9781 gtttgatgaa ttaactgata aaaaaatatc tactatttaa agatacaggg ataagtaagt
     9841 aaaaaaataa catgtcatta gatagtagac agttccaact ctttatttac cttttttgta
     9901 tgctgcactg tcaatccaag ttcctaaatt gttgtatcca tcatcactta tataatcata
     9961 ttggccatca ataatttcgt caaaccacaa atattctcca tctggttttt gcccaattat
    10021 tttaattact gattgactag tagttgtcat ctggttaaaa tcttttattt tacctatatt
    10081 aacggccaaa atagcatttc ctcgcttata actctcctgg atttcatatt taacatattc
    10141 tcgatcaaga gtttctttac ctatcagcac cacagtcact gatgttccaa ttaattgatt
    10201 atctatccag ttttttatag caatatctcc attacgttta actttctcaa attcagcctt
    10261 atctacaaaa ccagcttcct ttgttcctcg caaagtccag ctgtttctaa ctaccattgc
    10321 tcttgttaca tctgcataat ggaaactaaa aaaaaccctt ctcaccatat taatcctcct
    10381 gaatactatt tattaaactg acaatttgtt caactttttt atctacttct ccttcagtat
    10441 ctaatttttc tagcgcttga aatttacttt ttaaggaatc atcaaaataa tcactgaaat
    10501 tctcttgaat cttatcaaac aaaaccttac ttgcaccttt ggtaaatcca atcggaacta
    10561 ctatattttc attttgaaca gataattcaa attcttcaat cattccatct gctgtaacta
    10621 tttcacctga ttcaagtttg tttccaaaaa caaaaatact aatcccagac tctgcaataa
    10681 tgttttctcg atatcttctc cactcatgag gcatatcaag gggaagtggt cttaaagaaa
    10741 gtacgtcttg tatgttattt tttcttaaat ttcttctctg ctttagaact cctgaaacaa
    10801 tactattacc aattccaagt ccgtaacctg atactattct ataaccggat tcagaaagcc
    10861 tatatgctaa tttctcgaca aattttaatc ctttcgattc agatgtaaat ggagtataat
    10921 caacagcact tcccgaaata aaaatagttt ttctcaaata cttttttcta atacttttca
    10981 aaatatcagt aatctcagaa taatcatcta cttcaacaac gtttatcgaa aatctggaca
    11041 aatcattgat ttgtagtctt ctttttgtca gttcataatt atatctctct tgatcaaaaa
    11101 aatcctcaga atcgacaaaa ttttccttta aaattatatg ggattttaga ttatcttttt
    11161 agaagttctt gaatgtcggt atagcccgtg tttccgggct tttccggcat ttttgatatt
    11221 gttagatact tacaaatgtt cttattacct ctcaccattt ccccctcaaa agtagtaaat
    11281 ggagtagtaa aaccggcctt gtgtcaggct gccagccgtt ccatttctgc ccttgcggaa
    11341 tcgaatgtgg cgtgtgcata atagttcagc gtcatggtga tattggaatg tcccataatg
    11401 tactgcaagg ctttggggtt cattcccgca ttggctaacc gggtgcagaa tgtatgacgc
    11461 atagcatggg gcgtcgtcgt tttcggcaac gcttcttcat ggctcttgtt gtacttcttc
    11521 acaagcctgc caaacatccc gccataatct accgccgtca tgggatagcc gttctgtttg
    11581 agaaacagga aattggcata cccgtcaata atgaacggct ttgcaccttt gcggtttttt
    11641 atcactcgct ggaacgcctg atacacttcc tcattcatgg ggatttttct gacgccgctt
    11701 tgggtcttgg gttcgtcaat atagtaaccg acgccggtat ttctcaaaag ctggtggctc
    11761 acgatgatta cccggttttc aaaatccaaa tctttgtccg tcagtccgca cagttccgaa
    11821 atgcgaagcc ctgtccccag cagaataacg attgcgtcat aatgcttttg gtaaacctta
    11881 tcaccttgaa taaaggacag aaaactttct tcctgtgctg gtgtaagagg cacctttggt
    11941 tccgtatcgt cgtccagaac gtcactaagc tggaagtcaa acgggttttt tcggatgcaa
    12001 tcgtcctgta tggcggtgta aaaagccgct ttcagggaac gcttgtcgtt attgatggtc
    12061 ttataagaaa ggcccttttc tttcatccga agcgcccatt cctttgcgtc ggacagcttc
    12121 acactgtcaa tcgggcagct ccccagccga tcttgttcca gaatacgcat cagccgttcc
    12181 cggcccagtt tggtgttgtg cttcacattg ccccggtgcc tgatctgctt ggcgtagagc
    12241 tggcagacgg tcattttctt gccgatggtg tctatcccgt cgtcaaggtc tttctggatt
    12301 tctttctcct tttcccggag tgaaatatcc tcccgtttac ctgccggggt cttatccgta
    12361 ggcactaact tccatgagta aacaaactgc ggttttccaa aggtatcaac atatttgtaa
    12421 gcatatcgtc cgtcttttct ctggctctct ccagaccgca aaacgcgatt tttgctgtct
    12481 cgtctttttt ctgacatctc gtcatgctcc tttccatgac ggaaagagcc gcatatatgc
    12541 ttataaatta ttataacata tctgcggccc tttttcacta ttagattgtg tccaaagtgt
    12601 caattatttt ctcaaactgc ttgcgtttga tctggatgcg gttgccattc ataatgaccc
    12661 agccagaggc cggattttcc tcggccagct tacgcaattt gttttctccg atacggaaat
    12721 atttagacgc ttcctcaatc gtcagcgtgt atttttccca aataggcaca tcatggttca
    12781 taatgcagcc ccctttcaca aattcaaagg tttgtgtgat ttaggggcat agacggacgg
    12841 ctgctggcac agctccacgg gactttcacc cccgcgtggt tctcacgcgg ccctacccat
    12901 tgcctgcgac gcttttaacg ctcggactgt ggctataagg gagtatcata gtcctgcctg
    12961 tacgtcgtcg cccgcaagcc gccacgctca cattgcggcg tggtgttcct cgctccgctt
    13021 ttcccgtagg gaaaagtatc atggcgcacc agccgtccgg ctcggcacag acagaatgtg
    13081 tccgtatgcc ctatgatgcg ccgccgttat cttgcgggca tatttatcaa ggtgcgatca
    13141 ggccaccggg aaaacaccga aacggggaaa gggtaagccg tttcatgctg ccggggccgg
    13201 ttcgtcagtt cgtgacgata gcgtggatga gcttgatttc cagacggcgc ttcatggcct
    13261 cgtccagaca cacatgcgga tagccgtttt cgtcatagag cgtccgggta cacagcttgt
    13321 tcatgtaacc gctgtaatac tgcaaaacgc gctctacggc tccggcatcc ccagcgcggg
    13381 cggcctcgat caccgaaagg ggcaaaagct caatgccctt gtagttcggg ttcttcatcc
    13441 gcgtctaacc tcccttcggc atcaacgcct ttagctgttt ccgcagctcc gataaggtat
    13501 ttgtcctgtg ccgctgaacg gcactccggg acattcccac aaggccgccg atctcaccat
    13561 ctgccatatc cagaacacag tgcaggatta aaatactctg ctccatgctg ggcagcgcgg
    13621 caaaggcttc ggcaacaagc tcattgttga tatgtaggtc atagccatgc gacgaaaacg
    13681 taaagctgtc gctggggtag tgatctactg tacagagctt gtccaaatct gcctgtgaca
    13741 aagagcttag tgacacttca cggtcacggc ggcgcttcat ttcagccaag tagcttttgg
    13801 cctcgttacg cagtaccgtc ttgcaaaaag catcgaacat gcaccgcgct tcatagtcgc
    13861 gggggatagc atccatcttc tcaccccctt tctgtggggg acttaggtgg ttctctccct
    13921 ttccgctaac aagactttga caaggccgcc agctacccgc taaatacctc ctttttgaaa
    13981 atttctcaaa aaattttttt ggggacagcc gggccgcaaa agacgacaaa aatcgcccgg
    14041 caggtcgcaa acctaccggg cgagaaaatg ctttgctatg ctgctgattt acatggtata
    14101 gtacatactc ataaccggaa tagccctgtg
//
LOCUS       DACCVH010000069        13762 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.069, whole genome shotgun sequence.
ACCESSION   DACCVH010000069 DACCVH010000000
VERSION     DACCVH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.069"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..2115
                     /gene="acm"
                     /locus_tag="IVV98_002144"
     CDS             <1..2115
                     /gene="acm"
                     /locus_tag="IVV98_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP7807773.1"
                     /translation="ITSLIPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSFD
                     EKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNENI
                     KNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYYK
                     TGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQKV
                     YRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQINF
                     ENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPNV
                     TFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSNE
                     LKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPVP
                     DAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVVT
                     NENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTNL
                     PKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEKT
                     EREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSFA
                     VIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2387..2872)
                     /locus_tag="IVV98_002145"
     CDS             complement(2387..2872)
                     /locus_tag="IVV98_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP7807774.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            3352..3993
                     /locus_tag="IVV98_002146"
     CDS             3352..3993
                     /locus_tag="IVV98_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7807775.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4012..4647
                     /locus_tag="IVV98_002147"
     CDS             4012..4647
                     /locus_tag="IVV98_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7807776.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4665..5480
                     /locus_tag="IVV98_002148"
     CDS             4665..5480
                     /locus_tag="IVV98_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7807777.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5799..7235
                     /locus_tag="IVV98_002149"
     CDS             5799..7235
                     /locus_tag="IVV98_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7807778.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7424..9856
                     /locus_tag="IVV98_002150"
     CDS             7424..9856
                     /locus_tag="IVV98_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP7807779.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            10086..11153
                     /gene="rlmN"
                     /locus_tag="IVV98_002151"
     CDS             10086..11153
                     /gene="rlmN"
                     /locus_tag="IVV98_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP7807780.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11346..12449)
                     /locus_tag="IVV98_002152"
     CDS             complement(11346..12449)
                     /locus_tag="IVV98_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7807781.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13001..13549
                     /gene="aac(6')"
                     /locus_tag="IVV98_002153"
     CDS             13001..13549
                     /gene="aac(6')"
                     /locus_tag="IVV98_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP7807782.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4700 a         2303 c         2917 g         3842 t
ORIGIN      
        1 ataacatcac tgattcctgt tcatgtctat gcggatgcag gcagagatat cagcagtaat
       61 gtcacttcgt tgaccgtgga cccaacgaat attacagatg gaggaaacat aaaagtaaaa
      121 ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg attatctttg gatcaattgg
      181 ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag aaatcccatt aatgattgaa
      241 aataaaaatg ttggaacttt aacggtcaga aaagattctg cgcaggttgt gtttaatgaa
      301 aatattaaaa acctagactc agtagaaggt tgggggcaat ttgagataca ggccagaaac
      361 gtaaccgata ccggtgaaga aaatacggga ccattcaccg tgacgagcgg tgataaaaca
      421 gctactgtaa atgtgacaaa gccagcttct ggttcttctt ctagcgtttt ttattataaa
      481 acaggagaca tgctacctga agatactaag cacattcgat ggtttttgaa tattaacaat
      541 aacggcactt atgttgaaca accagttaaa atcagtgatg aaatccaaag tggacaaaga
      601 ttagatccaa gtacgtttga aattaatcaa atacacttag gtgaacagaa ggtttataga
      661 ggagaagagg gaatccaaca atttttacaa gatttcccca gcgctacatt taatttttca
      721 gtaactgata attacattga aataactata ccaaaaaact ttgtcaatct taggaaaata
      781 atggtgagtt ataagacgat catagaaaac ccagaacaaa taaattttga gaatcattcg
      841 gaagcttggt ttaaagaatt taataaacct gctgttgatg gagaaagttt caatcataca
      901 gttaaaaata tttcagcttc tggtggagtc aacggtacag ttagaggcga attgaagatt
      961 ttcaaatata tcaatgacac agagattggt atcccaaatg tgactttcga attaagacga
     1021 gcagatgaac agcctattca aggacagtct agtatcctgt tgacttcgaa tgaacaggga
     1081 gaagctagta tcaaaggcct gcaagtagga gactatgttg taaaagaaaa agaagcaccc
     1141 aattggattg attttgatcc actaagttca aatgaactca aattctccat aaacgaaaat
     1201 gatacagagg gagtcagttt acctatttat aacaagaaaa aggttacgaa catcacagca
     1261 actaaaattt ggaacggtgg aaccactcca agaccgagta tttattttaa attattcaga
     1321 gcaagtacaa acaattggga accagttcct gatgcagaaa caaaacgatt agacaatgga
     1381 ataacttcag tgacttggga agatatccaa cagtatgatg atagtggaaa cgaatatacg
     1441 tttaaagtgc aagaagtaga tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa
     1501 attgaaaacg ggctagtcgt tacaaatgag aataaagaag tcatttcagt ctcaggacaa
     1561 aaaacatggg aagacaatga gaaccaagac ggcaaacgac cgacgacgat cacagtaaat
     1621 ctattagccg acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc
     1681 tatcgtttca caaatctgcc aaaatacaga gacgggcaag aaatcatcta tactgtaacg
     1741 gaagacaacg tgcccgaata cagtacgacg attgacgggt ataacatcaa aaacagttat
     1801 acaccggaaa aaacaaatat atctatacca ggtagccata taacaccgtg gaaaaatttt
     1861 ccagagaaga cagagagaga gaaaattaga aatctattct ctcaaaaatt gcaaatattt
     1921 gctcatacag gagaatccag cgaacaaaga agcaattata ttagtaagag agctgtacct
     1981 aaacagataa caaataaatc aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt
     2041 tttgctgtaa tcattggttt attgatagta actatctgtg ctgggatatt cttacaaaaa
     2101 tataaaaaag tttagttaga atataatatt ttttgttaaa tatgactgaa atcaaaagaa
     2161 taaaattccg atttataatc gaaaaaagaa gcatttttat atatgcttct tttttcgtag
     2221 aatcaataaa tatggatttg gctaactatg gaagaatact cgtattagtt ttcagcgttc
     2281 atactagttg ttacattgtt tgattggcca aaagaatttc tgatatattt tgtgctaaat
     2341 aaagaaaaag acgcttgaat tgggaaataa gaaaactact ctatcattac aaattttcat
     2401 aaactggcag atgttctaag taaacaagta tcttttcaaa gtcggaaaaa tccataatca
     2461 acgtagtggt attgatattt ggatgaaagc ctacggtatc ttgacgatca atagcagcat
     2521 cgatcacgac ttggattttt ttctctttgt cgtgcatcaa tgctaatgga gtcactgtac
     2581 ctgctggaac gcctaggagg tcaggaagct gttcttcaga aacaaaagat aagcgctttt
     2641 cttttaattg ttcagctagt tgttttaaat cggcgtgctt ttcatcaggc aagatgacaa
     2701 gatagatttg ttttcctttt cttgatttca ataatagatt ttttacttgc ggaccaggta
     2761 gggaaaaagg gacatttttg actgacgtaa tcgcaggatg atcgactttt tgaaaagaga
     2821 tacccagttt ttttagtagt tcataagctt cttgttcggt tgcacgactc atcgcgcatc
     2881 accctccttt ttttattagt gtatcataaa aaagagttga caaatgaaaa ataatcatgt
     2941 aaattacacg taaagttaaa acaaatgaca tcgaaaagaa gagtagccgt taggtgtttt
     3001 tagagagtct ctggttggtg gaaagaggca gcagttaacc gtgaaacaca tcttggagtc
     3061 gattttctga agcgtatagt aggaaaatcc ggggagcccg ttacagctgc ggtcgttgct
     3121 agatgaccag ataaggctgg cttttccgtg aggagtcggt aaaaaaaggt ggaaccacgt
     3181 gattaacgtc ctttgatctt cggatcaaag gactttttgt tttcatctga acggcaacga
     3241 ctgtgtgagg ttttttctgc aaggaaaaaa taaacagagg tggaaccacg tataatacgt
     3301 cctcttggca tttgccaaga ggattttttt attttaaagg aggaaaagaa gatggagtat
     3361 ttgattgaag ttatgccgca attattagta ggagcactca caacattgaa attattttta
     3421 tttaccttga ttggctcatt accattaggg attgttttag cattaggatt gtctttgcat
     3481 tttaagccgc tacgctactt gcttcaaaca tatgtatggg ttatgcgggg aacaccgctg
     3541 ttgttgcaac tgatttttat tttttatggg ttgccgacga ttgggatcgt ttttgatcgt
     3601 ttcgaagcag cactcattgc ctttatctta aactatgcag cttattttgc agagatcttt
     3661 cgtggaggga tacaatcgat tcctcaaggt caatatgaag cagcgcaagt tttgcaatta
     3721 agtccctttc aaacggtgac gaaaatcgtc atcccacaag tgacaaagat tgttttacct
     3781 tctgtaggga atgaagttat caacttggtc aaagattctt ccttgatcta tatattaggt
     3841 ttaggtgacg taatgcgtgc tgggaaaatc gcgatggaac gcgacgcgac tttactgcct
     3901 ttgctaggcg tggcaatcat ctatcttaca ttgactggta ttctaacaat cgtaatgaaa
     3961 caagttgaag gaaaattaaa ttattaccgc taactgatag gaggaagaaa tatgattgaa
     4021 ttgaagaaag tgaacaaagc atttggtgaa aaaaaaataa tcaaagattt gaatctaatc
     4081 attccagatg ggaaaacatt agctatcgta ggtccttccg gtggcggtaa aaccacgctt
     4141 ttacgtatct tggctggctt agaaagttct gacagcggag aattttattt agacggtgta
     4201 ccgttcaacc cattcgagct taaaatgaaa gaacaagttg taggagtcgt attccaagac
     4261 ttccagctat ttccacatct gaatattttt gaaaacatta ccttagcacc aaaaatggta
     4321 ttgaaacaga caaaagaaga atacaccaaa aaagcagaag aattagcggc ttcattaggg
     4381 attagtgatt tattgaatat ctatccttat cagctttctg gcggacaaaa acagcgggta
     4441 gcgattgcca gagcattggc tatgaatcca cgggtattgg cttatgatga accaacaagt
     4501 gctttagatc ctgaattacg ccagcaagtc gagcgtttga tcctatcatt gaaagaagat
     4561 ggggtaaccc aaattattgt cacccatgat ttagtatttg cagaaaatgt cggtgatcaa
     4621 ttactaaaag tttccccaat tcattaagaa aggagaagat agagatgaaa aaaaccagtt
     4681 ttctattcgc tttgatcgca ggtcttcttc tttttgcagg ctgttcgaac aaaaaaactt
     4741 cagcagataa ttgggcgact atcaacgaag agaaaaaaat cgttataggt ttagacgata
     4801 catttgttcc tatgggattt agagataaag acgggaagct cacaggattt gatattgatt
     4861 tagccaaagc agtctttgaa caatatggga ttacggtaga ctttcagccc attgactggt
     4921 caatgaagga atttgaactg aacaatggaa cgatcgattt gatatggaac ggctattcca
     4981 aaacgccggc aagagaaaag aaagtgcaat ttacaaaacc ttatatggaa aacgatcaag
     5041 tgctgatcac acctaaagaa tcaggaatca caaactttgg acaaatgaat aataagagat
     5101 taggtgcgca aaatgggtca tctggttatg atgtatttac gaaacaacca gaagtattaa
     5161 aagagatagt caaaaaccaa gatgctgttt tgtatgatag ttttaatgaa gcattgatcg
     5221 atctgaaaag cagacgggtc gatggtctgc tgatggataa agtatacgca gactattatt
     5281 tgaaacaaag aaacgaacta gaagacttca acataacaaa aggttcttat gagagtgagg
     5341 attttgcagt tggtgcacgc aagtcagata gtacattagt gaaaaaaatc aatgaagccc
     5401 tagatcaact agagaaaaca ggtgaattcc aaaaaatatc cgataaatgg tttggcgaag
     5461 atgttacgcc gagaaattaa caaatagggg actgtgacaa aagacgtgtc acagtccctt
     5521 tttccgaata aacagtgttc tcctgccaac tccttgtgac tcggagctga atggcaggct
     5581 cacaacctct tggtaaacgg tgttcaaaag ccagtttttc ggtattaagc caaatttatg
     5641 caaaaatgta gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt
     5701 ttcacaacct cctttacata attttatttt gttgtggaag gggtttcgtg ttattctaaa
     5761 agaggaacga ttgaaggtta taggaaagga agagatgaat ggaacacaaa gaacttacct
     5821 catttccaaa agattttctg tggggctctg cttctgcagc gtatcaagta gaaggagctt
     5881 ggcaagaaga tgggaaagga gaatcagtct gggatcgatt tgtacggata cctggaaaga
     5941 catttaaagg aacgaacggt gatttggcag tagaccacta tcatcgttat aaagaagata
     6001 ttgctttaat gaaagaacaa ggtctgaaag cttaccgctt ctctgtagct tggacacgga
     6061 tttttcctaa tggacgagga gaagtcaatc aagctgggct cgctttttat gagagattga
     6121 tcgacgaatt gattgaaaac gatattgaac ctatgttgac tttatatcat tgggatcttc
     6181 cacaagcatt gcaagatgaa tataatggtt gggaatcacg tcagatcatt gaagatttca
     6241 ctcattatgc agaaacatta tttgaggcat tccgcgggaa agtccattac tggattagtt
     6301 tgaatgaaca aaatatcttc acttcattag gttatttgtt agcagcacat ccgccaggtg
     6361 tgacagaccc gaaacgaatg tatgaagtta accatattgc taatttagca aatgcatctg
     6421 tcatcaataa atttcacgag ttagaaatgc ctggaaaaat cggaccaagc tttgcgtata
     6481 cgccaaatta tccaattgac agtaatcctg aaaatgttct ggctgctgaa aatgcagaag
     6541 acctgatggc caattattgg atggatgtct atatgtgggg aaaatatccg attgctgcca
     6601 tgaggttctt agaagaaaaa ggatgggcac caacgattga agctggcgat gcagaattgc
     6661 tagaatctgc taaaccagat tttcttggga tcaattacta tcaaacggcg acgaatgcat
     6721 tcaatccatt aaacggagtt ggtgctggaa aaatgaatac gacaggaaaa aaaagttcat
     6781 cagaagaaac tggagttcct ggaatgtata aaaaagttga gaatccattt gtcgaacgaa
     6841 caaattggga ctgggagatt gacccagaag gattaaggat cggactgcgt cgtatcacaa
     6901 gccgttaccg catgccggta ctgattacgg aaaatggctt aggagagtat gacaagttga
     6961 cagaagataa acaaatccat gacgactatc gaatcaatta cttacaaagc cacgtcaaag
     7021 ccatcaaaga agcaatttcg gatggagcag aagtcctagg ctattgcacc tggtcttata
     7081 cagatttgct tagctggctg aacggttatc aaaagcgata tggatttgta tatgttgatc
     7141 aagacgaaac acaagaagga tctttggaac gatataagaa agacagttat tactggtacc
     7201 aaaaactgat tgaagaaaat ggagagaacc tttagttcac atacttaaaa caagaaggta
     7261 cggctggata tggccgtgcc ttttcttgat aaaatcattt agaaattaag aaaaactgta
     7321 aaataagctg aaaaatgaaa gaaagcgtca gttctttcaa acaaaacttt agttccctta
     7381 cttttttttg tataatgaaa cttgatgaaa tgagggataa taaatggcac aaaagaaacg
     7441 gcctactaaa aaaaggaaaa agacgaaaaa aacgaaaaag caaaaacagc agcaggaaca
     7501 aatgctgacg attggtgttg ggtttgcctt gattttattt gctgtcttcg gctttttaaa
     7561 attaggtttt ttaggaatat tgattgcaaa cggctttcgg atcattgcag gaaatactta
     7621 ccaaatcctc tgtcttttat tagccgtatt aggattttgg attgtcatta agaatacaga
     7681 gttttcaatt ggtaaaaacc gacgctggtt tggcggcata ctcttttatt tcggtatctt
     7741 attattgtta catgcccatt tatttggcaa actccatact ggggaaccaa atatcatggg
     7801 gacgacatgg gatttgttag ccagtgatat aaaacaaagt caagtagaca ataacgttgg
     7861 tggtgggatg attggagcaa tcctttatca ttttacttac ttcttgattg cacagcctgg
     7921 aagttattta gcagcagtgc tattactggc aggaggagca ttcctgttca gtaatctgga
     7981 aggctatcag ctgttaaatg gtatccaatc aattggagaa cgagtacagg aattattgga
     8041 aggtgatcct gccaagcaag ctcgaaagca agcggcaaag gaagagagaa tgaaacagcg
     8101 cgcagaagcg aaagaagcaa ggcgcttagc tgcaaaagaa gctgcagaat atgagaagaa
     8161 aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac cagaaaatac
     8221 agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata tccatcctgc
     8281 gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag aaggtttttc
     8341 agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag cagaacagga
     8401 aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa ctgtggatca
     8461 aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa ctttccaaag
     8521 tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca caaaattcga
     8581 agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag atgatatcgc
     8641 gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta aatcactgat
     8701 tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa tcatcgaagc
     8761 acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg tttctggacg
     8821 ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt cgactggtag
     8881 tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg ctaagcccca
     8941 tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt acaacggcat
     9001 acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag ccttacaaaa
     9061 agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag taagaaatat
     9121 ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga aacatccaac
     9181 cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg tagccagcaa
     9241 tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg ggattcatat
     9301 gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca aagcaaatgt
     9361 accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga tcattgattc
     9421 taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa tgggtgagaa
     9481 taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac gggtcgttca
     9541 atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga cagatgaagt
     9601 tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag caaaagcact
     9661 tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc ggatcggtta
     9721 caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg gcccgtcaga
     9781 aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa cgttgccgga
     9841 cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac caataaaaag
     9901 acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct aatacggtat
     9961 gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat ttgtgaagta
    10021 ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa aagagggaaa
    10081 atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc aattggttta
    10141 tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg tatcaaaaac
    10201 gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa aaattatcgg
    10261 agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg gatggtacag
    10321 taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg atgagacaag
    10381 aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc tgtacgtttt
    10441 gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt gttgcacaga
    10501 tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg
    10561 ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac tttttgcata
    10621 tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt tccactagtg
    10681 gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat ctggctattt
    10741 ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc
    10801 caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac cgtcgaatca
    10861 cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg caacaattag
    10921 cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca tataatccag
    10981 tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga ttttatgatg
    11041 tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca gatattgatg
    11101 cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc
    11161 ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga actgttcaac
    11221 ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac aagaaaaacc
    11281 ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg ggttttagca
    11341 attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg ataagtttct
    11401 acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac atgtttaata
    11461 tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac attgagattc
    11521 atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat tttatcaaac
    11581 aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac agatgctccg
    11641 tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga gtgtgccata
    11701 gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac aatgatatcc
    11761 gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt caatgcttgc
    11821 gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc taatctatcc
    11881 gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt ggataaagca
    11941 tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc tgtatcaatg
    12001 aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta
    12061 tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg aaaggtgaag
    12121 actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg gccaccaccg
    12181 actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg ttcaatattt
    12241 ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa
    12301 gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat cagcactact
    12361 tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt tccaatggta
    12421 taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg ttgaaacggg
    12481 ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga ggtgaaccta
    12541 agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa taagtatcct
    12601 aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt tcctcttagt
    12661 atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa attaagatta
    12721 ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa gcaaaagata
    12781 atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt cctgatcttt
    12841 cctattttga ataaagtgtt tctgtataat tttttatttt ataagtaaga taaataatga
    12901 aagaatagag atactgattg gtagctaaag atttttgagc gagaacattt cgttttttca
    12961 aaaggactgt tagaataagc aagaacaagg gggaagacgt atgataatca gtgaatttga
    13021 ccgtaataat ccagtattga aagatcagct ttctgattta ctgagactga cttggccgga
    13081 agaatatgga gacagctcgg cagaagaagt agaagaaatg atgaatccag aacgaatcgc
    13141 ggtagcagcg gtagaccaag atgagttagt aggatttatt ggtgcaatcc ctcaatacgg
    13201 tatcacaggt tgggaattgc atccattagt tgtagaaagc tcccgacgaa agaaccaaat
    13261 aggtactcga ttagtcaatt acttagaaaa agaagtagct tccagaggag gaatcacgat
    13321 ttatttaggt acggatgatt tagaccatgg aacaacgtta agtcaaacgg acctgtatga
    13381 gcatacattt gataaagtgg cttccatcca gaaccttcgt gaacatccgt atgaattcta
    13441 tgaaaaatta ggttataaaa tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc
    13501 ggatatttgg atggcaaaaa cgattattcc tcgaccaaat tctcaataat aaaaagaggt
    13561 tgtgacagaa gtaatcagct tcaagaaata agaaggaatt tacgaaaatt acttcttgaa
    13621 tttttgtgaa attccaactt atttccgaag aagctacttt tggaacaccg tgtaccagag
    13681 gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat tttgtgaaaa tggctttcta
    13741 catttttgca taaatttggc tt
//
LOCUS       DACCVH010000070        13732 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.070, whole genome shotgun sequence.
ACCESSION   DACCVH010000070 DACCVH010000000
VERSION     DACCVH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.070"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(143..1345)
                     /locus_tag="IVV98_002154"
     CDS             complement(143..1345)
                     /locus_tag="IVV98_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7807783.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="IVV98_002155"
     CDS             complement(1348..1542)
                     /locus_tag="IVV98_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP7807784.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="IVV98_002156"
     CDS             complement(1589..2437)
                     /locus_tag="IVV98_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAP7807785.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="IVV98_002157"
     CDS             complement(2642..2992)
                     /locus_tag="IVV98_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807786.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="IVV98_002158"
     CDS             3587..4033
                     /locus_tag="IVV98_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP7807787.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="IVV98_002159"
     CDS             4657..5649
                     /locus_tag="IVV98_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7807788.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="IVV98_002160"
     CDS             5665..6549
                     /locus_tag="IVV98_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807789.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="IVV98_002161"
     CDS             6598..8205
                     /locus_tag="IVV98_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7807790.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="IVV98_002162"
     CDS             8206..9690
                     /locus_tag="IVV98_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP7807791.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="IVV98_002163"
     CDS             9867..10859
                     /locus_tag="IVV98_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7807792.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="IVV98_002164"
     CDS             10911..11780
                     /locus_tag="IVV98_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7807793.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="IVV98_002165"
     CDS             complement(12200..13693)
                     /gene="guaA"
                     /locus_tag="IVV98_002165"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP7807794.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4214 a         2321 c         2832 g         4365 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattattg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tt
//
LOCUS       DACCVH010000071        13622 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.071, whole genome shotgun sequence.
ACCESSION   DACCVH010000071 DACCVH010000000
VERSION     DACCVH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.071"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            24..266
                     /gene="yaaA"
                     /locus_tag="IVV98_002166"
     CDS             24..266
                     /gene="yaaA"
                     /locus_tag="IVV98_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP7807795.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            253..1377
                     /gene="recF"
                     /locus_tag="IVV98_002167"
     CDS             253..1377
                     /gene="recF"
                     /locus_tag="IVV98_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP7807796.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1374..3320
                     /gene="gyrB"
                     /locus_tag="IVV98_002168"
     CDS             1374..3320
                     /gene="gyrB"
                     /locus_tag="IVV98_002168"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP7807797.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3340..5811
                     /gene="gyrA"
                     /locus_tag="IVV98_002169"
     CDS             3340..5811
                     /gene="gyrA"
                     /locus_tag="IVV98_002169"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP7807798.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6047..6346
                     /locus_tag="IVV98_002170"
     CDS             6047..6346
                     /locus_tag="IVV98_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP7807799.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6396..6908
                     /gene="ssb"
                     /locus_tag="IVV98_002171"
     CDS             6396..6908
                     /gene="ssb"
                     /locus_tag="IVV98_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP7807800.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6934..7170
                     /gene="rpsR"
                     /locus_tag="IVV98_002172"
     CDS             6934..7170
                     /gene="rpsR"
                     /locus_tag="IVV98_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP7807801.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7313..9286
                     /locus_tag="IVV98_002173"
     CDS             7313..9286
                     /locus_tag="IVV98_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP7807802.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9292..9744
                     /gene="rplI"
                     /locus_tag="IVV98_002174"
     CDS             9292..9744
                     /gene="rplI"
                     /locus_tag="IVV98_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP7807803.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10018..11385
                     /gene="dnaB"
                     /locus_tag="IVV98_002175"
     CDS             10018..11385
                     /gene="dnaB"
                     /locus_tag="IVV98_002175"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP7807804.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12165..13457
                     /locus_tag="IVV98_002176"
     CDS             12165..13457
                     /locus_tag="IVV98_002176"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP7807805.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4539 a         2466 c         3003 g         3614 t
ORIGIN      
        1 ataatgaaaa tgagggatgg gcattgaaac aacaagtcat tctaaatacg gaattcatga
       61 cgttgggcca aatgttgaaa gaagtcacag ttatcggtag tggcggacaa gcaaaatggt
      121 atttggcaga aaacactgtg ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac
      181 tttatcccgg catgatggtt gaagttccag aagtaggaac tttttttatg gtaaaaaaag
      241 gaaacgacga taatgaggct gaataagctg tatttaaaaa attatcgaaa ttacgaagag
      301 ctgaacatcg aattttccaa gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa
      361 acgaatcttt tggaaagtat ctacgtatta gctatgacgc gaagtcatcg gacaagtagt
      421 gagcaggaat tgattggctg gactgacgat caggcgatga ttcaaggaga gatcacaaaa
      481 ggttcatcca ctcttccatt agaaatctta ttatctaaaa aaggccgaaa aaccaagatc
      541 aaccatatcg aacagaaaaa gttaagtact tacgtgggac aaatgaatgt cattttattt
      601 gcaccagaag atctttcttt agtaaaaggc agcccgcaga tcaggcggaa gtttttagat
      661 atggaattag gccagatcaa tccaatctat ctttatgatc ttgtccaata ccaagcaatt
      721 ttgaaacaaa gaaaccagta cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt
      781 tatttggata ttttgtccga acaactagca gcgtttggca gcaaagtatt gaaagcaaga
      841 gcacagttcg tcaagcgatt ggagttttgg gctaattctt tgcatcagca aatcacccat
      901 caaaaagagc agctggaaat cgagtatctc accgcagtcg attctttaga aacacatacg
      961 caagagcaaa tccaagaaca atttctcgca cttttgaacc aaaataaaaa gaaagacctt
     1021 tttcggggaa caacgacagt tggtcctcat cgtgacgatc tttccttttt tattaatcag
     1081 aaaaatgtgc agacttatgg atcgcaagga cagcaaagaa caactgcact aagtgtcaaa
     1141 ttagcagaaa tcgatttgat taaagaagag acaggggaat atccaatcct tttgttagat
     1201 gatgtgatga gcgagctgga tgataatcgt caactccatc tgctagaaac aatcgaagga
     1261 aaagttcaaa cgttcttaac aacaacgaca cttgaccatg taaaaaataa aatgactgtt
     1321 gaacctgaga ttttttatgt tcaacaaggg aaactaaaag gagaagaaac tgaatgacag
     1381 aagaaagaag tttagtagaa cgcgctaaag agtatgatgc cagtcagatt caagtacttg
     1441 aaggacttga agccgttcgt aaacgacctg gcatgtatat cggttcgact agttctgagg
     1501 gtctgcatca ccttgtttgg gaaattgtcg ataattcgat cgatgaagta ttagcaggtt
     1561 ttgcaacgaa aatccatgtg attattgaaa aagacaacag tatcaccgtt attgacgacg
     1621 gtcgggggat acctgtagat atccaggcaa aaactggacg tcctgcagtt gaaacggtct
     1681 ttactgtttt acatgctgga ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac
     1741 ttcacggagt aggatcttct gttgtaaacg cgctttctac acagcttgat gtcaaagtat
     1801 acaaagaagg aaatgtgtac tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa
     1861 agattatcga acaaacggat cgccatggaa caacggttca ctttacgcca gaccctgaaa
     1921 tttttacaga gacaactgag tttgattttt caaaattggc tacccggatc cgtgaacttg
     1981 ctttcttgaa ccgcgggatg cgtatatcga ttgaagacaa acgagaagaa gaaccagtca
     2041 tcaatgaata ccattatgac ggcgggatca aaagttatgt cgaatacttg aatgcaaaca
     2101 aaaccgtgat ttttccagaa cctgtatatt tggaaggtga acagcaagat atcgcagttg
     2161 aagtctctat gcaatataca gacggctacc attccaatat catgagtttt gccaacaata
     2221 tccatacgta tgaaggtgga acacatgaat caggattcaa gactgcttta actcgtgtga
     2281 taaatgatta tgcccgaaaa caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg
     2341 aagacgtgcg agaaggattg acagctgtta tttctatcaa gcatcctgac cctcaattcg
     2401 aaggacaaac aaaaacaaaa ttgggcaatt ccgaagtacg gacagtcact gatcggttat
     2461 ttagcgaaca tttcatgaaa ttcttgctgg aaaacccaag tgtgggccgg caaattgttg
     2521 aaaaaggatt actagcttcc agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga
     2581 gacgtaaagg tgctttagag attagtaatc tgccaggaaa attagcggac tgctctagca
     2641 acgatcctga aaaatgcgaa ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta
     2701 agcaaggtcg taatcgagag tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg
     2761 ttgaaaaagc aagcatggac aagatcttgg caaatgaaga gatccggtct ttatttactg
     2821 ctatgggtac agggtttgga gaagattttg atgtatcgaa agctcgctac cacaaattag
     2881 ttatcatgac tgatgccgat gtcgacggcg cgcatatccg tacattgctg ctgactcttt
     2941 tttatcgtta catgcgtcct attgttgaag ctggatacgt ctatattgct cagccacctt
     3001 tatacggggt aaaacaaggg aagaatatta cgtatgtaca accaggaaaa aatgcagaag
     3061 aagagttgaa acaagtcgtt gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt
     3121 ataaaggact tggagaaatg gatgatcatc aactatggga aacaactatg gacccaagca
     3181 atcggatgat ggcccgcgtc agtgtggacg atgctattgc agcagatcag atatttgaaa
     3241 tgttgatggg ggatcgagta gaaccccgtc gtgcattcat cgaggaaaat gcacactatg
     3301 tgaagaactt agatatttaa tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa
     3361 aacatccatg atgtcaatct aaccagcgaa atgaaagact ccttcatcga ttatgcgatg
     3421 agtgttattg tcgcacgtgc acttcctgat gtcagagatg gtctgaaacc cgttcatcgc
     3481 cgtattttat acggcatgaa cgaattaggt gtaacaccgg ataaagccca taaaaaatct
     3541 gccagaatcg tcggagatgt catgggtaaa taccatcctc atggagacat tgcgatctat
     3601 gagtcaatgg tacggatggc acagccattc agctaccgtt atatgctagt ggatggtcat
     3661 ggaaactttg gttctgttga cggtgacggt gccgccgcta tgcgttatac cgaagcacgg
     3721 atgagcaaaa tcgctacaga aatgctgcgt gatatcaata agaacactgt tgatttccaa
     3781 agcaactatg atgatacaga aaaagaacca gttgtactac ctgctcgctt cccgaatctt
     3841 ttagtgaacg gaacaacggg gatcgccgta ggtatggcca cgaatatccc acctcataac
     3901 ttgtctgagg tagtagcggc tatcgatttg ctgatggata atcctgatgt gacgaccaat
     3961 gaattgatgg aagtattacc tggaccagat tttccaacag gtggtttggt tatggggaaa
     4021 tcaggaatcc gaagagcgta tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt
     4081 gagattactg agatgccaaa tggtaaagaa cggatcatcg tgacagaatt gccttatatg
     4141 gtcaataaag caaaattgat cgaacggatt tctgaactgc acagagacaa gcgtatcgaa
     4201 gggatcacag atttgcggga cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc
     4261 cgtcgtgacg ccagcgcatc cgttatcttg aataacttat ataaattgac atccttgcaa
     4321 aattcatttg gattcaatat gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg
     4381 aaacaaatcc ttgaaaacta tatcgaacat caacgcgaag tcatcacacg acggacggtc
     4441 tttgaaaaag aaaaagcaga agcaagagca cacatcttag aaggtttgcg tattgctttg
     4501 gatcatatcg atgaaatcat tgcgattatc cgcgggtcta aatcagatga cgaggcaaaa
     4561 gcaacaatga tcgaacggtt cgatttatcc gatcgccagt ctcaagctat tttagatatg
     4621 cgtttacgcc gattgaccgg tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc
     4681 ttaaaactga ttgaagattt aactgacatt ctggcaagac cagaacgtgt tacagaaatc
     4741 atcaagaatg aattagcaga cttgaatcaa cgatttggtg ataaacgacg cacagaatta
     4801 ctagtcggtg aggtcttaag tctggaagat gaagatttaa tcgaagaaga agaaatcgtt
     4861 attacattga caaacaatgg ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa
     4921 cgaaggggtg gacgtggtgt ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat
     4981 ctggtttctt gttctaccca tgatacattg ttattcttta cgaataacgg aaaagtgtat
     5041 cgggcaaaag gatacgaaat tccagaatac gggcgtacag ccaaaggaat cccaatcatc
     5101 aatttactag gtatcgattc gagtgaaagc atccaggcaa tcattgcggt gacgggagaa
     5161 gcagaagaag gccactatct cttctttacg acgcgtcaag gtacagtaaa acgtacttct
     5221 gtcactgctt ttgctaacat ccgaagtaat ggtctgatcg caattggttt gaaagaagac
     5281 gatgagctcg tcaatgtgct actgacagat ggtcaatcta atatcattat tggaacacat
     5341 aacggctact ctgtcacttt caaagaagaa gcagtccgcg atatgggacg tacagcttcc
     5401 ggggtcagag ggatacgcct gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag
     5461 gaaaatcaag aagtattagt gatcacagaa aaaggttacg gaaaacggac aaaagtatcg
     5521 gaatatccag tgaaaggccg cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa
     5581 aatggtccac tagctggatt gaccactgtt tctggagatg aagacatcat gctgattaca
     5641 gataaaggtg tcattatccg tttcaacgta tcgactgttt ctcaaactgg acgttcaaca
     5701 ttaggcgtac gtttgatgaa gatggaagct gatacgaaag ttgtcacgat ggcagcagtc
     5761 gaaccagaag ctgcagaaca aacagttgaa gaacaaggat cagaagaata accatcaaga
     5821 ctaagtgtgt aagctagcaa gaataaccga ttaaaaaatc tggttattcc tgctggcttt
     5881 tttgattagt tgaatttctc ttaaaatatt cgaaactgtt cattctgtat tgcttttgac
     5941 caaaatagag tgtataatta gagcttgtga gtagtctaat taattagata actctccttg
     6001 ctcttaggaa cctaagagcc gaaagtccac agggaggtga atatcaatgg aaaacacgaa
     6061 atatgaaatc atgtacatta ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat
     6121 cgaacgtttc gatgcaatct tgaaagataa cggagcagaa gttatcgaat caaaagattg
     6181 ggaaaaacgc cgtttcgctt atgaaatgaa cggttaccgt gaaggtatct atcacatcgt
     6241 taaagtatct tctccatcat cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat
     6301 caacgacgat atcattcgtc acatgattgt taaagaagaa gcttaattgt tgtttcatgt
     6361 gaaacaatag aaaacgatga gaggagatga ctattttgat taataatgtt gtattagttg
     6421 gacgtctgac gaaagatcca gatttgcgtt acacagcaag tggtacggca gtcgcaacat
     6481 ttactttggc tgtgaatcgt aattttacaa accaaagcgg caatcgcgag gctgatttta
     6541 tcaactgtgt gatttggcgc aaatcagcag aaactttagc aaactatgct cgtaaaggaa
     6601 cacttttagg tgttactgga cgtatccaaa ctcgttctta tgataatcag caaggacaac
     6661 gtgtatacgt gacagaagta gtagctgaca acttccaatt gctggaaagt cgttctgcat
     6721 ctgaaaatcg ccaacaaagc ggcggattcc aaagttctgg tcaatcagct ggcggatttg
     6781 gcggaaacaa taactctaat caaacatctc aatcatccaa cggtatgcct gatttcgacc
     6841 gtgatacttc tgacccattc ggctcaagtt caacgatcga catttcagac gatgatttac
     6901 cattctaaac gaatttgata ggagggaaat agaatggcac aacaaagaag aggcggacgt
     6961 aaacgtcgta aagtagacta cattgctgct aaccatattg aatatatcga ttataaagat
     7021 atcgaattac taaaaagatt tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact
     7081 ggtacaggcg ctaaaaacca acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg
     7141 ggcttgctac ctttcgttag cgaagactaa taaatcctag gaattgaatg actgatcctt
     7201 ttgatcagct attcaattcc tttttttctg taaaaataac ctctattcgt ttagtcgctc
     7261 gaatgacgaa agttatggta aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa
     7321 taaaaacaat catttatccc cgaaacctct cttccttatc ctgtttatat taatcgaagt
     7381 attggtagtc ttaattttac catttcgttt tgttagcgct tcggtcattc tattgatgaa
     7441 tttatggggt gttcgctatt ggttgaaaat gaaacgttgg cttattttaa ataaacgtga
     7501 aaaaatccag caggcttcga ctgtagctga aaccaatcta gcttatgtct cagaagtcat
     7561 gcctgtagga gtgattgctt atcagccatc aagccaaaaa atcgaatggc tcaatccatt
     7621 agcattgaaa atcaaagatc aaagtggatt aacagaggaa gaattgctag atactttttt
     7681 tactgcaaaa gaaaaaaaga aaaaccaagt ctatctagca gataaaacat ttcagtttga
     7741 tatggataca gtaaagggtg ttgtttattt taatgatatt acccaaaacc agttgttaaa
     7801 actccatcag acgaacagtc agccggtgat tggtatttta tctattgata actatgcaga
     7861 tgccattgat aaattagatg acaaagagat ttcttatttg aactctttcg tcactacact
     7921 agtttctgac tggatgaatg aataccatgt ctttttcaaa agaatcaacg cagaacggtt
     7981 tttcttcgta gcacagatga tcgatctgaa aaagatgatg gataaaaaat ttgatttgct
     8041 ggatcgcttt cgagcagaag ctgaaaaaca gagctcgcct atcaccctta gtatggggat
     8101 tgcttatggc tcaagaaccc tcgatgaaat cggtggagaa gctcagaata atttagatgt
     8161 tgctttagtc cgtggaggcg accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc
     8221 tgtttattat ggggggaaat ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc
     8281 gatgagtacc gctttgcgtc ggatttttga tgaaacaggc gatgtgttta tcatggggca
     8341 caagtttccg gatatggatg ctttaggctc tgcttttggt gtcagttgtc tggcacgctt
     8401 caaccagaaa aaagcttaca tcgttatcaa tgagaacgag atcattccag atgtagaacg
     8461 gtgtcttgaa gaaatccata agcatcctga attagaaatg caactaatct ctccagaacg
     8521 tgccatagag ctgaaaaaag aagaggacct cctcgtgatg gtggattacc ataaaccttc
     8581 tctatcgatc tctcagggcc tatatgagca atttgataag attgtgatca ttgatcacca
     8641 tcgtcgtggg gaagagtttc caagtaaacc tctgctgact tatattgaat cttcagcttc
     8701 ttcagcttca gagctagttt ctgagctgat ccaataccaa agcagcaaaa caaatcgctt
     8761 agatcgtttt gaggccacat tattgcttgc agggatggtt gtagatacaa atagtttcaa
     8821 tgtccgtaca actgcacgaa cttttgacgt tgccagctat ttaaggtctt gtggagcaga
     8881 cgcatcctta gtacaatatt tattgagctc ggatttagcg acatacttgg agatcagcaa
     8941 tttgattgct ggaagcgact atgtgacttc tgatattgtt gtggcggcag ggacagacga
     9001 aaaagagtat aatagtgtta tagcagcaaa aacagcagat acattgcttt cgatgatcaa
     9061 tatcaatgca gctttcgtca ttacaaagcg gacagacggc ttgattggga tcagtgccag
     9121 aagtaccggc acgatcaacg tccaaatcat catggaatcc ttaggtggcg gaggacactt
     9181 cacaaacgca gctactcaac tggaaaatac gacagttgag gaaacaaaac agaagctatt
     9241 tgctgcaatc aaagaaaata tgaatcaaat atatgataag gagtaatcca aatgaaagta
     9301 atttttttac aagatgtaaa aggaaaaggt aaaaaagggg acatcaaaga agttccagca
     9361 ggttatgcac aaaattatct aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt
     9421 atcagtcagt tagcaggaca aaagaaagca caagaaaaac acgaagctga aatcttggaa
     9481 gaagctaaaa agttaaaaga attcttggaa aaagaagata ctgtagtcga attgaaggcg
     9541 aaagcagggg aagacagccg tttgtttggt tcgatccctt caaaacaaat tgctgaaggg
     9601 ttaaacaaac aatacaaaat caaattagat aaacgaaaaa tcgaattaga aaatccgatc
     9661 cgttcactag gctacacaaa cgtacctgtt aagcttcatc atgaggtgac ggctacgatc
     9721 aaagttcatg tcgtacaaga ataacaaatc ttgatagcga tgttcagctg gtaagtataa
     9781 ccagaaggaa aaaagacaaa ccgaaattta tctgagaaaa cagctgcagc aatgaaagca
     9841 aaagctgcaa atcgatttca gattgatttc ggtttctttt ttgggaacag caaaatagca
     9901 taaagaaaac gagtataata aaagagaact atttttttat tacactttcg gtacgaatga
     9961 tgacttttct ctcattttct tgtaaaatga agcaattgaa gacaaggagc gatacgtatg
    10021 aatgaagtgt ggcaggatcg aatcccaccg caaaatattg aagctgaaca agcggtttta
    10081 ggctctgttt ttcttgacgc agaaacgatc attgatgcca tggagtacat agagccaaaa
    10141 gacttttatc gtcgtggcca tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt
    10201 aatgaagcga ttgacgtggt tactgtcaaa gaccggctgg aacaagccaa tttgttagaa
    10261 gatgccggtg gtttaagtta tctctcagac ttggcattag cagttccgac agcagcaaat
    10321 atcgtctact atgcgaaaat cgttgaagaa aaatcattgc tgcgtacatt gatccagaca
    10381 gcaacaggaa tcgttacgaa aggattcgag caaggagaag aagttcaaac aattttagat
    10441 gatgccgaac gcagtatctt ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct
    10501 attgctgaag tactgaactc cacgattgaa aatatcgatc gactagctca aaacaatgaa
    10561 gaaatcacag gtctaccaac tggctatcaa ggtctggata aaatgacagc aggtttccag
    10621 cccgaagaac taatcattct tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg
    10681 aatattgctc aaaatgtagg aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa
    10741 atgggggcag aatctcttgt aaatcggatg ctttgtgcag aaggttcgat tgaggccagc
    10801 catttacgta caggtcagct ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg
    10861 agtctttctc gagcaaatat ttttatcgat gatacaccag ggatcaaaat ctctgaaatc
    10921 cgtgcgaaat gtcggaaact agcgcaagaa aaaggcaatc taggcttgat attgatcgat
    10981 tatttgcagt tgattgaagg taacggtaaa gagaaccgtc aacaagaagt atcagatatc
    11041 tctcgccaac tgaaaaaact ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag
    11101 ttatctcgtg gagtagaaca gcgacaagac aaacgaccag tgctaagtga tattcgtgaa
    11161 tccggatcaa ttgaacaaga tgcggacatc gtagccttct tgtatcgaga tgattattat
    11221 gaaagagaag gcggagatga cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa
    11281 gtcatcatcg agaagaaccg aagcggtgca cgaggaacag ttgaactact gtttatcaaa
    11341 gaatacaata agttttcgtc gctttcgcca agagaagaat tttaaagaag aggttgtgag
    11401 ccttgagcaa tcccgagagc tctcgtaaga agatgcaagg agtaaccgca ggaacgacta
    11461 gagtacttaa tttaaacaga tctccaaagg gattgtgaca aaagtcttgt cacagtccct
    11521 ttttccgaat aaacggtgtt caatcagctg acccttggta ttagctcagc aaacgtcaaa
    11581 atatgaggaa ctattttgac gtttgtttct ctaatactca ggtcaaaacg ctgatcttac
    11641 gacctctttt ccttaaacgg tgttctcctg ccaactcctc ggtcacaagt cacaatatca
    11701 tcaaacatga gaagcagttt tttgaaattg ctccttgtga ctcagagtta aacggcaggc
    11761 tcacaacctc tttcttaaac ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca
    11821 aacgaaaaat atgagaagct atttttgttt ggctgttctt attacttgat gcaggacagc
    11881 tttttcacaa cctctgattc acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa
    11941 atttcacaaa aatttgagaa gcaattttcg tacattcctt cttatttctt gaagctgacc
    12001 acttctgtta caacctcttt tttaataacc attctaaaaa gataaagttc gttttttaag
    12061 cgtttttata aaataaaaat aaaaatcatt cgattttatt tgaaatatgt atctattatt
    12121 gatacaatgg ttcaggatta aataatatag aacgaggtgt tcacatgtca tctgtagtag
    12181 tagtaggtac gcaatggggc gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa
    12241 atgctgaagt gattgcacgg taccaaggtg gcgacaatgc agggcacaca attaagttta
    12301 acggtgtgac ttataaactg catttgattc cttctgggat tttttataaa gacaagatca
    12361 gtgtgatcgg aaacggcgtt gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt
    12421 tacatgaaaa aggtgtagaa acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct
    12481 tgccttatca tatcaaattg gaccaattac aagaagatgc taagggcgaa aataagattg
    12541 gtacaacgat taaaggaatc ggacctgcct atatggataa agcagctcgt gtaggtatcc
    12601 gtattgcaga cttattagat aaagaaattt ttgaagaacg tcttcgtttg aatctagatg
    12661 acaaaaaccg tcaatttgta aaaatgtttg attcagaacc acttgatttt gacgatattt
    12721 ttgaagaata ttatgaatac ggacaacaaa tcaaacaata cgtcacagat acttccgtta
    12781 tcttgaatga tgctttggat gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa
    12841 tgctggatat cgaccaggga acttatcctt ttgttacttc ttctaaccca gtagccggtg
    12901 gggtaacaat cggaagcggt gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca
    12961 aagcctatac gtcacgtgtc ggtgatggac catttccaac tgaattattt gatgaaacag
    13021 gagaacaaat ccgcgaagta ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg
    13081 taggctggtt tgattctgta gttatgcgcc attctaaacg agtttcaggt attaccaacc
    13141 tatctttaaa ctcgatcgat gtattaagtg gattggaaac agtaaaaatt tgtacggctt
    13201 atgaattaga tggcgaacta atctaccact atccagcaag cttgaaagag ttgaaccgct
    13261 gcaaaccaat ctatgaagaa ttgccaggct ggtcagaaga cattacagga tgcaaaacac
    13321 ttgcagaact gccagaaaac gcacgtaact atgtacgtcg tatctcagag cttgttggtg
    13381 tacgtatctc aacattttct gtcggacctg atagaacaca aacaaacatc ttagaaagcg
    13441 tctgggcgca aatctaagga taaaaacgac gactgaatca ggacgttctt accagagcga
    13501 gtcgaagtgt ttatctatac gataataata acttgaagag gtagtgaaag agacgtttag
    13561 ccttattgcc gataggctgt ctcttgaaca ctgtttattc agaataaggg actgtgacaa
    13621 aa
//
LOCUS       DACCVH010000072        13561 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.072, whole genome shotgun sequence.
ACCESSION   DACCVH010000072 DACCVH010000000
VERSION     DACCVH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.072"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            55..3333
                     /locus_tag="IVV98_002177"
     CDS             55..3333
                     /locus_tag="IVV98_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP7807806.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3874..5781)
                     /locus_tag="IVV98_002178"
     CDS             complement(3874..5781)
                     /locus_tag="IVV98_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP7807807.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5911..6786
                     /locus_tag="IVV98_002179"
     CDS             5911..6786
                     /locus_tag="IVV98_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP7807808.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6866..7840
                     /locus_tag="IVV98_002180"
     CDS             6866..7840
                     /locus_tag="IVV98_002180"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP7807809.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8029..9165
                     /locus_tag="IVV98_002181"
     CDS             8029..9165
                     /locus_tag="IVV98_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7807810.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9302..9646
                     /locus_tag="IVV98_002182"
     CDS             9302..9646
                     /locus_tag="IVV98_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP7807811.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9917..11203
                     /gene="efmA"
                     /locus_tag="IVV98_002183"
     CDS             9917..11203
                     /gene="efmA"
                     /locus_tag="IVV98_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP7807812.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11341..11940)
                     /locus_tag="IVV98_002184"
     CDS             complement(11341..11940)
                     /locus_tag="IVV98_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP7807813.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12344..13465
                     /gene="mnmA"
                     /locus_tag="IVV98_002185"
     CDS             12344..13465
                     /gene="mnmA"
                     /locus_tag="IVV98_002185"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP7807814.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
BASE COUNT         4317 a         2454 c         2894 g         3896 t
ORIGIN      
        1 aattaggtaa tactttaagt aaacgctttc taatttgtta cgggaggaat acacttgtta
       61 aaaaaacgta taaaatacag tgcgctaatg atgaatctcc ttatgctcag taccccggtt
      121 ttaatttctg tcgttgaagt tgctgctaac gaacaacagt ctgtgaacga agaaaatgca
      181 cacgtgaaca ttgaagggat gtcaacaatg gaggaaatac caagaactag tgaagatatg
      241 gatacggaag aaggaaatga tcctatgatg aaagaatcag aaaatgaaaa gacaaaaaag
      301 caatctgaag aagcaaatga agagtggaaa ggggttgttt tcggagaaag cacaagtgct
      361 agtaggtatg ccattgaacc attagaagac ggcgtgcggc tctcttccac gaataacggc
      421 ggaaaattcc agtcaagcgg atcagatgga atgacctatt attatcaagc aatccccaaa
      481 gacatcaact ttaggatgcg ggcgacgatc gaaatagaat cttggaccta tacgaatgcc
      541 caagaaggat ttgctttaat ggtaagagac gcagtaccaa aaaatcattt gtttgggcag
      601 gcattttatt caaattcatt tgccatacta ggcagtcgga tcgaatatgt ctgggactcg
      661 gatagacaag aagtggtcaa cacgagcggc agcaaatata cgatgcgact tggattgggg
      721 acacgggcaa tcacaggaat atcatctgaa gatccgcaag ctgcgccagc tcctgggagt
      781 gtctcagtgg aaacaacacc tttagagact tcagcagggt tcttggaaaa agaaacaggt
      841 tcttataata tattcggaaa cggtcatggg aatctgtttc cggccacgaa ctcgattact
      901 aaactggacg tagagatgaa aaaaacgaat actggtttag aggcatatta ttacgatcct
      961 gaaacaggag aagaaatggc ttctgacatc atgtatgact gggaaaaatt atacgcttca
     1021 gatgaatcgg ttatttatgc aggatttgct gcagcaagga atatgacgat caaggtagaa
     1081 ggaatcgaag ttgcttactc agatcctgcg acagatcctc ctgggcaaga aagacctact
     1141 cgcttgattg atccgattta cactgtgacc tctagtaatc attcaggaaa ccaagatcat
     1201 actatgtcct ttagagcaaa tgctgacgga ttattgacaa ttaaaaataa agcaacagga
     1261 gaggtgctta agaacgcaaa aaacttggct atcactgcga atcgggaatt tgattatcag
     1321 acaaaactga tggaaggaac gaacgaattt actttcagtt ttacgccaga taaaaactat
     1381 ccgccagaag aatacgtaga gatgactagt tatgaaacaa aagagattct tcatacagtg
     1441 gactaccgta aacctaaata ttcgacagtt tatgtaacac cagaagggtc agatgcagga
     1501 aacggaagca gacaaaatcc attatctctg acacaagcat tgagatacgc atatgctggg
     1561 cagacaatcg tcatggcgcc tggaacttat tccttcgaaa gaggattgac gattccaaaa
     1621 ggcgttaacg ggacaagaga aaacccgatt cagttgattg cagagaaaaa tccagaaaac
     1681 aagcgtcctg tacttgattt taaaggaact ggaaatggga tgacactgtt cagtcactac
     1741 tggggtttac gagggtttga cattacaaat agtgcagcta tgcaaaaagg attacagatt
     1801 tctggaaatc ataatttgat cgaagagatt catgcttatc ggaatggaaa tacaggaatc
     1861 caaatcagcg gtagctcaaa tgatcctttc gaagcatggc ccgcgcataa cttagtcaag
     1921 aactgtacat cttttgaaaa tgccgatcca ggatttgaag atgccgatgg atttgcggcc
     1981 aaactgacaa taggagaagg aaatgtattt gacggttgta tcgcgtatca taatgcagat
     2041 gacggttggg acctttttgc taaaaatgaa acaggttcga tcggaaaagt aatcatcaaa
     2101 aactcagttg cttatcgaaa cggctgggta ccaggaattg agggagaagg taacggtaat
     2161 ggattcaaaa tgggcggttc ttctttaacg ggccctcatg aattgatcaa tagtttgtct
     2221 ttcgaaaatc ttgcgaaagg aatcgattcc aatagcggaa cagatattat cgtcaatagc
     2281 agtacaagtt ttaataacgg ttcatataat gtggctcttt atacctcttc agcaggaaac
     2341 acagactacc atgcttctgg tatcttatct ttccgaacag agaatcttga gatgagagag
     2401 cagatccgcc cattgaatca aaacgaagat caaatctacc actcgttgaa ctactattgg
     2461 aatgaacgag agaaacaatc agaaaatact cttggacata ccatatcaaa agattggatc
     2521 gagtctctaa atacatgttc gaaagaaggt cagcagcctg ttacgcgcta tgaaaatgga
     2581 agtatccatg ttcatggact gatgcagatt aaaccgggga atcgtcaaac agaaaaggaa
     2641 agagtggatg gtcttccatt atctgtaggt gctatttttg acggagaaac ctcaccgtct
     2701 tcggaatatc cagagtatgc aatcgtacaa gaaccaaatc agacaaaacc aaatgaacaa
     2761 aataatccga ttattataca agaagcaaat ggtgtggcgg agaatgcaga aggaaatatc
     2821 attgaactga agccttttac agtttttgtg tcaactttca caccaaatca aggaacgcct
     2881 gtctttgaag atatgcgtta tttcccagaa aagatccaaa tcgttgaaac acagtcaagt
     2941 gctcaatttt ctaatcatac cgctattttt tcagcacctt caaaaggaga atatacgcta
     3001 gaagtcactt atcgttcgga aatatttgat ggggaaaaat ggtctgctca tacagaatct
     3061 gttacccagc aaaaagcgat cactgtgcga gaaactgccg atgtgccccc gggaaatgac
     3121 aaaccagaaa gagaaaatcc aggaaatgaa tcaccaaatg gaaaaccaaa tggaaaacct
     3181 tctcatccgg ataggacagc aaaagaaagt gaaaaaaatg gcactcaagg actcccaaaa
     3241 acgggagaat ttaataaccc gttgctagca ttagctggag gaattttgtt aatcggtgta
     3301 gttgtttatg tcatgaaaca gcgaaaaaaa taagtggaat ttctcctttt atgatgtaaa
     3361 acaattgact gaggaaagta aaaatagaag gaaatgagac caatagatgt ctcacttcct
     3421 tctatctttt tatagatgag gttctccttg ctgcttttga ttggctgttc ttattacttg
     3481 atgcaggaca gctttttcac aatctctcca ctaaacggtg ttcaatcagc tgaccctcgg
     3541 tattagctca acaaacggca aaatatgagg aactattttt ccgttttttt ctctaatact
     3601 caggtcagga cgctgatttc acaacctctc gataaacggt gttcaaaagc cagtttctcg
     3661 gtagtaagtc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttacta
     3721 cttgaaacta agcagctttt tcacaacctc taatacatgg tattccagaa gtaacttctt
     3781 cgaaaaataa gccgaaatgt cacaaaaatt tgagaagcga ttttcccaaa ttccttctta
     3841 tttcttgaag ctgaccactt ctggcacaac ctcttaccag attcgcactc ttttttctgg
     3901 cgctagatac atagcgtctt gttccgtgat accaaatgtt tcatagaatt cgtcaaggtt
     3961 ttttggttgc acgtttgctc ggagtttagc aggggcatgg acatcgattt gcagtaaaag
     4021 ttgttggtat tctttttttg cttttgtacg ccaaatcgtt gcccaattga caaagaattc
     4081 ctcgatagaa agatctgatt ccgtttttgc tgcttccaat gcacagctta gaccgcctgc
     4141 atcagcaata ttttccgaaa cggttaattt tccgtttact tttccgtcag caaaaggcag
     4201 accatcgaat tcttcgatca ttgcttgtgc tttgttttga aattgtgtaa gatcttcttc
     4261 tgtccaccag ttgttcaagt tgccatattc gtcaaataaa gcgccgttat tatcaaatgc
     4321 atgggaaatc tcatgagcga taacagctcc gattccacca taattagcag agcttgattg
     4381 ttctagactg taaaatggtg cttgaaggat cgctgccgga aagacgatca cattccgaaa
     4441 tggatgataa taagcattga ccgtgtcagc actcatttcc cattctgaac gatccactgg
     4501 tttgttccat ttgctgaaac gatcttttaa tgtgagtttg ctgaaaacaa gagtatttga
     4561 aagcaaagta ccaccctgat ctgcaggtac tgttttgaac tggtcgaata atgctgggat
     4621 cttatcgggg tagcctactt ggatacctaa gttatttaat tttatgacgg ctttttcttt
     4681 tgttgcatcc ccaagccagt cattttcttc tagacgtttt ttataaacgg cgatcatttt
     4741 tttcaccatt tgttctacgt cttttttagc agcttcgcca aaatattttt ttccgtagta
     4801 atcgccaact acttgatcga attgtccaga ggcaaggtaa tacgctgctt ttttctgagg
     4861 cattgcttcg tctgttccag acaatacgcg agaatagatt ccgctgactt ggcggaattc
     4921 ttctgataga taaccactaa gagaacgtac tgttttaatg atcatccagc ttttgaataa
     4981 cggaaaatga gcttctgtca ggatgtcatt caaatgatcg aagtacactg gatcagttac
     5041 gatcacttta tctggagttg tcccaatcaa acccgtgaca agttttttca agtccagttt
     5101 atctgtgtat ttaataaatg tatcaaaaga ttgcggatta tacattttgc tgtaatctgc
     5161 gttttcttct gcacttttta catgaggagc aatcaattta tcaaattgca ctgcttgttc
     5221 cgtgattgct tctgcctgac ttttttcttt gccggcaagc tctaataact gaacagccat
     5281 atcaaagaaa acgcctatta gttgtgcacc gttgggatgg tctgatgcat aatacgtctt
     5341 atctggaagg aataaagaag gcggataagc aaagaaggcg ttcgtttgcg cattcttcat
     5401 atctgcatct acatccagat taaatggcaa tggtaatgta tccaacagcc attctggaaa
     5461 ttgcttattc aattcgtcga aagactgcaa tgattcaact ttttcgatta taggttgaag
     5521 cggttgagca tgcaactcat ttcttcggtc ataatcgttt gccagttgat aatatgcaag
     5581 gaaatgtttc attttttctg aagacacttt ttctggatgg gcaagcagat cgtctgtttc
     5641 tcccatcaaa agttggtcga tcccgtcaac taaatcttgg aaaccgcctg tagctggttt
     5701 atctgcaggg atttttgctg ttttttgcca ttcttcattg actgcttcat agaaatcttg
     5761 tttcaatcgt tctttgttca ttcatcgatc gctccttttt tgtttcgtgt gcccattatc
     5821 ttacaaaatg aaggaattaa caaatagaac ataaaaaatt gaaaattcga acaatcaaac
     5881 tgatttgttt ttttcaatcc ttcacttata atgaaaaaaa ggaggcgatc ccaactgaat
     5941 caagtagtgg ataaaccttt atatttcaaa gtagataaaa aaattaaaaa attagccagc
     6001 actcagcagc tgcagtcaag aaaaagtaaa ttgctttttt tagctctggt ttttgaagat
     6061 caaagttatg tgattatcga tcaatcagga catccggtag aatattctcc agcaaaatat
     6121 acttatcaag agggtctttc ttgtaaaaaa tggaagctga tcaatgaaga gccaatcgag
     6181 ttatctagat ggatcaacag aaaagaagat attcccgttt tgatcgaaga aaaaaggtca
     6241 ggaaaggaac tcgcaaattg ctgggtggga ttgccagaag aacgtttttt gaggtataag
     6301 aaatgggcta ccccctcagg ctatctttgt ggtacttacg cggcagcagt tctccttgcc
     6361 tattatcaag actatcgtaa ggggtggatg cttccaaatg agattcgcaa gaaaaatacg
     6421 gctgattcgt tggttttgac gaaggcattg cgtagccaga tccaaccact aggacttcct
     6481 acgattcctt ttcaggttag tacagggatt tctagttttt taaagaagaa tggcaatcat
     6541 gagcgtgcac gagcaactct tctaggttca tggcagcgag ctacaaaacg tatacgtgaa
     6601 ggcaaacctg tgatgattgg tattttgaaa gtacttggca gtacatatgg caatcattgg
     6661 gtgacagcgt acgcttattt tgaaactgaa acaggagaac gttattacaa agtacacgac
     6721 aactggggcg attatcataa agtcattcct gccagttgga gtaacggaac agtttcactt
     6781 ccttaagaat ttgctgaaat taacagaaaa tcttggaaaa atatgttaaa ctatcgaaga
     6841 atagagaagt tttggggagg actacatgag taataagtat caggatgaca cgttgaagat
     6901 ttttagtttg aatggcaacc gtccattagc tgaaaaaatc gcgaaagtgt tcggaacaga
     6961 attaggtaaa agcgtcgtga agcaatttag tgatggcgag atttccatca atatcgaaga
     7021 aagtattcga ggggatcatg tgtatatcgt tcaatcaacg aatgcacctg tcaatgatta
     7081 ctatatggaa ctactgatca tgatcgatgc aatgaagcga gcaagtgcga aaacgatcaa
     7141 tgtcgtattg ccttactatg ggtatgctag gcaagaccgc acggcgaaac ctcatgaacc
     7201 gatcactgcg aaattgatcg ctaacttgat cgaagaagca ggggcaactc gagtactgac
     7261 tttagatctg cacacggttc aagtacaagg attctttgat attcctgtag ataatttatt
     7321 tacgatgccg ttgtttgctc attattaccg tcaattaggt ctgacgggag atgacatcgt
     7381 agttgtttcg ccaaaaaaca gcggtgttca gcgtgcacgt agtctttcag aatatttgaa
     7441 cagcacatta gccatcgtag atcatgcaga tgatgcttca actgagggtg gttatgtgat
     7501 cggtgatgtt caaggaaaga catgtatcat ggtagatgat atcttgaaca caggagcaac
     7561 gcttgcacga gcagcaaatg tattaaaaga aaacggcgca aaagaagtat atgcctgtgc
     7621 gtcacatgga ttattgtccg atcatgcgaa aagtatttta gacaatgcac caatcaaaga
     7681 tatttgtatc actgattctg ttttcacaga agaaaatcgt catccagaaa acttaacaat
     7741 cgttacatgt tcagaattaa tgggtgaagc ggtcaaacgc atccatgaaa atacaccgat
     7801 gagtccgtta ttccgtctgg aagaaaaaga attcgaataa acaaaaaaaa gagggaaaga
     7861 agttgtgaca gaagtgagca gcttcaagga gctgcgacaa gacttttgtc acagctcctt
     7921 ttttctatgc ccatgaaacg tcctctagac aaaaatgagc tcttctttgg tttgttcgct
     7981 attttatgct agaatgtgcc tagcaataat ttggaaggga tgaatgaagt gaaaactatt
     8041 tatctggatc atgcggcaac tacccccatg catccacaag taattgaagc gatgacggca
     8101 atcatgcaag acacgtttgg aaatccttca agcatacatg gatttggtcg ccacgcgcat
     8161 gaaaaattgg aaacagcaag acaaatcatt gcagacagtc tgcaagcaaa acctcacgag
     8221 atcatcttta acagtggggg aacagaaggg gataatacag ctatcttaga aacagcgttc
     8281 tcgcgtcaaa aagaaggcag acatctaatc actacagcta tcgaacatcc tgctgttctt
     8341 aataccatga aatatttaga gacaaagggg tttgacgtta catatctgcc tgtagatgaa
     8401 aaagggaatc tgtcgatcga agaggtcaaa aaagcgttac gagaagatac gatcttggtc
     8461 tctgtgatgt acgggaacaa tgaaatcgga aatttgatgc caatcaaaga aatcggtgaa
     8521 cttttagcgg atcatccagc ttatttccat acagatgcgg tacaagcgta cggaaaccaa
     8581 acgatccatc cagaagaatt aggaatcgat ttattaagta tctctgctca taaaatcaat
     8641 gggccaaaag gcgtcggttt cttatataaa cgagacggag taaatatccc tgcattgctt
     8701 ttaggcgggg agcaggaaga aaagcggcgt gcaggtacag aaaatttagc agggatctgg
     8761 ggtatggcaa aagcagttga actgctgtca cctgaagaac gtgaagcacg taacaacaaa
     8821 tataaaggat tccagcaatt gattcttgat acattagaag caaacgaaat cccttatcaa
     8881 gtaaatggtg atttaacgaa taaactccct catgtgttga atcttcgctt aattggcgaa
     8941 gcaaatgatt tgctactgat gaagcttgat cttaatgggg tcgctatttc tactggttca
     9001 gcttgtacag caggaaatat cgagccttca cacgtattag aagcaatgta tggagaagat
     9061 acaccgatac taaaagaatc catccgtatc agctttggtt tgggaaatac cgaagacgac
     9121 atccagtatt tccttgatca attagttcgt gctgtcaaaa aataactagt gaagtcattc
     9181 ttatatgaac agatgtctga gagaacgcct tcatttttta gggaacttaa ctgaaaaacc
     9241 tagtaaaaat caggataaac ttttataata aagagaaact aattttatcg aggtgaaaat
     9301 catggcattt gaaacaacag caacggtact gggcgcacca attagctatc gtttgcatcc
     9361 tgatgcaaaa agatatacat tgcgcgataa tggatttaca gaaacaaacg gaggcaatta
     9421 tcaattgatc cgaccattag atgccacgcc gcaaagcaaa gaaggattca aattaaaaat
     9481 cactgtatca aaagatattc aaacattgaa aatgtcgatc actacagcaa atggattgaa
     9541 agcagtcaat attttcaaag atccaaaaca gaaaatgagc caagataaat tttattttct
     9601 gatggatggg atgattagcc gtgggttatt cgaaaaagtc gaatgatctg tggatataaa
     9661 aagacaacta gttttgaaac ggcctattgt tagatgacta actttgtaag gacgacgcaa
     9721 attagttgtc ttttttattt ttaaatttaa cacatgttgt tatttttaat attttgctga
     9781 tttattgttt ctaagtaaag aaatttaaat tgaaacgatt gttatttagg gaaaaaggta
     9841 ttttttgaaa aaagaatccc gtataatgat tgttgtgcaa acgctataca aaatgaaaaa
     9901 gaaaagaggg atgtttatgg aaaatgaaca gtcggtcgtt ttaacgaatt ggaagagaaa
     9961 ttatttgttc tttttatcgg gacagttttt gtcaggaatc actagtatgg tcgtccaata
    10021 tgcgatcatc tggtatttga caagagaaac cggttcggcg acaattttga gttttgctac
    10081 tttactagga atgattccca tggttttact aagcccattt gtaggaccgc tagtggatcg
    10141 ctgggataaa aaagctcttt tgattgtcac ggatattatt gtagcgattt tcgcgcttat
    10201 tttagcagta gtcggaacga tttcagaatc cttcccgatt tggctagttt ttgtgtcttt
    10261 gtttatgcgt tcggtcgcac aaacattcca aatgccaacg atccagtcga ttatgccgac
    10321 aatcgttcca tcttctcaca taacaaggac gaatggacag ttaggaatgg tccaatcagc
    10381 gaatttcatc attgcgccag ctctaggtgc ggctttgttt tcagtcgttc ctgtcaatta
    10441 ccttatttta ttagatgtat tgggggcagt ttttggtgtc ggcttattga tttttgtgaa
    10501 gatcccaaaa gtttctcctg aaatattgga agttccgctt actattttta aagatgcaaa
    10561 atttgggctg cagcaattga tggataataa agggttatgg tacataacga tcaatggtgc
    10621 atttgtgatg ctgttgttca tgccagcaat cagtctgtat ccattgatga cgctagatta
    10681 ctttggtggt tccgttggac aggcgggagc agtggaagta gtctacgcag tcggaatgct
    10741 cttaggcggt gcactgatca gttttatagg aacatggaaa gaccgaatga aacctattat
    10801 tatagcctac atcattatgg gcctgacgat cggtgcaagc ggattggttc caaacgatag
    10861 tcaagggttc ttgtactttc ttatcttgaa tgcaggagca ggttgtgcaa cgccatattt
    10921 caatacactg ctgatggcaa tgatccagca gagttatgaa tcgaatgttt taggtcgtgt
    10981 cttagggaac ttcaactctt tgatgaacct ggcaggtcca attggattat tatttgcagg
    11041 accattagct gatcgtttag gggtagaaaa aatgttcttg ttttccggaa tcgggatttt
    11101 attatgcgga atcgttttat ttttaacgtc agctgcccga aattatgata aagaattaca
    11161 gaaaaaactg gtaaaagaac accatgagca aaaagacgaa tagtatggaa tggagttgtg
    11221 acagaagtct tgttacaact ccatttctga tcctaatgtt cctgtggcaa taagcctact
    11281 caaatgaaaa atatgagtaa ttatctttat ttgtttaata cttgatatag ggcagttttt
    11341 tcacgaccta tcgtacttcc tctttgcttc atagatttct ttgatttgtt gctcagataa
    11401 cggagtgcca aatggtagtt tttcctttaa gagttctctt tccggtgcgt ctacgcctac
    11461 attgacatcg ttctcgatag gtacgctgta atgatggata tgtccatgaa gattgcggat
    11521 agtgtcgtta ggcccgagca acatcggata atgagtcaag taatattgtt gatggtcgaa
    11581 tttaacgatg gcacctacat cataaaaata aaatttggga cttccgtcag taagcctagg
    11641 atcatttttt tctaaataac ggaaaaaagc gcgactgtca tggttccctt tgatcaagtg
    11701 gattgttcct tgcagttgag tgaccagttc caaaatttct gcatttgctt tttcatattg
    11761 cggatgcata gcaaggtcgc ctagatgata aacatggtcg gtttctttta ttactgcatt
    11821 ccagctagtg atcaactgtt ggttcatttc atccacattt gcaaagagcc gcggagcaaa
    11881 gtcgtttttt cctaataagc gttcatggaa aaagtgcata tcactgataa agtaattcat
    11941 gtatcttttg cctccctttt ttcttagagt aaacaaaatc acttatctga gcaactcata
    12001 acatctaaaa agaaaaggtt gtaaatgaga cgtgcagctt taagcgataa gaagcaattt
    12061 tgaaaaatag tttttcacaa tttataaaat tattccttat tgccgaaagg ctggcccttt
    12121 ttatgagtat gccaattttt tatatcgaat gctcaaaaga tgagtgattt tttggttgac
    12181 tatcatgttt gtgtactgaa taggtccagt agaacagtat ttttacgact tgataattaa
    12241 gggatgaaat tttcagaaat atgacgtata atgtaaaata ctgaaaagtt gcgaccttca
    12301 actcgtagat gtttcagaat ctaattgaaa tgatggtgat atcatgacag acaacagcaa
    12361 aacacgcgtt gtcgtaggga tgagcggcgg tgtcgactca tctgtaacag cacttttgtt
    12421 aaaggaacaa ggatacgacg tgatcggaat attcatgaaa aattgggatg acacggacga
    12481 aaacggtgta tgcacggcca cggaagatta taaggatgta gcgaaagtag ctgctcaaat
    12541 cgggattcct tattactctg tgaattttga aaaagaatat tgggatcgtg tatttgaata
    12601 tttcctagcc gaataccgcg caggacgtac acctaaccca gacgtgatgt gcaacaaaga
    12661 aatcaaattc aaagcattct tggattatgc aatggatctt ggcgccgatt atgtagctac
    12721 tggacattat gcgcaagtca ctcgcgatga aaacggcgtg gtccacatgc ttcgtggagt
    12781 agacaataat aaagatcaaa cttacttcct tagccaatta tcacaagaac agctttcaaa
    12841 aacgatgttc cctctaggcg gcatggaaaa atcagaagta cgggcaattg ctgaacgcgc
    12901 aggccttgcg actgctaaga aaaaagattc aacgggaatc tgctttattg gtgaaaagaa
    12961 cttcaaacaa tttttgagca actatctgcc agcaaaaaaa ggaaatatgg tcactcttga
    13021 tggtgaagtc aaaggacaac atgctggctt gatgtattat acgattggtc aacgtcaagg
    13081 actagggatc ggtggcggag gagattcgca agaaccctgg tttgttgtag gaaaagatct
    13141 agcgacaaac acattatatg tggggcaagg gttccatcat cctgcattgt atgccacaag
    13201 cttggatgca agtgaaatcc actttacgac gaatgaacca atgccaaaag aattcaagtg
    13261 tacagcgaaa ttccgttatc gtcagcaaga cgttcctgtg acagttcgct tattggatga
    13321 taatcgtgca gaagtcgtat tcgacgaacc tgtacgtgca atcactcctg gacaagcagt
    13381 tgtattttat gatggaatgg aatgtctggg tggtggtttg atcgaccacg catatcaaga
    13441 aacaaaagtt ttacaatacg tttaagcgat attaaatgaa tcaaaacagc tatggctaac
    13501 aaaagaaaca ccttttcttt tggatagcat agctgttttt ttgcaataaa attaattttt
    13561 a
//
LOCUS       DACCVH010000073        13526 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.073, whole genome shotgun sequence.
ACCESSION   DACCVH010000073 DACCVH010000000
VERSION     DACCVH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.073"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(334..894)
                     /locus_tag="IVV98_002186"
     CDS             complement(334..894)
                     /locus_tag="IVV98_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7807815.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            1036..1650
                     /locus_tag="IVV98_002187"
     CDS             1036..1650
                     /locus_tag="IVV98_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7807816.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            1839..3719
                     /locus_tag="IVV98_002188"
     CDS             1839..3719
                     /locus_tag="IVV98_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7807817.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            3798..4025
                     /locus_tag="IVV98_002189"
     CDS             3798..4025
                     /locus_tag="IVV98_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAP7807818.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            4030..4572
                     /locus_tag="IVV98_002190"
     CDS             4030..4572
                     /locus_tag="IVV98_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7807819.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            4799..5515
                     /locus_tag="IVV98_002191"
     CDS             4799..5515
                     /locus_tag="IVV98_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP7807820.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(5575..7593)
                     /locus_tag="IVV98_002192"
     CDS             complement(5575..7593)
                     /locus_tag="IVV98_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAP7807821.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(7606..8604)
                     /locus_tag="IVV98_002193"
     CDS             complement(7606..8604)
                     /locus_tag="IVV98_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807822.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            8802..10043
                     /gene="sstT"
                     /locus_tag="IVV98_002194"
     CDS             8802..10043
                     /gene="sstT"
                     /locus_tag="IVV98_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP7807823.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            10190..10825
                     /locus_tag="IVV98_002195"
     CDS             10190..10825
                     /locus_tag="IVV98_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP7807824.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            11016..11756
                     /gene="truA"
                     /locus_tag="IVV98_002196"
     CDS             11016..11756
                     /gene="truA"
                     /locus_tag="IVV98_002196"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP7807825.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(11901..13499)
                     /locus_tag="IVV98_002197"
     CDS             complement(11901..13499)
                     /locus_tag="IVV98_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP7807826.1"
                     /translation="MLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAEN
                     YNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTP
                     IYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTL
                     ILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT         4530 a         2135 c         2633 g         4228 t
ORIGIN      
        1 tgattcccct tgaaaatgaa ttgaggtaaa cgagaagaat tcaataaact ggatgataaa
       61 aatataatat gactataaat tggttacagc ttcaacctat aagttgtaat aaattagcct
      121 aaaagtaatt tattaatgat gaggtgaatt tgattggtac aacaagatat atcacttaga
      181 gagggagaag cagcactaca aactactttt caataagtag gaattataga aattttactc
      241 aaaaaatctt cagtaaacaa tttggctaaa taagattcag ttgttatacg agaaggttac
      301 ggttcttctt aactaagctt agtatgtttt tattcaaggc atgattttct ctatgtgatc
      361 attcagtttc tgtaagagtt ctaataattc ttttttggag tacttgtaat tgctttctac
      421 ccaccgattg agaacggata gacaaccttg gacgtggtac gtagtaaaga atctcatttc
      481 ttctgtgata atcgttttct tgtcttcata tagccatatg ttcagatagt tttcttcaat
      541 aacttgttta actttcttct gaaacgaaat atcaccatgg ttgaggataa ataagcgata
      601 taaaaaagta tttgcgtaaa catagtcaat caagcgagtg tatagttcct catagctatg
      661 ggctggatca taagagagaa tttcatttag atcccgaaaa aagttgcttt ctaattgatc
      721 atatagatca tagatatcct tataatgtgt ataaaaagtc gaacgatgta catctgccgt
      781 ttctgttagt tcgcgtatag tgattgcttg aatcttttta tttactaata atgtggatag
      841 tgtttcagcc aaagcttttt ctgttttttt gacgcgtcta tctgtctttt tcatttacct
      901 atctccttat ccgacatatc aaagcaaagc tgtcgcttaa tcgacaaact tatagatgat
      961 tgattataga tagtagacac tgtgtctatt ataatgtaag tataacacaa tcattgaagt
     1021 tgaggaggcg aaatgatgaa actaactttt aaacccttag aaaagaaaga ttacaaaaaa
     1081 gctatctatt ttgctgttga aggaatgaac tttgagagat atatggaaaa tgaacttctg
     1141 ctgaatcttt acggaagata ttttttgtat atggagttga atcgagcaac tcaaattctt
     1201 gctttgtatg cagaggacga gttggcaggt gttttgctgg cggagataaa aggagaaaaa
     1261 aagaaacatc gttcttttgg acagcaaata tatgttaaga tattcgattt tttacaaaat
     1321 atatttgcta aagaaagtaa aggagcttac gagacagcaa atgaacaaat gcttgcagca
     1381 tatttaaaga agcattcgcc agatggagag atcatttttt tagctgcaaa tcctgatttg
     1441 aaaacaaaag gcatcggtac caagttgcta acagaatttg aaaaaagaga gaaaggaaaa
     1501 gaaatattcc tttttacaga tagtggctgt acgtatcaat tctatgaacg acgtggattt
     1561 gaaagactaa aggaaaaaat tagcaagata aaaatcttag ataaagaaat agatctccga
     1621 tgtatgctgt acaggaaaat cattcaatga aaatttcgat agaaacgaca atagttggca
     1681 agatcacttt tagtgagtct tcttgctaac tattttttgt agtgtattct accaaaagaa
     1741 aaccgccttt ttgactaaac ttgatagtgg tcaatttttt atgatggata agtatctata
     1801 cttagtctcg taagaatgaa aggaaaagag ggagaaagat gaaattacaa aagtggatcc
     1861 aagagcatcg aaatcatatc accgccttat cagctgtgtt gattattttt ggttttatcg
     1921 gaaaatttac tggttttgtc ttgttctata acattgctct agccatagct tctattattg
     1981 cggtcatacc tattatgatc catgcgtatc aggcagtgaa agtcaaagtt atctcaattg
     2041 atttactcgt tactattgct gtgcttggtg cctttatgat cggagaatac aaggagtcag
     2101 ctatcgttac attcttgttt ttgtttggta gctatctgga acaaaaaaca ttgaccaaaa
     2161 cgcgggagtc aatcaaggct ttgaccgaga tggccccatc tactgctagt gttgtccaag
     2221 aagatggaac gactgaagaa gtggaaatcg atgacgtgga agaaggcgat atcgtcttag
     2281 taaaaactgg tggagctatt cctgtggacg gacgagtcat tgacgggaaa gggtatgcgg
     2341 atgaagccgc agtgactggt gaatcacgac aagtcgtcaa aatcagtgga gatgaagtct
     2401 tctctggaac gattttagca gatggctacg tgacgattga agcaactaag gtcggagatg
     2461 atacgacctt tgccaaaatt atcgaattag tagaagaagc acaagatacc aaatcccatg
     2521 cggaaaaatt cattgatcga ttttctcagt attatactcc aaccgtttta cttattgcgt
     2581 tggttgttgg tctgattagt cgtgattttc gtttagcaat cactgttttg gttcttggtt
     2641 gtcctggcgc tttagtcatt ggtgcgcctg tttcgaatgt agcaggaatc ggtaatggag
     2701 cgaaacgggg catcttagtc aaaggcggtg aagcaatgga tactttttcc aaaatcgata
     2761 cttttgtctt tgataaaact ggtacattga ccaaaggaac tactgctgta tccactatca
     2821 agaactatac agaggatgaa ggggacagct tagctttagt ggctcgatta gaaacgttat
     2881 ccgatcatcc tctggggcgc gccgtgatcc attatgctca ggagaaagac attgattttc
     2941 aacaattagc agtcaaagat aatcagacaa tcaagggaca aggaatcaca gctgagattg
     3001 atggtcatac agtttgtgcg ggcaacacca aattgattgc cgctcacaaa ctttctctca
     3061 caccaaagca agtacaagat ttacatcaat tacaacaaac aggcagctcg gtcattattg
     3121 tagcaatcga caaaaaaatc actcaaatca taggtgtgtc agatgtgatt cgaccagaag
     3181 tcgctgaaca attagctaag ttgaaacaag caggagcaaa acagttagtg atgctgacag
     3241 gtgataatca gatgactgct gattatgtag ctgatatgtt aggcattgat gaagtccatg
     3301 ctgaattatt accagacgaa aaggttcaat ttgtgaaaaa ataccaagaa caaggattgc
     3361 gcgttgcttt tattggagat ggaatcaatg attctccctc tttggctgcg gctgatatcg
     3421 ggattgctat gggatcagga acggatgttg ctatcgaaac gagtgacgtt gtcttgatgc
     3481 aatctaattt tgaatcgttg gttcatgcct accgcttggc taagaaaact gttttaaata
     3541 cccgtgaaaa tgtagtgatt gccattggtg tcgtcttatt tttactcaac ggcttatttg
     3601 ccgggtttat ttacatggct agtgggatgt tcgttcacga agctagtatc ttgatcgtta
     3661 tctttaacgc gatgcgttta ttgtattttg gacacgaaag caaagaagaa aaatcgtaaa
     3721 acttgataag aatcaatttt tttatggaag ctgtaatcta gaataagact atcaagaaaa
     3781 aggaaggaag aactacgatg aaaaaaatta ttatgcaatt agatacacta gcttgtccaa
     3841 gctgtatgca aaaaatcgaa catgcggttt ctcaacagcc tggggtaagc aatacgaaag
     3901 ttttgtttaa tgcgagcaaa atcaaagcaa actttgatcc agatgaagtc caccctgaac
     3961 aattagctgc agttgtggaa aaattaggtt atgaagtcca atcagcaaaa gtaaaagagg
     4021 cgtaaatcaa tgaatatagt ggaagaaaaa tttgttcaag aaacaaaaca agcagatatc
     4081 gaccatcata aaccaactgc tggcgccatg gtggggcatg tattagcaaa ttttaaatta
     4141 gaagaaatga aattgatcca agcacaattg tatgttttgg gtacatcttc gcaagaatta
     4201 agtacccttt tttcagaata tgctgatcaa gaagcgagat ggttcaataa aatctctcat
     4261 gagttagtga ttgaaaatga aatcgttccg tctactttag aagaagtcat gcgttatgga
     4321 aaaatttacg aacatggtca aaacaaatat ttaccagcct caacaatgtt ggaaaacttt
     4381 gcaaaagatt ttgatttcca aaatgtcttt atcacacggg caatcaaatt agctgaaaaa
     4441 gaagaaaaat atggcttgca acaattgctt gttgaacttt taagtttcaa taaagaaatc
     4501 atctaccaag tacaaagact ccaaggaaaa actgtccgac aagatttgga tgaggaagac
     4561 gatgatgact aaaagtctat gtttcttcaa atacaaatat aaagcgtgag gtaaattgga
     4621 aaatcacgaa gattaaaata aaagaagcac ccgctgatgt attacagaca acatcagcgg
     4681 gtgcttctca gtttttagaa gatttgaaag attgatgaga aaatacgaaa aatcaataaa
     4741 atcacattgc ttatttgata gaataaagaa gtgggagtaa tcgaaaggag ttttttaatt
     4801 gaaaaaaagg attttagtaa caattggtct agcttttttg ttagctggtt gtaccaacgg
     4861 gaatgaatcg aaaaaagaat caacaaaaga aacagcgaaa gcaacagttg caactactac
     4921 aacaactagc acagagagca agtcaactgc agcaagtaca gaaacagcag atacctctac
     4981 ttcgtcagag tcttccaaaa cgactgaaac aactcaaaca tctacttcaa gttcttctgt
     5041 agaggcttca tcttcctctt cagaaagcag cgaacaagtt gaacaaacac tgtggaatgc
     5101 agacaaatcc gcacaattag aggcatttat gaccaaatgg ggccaaacaa tgggacaaca
     5161 atacaaaagt tatacgaatc aaatgagtgt ggacttatat ggtcttaaag tccctcaagc
     5221 tattttgaac ggggagtgga agatggctat tggtggagtg cctgtttctg cagaatggtc
     5281 agaaagtggg acaggtcaag cagactatca aatcacagcc gtctattccg atgcagagac
     5341 agaaccatat ctgaaaaagc acgtctatct attcgggttt cagcaaaatc agccaaaagt
     5401 attggtgaca caacaaaatc aggggaatcc cgataattat ctttacttca acgagacagc
     5461 gaataatgaa ttgaaaaatg gctttaatca aatcgtttat ggacaagcaa attaatgaga
     5521 taaacaaggg gttgtgacat gtcttttatc acaacccctt gctcagttta tttgttagtc
     5581 ttttattttt tgtgtcgccc atgttgcact gtactggtta cctgcaacaa gatcatattg
     5641 tatcagacga taatcttcta gaatttcttt ttgtttctca gttaaatttt tttcttggat
     5701 aatttgacta tcctctgtaa caaagacctg ttttccatta aaacgattag acaagctttc
     5761 tgtaggatca attgttaatg caggtagatg attagatact tctgtcaaca acgcatagta
     5821 aggagttact ttgatattcg catgctcaag agccatagca ccaaagttat taggagcaac
     5881 aacttcttta tttaacgtag ctgcttgttc acgactatac ttgttgttat aaatgaaata
     5941 atctgtctgg tgctgttcta atccatattt tttcgaatca ttcccactat agattgcggg
     6001 taaatggtca ccataaaaaa caaaggtaat cggtttatcg attttgtcga tttcttggat
     6061 gaattttttt actgctgtat cggtatagtg aaggccttgc atataagttt gtaattcttt
     6121 tcttctatta ggaatgacag cagttccttc agcagtgtag ttcaattcac tatagtaatc
     6181 atcataaggc atatggtttt gcatagtgga taattggatg aattgtgacg tttccgtatt
     6241 gctttgtaaa gctttcaagg tttctttgta tgctgaatca tccgatatgc gtgggctttg
     6301 ttctatttta tccgtataag ttaatttatc cggactgtct aaataataga acctgtcaaa
     6361 accaaattta tcaaacactt gttttctgcg ataaagagca gctgtaaaag gatggatggc
     6421 tattttttca tcgaatagat cggtaatatt tggacttatt ttctgacgct ccactagctg
     6481 ggtataaggt gtaactaacg aagcagacag gttactgata ctcaagcctg tcagtccttc
     6541 ccattccatg ttagctgttc cgccaccata accgacggat aacatcaatc ctcctgttcc
     6601 ttctgttata atgcttttga tgtaaggaat agggtctgta ggtactgtca gattagggac
     6661 acgtgcagga tcactgaagc tttcacttaa attgagaacg atcgtctgat tgtttaacca
     6721 gtcacttctt gtttggttga tttcatctgc ctttgtgttg tactttttca ttattccatt
     6781 aattttttct ttcgaatagc cagcaggttc ttccatgatt ttaatgtcga tattgtttag
     6841 gaattgaatg actggtccgt tatcttttac ggcgccttgc tggttaaaga aagtcttgtt
     6901 tactttaaat aaattaaaca gcaagaaaga aggcgaattt ttgtgattaa tgaaaaagac
     6961 acccgaaaaa catcctaata atacagcgat actgataaat cgacgtttcc aatgaatctt
     7021 caaggaatac tgtttttgta gtctacgttg tacaataata ctagtaatca ataataggag
     7081 aaggatcaat ccgcccacga ttaataagac tgggctaacc atcgataata gttctgacaa
     7141 tccggtcagc atttttaaat ctgaaggaaa gacaggctct tcccgcattt ccattttgat
     7201 tactgtcgaa atagtgagca gtaagttaat gatcaaggta gcagtcaagg cgtaccaaaa
     7261 acgattggaa atcaacaata gtaagaagaa aaatcccata ataatgatga ttgtcaggat
     7321 catgggtgct tgtcgctgag taaatatttt taaggcaacc tggatagttt ctttccaacc
     7381 ttcttttggt tctaaaacga aaatctgcac gaaggtaaag cagtaaaaaa atgctgcaac
     7441 taaaaaataa cttttatgaa caaaaagcca atgaattctt tttttccaac gctgagttaa
     7501 ttgttcaatc gaatcaaaag cgaagtattc gatgaaacga tgaatgaaac ggattttttg
     7561 tatataaaat aaaaagataa ctaggaggga cactgctaat aaatatcaaa taaaaaactg
     7621 cccgatattt atcagccatg ccttccctga gtttggaaat tcacgtttca taaatgtaga
     7681 tacgcgataa gaaactaaag ggaaattaca tataacttga gtgacaatca aaaatacagc
     7741 aagaaaattt cctcttcctt ttatacctaa tttatcagat agcatttcta aaaataaaaa
     7801 cgaagagaaa gtataataca ttgcgaagag agaatatggt ttagaaaacc tcagcgctgt
     7861 atctgtattt cctctgatga tgagtgaaat ttgtgtcatc aaaataatca aaccgaataa
     7921 aacaatcaag ctgataaata cttgaggaag cttatagcgg accttttctt tccagttcca
     7981 ttctttcaaa ccataaccca ttaaaaataa ataaaaaatc cataaaatac tctgtccatt
     8041 ctgtaatgca aacgggtctt tattaaatag agtagagcag ccaactaatc caattgttaa
     8101 aaataatagt agatatttaa ttgttgtttt cgataattta tttaaaaatc caactgtata
     8161 aggaatacta caaaaaagca aagtacaaga aacagcataa gtaaagtaat tctgactgat
     8221 aggtgttagg ataagccaat aatcacgaat attcaagctg ccagcttgta cgtaaaaaaa
     8281 gatattgcaa actagtgtgg ctattaggaa tataaaggca aaacgactta aataatgtaa
     8341 aacttttaaa cgggcgattt tttgatattg gtaacccatg taaagtggga tcaaatttgc
     8401 accaataaca acggaagttt gtaaaaatgt atagatgtag aatcgaccag ggtttgttgc
     8461 atatgtagga atagtgactg ctgaaatcaa tatacgctgt aaaaccatca ttatacaagc
     8521 gacaaagatt gtcaggaagc cataactctc cttctttatt tttttcaaga ataaacacct
     8581 cacaaaaaaa ttggacaaaa acataagaaa acgtttcctg ataagttgcc cattaataac
     8641 atcctaactt agaatatctc aaaaaacaac gtgtagacag aaaaagtaca aaattagcaa
     8701 gaaatggttg tttgtattgt tagaattttt agaaaattat acctttagtt tctttgcata
     8761 aaatgataca atgattgtta aaattgtgaa agggtggtca tttgttagag aagtttttgg
     8821 atatgtcgtt agttcaacgt attgttgttg gtattttagt cggaatattg tttggtatct
     8881 ttttccccac atggacattt atttcaatat tgggaacgtt gtttgtcagt tgcttgaagg
     8941 caatcgcacc tattctggtt tttttcttga cgatggcgtc aattgccaag cataaaattg
     9001 ggaataagac attcgtgaag cctattttga tcttatattt agtgggaaca ttgctttctg
     9061 cacttgtagc agttattgta agttcaattt ttactgttcc tattacttta caagaaacag
     9121 tatctgaaaa agcaccgcaa agtttggaaa gtgttttatc tactatgttg acgaatgtca
     9181 cacaaaatcc tgttcaatct cttattgatg cgaattacct tggcgtctta ttctgggctg
     9241 tattgttggg actagctttt cgagcacgtt cagaatcgac aaaagagttg gtggatcaga
     9301 tatctatagc gttgtcacaa gtcgtacaag tgattattgc atttgctccg atagggattt
     9361 taggattggt ttatcaatca attgctacga ctggaatcgc tggattggca gagtatctgc
     9421 agcttttact tgttttgatc ggtacgatgc tgtttgtcgc attagttgtg tacccattcc
     9481 tcacgttttt gtttattaaa gaaaatccct atccattgat tttcttttgt ttgaaagaaa
     9541 gcgcacttcc cgctttcttt acccgaagtt ctgccgcaaa tatcccgata aacatgatgt
     9601 tggctgaaag attgaaattg acaaaagagt cttattccat atcgatcccg ttaggtgcta
     9661 cgatcaatat gggcggtgcc gcgattacca tttccttgat gacgttgact gctgtacatt
     9721 ctttagggat tgaagcacct tttgttttga aagtcctttt atgtattttg tctgctttag
     9781 ctgcttgtgg agcttcaggt gttgcgggcg gttcactgtt attgattcca ttagcatgta
     9841 gtttgtttgg tatctctaat gatgtcgcga tgcaaatcgt cggtattgga tttattatcg
     9901 gtgttatcca ggattcaatg gaaactgcct taaattcgtc aagtgatctg ttgtttactg
     9961 caataggaga gctaggcgcg cgtaaaagaa gtggggaaaa aatcaaattg aaagattgtt
    10021 tagatggatt aagtgaacgt tgaacgttag atatttagta tttttaaaat gattcgagtt
    10081 tttaatgagt tatatagatg ttcgtgtaaa tagaggtttc tgttaaatca agataaagtc
    10141 gtttataata acaattaaaa gcataggtaa ttgttattgg aggcgtatca tggatttttt
    10201 acgtaaattt ggttttttct ttttattatt aggcgtgctg agtgattttt tgactccgta
    10261 cgtattagga ttgtattatc ctgaattaga tcaaatgaag agcgtgatca gtgtatttgg
    10321 agaggtttcc agtcctgtaa gaaaagcgtt tcttatttgg tctgtggttt cagggatctt
    10381 tttcatcctg tcattgcctg cattgtatgc tgcatttgtt agtacatctc gtgtgttagc
    10441 taccctagtt acagcagcca tcgcgttcta tggtataggt gattgtatct ttacaggttt
    10501 gttcagtatc aatacccatg aatcttcgtg gaatgtctcg acatgggtcc ataatatcgg
    10561 atcaggttta ggttacagtg gttttttatt gtttccagtt cttcttttct tgatctatcg
    10621 aaaaaatggg caaatggacg taagccactt ataccttgga ctgtctgtga tcagtttgct
    10681 ttttgcggcg atttatggac tggcaagaat tccttctata aattcttggc cattactgaa
    10741 taaaataggt ttttgccaaa gaatcagttt tttctttaat tatgtgccca ttgcctggtt
    10801 gagtatcttg catctcaaac agtaaaactt gagccgtcaa attgaacagt cagcggatac
    10861 ttcatccggt ggctgttttt tgtttttctg aaatatatat ttccacagtt ttcttgtata
    10921 gcttctgtct tagagaagca aggagctata ttttgtgcta caatcttaaa aaggtagaga
    10981 gaagaccaaa tggaagacag aggagccact aaaatatgag aaacatcaag ttgacaatcg
    11041 aatatgacgg aaaaagatat tcaggatggc aaagacttgg agatgacgat aaaaccattc
    11101 aaggaaaaat cgaaaaagta ttgcatcaga tgacaaatga agagatagaa attattggat
    11161 caggaagaac agatgctggc acccatgcgc gaggacaagt agcaaatttt aaaacaaaca
    11221 cagaaattgg actggcagaa atgatcgact ttatgaatcg ttaccttccg cgggatattg
    11281 tcatcaaaag aatcgaagaa atgcctgagc gcttccattc aagatataat gcggtgggca
    11341 aaaaatacag ctattatgtt tggaacaacg tgattccttc agcatttgag cgaaaccaca
    11401 gcttttattt ccctcaagag ttggatatgg acaagctgaa tgcagcttgc gaaaaattag
    11461 tgggtacaca tgatttcatt ggtttttctg cattgaaaaa atcaaaaaaa tccacagtgc
    11521 gtacgattga tgaattatct atcgaacgaa agggagaaat gcttcatttt acttttgtcg
    11581 gagacggatt cttatataaa atggtgcgga ttatcatggg gacattacta gaaatcggca
    11641 caggtgccat gccgatagaa acaatcgatg aaatatttga aagcaaagtg cggcaacatg
    11701 caggagaaac cgtccctgca caaggtctgt ttttggatga agtttattat cgataaaaat
    11761 actttgataa tggatgaaac gcatgtttca cagtataaat atcgatgtta aataatgtat
    11821 gaagcaaatt aaagaaatat aaaaaaagac tttttagcct gtttatgtgt acagctaaaa
    11881 agtctttctt aaataaaaat ctagtgagaa tgttgtactt ctcttctcgg ttgtttttgt
    11941 ttagaaaaag taaatcgata aagtaaaaat aaaatcaaag taacgataga taaatatctt
    12001 gaagcaattg ctagttttgt gtactgataa gtaataacga ctttatttat acctggagga
    12061 atagttaatt cagttgtgcc aaacttagat aattttgttt gtactagttt gccattaata
    12121 gaagccactt gccctttata acgataaata ggtgtcgtca agacagtatt tttattattc
    12181 gaattatcta attcaattgt aagtttgtta ctcataaaat gagttgttgg atttatttcc
    12241 tggttaccta gtaaatattg atcattatta atcatatcag gatgatagat tgactctttg
    12301 tttgcataat cagtatgatt gtaattttca gctatagcaa cagcgtcttc aggtgctata
    12361 agtgttaatg aatctttgtt agcatggata gaattgctta ctcctgagag atgcaatatt
    12421 agtgcaagaa acgtaaagac cattattttc catgaattat ttttagtaga aaaaatataa
    12481 tagatcacta tactcatcgt ataggctata aataaagaag aaaaaccatt taaccgccag
    12541 acaaattgta gactcttaac tggtgtatgg ttaaaaagtt gccaaggaaa taaattggtt
    12601 gaacaaaaaa gaacaaatac accaagaaag aaaataaata aatcatcagc agttaatttt
    12661 tttataaaaa taaaagcacc aatcaatccg agaaataaga ataatccaat agtatagttg
    12721 ttatagttat tatttaaaat atgtgtcagc atatcactag gagccatacc acttaattct
    12781 tttcccagtg ggactttcaa ttcttgtgct ctagattgtt gaataaaagg aattaagaat
    12841 cccgcactta aaaaaaaggt gaggacggta gcttttaaaa gacttaagag tctagcgatt
    12901 ttttggtccc aaaaataaaa agaaagaaac aacgttcctc caataaatac agaaaccata
    12961 gcgacagaaa gtaaatgagt atacactact agcgtcatgc caatagacaa ccagtaccat
    13021 ttttggtaat ctctaatata aatttcgtaa caccccatta gtatcaaagg caaaaatgtt
    13081 aaagcgacag cttctcccaa tgaagcacga tggaatatgt caatggcacg ataggcggaa
    13141 aatgtataaa taatcgaaaa taacagcgaa atataacgat tgttttttat ttgtttcata
    13201 gaaaaataag aaacgaccat tgttaaaaaa gtgataaaaa aatagtagat attataactt
    13261 aaaacaagat ttcccatcat tttataaaat aaaaaagctg gataaagagt aagccatgga
    13321 taaaaaatat tcatcattgt tccatgatga tcgaagttat tgaagtttac tggagaactc
    13381 catacattat ctagtcctat gattcgagat aaatgaaagt aagtatcctg attgacacta
    13441 tgatagattc ccttagacat gaatagaggg atgacgtaag caaaacttag aaataacata
    13501 aaaatgatat ctattatttg gttttt
//
LOCUS       DACCVH010000074        13372 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.074, whole genome shotgun sequence.
ACCESSION   DACCVH010000074 DACCVH010000000
VERSION     DACCVH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.074"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(188..1036)
                     /locus_tag="IVV98_002198"
     CDS             complement(188..1036)
                     /locus_tag="IVV98_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7807827.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1200..2102
                     /gene="gnd"
                     /locus_tag="IVV98_002199"
     CDS             1200..2102
                     /gene="gnd"
                     /locus_tag="IVV98_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAP7807828.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2104..3105
                     /locus_tag="IVV98_002200"
     CDS             2104..3105
                     /locus_tag="IVV98_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP7807829.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3102..3386
                     /locus_tag="IVV98_002201"
     CDS             3102..3386
                     /locus_tag="IVV98_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7807830.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3419..4216
                     /locus_tag="IVV98_002202"
     CDS             3419..4216
                     /locus_tag="IVV98_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7807831.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4230..5063
                     /locus_tag="IVV98_002203"
     CDS             4230..5063
                     /locus_tag="IVV98_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807832.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5081..5938
                     /locus_tag="IVV98_002204"
     CDS             5081..5938
                     /locus_tag="IVV98_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7807833.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5960..6469
                     /locus_tag="IVV98_002205"
     CDS             5960..6469
                     /locus_tag="IVV98_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807834.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6506..6907
                     /locus_tag="IVV98_002206"
     CDS             6506..6907
                     /locus_tag="IVV98_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807835.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7019..7372
                     /locus_tag="IVV98_002207"
     CDS             7019..7372
                     /locus_tag="IVV98_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807836.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7406..7849
                     /locus_tag="IVV98_002208"
     CDS             7406..7849
                     /locus_tag="IVV98_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP7807837.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7866..8951
                     /gene="uxuA"
                     /locus_tag="IVV98_002209"
     CDS             7866..8951
                     /gene="uxuA"
                     /locus_tag="IVV98_002209"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP7807838.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8944..9657
                     /locus_tag="IVV98_002210"
     CDS             8944..9657
                     /locus_tag="IVV98_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7807839.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            10409..10609
                     /locus_tag="IVV98_002211"
     CDS             10409..10609
                     /locus_tag="IVV98_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7807840.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            11177..11740
                     /locus_tag="IVV98_002212"
     CDS             11177..11740
                     /locus_tag="IVV98_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807841.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(11801..12166)
                     /locus_tag="IVV98_002213"
     CDS             complement(11801..12166)
                     /locus_tag="IVV98_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807842.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12242..12487)
                     /locus_tag="IVV98_002214"
     CDS             complement(12242..12487)
                     /locus_tag="IVV98_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807843.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(12557..12811)
                     /locus_tag="IVV98_002215"
     CDS             complement(12557..12811)
                     /locus_tag="IVV98_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807844.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(12975..13298)
                     /locus_tag="IVV98_002216"
     CDS             complement(12975..13298)
                     /locus_tag="IVV98_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807845.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT         4570 a         2114 c         2792 g         3896 t
ORIGIN      
        1 gttatcgcat ctaacaagta actcgaataa taccaataca accttctcca aagatgcgat
       61 gacatacgtt ctaacccacc gactattgat gttctgtacc acccttgcag aaccaaaaaa
      121 gccactacca aatatttggt agtggctttt tttgttttat ggatttttcg ctttttctgt
      181 tatggtgcta ttctttgatt tcagaaatag tatgtcgaac tttagcgata gaacgacgtg
      241 attctttttc gttgtaaaac atcaaaatca catatagaga gtccaaaatg cttagttgag
      301 aaatacggga agctaaagct tcagatcgga attctgtttc ttcagaaata gaaataaaaa
      361 cgacatcgcc aagtttagca agggaagaat tagcttggct agtaataacg attgtttttg
      421 ctccagtttt tcttacggtt tcagcaatat ggattgtttc ttttgattgc cctgtgtgag
      481 aaatcaaaac agcacagtct ttttccgtca ataaagaagc ttccatcaat tgaatatggt
      541 aatccgtgct gtgagaagtt gcgatagggg aacgcaaaaa tttatgataa gcgtcagttg
      601 ctacaatctc tgaaccgcca acaccgaaaa aatagacacg tttagattca ttgataatag
      661 tagccgcttt ttttagatcc ttttgttgta acaacttttt tgtgtcattt aaagttgaaa
      721 tactagactc gaacaccttt tgcgccatag tgagctcagt atctgttttc tgaatatttt
      781 cgtggataga aatagcagat agatcatttt cttggatcaa catggccatt ttaaaatctt
      841 taaatccatt ataaccaagt ttttttgtaa attgaaaaaa agtagagtca gcaatgccca
      901 gttcacttgc taaattgcta ataggactat gacttacttt gcttggattt tctaaaatat
      961 aatcggcgat agcctgttct tttgggctga agtcgttgta cattgttttg atttgtagtc
     1021 ttatggagac gctcatgaga attcctcatt ttcataataa gattatcatt ttttccgttc
     1081 tcattaatgt taaagataca aggagagtag gaaaaaatca aacaaaaaat atttttgtaa
     1141 aatctattta caaaaaaatt tttttgtata atgagggtat aagaaatgga ggcgctatca
     1201 tggaaattgg tgtaattggt ttgggaaaaa tgggattgaa tttagcttta aacttaaaag
     1261 agcaccatca caaagtacaa ggactcgaca tttcaagtac agctgttagt caggcaagag
     1321 aaaatgacat tcctgcttat caagagatct ctgaatttct agctactttt gagcagaaaa
     1381 aaatcatctg gttaatgctt cctgctggag agataaccga aaacatgtta agaaaacttt
     1441 ttccaaaact cggaccagga gacattatta ttgaaggcgg aaactcttat tataaagatt
     1501 caatccgtcg agcagaagag tttcagaaaa atgaaatcgg ttacttggat tgtgggactt
     1561 ctggaggaat cgaaggagca cgacatcaag cctgcttaat gattggagga gataaagaaa
     1621 cttttctatc cgtggaacaa ttattcaaag atgtagcaat tgaaagagga tatctgtatg
     1681 ctggtgcatc cggaagcgga cacttcttga aaatgatcca taatggaatc gaatatggaa
     1741 tgatgcaagc aatcggtgaa ggattccaac ttgtacaaaa aagtgagtat gcttttgact
     1801 tggaacaagt cgcacgtgtt tggaatcatg gttcggtgat tcgcggctgg ctgatggaaa
     1861 tcatggaaga tcagttaaac gaacatccca atttaagtaa ttatcgggga atcgtttctg
     1921 catcaggtga agcaaaatgg acggttgaaa cagcgctaga aatggctgtt ccagttccag
     1981 taattgcaac tagtttgttc atgaggaatc tttcacagga agaagatagt ttttcagcaa
     2041 aagtagtttc agcactaaga aatgggtttg gcggacatga aatagttgaa aagggtgagt
     2101 aaaatgccag attatcatat agcaatcgtt aattccagca gtttcggaag agtctttcca
     2161 caccacttgg aaagattaaa gtcagttgga gacgttcatt tctttactgt tgatcaagag
     2221 attccaggaa aagaactagc ggagttactt aaaggattca atatcattat tgcaagtgtt
     2281 acgccatttt ttcgacgaga tttttttgaa aacaaagatg aactgctatt gatttcccga
     2341 catggtattg gttacaacaa tattgattta aaagcagcaa aagaacacca gacaatcgta
     2401 tctatcatac ctgctttaat tgaacgaaat gctgtagcag aaaataatat aactaatttg
     2461 ttgtccatgc ttcgacgcac gacacaagca caagcaagag tcaaggacga tcgatgggaa
     2521 gatcgggcgg agttcgtcgg taggacgctg tttaacaaaa cagttggtgt gattggtgca
     2581 ggaaataccg gaagcggagt aatcgaaatt ttgcgtaacg gttttcgctg tgatgttcta
     2641 gcttatgatc cttacaaatc agatttatac atcgaaagct ttggtgcaaa aaaagtagaa
     2701 cttcaagaat tactggaaca atcagatatc atttgtttat gtgcgaattt gacagaagag
     2761 aactatcaca tgatttctga taaagaagtc gatcagatga aagaaaatgt ttatctatct
     2821 aatagtgcaa gaggcgctct agttgatgaa gaagcgatga ttaatggtct gaaaagcgga
     2881 aagatcgcag gatatgccac agatgtttta gaagaagaac cgggacgtca agatcatccg
     2941 tatttagcgt ttgaacaagt agtgattacg ccacatatat cggcctacac aagggaatgt
     3001 ttagaagcaa tgggtgaaaa atgtgtcaga gatgtcgaac agatcagtca gcaccttctt
     3061 cctgaacgtt ctgtccagac aaagagcaac tatataaaag gatgatgaag aaaatggtga
     3121 acggtttaaa agtgaaaaca ggccctcaat tttatttata tgaagaaggt ggtatttcaa
     3181 aagtttctga tctcttgaaa tcatacggcg cgaaaagagt actggtcacc cacggaacgg
     3241 tatcatggga aaaggcgcta cctaaattag tatttttgaa tgacgaaacg attcaatttt
     3301 tttatcatcg ttattctgga gaatgtagtt atgctgaagc cagacgaata gctacaatca
     3361 tcaaaaaaat gaaatcgatt tcgtagttgg cgttggcgga ggaaaactga ccgatctagt
     3421 gggttatagt gccaatcttg caagaatcga tttcggagtc atccctactt tagctagtaa
     3481 ttgtgctcca tggacacctc ttgctgtcat gtataaggag aatggacaag cagaagggaa
     3541 aacagaacac ttttacagac aagctgcttt ttttataaca gatccccaat tagtgattga
     3601 ttcccctgtt ccatatttca ttgccgggtt agcagataca ctagcaaaat ggtatgaatc
     3661 tgagctcatc ttagaacaag attttttgca agatgaatca tttttgaagc tagcacaaga
     3721 tactgcgaag atctgcaaag aagagatttt gaatcattct gctaaagcaa tccaagatat
     3781 ggcacaaaga aaactgacat cggagttcaa acagctttca gagattatct ttgctgttgc
     3841 tggtttagtt ggaggattag gagataaata cgcaagaaat gcggcagcac atgctatgca
     3901 tgacgctatc agtaaatata ttccggaaag ccatcgtttt ctacatggag aaaaagtagc
     3961 gtatgggatt ttctatcaac tggcactaga aggtcgctgg gaaaaaatag acgagttata
     4021 tcctttgtat cgggaattag aactgccggt ttctctagaa caaatgggat tatttccgaa
     4081 agataaacag ataatagata aaatggctga atttattgat tcgaaagaga aagtgcattt
     4141 gattcctata gaggtaacac agaaatcact gatacagtca atgatggaac tggaaggtta
     4201 tatcagaaag atctgaagga ggaggacaca tggaaacatt aagtgtagta caaagtttgt
     4261 tgattgcttt atgggtagcc gcggttatgt cccgctggtt aggtggagga gccacgttga
     4321 ccttacgttt ttctcctttg atgactggat tagtcgtcgg gttgatcatg ggggaagttg
     4381 cacaagcgat gattgttaca gccgctttgc aaatgattta tatgggggtt ttttctccag
     4441 gaggatcaat gccagctgaa ccatctattg cagcagctat cgcagtacca gtcgcattat
     4501 taggggatct gtcgccagaa gcagcgattg ccgttgcggt gccagtcgga ttgctcggaa
     4561 gttacttgta tcagtttcgt tttttcatca atactttttt aggtaaatat acagacaaag
     4621 ctgtagaaga tttgaataca aaagctatgg cccgatcaat tattctttat ccaacggttg
     4681 cctcattttt attattcgtt ccgcttgttt tcattgcttt atatttaggg gcgccattga
     4741 tcgctgatgt aatcaaagct ttagagggaa cagtcgttat ccacattctt gaagtagtag
     4801 gtggagggtt agcggcaatc ggtatcgcga caactgtata cgttatcggt cgaaaagatt
     4861 atctggtctt tttcttcctt gcttatttta tgagtgttgt tttgaaatct ttagatatta
     4921 cgatggttac ttatgccatt tttgggatta ttatcgcttt gatctttgtc cagtcgcaaa
     4981 aagggaaaca agtacagcct gccacaagca ataacaattc agcatctttt gatgacgaag
     5041 atgactatga tgacggattt taatttagga ggaatgggaa atggctgaaa taatggataa
     5101 tcaaacaggt gctcctgaag aaatcacgaa aaaagatgta acaaaagcct atctgagatg
     5161 gcattttgca aacgaaattc ctcactcttt tgaacgttac ttggcgccat cactactata
     5221 cggaatgatg ccaatcttga aaaaacttta taaagatgaa gactctttaa aagcagcata
     5281 taaacggcag ttactgttct tcaacactca attaagctgg ggtggcggtg tgattactgg
     5341 cctaatgtct tctatggaac agcaaagagc agaagaagag tatgaagaaa aagagatctt
     5401 gatgcaggat gacttgatgt ataacacgaa agcgggattg atgggggcac tagcaggaat
     5461 cggagatgca atcgattcag gaaccgtcca atatattttt atcgcaatcg cggtaccttg
     5521 ggcacaacag ggaagtcctt taggcgcact ttttcctttt atctgctttg ggttgtatca
     5581 ggttttacta ggggtatttt tcgcaagaca agctttcact atgggccgta atgctacagg
     5641 cctaatgcaa aacactggtg ttcagacagc gattgaaatg ctatcagttt tagggttgtt
     5701 tatgatgggg gtgcttgcgg gaaactatgt aaaagtagaa tcttcattga aatttgcgat
     5761 atccggacgt gagtttgtta tccaggaaat tcttgatcaa atcgtgccag ggatattacc
     5821 tttagctgtc gtaatgggtg tgtacttgtt ctatacgaaa aaaggattga aagtcacaca
     5881 agcattatta tggctgactg gaatattaat tgtgctagca ggaatcggta ttttataaaa
     5941 agaagggaac gtgaataaga tgggtgtagt caatttagcg cgtgtggatg agcgtttgat
     6001 ccatgggcaa gtaatggtaa cgttatctca aaaaagtgga gtgaattcca tttttgttgt
     6061 agacgaagtt gtagcaaaag ataaatttat gagagatctt tacaaaaatg caggaagccg
     6121 tacaggacaa aaaacaattg tcattacacc agagaaagct aaattctatt gggatgaata
     6181 tcaatttaaa gaatacaatt gtattttgat cgcaaaaaca gtccaaacga tttacgactt
     6241 agtaaaacac ggaatcccca tggaagaatt gaatattgga gggattgctc aaaaaaatcc
     6301 tgatacagat cttttagtga cgaaatctgt ttatttaaat aaatcagatg ctgaaaaatt
     6361 gaaagaaatg aatgaacaat atggcgtaaa gaatatttat tttcaagcca ctccatctgc
     6421 acctaaaaca ggattaaaag atgtattgaa caagtttgat ttgtcataaa caaatgctta
     6481 gaaaaaagat aaagagggcg aaaaaatgaa gaagaacgag ctgtttcgtg attgggaatt
     6541 tcgttatcgc tatatttacc gtaagcgccg tacaaaaaag agtaaacagc gttttctttc
     6601 agcattagta tcagatattt acagtatgag aacagatgtg acagtcattg cttacgatac
     6661 gctagcctac cgatcaaaaa atatttatgt tggagatatc gaaaaagcag agaaagttat
     6721 ctgtacttat tacgatacac ccgttcatgc attaggaagt tatttcatgt ttgattggaa
     6781 agaccaaagg aaaaaaacaa tctactctat attattgtcc ttcattttgt tgttcagttt
     6841 aggttggtgg ggaatgatga tatataacaa aaatcctcat cacgtattcg atctgctatc
     6901 cgtataaaca ggtatcactg tactagcatt tgggagctac tttttcttat tgggaaaagc
     6961 agctcgcgga tggcctagca gacaaacttt tattcgaaat acttcatcca tattaacgat
     7021 gctagaaatg atccgtacga ttgatgatcc gagtgtagcg tatgcgtttg ttgatgaagg
     7081 ctgttatgga gaaaagggct tagacagcgt gagatcgggt atgaaaaaag aggctattct
     7141 tttttatcta gactctgttg gggcagatac accgctacag ttttcgggaa attatttttc
     7201 aaataaagaa cagtggctga aacaagttga taagttgaaa gaaaaaaacg tcaattatat
     7261 ttttagtgca agaaaaaagc aagcgcagtt cttctatttg accaaaacag atttacgagg
     7321 gaaaacattt aattggcaaa atgccaatca gattattgct ctttttcgat aagtaaaaag
     7381 tgcaaaacaa ggagtgagaa gactaatgtt ggaaatcatg atcgttacac atggtaagtt
     7441 gagcgaagga ctgaaagatg cggcggaagt aattgtcggg acatcgagcc atattgaaac
     7501 aatgtgctta gagtctgggg aggacatcca aacattcgga gagaaggtca aagaaaaatt
     7561 aactatgatc aacacagcag aacccatgct agtatttgtt gatctaatta gcgcaagtcc
     7621 gtacaatcaa gcgctcttgg cagtcaatga actgactgaa gaaaagaaag cagccactta
     7681 tgtcataggg ggcgtgaatc tgccaatgtt gttagaagca atcaatcatc agatgcttca
     7741 cacaccgata gaagaagcgg tggaacaaat tgtcaaacaa ggaaaagata atttaactgt
     7801 ttggcatgct tcagcggaag aaaaaaaatt agatgaggac gatttttaga aggaaggctg
     7861 aaaagatgaa gtggggattt agatggtatg gtgaaaaagg ggattcgatc ccattaaaat
     7921 atgttcgcca aataccggga ataaatggga taattggaac tttgctgact aaaatgcctg
     7981 gagatgtttg ggagatttca gaaattgagg agttgaaagc atctgttgag agccaaggac
     8041 tggaactgct tggaattgaa agtgtagcga tccacgatgc aatcaaggca gggacagatg
     8101 aacgagatta ctatattgat aactatatac gaacaatcaa aaacttgtct cgatgtgggg
     8161 ttcgattgat ttgttatagc ttcaaaccaa tttttggatg ggcgaaaact gatttgttta
     8221 atgaaaacaa cgatggaagc tattctcttt tatacgatca gaaaatcgtc gatcagatgg
     8281 agccaggaga aatgtatcaa ttgatacaca gccagtcaaa gggattcaaa ttgccgggtt
     8341 gggaagaaga acggttgaaa aaattcgctc agctggaaaa actgtatgaa ggaatgaccg
     8401 aagaagaatt atttgaaaat ctgacttatt ttttagaaaa agtgattcca gtgtgcgaaa
     8461 aagcagatgt aaaaatggct atccatccag atgatccgcc atgggaactt tttggttttc
     8521 ctagagtgac gaaaaatctt ggcgacttga agaaaattct aaatgcagta gattctccat
     8581 ataatggact aacgctgtgc acaggatctt taggggcaaa tccggaaaac gatttagttg
     8641 aaatcatcca tgaggtaggt tcgcgcatcc attttgtcca cttcagaaac gtggagtttt
     8701 taggagaaag aaagttcaaa gaaacggcac atccctctac agaaggctcc cttgatatgt
     8761 atcatattat gaaagcgttg gtgcaagaag ggttcgacgg tcctatacgc cctgatcatg
     8821 gtagaaccgt gtggggtgaa gtggctatgc ctggatatgg cctgtatgat cgtgcaatgg
     8881 gactcactta catgcaaggt ctatatgagg cgataagtaa ggaaaaacca ctgggagagc
     8941 attatgaata aaatcaagct cttcatcttt gatatggatg gccttttatt agaaactgga
     9001 cgtttagctt atcgtgctta tgtaaaatca gcacaaaagt atgattatga aatgcgtaag
     9061 gaagtctatt atttactaac tggccaaaca gaaatggcga taagagaaca aatgggcatt
     9121 ttgtacggag aagatgttcc atatatcaaa tggcgagaag caatcaatca atataaagaa
     9181 aaaatcgtga aagaagataa gagagtatat acgaaaaaag gagcagaaga aattttatct
     9241 tttgcaaaag aaagaggaat ccatacaatc gtggcttcgt ctaatacacg ggtaaaagta
     9301 gaaatgtatt taaaaatgga aaatctatat gccttgtttg atcaaatcat ttcaggggat
     9361 gatgtaaaaa aaggaaagcc ggaaccagag atctttttga aagcttgttc aaaaatgaat
     9421 attcctccaa gtgaagcact tgtatttgaa gactcgattg cagggatcga agcagcaagg
     9481 cgagcgggca ttttgtcttt tctcatcaaa gatcatttga tagggttgcc cgatcataat
     9541 gggaagcata agttgaaagt agatgtaagt ttatatgaat ccaataaagc agactatgaa
     9601 ttttatgacc tgcatcaagc aaaacgattt ttagaaagta aagggttgta tctctaataa
     9661 agaggactat tttctagtcc tctttattta ttgtcctgca cgactgaggg aacagatgaa
     9721 aaagaagtaa ttttttattt tgaagtatct accttatttg tagtgaacaa tttagaacaa
     9781 acacaaaacg catctactgt tatctaccag tagatgcgtt taaagagaag aacgagaatc
     9841 gtccatatga gggtttccac tccttatgca gattttttta attcttgcac tgcttgttcg
     9901 atcgtaacac ctgtcgctac atgattggta ttttctttgt caaaaacgac aaatagattc
     9961 aaatctgtat ccaaggttac tcgatattgt atatctttgt tatagaatgt catagccatt
    10021 ctcctttctt taaatacttg ctgaaaggca acgaacgcgt tgataacgaa attccattta
    10081 taagtatacc accaattgaa aggttttcat agttaagaaa ttttaaagtc aaaagttgca
    10141 gataaaagca aataaacaag aaaacaaaaa gtgaatcaat cgcggttatt caactttttc
    10201 ttcgattcga agacaataga agacaatgaa ttttatattt cattgcatta tccttgtgtt
    10261 attagaaaaa gcatgatata ttaaatgagt aatctatttt gaaacgtaat ttgagcgata
    10321 tatctacata gataaaactc cttttgccta tcaaatattt attgcaacga aaaaacgtac
    10381 attgatacgt atcaggagga atttatttat gaataacggt acagtaaaat ggttcaacgc
    10441 agacaaaggt tttggcttta tcactggtga agatggaaat gatgtatttg cacatttttc
    10501 agctatccaa ggtgacggct tcaaaacttt agaagaaggc caagcagtgt cttacgatgt
    10561 tgaagatggt caacgtggcc ctcaagcaac aaacattgtt aaagcttaat aaaaattgac
    10621 ttttaaccgt cttttcgaaa gaaaagacgg tttttttgta cgaaaaaatt cattggtcgt
    10681 tgaatgggct gaatagtagt gtataaaaca attttgtgga gcgtgaagct tttatggtag
    10741 aggaaaatac gaataaagtg atgttgataa aaagattcct atcttgaata tgaatcgaga
    10801 tgtcttgaaa atgaatgagt ttgaccaatc attatcctat cgaaatttac agtttcgttc
    10861 gattggtctg tcaattaatg aaaaagtaaa aaagaatatg ttctaggaag agggcggcac
    10921 atctaaattt ttaagtaacg gacagttcaa atatcaagca ttgaaagagg ctatcctact
    10981 gtttgaagga atacgaatat ataaaaacga caaagaggaa aaagtagttc attaaatccc
    11041 ttcaagtgat gaaagaatga gatctaataa aacctgatct ttcatctgtt tttttaataa
    11101 cgtaataatt tttttatttt ttgtgctttc gccgttattg tagagtgatt tagcattctt
    11161 atttttaaaa ataactgtgt tatatattaa aaaaggcata atagttataa gcttttttaa
    11221 agaatattta gaaattatta attttcgtct gaaaacaaaa aaagaaagcg ttattatttt
    11281 agtctatttt caggggggga accttatgat aaaaaaacta tttttactat caatattaac
    11341 gctagcaatg gcaggttgtt ctgactctgg cttagcaact gaactgatca caaaatcaac
    11401 tgaagccacg acagaggagt taaaatgtgg aaacgatcac agtgactaca gaggcttaaa
    11461 tcgacgatgc atgggaatat taggcagaag caattgtaag catcgatgta gtaatcgaag
    11521 aaggtgtaga agaagcaaca gaaaaatcaa aagaaagatc aaaagaagca atctgtgctg
    11581 tgcatcgtat acagacgtcg aagatgcggt acttttaaac cacgtcagga gatgttcatt
    11641 tatgtctagg gaagttggcg atgaaccaaa actagagtac gcttttagtt ttgcacgtga
    11701 ggatgaagat aaccctaaaa cttacgacat tttagcttga tctaagatgg ttaaagcttt
    11761 ttaatgaagt aagaggagat agaaggcttt tctagttata ttaggtaaga taaattcctt
    11821 tttgctccaa atttgctaaa cattctgcta gataaacttc atcgtgttcc ggataaatcg
    11881 gcacgttgcg ctctacagta ggtaaatcaa aaaatgcttc gcatgatttg ccacgataca
    11941 taggattttt ccactctggt gctgggctgt aaccacgttt ttccatttca tccatgacaa
    12001 gctgatgata ttggaataat ctataaggag aatagtgaaa aacataatcc acagtagcat
    12061 gtttctttcc ccagccattt cctcttaatg cacagcattc ccgatgttgt cctaaaagct
    12121 gttgacgagg aagctttgaa atcaattttt catgccataa tcgcatagaa atgtctcctt
    12181 tatatataga ttgttaacct tagacgttaa atgaaaaaac cagcaccaag gctggaaaaa
    12241 atcacttcag tttgcttgct gtttctgagc gaccaattag gtaatcaacg gaaatatcgt
    12301 aaaagtcagc gatatagatt aattcaatga tgcttggaat ttcttctcct tcttcgtact
    12361 tacgatattt gaataaagga atacttaacg cgctagaaac agctacttga gataaagatc
    12421 ggccagttct taagaaattc agacgacaac gtaaagtatc cagtaaaata gcttcttcga
    12481 tactcattta atcacctttc attatagtag aatagttata atgactatag aaagctacac
    12541 atgcaatcaa tagtactcaa tgttttttat ttaaacgtat caaataaaga atgacgatca
    12601 ataaagacaa aaccagtcct gataattctt ctataaaaac actatcgggt tcaaagtagt
    12661 tgtaattaaa aactttccac ataaagtaga tagccggaag agtcaaaata gctaaataaa
    12721 accgttcttt gttccaattc ataagataaa caatacttgc gaccagtgcg accgcaggca
    12781 cccaaaacaa aactctcacc aacgtaatca tgtaacggac tcctcaacga ttcatataat
    12841 aaaagataac atgttattgc atacatcaca aatgaaatgc taggaaaata aaagaagaat
    12901 agatcaatga aaaatgaaaa agcagaacag ttttctgctg ataagcagga actgttccgc
    12961 tgaatgtgtc ttatctatcg agaaaaaatc aatggattga tatctaagta attcaataca
    13021 tataaaaaga ggacgatcgc attcactaaa aaggaaagaa tgatgatccc atagcgaatg
    13081 gaaacatatt taacaaatac ttttgtttga atacgggcat atctttttcc tttatagctg
    13141 agcatcatga caagaagcaa aagggtaatc acaccttgaa aaatcattcc aataaacaga
    13201 attcctgagg tttgataatt taattggaga aaataagctg ctgccgcaac taaatcgaat
    13261 aaaatcgcaa taaatggcaa aataatcact cctaacattg agaataaata aaagaataac
    13321 attttttcta aaataagcaa ataaaaatta aagtaacaaa atagttatga ca
//
LOCUS       DACCVH010000075        13357 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.075, whole genome shotgun sequence.
ACCESSION   DACCVH010000075 DACCVH010000000
VERSION     DACCVH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.075"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            7..174
                     /locus_tag="IVV98_002217"
     CDS             7..174
                     /locus_tag="IVV98_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP7807846.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(236..2047)
                     /locus_tag="IVV98_002218"
     CDS             complement(236..2047)
                     /locus_tag="IVV98_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP7807847.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2044..2409)
                     /locus_tag="IVV98_002219"
     CDS             complement(2044..2409)
                     /locus_tag="IVV98_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP7807848.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2572..2967)
                     /locus_tag="IVV98_002220"
     CDS             complement(2572..2967)
                     /locus_tag="IVV98_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7807849.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2985..3947)
                     /locus_tag="IVV98_002221"
     CDS             complement(2985..3947)
                     /locus_tag="IVV98_002221"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP7807850.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3947..4159)
                     /locus_tag="IVV98_002222"
     CDS             complement(3947..4159)
                     /locus_tag="IVV98_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP7807851.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4180..4878)
                     /locus_tag="IVV98_002223"
     CDS             complement(4180..4878)
                     /locus_tag="IVV98_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP7807852.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4898..5440)
                     /locus_tag="IVV98_002224"
     CDS             complement(4898..5440)
                     /locus_tag="IVV98_002224"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP7807853.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5572..6576)
                     /locus_tag="IVV98_002225"
     CDS             complement(5572..6576)
                     /locus_tag="IVV98_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP7807854.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6573..7562)
                     /locus_tag="IVV98_002226"
     CDS             complement(6573..7562)
                     /locus_tag="IVV98_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP7807855.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7559..8365)
                     /locus_tag="IVV98_002227"
     CDS             complement(7559..8365)
                     /locus_tag="IVV98_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7807856.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8531..9487
                     /locus_tag="IVV98_002228"
     CDS             8531..9487
                     /locus_tag="IVV98_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7807857.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9564..10082)
                     /locus_tag="IVV98_002229"
     CDS             complement(9564..10082)
                     /locus_tag="IVV98_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7807858.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10170..10319)
                     /gene="rpmG"
                     /locus_tag="IVV98_002230"
     CDS             complement(10170..10319)
                     /gene="rpmG"
                     /locus_tag="IVV98_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7807859.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10547..10993
                     /locus_tag="IVV98_002231"
     CDS             10547..10993
                     /locus_tag="IVV98_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP7807860.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11188..13083)
                     /gene="asnB"
                     /locus_tag="IVV98_002232"
     CDS             complement(11188..13083)
                     /gene="asnB"
                     /locus_tag="IVV98_002232"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP7807861.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4159 a         2832 c         2278 g         4088 t
ORIGIN      
        1 gattcaatga aaaaatttgt atctggaata ttagtaggaa gtctggcaac agccgctgcc
       61 gttgctggtt tggttgcttc tgtgaaaaaa acagtgatcg atccaattga cgaaaaagaa
      121 gcaatgatcg aagaaaaccg taaaaaagca atgcgtaaac gcgtttctcg ttaataatta
      181 tttaaaaata cgcatgaaga ctttctaaaa aacagataag tcatcatgcg tatttttatt
      241 tgtcagtcaa tataagttgt gctattttat ctgcctgtct cagattccat ggatctgtat
      301 aaggtctagc tactgctgca gttagccaat ccacaccttc aacaggtatt ccatagcaat
      361 aaaagtcaga ctggatttcc cctgaagcat caatcacgcg attcgtacct cgctcaacat
      421 ctatagcttc tgaatgataa cttcctgtat tatctgaaaa tgaaaaaggg cgaacaagtt
      481 tgttttcctt caaatttttt atgacaggat tacttgaacg agaaaagctt gtttgtggca
      541 atcgagcttc aatcaaatag cgactgctga tttctttatc ttgtagagaa ataacatagc
      601 ggttgtgctt ttgctgaata tcaaatggcg gttcgatcaa atgaaaaata cccgcatcta
      661 tcagtgctgc taattctttc gtccgaatga ttggcggacc gatcgttaaa aagctattta
      721 gatgagtaaa ccatccccat agtatttctt tgtattcctt agcagaaaaa acgtgccatt
      781 caatagcctg ccggattgga tcacgccagt cttttaatgc atcaaatgtt gaagcaaatg
      841 ctcctgtgca attgcctttt tccgcttctt ttatctgccc ttcaataaat attcggctag
      901 cttctgaaaa gggctcattc tgataggcaa gaggagtttc taaatacgac caatcccatc
      961 tataagggat tagtgctgga tgctttccga gacactcctc tgaagagagg gagagaaaat
     1021 catgctcaaa atttttcttt ggaatcggca agtgatattc ttcgatgatt ttcttgtaat
     1081 aaaacaactc aacgtctttt ttcagatagt caaaaaatgt ttcgccagtc aaaaatcccg
     1141 actgatgcca ttgctccagg ttttcttttg ttagtaaccg tggccatgcc attgctccgc
     1201 cttgcttttg atttcttcct cgagggtaat aagggagccc ccttcttgat ccactgtata
     1261 caatcggttc cttgcctgat ggatgataga ccagttttcc cttttcgttc tcgaagcgcc
     1321 ctcctcttga tactgtaaac aatccgacat aatcaaaaaa acttaagcct agacctctta
     1381 aaaagacatt ttctttaggc ggtatcttcg aaagatctac atctgcagga ttagaaggaa
     1441 gctgatacag taaaacattt ttctttgcgt agtctaccca cactctttct tcttctgtct
     1501 catcattttc ccagtgaccg cttgctaaaa caagctgatc gatagaatag ctttgctgat
     1561 ctgtctgtaa aagataacca tcttttcttt tgcttacttt ttttactaaa gaataaacaa
     1621 actgaataga agctggaaat tcttcttgca actttgagaa aaaccagcgt tgatagagtc
     1681 cgtataaaca tcgagtagat tgctgatctt tttccagacg attgatttct tctataatta
     1741 gttgcttatt tttggttacc gtctgttcga tataatctgt agcaggtcct ttactccatt
     1801 gaaacaagtt gggtccctgt gttaccaatc ctccactgga caatgtttca tctgtaaaaa
     1861 gcgtcacttg ttgagaaaca gaattcatta ataactccgg tggctgattc aaccgccaaa
     1921 ctcgacctcc aggaccattg ggatcgaaaa gaaaaagttc aagagaatgt ctgtcctgat
     1981 tattatggag aatcctttct gctacactta atcctctagg tccggcacca atgatcccta
     2041 ttttcatttg catgcctcca tttcgataaa ttttttcaat aaaacagcat ggttctgatg
     2101 ttcatttttt gcaccataaa caaaagtaat gactggatgt tctttcataa gttgactgag
     2161 tttaaaaata gcttgcttct tttcttcttc gaaaatcaat tcttgctggt atttctttgc
     2221 aaatgaagca aatcgttctg gtacatggtc aaaagttttg cgtgcttcat tactaggtgc
     2281 aatttctttc aaccacagat ctaactgcgc tttttctttt gaaattcctc gtggccagaa
     2341 tctatccacg agtattctat agccatcctc tttttcagca tcaaggtaaa cacgttttaa
     2401 tttgatcata gttgtttcct tctttctacc ttttcgctta gcttatatat gtagataata
     2461 gcacaaaata aaaaaaatga acggcacaac tatccattgc gccgttcatg tgatcttggt
     2521 caaaatctaa tgattgattc ggtttttaaa gctgtcatac aatcatctgt tttatacttt
     2581 tttacttttg atttttccag accatccgtc atatccaccc ttaagtaaat aaatctcttg
     2641 ataacctgct ttacgtaatt tatttgctgt acggatgctc aaacttttct tttgatcgta
     2701 aatatagaca ggctggtctt ttcgaataga tcctaatgaa tctttcaaaa cagtgtaagg
     2761 gatgtttctt gcacctaaaa tatgcccagc atcaaacaca tctttttcgc gaacatcgat
     2821 tacttgtgct tttctcattc cttctcgaaa ttcttcttct gtcaaagtcg ttgctgaacg
     2881 tttggccatt actcgtagat agacttccca aaggatgatt gcaagcacaa tcaatagcaa
     2941 aatgatatta attacccata aaaccatgta atgcctccgt ttttttaagc aaatttcaag
     3001 gctaatgagg cagcaccaat gacaccagct tcattaccaa gctctgctaa tttgattttt
     3061 gttgattctc ttacttgcgg gaaagtaaat tctttaaaat atttctctac acggctacgt
     3121 aaaaattctc ctgctgccga tactcctcca cctaacacga tacttgacgg atttaatgta
     3181 ttccccaagt ttccgcaagc taaacctaag tagaagcata cgcgatcaac aaccatcaat
     3241 gcaaacggat cgtcttcttg agccatttca aagatatctt tacttgttac ttcttctccg
     3301 ttgtctagca ttgctttcag ttttgaatcc cctgcgtatt cttctgccaa gaaacgacct
     3361 aggcgtacca cacctgtagc gctagataca gtttctaaac atccgcgttt accgcaagta
     3421 cattcgaacc cttcaggatc cacagtgata tgtccgattt ctcctccagc tccgctcacg
     3481 ccgtgaatca aatttccgcc agcaacgata cctccgccaa cacctgttcc tagagtaacg
     3541 aatacaacgt ctggatcgtt ttctccagca cctttccatc gttcacctaa agcagcaaca
     3601 ttcgcgtcat tatcgatagc gaatttgatt cctgttcctg cctcgatcag ttttttcaca
     3661 aattgaactt ctgtccagtt taagttatac gcaccaataa ccgttccagc ttcgctgtcc
     3721 acgcttcctg gggtacccat gccgattccg ataaagtctt cggctttcat attatataaa
     3781 ttcaaacgat gattgattga ttcaatgatt tcaggaacga tatgcttacc atcatccaaa
     3841 atattggtat cgatgctcca tttttgctga atctctcctt ctggtgttaa aattgcaaat
     3901 tttgctgttg ttccacctaa atcaatccca ataatcttct tgtccattac aaatttcctt
     3961 tctttcggct ttcttcaatt cggtgctctc tttttaatat gcgccacgct gtcatgtatg
     4021 tatcatgatc aatcaaacgg ctatcataca gattacgcaa ttcgatagtc attaattcaa
     4081 tgtcatagat gcgtgcaccc acatagataa agatgccaaa ttttttgaac agctgctgta
     4141 catcatataa gctctccatc tttaagcact tccttcatat tatacaagta aaccatattt
     4201 ttttaaaccc agtaaaatac atattacaaa aagaaataca aaaactagtg tagaaagaat
     4261 cctttggtgt atcgaatagc ttgtctgttg tttcggtaga cccaaaacat tccctaacac
     4321 taatccgcca attagcccac cgacatgtcc ccaaacatct acagaggtat ccagaagacc
     4381 aaaaacaaat gtcaacacaa taaataaaag aaaatgtctg actagctgct ggatcgctgg
     4441 gttatgttta aaatgaaacc ctaagataaa caacgcaccg aacaaaccga atatcgaagt
     4501 acttgcacca ccagacagaa cattcgcttc gttaaaagca aagcttgctg tatttcccat
     4561 tatcccgctg aacatataaa tcaagaaaaa acgccaatgg ccatagattg cctcgatttg
     4621 ctgccccata aaatacagta tcagtgagtt cattacgaaa tgcatcagtc caaaatggat
     4681 gaagattggt gtcactaaac gccaccattc attgaagtga acaagataag gaccatacat
     4741 tccggcataa taagggatct caagtcgcgg aaataattcc atcatgagga agaccgctgt
     4801 ctgtatccct aaaaaagcat aggtccataa cggtcgtctt aaccatgcac gcaattttat
     4861 ttgctgttga taattcatga aaacctccca tttcatttta gtcaataaac aattgttgga
     4921 tcttctgatc aaagctctcc ggttgccatt gttcattcaa ttgttcacga aaaacaaggc
     4981 tacatgtttt tttatgaaaa ttatttaaat accggtcgta ataaccaccg ccaaaaccga
     5041 ttcgataacc ggctctattg tagataatac ctggtacaat gaggagatcg atcatctccg
     5101 gcaaatagag cttctctgat tgtggctcaa gaacaccaaa actcgaacgt acaagaacgg
     5161 actgttcatc catttcataa aacgccatct gacgtttcgg caaagtttta ggtacaacta
     5221 ttttcttttg ttctttttct gctcgttgga taaccggctg tgtatccagt tcaaattcat
     5281 tcgataaagt cgtccctatc acttttgctg acttccagta ctcgctggcg aatagctgtt
     5341 tatagattcg ctgttctttt tcctttttct tgccactttt ggccagattt ttcagctttt
     5401 cgattccttt ccggcgtaat cttactttca attggtccaa aaactcaccc ttccttctct
     5461 cataaaatgg tataggaaaa aaagaaaaat agcaatcgaa ctttcaaata aatgcataaa
     5521 tagaataaaa agaagaccta gaaatgattg gccttccttt tttaatgaat ttcaactgtt
     5581 cagcgcgtgt ttttgtctga taaaaagtgc atacagaaaa tatggcgcac caaaaagggc
     5641 aatcaaaatt cctgtaggta cttccccact tggtagaatc actctagcaa ccatatctgc
     5701 actaagcaga aaaatggaac cgaacaaacc gctcagaaca aaggtccagt tattttcttt
     5761 acgtacgact agcttcgcag catgaggagc tagtagtcct acaaaagata aactacctgt
     5821 caccgctaca ctaccgcttg ccaaagcaac agctaacaac aaaaggattt tttgactttt
     5881 agccacgtta aggcctaatc cttgcgcgcg ttcttgacca aatgatagca atacaatcct
     5941 ctgtgcataa agtcctccta gcggaattaa gataaccgcc catggaagca atgcccaaac
     6001 ataaggccag ctcgcacccc agattgatcc cgctaaccat gcattcacaa atccataatt
     6061 ttccttagat aattggatcg tgcatagcaa tgttaatgca gaaaggccgg cattaacggc
     6121 aataccggac aataagattc gattcatacc caaaaagcca tttcgatcat aggccgcaag
     6181 atagacacag caagcagcta aaacaccacc tagaaaggct acaactagca atagaaacgg
     6241 cagcgaatag tgcgaaaaga aacctaaata aagcatcact aaaaatcctg ctccggcatt
     6301 aatgcccaat atactagaat ctgccaattc atttcttgtt actccttgca agatataacc
     6361 agaaacgcca agacaagctc ctgctaataa actgatcagt aatcgaggaa ctcgaaattc
     6421 tctaacaatc agcgccaaag aagatgattc tttccctatg aacgtggcaa aaagctgatc
     6481 caggtaaata aaaggcgtac caatcattaa actacctata gacaggatga caagtacaaa
     6541 aagcaagaaa tagaacgtcc aatatatttt tttcaccgtt gttccctcct tacttgtatc
     6601 agtaaaaacg gaacgccaat caatgcaatg actaatccaa aaggtgtttc aaaaggggga
     6661 ttgatcatcc tcgctgtaaa atccgccaac ataaccaatc caccgccaac taaaaaagag
     6721 acaggtagaa cataacgata gtccgttcca accattccgc gaacaactgg cggaaccaac
     6781 agcccaataa atgaaacagg tccgactaac gaaacggcaa tggctgctaa cactgcaact
     6841 agacagaaaa caatcaaccg cgttcgttta ggatgacttc caagagctaa tgcatgtgtt
     6901 tcactcaaat gaatcaaaga tattgctttt cctaatgaaa aagaaaccaa aacagcaagt
     6961 atatataaag gaaacaatac tgctaattgt ttccatgtga tattggcagc tccgcctaca
     7021 aaccaaaaag caagatcctg ctgcagatta aagaattggg taagtgcttg gctgatagca
     7081 gtaaaaaaag aactaatagc tacgccagct aaaatcagct gtaaaggatt catgcccatt
     7141 ttcgaaaact gcaaaaaacc aaatacgagc aaagttacag caaaagaacc tgccaatgac
     7201 attagaaaca cagaaaaatc agaagcttta ggccaaaaag caaaactaag ggccattgcc
     7261 aacgaagcac ccgcgttgat tcctagtaag cctgaatctg ctaaaggatt tcttgtcact
     7321 ccttgcatca atgcaccgct caatgcaaaa caactcccta caagaaatgc tcccgccaca
     7381 cgaggcaaac gaatatttcg tatgatttgg tgactttgtt ttgatctatc aaaatcaaac
     7441 aacgcctgcc aaaaatctgc tttttccaca gtcgctgcgc catttgaaag agcaacaaaa
     7501 aaaataatca aaagaacaaa acagaccaaa agcaggagtc tatttttctt catagtcctc
     7561 ataattgatc ctcctgctct tttggcaaca aatcataggt tagaaaaact ggtttatttg
     7621 ttcttggaag cgtgacaatc gttgcatcaa tctcaaatat ttttttcata cactcttttg
     7681 tgatcacttc ttcaggtgta ccttctgtga tcaacttacc gtttttcatt gctaataaat
     7741 aatctgaaaa acgtgaagca tgattaatgt catgaatcga catcaagatc gttgtttgtt
     7801 tcatttgatt gatttcagtc aataactgta ggatctctaa ttggtgtgcc ggatctaaaa
     7861 atgttgtcgg ttcatccaag atcaagatat ctgtttcctg agcaagcgcc atagcgatcc
     7921 agacacgctg ggtttgtcca ccagacagcg ttgcgatatc ccgcatacga aatccagcta
     7981 gacctgtagc atccaacgcc cactcaattg cttcatgatc ttgcgtgtcc atgccactga
     8041 acagtttttg ataagggtat cgtccgtaag atactacttc ttctactgtc atacctgtag
     8101 ggtgttcact agtttgtgct aataatgcaa ttttttttgc aagttctttt gaactgtatg
     8161 tagagatatc agagttattg acaatgatct ttcctgattt cacaggtagt atacgggtaa
     8221 aacttttcaa taaagtagat tttccacttc catttggccc aatcaaacta gtgattttcc
     8281 cttcaggaat cgtaacagac atgttttcaa tgattttttt gttttcgtag ccggctgcaa
     8341 tgtcagctgc tcttaatctc gtcatttcac ccatcctttc gctgaaaatc attctcaatt
     8401 atgacgctgt ttcaacattt cgtcaagcgc tactttcata tctatagcca aatgaagcgg
     8461 ttgacagcgt tcgaaatatc aggaataata accaatgaga aagattctca attatgttag
     8521 gaggaaagaa atgaaattaa aaacaaaagt attcacatta tctagcatat tgctgctggc
     8581 tggagtactg agcgcttgct ccccctcttc agataaagaa acagctacaa ctgccaattc
     8641 gacgacttca tccaatagta ctcatacagt cacagataca cttggacata aagtagagat
     8701 tccaaacgcg cccaaacgga tcatcggcag ttacttagaa gactatctga ttgcactagg
     8761 ggaaaaacct atcgcccagt ggactgttgg cagtggttcc attcaagatt atctgcaaga
     8821 tgatttaaag gatgtcccaa cgatttctta tgaccttcct tatgagaaag tgttaagctt
     8881 tgagcctgat ttgctgttga tttcttcttc cgctactgtc gaaggcggga aatacgaaca
     8941 atatagcaaa atcgcgccaa cttatgttgt aaaaaacgga acagatgtca catgggaaga
     9001 acaactaaaa gatgtcggca aagctttggc aaaagaaaaa gaggcagaaa aaatcatttc
     9061 cgattatcaa aaatccatca agaaaactcg agaagaacta gcagataaaa tcgagaacaa
     9121 gacagctgca gtgttgtggg tgaccaacaa ctcagccttt atggtcagca aaaatcggtc
     9181 aagtggaaga atcgtatacg acgatctgga atttggtgtt cctgatctag tggaagaggt
     9241 ctccaaaaaa gccacttctg actggtctgc tgtttcctct gaaaagctag ctgaattaga
     9301 tgctgactac atcatccttg tgaacagtga caaagatgct gccatgttca atgaaccaag
     9361 ctggaagaat ctaaaagcag tgacagacaa tcatgtactg caattcggac ctgaatctag
     9421 ttggctatat aacggaccta ttgccagtca ggaaatggtc aatgatatca aagaaaaact
     9481 aaattgattt taactaaaaa aagcatcttc acgattagtc gtgagatgct ttttttctta
     9541 ttaacaaact agacgcatag attttattct tcttttgaag caaccctatt ttttactctt
     9601 tcccattttt gaaaacgatg ggcatataga ttttcttgat ccgttatccc ctcatactcc
     9661 tctataaggg cgaagtctga aaaatcaata ttcccaatat acgtatcgcc ttcaaacgtg
     9721 ctatcgatca atgttcgcca gatccgacca gtgtaaggaa gaagttcttg aaaaatccga
     9781 ctaccacccg aaacatagat atcttctgag atcgtttgac tatacgacaa aagttcatcg
     9841 atcgaatgca ttacttccgc attttctttc gtgcgaaaat ttggttgcgt tgtcaacacg
     9901 atgatatggc gataaggaag tgaaagatcc cccattcctt cataggtctt tcttcccatc
     9961 actaaaattc gatccattgt atgttcgcga aagaaacgca tatcatttgg caatcgccat
    10021 ggtaacaaac catttttgcc gatcagacca tttttatctt gtgcccacat ggaaataaac
    10081 atattatccg ctccttatga ttttagatgt tttgagataa aaaaagtctc aattctttga
    10141 ccagcaagga attgagaact ttaaaaacat tattttgttt cacggtgcaa agtaactttg
    10201 cgttcgcgtg ggcaatattt ttgtttttcc aaacgatcag gattgttacg tttgtttttg
    10261 cttgttagat agttacgttc tttacaagaa gtacactcta aagtgatgtt tacgcgcatg
    10321 tttttccctc ccatttttac aagaatcctc taagatgact ctcagacttg attatcttac
    10381 catgattttt tctagattgc tagtgttttt cacgattttg ttaagtaaaa ctacttgacg
    10441 ataaatacaa cggttttact tctcaaacaa aatctttttc tttttgtata aataccctta
    10501 cacttgttta tatagattat gttttttaat aaagggggat actaatatgc catggaacat
    10561 gaaggacttt cctgcatcaa tgaaaaactt agataaattg acaagaaaaa aagcaatcga
    10621 catcgcaaat gcattattag atgaagggta ccctgataac cgtgcgatcc caattgccat
    10681 tgatcaagca aaaaaatggt atgaagatgc tagtgaatca gaaaaacgaa ctttcgaaaa
    10741 agaaaaaaat ccaagcaaga cggatgaaca cgatacgaat cctcgtgctg gaaaactgct
    10801 tgattcagat gtgatcgtag aatatgagga agaacaatgg atcgtgaaat ctaaaggggc
    10861 aaaaaaggca agcaaccatt ttgatacaaa aaaagaagca atcgaaaaag gaaagcaagt
    10921 agcacaaaac aaagaatcaa ctttgttcat ttataaaaaa gatgggacaa aagaaaaaga
    10981 aatcgattat tgaacatatg taaaggggtt gtgacgaaaa tcgtgtcaca acccccttat
    11041 gttcgaaaca atggtgttcc tctgccaact ccgaaccata agtcataata tctataaaac
    11101 gggaagagct gttttttgaa attgtttctt atcactcagt gttaaacggt aggagaaaac
    11161 ctctttttta ttgatatttg attttcatca aacagtcaca tagtcgattg cttctgcttg
    11221 cggaatcgtt tcatctacaa agtagacttt ataccatgtc aagaaactga agattgtcca
    11281 gatttttctt tgctcttctt tacgtccttc gtgatggtca tctagcaact tcatgatttt
    11341 ttcttgatca aaaaattctt ttgcaaaatc tgcttcgaat aatgctttga cttgttcgta
    11401 gccgtgttct tctttcaacc aagctttgat tggcacaggg aatcctaatt tcacacgatt
    11461 cgaccattct tccggaagat gtttgttcgc agcttgtctg aaaatatctt ttgtgttgtt
    11521 ttgattcaat aaaaacttac ttggtatttg ttgagccaat ttcatgactt cgatatccaa
    11581 taaaggtact cggacttcca aagaacttgc catagaaagt ttatctgcct ttaacaagat
    11641 atcttttggc atccattgat gaagatcgac atattgcatc ttattgactt catctttgat
    11701 tccttctgtt ttctcgtaat gaacagtcat gatttcatcc acagatggtg ctgtttgata
    11761 ttttggtgtt aacacttctg atgcttctga ttcttcgaac actcgagcat gaccgataaa
    11821 atattctttt gcaggagcaa gtgattcata taaatggatc cgtccatgga agtttttcat
    11881 ttttccgatt ttacgtccta aattatagcg tgttcctttt ggtaattttt tcaatccttg
    11941 agcaatcaca cggatgaatt ttgaattcgt atggaatcca tacgtttggt atcccgcaaa
    12001 cagttcatcc gccccttctc cagattggac tacccgcaca ctttgtgaag caagatttgc
    12061 taaaaagtac aaaggtacgc aagaaggatt tgaatcaggt tcatctaagt gatactggat
    12121 caaagggaat gctttgaacg acatgtctcc gtcgatcact gctgctgtat tatctaagtc
    12181 caatagttcg gttagttttc tggcttcaat cgcttcatta taggttttat catcaaaccc
    12241 gattgagaaa gaatgatctg gtttcaatac agaggttaca taactggaat caaccccgct
    12301 ggataagaaa gaaccaactt ctacatcact gaccgtatgt gcttcaatag aagcttgaac
    12361 ggtttcgtcg attttttcga tccattcttg tcgggaatgc gtttcttttg tttcaaaatc
    12421 tgcatcccaa tattgctgaa tgtctatttt tccatcttta tacgtataat aatggccttc
    12481 aggcaaacga tagacatctt tgaagaatgt ttcgccgttt aatggagaat attggaaagt
    12541 catataaggt ttcaacgctt ctttgttcaa ttctttgtta aaatcaggat gaggcagaaa
    12601 acttttgatt tctgaaccaa acataaatgt tccgttcatt tctgcataat aatatggttt
    12661 gatcccaaag tggtctcttg caccgaataa ctcattcttt tcattatccc aaatagcaaa
    12721 agcaaacatt ccgcggatct tttgcaataa ttctgttccc cattcttcgt aaccatgcaa
    12781 aaggacttct gtatctgcat gtgtttgaaa aacgtggcca gctgcaatca attcttctct
    12841 caaaggctgg taattataga tttcgccatt aaaaataatg atctttgtcc gatcttcatt
    12901 gtaaataggc tgagtaccgc cctctaagtc aataatactt aatcttctga atcctaaagc
    12961 aacatgttta tcgatatatt ctcctgaact attaggtcca cggtgaacga ttcgatccat
    13021 cattgtatta ataattgttt ttttgttgtc cttgtcgtta acaaaaccta caataccgca
    13081 catttaactt tcacatccta atataaaatt actgtttatt tcattcatat gcatcttatc
    13141 atagaataaa tagcggacga atattttctc tcttacaatt tcgtcacgtg aaaacaaaag
    13201 atgaaagttt ctgtttttac agaaaataaa gtcccaatat ctaatttacc atgttttctt
    13261 ttttgaggct accttattct cttcgtgtta aaaaaatatt agtggatgct atttccaaaa
    13321 aaaccagcaa aaaaagacac gacctaaaga tcgtgtc
//
LOCUS       DACCVH010000076        13032 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.076, whole genome shotgun sequence.
ACCESSION   DACCVH010000076 DACCVH010000000
VERSION     DACCVH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.076"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(79..151)
                     /locus_tag="IVV98_002233"
     tRNA            complement(79..151)
                     /locus_tag="IVV98_002233"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(116..118),aa:Lys,seq:ctt)
     gene            532..1101
                     /locus_tag="IVV98_002234"
     CDS             532..1101
                     /locus_tag="IVV98_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP7807862.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1088..1948
                     /locus_tag="IVV98_002235"
     CDS             1088..1948
                     /locus_tag="IVV98_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7807863.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2138..2842
                     /locus_tag="IVV98_002236"
     CDS             2138..2842
                     /locus_tag="IVV98_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7807864.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2847..4682
                     /gene="walK"
                     /locus_tag="IVV98_002237"
     CDS             2847..4682
                     /gene="walK"
                     /locus_tag="IVV98_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP7807865.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4679..5995
                     /locus_tag="IVV98_002238"
     CDS             4679..5995
                     /locus_tag="IVV98_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807866.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5996..6865
                     /locus_tag="IVV98_002239"
     CDS             5996..6865
                     /locus_tag="IVV98_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807867.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6920..7729
                     /locus_tag="IVV98_002240"
     CDS             6920..7729
                     /locus_tag="IVV98_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7807868.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7832..8461)
                     /locus_tag="IVV98_002241"
     CDS             complement(7832..8461)
                     /locus_tag="IVV98_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAP7807869.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8631..9923
                     /locus_tag="IVV98_002242"
     CDS             8631..9923
                     /locus_tag="IVV98_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807870.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9999..10661)
                     /locus_tag="IVV98_002243"
     CDS             complement(9999..10661)
                     /locus_tag="IVV98_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7807871.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10886..11170
                     /locus_tag="IVV98_002244"
     CDS             10886..11170
                     /locus_tag="IVV98_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP7807872.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11221..12846
                     /gene="groL"
                     /locus_tag="IVV98_002245"
     CDS             11221..12846
                     /gene="groL"
                     /locus_tag="IVV98_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP7807873.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4334 a         2252 c         2819 g         3627 t
ORIGIN      
        1 aataaaaaaa gaacagcgta aatgttttcg aaatgctttc gcaccaacat ttacctgttc
       61 cgtgggtttg gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc tgattaagag
      121 tcagctgctc taccaactga gctaacggcc cgtacaaaaa gtacttaata atagtagcac
      181 taagaatttt aaaatgcaag actacattta aagaaaatca gaaaaatctt tacttcctta
      241 taggaaatca ttcatagatt attcacattt gctcgctatt atataagcat accaacaaac
      301 aaagttcttg caagagaaca aaccctaaca cttttttcat tttttactcc tttcccgccg
      361 tctccccggc gggtctcctg ttcttaacga taaaagacaa gaaggcttag ccttcttgtt
      421 ttttgttttc atggaatccc gctaatcaaa tcacctagtt aaagcaacta gattgaatgt
      481 ttatcataag tctgatatca tgtttatgaa atgaaaaaag gagcggttat gatggaaaaa
      541 atgcgtcagc aattaatgga gtgggggaag gaactagaaa cattccgtct gcctcactgg
      601 gaagaactcc ctgacttaga actttatatg gaccaagtca gaacgttagt tgatcgttat
      661 ctttcacctg tgatacaagg agaaaagcat ccattgctta cctcttctat ggtaaacaat
      721 tacgttaaac taggtttgat accagcacca gttaaaaaaa gatataacaa agaacacgta
      781 gcatttttac ttgcaatcac tacgttgaaa caagtattga ctattcctga aatcaaagaa
      841 gggatattgt tccaaggaaa aacagtagga attcgtgaag cctataatct attttgcgat
      901 gaacaagaag cagctgtgtg gatggtcagc caattagcac aaggtaaatc tcatccgcaa
      961 aaattcgacc aggcaacccc tgtagaatat attgctgtaa gagcggcaac tttatcgttt
     1021 gcaatgaaac ttcttgcgga aaaaacgatt gttctagaaa ccgaatattt aaaagaggag
     1081 aaaacaaatg aaaaacaata aaatcgcaat tttagtagat tcaggtacgg atgtgccaga
     1141 agaattgata aaaaaatacg agatgtatat gatcccattg aaaattattt ataaagatca
     1201 ggtatataca gataaaattg acattacctc tgaagagatc tatcaacgtt tgccagagga
     1261 aatccctggt acatctttgc cggatggtga gtcgatcaca gaaatctttg agcaaatcaa
     1321 aaaagacggt tatgaaaagg tacttgcggt aacaatttcc agtggattga gcgggacata
     1381 taatgtggtt cgtttaattg cacaacagca agaagaattg gaagcatatg tactagatac
     1441 gaaaaatatt ggtattggtg caggtttttc tgcgatccaa gcagcaaaat ggctggaaga
     1501 aggagtagaa tgggatcaac tgatcagtaa tctgaatgag ttagtcgaaa gaacaaaagt
     1561 tttctttaat gttgcgacat tggaatatct tcaaaaaggt ggacggatcg gtttagttgc
     1621 ttctattgta ggaaccgctt taaagcttaa cccaatcatc tcatgtaatg aagaagggat
     1681 ttattacaca gtaggaaaag ctaggggacg taaaaaaagt ttggataaaa cggttgctta
     1741 cgtcaaagaa aaaatcggta atgcaaaggt cttcaactta gctgttgccc atggggatgc
     1801 gaaagaagaa gcaattgaaa tggaagcgag acttaaaaga gagttcccac aagcaaacca
     1861 aatctacttt ggccagattt ctccggcatt agtagtccac actggtccgg gattattggg
     1921 tgtcggtgta caagttttag aaggataaat caaaaaaagg aaacactgag gtgaaaatca
     1981 gtgttttcct tttttattga agttagaaca aaaaataata aagtattttg cactttcatt
     2041 ttaattttct cttttgtttt ataggcaaag atgaaacaaa agcagaaata cggtataatg
     2101 agaaggtatg acaataatat ataagaggtg gctctttatg aaaaaagttt tagttgtcga
     2161 tgatgagaag ccgatttcgg atatcgtcaa attcaattta gccaaagaag gctatgatgt
     2221 ttatactgca tatgatgggg aagaagcctt ggaaaaagtt gctgaggtag aacctgattt
     2281 gattttactt gatttgatgc tacctaaaat ggacggctta gaagttgctc gtgaggtacg
     2341 caaaacttat gatatgccga tcattatggt aacagccaaa gattctgaaa ttgataaagt
     2401 cctaggctta gagttaggcg ccgatgatta cgtgaccaag ccattttcca accgagaatt
     2461 agttgcacgt gtcaaagcaa atcttcgtcg cggtgccacg gctgcgaagg aaccagaaga
     2521 ggcagcacct gcggaattga cgattggtga tttgacgatc catccagaag cttacatggt
     2581 gacgaaacga ggagaaacaa tcgagttaac acatcgtgaa ttcgaactac tcttttactt
     2641 ggcgaagcac cttggacaag tgatgacaag agaacattta ttacaaacgg tttggggtta
     2701 tgattatttt ggagatgtac gaacagtgga tgtaactgta cgtcgtttgc gtgaaaagat
     2761 cgaagataat ccaagccatc caaattattt agtgacacgt cgtggtgtcg gttactattt
     2821 gcgtaaccca gaacaggagt aattggatga aaagaaaagt ccgctttttt cgatcagtca
     2881 attttaagat cgctattacc tttattctga ttttattgat ctcgatcgaa attattggtg
     2941 cctactttat acgtggttta gaacgttcca cgatcaatac atttattaaa gatatgaatc
     3001 aaacggtgga atcattagca acaacaatca gcccggaatt gaatcgaaaa gataatgcag
     3061 atgatgaaga ggtaaatgcg aatatcaaaa gatttattga aaacagtgcg actagcgata
     3121 tcatcgaaat acgggtcgtt gacgaaaaag ggatcatccg aggaacaacc gatgtcaatg
     3181 aacaaagcgc tgtgggaaag aaaaatgatt atgttgatat caatgatttc acgactaaac
     3241 gttatgttgc tttagataac gacgataaac gggtgaatat caatgttcaa ccgatcctgt
     3301 ccccgaccgg cgatgccgtt atcggggctc tttacgtcaa aagtaatatc gaacaaaaat
     3361 attcggaaat caataacaca gcagtcattt tctttactgc ctcactaatt gcggcattta
     3421 tttcaatgat cgtatctgtt ttagttgctc gttcgattac acagccgatc ggtgaaatga
     3481 gagaacaagc cattcgaatc gctagaggag actacagtcg gaaagtcaaa gtgcatggac
     3541 aagatgaact tggacagctg gctgatacct tcaatcagtt agctgaacgt attgaagaag
     3601 ctcaagatac aatggaagct gaacgcaatc gtttggatag cgtgctatcc catatgacag
     3661 acggcgtcat tgcgacagat cgcaggggta aagtcattac gatcaatgat atggctgttt
     3721 ccttgctaga tatcaaaaac gaggaagcaa tcggacaatc gattttgaca cttttagata
     3781 tcgaagaaga atatacgttg cggaaattat tagaagatcc aaacgaaatg gtacttgacc
     3841 gttcaaccag tacattggaa agtgatcaga tgatcttgcg agtagacttt tctatgatcc
     3901 gtcgcgaatc aggttttatc agcggattag tagctgtctt gcatgatgtg acagaacaag
     3961 aaaaaacaga acgggaacgt cgtgaattcg tctctaatgt ttcccatgaa cttcgtacac
     4021 cgttgacaag tatgcgtagt tatatcgaag cattgagcga aggtgcgtgg aaagacgagg
     4081 aagtagcacc aaattttttg aaggtaacgc tagatgaaac agaccgaatg attcgaatga
     4141 tcaatgacct cttaaatcta tctcgcatgg atacaggtaa tacccagctt caattagaat
     4201 atgtcaattt caacgagtta gtgaattttg ttcttgaccg gtttgatatg atggtgggaa
     4261 atcaggaaaa aaattataag atccgtcgtg aatttacgca aagagatctt tgggtcgaag
     4321 tagatacaga taaaatcatc caagtagtcg ataatatcat gaataacgcg atcaagtatt
     4381 caccagatgg gggaacgatt acttgtcgct tattagaaac gcataataac gtggttttaa
     4441 gtatcaccga tcaaggattg gggattccta aaaaagatct gaaccgagtg ttcgagcggt
     4501 tctatcgagt agataaagca cgtgcaagag cacaaggtgg gacaggactt ggattagcta
     4561 tttctagaga agtgattaag gcgcatcgag gcgctatttg ggcagagagc aaggaaggaa
     4621 aagggtcgac tttttatatc tcgctgccat atgaacctta tgaggaggaa tggtgggaat
     4681 gagaatctct gaaaaagtcg ttcgtatagg actcattttg atggttgcgt taagcatata
     4741 cttctcttat gcaatctggc tgagcccagc aggaaaaagt tcaatcaacg tagatgagac
     4801 aaacactcaa atgatcgagt ctcaaagcaa tcgaaaaact tccgaagtct ttcttccgct
     4861 tcatgttaca tggcaccatt cgggaatgat ccaagaaacc aacagtgaaa atctcgtgta
     4921 ccgattgcaa ttgatcatcg ataaagcaag atttggaaag ctttctgaag tagtttcagg
     4981 agacaaatca cagtttgaac aggtgaaaaa tctgaactct ggttttgagt tggcctataa
     5041 tgcgcctttt ttgctaagag aatacaagga agcatttgat ttagatttag atgtgtcgaa
     5101 cttggcaaaa gaaagcgaaa atatgtattt tactagaata caattcgatc aaggaaataa
     5161 aaaaatccga tttttgaatt attcgaacca tctcgtatat gaagcaaata tttcgttgaa
     5221 ttggacagat atcaataaag aattaacagc aaaagacaca aaatggacag aaatgacaac
     5281 agaaccatcg acgatcgaca cgcaatatgc tacgaaacat tcgatcaaac tgaaaaagta
     5341 tagttatatc ctgtcacagc aaccctatac actttttaga aatgcttttt tccagaaacc
     5401 agatagcgtg aaaaataatg atgaaagcaa tgaattgatt ttttacggtg ggaatgaaac
     5461 aatgtctatc cattcggaaa cgcaagtagt tgattttcgt ggagagctgc cagagaaaaa
     5521 agaaaatgct agtgtatttt ctgaaagttt cccctatatt agcaaattag gcagttcttt
     5581 agggaacctc agatattttg accgcagtga caatacgatc gattatcgga tattcgtgga
     5641 aggcttcccg gtttttggga cagacagcag aggacagatt ggtgtggaag ttggcggtga
     5701 aacgaatggt tctgtgcaag tgaatatcca aaccagtttg aatacgattc aagtgccgat
     5761 accttcagac gaagaagtag aacttgcaag tacgaatgaa atcatccagc agttaaaagc
     5821 taagggagca gatagcaaca agattggttc agtgatcgtt ggctatacat ggcaaaatgt
     5881 caaagaaacg aatcgtgtcg ttgatctctt acctgaatgg tatgtgaaat ataaagataa
     5941 ctggtattca gctaacgacc ttctggaaaa attacctgga ttggaggcga attaattgga
     6001 tttcaaaaaa atcgaatgga tatttttcgt cgctttttta gggttgaatg tgtttttatt
     6061 cagcagttat catgacgcgg tataccaaga aaacaatgtc attcgctcta atcagactga
     6121 atcaatccaa caacgtctgg ctagcgacga tatcacttac acggggaaga tttcgtctga
     6181 gaacaagcaa ggctattatc ttagcgcgga gcagaccaat cttagcactt cattagcgaa
     6241 ttatcgcaag gctggtaaaa gcggcttgct ggcaagtggt gtgtttttag acggtgatgt
     6301 tttgacgaaa tctttatcca gttcagatgc tgaaaagaac gtgatcgatc cagataaaat
     6361 tagtagttcc ttggaagatt ttttatctaa caaagacaat attttattcg gtaatgatta
     6421 tgtgtacacg aaaaactttt ctcatttaga agaagaacca ctagaaatcc aagcaagcca
     6481 agagtatgaa ggcatcccat tcaatgatga tacagcaaaa atcgttcttt ctttagaaaa
     6541 aaacgataat gattatagca tcacgaaata catgcagacg catttatctg atatcgagca
     6601 gctgcgcgaa aagacggaac tgtatacgga agaggaagca atcaatacat tgtacatcaa
     6661 taacaaaata ccaagaggat caaaaatttt atggcgtcag ctagcttatt cctgtattct
     6721 gaaagtccgg gaaaaaaatg tgtatgttcc tgtttggcat gtagcgatcg aaacaagcga
     6781 taaagtggtc caaattgaga gtgtcaacgc tttcagcaat acgatcgtga caaacaatac
     6841 tgtaccaaaa gtggaagatc aataaaaaag cgagtataat gaaaaaagtt tacaaagtaa
     6901 gaagggaagt aggagtcaaa tggctgaaga aaaaccagct tttaaaatca gtatcctagc
     6961 aagtggaagt tcgggtaatt cactttatat cgaaagtgaa aaaaaacggc ttttggtcga
     7021 tgcaggactt agcggtaaaa aaatcacttc cttgatggct caaattgatc ggacaccgga
     7081 ccaattagat ggaatacttg tgacgcatga acatcgagat catatacatg gcgtgggtgt
     7141 cttggctcgt aagtatcatt tggatgtttt tgccaatcag cagacttggg aagcgatgga
     7201 accactgatt ggaaatgtac cagtggaaca aaaacatcta tttgagatgg ggaaagtcag
     7261 aacattcggc gatatcgata ttgagagttt cggcgtctcc catgacgcag cggctccgca
     7321 attttatcgt ttccataaag aaaatcggtc attcgtcatg ttgacggaca ccggatattg
     7381 cagtgattat atgcgaggtg tcattgaaaa tgccgatggt tatttgatgg aaagtaatca
     7441 tgatcttgag atgttacgca tgggacctta tccgtggaat ttaaaacagc gtattttagg
     7501 agatagagga catctttcca acgaagacgg tgcacttgtc atgactgatg tgatcggtaa
     7561 tcggaccaaa cgaatctatc ttggccatct tagcaaggaa aacaatatga aagaacttgc
     7621 tcatttaaca atggaaaatg ttttgaaaga aaaagatttt ggcgttggac atgattttga
     7681 aatctatgat acagatccag atgaagcaac tgagctattt tcgatttaaa cagttcaatc
     7741 aataaaaata taaaaagcag aagataaaat caatcagggt tggttttatc ttctattttt
     7801 atttttttag catattaaaa aaataaccgt attatcgact gactacactg atgtgctgct
     7861 tttcatgttt ctcatccagt atctcatcta ctaatgcaat cgcgtaatct gccatgctga
     7921 tcgtactgtc gccagcagcg tttctttgta aataatcatc acttaacaaa taagtacctg
     7981 tacgtttgcc atgtggatca aataaagaag ctggactgat ataagtccaa tgtagatttt
     8041 tagattgttt caattttaac aatccttcgt acatattgaa agctgttgga tagaagggtg
     8101 catttttagg tacttggtca atcatacgag tcgtcttttc tgtatctaag aataacgaag
     8161 aggcaccccc aacgacaatt aagcgtgtat cggttccttc aagcatctca atcaaatggg
     8221 acaaagaagt ttgatgcatt tcttcttttc ctttgggagc gttgaaagca tcaacgacaa
     8281 catcaaaaga tgcaagatca gtagttgtca actcaaataa atccttttgt ataaacggaa
     8341 catctgatgg caatttttct ggatgacgca cgattgccgt cacgtctaaa tctctggaca
     8401 atgcttcgtc taaaataaat gaacctgcat ggccagtagc tccaatgagt gcaattttca
     8461 taaaaaacct ccttttttat tcctgtccat tgtaagcagt tgctgaatat tcgtcaaaga
     8521 atccgatttt tgaaaagctc agtgcgcatt cctttcatgg ttcgtgatca ttgggtatag
     8581 ttaaattaag aaaactgatt gataaaaata gaagttgaag gagataagaa atgaaagagt
     8641 ggttagatcg tgccttttta ccaatgataa catctgttgt gaatcttaga cccttaactg
     8701 ctttgcgtaa tggaatgact tacacgatcc caataattat tgttggctcg ctgtttttct
     8761 tatttgctca ttttcctgtg gattacatcg ctcagtggat agacaaaaca ggattttcta
     8821 tgtattttac acaagtatac caggctacat ttgatgtgat agccttttgg atcgtttttg
     8881 ccattgcata cgcttatgca aaagaagaag acatcgatcg cttaccagtc ggcataacag
     8941 ccttgtctgc ttatctactg cttattcagc cactaaatac tcagatagat actgtctgga
     9001 caggtgctga agggatacta ggagcagtta caactgggct catcatcgga tggggctatg
     9061 cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct gaaaatgttt
     9121 ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg cttatcggtt
     9181 cagcggtttt tcaacagttg ttcagaatga ctgttgttca aggagtatgg acatatgtcc
     9241 agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta ggtttttttg
     9301 ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg ttggttagtc
     9361 ccgtcttgca agcgaattca ttagcgaatg cagaaatctt agcctcagga caagagttga
     9421 cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc atgacggtta
     9481 cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg aaatcgaaga
     9541 aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc aatgaatcaa
     9601 ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt attttcgcac
     9661 cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt cctttattta
     9721 cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta gtaggcggag
     9781 tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt tatttcccat
     9841 ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa aatgatggag
     9901 cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag attgggaaaa
     9961 tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc tttttggaca
    10021 gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat cgatgtccag
    10081 atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa gtagattagc
    10141 agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc tccgacccaa
    10201 aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa ctcttccatg
    10261 atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat catctggatg
    10321 atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc taacatgaca
    10381 gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat aacaatcttt
    10441 ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg cttaaaataa
    10501 aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt gatcaattca
    10561 gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa aattagacca
    10621 tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct ccttttaagg
    10681 gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca taatttcaat
    10741 aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa aaagagggag
    10801 aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta acagattaaa
    10861 aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg tcattatcga
    10921 agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg ctgctaaaga
    10981 gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag aaaacggtga
    11041 aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat acgccggtac
    11101 agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata tcatggcgat
    11161 tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg tgaatcaatc
    11221 atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg cggggtagat
    11281 aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt cgtactagaa
    11341 aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa agaaatcgaa
    11401 ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc atcaaaaaca
    11461 aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc aatcgttcgc
    11521 gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg cgggatcgaa
    11581 ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt tgattcaaaa
    11641 gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg acatttgatt
    11701 gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga atcaaaaggg
    11761 atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta cttatcacaa
    11821 tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata tatcttgatc
    11881 acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca aatcttgcaa
    11941 caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt gccaactctt
    12001 gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc tggtttcggc
    12061 gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac agtaattact
    12121 gacgatctag gtttagaatt gaaagatgta acaatcgaaa acttaggaaa tgcttctaaa
    12181 gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa agaagcaatc
    12241 gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga ttttgaccgc
    12301 gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt taaagttggt
    12361 gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc attgaatgct
    12421 acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct agtgaacgtt
    12481 atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat caagatcgtt
    12541 gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta tgaaggatca
    12601 gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc tgctactgga
    12661 gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac acgttctgcc
    12721 ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt cgttgcagat
    12781 aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat gggcggtatg
    12841 atgtaagaaa aagcaacttg cttatctaca actgatcatt agtgaaagac agataaaaag
    12901 aggctggaac agaagcgttt aactccaaga aataagaaga aattcacgga aattgctttt
    12961 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gctgtttata
    13021 cgtgtttaga gc
//
LOCUS       DACCVH010000077        12926 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.077, whole genome shotgun sequence.
ACCESSION   DACCVH010000077 DACCVH010000000
VERSION     DACCVH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.077"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            133..3660
                     /locus_tag="IVV98_002246"
     CDS             133..3660
                     /locus_tag="IVV98_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP7807874.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="IVV98_002247"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="IVV98_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP7807875.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="IVV98_002248"
     CDS             7448..7789
                     /locus_tag="IVV98_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807876.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="IVV98_002249"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="IVV98_002249"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP7807877.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="IVV98_002250"
     CDS             9146..11566
                     /locus_tag="IVV98_002250"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP7807878.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IVV98_002251"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IVV98_002251"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP7807879.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4393 a         2245 c         2739 g         3549 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaa
//
LOCUS       DACCVH010000078        12867 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.078, whole genome shotgun sequence.
ACCESSION   DACCVH010000078 DACCVH010000000
VERSION     DACCVH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.078"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..269
                     /locus_tag="IVV98_002252"
     CDS             <1..269
                     /locus_tag="IVV98_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807880.1"
                     /translation="LYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRL
                     QHAFDLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            285..962
                     /locus_tag="IVV98_002253"
                     /pseudo
     CDS             285..962
                     /locus_tag="IVV98_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            1474..1770
                     /locus_tag="IVV98_002254"
     CDS             1474..1770
                     /locus_tag="IVV98_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAP7807881.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            1771..2187
                     /locus_tag="IVV98_002255"
     CDS             1771..2187
                     /locus_tag="IVV98_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAP7807882.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            2207..3751
                     /locus_tag="IVV98_002256"
     CDS             2207..3751
                     /locus_tag="IVV98_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807883.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            3894..4118
                     /locus_tag="IVV98_002257"
     CDS             3894..4118
                     /locus_tag="IVV98_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7807884.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4133..5002
                     /locus_tag="IVV98_002258"
     CDS             4133..5002
                     /locus_tag="IVV98_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP7807885.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            4983..5717
                     /locus_tag="IVV98_002259"
     CDS             4983..5717
                     /locus_tag="IVV98_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7807886.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5750..6658
                     /locus_tag="IVV98_002260"
     CDS             5750..6658
                     /locus_tag="IVV98_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAP7807887.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            6655..7197
                     /gene="sat4"
                     /locus_tag="IVV98_002261"
     CDS             6655..7197
                     /gene="sat4"
                     /locus_tag="IVV98_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP7807888.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            7290..8084
                     /locus_tag="IVV98_002262"
                     /note="aph(3')-IIIa"
     CDS             7290..8084
                     /locus_tag="IVV98_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP7807889.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(8192..8380)
                     /locus_tag="IVV98_002263"
                     /pseudo
     CDS             complement(8192..8380)
                     /locus_tag="IVV98_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8360..8932
                     /locus_tag="IVV98_002264"
     CDS             8360..8932
                     /locus_tag="IVV98_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7807890.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            9272..10126
                     /locus_tag="IVV98_002265"
     CDS             9272..10126
                     /locus_tag="IVV98_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7807891.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMIERI
                     IQLENEKE"
     gene            10225..10434
                     /locus_tag="IVV98_002266"
     CDS             10225..10434
                     /locus_tag="IVV98_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP7807892.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            10451..10723
                     /locus_tag="IVV98_002267"
     CDS             10451..10723
                     /locus_tag="IVV98_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP7807893.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            10725..11588
                     /locus_tag="IVV98_002268"
     CDS             10725..11588
                     /locus_tag="IVV98_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAP7807894.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(11851..12588)
                     /gene="erm(B)"
                     /locus_tag="IVV98_002269"
     CDS             complement(11851..12588)
                     /gene="erm(B)"
                     /locus_tag="IVV98_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP7807895.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(12713..12796)
                     /locus_tag="IVV98_002270"
     CDS             complement(12713..12796)
                     /locus_tag="IVV98_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP7807896.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         4566 a         2034 c         2653 g         3614 t
ORIGIN      
        1 aattgtataa gtaccaagcg gaatctgaac gcaaacgaat taaagaacgc caagcccaag
       61 gaattgaaat tgctaagaaa aaaggaaaat tcaaagggcg acaacctaaa ttcaaagaaa
      121 atgatccacg tttacaacac gctttcgatt tatttttgaa tggttgttcc gataaagaag
      181 ttgaagaaca aactggaatt aatcgccgaa cgtttagaag gtatcgatca agatacaacg
      241 tgacagtaga tcaaagaaaa aaacaatgaa aagagggata gttaatgagt acggttattt
      301 tagctgaaaa accaagccag gcattagcct acgcaagtgc tttaaaacaa agcaccaaaa
      361 aagacggtta ttttgagatc aaagacccac tatttacaga tgaaacgttt atcacctttg
      421 gttttgggca tttagtcgaa ttagcagaac caggtcatta taacgaaaag tggcagaact
      481 ggaaacttga atctttgccg atttttcctg atcgatacga ttttgaagtt gcaaaagata
      541 agggaaagca gtttaaaatt gttgctgaac ttctcaaaaa ggcaaataca attattgtcg
      601 caacagatag cgacagagaa ggtgaaaata tcgcctggtc gattatccat aaagcaaatg
      661 ccttttctaa agataaaacg tataaaagat tatggatcaa tagcttagaa aaagatgtga
      721 tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta ctatcccttt tatcaagaag
      781 cgcaaacacg ccaaattgcc gattggttga tcggcatgaa cgcaagccct ttatatacct
      841 tgaatttaca acaaaaaggc gtacaaggta cattttcatt aggacgtgta caaacaccga
      901 ctttatatct catttatcaa cgccaggaag caatagaaaa ctttaaaaaa gaaccttttt
      961 tcctgaataa ttcatagttt tactaatagt ctttcctaac attgatttaa tagtctttaa
     1021 agtattctgc ttcatcaccc attaggtgat gaaaaaagaa cccctttctg atttagcgga
     1081 caaatacttt gacctaatct cagaagatat aaaagaaaaa ataataaaat atccgattta
     1141 tactttgtat aaagaactaa agtagttagc aaatcattta cagcaaatca ctatgttcca
     1201 cataccattt tacatactta ccttatccac gacacatgtt gagatagtat cgaagataaa
     1261 gaaagttgct ccatgttgtt tttgcgagat ggggaaatca aagccacatt gacaaccatg
     1321 atgaataagc ttgctttcag tcataagcta atcctagaac cacttttcaa gtcagttagc
     1381 caaatcgatg aagaaagcga ccgtgaaaga atggacgcta ttgataagct aatggagcaa
     1441 ctattggaag aacgcaatac ccttattgca ctgatgtcca aaggtttcct agaacctgct
     1501 ctttttaatc aggaacgaaa tgttttagat agtgagatta aaaatcttac taccgaaaaa
     1561 acaaacctgg taacgaactc tgcgagtggg gttttgcgag caaacgagat aaaggacctc
     1621 attaattatg tgtcagcaga taattttaat ggtgactaca cggaagaact atttgaagaa
     1681 tttgtagtga acatcattgt aaattccagg gatgagctga cattcaattt gaaatgcggt
     1741 ctttccctga aagaaaaggt ggtgagataa atggcatata ttccatatgg atacaaaatt
     1801 caagatggag tggttactgt cgatgaaaag gcagcaggtc aagtaaaggt attctttgag
     1861 aaatacatat caggactatc ccttacagtg gctggcgaac aggcaggtat tgaaaagaca
     1921 cattctgtga tggggcgcat tttgaaaaac gtcaactacc ttggaaatga tacgtatcca
     1981 gcaattattg ataaagagat atttgataaa gctgaagaag ttagagataa acgtgcaaag
     2041 gatttaggac gagtggtaga gcttgccgct ttcacctctc cccctcccaa agaacgattc
     2101 aaaatgaaaa aggcagataa taagatgcca gtggatcctt ttgaacgagc agaatactta
     2161 tacagtctga tagaaagcga ggaataaagt gacagagaaa aatataatgg ttattcctgc
     2221 tcgtaaaaga gtaggaagta cagccgcaaa agaaaagata aagaaacttc gtgttgctgc
     2281 ctattgccgt gtttctacag aaacagaaga acaaaattct agctatgagg ttcaggtctc
     2341 acactataca gagtttataa agaaaaataa tgaatgggag tttgctggca tctttgcaga
     2401 tgatggtatc tctggtacga acactaaaaa gcgtgacgaa tttaatcgca tgattgcaga
     2461 gtgtatggac ggtaacatcg acatggttat tacaaaatcc atcagccgat ttgcgcgtaa
     2521 caccctagac tgccttcaat acattagaca gctcaaggat aagaacatat cagtttattt
     2581 tgagaaagag aacatcaaca ccacggatgc caaaggtgag gttttgctga ctattatggc
     2641 atctttggca cagcaggaaa gccagagcct ttcacaaaac gttaagcttg ggctacagta
     2701 ccgataccaa caaggaaagg tgcaggtcaa ccataagcga tttatgggct acacgaaaga
     2761 tgaagatgga aatttaacta ttgtccccga agaagctgag attatcaaac gcatctaccg
     2821 agaatacctt gagggtcaga gtctagtggg cattggtcga gcccttgaaa aggatggtat
     2881 tttaacagca gcgggaaaac caagatggcg accagaatca gttaagaaga tacttcaaaa
     2941 cgaaaaatac atcggagatg cccttctgca aaagactgtc acagtagatt ttctgaccaa
     3001 gaaacgagtg aaaaatgaag ggcatgttcc ccaatattat gttgaaaata gccatgaagc
     3061 gattattcct aaagagttat ttttgcaggc gcaagaagaa attcatcgga gaagcaatat
     3121 ctacacagga gaaggcaaga acaaaagaat ttacagtagc aagtacgctt taagtgccat
     3181 caccttctgt ggagattgtg gcgatattta tagacgggtc tattggaata tccacggaag
     3241 aaaagaattt gtctggcgat gcgtgactag aatcgagcaa ggtcctgaag tttgtaagaa
     3301 ccgaaccgta aaagaagatg aactttatgg tgcagtaatg actgcgatta ataagctact
     3361 tgcaggtggg aacaatatga taaagacact ggaagagaat attcatgctg tgattggcga
     3421 aaccacagaa taccaaattt cagagattaa caactcacta gaggaaaaac aaaaagaact
     3481 aatcaagctg gcgaacaagg gtcaagacta tgaccactta gcagatgaga ttgatgagct
     3541 gagagacaag cgacagatcc ttttagtaga agatgcctcc ctcagtggcg agaacgagcg
     3601 aatcaatgag ctgattgaat ttatccgcaa gaacaaattc cgcaccttag aatatgatga
     3661 taagcttgta aggaagataa tccagagcgt tacagtctat gaaggccact tcgtcatagc
     3721 cttcaaatct ggcatcgaaa tggaaatatg aaaaccagaa gtaaatagcc catgactcta
     3781 cagtagagtt gtgggttttc ttttgcttgc tgattataat aatattttaa taactattgt
     3841 gtttatcaac caaatggttt ataatattct tagcgtaaac ttggaggtgc tgtatgacta
     3901 cggcagaaat gattaaagaa ctgtgtgagc aaatgaatat aagtgtttcc gaacttgcta
     3961 gacgtattgg ccagactcca cagaatttca ataaaaaatt acaacgagaa acagtaacct
     4021 tggatgagtt gaaggccatt gctgatgtgc taggtgtcaa gtttgtgcag gcatttattt
     4081 taccagatgg agaagaaata aaaatatcta acgaataaag gaggatgttt atatggtagg
     4141 taatgttatt caaatagtaa cagagaaatt atcatctttg ccttttatag aaggcatcgt
     4201 attagggggc tcacgtgcaa gaggcaccca tacagaaaat tctgatatag atatcggaat
     4261 ctattacaat tcagactcat ttgacctgac agcgattaat caaattgcta cagagttgga
     4321 tgatgagaat agaaacaacc ttgttgtacc tcccggagcg tggggtgatt gggttaatgg
     4381 cggtggatgg ttagttataa acgggtgtca tgttgacttg atattacgtg atataaaacg
     4441 ggtggaacaa ataatcaaag atacggagca aggaattgtt actgccaatt atcagaccgg
     4501 gcatccccat ggttatataa gtgctatgta tcgtggagaa ttagcgatta gtaaaatact
     4561 atatgctaag aacgaaagct tatgcgaatt aaaaaagcag gcagaaattt accctactgc
     4621 tctaaagaaa agcttgatga acttttttat atttgaagct gaattctctt taatgtttgt
     4681 aaaagcaaat gcgggggcag aggataaata ttatattgca ggccatgttt ttcgtattat
     4741 ttcatgctta aatcaagtac tatttgcatg taataatgct tattgcatta acgaaaagaa
     4801 agctataaaa ctgcttgaaa cttttgaata taaacctgaa aaatatgccg aaagagttaa
     4861 tcatattttt gaagtactcg gtctttctct ttttgaatgc tacgacatga ccgagaaact
     4921 ttataaagaa gtgaatgaaa ttgtatcgga gataaataac tttttaaacg aggagagttc
     4981 agatgaaaga aaacaaatat gatgataata tattttttca aaaatacagt caaatgagtc
     5041 gctcgcagaa aggactggct ggtgcgggag aatgggagac tttgaaaaag atgctacctg
     5101 attttaaggg taagcgtgtg cttgatttag gatgcggcta tggatggcac tgtatatatg
     5161 cgatggaaaa cggtgcttcc tctgtagtag gtgttgatat ttctcataaa atgctcgaag
     5221 tagcaaaagg aaaaacccat tttccacaga ttgaatatga atgctgtgcc atagaagatg
     5281 tggatttccc agaggagagc tttgatgtaa tactaagttc gcttgcgttt cattatgtag
     5341 cagactatga gaatttaata aaaaagatat ataggatgct gaaggctggt ggcaatttag
     5401 tttttacagt tgaacatcct gtttttactg ctcatggaac acaagactgg tattataacg
     5461 aaaaaggaga aatactgcat ttcccggtgg acaattatta ttatgagggc aaacggacag
     5521 ctatgttttt ggaagaaaag gttacaaaat atcatagaac actgaccaca tatctaaata
     5581 cactgctttc aaatagtttt ataataaatc agattgtgga gccacagccg ccagagaaca
     5641 tgatggatat tccggggatg gcggatgaaa tgcgacgccc aatgatgctg attgtatcgg
     5701 caaaaaagaa gatgtaataa tatagaaaaa ataaacgagg agtatgtaaa tgagatcaga
     5761 aaaagaaatg atggatttag tactttcttt agcagaacag gatgaacgta ttcgaattgt
     5821 gacccttgag gggtcacgcg caaatattaa tatacctaaa gatgaatttc aggattatga
     5881 tattacatat tttgtaagtg atatagaacc gtttatatct aatgatgact ggcttaatca
     5941 atttgggaat ataataatga tgcaaaagcc ggaggatatg gaattattcc cacctgaaga
     6001 aaagggattt tcctatctta tgctatttga tgattacaat aaaattgatc ttaccttatt
     6061 gcccttggaa gagttagata attacctaaa gggcgataaa ttaataaagg ttctaattga
     6121 taaagattgt agaattaaaa gggacatagt tccgactgat atagattatc atgtaagaaa
     6181 gccaagcgca agggagtatg atgattgctg caatgaattt tggaatgtaa caccttatgt
     6241 tattaaagga ttgtgccgta aggaaatttt atttgctatt gatcatttta atcagattgt
     6301 tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc atcgaaacag gctttaaatt
     6361 aagtgtaggc aagaactata agtttattga aaggtatata tccgaggatt tgtgggagaa
     6421 acttttgtcc acctaccgga tggattccta tgaaaacata tgggaagcat tatttctatg
     6481 ccatcaattg ttcagggcgg tatccggtga ggtggcggaa aggcttcatt atgcctatcc
     6541 ggagtatgat aggaatataa caaaatatac cagggacatg tataaaaaat acactggtaa
     6601 aaccggctgc ctggatagca catatgccgc tgatatagaa gagaggcggg aacagtgatt
     6661 acagaaatga aagcagggca cctgaaagat atcgataaac ccagcgaacc atttgaggtg
     6721 ataggtaaga ttataccgag gtatgaaaac gagaattgga cctttacaga attactctat
     6781 gaagcgccat atttaaaaag ctaccaagac gaagaggatg aagaggatga ggaggcagat
     6841 tgccttgaat atattgacaa tactgataag ataatatatc tttactacca agacgataaa
     6901 tgcgtcggaa aagttaaact gcgaaaaaat tggaaccggt acgcttatat agaagatatc
     6961 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
     7021 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
     7081 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
     7141 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
     7201 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
     7261 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
     7321 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
     7381 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
     7441 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
     7501 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
     7561 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
     7621 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
     7681 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
     7741 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
     7801 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     7861 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     7921 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     7981 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     8041 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     8101 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     8161 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag agttctatat
     8221 tagagatgta aagagttttg gtgaagaggt ttgtgagtat ggcttttata accagggtgc
     8281 aatgagaagc actaacagca gctagcttaa gaacgcatag gatatacttt ttatggaagt
     8341 cacagaggag gaataaaatt tgaacaggat taacagagta acctctattc ttattcagct
     8401 gcaatcaaaa aaaataattc ctgccaaaga aattgcacag cgatttaata taagcttaag
     8461 gacagtttac agagatatcc ggacacttga agaagccgga ataccaattg gatctgaggc
     8521 cggaaaagga tattttcttg tagagggctt cctacttccg ccggtaatgt ttacagcggc
     8581 ggaagtgggt gcattgatta cagcagggaa atttttaaat tgccatggag atgaatcatt
     8641 tataaaggat tttgattcag ctatgtataa aatcaaatct attttgaagc atggtgaaaa
     8701 aaactatgca caggagttgg agaacagtat taacgtgtac agcacatctg gacagaaaaa
     8761 tacattggcg gataacgtta ttgcagcaat tcagactgca atctgcaata aaagggtaat
     8821 atcaattcaa tatcctgcat caggagggca agaaccggaa agcagaatga tagagcctat
     8881 atcactgggg ttttatgaac agaactggta cttaatcggt tttgcaggct aagaaatgaa
     8941 tataggaatt ttcgtgtgga tcggattaaa agcatttgca tagaagaaga gctctgtcaa
     9001 agccatgatg gctctttgga acaaatatta aaacaaatgc tttcatataa aaaactatat
     9061 gccctacaat gccgttgtaa aaattgggga aaagggatat attgatttta tatctttctc
     9121 aaaataaata taaaagccct ttaaagaggg cttttatata ttaatcacaa atcacttatc
     9181 acaaatcaca agtgattaat cacaaatcac ttgtgatttg tgattcttaa tgatacaata
     9241 ttactataca aaaaaagaat ggggcgtagt tatggagaag gaaaaactaa aaatacttga
     9301 agaattaaga cgtattttaa acaataaaaa tgaagcaatt attatcttga ataattactt
     9361 taaaggtggt gttggaaagt ccaaattatc gactatgttt gcttacttga cagacaaatt
     9421 gaatttaaaa gttttaatga tcgataagga cttacaggca acattgacaa aagacttagc
     9481 aaaaactttt gaggtagaat tgccacgtgt caatttttat gaaggcttga aaaatggaaa
     9541 cttggcttct tctattattc atttgactga taatttagac ttgatccctg gcacgtttga
     9601 tttgatgtta ctgccaaaat taactcgctc atggacgttt gaaaatgaaa gtagattgct
     9661 tgctactctt ttagcacctt taaaaagtga ctatgatctt attattattg atactgtacc
     9721 aacgccaagc gtttatacaa ataatgcaat cgtggcgagt gattacgtta tgatcccttt
     9781 acaagcagaa gaagaaagta caaacaacat tcaaaactat atttcctatt tgattgattt
     9841 gcaagaacag tttaaccctg gactagatat gattggtttt gttccttatt tagttgatac
     9901 ggacagcgca acgataaaat caaacctgga agaactgtac aaagaacata aagaggataa
     9961 tttggttttc cgaaatatta tcaagcgaag taataaagta agtacttggt ctaaaaatgg
    10021 cattacagaa cacaaaggct atgacaaaaa agttttgtct atgtatgaga acgtattttt
    10081 tgaaatgatt gagcgaatca ttcaattaga aaatgaaaaa gaatagaatc acaaatcaca
    10141 agtgattaat cacaaatcac ttgtgatttg tgataggtga tgataaaata aatagtaaga
    10201 agaaatagaa agaagtgagc gatcgtggga aatttaggcg cacagaaagc aaaacgaaat
    10261 gatacgccaa tcagcgcaaa aaaagatata atgggggata agacggttcg tgttcgtgcc
    10321 gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt
    10381 atggatcaag ccttagaaga atatatacgg aaatatttac ctgacaaact ttaaaaggag
    10441 tgaaaatgaa atggcagtta cgtatgaaaa aacatttgaa attgaaatca ttaatgagtt
    10501 atcggcaagt gtttataatc gggtattaaa ttatgttttg aatcatgaac tagatactaa
    10561 aaatactcgt ttactagaag tgaatctttt aaatcaatta gaagtggcac aagaagttga
    10621 tttatttcaa caaccatttg aagaattaca agctattcat gagtattggc ggtcaatgaa
    10681 tcaatattca aaacaaattt tgaataaaga gaaagtggct taacatggcg aatattactg
    10741 acttcaccga aaagcaattt gaagatcgtt tagaaaagaa tgttgaacga ctaactaaaa
    10801 atagactagc ggttgaatcg ccaaccgctt ttttacttgg tgggcaacca gggtcaggga
    10861 aaaccagttt gcgatcagca atttttgaag aaacacaagg gaatgttatt gtcattgata
    10921 atgatacctt taaacaacag cacccaaatt ttgacgaatt agtgaaactc tatgaaaaag
    10981 acgtagtaaa acacgttacc ccttattcga atcgcatgac agaagcactt attagccgtt
    11041 taagcgatca aggctataat ttagtgattg aaggaacagg acgaacaaca gacgttccca
    11101 ttcaaacagc cacaatgctt caatctaaag gttatgaaac aaaaatatac gtcatggcag
    11161 taccgaaaat tgaatcatac ttaggaacga ttgaacgata tgaaaccatg tatgcagatg
    11221 atccaatgac agctagggca acaccaaaac aagcgcatga tattgttgtc aaaaacttac
    11281 cgaccaattt agaaaccctt cataaaacgg gcttatttag cgatataagg ctttacaata
    11341 gagaaggagt gaaactctat tcaagcttag aaacgccttc cattagtccg aaagagacct
    11401 tagaaagaga attaaatcgt aaagtatcag ggaaagaaat tcaaccgact ttggagagaa
    11461 tagagcaaaa aatggttcaa aatcaacacc aagaaacccc tgaatttaaa gcaattcaac
    11521 aaaaaatgga aagcttgcag ctacctacac caccaatacc caaaacacct aaacttccag
    11581 gtatttaaac cttaaaaaag gaaaagagta gttaccaaaa aacggtaact actctttttt
    11641 tataaaaaca tttcctcatg ttggggtccc gagcgcctac gaggaatttg tatcgataag
    11701 aaatagattt aaaaatttcg ctgttttttt ctaatttcat tttgaggtga attaattggt
    11761 agttattaga ggtgccctat acctaataat ttatctacat tccctttagt aacgtgtaac
    11821 tttccaaatt tacaaaagcg actcatagaa ttatttcctc ccgttaaata atagataact
    11881 attaaaaata gacaatactt gctcataagt aacggtactt aaattgttta ctttggcgtg
    11941 tttcattgct tgatgaaact gatttttagt aaacagttga cgatattctc gattgaccca
    12001 ttttgaaaca aagtacgtat atagcttcca atatttatct ggaacatctg tggtatggcg
    12061 ggtaagtttt attaagacac tgtttacttt tggtttagga tgaaagcatt ccgctggcag
    12121 cttaagcaat tgctgaatcg agacttgagt gtgcaagagc aaccctagtg ttcggtgaat
    12181 atccaaggta cgcttgtaga atccttcttc aacaatcaga tagatgtcag acgcatggct
    12241 ttcaaaaacc acttttttaa taatttgtgt gcttaaatgg taaggaatat tcccaacaat
    12301 tttatacctc tgtttgttag ggaattgaaa ctgtagaata tcttggtgaa ttaaagtgac
    12361 acgagtgttc agttttaatt tttctgacga taagttgaat agatgactgt ctaattcaat
    12421 agacgttacc tgtttactta ttttagccag tttcgtcgtt aaatgccctt tacctgttcc
    12481 aatttcgtaa acggtatcgg tttcttttaa attcaattgt tttattattt ggttgagtac
    12541 tttttcactc gttaaaaagt tttgagaata ttttatattt ttgttcatgt aatcactcct
    12601 gaagtgatta catctataaa taaatacaga agttaaacga tttgtttgta attttagtta
    12661 tctgtttaaa aagtcataag attagtcact ggtaggaatt aatctaacgt atttatttat
    12721 ctgcgtaatc actgttttta gtctgtttca aaacggtaga tgttttatct acattacgca
    12781 tttggaatac caacatgacg aatccctcct tcttaattac aaatttttag catctaattt
    12841 aacttcaatt cctattatac aaaattt
//
LOCUS       DACCVH010000079        12809 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.079, whole genome shotgun sequence.
ACCESSION   DACCVH010000079 DACCVH010000000
VERSION     DACCVH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.079"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            97..1029
                     /locus_tag="IVV98_002271"
     CDS             97..1029
                     /locus_tag="IVV98_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAP7807897.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1101..2222
                     /locus_tag="IVV98_002272"
     CDS             1101..2222
                     /locus_tag="IVV98_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7807898.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2304..4076)
                     /locus_tag="IVV98_002273"
     CDS             complement(2304..4076)
                     /locus_tag="IVV98_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7807899.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(4079..5791)
                     /locus_tag="IVV98_002274"
     CDS             complement(4079..5791)
                     /locus_tag="IVV98_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7807900.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5906..6574
                     /locus_tag="IVV98_002275"
     CDS             5906..6574
                     /locus_tag="IVV98_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP7807901.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6641..7429)
                     /locus_tag="IVV98_002276"
     CDS             complement(6641..7429)
                     /locus_tag="IVV98_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP7807902.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7512..8984)
                     /locus_tag="IVV98_002277"
     CDS             complement(7512..8984)
                     /locus_tag="IVV98_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807903.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(9114..10307)
                     /locus_tag="IVV98_002278"
     CDS             complement(9114..10307)
                     /locus_tag="IVV98_002278"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP7807904.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            complement(10573..10644)
                     /locus_tag="IVV98_002279"
     tRNA            complement(10573..10644)
                     /locus_tag="IVV98_002279"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10609..10611),aa:Glu,seq:ttc)
     gene            complement(10656..10729)
                     /locus_tag="IVV98_002280"
     tRNA            complement(10656..10729)
                     /locus_tag="IVV98_002280"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10693..10695),aa:Ile,seq:gat)
     gene            complement(10742..10812)
                     /locus_tag="IVV98_002281"
     tRNA            complement(10742..10812)
                     /locus_tag="IVV98_002281"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10778..10780),aa:Gly,seq:tcc)
     gene            complement(10817..10889)
                     /locus_tag="IVV98_002282"
     tRNA            complement(10817..10889)
                     /locus_tag="IVV98_002282"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10854..10856),aa:Phe,seq:gaa)
     gene            complement(10893..10965)
                     /locus_tag="IVV98_002283"
     tRNA            complement(10893..10965)
                     /locus_tag="IVV98_002283"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10930..10932),aa:Asp,seq:gtc)
     gene            complement(10984..11057)
                     /locus_tag="IVV98_002284"
     tRNA            complement(10984..11057)
                     /locus_tag="IVV98_002284"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11021..11023),aa:Met,seq:cat)
     gene            complement(11070..11159)
                     /locus_tag="IVV98_002285"
     tRNA            complement(11070..11159)
                     /locus_tag="IVV98_002285"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11121..11123),aa:Ser,seq:tga)
     gene            complement(11182..11253)
                     /locus_tag="IVV98_002286"
     tRNA            complement(11182..11253)
                     /locus_tag="IVV98_002286"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11218..11220),aa:Glu,seq:ttc)
     gene            complement(11275..11362)
                     /locus_tag="IVV98_002287"
     tRNA            complement(11275..11362)
                     /locus_tag="IVV98_002287"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11326..11328),aa:Ser,seq:gct)
     gene            complement(11387..11460)
                     /locus_tag="IVV98_002288"
     tRNA            complement(11387..11460)
                     /locus_tag="IVV98_002288"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11424..11426),aa:Ile,seq:gat)
     gene            complement(11474..11544)
                     /locus_tag="IVV98_002289"
     tRNA            complement(11474..11544)
                     /locus_tag="IVV98_002289"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11510..11512),aa:Gly,seq:tcc)
     gene            complement(11546..11621)
                     /locus_tag="IVV98_002290"
     tRNA            complement(11546..11621)
                     /locus_tag="IVV98_002290"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11586..11588),aa:Asp,seq:gtc)
     gene            complement(11640..11713)
                     /locus_tag="IVV98_002291"
     tRNA            complement(11640..11713)
                     /locus_tag="IVV98_002291"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11677..11679),aa:Met,seq:cat)
     gene            complement(11726..11815)
                     /locus_tag="IVV98_002292"
     tRNA            complement(11726..11815)
                     /locus_tag="IVV98_002292"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11777..11779),aa:Ser,seq:tga)
     gene            complement(11839..11912)
                     /locus_tag="IVV98_002293"
     tRNA            complement(11839..11912)
                     /locus_tag="IVV98_002293"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11876..11878),aa:Ile,seq:cat)
     gene            complement(11926..11999)
                     /locus_tag="IVV98_002294"
     tRNA            complement(11926..11999)
                     /locus_tag="IVV98_002294"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11963..11965),aa:Met,seq:cat)
     gene            complement(12027..12099)
                     /locus_tag="IVV98_002295"
     tRNA            complement(12027..12099)
                     /locus_tag="IVV98_002295"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12064..12066),aa:Ala,seq:tgc)
     gene            complement(12119..12192)
                     /locus_tag="IVV98_002296"
     tRNA            complement(12119..12192)
                     /locus_tag="IVV98_002296"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12156..12158),aa:Pro,seq:tgg)
     gene            complement(12202..12275)
                     /locus_tag="IVV98_002297"
     tRNA            complement(12202..12275)
                     /locus_tag="IVV98_002297"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12239..12241),aa:Arg,seq:acg)
     gene            complement(12286..12371)
                     /locus_tag="IVV98_002298"
     tRNA            complement(12286..12371)
                     /locus_tag="IVV98_002298"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12335..12337),aa:Leu,seq:taa)
     gene            complement(12388..12459)
                     /locus_tag="IVV98_002299"
     tRNA            complement(12388..12459)
                     /locus_tag="IVV98_002299"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12425..12427),aa:Gly,seq:gcc)
     gene            complement(12471..12543)
                     /locus_tag="IVV98_002300"
     tRNA            complement(12471..12543)
                     /locus_tag="IVV98_002300"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12508..12510),aa:Thr,seq:tgt)
     gene            complement(12561..12642)
                     /locus_tag="IVV98_002301"
     tRNA            complement(12561..12642)
                     /locus_tag="IVV98_002301"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12606..12608),aa:Leu,seq:tag)
     gene            complement(12650..12722)
                     /locus_tag="IVV98_002302"
     tRNA            complement(12650..12722)
                     /locus_tag="IVV98_002302"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12687..12689),aa:Lys,seq:ttt)
     gene            complement(12726..12798)
                     /locus_tag="IVV98_002303"
     tRNA            complement(12726..12798)
                     /locus_tag="IVV98_002303"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12763..12765),aa:Val,seq:tac)
BASE COUNT         4130 a         2730 c         2254 g         3695 t
ORIGIN      
        1 caaaagtatg atgaaacatt aaaaaatgtc tattcttcac ttatcgtttc aaatatagaa
       61 gaaacttcat cttctgaaat aaaaaataag ctttctttgt taaaattaaa agaaaaggaa
      121 tatattattg acgatgctgt ttctgtccct cttattttaa ataaacgaga gaaaaataat
      181 ttaaagaaaa aaatgctcat tccatttgat tcagaagtga aaggattact caataaacta
      241 actatttcta atatagactc gactagggaa aaaatcataa aaatatttga taaaattaat
      301 aatttattca agaatgacaa tgctgaatta aggaagggtc ttttagagtt taaacttcaa
      361 gaactagaac ttcattactc ttatttagtg aaaattaccg aagaaaaaga acaacaaaaa
      421 gcaataaaag aacagatgat agaagaggaa aaagttcgta gagaaattga tcgtgaaaag
      481 aaacgtattg ataaagaaca acgtcaattc aattctgaaa tttccaaatt aatcgcatat
      541 atgcaaaaag ctaatgcaga tgtggaaaaa gaattatatg caaataaaat tcaagaactg
      601 gaagaaaaat taaaagaatt agaagttata cgtgaaaatg tattacaaag agaattaaat
      661 actagagccg gttatgtgta tgtaattagt aatattgggt cttttggtga agacatatat
      721 aaaattggta tgactagaag attagaacct atggatagaa taaaagaatt gagtagtgca
      781 tcggttccat ttgaatttga cgttcatgcg atgatttttt cagaggacgc tccgtctttg
      841 gaaactaaat tgcataatca ttttagaaaa caagaagtta ataaaattaa tcaaagaaaa
      901 gaatttttca aagtttcact agacgaaata gagaaagttg ttttagaaaa ttataatgga
      961 acagtaacat ttacaaaatt agctaaagct gaacaatata gacgatcttt agaattgtca
     1021 aaagattaaa tatataaaaa gccttcgggc tttttctttt aacaattaat aggaacgtat
     1081 attcgaaagg aatagaaata atgtggttag aaaaaataaa tgacaaaaaa tttaagtaca
     1141 ccgaacgtta tacggatccc ttaactgaaa aaaagagaaa agtgtccgtt actttatcta
     1201 gcaattcacg ccaagcttgg aatcaagcta acttactttt gaatgaaaaa atcgcagaaa
     1261 aaataaaacg aaatgaagaa ttaccactaa cttttggaga attaaaaact aaatgggatg
     1321 aaaaatacaa gccaactgta aaagaaagtt cctatcgaac aactcaggtt tatctatcat
     1381 taatttcaaa atatataaaa gatgatgtac ttgtaaaaaa cgttaatagt aatcttatac
     1441 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
     1501 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
     1561 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
     1621 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
     1681 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
     1741 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
     1801 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
     1861 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
     1921 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
     1981 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaaccta gataaaaaag
     2041 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
     2101 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
     2161 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
     2221 aaattgcccc ttttctgccc cttataaaaa caaacaacat aaaatatata aaaagaaccc
     2281 cgttataacg aggttctttt aatttaactt tcaaatacaa attgattatg ataaagttcc
     2341 gcataaaatc cattttctgc taataactcg tgatgactgc cttcttcaat gacttcccca
     2401 tcacgcaaga caacgattct atctgcattc aagattgttt tcagccggtg agcaatcaca
     2461 aagctggttc ttcctttgat tgcttcatcc attgcttttt ggatccttgc ttctgttacc
     2521 gtgtctacat tacttgttgc ttcatccaaa atcaataaag atggatttgt gatgatcgtt
     2581 cgagcaatac tgatcaactg cttttgacct gtactgaata agttattttc ttcggatatc
     2641 tctgtatcat aacctttttc taacgtcatg atgaagtcat gaatattcgc ttgttttgct
     2701 gcattgatga cttcttcatc tgaagcgtcc ggtttgccga atgtgatatt gtctttgatc
     2761 gttccggaga acaatacaga ttcttgcaaa acgattccta catgtctacg taatgcatca
     2821 agatcataat ctcggatatc tattccatcg atgactactg aaccatcatt gacatcgtaa
     2881 aaacggttta gcagattcat gatcgtcgtt ttccccgatc ctgttggacc aacaagagca
     2941 accatttctc ctttgtccac attgatcgag acatctttca agactagttt ttctggagaa
     3001 taaccaaaat ctacgtgctg caacgcaaga cctttttcaa caccatcaaa tgctttacag
     3061 ttttctggtt tgacttcatc tttttcatca aatatttcat tcaatcgtct tgcccctgta
     3121 atcgctaatt ggatcatgct gtatccagat gaaatctgca tcagtggttg gtaatattgt
     3181 tgtgaatact ggacgaatgt cacaactaag cctaatgcca ccgaacgttc caaatcacca
     3241 tttaatgcta accagccgcc gaaaaagata actatcgctg tattgaccag tgacattcct
     3301 tgcatcatcg gaaatagtag accagaataa gcttgtcctt tgaaggttgc ttcgcgaaca
     3361 ctttgattat gctctaagaa tccttcaatc gtttcttctt gtaagccatt tgtgatgatg
     3421 acacgttgtc cgctgatttt ttcatccata taaccattta gtttccccac ttcatcttgc
     3481 tgaagatcca catatttccg tgctttgcgg ataatcaaga cagctatcaa aacggctact
     3541 ggagtggaag caattgtagc ccaagctaac tctacatttt ggcggaacat catgatcaag
     3601 atcccgacaa gtaaaacagc attcgtgatg acttgaagca aagcttggtt caaactattt
     3661 tgaatattat ctaagtcact ggtaaaacga cttaaaattt caccgtcttg atgagaatca
     3721 aagaaacgga tcgtcaattt ttccaatttg ttgaatagac cgatacgcat tcggttcgtt
     3781 gacttcccta ctacttgtgt gaacaaaata ctatagataa agttggctgc actagctagt
     3841 acataaaaca gcaagagttt ccatattaca gaaacaaatt tgcttttatc gtctacgcct
     3901 tgcatcaagc ctcctacgta attagctaat tcttgaaaag cttccccgat gtattgaggt
     3961 gcctttactt gtagataggt agcaatgatc actgtgataa agataaagaa aaaggagagt
     4021 ttgtaccgct tcaaatagtg atagaaaaat ttacttgctt ttattagatc agtcatactt
     4081 actcctccgt tcctttttga gtttcaaaga tttcctgata gacacggttt ccagctacca
     4141 attcctcatg ggttccttcg ccgactaatc tgccttcatc caatactaag atgcggtctg
     4201 ctttgacaac agaagcaatt ttttgtgcga tgacaatcgt cgttgttccc ttcaaatctc
     4261 gatcgagtgc ttctcggacc agcttttcag agcgagcatc cagtgcactc gtactgtcat
     4321 ctaggatcaa gatctttgga ttaccgataa cgccacgagt aatggataaa cgttgctttt
     4381 gaccaccaga aaagttactg ctacgttctt ctattggtgc ttcgtaacga tcagataact
     4441 tttcgatgaa ttcttttgct tgagcaatag aagaagcatg ttccatctct ttttctgttg
     4501 cattcttttt cccttggcgc aagttttgag caatcgttcc tgagaataaa attgcttttt
     4561 gcaaaacaaa ggaaaccgtt tgtcttaaac tcttttcatt tacttgacga agatctacac
     4621 cacctacttc aactttgcct tctgtcggat caaatagacg agggatcaat tgtgctagtg
     4681 ttgacttccc ggcaccagtc gccccgacga taccaaccat ttctccaggt ttgatagaaa
     4741 agctgatatc tttaagcgta tctgtatcct caccaggata acgaaaagaa acatggtcaa
     4801 aagtgacaga acccgtcaac tcttgttctg gaacgtctaa ataagtaaga tctggttcag
     4861 catctaaaat ttccgcaatc cgcttcagcg atacggctgc tcttgaagtc atcatcatca
     4921 tcattccgcc aataatgatt gccatcataa tctgcatcaa gtagttcatg aatgaagcaa
     4981 ttccaccaat taacgtagga tcatctttaa caagatcgct cacaaaaaag atcgccccaa
     5041 ccacagccaa attggcagcc agcatgaagg acgggatcat cacagaaaat aatgtaccga
     5101 ctatgatgtt gtgttttgtt aagtcctcac ttactttgct gaatgacttc aattggtttt
     5161 cttcttgtac aaaagatttc actacacgaa tccctagtaa gttttctttt gcaatgctat
     5221 tcacacgatc aatcagtttt tgaatgatca tgaagtgctt gcccatcctt gtaaatgaaa
     5281 gtgccgtaat cagaaatacc gtaacgataa gcgctacgat gatccaccat aattgcggca
     5341 tcgtgatcat agctaaaatg aaggcaccaa taaataagaa tggaattcga aaaagtgatt
     5401 gcaaagaaat catcactaaa ttttggattt gcgtgatatc atttgttaga cgaacaacaa
     5461 gatttccagc agagaactgt tcgatatttc caaatgaaaa tgtctggatc tttcgaaatg
     5521 cttcttctcg gatatctgca cttacgcctt gagctacttt tgcagagaaa atcgtgttcg
     5581 ttacacctgc ggctaatcct agcaaagcca gactgatcag gtaaatacca attgttttca
     5641 tttcatcatt atcttctgta ataatagctt ccaatacttg ctgtagtaac ttaggttgcc
     5701 ataatgctgc tgcaaccatg actgctacgg acagcaagga aataaaaaca gctactttat
     5761 attttttcgc atgtcgtaag attaatttca ttcgttgatt acaccccttt gtttaaattg
     5821 acaggactaa tttaacactg taaaattaga ccgactaaca atttaccatg tttaaaaaga
     5881 taatgcaata cacgaggttg ataaaatgga aataaagctt tctcaagcaa tcatcattca
     5941 ggccgccttt gatatcctgg ctgaaacaca agctctttcg cagctttcca tgcgaaacat
     6001 cgcaaacaga attcatgttc aagcacctgc tttatattgg tatttcaaaa acaaacaaca
     6061 gctcttgcaa ataatggctg aaacaatgga agaagaatta gcgcttccag atccaacttt
     6121 gccttggaat gaacagttgc tgcagtatat ggaaaattac tatgaccttt atacacgttt
     6181 cccttgtggg gcagaattag aaatcaatac tgtgcccgct tttccgagtc gattagaaca
     6241 tttggagcaa atgatccaat tacttgttcg tgaaggattt tcagtcaccc aaagtcatca
     6301 ggccattgcc tctctccaca atttattgat tggacagtta atggatcagc agcatgaaca
     6361 gcagcttcga caaaaaatta tggacggaaa tgaatttttg aaagaaacag ttctatttat
     6421 gcgtaattat gtagttgaaa atcaattaga gggatttaaa gaaagtatgc agtcccatgc
     6481 agaattgaat gaaaaagcac tctttctaac gagtgcacaa acctatattg aaggcttatg
     6541 ccaacaaaat aaaagaagag aaaacgagca gtaaaaaagc tcctatagag atcactatgt
     6601 ttgtgatctc tataggagct atctttttaa gactcttttt ttatttttct tccattagcc
     6661 acgccaatgc acgttgaatc cattggtccc agaagatcca gttatgatcg ccaggtcctt
     6721 gttcaaaggt gaccgccaag ccttgttcct gcatagcaga taccatttcc tgatttgcct
     6781 gataaagaaa atcagattcc ccacaagcca tataaaatct tggaactggt tttccgcttt
     6841 ttactagttc tttcaataag tattgcggat cattttttga accttcgatt tgatccaatg
     6901 gtccaaagat cccttcccaa aaagatgctt tacgaaccat caaaagatca tccattcgat
     6961 ttcctacaga aacagcgcct gaaagagaga ttactgctgc gaaattttct gattttgcaa
     7021 ggcctagttt taacgcgcca tatccgccca tcgataatcc agcggcatat gttttttctc
     7081 tttttcttgt taattgcggg aataattcat gacaaatctc aggtagctct tctgcaatga
     7141 atgtccaata cttcatgtca taaactgtat ctgtgtacca gccaagatca gtagatggca
     7201 tgatgacagc taatccgtag tttgctacat aacgttcaat cgacgtacgt ctttcccata
     7261 cactatgatt gccacccatt ccatgaagta aatataaaac aggtatatcc gttgtctctt
     7321 gctctgaact ggtgccaatc accttttttg ttgtttgcgg tagtatcaca tttagattga
     7381 cttccatttc taacacattc gaataaatat ttgcttgaat aaatgccata ttttcgcctt
     7441 ccttagtaag aagttatttt tgaataactt taaatttgaa tgattcggct acgtacatat
     7501 cttaaccgaa actactgttt tattttacca cttttttcat gaacgaaaag cgttaagacc
     7561 aaagcaatga tcacgagtaa caagccaact agataaacgg aatgtaaccc atcataaaga
     7621 atttttctta atggtaacaa aatatccgca tcaatatatt tagccgtttg tggattcacc
     7681 agtttattca tgatatctgc atcatttgtt aaatttgctg ctgcaagttc tcgtttagtt
     7741 accccattta tcaataaacc aaaaatagaa accatgactg tttgaccaat tgttcgaact
     7801 aacgtattaa aagaagttgc tacaccaagc tggtcacgag atacactatt ttgtgcactg
     7861 acagtcgagg tagtcatggt cacacctaag cctataccga tgaccgttga tatagcaaaa
     7921 aaccataaat agttacttct gaaaggcata agatacaacc aagcgccccc aatagctgcg
     7981 attagtagtc caattctcaa gacccaatga gttttcattt gagtcatcca cttgcttgca
     8041 aggaaagaac cgaccatcca gactagtgat aatggtgcta ataccagccc accaattgct
     8101 gcattcagcc ctaatacacc ttgcatccac atagggatat aaacatcgat tcccatcaaa
     8161 aaaccactag ccaatgctgc agccaagttg accacaacaa atagtggatt tttgaataaa
     8221 tgcatcatga tgacaggatc tttagctctt ttttcggcaa aaacaaaaat acctaacatt
     8281 acgatactac ctagcagcaa agcagaaaca agcggactca ttccttcgtc tcctaataat
     8341 tggaacccta acagcaatga gacaagcatg gccatcaaac taaaactacc aaaaatatcc
     8401 attggtttag actcatgtat gatttttggt tcatttaaat atagccaaat caaaataatt
     8461 aatagaattc cgatcggcac attgataaaa aagatccagt gccagctgat cgtttcaacg
     8521 atgaatcctc ccgcaagcgg tccaaaaaca ctggcaatcc cccaggctga actattcaaa
     8581 cctaaaactt ttgctcgctt ttcaatagaa taaagatcgc cgatgatcgt caaagctact
     8641 ggcatcattg ccccagcacc catcccttga atcgcacgag cagcaatcaa cccaatcatg
     8701 ctttgagata aaccgcaaaa taacgaaccg ataataaaca ataatgtccc aaaaataaag
     8761 attggtttcc gtcccacttt atccgcaagt tttccgtaaa tcggagtaag catagcgttt
     8821 gtcagcaaat aaatcgaaaa tacccagttc atgatttcca ttccatgtaa tgaaccgaca
     8881 atcgttggca tagcggttgt tacgattgta ccttcaatag ccgtcatgaa cgttgcaatg
     8941 aaaatactca ctgtgaccaa agtaacattt gtttcttttt tcatcttatt cctccctttc
     9001 attatgacag gatctaaaaa tagataaata attactatct ttttcaagag gttaactgcc
     9061 ataaaaaaag ctggaacaac caccacttgg cgatcgttcc agctgaatat aacttatttt
     9121 gctaaacttg ctttcaacgc atctactttg tccgtatgtt cccaaggcaa atctacatct
     9181 gtacgaccaa aatgaccgta agcagctgtt tgtttgtaaa tcggacgacg caaatcaagc
     9241 atctcgatga ttcctgctgg ccgaagatcg aagttttctc tcactgcagc aatcagttct
     9301 tcttccggaa ccgttccagt accgaaagta ttgattgaga tcgaaacagg ttgagcaaca
     9361 ccaatcgcat aagctagctg tacttctgct ttgcgagcaa gccctgctgc aacaatgttt
     9421 ttagcaatat aacgtgcagc atagctggca gaacggtcaa cttttgtcgc atctttacca
     9481 gaaaaagcac cgccaccatg acgagcataa ccgccatacg tatcaacaat gatttttctt
     9541 cctgttaatc cggcatcccc ttgaggacca ccaatgacaa atcggccagt cggattgata
     9601 taatatttcg tttgatcatc taataattca gctggaataa cttccttcac tactttttcg
     9661 atgacatcat gacgaattgt ttcattatct actgcatcat catgctgtgt tgaaataacg
     9721 attgtatcta cgcgttccgg ttgtccttga tcatcatatt caaccgttac ttgagatttt
     9781 gcatctggac gtaaatacgt taattcattt gatttacgca aatctgccaa gcgtcgtacc
     9841 agacgatgac tcaaagcgat tggtaaaggc atcaattctg gtgtttcatc tacagcaaac
     9901 ccaaacatta aaccttggtc accagcacca atctcatcta atacgtcttt tttatcttca
     9961 tcccggatct caagtgcttc atcaactcct tgagcaatat caggagattg ttcatcaatc
    10021 gcaaccaata cagctgctgt atctccatca aatccgaatt ttgcacgtgt ataaccaatt
    10081 tcttttattg tttcccgtac gactttttga atatctacat atgccgtcgt agatatttct
    10141 ccaaatacta aaacaagacc agttgttaca gacgtttcac acgctactcg tgctgttgga
    10201 tcttgtttta aaattgcatc caagattgca tcactgattt ggtcagcaat tttatctgga
    10261 tgtccttcag aaacagattc tgatgtaaat aagtgtcttt ctaccattat aatgattccc
    10321 cctagttaaa ttcggttaca aggcatctcc gtcctgcgga tcctttcggg aacttgcaac
    10381 gaaccaagta tagcagataa aacagttttc tgctcgtatt ttttcatttt tttgcttaaa
    10441 aaatataaaa atattttaca ttagaactgt ccaaaaaagc ttagcacaat catccataaa
    10501 gataactctg ctaagctttt taaaatcatt ctttcagata aaaagaaaaa gatactcaaa
    10561 aagtatcttc catgacccgt acgggattcg aacccgtgtt accgccgtga aagggcggtg
    10621 tcttaaccgc ttgaccaacg ggccaataaa ataaatgggc ctaaatggac tcgaaccatc
    10681 gacctcacgc ttatcaggcg tgcgctctaa ccagctgagc tataggccca taaaaactaa
    10741 aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt tttaccacta
    10801 aactacaccc gcataatggc gcgggacaga atcgaactgc cgacacatgg agcttcaatc
    10861 cattgctcta ccaactgagc taccgagcca aacggttccg acgggaatcg aacccgcgat
    10921 ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg gaaccaatgt ttttagtttt
    10981 taattgcggg agcaggattt gaacctacga ccttcgggtt atgagcccga cgagctacca
    11041 gactgctcca tcccgcgata atatgaaaaa ggaggataag ggattcgaac ccttgcacgg
    11101 ttttacccgc ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca
    11161 tgtaaaacta tattaaatta atgacccgta cgggattcga acccgtgtta ccgccgtgaa
    11221 agggcggtgt cttaaccgct tgaccaacgg gccaggtaaa acaaaatatt gaaacggaga
    11281 aggagggatt tgaaccctcg cgccggtttc ccgacctaca cccttagcag gggcgcctct
    11341 tcagccactt gagtacttcc ccaaaaccaa taagattttg tactaatggg cctaaatgga
    11401 ctcgaaccat cgacctcacg cttatcaggc gtgcgctcta accagctgag ctataggccc
    11461 ataaaaaact aaaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgtg
    11521 gttttaccac taaactacac ccgcatggcg gttccgacgg gaatcgaacc cgcgatctcc
    11581 tgcgtgacag gcaggcatgt taacccctac accacggaac cagtgttttt agtttttaat
    11641 tgcgggagca ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccagact
    11701 gctccatccc gcgataatat gaaaaaggag gataagggat tcgaaccctt gcacggtttt
    11761 acccgcctga cggttttcaa gaccgttccc ttcagccgga cttgggtaat cctccatatg
    11821 aaacttacaa cgccacaatg gaccttgtag gactcgaacc tacgaccgga cggttatgag
    11881 ccgtctgctc taaccaactg agctaaaggt ccaggctctt aaaaatcgcg gcggagggga
    11941 tcgaaccccc gacctcccgg gtatgaaccg gacgctctag ccagctgagc tacaccgcga
    12001 aaaagatatt cattatttaa atgaaatgga gcctagcggg atcgaaccgc tgacctcctg
    12061 cgtgcaaagc aggcgctctc ccagctgagc taaggccccg tgtttaaatt tataattatc
    12121 gggaagacag gattcgaacc tgcgacccct tggtcccaaa ccaagtgctc taccaagctg
    12181 agctacttcc cgtttaatta acgcgcccaa gaggagtcga acccctaacc ttttgatccg
    12241 tagtcaaaca ctctatccag ttgagctatg ggcgcatatt tgaaatgccg aggaccggaa
    12301 tcgaaccggt acggtgatca ctcaccgcag gattttaagt cctgtgcgtc tgccagttcc
    12361 gccaccccgg cgcgattgct ttggcaaagc ggaaaacggg gttcgaaccc gcgaccccca
    12421 ccttggcaag gtggtgctct accactgagc tatttccgcg tgtttaaaga tgccggctaa
    12481 aggacttgaa ccctcgaccc tctgattaca aatcagatgc tctaccaact gagctaagcc
    12541 ggcatgtaaa acttaaatta tgcgggtgaa gggacttgaa cccccacgcc gtaaggcgct
    12601 agatcctaaa tctagtgcgt ctgccaattc cgccacaccc gcaaaaatat gagccgtaca
    12661 gggctcgaac ctgtgaccct ctgattaaaa gtcagatgct ctaccaactg agctaacggc
    12721 tcatatggag gttaacggga tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc
    12781 cagctgagct aaacctccat ggataactt
//
LOCUS       DACCVH010000080        12735 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.080, whole genome shotgun sequence.
ACCESSION   DACCVH010000080 DACCVH010000000
VERSION     DACCVH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.080"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(87..266)
                     /gene="rpmF"
                     /locus_tag="IVV98_002304"
     CDS             complement(87..266)
                     /gene="rpmF"
                     /locus_tag="IVV98_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP7807905.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(324..893)
                     /locus_tag="IVV98_002305"
     CDS             complement(324..893)
                     /locus_tag="IVV98_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP7807906.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1079..1981
                     /locus_tag="IVV98_002306"
     CDS             1079..1981
                     /locus_tag="IVV98_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7807907.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="IVV98_002307"
     CDS             complement(2016..3800)
                     /gene="pyk"
                     /locus_tag="IVV98_002307"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP7807908.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="IVV98_002308"
     CDS             complement(3874..4836)
                     /gene="pfkA"
                     /locus_tag="IVV98_002308"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP7807909.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="IVV98_002309"
     CDS             complement(5004..8318)
                     /gene="dnaE"
                     /locus_tag="IVV98_002309"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP7807910.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8549..8734
                     /locus_tag="IVV98_002310"
     CDS             8549..8734
                     /locus_tag="IVV98_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP7807911.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8796..9992)
                     /locus_tag="IVV98_002311"
     CDS             complement(8796..9992)
                     /locus_tag="IVV98_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7807912.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10162..11598)
                     /locus_tag="IVV98_002312"
     CDS             complement(10162..11598)
                     /locus_tag="IVV98_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP7807913.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11891..12700
                     /locus_tag="IVV98_002313"
     CDS             11891..12700
                     /locus_tag="IVV98_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7807914.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2673 c         2250 g         4010 t
ORIGIN      
        1 atatttttta tttaccgact acaaaaaaat aaacctcaag gctccatggt tagccttgag
       61 gttttacatt ttctaattaa aatgtattaa gcttcttttg acattacgtc cttaccatca
      121 tagtaaccac aatttgcaca tacgtgatgg ctttttttca tttcaccaca gtttggacat
      181 tcgtttaacc ctttgattgt caatttgtag tgtgtacgac gttttgcttt tttagctttt
      241 gatgttcttc tagctggtac tgccattttg ctacacctcc ttgtaaagtc ttgtatctaa
      301 attagacaca atatattcca atcttacttg ttatcgtcgt cttttgattt agaatcaaaa
      361 agttcagata gttttgcaag acgaggatca attttattct cggcttcttc catttttctg
      421 cgctggtatt cttcttcgga aacaacttcc caatcattgc cttttggaag ttctgttgct
      481 gcttcctctt cttttgtcaa tacccgcatt ggaatcgcca ataagatgtt gtcttcaatc
      541 gactctgcta aattcaataa tggaccttca attagcaaaa tctcatctgc agacatttgt
      601 tcatctctac tttggaattg ttcttctgtc atgaatactt cgtctacaga aaaatccatg
      661 ggcagttcaa caggttctag tgaacgtgtt gaaggaactg tcaaagtcgt ctgcacagtg
      721 taatgaacga tatagccttt cttatcaact gagaccaaac cttcgacttc cactggcgca
      781 acatcaagta ttaaattgtc tcgcttcatg agagcggctt tcaagtcgag cgtctcatga
      841 aaagttaacg gtgtctcctg gtattttctc aattccaata aagaccattt catttttcat
      901 cactcctaag caacaaaagc aattatacag ggcaaaaagc atgttgtcaa tgaaattttc
      961 ttgacacctt gcagttcata aaaaaacaga aaaatcttta ttagaaagcc tctgtttgct
     1021 atcatcctca gaatcattta caataatcat tattccatta aaggagcgga tgatcttcat
     1081 gaacacgaaa gatatcgaat actatgtcca aatcgtcaaa caaaaaaatt ttacgaaagt
     1141 ggctaattat ttccgtgtga gccaacctac tattacatat gcattacaac gtcttgaaaa
     1201 agagtttgac accgtactta ttacaagaga tcgatcgcat cacgaattaa tcgtcacgcc
     1261 ttctggaaag cagctgtttc tccatgcaca aaccattctc caagagattt ctactgcaag
     1321 agctgaaatc actcagttgc aaaagaaaaa gcttcgtttt ggcatgcctc ctattatcgg
     1381 caatgaatac tttcctaaac tgtcaagtta ctttatcaag catgaattga tgaatcaaat
     1441 tgagattacc gatggaggct ctcgggactt atacgggatg atccgacaag ggaggatcga
     1501 tttagctgta ttaggctcaa cacagccaat cgtggatcaa tatttagaaa cagagttact
     1561 tttggacaaa cgtttcatga tcgtcgtgcc acctacacat cctctttcca agcaggatac
     1621 tgtctctttc aaagatatag cagatgaaca gtttgtacta ttgaacgaac attatgtcca
     1681 ccccgcagca ttcactaagc tttctaaaca aacacatact catccaaaag ttgtttatca
     1741 aagcaatgac ttgacgattt taaagagtat ggtccgagaa aatgtgggta tcggtttttt
     1801 ggcagagatt gctgtccatc ctgaagatca tttagtttgc ctccctcttt cagatgaagt
     1861 tcagcctcgc ttcttgattt cattggcaaa acgaacacag cagatcgtca cgcctcttca
     1921 agaacaagta gtccaagtta tccatgaatt cgttacagca caaaaaaaca gctcttcgta
     1981 aaagaagagc tgtttttatt ttttattaag ctaaattaga tagctgttgt ttcgccacgg
     2041 taaacgatgc cgcgacgtga atcaacggta atcaattcac cttctgtaat tgttgttgtt
     2101 gcgcctttag caccaacgat tacaggaata tcttgtgcaa ttcctacaac tgcagcgtga
     2161 gaagtcaatc cgccttcttc aacgataaca gcagctgctt tttcgattgc aggcatatat
     2221 tctttgtcag ttgatggtac aactagaacc attccgtctt ttgctttttt tacagcttct
     2281 tcagcagatg aagcaataac tgcatttgca acgacagatt tttgtccaac gccttgagct
     2341 tctaataatt tagaaccaat catttgaatt ttcatcacgt tagttgttcc gcgttcacca
     2401 actggtacac cagcagtgat caagattaaa tcgccttctg atgcgaaacc taattcaaca
     2461 gcttttttag ctgctagttc aaacatttca tcagttgttg atggtttttc agcaactgtt
     2521 gggtaaacgc cccagtttaa catcaaacca cgttttgtgc gttcgtcaaa agtaacagcc
     2581 aagatatctg catctggacg atattttgaa atcatttttg cagtgtatcc tgattcagtt
     2641 gcagcaacga ttgttttcac gcctagattt tttgcagcac gagctacaga taaaccgatt
     2701 gtttcagtta catctgtttt atcgaattcg ttcaattgga atgtacctaa ttctgataat
     2761 gcattttcag cttcttggtc gatacgtgcc attgttgaaa cagcttcaac tgggtagtcc
     2821 ccgtttgcag attcaccaga tagcattgtt gcatctgtgc catcaaatac agcgttagca
     2881 acgtcagaag cttccgcacg tgttggacgt gggttttctt gcattgattc taacatttgt
     2941 gtagcagtga taactgggat accagcagca ttacattttt tgataatgcg tttttgaacc
     3001 attggtacta gttcagctgg gatttcaaca cccatatctc cgcgggcaat cataacaccg
     3061 tcagaaactt tgatgatttc gtcaatgttg tcgatacctt cttgagattc gattttaggg
     3121 aagatttgaa catgagtcat gtctttttct tctaagattt cgcggatatc tagaacgtct
     3181 tgtgctttac gtacaaaact tgcagcgata aagtcgatat cgttgtctaa accaaaacga
     3241 atatcgtcag catcttttgg agtaatacct ggcaaactaa tagaaacgcc tggtgcattt
     3301 acccctttac gtgatcctag catacctgca tttttaactt ctacgactaa ttcacggttt
     3361 gcttcgtctt tttcaatgat ttgcatatcg atcaaaccat catcaaataa aatgtgtccg
     3421 ccaacgtgaa catcgtcaaa taatcctggg taagtaaccg cgattttttc ttttgaacct
     3481 acatgttcag gatccataga gatgcgtgtt tgatctccta cttcaaattt gatgtatcct
     3541 gcacgaccaa aatcagcttc tgttgtgcct tgaacagttg tacggatttc agctcctttt
     3601 gtatctaaaa gaataccgac atcttttcct gtctttttaa ctgcttcacg gaccatagtc
     3661 atacgtgata attgttcttc atggtcacca tgagaaaaat taaagcggaa gacatttgcc
     3721 ccagattcaa tcaattgaga aataatttct actgagttac ttgctggtcc taatgtacta
     3781 acgattttgg tttttttcat ttaaaaaact ctcccattca attttgttta tttaaagctg
     3841 tacacagctt aaatagcttg gtttctttca ctcttaaaat gaaagtgaat tatttagatc
     3901 atatagtgat aagtctggtt tatgtttgtt gttttcaagt gtatcaatga tgtcagacgc
     3961 aacgatttcg ttgtcatgga taccgacaca taatccacct tttccttctt gaagcaattc
     4021 gacagcgtaa gcaccgaatt tacttgccaa cacgcggtcg cgtgcgcttg gtgctccacc
     4081 acggacaacg tgtcccaaga tagatacacg tgtatgatag tcaccaaatt ctgaaagttt
     4141 ctcagcgaat tcatttccgc ccattacacc ttcagccaag atgatcaagc aatgtttctt
     4201 cccgcgatcg cggccttctt ggattttttt agcaactgaa gccatatcaa aatcatgttc
     4261 tgggatgatg atttcatccg ctccgccagc cacacctgac cataaagcga tgtctcctgc
     4321 attgcgtccc attacttcga taacgaatgt acgaacatga gaagtcgctg tgtcacgaat
     4381 acggtcaatt gattctagta ctgtattgat tgctgtatca aaaccgattg tgaaatcagt
     4441 cccaggaata tcattatcga ttgttccagg aatacctact gctgggaaac cgcgttttgt
     4501 caaagccatt gcgccatgat aagagccgtc tcctccgata accactagac cttcgattcc
     4561 gaattttttc aattgttcga ttccttttaa ttgaccttct tcagttgcaa attctggata
     4621 acgtgcagaa tacaagaatg taccaccacg ttggatcttg tcacctacat ctgccacatc
     4681 aagacgacga atatctccag caactaaacc ggcaaaacca taattgatcc cgtatacttc
     4741 cagtccttcg taaatacctt tacgaacaac ggcacgaaca gctgcattca ttccaggtgc
     4801 gtctccgcca ctggtcaaaa ttccgatgcg tttcataata aacattcacc tcattaaaat
     4861 actttatcct aagtatgact taggtttaca accatttttg cgttaaccac gactaacatt
     4921 ctaacattat ttttctcact tgtcttgatt tacggataaa aaaatgaaaa aaaatgaaag
     4981 caagtagtat tttttaccgt aagttatttg aaaaccacat tatcttcgcc aagcagataa
     5041 ataagttgcc cctttatact cttgctgtca tccacccaat aagcatctga cagaactact
     5101 tttcgttgcg ttttttcgtg atacataact actggtatat atcctgggtg tttctgaaaa
     5161 atcacttgta attgtttcat tatctcggga tcttcccgtt cttctgtaat acgcaaatag
     5221 caagtttgtg aaggatactg ggcttctaac tggttaggat cagcaaagct ttctccaatt
     5281 agttgcagtt cctgattata tttgctgatt tcgctccgcc cttgaacaaa gatcactcga
     5341 tcaacggcaa acaaattacg atatttacga taaagagttg gaaaaactgt gacagaaatt
     5401 tctccactac tgtcggttcc ttcaacaaag gccatcagtt ctcctttttt tgtccgaatt
     5461 tctctaactt ccttgatcat cactaataaa ttgactggtt gattagggac gatatctgta
     5521 atcagctgaa cttgtttagc taaacgaaga cgatcaaacc cttctgcagg atgacctgac
     5581 aaataaatac ctaagtactc ctcttccagc ttcaagcgtt cttctagtgt atagtcagcg
     5641 acttcttctt cttttaatgc catgattccc agcaagtcaa gacttccacc actgtaaacg
     5701 atattttgga tttttccttc gagatcaagc atcaattgtt tcctgttagg agataattca
     5761 tcaaaaactc ctactgctgt cagtgattgc agtaactcta atttcagcca acgcttatcg
     5821 atccgtatga ggaattgatc cactgactgg aacgggccat tttgttttct ttcgtttaat
     5881 atatcttcta caaaatcacg ccgaatacct tttatcgctg tcagtccgaa tctgatttct
     5941 tccttattga ccaactcaaa actggaatta ctttgattaa tggacggcga ggaaagtttg
     6001 agtttatttt tacgtgcttc tgcaatatat tctttcaatt ttgatgtgtt atgccgaaca
     6061 gaattcatca ggctggtaaa gaaagcacct ggatgatggg cttttagata cgccatttgg
     6121 aatcccacga atgaataagc aaatgcatgt gaccgattga atccatagtt tgcaaatttt
     6181 tcgatatatt catatacggt cgctgctgtt ttttccgaat atccctgttg taatgctcct
     6241 gatacaaaat gcgacttttc ttcatctaat acgtcttttt tctttttact cactgcccgt
     6301 cgcagaatat ctgactgccc taatgtaaat ccagccatag tcgaggcgat ctgcatgatt
     6361 tgttcctgat agacgatcac tccatatgtg tttttcaaaa tcgggatcag tgaatcatct
     6421 gggtagcgaa tggcttcttt tcctttcttc ctggcaatga aggtatctat attttgcata
     6481 gggcctggtc gatacaatgc attgactgcg gcaatatctt cgatgttttc tggatctaat
     6541 cttcgtaaaa cgttccggat accagcagat tcaaattgaa atactcctga ggtttcgcct
     6601 cgttgaaaca agagcagcgt ttttgcatca tttagcggga tctcttttaa tcggatctca
     6661 tacccttcta ctcgcttaac agctttcaaa gtaaaatcaa taatcgataa gttgcgtagt
     6721 cctaaaaagt ccattttcaa aagaccgatt gcttctacct cattcatcgt atactgggtc
     6781 agaaaagctt catcagaacc gcgttggagc ggaactagtt caagtagatt cttatcgctg
     6841 ataactacac ctgctgcgtg agtcgaaaca tgtcttggca atccttctaa aatcactgca
     6901 gttttgaata aaagttggtt tttttcgctt gcctgaacta attctactaa ttgatgcgaa
     6961 gttttataag cttgggtcaa tgtgattttc aattgattgg gtattgcttt tgaccagcgg
     7021 tttgcttcac tttgcgataa accaaacact ctagctgcat ctctaagaac catttttgct
     7081 gccattgtgc caaatgttgc gatttgtgcc atatgatatt gtccatactt ttctcgaaca
     7141 taattcaata cttcttcacg tcgattgtca ggaatatcca aatcgatatc tggcatcgta
     7201 aagcgttcgg ggtttaaaaa gcgttcgaac agcaaatcat attctaatgg atccacatct
     7261 gtgatttcta acacataggc tactaatgaa cccgcagcag aaccacgacc tgcaccggta
     7321 acgattttgt ttctatgagc aaaagccatt acatcccata cgatcaagaa ataatcatcg
     7381 aatcccattt gatggatgac agataactcg tagtccaaac gttcttggta ttcctttgta
     7441 tagtcagtga ttcggcgttc cacttgcgaa tagcataact ctcttaaata ttctccagct
     7501 tgttttccat taggaactgg ataatgcgga agtaatttct gatggaactg gaattcaaat
     7561 gaaatcgatt cagctaaacg ctgggcgcct attacagctt gggaaagacc cgctttttcg
     7621 aatcgtttga tcatttcttg ttctgaaaga agatagacat ttgctgttag tggtaaagat
     7681 gcagataaat tttctaaagg tatttggctt ccctctttga tatgtttcat cacttcaagt
     7741 gcaaaaagtt cttcttgttg taaactagcg atgggatgta atgcacaaag cgaataattt
     7801 tcttttatca catactgata ccattcaggc aattgatcag gcgtgttttc tgtcaagccg
     7861 atataaaaat ttctagtaaa aacattttca agtaaaaact gccaatgacc gaaaaagtta
     7921 tcctctttat tgaaagcctc agaaacagaa tgatttgccg gaacaacaaa cgctagatgg
     7981 tcggtttctg tcatttctgc aagttccaat ttttcttgga tcatttttcg gctggaaagt
     8041 ttcatcagct gctgataacc tatttcatct tttgcgtacg caagcaagcc ataatttttt
     8101 tcttcataag tataactaag atgtaatcca atgattggct gtactccttc ttctacacaa
     8161 atacgataga attcaggtgc accgtataag acatctttat ccgttatggc taatgaagtg
     8221 tagccttgtt tttttgcttc ttgtacatat tctcgaatac gtatcgtact ttgtaaaaga
     8281 gaataagaag taattgtata aagttgtggg aaaaacatct tgcattccgc cttttttttc
     8341 gttaaaattc actagcgtta aaaggtttga tccttttact ttcattaaga tagcaggcgc
     8401 tgaagttgat tattccactt catttgcttg cttgtaatct gtaggaatga gttctttcgc
     8461 aagaactcaa attttattga gatttggtct cgtttcttta cattcaaaga aaatctggta
     8521 aaattaagat agaaaagagg tgttctttat gcgatatatc gttacattat tctgggctgt
     8581 cgttctaggt caagtagtcg gttatattgg tgctgcatta acaagcggaa catatgattt
     8641 tactttgaca acaatcattt cattcattgc gggtgtcatt atccttttga ttggtgcagt
     8701 tgcgccaaga aaagaaacct ctgcccattc gtaaaaaaac agccaagagc ttgagatttc
     8761 tcaagctctt ttttattttc tactcctcac caccattata atctgctgcg aagaacttta
     8821 cgaaagttga ataaagaaag aagaatattt gacagaacaa acaaacttgt cacaataaaa
     8881 acagcactgt aattataagc atgcgcgact gtcgatccta gcatgggacc taaaacttgt
     8941 ccaaagttgc taaacatctg attgtagcta tagattcggc tgactccttc ttgaggcgta
     9001 atcttactga tcagtgtatt gacagaaggc atcaaagcgc cagttgaaaa gcctaaaata
     9061 aagcgaagta tacctaattg gagcggtgta gtgacgaatg ccataggtaa ataacagcaa
     9121 aatgataaaa tgagtcctcc aattagaact ttttgattcc caatcttatc ccctagtttt
     9181 cctagtttcg gtgaagaaaa gacagcggaa acaccagcta tcgaaacaat caagccgctg
     9241 acaaaaagga tattttctgt acttccgctc aattcacgaa tatataaggt caaaataggg
     9301 ctgatcgtag tgattcctat ctgtaaaatc aaggtcgtaa tgaagagacc gatcaaaata
     9361 gagagatgat ccatttttga aaaaatttct ttggtgctta tcagatcttt tttctcgatt
     9421 ggatggaaat cttctttgac taagaaaatg gtcaataccg ttgtgatcat caacaaagcc
     9481 cctgtgatca agaatacatt ttccatacca aaccactgag ccagtgcacc gcccattgaa
     9541 ggtccgatca gatttccagc aatcgctccg gtagacaatg ttcctaacgc ccatccgctc
     9601 ttttctctag gtgcctgtga agcaatcatc gctgtggcat ttggaatata tccagacaaa
     9661 atcccattcc aaaaccgcat gatcaaaagc caatacgcgt ttggtacaaa agccaaagat
     9721 cccattgtta atgtcatccc tgctgctgca cggatcatca tgagttttcg gccttttcga
     9781 tcagctagat ttccccagat tggtgcaacc acggcagatg caaaagcagt cacagagatt
     9841 gctagtcccg aaaacaattc gatttgatct tttggtgttc ctagttgctc aacataaact
     9901 ggtatgaatg gcataactaa actaatactt gcaccagtga aaaaacagcc aatccacgca
     9961 atcactaaat tttttctcca attaatctcc atctatcatc cctctttcgt ctcttttatc
    10021 atacctattt tcgaataaac aagcaacgat ctcgccagta aaaagagaaa aatcccgcaa
    10081 aggtcatttt atatgtaacg ttctttttat gtaaaacaaa aagagatcag aacaaatact
    10141 gttccaatcc cttctcttta gttaaattgt tgctagaatg atgaagttga taatgaataa
    10201 aatatcaacg atccacaaag caacagaaac ttgattgtat tttcctttga ttactttcac
    10261 aattgtatag aaaataaatc ctgctgcaat cccataggaa atgctatagc acaatcccat
    10321 aaagatcgat gcaaagaagg ccggtaaagc ttcttccata tctagccatt tgatgtctgc
    10381 aaaagaagcc atcatcatta ctccaactaa aatcaatgct ggcgcagttg cttgatttgg
    10441 tacaatggcg atcagtggag agaataaact acttaatgcg aatagcactg ccactactac
    10501 tgaagtcaaa ccagtacgtc caccggcccc gatcccagct gcagattcga cataagttgt
    10561 tgtattcgat gtaccaaaga tagcccccac agaagtagcg atcgcatcgg caaatagtgc
    10621 tttatccatt tttgttttga acccacgacc atcttccaac gcgatctcgt cttcttttga
    10681 gaaaatacct gtgcggcgtc ctgtaccgat aaatgttccg atcgtatcga aagtatcaga
    10741 taaactgaat gcgatgatcg tcatcaatac ttgaggaatc ttggaagaat cactgaataa
    10801 agattgcatg ccttcagaac caaatgctgc accgaaagtt gttcctaatt ctttaaatga
    10861 attacctaac gaattcgttt gccaatcaat ggaacttaaa tcaacaacac ccataaaaat
    10921 accaaggact gtggtcgcta cgataccgat aagaatagcc ccacggacat tttttacaac
    10981 taaaatggct gtcagtacca aaccaatcac agccaataag ataggagcgt tgtcaaagtt
    11041 ggctaacgca gggacgattc caccatttat cgtaacattt gtcgcttttc cgccttcaac
    11101 gacagagctc gaaatagctg actggtctgc tgaaaaagat aagaatcctg catttttgat
    11161 tccgacatac gcaacgaaaa taccgatccc gccaccaatc gcatgttgaa gactttcggg
    11221 aatcgcccga ataatcattt ttcgaatatt tgtgacagta ataaaaatat tgattaatcc
    11281 gcaaataaac accattgcca aggcttgttg ccaagaataa ccaagcccaa aaacgaccgt
    11341 aaaagtgaaa aatgcgttca atcccatacc aggtgcctga gcatatggta catttgcgaa
    11401 caatcccatt accagcgtac caataatcga tgcaatgatt gtcgctagaa atactgcttg
    11461 gaagggcata cctgatgctg acaaaatcgt cggatttacg aataagatat aactcatggc
    11521 aaagaatgtc gttactcccg ccattatttc agttgataca tttgtattgt ttttctttaa
    11581 accgaaaaac ttttccataa aaagttccac tccctgaatt tttttctgat ggaaaactat
    11641 aataataaaa aataagtaaa atagggcaaa tccatcgaac aatttcaaat tatatagacg
    11701 tttcattcgc ttttcaacgt ttttttaaca aaaaaagcga aaataatact taacgttcgt
    11761 gtttagctta tgtttagcta tttatatagc cataactgta gtttttgtta ggaatagctg
    11821 attgctcttg ttaattacct aaaatatgct agactaaaac aaatgctagt tgaggaagga
    11881 aggaccctta ttgaataaaa aattaattgc catcgatctg gacggaacta ccctcaatca
    11941 agattcgatg attacatcta aaacaaaaga gactctaaaa aaagcaatca atgccggtca
    12001 tcatgtcagt attgctacag gacgcccatt ccgaatgagc catcagtttt accaacaatt
    12061 agaattaaca acaccgatgg ttaattttaa cggcgcatta gtacacatcc ctaatcagca
    12121 ctgggatggt gaaagagaaa cgttgatcaa tcgtgaaatc gcttttgaaa tcttatcgca
    12181 aaaaaagcag ctaaatttag attttatcgc tgctgaaaat cgtgatactt tttttattga
    12241 cagttttgat ttctttgatg aaaaaatttt tgcttcttct cgtccaggag agaagaattt
    12301 gctttctcct aaaaatttga cgacaaatcc tacatctttg cttgtccgaa cagacaaacg
    12361 ttttgcagga gctgtatctg ctgaattaac acgtcaattt ggcagttatg tcgatgttcg
    12421 gacatggggt ggacctactg ccatcttaga gattgtttca aaaggaatcc aaaaagcaaa
    12481 aggcgtgcaa gagattgcta actacctgtc tatcgatcaa aaagacgtca ttgcctttgg
    12541 tgacgagcat aatgatttgg aattgttgga ttatgcaggt tggggagtag ctatggctaa
    12601 cggtactgac caactcaaag gcattgcaaa tgatgtcact cctttgagca atcaggaaga
    12661 cggtttagct gtttatctgg aaaaactact taaactataa tagagaatta gattccacaa
    12721 aaaagaggtt gtgac
//
LOCUS       DACCVH010000081        12683 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.081, whole genome shotgun sequence.
ACCESSION   DACCVH010000081 DACCVH010000000
VERSION     DACCVH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.081"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(287..649)
                     /locus_tag="IVV98_002314"
     CDS             complement(287..649)
                     /locus_tag="IVV98_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807915.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="IVV98_002315"
     CDS             complement(723..1103)
                     /locus_tag="IVV98_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP7807916.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="IVV98_002316"
     CDS             1185..2360
                     /locus_tag="IVV98_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7807917.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="IVV98_002317"
     CDS             complement(2437..3021)
                     /locus_tag="IVV98_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7807918.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="IVV98_002318"
     CDS             3222..4220
                     /locus_tag="IVV98_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7807919.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="IVV98_002319"
     CDS             4332..4841
                     /locus_tag="IVV98_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP7807920.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4871..5530)
                     /locus_tag="IVV98_002320"
     CDS             complement(4871..5530)
                     /locus_tag="IVV98_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP7807921.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5532..6296)
                     /locus_tag="IVV98_002321"
     CDS             complement(5532..6296)
                     /locus_tag="IVV98_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP7807922.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6304..6981)
                     /locus_tag="IVV98_002322"
     CDS             complement(6304..6981)
                     /locus_tag="IVV98_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP7807923.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7018..8403)
                     /locus_tag="IVV98_002323"
     CDS             complement(7018..8403)
                     /locus_tag="IVV98_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP7807924.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8613..8697)
                     /gene="ffs"
                     /locus_tag="IVV98_002324"
     ncRNA           complement(8613..8697)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IVV98_002324"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="IVV98_002325"
     CDS             complement(8720..9235)
                     /gene="tadA"
                     /locus_tag="IVV98_002325"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP7807925.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9341..10198
                     /locus_tag="IVV98_002326"
     CDS             9341..10198
                     /locus_tag="IVV98_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP7807926.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10279..10614)
                     /locus_tag="IVV98_002327"
     CDS             complement(10279..10614)
                     /locus_tag="IVV98_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807927.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10681..12051)
                     /locus_tag="IVV98_002328"
     CDS             complement(10681..12051)
                     /locus_tag="IVV98_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP7807928.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12129..12665)
                     /locus_tag="IVV98_002329"
     CDS             complement(12129..12665)
                     /locus_tag="IVV98_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7807929.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         3768 a         2574 c         2118 g         4223 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgatatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt ttgtttgttt caagctattt tttcctaaga
     4921 aaagaaaaac agcaaaaaat aattctaata atacaaaaaa taagataaag ctatgcatga
     4981 aaaattcttc tggaagtaca ttgatgattg gatcagtaac gggatcgaat aaccagtcat
     5041 cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg atcaaatcct atcatcatga
     5101 aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa cggacgaatc aaccgccaaa
     5161 gccgatcatt cttttgcaaa tatttgataa acaaaatact cgggatcaaa gtgatgaaaa
     5221 acacagcata atccactaaa aacaaaattt tcacttcata aaagtgatgg gctccgctag
     5281 cagaaactgg gaaatctggc aagctgagga tggttttgaa gggattattg agataattca
     5341 ttaggtgatc aaaatttttc agtaacgtct cttgatctaa agaagtataa tccaaaattt
     5401 gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt gatcgtcaca ccaactgcca
     5461 gactgatcag tgtcagaaat aggctgaaca atccagcata ttccatccac tgccatctcg
     5521 aatttttcat attagaagct ccattcatcc agtgattgtt tcacataggt agctgggata
     5581 ggcaacccag gtacatcttc ttcttttgta aaacctgata aaacgagcaa agtatctata
     5641 ttattgcgta tcccagcttg gatatctgtt tcatagttat ctccaaccat gattacttct
     5701 tctttttgca gccctaatac ttcaacggct ttatccataa tgatggcttc tggttttccg
     5761 atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag agatgactga ccctgctcca
     5821 ggaagaaggc cgcgttcagt aggtatattc ttatctgggt tcgttccaat gaaagtagca
     5881 cctttttgaa tagcaagtgt tgctttaact actttttcat aggtcagata attatctaag
     5941 cctaccacta catagtcagg agcctcttct tcccatgtaa atccggcagc taaaatcaag
     6001 tcaatcaatc ctgcttctcc gataacatag acttttttcc cttttccatc tgctttcata
     6061 aaatcgattg ttgccaaagt agctgtgtag actgtctctg gagctacatg aatgtcaaac
     6121 tcatctgcta gacgattagc tactgtttct ggtgacttag tcgtgttatt ggtaacaaac
     6181 aagaaaggta attttctttt ttgcaattct tccacaaatc gtttaccggc cggtatgggt
     6241 tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat atcctttata gtccattcat
     6301 ccactactct tccctttttc tgatcgtaaa tgctgttttt gttttttcta cttgtttagg
     6361 ttgttcttgt ttttttactt tttcagaggt ttttgctgac tctgtttttc gatttttaat
     6421 aaccggtttt ttgcgattag atgcgactgg tccttttttc tcatcgatat acgcacgatt
     6481 atggtttttt ttcttttttc ggcgctgagt tgtcttttct tttttaccgc cgattctctc
     6541 gatgacaaaa tacgcacaac caaaattgca atattcgtaa agatagtctt ccaaggaatc
     6601 gattcgctga tctggatgcg cccgtcgatt atccgcttgg aaaaatcctt ttaggcgtag
     6661 ttgttcataa ccccaatctc ctacgatata atcatatcgg gctagtacat cactgtaacg
     6721 ttctccaagc ttttctgcat taaatccttc acgataatcg gacacaagcc gataatgtct
     6781 ttcacctatc aaaaaattac tgtcatctaa cagtgtcact agctcgcctt tgactttttc
     6841 tgctttaggc tcctcaacga tttcttccaa agcagctgtc agttcttcgg tgactgttgt
     6901 ttcctgttca gctgatgatt ttttcttagc aatttctgtt ttatgctcaa cgttctgctg
     6961 ttcattttgt tttgcagaca tgcgttcacc acctatcttt tttattatac cttgttttta
     7021 tttgattggg tagtgagctt tcaagtaatc tcctaccaca cttcggataa attcagggaa
     7081 caaaaattca ttttttccag caatctcaat cgttggaaaa aatggaacaa acatcaaatg
     7141 atctacggta gtaaaagtat aatttttatt cagatcgatt ggcttgttct tccaaaagac
     7201 ttgatggtta atagaatcat atgtgattcc attatagacc atctgcccaa aaatcttacc
     7261 gcgaaatccc attcccttca taggatagtt acgtaaaaag ttacgatttt tttctatttc
     7321 taaaactaag cggatcagat catttccacc caatgtgaca tttaacaagt gcatcggatg
     7381 cggcaacgca gtgtgaagct gatcctgatt gacccgccct tttggaattt cagttaaaaa
     7441 cagaccactg tttaatattg ctgcttccgt ctttcctcgt tctttcaccg cctcaaaggc
     7501 tacttggata aacgaatgct cattgaagat atctagactc agagaaaatg gcaaatctgc
     7561 tacttctttt tcttttaata attcatgccc acgttctaga caactattta tttcttgttc
     7621 atcttctgta aaagctgtca ttgtttcggt agggatggct ttggctgaat gcttaaggat
     7681 ttttttctct tcatcgatgg ttaaatggac ttcaccgaca tactgcccgt actttccagc
     7741 ggctgctatt tggacatcat tgattacgtg accttctctg aataaatgat gggtgtgcga
     7801 tcctaaaata acatcaattg ctggtatttc ttttgcaatt tggaaatcat cctgaatccc
     7861 gagatgactc atcaaaacta aaacatccac ttgtgaacgt aaatcttcga ctaattctgg
     7921 caaaatatca taaggattcc gtatgtccca gccattcgga ttataagtaa gcggaaatgg
     7981 agcagtaaat gcaattagtc cgattttcgt ctggtgtttc gttgtaatga ttttatatgg
     8041 tttcgtccat gccggtggct ggagcgtatt tttatcgaat aagttatcca ggatgatatc
     8101 aaactcagca tgatcgtata aatgattcaa ctcttctttg gaatttccta cgccttcatt
     8161 gtttcctatc gtcgctgcat cataaccaac ttcattcatc agcaagatat tttcctgtcc
     8221 attcgttgct tctgacaatg gatgccaacg atccacaaaa tcacctagat ctactgcaat
     8281 cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt tgatccaaaa accttctgat
     8341 ccttggccaa ttttctaaat gagaatgcag atcattcgta tgtaaaatca ctattttttc
     8401 catgtaccct ctcgcctctc tttatcttta tcataccata ggcagctttt tcttccattg
     8461 aaacaagctc tatttcagag tttttcctgc cttgaagcaa attgtataag tacaatattc
     8521 gataaatcag tctggctaaa aaatcaggaa cattcatttt tacagtacta taaaaataaa
     8581 aaaaacagac ccgaaagtct gttgtcgttt cattataatc agacacatgg cggaacctgc
     8641 ttagtgctgc ttccttccag acctgacacg cttcacaagc ccaccattgt cctagccttt
     8701 cggcaaagaa tagtatacct tatttttcat tcgttgacca gtcttttttt aatttctttt
     8761 ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat cccacattcg tcttctaaaa
     8821 tgccaccttc tacatatgct tggtggttaa accgctcgtc ctccaaaaga ttcatcaagg
     8881 taccggctgt tccgcctttt ggatcatacg cgccgaaata aacttctgct acacgagaca
     8941 aaatcatcgc gccgctgcac ataggacaag gctctaaggt aacaaaaagt gcagcatctt
     9001 ccaagcgcca gcttcccact ttttcacagg cttccttgat tgcaagcatt tctgcatgtg
     9061 tagtagcatc ttgcgtggtt tctctaaggt tatatcctct tccaatcact tttccatcca
     9121 atacaaccac tgctccaatc ggaacttcat gaagcatttc tgctttcttt gcttctgcca
     9181 atgcaaggcg catccatttt tctttttcta ctgcatcaag atttgtattt accaattacc
     9241 cttccctgcc tttgtttttt cttgttttac tttagcatat gataaaaagg ctgtaactaa
     9301 ctttttttct atggtaaaat aaatacaaga ggtgaacaag atgaaaatgg ataaattact
     9361 tgctctttac ccacaagcac agaaaaaaaa ctctccagca tcagaagcgg atatcctttc
     9421 ttttgcaatt gatgatgctt ttatctggat caaacaagat tcattatctc aacaagaaac
     9481 cagccttttg aaagcgttat tccctgtaat caacgatcaa aaaaaacacc catggtatca
     9541 ctatcttttt aaagatgctt cttgtgttca agaaaaaagc tttcgtttga tccagcttca
     9601 cgtcgaatca aaaggagaat tcttaaaaaa agaatggcaa gatactattt tggaattatt
     9661 tcgctattct gctgatttct ttttttatac agacacagat gcgctcttag tcgaacaaat
     9721 aaaccgtgat tatcttgatg ctactgaaat caacggtatt tttctatctt tagatgctga
     9781 ttttgatacg acaacgtctg tattcgttgg ttctttccat tcacctggca ccgacctcgt
     9841 ccctttgttt gctgaagaaa gaaaaatttt tttaacagag caaaacaatc tttatactca
     9901 cagccgtact ttttctatgc aagatgtggc tttacattac tatacaaaag atactgtaaa
     9961 agatagtaag ttgatcaaaa gttacataga actgatcaaa caaaatgaaa tggaagtgat
    10021 cattcaagaa ttatggaatg aattaggcaa tgtcagctct gctgcaaaaa cactgtttct
    10081 tcatcgtaat actctaaaat atcgaatcga aaaatttcaa gaacagtctg gtttcaatct
    10141 aaaaaaagcc aacgatttac tgttttgcta tcttttattg cttcatgaac ataattaaag
    10201 atagattaaa ggggttgtga caataatttt gtcacaaccc cttatttcga atgaatagtg
    10261 ttcaaaagct agtttctctt acatcatttt ttcaacaaaa tgcattagcc ggtcttttac
    10321 atcttcggtt gaatctttga ttgaatcacc ataaacagag attttctttt ttcctgattt
    10381 gatttttgct aacattccca tcaaagaatc caagtcacta tctgaaagac catctacgat
    10441 ttctagtaat ttttcatttc catcaaattt gtcatagacg aattttttta ctttcgtccg
    10501 agtagtcata tgatggatct tttccattac ttttcccgat acaacgactg ctgtcgctac
    10561 actggcagcg gctgctacgc ttaatccgat tgttactttt gttgatgttt tcataagtat
    10621 cagctccttt ttatctatct ccatcatagc atagacaaaa aaataaacga actaatccac
    10681 tcagtgaaat ctcaatcctt tagggaaaaa gttctttact gttcctttta cttgtttccc
    10741 aaatccgaca ggtatcttat ctaatactag caaaacccat ccttgattcc catcacgttg
    10801 aaatgtttct cctgctgtgt aagattgcca ttccttttga gtgatcggca agcaaggtat
    10861 attctctatc ttttttgtag caagcgctaa tgcatagcta ggttcaaatc gattcttttt
    10921 gaaatctcct aaatgcaaac ctgtacgtac gacttttaaa ccatcgagag aaggggctaa
    10981 ctcaggaact tcccaaagat ggtcgttgaa cactaaaagt cttccagtag cttcataatg
    11041 aaaatcattt gaaaactccg tccagagttt ttcctgctct tttgtcattt gcactttact
    11101 tttttttcgt gtcttctttt ctttatgcat ctgattttgt ccatgaaaag tcagctttgc
    11161 aacaaaatgt ccttcaccct gatctttatg aggccatata cgtattgttt tttccaaacc
    11221 agctacgctt ccccattcag aacgtcctga actaacggat tgagtcaaag gaatctcctc
    11281 aatcgttact ggataatttt ctacaagcca gctaatgatc tcttcatttt cttctggtgc
    11341 aaacgtacaa gtcgaataaa tcagttgtcc tttatttttt agcattttta ttgctgaaga
    11401 caaaatctct tgctgacgtt tttgacagta tagcggagat tcttctgtcc actcttttat
    11461 tgcatttgga tcttttcgga acattccttc tcctgaacaa ggagcatcaa ccacgatccg
    11521 atcaaaaaag cccgaaaaat gagggacaag ttctgcgggt gcatgatttg tcactattgc
    11581 gttcgaaact ccccatcgtt ctatattttc tgataaaatc ttcgcacgtt tcggaaagat
    11641 ctcattcgtc actaataacc ctttcccctt catttgagca gctaattggg ttgatttacc
    11701 accgggagcc gcacacaaat ccaaaacttt ttcaccgggt tttgctgcag cagctgttcc
    11761 aacgatcatt gcacttggtt cttggctata ttcataccca gcttgatgga ggaaagactt
    11821 tccattgaca gtgccaagaa atccctcatt gctgtaggga gcgggttgta attcttcgct
    11881 atggtaagtt tggaccatgt ccaatcctgc cggttttagt ggattccacc gaaatccttt
    11941 tttcacgctt ccttgttcaa gcgcagaaaa aaaatcggat gcttcttcgc ctaaaagaag
    12001 acgatatttt ttgataaatt gctgtggtaa cgttgtcgct tcctccttca ttccaatgtt
    12061 tcgttagaca ttttacaatc ttttttacga aaaataaagg tggctgatct actttttcat
    12121 gttgctgcct aaggtgactg ttcctttaag atattttcca agtattcatc cgtcacctcg
    12181 tttttatccc aaacagcgtt catcatttca agaaaatctt gagaagaatc atctgagcgc
    12241 aaacttccca atgcattaag ccataccaat tcaagcgact tttcttcttt gatcttcgtg
    12301 tgacctttga catatgagaa aaatggccgc ttaaatagcg aatccatgtc taaatcagat
    12361 tttgcaatga tttcacgaat actttcatgg atagaaaaaa aatctttcaa taagtagaca
    12421 atgcttaaaa catcatcgga actgcattca gctaagtagt tttcaaaata aacagtgatt
    12481 tcttctaata tcttctcttt taacccgctg attgatttga aatgtgtata aatcgggtat
    12541 gtagaacaac cgcagaactc tgctaactct cttgcagtaa ttgacttcat tccatattct
    12601 tccacgtata ccatactttt gaacagcaaa tattctttac tataatttgt tactctcccc
    12661 atcattctta cctccgtctc ttt
//
LOCUS       DACCVH010000082        12432 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.082, whole genome shotgun sequence.
ACCESSION   DACCVH010000082 DACCVH010000000
VERSION     DACCVH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.082"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..190)
                     /locus_tag="IVV98_002330"
     CDS             complement(<1..190)
                     /locus_tag="IVV98_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807930.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="IVV98_002331"
     CDS             complement(200..1015)
                     /locus_tag="IVV98_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7807931.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="IVV98_002332"
     CDS             complement(1277..1720)
                     /locus_tag="IVV98_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAP7807932.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="IVV98_002333"
     CDS             complement(1854..2192)
                     /locus_tag="IVV98_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7807933.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="IVV98_002334"
     CDS             complement(2180..2557)
                     /locus_tag="IVV98_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7807934.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="IVV98_002335"
     CDS             2781..3974
                     /locus_tag="IVV98_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7807935.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="IVV98_002336"
     CDS             complement(4140..4562)
                     /locus_tag="IVV98_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7807936.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="IVV98_002337"
     CDS             4957..5151
                     /locus_tag="IVV98_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807937.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="IVV98_002338"
     CDS             5148..5594
                     /locus_tag="IVV98_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807938.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="IVV98_002339"
     CDS             complement(5804..6976)
                     /locus_tag="IVV98_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7807939.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="IVV98_002340"
     CDS             complement(7182..7997)
                     /locus_tag="IVV98_002340"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7807940.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="IVV98_002341"
     CDS             complement(8147..8593)
                     /locus_tag="IVV98_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP7807941.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="IVV98_002342"
     CDS             complement(8590..9594)
                     /locus_tag="IVV98_002342"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP7807942.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="IVV98_002343"
     CDS             complement(9634..9963)
                     /locus_tag="IVV98_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP7807943.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="IVV98_002344"
     CDS             complement(10089..12416)
                     /locus_tag="IVV98_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7807944.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3513 a         2430 c         2272 g         4217 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aa
//
LOCUS       DACCVH010000083        12304 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.083, whole genome shotgun sequence.
ACCESSION   DACCVH010000083 DACCVH010000000
VERSION     DACCVH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.083"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..339
                     /gene="merR"
                     /locus_tag="IVV98_002345"
     CDS             <1..339
                     /gene="merR"
                     /locus_tag="IVV98_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HAP7807945.1"
                     /translation="IRYYERKNLLQEPHRTEAGYRIYSYDDVKRVGFIKRIQELGFSL
                     SEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKRIETMLDDLKQRCPDEKQL
                     HSCPIIETLT"
     gene            368..2263
                     /gene="merA"
                     /locus_tag="IVV98_002346"
     CDS             368..2263
                     /gene="merA"
                     /locus_tag="IVV98_002346"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HAP7807946.1"
                     /translation="MNKFKVNISGMTCTGCEKHVESALEKMGAKNIESSYRRGEAVFE
                     LPDDIEVESAIKAIADANYHPGEAEEFQSEQKTNLLKKYRLNVEGMTCTGCEEHIAVA
                     LENAGAKGIEVDFRRGEALFELPYDVDIDIAKTAITDAQYQPGEAEEIQVQSEKRTDV
                     SLNDEGNYDYDYIIIGSGGAAFSSAIEAVTLNAKVAMIERGTVGGTCVNVGCVPSKTL
                     LRAGEINHLAKNNPFVGLHTSASNVDLAPLVKQKNDLVTEMRNEKYVNLIDDYGFELI
                     KGEAKFVNENTVEVNGNQITAKRFLIATGASSTAPNIPGLDEVDYLTSTSLLELKKVP
                     NRLTVIGSGYIGMELGQLFHNLGSEVTLIQRSERLLKEYDPEISEAITKALTEQGINL
                     VTGATYERVEQDGDIKKVHVEINGKKRIIEAEQLLIATGRKPNTESLNLHAAGVEVGS
                     RGEIVIDDYLKTTNSRIYSAGDVTLGPQFVYVAAYEGGLAARNAIGGLNQKVNLEVVP
                     GVTFTSPSIATVGLTEQQAKEKGYEVKTSVLPLDAVPRALVNRETTGVFKLVADAKTL
                     KVLGAHVVAENAGDVIYAATLAVKFGLTVGDLRETMAPYLTMAEGLKLAVLTFDKDVS
                     KLSCCAG"
     gene            2423..3745
                     /locus_tag="IVV98_002347"
     CDS             2423..3745
                     /locus_tag="IVV98_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7807947.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNPILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGHLRYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTPIKNLEKGDL"
     gene            complement(3872..5377)
                     /locus_tag="IVV98_002348"
     CDS             complement(3872..5377)
                     /locus_tag="IVV98_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepS protein"
                     /protein_id="HAP7807948.1"
                     /translation="MKVSDVISVILKSGIREYKCLNSKIKPIGYKAEGKKGAIFGFRS
                     KKLMTESRGIVLTSQEGLAENEDKFTHWTPNVYSYGAYADEKRIIVKGHNERNLQQIN
                     TFVIDFDRLTGEKLDSQMILDAAIDLELMPTLILETPGGFQAYFILENAWYISSKNNY
                     QSIEVAKRVSENLRKAFAEELPSVDLGCNHFGIARIPRTDNIVYYYPALTHDIQQLIQ
                     WSMKYEPAKTYKKPLLSLVKNKYKQVNEMWYRQLISNPKIVGAKGIMGRNNVIFTLSL
                     ANYASGVDLEDCLNEMDLFNSSLERPLKDRERVRIVKSAYSGKYRGASKTYVQELVSN
                     WGLESLSEEKMFTQQRNTWYKFKKERHKRKKSHLSEWKEDILAYLETQCYRYRPEVRL
                     KKTDLQAAITFNGQSIPKRSLDRALKELMAEGKLFVQIKAGRNGGLVVATRKALIRTV
                     IQVKQQVKSAYKQGIKTFFKEADMLVRIFREPDKYSQRVDHYKQLNLWNTG"
     gene            6081..6971
                     /locus_tag="IVV98_002349"
     CDS             6081..6971
                     /locus_tag="IVV98_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7807949.1"
                     /translation="MANTIIFGQQKGGVGKTTDTCMITLVAAMLMKKRTILIDIDLQA
                     NATNFMTKTFGVETVPQTLMSALENGDLRPAIVNLKENLDLIPAGYDMRLYTEFLTEN
                     FDNTIDRTFYLKNLIEEIKDDYDYIFIDIPPSTDLKVDNAMVACDYLVVVQETQQFSF
                     EGSQRLIFDYIQTLVDDFGSDVPIQIAGILPALLQQKRPMHQKLVEETIDTFGRDNVF
                     NTIIQNHARLEWYPRIGFQFQDYHDKKMIALFADIFCELEERITLYKSNGDIQDYFYT
                     PRYILDGKLTSLGKEISLNV"
     gene            6964..7248
                     /locus_tag="IVV98_002350"
     CDS             6964..7248
                     /locus_tag="IVV98_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807950.1"
                     /translation="MSSLINRKIPQGATANKEADTKRKVTIQKKSSKKILASERKNIK
                     VSPSTFDLIKTISTMKSYKNYEFIDKAVESYIQNNLTEREQRILKNLISK"
     gene            complement(7281..7520)
                     /locus_tag="IVV98_002351"
     CDS             complement(7281..7520)
                     /locus_tag="IVV98_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010621028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807951.1"
                     /translation="MEQSDNVPLDRHKCKEHVFKDKRFVEKESESLTLLGYKIVVDTV
                     TGVNYLETPKGGITPLLDKNGKICIDKKKSINKKG"
     gene            complement(7916..8113)
                     /locus_tag="IVV98_002352"
     CDS             complement(7916..8113)
                     /locus_tag="IVV98_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7807952.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYKQKQGEYVAITIIKE"
     gene            complement(8147..8446)
                     /locus_tag="IVV98_002353"
     CDS             complement(8147..8446)
                     /locus_tag="IVV98_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807953.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            complement(8487..9104)
                     /locus_tag="IVV98_002354"
     CDS             complement(8487..9104)
                     /locus_tag="IVV98_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807954.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            complement(9429..9824)
                     /locus_tag="IVV98_002355"
     CDS             complement(9429..9824)
                     /locus_tag="IVV98_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807955.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            complement(9904..12255)
                     /locus_tag="IVV98_002356"
     CDS             complement(9904..12255)
                     /locus_tag="IVV98_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP7807956.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
BASE COUNT         4025 a         2230 c         1974 g         4075 t
ORIGIN      
        1 atcagatatt acgagcgaaa aaatttatta caagaacctc accgaacgga agctggttat
       61 cggatatatt catatgatga cgttaagcgt gttgggttta ttaaacgaat acaggaactt
      121 ggtttttctt taagcgagat ttataaatta cttggtgttg tagataaaga tgaagttcgt
      181 tgtcaagata tgttcgaatt tgtttctaaa aaacaaaagg aagtgcaaaa acaaatagag
      241 gatttaaaac gaattgaaac tatgttagac gacttaaaac aacgatgtcc agatgaaaag
      301 caattacatt cgtgtccaat aatagaaaca ttaacatgag agattaatta acgaaaggag
      361 cttttttatg aataaattta aggtaaacat ttcaggaatg acttgtacgg gttgtgaaaa
      421 acacgtagaa tcagcacttg aaaagatggg tgctaaaaat attgagtcta gttatcgtcg
      481 tggtgaagca gtatttgaac tgcccgatga tattgaggtt gaaagtgcaa taaaggcgat
      541 tgctgacgca aactatcacc cgggcgaagc agaagaattt caatcggaac aaaagacgaa
      601 tttattgaaa aaatatcggc taaacgttga aggaatgacc tgcactggtt gtgaagaaca
      661 tattgcggtt gctcttgaaa atgcaggtgc aaaagggatt gaagtagact ttcgtcgcgg
      721 agaagcactg tttgaactac cgtatgatgt agacattgat atcgcgaaaa cagcgattac
      781 tgacgcacaa tatcaaccgg gcgaagcaga agaaatacaa gtgcaatcgg aaaaaaggac
      841 agatgtaagt ttaaatgatg aaggtaacta tgattatgat tacatcatca tcggttctgg
      901 tggagctgcc ttttcatctg ccattgaagc cgttactttg aacgcaaaag tggctatgat
      961 tgagcgtgga acggtgggtg gaacttgcgt taatgtcgga tgcgttcctt ctaagacctt
     1021 attaagagca ggggaaatca atcatctagc aaaaaataat ccatttgtgg gattacacac
     1081 ttcggcttca aatgttgatt tagcgccatt agtaaaacaa aagaatgatt tagtaaccga
     1141 gatgcgaaat gaaaaatatg tgaatttaat tgatgattat ggttttgaat taataaaagg
     1201 tgaagcaaaa ttcgtaaatg aaaatacagt tgaagtaaat ggcaatcaaa tcacagccaa
     1261 aagattttta atagctacag gtgcttcttc aactgcacct aatattcccg gattagatga
     1321 agtagattat ttaacaagca ctagcttatt ggaattaaag aaggttccaa atcgtcttac
     1381 cgtaattggt tcaggatata tcggcatgga attaggacaa ctatttcata acctcgggtc
     1441 agaagtcact ttgattcaaa gaagcgagcg tctattaaaa gaatacgatc ctgaaatttc
     1501 agaagccatt actaaggcct taacagaaca gggaattaat ttagtaacag gtgcaaccta
     1561 tgaacgagtt gagcaagatg gagacattaa aaaagttcat gttgagataa atggtaaaaa
     1621 gcgaattatt gaagcagaac aattgctaat tgccactgga agaaaaccaa atacagaatc
     1681 attaaactta catgcagcag gcgttgaagt tggttcccgt ggtgaaattg tcattgatga
     1741 ttatcttaaa acgaccaatt cccgaattta ttcagctgga gatgtcactc tcggtcccca
     1801 atttgtttat gtagctgctt atgaaggtgg acttgctgct cgtaatgcaa tcggaggact
     1861 aaatcaaaag gtcaatttag aagtggttcc aggcgttacg tttacttctc catcgattgc
     1921 aacggttggt ttaacggagc aacaggcaaa agaaaaagga tatgaagtga aaacatcggt
     1981 attgccgttg gatgctgttc caagagcgct cgttaatcgg gaaacaacag gtgttttcaa
     2041 attagtggca gacgcgaaaa cattgaaagt gttaggggcg catgtagtgg cagaaaacgc
     2101 aggagacgta atttatgcag caacattagc tgtgaaattc ggtttaactg ttggagatct
     2161 gagagaaacg atggctccat atctaacaat ggcagaagga ttgaagctgg ctgtcctaac
     2221 ttttgataaa gatgtttcga aattatcttg ctgtgcaggc taagggaact tttttacaac
     2281 tccctattca agtgaaccag ctaatgcttt aagggatttt ctaagtgcat ttgtggtcac
     2341 aaaaataatt taacactgat gatttcgaca tcaaatctat aattgatacc ttaacaccgc
     2401 agagtaataa aggatgaata atatgtcaga cttattatcc ctaccagaca ttaaaacaat
     2461 agagccgcca caagaaaatg aaaccgatat gatgtttaaa gttgaagcag tcggaccacc
     2521 tgaacgttgt cctgaatgtg gttttgacaa gttgtacaaa cacagttcaa gaaatcaact
     2581 aattatggat ttgcccattc gtttaaagcg agtgggctta caattgaacc gtagacgata
     2641 caagtgtcgt gaatgcggat ctaccttctg ggaacgccta atatctgtag atgagaagcg
     2701 tagtatgacc aaaaggcttt taaagtccat tcaagagcaa tccatgtcta agacctttgt
     2761 agaagtcgca gaaagcgttg gtgttgacga gaaaaccatt aggaacgttt ttaaggacta
     2821 tgtggcactc aaagaacgtg aataccagtt tgaaactcct aagtggcttg ggatagacga
     2881 gatacatatt atccgtagac ctcggcttgt attgactaat attgaacgca ggactattta
     2941 tgacatcaag cctaaccgta acaaggaaac agtcatccaa cgtctttcag aaatcagtga
     3001 caggacttac attgagtacg tcacaatgga tatgtggaag ccctacaaag acgcagtgaa
     3061 ccctatcctt ccacacgcta aagttgtcgt agataagttt catgtagtta gaatggctaa
     3121 tcaagcctta gataacgtca ggaagtcttt gaaagcccat atgagccaaa aagaaagacg
     3181 tacccttatg cgtgaaaggt ttatccttct aaagcgtaaa cacgatttaa atgaacgtga
     3241 atcattcctc ttagatactt ggttaggtaa tcttcctgct ttaaaagaag cctatgaact
     3301 caaagaagag ttttactgga tatgggatac tcctgatcca gatgaaggtc atcttcgtta
     3361 tagtcaatgg agacaccgtt gtatgtccag caactctaaa gacgcatata aagacctcgt
     3421 gagagccgta gacaactggc atgtcgaaat attcaactac tttgataaaa ggctcactaa
     3481 tgcttatacg gagtcaatta acagcattat taggcaggta gagcgaatgg gtagaggtta
     3541 ctcgtttgat gccttacgag ccaaaatcct tttcaatgag aagctccata aaaagcgtaa
     3601 gccacgattt aattcaagtg ctttcaataa agctatgtta tacgatactt tcaattggta
     3661 tgaagtgaat gatcacgaca ttacagacaa ctttggtgtc gatttttcca cacctattaa
     3721 gaatttggag aagggtgatt tataagccct tttccaccat aaaatccgaa tacccaaaaa
     3781 aacaaaaata tacagaatta ggataataac taacaaaaac gaaaacaagt ataaaagaaa
     3841 tataatgtat aggcacttga catgttttat tttatcctgt attccacaaa tttaattgct
     3901 tataatgatc tactctttga ctgtatttat ccggttctct gaagattctt actaacatat
     3961 cggcttcttt aaaaaatgtc ttaatgccct gtttgtacgc agattttacc tgttgcttca
     4021 cttgaatgac cgtacgaatt aacgctttac gagtggcaac tactagtccc ccattccgtc
     4081 cagcttttat ttgtacaaat aatttacctt cggccatcaa ttcttttaat gcacggtcaa
     4141 gagaacgttt aggaattgat tgtccgttga aagtaatcgc tgcttgcaaa tctgttttct
     4201 tcagtctgac ttcaggtctg tatctataac attgggtttc aaggtaagct aaaatatctt
     4261 ctttccattc ggaaaggtga gatttctttc ttttatgacg ttccttctta aatttgtacc
     4321 aagtatttct ttgttgtgta aacatttttt cctcagacag cgattctaag ccccaatttg
     4381 acactaactc ctgtacataa gtcttacttg cacctctata cttcccagag taagcacttt
     4441 ttacaattct tactcgttct ctatctttta gaggacgttc taaagaactg ttaaaaagat
     4501 ccatctcatt tagacagtct tctaagtcaa ctcctgatgc ataattggcc aaagataaag
     4561 tgaaaatcac attattccgg cccataatcc ctttagcgcc tacaattttt ggattactaa
     4621 ttaattgtcg ataccacatt tcgttcactt gtttatattt atttttaaca agtgaaagta
     4681 gcggtttttt atatgttttc gctggctcat atttcattga ccattggatt aattgctgta
     4741 tatcatgtgt taaagctgga taataataga caatgttgtc agttctaggg atacgtgcta
     4801 tcccaaaatg attgcaacct aaatcgactg aaggcaattc ttcagcaaat gcttttctta
     4861 agttctcaga tactcgtttg gccacttcga ttgactgata attatttttg gacgaaatat
     4921 accaggcatt ttcaagaata aagtatgctt ggaagccccc tggtgtttcc aaaataaggg
     4981 ttggcattaa ttccagatcg attgctgcat cgagaatcat ttgagaatct aatttttcgc
     5041 ctgttaagcg atcaaaatcg attacaaaag tattgatttg ttgcaagttg cgttcgttgt
     5101 gcccttttac aattattctt ttttcatctg catatgcacc atagctgtaa acgttaggtg
     5161 tccaatgagt aaatttatct tcattttcag ctaagccttc ttgagaagta agaacgattc
     5221 cacgagattc cgtcattaac ttcttggatc taaacccaaa aatagcacct ttttttcctt
     5281 cagctttata gccgattggt ttaattttgc tgtttaaaca cttgtattca cgaataccac
     5341 tttttaaaat aactgaaatc acgtcagaaa ctttcatctt atcaccaccc attctatatt
     5401 taaaaaaagg agaactgcag gcattctaca gctctccttt aaaccttatt tgcagctaaa
     5461 atatagctca aaatcttgat ttttaaggtc ccaaatgata taattaaaaa gactaagaga
     5521 gctgcaactc tctgtaatct aaaactataa tgggacgaaa gagaatcatg aaatgctgtg
     5581 tacattttga ttctgtaatt tagttgatcg gcaaatcaac taagttaccg tctctatttt
     5641 tttgtctata attcaattag taaatgtatc ttttttctat tcattcaaat tcttctttag
     5701 aatacatgtc actacaactt ttgtaaagta aaaattttct ctcaaataat cattcttaat
     5761 ttatttttgt atccttttat ctttgtatcc ttttatcttt ttatcttttt atctttttat
     5821 cctttaattt tattgttgta tctttttatc tttgtatcct tttatctttt tatctttgta
     5881 tccttattta gaagtctatt taataacttt tcttataaaa tgctatctga ttaaataagt
     5941 atgttttaag ataattagaa aaaagataca tttatctatt tacaattaat tctatttgta
     6001 ttactattta aatatagaaa aaagatacaa agatacattt atcttttatt acattttgat
     6061 tacaaggaag gagtatattg atggctaata caattatatt tggacaacaa aagggcgggg
     6121 taggaaaaac aactgacact tgcatgataa cgttggtagc tgcgatgcta atgaaaaagc
     6181 gtactatttt aattgatatt gatttgcaag caaatgcaac aaattttatg acaaaaacat
     6241 ttggggtaga aacggtacct cagactttga tgtctgctct tgaaaatggc gatctacgtc
     6301 ctgctatcgt aaaccttaag gaaaacttag atttaattcc cgctggttat gatatgcgtc
     6361 tatacactga attcttaaca gaaaattttg ataatacaat agatagaact ttttatctta
     6421 aaaaccttat tgaagaaatt aaagacgatt atgattatat ttttattgac atcccacctt
     6481 caaccgattt aaaggtagat aatgctatgg ttgcatgtga ttacttggtt gtagtacaag
     6541 aaacacaaca attttctttt gagggaagtc aacggctaat ttttgattat atacaaacct
     6601 tagttgacga ttttggctca gacgttccaa ttcaaattgc aggcatttta cctgcattgt
     6661 tacaacaaaa acgcccaatg caccaaaaat tagttgagga aacaatagac acatttggaa
     6721 gagacaatgt ttttaacact attattcaaa atcatgcacg tttagagtgg tatccacgga
     6781 ttggatttca atttcaagac tatcatgata aaaaaatgat tgctcttttt gcagatattt
     6841 tctgtgaatt agaagaacgc atcactcttt ataaaagtaa tggtgatatt caagattatt
     6901 tttatactcc gagatatata ttagacggaa aattaacttc cctgggaaag gagattagtc
     6961 taaatgtcta gtttgataaa tcgtaaaatc ccacaagggg caacagcaaa taaagaagca
     7021 gatacaaaac gaaaagttac tattcaaaaa aaatcgagta aaaagatatt agcttcagaa
     7081 agaaaaaaca tcaaagtgtc cccctctact tttgacttaa ttaaaaccat atcaacaatg
     7141 aaaagctaca aaaattatga atttattgat aaagctgtag aaagctatat acaaaataat
     7201 ttaacagaac gtgaacaacg tatcctcaaa aatttaatct caaaataaat aaaaaaggat
     7261 aaaaagatac atgtatcttt ttatcctttt ttatttattg atttcttttt atcaatgcag
     7321 attttaccat ttttatcaag tagaggcgta attcctcctt taggagtttc taaataattc
     7381 acaccagtaa cagtatcaac tacaatttta tagcctaata gagttaaaga ttcactttct
     7441 ttttcaacaa aacgtttgtc tttaaataca tgttccttac atttatgtct gtctaatggt
     7501 acgttatctg attgttctat caactcacta tttgaattat ccccggcaac catcatgcct
     7561 aaatttttat cataataaat atattctcca cctagtatta aggttaatgg cataaaaatc
     7621 ttcctttctt taattttctt accgtccttt ttctcttttt ttaacggctt tcgttactta
     7681 cctttttgtt cattttctac gcacaatcaa tcgattaaac agattgcctc ttattccaat
     7741 aagtaaattt caagtgcaaa tcatcctatt tttaaatagg atctgttgtc aactttttct
     7801 taattctatc aaaaaacgga agattttgct tgcaaaccaa ttccctttta ctaaattaaa
     7861 ataggttttt atttagtatg aaacagaaac caacattgaa gtaaatctta tttgtttatt
     7921 ctttaattat tgtaattgct acatattctc cttgtttctg tttgtatcgg cgatggcatt
     7981 taggacagta aaagtaattt ttttgataaa cactttttgc taattcccca cagtcacact
     8041 ccacgtgaaa agcaatattt cgattaaaac tagttatttc aatgccccaa cgatcataag
     8101 attttcgctt cataaaaatt ttcctccttg taaattttac taacgattat aaataccgtt
     8161 gccattcttt caactgttga ctaattaacg cataaaattc gacttctgat aaaatggtaa
     8221 tctcatgacc taacgcaatc aagtcccgcg cggtttgttc cttttttgta tagagagaat
     8281 catcaaacaa cgacttagaa tactgaccac aaaccaggaa atttgttttt gaagtaacac
     8341 ttgattgaca atggccgttt aaagagtgaa ccaaaccgat ggcttgggtt cgtgtcattt
     8401 gctgcagcgt tccagtaaaa acgacccttt gattcgttaa gtccattttc aaactctccc
     8461 ttcccgtcta atagctgtta tatctatcaa gaaaagtggt gcaaggtatg ttcatattct
     8521 ttcacccgtc gataaaaggt atttcgtttc atgcccaatt gatccatagc atagactgca
     8581 gttatctttc ctgctttcca gtcagaatag atcgcaggaa attcaggagg taaagcaatt
     8641 ttctttctgc cgaattttac acccttttgt ttcgcagctt ctacgccttc tctttgccgg
     8701 ctattaattc gtttccgctc gtcttcggcc atatagctga gtaattgcag aattaagtca
     8761 gagataagcg tctctaaccc atctagttgc ttgtaactag cagtatctaa cagaggcatg
     8821 tctaacacag aaatatcaat ctgcttttcc ttagttaatt ctcgccattc ttctaaaatc
     8881 atttgtttat ttctgcctag tctatctaat gattgtagat agagtaaatc tccttttcga
     8941 aacatccgtt tcattaattg atattcaggg cgtttaaaat ctttgccgct ggctttttct
     9001 acaaatatat attcttcagg gattcctaat tccttcgcgg aaatcagttg tcgttcgatc
     9061 gattgatcat aactactgac ccggatataa aaaaattttc tcatcgtttt tatctaccct
     9121 tttttcacta aaattgtttc aaaacaatca gattaaatca gaaacgtttc aaattgtatt
     9181 atgtggttat tatgccatac ataaacaaag aaaatcaagg catgtcaaaa agtatacttt
     9241 ttgaaacagt aagtttacac tcccgcatga ttatatttat tccgctaaaa tacataaaaa
     9301 tggcaggcct taacggtctg ccattaaata aactagttat ccagtttttc ttttatgtct
     9361 tccatggtat attttatttt tcacatcaga atttgacttc tttaactttt acaatttttt
     9421 taacactatt attctattac aacactatat atttctaatt tagggttaaa aataaatctt
     9481 tttgatactt ttgcctttac aatataattg tattctttct ttttttcttt gaagtcgctt
     9541 gattcaactg taacttcaaa ccacatttca tttggagact cttttaattt ttttacttga
     9601 aatgaattat ctcttggatc ataaggtggt actctttcaa actcaggaag ttttctctgt
     9661 atttgttctt caggagtatt cgcaaagtaa tctactatct tgacagttat taaaagtact
     9721 actattccca aaactataac aaacataaag ataattccac atccagaatt atttttatta
     9781 ttttgagtca gattattcca ttctatttct tccataatca tcatgtcctt ttacaattca
     9841 tatacttatt ttatcgtata tatttaaaaa ggaaaaggac actgtttaaa tagtaaacga
     9901 ttcttaatta agtttacttc tattttcttg aaattgaata attttttcag aaaatccatt
     9961 tgcaactttc ccctcatctc caataaaatc aagataagta aaatctgtcc caagtgaatt
    10021 attaactatt ttatcaatga aaaatgaaat tatccctaca cctaagatat caactgtttc
    10081 gtcattttct aataaactat ttgttactga agcgatttta tctgaagaac caaatctgtt
    10141 cttaacaaat tgattaaatc tatcaatagc acccttatca caatagtacg tttttaaagc
    10201 cgataaagct gttgaatcag aatttctttt tgctaaggta taaacattta ccgcgtcaac
    10261 atcttggtat aaatcttcta gactaaatgt tccacctgca gccgtaccta ctaatgcaaa
    10321 tacaccttgc tccatttgta ttcctaattt cttaacttca ccccagcaag tcattaaatc
    10381 tcctaaccaa cctgcaaagt cagaaacact atcattgatt gtgtcggcta gaaacatctg
    10441 tgattgtaac gtcacaatta agtgaggcaa acctattatt gaaccagtat taggatctat
    10501 aaaataatta tacaggccct cgctattagt taatttattc ctatattcat cataaatttt
    10561 tctatcatgc tctgttacag gagaagaaat gatgtcccat gacaaaccag aataatttac
    10621 atatctataa aatgtcaaat gagggttcca aggattatca agaccagctt gtgatagata
    10681 ttgatacgca cgtaccatct gatttataac cttctgattg tatttggcaa tgtaattatc
    10741 attattagta tcatttgata actcattaaa tccgctatct ctacccgatg tagcgattaa
    10801 atcgatacca acagctccgt tgccacttcc tatggtaaat tcaacaaatt gatcaaaaga
    10861 ccattgtcta ggcataggaa aacctaaatt cccactataa ccagtcgaca tatctgaaac
    10921 aaatgcaaac gaagcatacc cgttattgat tatttgagaa caaacatttc ttgttccgta
    10981 aacacccgtt tgatacccgc tatatgacat tacagcagat acccccttaa aatattctcc
    11041 agcatatgca agaatttctt cccctaacat gtctagatca acagcaaaat aaataactgt
    11101 tgttaatggt atatttagat tttttgctgc atctatagcc ttcttaccat ctgataagcc
    11161 acgatcataa gtaaaataag ctaatgctgc acctccatct tgatagatag gaaacacaga
    11221 taaattttta gaaaaaatat tattcaattc ctctgtagtt agatacttat ttcgttcatc
    11281 ttttccaatt ccaacagtac cagtaagata tctaccaact atttttatat cattatcaac
    11341 caatgtttgg atttgagatc tagttaattg cgtagaagta tctgcgccat ctgcagatct
    11401 tctaatatct ccagcgctag acaatagtcc ttttattaca acaacatctg ctatttcagt
    11461 atattcaggc aataccataa attttcggaa tgccagtact tctaaaccca tatatttagt
    11521 gaaaatacca tcgaatgtac cgtcttcaaa ataaccatta acatataatc catattgaat
    11581 tattcttaca tagtttcccg agttaccttc agacacagga taagttttac tagttgtccc
    11641 attaccataa gaccctgttg cttcactggg agaatatcct agttcagctt gtaatgcaaa
    11701 aattaatgct tgatttgaat ttctttgata aataccatca caaggcatta ttcccgtgta
    11761 ttctaaataa tttacattta accattgctg catttttcta attttactat ctccgccggg
    11821 aacaagaaca aaagcactca tatcaaataa cgctttggcc catttcgcat ccaaaactcc
    11881 agttacagcg cttccattaa accctgcatc agtctgcaac tcttttacag cagtatctaa
    11941 atatggagta tataccccat cgaagccacc tggattaatc cccttacacc aaaaggcacc
    12001 ttgaataaga aatacaatat ttttaggtag atttttgccc catttaggag taacctgatt
    12061 atcgtacatt ttttcagtgg taggtccaaa attagctact agattagtaa taccaagttc
    12121 tacttgtagt ccttcaataa gtccatagat tgtaggccac cctgttcgcc cattttctgg
    12181 aaccttatca aaccctgtaa cattactgta tttcttgttt agccatttct gagtacttaa
    12241 aaccatctca tccataaaaa tcccctgctt tcttgccgaa catacgttcg tttatgtgtt
    12301 gatt
//
LOCUS       DACCVH010000084        12144 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.084, whole genome shotgun sequence.
ACCESSION   DACCVH010000084 DACCVH010000000
VERSION     DACCVH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.084"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..566
                     /locus_tag="IVV98_002357"
     CDS             <1..566
                     /locus_tag="IVV98_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP7807957.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="IVV98_002358"
     CDS             967..1572
                     /locus_tag="IVV98_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAP7807958.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="IVV98_002359"
     CDS             1588..2160
                     /locus_tag="IVV98_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7807959.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="IVV98_002360"
     CDS             complement(2412..2669)
                     /locus_tag="IVV98_002360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807960.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="IVV98_002361"
     CDS             complement(2795..3610)
                     /locus_tag="IVV98_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807961.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="IVV98_002362"
     CDS             4127..5452
                     /locus_tag="IVV98_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP7807962.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="IVV98_002363"
     CDS             5445..5795
                     /locus_tag="IVV98_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807963.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            complement(6866..7141)
                     /locus_tag="IVV98_002364"
     CDS             complement(6866..7141)
                     /locus_tag="IVV98_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAP7807964.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="IVV98_002365"
     CDS             complement(7113..8066)
                     /locus_tag="IVV98_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7807965.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="IVV98_002366"
     CDS             8678..10171
                     /locus_tag="IVV98_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAP7807966.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="IVV98_002367"
     CDS             10306..10602
                     /locus_tag="IVV98_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP7807967.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="IVV98_002368"
     CDS             10703..11554
                     /locus_tag="IVV98_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807968.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="IVV98_002369"
     CDS             11575..11787
                     /locus_tag="IVV98_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807969.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4171 a         1864 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca cctggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DACCVH010000085        12124 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.085, whole genome shotgun sequence.
ACCESSION   DACCVH010000085 DACCVH010000000
VERSION     DACCVH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.085"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(16..573)
                     /gene="frr"
                     /locus_tag="IVV98_002370"
     CDS             complement(16..573)
                     /gene="frr"
                     /locus_tag="IVV98_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP7807970.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(576..1298)
                     /locus_tag="IVV98_002371"
     CDS             complement(576..1298)
                     /locus_tag="IVV98_002371"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP7807971.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1434..2315)
                     /locus_tag="IVV98_002372"
     CDS             complement(1434..2315)
                     /locus_tag="IVV98_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP7807972.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2414..3196)
                     /gene="rpsB"
                     /locus_tag="IVV98_002373"
     CDS             complement(2414..3196)
                     /gene="rpsB"
                     /locus_tag="IVV98_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP7807973.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3555..4034
                     /locus_tag="IVV98_002374"
     CDS             3555..4034
                     /locus_tag="IVV98_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP7807974.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4251..5342
                     /gene="phnW"
                     /locus_tag="IVV98_002375"
     CDS             4251..5342
                     /gene="phnW"
                     /locus_tag="IVV98_002375"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP7807975.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5335..5463
                     /locus_tag="IVV98_002376"
     CDS             5335..5463
                     /locus_tag="IVV98_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP7807976.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5467..6012
                     /locus_tag="IVV98_002377"
     CDS             5467..6012
                     /locus_tag="IVV98_002377"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP7807977.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6466..8157)
                     /locus_tag="IVV98_002378"
     CDS             complement(6466..8157)
                     /locus_tag="IVV98_002378"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP7807978.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8577..9524)
                     /gene="arcC"
                     /locus_tag="IVV98_002379"
     CDS             complement(8577..9524)
                     /gene="arcC"
                     /locus_tag="IVV98_002379"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP7807979.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9639..10658)
                     /gene="argF"
                     /locus_tag="IVV98_002380"
     CDS             complement(9639..10658)
                     /gene="argF"
                     /locus_tag="IVV98_002380"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP7807980.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10749..11978)
                     /gene="arcA"
                     /locus_tag="IVV98_002381"
     CDS             complement(10749..11978)
                     /gene="arcA"
                     /locus_tag="IVV98_002381"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP7807981.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3310 a         2518 c         2194 g         4102 t
ORIGIN      
        1 gtttttatga ttttattaaa cttccaataa ttctttttct ttatcagcag cgatcttatc
       61 tacttctttg atgctgttat ctgtcaatgt ttgtacgtct ttttctaatc cgcgcaaatc
      121 atcttcggta atatcaccat ttttttgttg ttttttatat tcatcgatcg catcacgacg
      181 gatgttacga atcgcgattt ttgcattttc tgcttctttt ttaacatctt tagctaattc
      241 ttttctgcgt tcttctgtca gttgcgggat aactaagcga atgacatttc catcattggt
      301 tggactgatt ccgatatcac ttgccataat agctttttca acatcttgaa gaatgctctt
      361 gtcaaaaggt gtgatcatta aaacacgtgc ttctggaatt tggattgatg ccatttggtt
      421 caatggtgtt ggcgcaccgt agtagttcac agtaatacgg tccaaaaggc tagcgttcgc
      481 acggcctgcg cggatttgcc caagttcacg ttgaagattt tgtgctgctt ttttcatttt
      541 ttcttttgct tctgtcataa ttgcatctgc catttttatt tcccccttac agttgttccg
      601 atattttcgc ctaagattgc acggcgaata tttccgtgtt catttaaatt gaagacaagc
      661 agtggaatat cattatccat gcttagtgaa cttgcagttg aatccatgac ttgtaatcct
      721 ttggcaataa cttccagatg agtcagttct tcaaatttta ctgcatttgc atctactttc
      781 ggatcagcag aataaacacc gtctacattg tttttagcca tcaggataac atctgcgccg
      841 atttctgccg cgcgtaatgc tgctgttgtg tctgtcgaga agtacgggtt gccggtaccg
      901 cctgcaaaga taacgatccg tcctttttct aaatgacgtt ctgctttacg gcgaatatat
      961 ggctctgcga tttgacgcat ttcaatcgaa gtttgcacgc gtgtcggtac acccacgttt
     1021 tccaacgtat cctgtaaagc taaggcattc ataactgtag ctaacatacc catgtaatca
     1081 gcttgagcac gttccatgcc catttgtgct ccgatttgtc cgcgccagat atttccgccg
     1141 cccacaacga ttgccatttc aacgcccagc tcgtgaactt ctttgatttc ttggatgatt
     1201 tctttgatta ctggtggttt gattccaaat cctgcgtccc cagctaaagc ttctccactc
     1261 aattttaaga ctacacgctg atatttcggt gtgaccatgt tcattcctcc aatattttct
     1321 attgccattt taccatactt agatgatttc gacactctaa gactggtttt tcttgttttg
     1381 cttaaaaaaa gggagcgcac aaaccgtgcg ttcccgtctg ttattcaaca gaattatttt
     1441 ttcacttggc tcataacttc ttctacaaag ttatcttcgc gtttttcgat accttcgcca
     1501 acttcgaaac gtacgaatgt tttaacagtt gcgccttttg atgcaacgta tttttcaaca
     1561 gtcatatcag gatctttaac gaatggttgg tccaccaaag cgatttctgc tttgaatttc
     1621 ttcaagcgtc cttctaccat tttttcaacg atattcgctg gtttgccttc gttcaatgct
     1681 tgttctgtaa gaacagtttt ttcatgttct aattcagctt ctggaatttg tgattcgttt
     1741 acataacgag gattgatagc tgctacgtgc atagctacgt ctcttgcaac tgtttcgtca
     1801 gttgttccat ctagaacagt caatacggca atacgtccgc ccatatgcaa gtatccacca
     1861 aatgcagcat tgtcgtcttt ttctacaact tcaaagcgac ggaagctgat tttttctccg
     1921 ataacttgag ttgcttcgat caagtcagat tcaattgtac ctttatctgt tttgattttc
     1981 attgcagctt ccatgtctgc tggtttgttt tcagcaacaa gttctgcaat ttcttttact
     2041 aaatcttgga acatttcgtt tttagaaaca aagtctgttt ctgagtttac ttcaacgatt
     2101 gctgcagtgt tacctttcac agcaactgaa gccaatcctt cagctgcaat gcggtcattt
     2161 ttcttcgcag cctttgccat tcctttttca cgtaaaagat caactgcttt ttccatgtcg
     2221 ccttctactt caactaatgc ttttttcgca tccatcattc ctacgccagt catttcgcgt
     2281 agttctttta ccattttagc tgtaacgtct gccatgttta actcctcctg tgtgtttttc
     2341 tttttaaaaa aagctgcttc aaaggagagt gaggcttgtc gcccagcctt tgaaacagct
     2401 ccatcattca aaattattct gctgaagaat tgtcgccttc aacaacatct acgatttctt
     2461 cgattgatgt tgctgtgttt tcttctgtga aatcttcttc aactacttga tcttcacctt
     2521 ggtttccttc gatgaaagca tcagccattt ttgaagtaat caatttaacg gcacgaattg
     2581 catcgtcgtt tgaagggatt actacgtcga tttcatctgg atcgcagttt gtatcaacca
     2641 tagctacgat tgggatattt aatttgtgtg cttcttgaac agcaatacgt tctttacgtg
     2701 ggtcaacgat gtacattaca tctgggattc ttggcatatc agcgataccg cctaagaatt
     2761 tttcaagacg ttcacgttct ttgttcaaac cagcaacttc ttttttaggt agaacttcaa
     2821 aagttccatc ttcttccatt gcattgattt gtttcaaacg gctgatacgt ttttggatag
     2881 tatcccagtt tgtcaatgtt ccgcctaacc aacgatggtt aacgaagtat tgtcctgcac
     2941 gagttgcttc ttctttgatt gcttcttgtg cttgtttttt tgtacctacg aataatgcta
     3001 cgccgccttc ttcagcaacg ctcttcatgt aatcataagc tgcatctact aatttaactg
     3061 ttttttgcaa gtcaatgatg tagattccgt ttctttctgt gaagatatat ttcttcattt
     3121 ttggattcca gcgacgagtt tggtgaccaa agtgtacgcc ggcttctagt aattgtttca
     3181 tagaaattac tgccatgttt gtttcctccg atttggtttt atttttcctc ttcttatctt
     3241 ctaccttgcc ggcaaacttt ttcaagcacc taccgacaat ccaataagaa tgtggatttg
     3301 ctgatgcata aagcaccctc agctattata cagacaaaag atccgtatcg caagagcaaa
     3361 tatacttttc tgctcaacat tcaatagttt acctgaaaga taaaaagaat tcaagaaaaa
     3421 cagtagattt ctctttgttt ctttattatc ctttttccat aaaataattt taggtataaa
     3481 agacgaatat tattgggcaa tccttctttt ttttgttatg atacatgtga aatctttcgt
     3541 aaaggagaaa gaaaatgcgc aaagctcaaa gacatttgct gattaaacaa gtcattgaag
     3601 aattcccgat ccgtacgcaa gaagaactat taaacaaact tgggcattat ggcgttaccg
     3661 ccacgcaggc aacgatttct cgagatatcc gtgatctaaa aatcgtgaag gcacctgatg
     3721 aaaatggcgt ttcccgcttc gtattgtttc gcgaaaaagg aactcctgag actaggactg
     3781 aggaagagga tcggctggtt caaatgattg aagacattgt attgaaagtc gaacgagtcc
     3841 actttttgac gatcgtcaat accttgccag acaatgctca tttatttgca tctgttttag
     3901 atgagatcaa acctccctct attgtcagta caattgctgg attcgatacg atcatggtca
     3961 tctcggaaaa tgaggaggac gcaaaacgag tagaagaatt tcttcaccat ccaactgaag
     4021 tatcactttt ttaatcagag cacgtattcc taatatggaa tgcgtgtttt tttattttca
     4081 atattttcct tattgaataa acctttacac tctttacaaa aatacatcat tttttattca
     4141 aatttttcaa caccttgatt gaatcacaat aatcatcatt tatattggat gttaacaaga
     4201 gcagcttctt gctctttgtg tatttcaaaa aagaaatgaa aggaaatcat atgtataaat
     4261 tattaacttc tggaccattg acgacttctg aaacagtgaa aaatgctatg ctgatcgatc
     4321 attgtacttg ggatcaagaa tacaaagaaa ttacacaatg gataagaaaa aaattattgg
     4381 atcttgctca agtatcggaa ggaatataca caacggtctt aatgcaaggt agcagctcct
     4441 tcggggtaga atcggtatta agttctgtga tcaggccaga agatactgta ctgatttgtt
     4501 caaacggcgc atatagacaa cgaatgatca acatgtgcga atgtctgaaa ctgaactata
     4561 ccgtttatga ggtatcggaa catcaaatcc tccaagctca tgtgattaca cagctgattg
     4621 aagagaatcc gtctatctcc gcactagcaa tggtccatag cgagactact tccggtattt
     4681 tgaataattt ggaagagatt gctgctgtca cacaagaaag agatcttttg tttatagtgg
     4741 acgcgatgtc aagctttggt gggataccga tttgtgtagc cgaactaggg attgattttt
     4801 tgatttccag ctcaaacaaa tgtattcaag gtgttccagg cttttctttt gtacttgcta
     4861 ataaagcgga actggaaaaa cgaaaaaatg ttagccgaag tttgtcactt gatctatatg
     4921 accagtaccg cgtgatggaa aacgagaatg gcaaatggcg tttcacttcc cctacccata
     4981 cggttttggc ttttcaacaa gcgctgaagg aactagaggc agaaggagga atcgaaactc
     5041 gatattcacg ttatctcgcc aataatcatg tgctacgaca aaaaatgaca gagatggggt
     5101 tccagccttt cattcaagaa tatcaggggc cattcatcac ctcttttctt taccctaagg
     5161 actggcgatt tgattttaat catttttatc agtatttaaa gcaaaatgga tttgtgatct
     5221 atcccgggaa aatcagcgat catgaatgtt ttcgtatcgg aaatattggc gagatctatc
     5281 cggaagatat tttggaactg acagcaatta tcaaagacta taaggagaac gttaatgatt
     5341 aaaactgtaa tttttgattg ggcaggaaca actgtggact ttggctgtat ggctcctgtc
     5401 cacgctttta gaaatgcttt tctagaaaaa ggaatccaac tgactgacaa agaaatccgc
     5461 taaccgatgg gaaaattaaa atgggatcat atccaacagc ttctttccct cccttctgtc
     5521 aaaaaacaat ggatagctat ttatggacaa ctacctcagg aaaaagaggt ggaggaattg
     5581 tatcaacaat ttgaacatta tctgtttaaa gatttggtca agcattctac cttgaaaccc
     5641 gacacattgg aaacgatcga acggttgaga aacgctggga tcaatattgg ttccacgaat
     5701 ggatttaatg ctcctatgat gacaatcgta gcagaaaccg caaaaaaaga aaggtattca
     5761 ccagacttca tggcaacttt tgaagacgtc gaagggtatg gtcgaccgtt tccttatatg
     5821 atccataaaa acatgcagta cttcaaaaac aagtcggttg atgaagtaat caaagtcgga
     5881 gatacggtct cagatatcca ggaagggaaa aatgccggag tgttgacagt aggtgtaatt
     5941 gaaggtagtt cgctaatggg gatttcttat gatgagtacc aaaaattaga gatggggaaa
     6001 aagatcgttt aaaacagtct gttgctctta gattccaaca agccggcgct gatatttgtg
     6061 taaacaattt aaaagagtta acagaataca ttttgtacgc tgacatgaat ccagaatgac
     6121 ttttatacaa aataagaggt tgtgaaaaag ctgtcctgta tcaagtaata aaaacagcca
     6181 agcaaaaata gctcctcata tttttcgttt ggttaggctt attaccgcag atgcaagctt
     6241 ttgaacaccg tttattcgaa aaaaaaaagg gagctgtgac acgacttttg tcacagtccc
     6301 cttatttgca aacaaacagt gtttaagaga caacctctcc actaaacggt gttcattcag
     6361 ctgactctcg gtatttgctc aaaaaacgat aaaatttgaa aagctatttt ctcttttgtt
     6421 tctctaatac tcggatcaga acgctgattt cacattctct ttttcttaca tcttatctgg
     6481 tgcatgaagt cctagcaaac gaaggtcttc tttcaataat acagtcactg cataaactag
     6541 agctaagcgt gcttcttttt gttcatcatc agctaaaatc ttcgtatgag catagtattt
     6601 gttgaatgct tgtgctaatt tgattgcatg tttcgcaatc actgacggtt cgtatttttc
     6661 cccagcagac aagaccgttt cagggtattt ttgaactaat ttaaccactt cccagctggt
     6721 atcgtcattc aatgcatagt ctgctgtttc tgaagggaca aatcctgctt tttccaacag
     6781 gctgactgca cgagcatgtg tatattgcac ataaggtcca gtttctcctt caaatcgaac
     6841 aacttcttcc aggttaaagt caaatgtatt cagtcgatcg tttttcaaat cgtggaaaat
     6901 gactgcccca accccaactt gtttagctac agcatctttg ttttccaaat cagggttttt
     6961 ctcgctgatt tgttctttag cagattggat tgcttcattt aatacttctt ctaataagac
     7021 gatctttcct ttacgagttg ataatttttt accaccttgc gtgatcaaac caaatggaat
     7081 atggtgcatg tcgtcagacc agtcaaagcc catttccttc aagacagctt tcaactgttt
     7141 aaaatgatag ctttgttcat tccctactac atatagagat tgtttgaagt cgtaagtacg
     7201 tttacggtac aatgcagcag ctaagtcacg tgtaatgtat agtgtcgcac cgtctgactt
     7261 cttaatcaac gctggattca ggtcataagc agataggtca acgatctctg cacctttatc
     7321 ctcgttcagc aaatgttttt cttctaaaag tttgacgatt tcatccatct tgtcattgta
     7381 gaaagcttca ccgttcaacg aatcgaaacg tacttccagc agatcataga ttttattgaa
     7441 ttctttcatc gattcatcac ggaaccattg ccataattga atagcctctt tatcgccttc
     7501 ttccagacgt ttgaaccaag cacgagcttc ttcatttaat tctggttctg tttcagctac
     7561 ttcatggaat tggacgtata aacgaagcaa ttcattgatt ggttctgctt taacagcttc
     7621 ttctgtaccc cattttttgt aagcgacgat cagttttcca aactgtgttc cccagtcacc
     7681 taaatggttg atgcggattg gctgataacc gattttttcc ataatgaaac cgatcgaatt
     7741 accgataact gtcgaacgca aatgtcccat tgagattggt ttggcaatat taggagaaga
     7801 catgtcgatt ggtactgttc cttgattccc gatgttgcta tccccataat gttctttttc
     7861 tttcactact gtttgcaaaa cttttttgct gataagttct ttattcatga aaaagttcaa
     7921 gtaaggtccg acaacttcga ttttttcaaa gttggcagaa tcgatttttt ctgctaaatc
     7981 tgcagcgatt tgctgtggcg cttttcggta aacttttgct aatgaaaagg ctggaaatgc
     8041 aacatctccg tgttcagctg attttggatt ttctagtaat tgctcgactt gttccagtgt
     8101 taaatcatct ttgacagcgt catagacagc ttttgcgaca agatctttat tattcatctt
     8161 tattcctcct aaagtgttcc cttgattgtt aaacaaaaaa aatctctagc gacggcatac
     8221 ttagtatgcc atcactagag acgagatttc ccgcggtacc actccaattg tcctaaaaaa
     8281 ggaccagctc catctgatat cggtagacga ccgtctgttt aaaacagaat tctccaagtg
     8341 cgcttcgttg tatcttcttc attcggcttc caccacttcc gaattcgcta gccaagaatg
     8401 atacaagtac tctcttgttc aacaaatctt agtcttatta aactttcttg aattatatca
     8461 gaaaaaaaaa cgaaaggcta gtcgtttcat aaaaaaacaa tccagatggc ctaaaggaga
     8521 agaaatacca cctggatagc tataaatcat ttcgtaaata cgaaagactt aacaaattaa
     8581 tcagctacga taatcgttcc ttcttcagaa gctaaaagat tctcgatatt ttctaaagaa
     8641 gtgatgattg ccttagcgtt tggttttgct tcaacaaatg caatagctgc ttctactttc
     8701 ggaagcatgc ttcctggagc gaattgcttt tcatcaatgt attgtttcat ttctgaaaca
     8761 gtaacagttt ctaatttctt ttgatctggt ttttggtaat tgacatacac attgtctact
     8821 cctgtcaata cgatcagcaa atccgcatcg atgatttcgg ctaatttttc tgaagcaaaa
     8881 tctttatcga ttacggcttc tcgtccttct aatccagtag ctgtttctac aacaggaatc
     8941 ccaccgccac caacagagac tgtgataact ccttgatcga ccagcgtttc gatgacacgt
     9001 gcttctttaa tcgagatggg tttaggggaa gcgactactt ttctccatcc acgtccagca
     9061 tcttctttga atgtcacagt ggagtcagca ttcatttgtt ctttggcttc ttcttccgtg
     9121 tagaatggac cgactggttt acttggattt ttgaatgaag gatcattttc atccacaata
     9181 acttgagtga ctaaagaaac cacatcttta tcgatccctt tttccttcag tacttcgccc
     9241 atggcgtttt gtaaccagta accgatagat ccttctgtca ttgcaacaca tgtatctaaa
     9301 ggcattgccg gtgttttctc agaatcagca gcttgctgct gaatcaatag gttaccgact
     9361 tgcggaccat ttccgtggga gatgatcaat tcatctcctt gttcgataaa tttcactaaa
     9421 tactttgctg tttccattaa cgcttcttgt tgggcttttg cacttgcatc cgtagacaag
     9481 atggcattgc cccctaaagc gacaactact tttcgtttgg ccatttcatt cgtcctttct
     9541 tcagttctac cgaattttct agataacaaa acgagccagc gttttgtgat tttccctcaa
     9601 tgctgactcg ttttttcgtg agatgaatgt ggttatgctt aaacgcgagg gataaacaag
     9661 ttacctaatg ttgctgccat gatcgctttg attgagtgca tacgattttc tgcttggtca
     9721 aattgacgag catatttgct gcggaagact tcatctgtta cttccatttc agtgatgcca
     9781 aagcgttctt tcatttgttc accgtaaaca gtgtttgtat catggaaagc tggcaagcag
     9841 tgcaagaaga tcaaacgatc tgtgttgtgt gttttttcta ccatttccat attgatttgg
     9901 taaggtttca acaatttgat acgttcttcg aatttatctt cttcacccat tgatacccat
     9961 acatcagaat aaaggacgtc tgctccgtct acacctttat caacatcgtc ggtaatcatc
    10021 aattgtgcac cggatttttc agcaaagcct tctgccattt tgacgatttc ttcttcaggt
    10081 tgtaattctt ttggtgcaac gatacgcata ttcgctccta aaattgcacc tgtgactaat
    10141 aaagagttag ccatattgtt tcgaccatct ccgcagtaag caacagtgat accttctact
    10201 gttccaaagt tttcttggat agttaaaaag tcagcgatca tttgtgttgg atgccattca
    10261 tcagtcaagc cattccaaac tggaacacca gagaattctg ctagttcctc taccattttt
    10321 tgactgaatc cacggaattc gattccgtca aacatacgtc ctagtacttt agctgtatct
    10381 tctgtggatt cttttttacc taattggata tcatttgcac ctagatattc aggatgtgca
    10441 cctagatcga tcgctgcagt agtaaatgca gaacgagtac gtgtagatgt tttttcaaat
    10501 aaaagcgcaa tattttttcc ttctagatag tgatgtggga taccacgttt tttcaagtct
    10561 ttcaagtgtt ctgaaaaatc gatcaaatat tgtaattctt cttttgtaaa gtctttttct
    10621 gctaataagc ttcttccttg gaatactgat tctttcatat taaacattct cctttagatt
    10681 gtttttattt aagattaaag aggaaatccc gacggcagct gacagtaaga ctgccgtcag
    10741 gaaacaaatt acttcaagtc ttcacggaca agtggttggc tcatgcagcg tggaccacca
    10801 cgacctcgtg acaattcact tgaattgatt tctaacactt tgatgccata gctacgaagc
    10861 aattcgttcg atacataatt tcggttataa gtgactacaa cacctggagc gattgccaat
    10921 gtgtttgatc catcattcca ttgttctcga ggtgcaacga tctcatctcc attaccagtt
    10981 gggatcagta caagatcatc taatccaaga gcagctttca tcgtttcgtg taagttatct
    11041 gaatgagtaa tcttgatatc atcaccatct ggttcgattg taaagacatc catcttaccg
    11101 tctttacttt gaattgctgg atggatagtg aatttatcgt gatctaccat tgtaaatacg
    11161 gtatccaaat gcatcattgc acggttgttc ggaattttga ttgccaacac tttttcaaat
    11221 cctgaatttt ttgcgaatag gtggcgtgct aatttttcta aagctttcgc attagttcgt
    11281 tgagaaatcc caacagctac tactttatcg cttaagatca attcgtctcc gccttcgata
    11341 tgatctggat tttcacgatc caaccatact tcgattcctt tatttgcaaa tcttggatga
    11401 tgtttcaaaa tatattctgt aaacatcgat tcacgacgac gtgcttcaaa agtcatctta
    11461 ttgactgtca tcccatttcc cattgatgcg gaagggtcgc gtgtaaagta caagtttggc
    11521 attgggtcca tgtaaaatgg atagtcatcg tctgctgaca gatcatatag actgctagaa
    11581 cgtacttcga tatcttttgt acgaacccca gccatgattt tatctaccat ttcttgcgtt
    11641 tccattgata gaaggaactc atgaagaccc tctcttacag cattcgatgc aatatgagat
    11701 tcatccaaca ttttattcaa gaattgttct ttgacattgc ctgcgtcaat cgcttctgcc
    11761 gctaattttt ccaagtaaag agtctcgacg ccttcatttt gcaatgtctt cgcaaagttg
    11821 tcatgttctt cttgagcaat cggaagatat ggaatatcat cgaacaacag acgatccata
    11881 atatctggtg tcaaattttc cacttcttgt ccaggccgtt tcagtaaaac tgtctttaat
    11941 ttccctattt cagagaaaac gtgaataggt ttatccatgt tgtgttgcct ccttcttttt
    12001 gattacatgt ataggatatc ctccttttgt aatcactttc ataattttgt ctcattcaaa
    12061 atgagacatt cctcacatta atattcgata attaaataat taaacgtttt tctattttta
    12121 agcg
//
LOCUS       DACCVH010000086        11738 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.086, whole genome shotgun sequence.
ACCESSION   DACCVH010000086 DACCVH010000000
VERSION     DACCVH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.086"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..216)
                     /locus_tag="IVV98_002382"
                     /pseudo
     CDS             complement(1..216)
                     /locus_tag="IVV98_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(470..2105)
                     /locus_tag="IVV98_002383"
                     /pseudo
     CDS             complement(470..2105)
                     /locus_tag="IVV98_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2544..3413)
                     /locus_tag="IVV98_002384"
     CDS             complement(2544..3413)
                     /locus_tag="IVV98_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7807982.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(3433..4554)
                     /locus_tag="IVV98_002385"
     CDS             complement(3433..4554)
                     /locus_tag="IVV98_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP7807983.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(4556..4951)
                     /locus_tag="IVV98_002386"
     CDS             complement(4556..4951)
                     /locus_tag="IVV98_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP7807984.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(4970..5767)
                     /locus_tag="IVV98_002387"
     CDS             complement(4970..5767)
                     /locus_tag="IVV98_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7807985.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(5769..6557)
                     /locus_tag="IVV98_002388"
     CDS             complement(5769..6557)
                     /locus_tag="IVV98_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7807986.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(6571..7047)
                     /locus_tag="IVV98_002389"
     CDS             complement(6571..7047)
                     /locus_tag="IVV98_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807987.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(7119..9776)
                     /locus_tag="IVV98_002390"
     CDS             complement(7119..9776)
                     /locus_tag="IVV98_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7807988.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(9795..10199)
                     /locus_tag="IVV98_002391"
     CDS             complement(9795..10199)
                     /locus_tag="IVV98_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAP7807989.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(10431..10688)
                     /locus_tag="IVV98_002392"
     CDS             complement(10431..10688)
                     /locus_tag="IVV98_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAP7807990.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(10813..11145)
                     /locus_tag="IVV98_002393"
     CDS             complement(10813..11145)
                     /locus_tag="IVV98_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807991.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         3742 a         2307 c         1685 g         4004 t
ORIGIN      
        1 atgtttggct ttatatcctt cgtaatcctt actgttgata attgctttca tattaggaat
       61 tggatcttca cctggcatat attgcagatt agaagcatgt aattttttct cagaaacaaa
      121 ccactcattg gaaaagacat gaatcaaatc atcacttact tgtgtaaaat agcgacgttt
      181 aatgacaaag atatcttcat tgctatctag tgtaccttca tttctttgtg cttaaattca
      241 aagataattt tctcaataaa gatttttgat tccagtaaga ttcctttact ccttttacaa
      301 catagcgttg tcctttgttt tgaaacatct tcttcccctc tttgccatta aaaatagccc
      361 aattctctat aaagaagatt aagcttcatt attataatat aaagtttaaa tttggtttat
      421 tacttacttt ttcttattct ctagtaagct aatattgaaa aaaatgtaat cagatcatta
      481 tttttatatg ttgtaacttc ctgataagaa aactaattaa aagaaagagg taactacata
      541 aactaattaa aaaagctaac ttcatagttg gaggataaat ggaagaaact tcaatgattg
      601 tttctccttg tgttccttca atcgacacta gtcctattat caatctctct tttttgtcca
      661 tttacttttg cgactgttcc ccaataatca aatacaggaa gcgttatttt ttgtccttta
      721 gattcatgta ctgtatagac tattttcgaa tccatcactt gataaggcat agtatgccat
      781 tccttgccaa ttcttacttc atgattctgc aaatgttctt tgtattgtaa tgcttccgtg
      841 ggtgcatagt cataaagtcc tccgggaagg agtgtcgtgt aacgaataag attttcttga
      901 ttcattacca agtgatctct ctgagtgaca actttatgtt catagtttgc ttttgttgca
      961 gcagatacag ccaacagtaa taaaacaatt gccgttatat taactacttt tctttgctta
     1021 gctgatgtgc tcttcatgaa aacgaacgat aaaatcaacg agccaaacag tacttgaaag
     1081 cctaagattc gccaaggaaa ttgaatcatt tgaatgggtg tattttgtaa taaagaccat
     1141 ggaaaaaatt tggtggataa gagccaagag actaccgcac taaggtaaat cactttttct
     1201 ttgcgattaa atcctttaaa aaagaagagt ggacagatca aagaaataat accaatgatt
     1261 cctaccgtaa aggttgtcag gtcattattc atcgcaccaa tcaaactatc cgagacattt
     1321 aatgcttggt gttgtaaggt cgttttatct ggctcattaa tcgattgaac catgatttgt
     1381 cggaacatcg gataccaaaa gtatgctgtt aaaagaatcg tcattcctac tgcctttgac
     1441 aactccacaa tcaaccggat gctttctttt tttcttgttt cacttactac aaagccgcct
     1501 aagactagta agccaacggc tattacactc ataaaagtgg aaagaacatg tgtataaatg
     1561 agtaagctca tactgactgc taatggaatt gcacatggct ttttctcata aatcagtgcg
     1621 taagcataat acataactat cggtataacc gtaagtgcaa tcgcttcagc aatagcagaa
     1681 cgatgataaa tatcaatcgt acggtaccca taaaatgtat ataaacagct aaatataaaa
     1741 gccgcatcga ttctttttaa aaattttagt ccataatgaa acatcagcat gatagtacaa
     1801 acattcaata gccaaacata taagatataa ctaacgatta aattattact tatccaataa
     1861 aaaatgactg ccggaaaaaa ggtcaagtag ggataaaaat aattcactcc gctcccataa
     1921 tgattaaacg tcgtaaaatt gattggacca gaaaaaattg aagataaccc tttgactcta
     1981 gcaaaatgga aggcaatatc ccccgatgta gaaatagtat gaacatttct aaaataattg
     2041 attgaataaa gtccagcaat aattgctagg agaatggaca atattatttt tttctttact
     2101 tgcattactt aattatatac tcctttcatg gattgcttta tctagtataa cttaaatttt
     2161 aaataaatcg ttatttattt ttactctcac ttaaaaaagc actaaaatta taagagaggg
     2221 aggtaatggt ctgaacacca agaattgttc caacatcgaa ttgcttaact aatgagttca
     2281 aagcttaatt atgtggctct tatatttacc gagcgtggat tgcgatctct ttagcgaaac
     2341 aaacatcttt cataaaaaaa acagccatat ccgctttctt ggatatgact atttactact
     2401 actttactat ctttcattct tcttgtctca cttatgataa ggcgctgggt atcatgagtg
     2461 aatgatattg ctgaatacaa atagtccgac cacattaagt tgatcggact tcataagcat
     2521 tttattgact aatacttttt tgcttaagaa ttgattctaa catcttttgc taaagttaag
     2581 catcctatag ttcctgcatt atctgctaac ttaggtgtga caatgtattc ttcgatattt
     2641 ggcgtatcga catagccgtt aattagttct aaaaaacgtc tttgtacttt ctttttcaga
     2701 tgttcttgtt gcatgacacc accaccaaaa attataatat ctggtgaaag catcagggtc
     2761 gtattacagg cacattgtgc aatataatcc gcctcgattt cccagaacgg atcttctata
     2821 gaaagatctt gtcccttggt tcccgtacgc atctcgatag cgggtccaga tgccaaccct
     2881 tcgagacaat catgatgaaa aggacaagta ccagagaaag tatctcctga atgtctctta
     2941 actaacgtat gccccatttc tggatggcta aacccttcaa caaaaatccc atcttgtata
     3001 gctcctccac caattccagt tccaacagtg taataaacaa cactggataa accttttcca
     3061 tgacctgaaa catactcccc gtaacaagca gcattcacat cggttgtcca ggcaattgga
     3121 atttcgaaat gcttattcaa cgttccaaca aaatcaaaat ttttccaggc agtttttgga
     3181 gtagaggtga tatgtccata ggtctttgat tcacgatgga tatcaatcgg tccaaatgac
     3241 cctactccaa tgctttctaa ttgttcttta tagtgattaa agaaatcaat taccaaactc
     3301 attgtttcat tcggtgtagt tgtaggaaaa ctcactcttt ctaaaacctt taaatcatca
     3361 ttgccaatgg cacaaacaaa tttagtccca cctgcttcta ttgagccata catttcttac
     3421 tccaccgtcc ttttatctag gaattcgttc ttccctgtct aatagttttt cgaaaaactc
     3481 atgtggttcc ttttggtacc aataggcaac agaagaaata tcgtcttgac gctcataaag
     3541 cttgatgtca tcatttccta gggtttggaa agtaacacgt aaattttctt tgaaactaat
     3601 ggggtcgggt aaatgccagc ggtacaaccc atgcatcggt aaagcatcat cgccaaaacc
     3661 atgaactgga tttggattag gttttccagc actaaaataa tcccgggtgt gatctctttt
     3721 agattgaaaa ggatagccca taaatagcgt attaaaattt tgagcatatg ccctttctcc
     3781 aaagttcttt ttatggaaag cccaagcgcc gccaaaataa tcttctgctc ctgtagatgt
     3841 tattgtaggg aaatcttcat ctccatctat ataaaactta aattctcctt ccccccacca
     3901 gtatctttcc aatgcgcaca aagcaaagta ggttcctaca taatacccag tgcctttgat
     3961 tccatcaata agggtgtaat cttttccttt tgtcgtgatg ggttcacggt tccatttagc
     4021 atgaaaatac atcgcatcat ccggtacttc agtcaatgca taattaaatg tataaaaaat
     4081 gtgcttaata aactcaggat gttcattcgt taaagtaatc ttagcttttt ttcgaaatgg
     4141 catctcaaaa tagcaattca tccctgatgt tggattcact acgattggta aggaattcac
     4201 ttcgcatctt gtcccaaacc cattacaaaa aaaatctcct aatggacttt ctacagaagg
     4261 agtggattca tcatcccaat aaatacgcaa aattaaatca cgtaagacga aactcccagc
     4321 gattgttttg tctgtcactg tcatccaaaa atgacgtaaa attccagggc cttccatttc
     4381 tgctaaagta attgtctctc cagcatttat cggaacagaa ggtgaccctt ttctcccaat
     4441 tcctagatga ctcgctgtca ttgccgcttt ccctttttca ccatttttat tttctggtga
     4501 aatagttcta ctttcctctc ccttgtggag ccatatatta tttaaacaat tcattttatt
     4561 cgtcctctat cctttcttca cttttttgat tattcatata gatgatttgt tgttgtgcct
     4621 ccgcaataat tgctccaata tctaaattat catttcctaa ctgcaaagcg attgacattg
     4681 ccaagggaag attcattcct gcaattacgt gcactctgtc agaaatatag gtaaaaaact
     4741 tttgatttac acttcctcca gccatgtcag ttaaaacaat tatttcgtct gtagtatcca
     4801 ctaactcttt aatttgttca tctatatcat caatttcttc gacatatgca cataagctac
     4861 taatttgatt atgcatacct gttaaaaact ctagtgtctc tttaaaaccc tcagctagta
     4921 ttgaatggct agcaatgatc aatcttctca taattcaaat ccttttcctt tacgctaata
     4981 ttccaaatgc agccataacc atcgcaaaaa caataacgag tagaatcaaa atggtcatac
     5041 tgattttttt cttactgagt agataatatg ctgcagcagt aataattact ggaattaatg
     5101 ttggtaaaat tttgtccaac attggttgga ttttcatact aacttcacca aaagtgaatt
     5161 taagtggcgt tgaaacactg ataactgaag caattaatga tccaactact gttagcccca
     5221 atactgaagc agcttcagtt aaataattaa tcttttcacc gtattcagta acaatcttca
     5281 ttccctgctt ataaccaaat tcaaagcctc tcattcggaa aaagaagatt accatgatta
     5341 aaatgaacca taaaaagatt cctacaggat tattttctaa agccatataa gccgcaattg
     5401 atcccatgat ggttgggatc atcgtcatca aaagagagtc cccaatacca gcaattggac
     5461 ccatcgtacc aactttaaag tcattaatcg catcttttgc ttctaatcct tgcttttcct
     5521 ccattgcaac acaagcacct aaaataatgg ctgccagcca aggctgtgta ttgtaatact
     5581 gaaagtgatt atttaaagct tcgatgtatt catcatcatc tttgtataat tttcttaaaa
     5641 taggtgacaa tgcgtaagtc acagatgcac cttgctgtgt ttgataatta aaggtacaaa
     5701 ctgacatcaa ccaacgatag ttcgctttcc taagatcctt tttcgttact tgatattttt
     5761 cgctcatttt attcatcctc cccaataaac ccaacatcag aagctcccgc agaagcagtg
     5821 atttgtgcat ctttttcagc tctatgatac acattaaatg ctaaagcgaa tcctatgatc
     5881 gccgctccaa taataggtac cttcaaaaaa gcggctaaga aaaatccaac aagtaaataa
     5941 ctaatgtatc gacctgtagg cataaagcgt aacaacatcg caataccaac agcaggcaac
     6001 atttttccgg ctaatgttag cccatccata aaccaattag gtaaaacatc caaaacgtaa
     6061 ttaacagcag actgtcctaa agtaacggca ataaatactg gaattgctgc agataaacca
     6121 aagaaaattg gccccaacca caaaacacta ttcattttct taaattctcg tttattcgca
     6181 tattcctgtg atttgcgaac aacaaaacca tttaagattt tgacaattac atctagttgc
     6241 acccctaaca tacctacagg tagtcctatt gctaatccgg cttctactcc aagctggcta
     6301 ccaaatgccg ttgcaataat tgcgcacgtt ccatagtccg gtacagatga gccaccaaaa
     6361 ccggcaactc ctaatgacat caattgaact gtaccgccaa ctatcaaacc tgtttttata
     6421 tcacccatca aaattcctgt gaataatccc caaaaaactg cgtaatttac aaagatcatc
     6481 ggaatcccat aataatcaac atgtttaata aatgctaata tagtcagcat aataatttga
     6541 aaaatagtaa aatgcattat ccttactcct ttatcctaat tttgattgaa tttcctgtgc
     6601 cttatccgcc ggaacaaatt gtgtaacaat ttctacacca gaatccaaca attttttata
     6661 cgtgctgata ttttcatctg atgcataggc tctagaagat agctgtaatg cattatcttt
     6721 aacaacagta ccgccaacaa ttagtcggtc aattctaata ccgttatcta ctaaatgaag
     6781 gattgtttcc ggctctttca cgatgacaaa tactttttcc tgatcgtatt tccccttttt
     6841 aaaattcgca atcgctgttt cttcagtgat aattgataca gccattccag caggtctagc
     6901 taaacgcata cttgattttt ggatgtcgtt atttgcgaca gaatcatcga tcaccatcac
     6961 tctgtttgct ttagacattg gtgcccattg cgtgacaata atcccatgca ataaacggtt
     7021 atcaactctc gacataacaa tactcataaa tacttcctcc tttatctttc attttcttac
     7081 aagcaattac catgccaaaa caaaaagaac ttgataaatc aagctctttt tacataatca
     7141 taaacgtatt taacctcatg aatcgggatg tcgacactat aataatgttc aacgacactg
     7201 aaagattgct taaaatgtgt ctgaaatttt tgaaattcct cactcgtttc attgaaataa
     7261 atttcatctt ccaaagtatt ttgttttact aatcgttcaa ttaagcaact aatgtgaaca
     7321 tataatccga aacacgtatt attatcaaat gaaattccta gatcattttg taagatgtat
     7381 atagcatctg aaacccgttc taataattta gtcggattta atatggtcaa ttgctccatt
     7441 aaattcgtta gactaaaatt cttcagaata ttattgttca aaactttcag ttcattatca
     7501 ttaaagtgtc tattcaattg attggagaat ttacttatat tcattcctaa aatcatatct
     7561 tcaattgaaa agaattctac atcttctaga tgtggattta gtgttccaac aataaaaaga
     7621 atattgttct ctttacgaag ctccgataaa tagttttcat tcactaaaga gtaatagtca
     7681 cacgtttcta tgacaagatc agtatccctt ggaaagctat cttcaagtat cctttttaat
     7741 ttaaacgaag ttcctaatcc gcttgcacaa gaacagacaa tcatatcctt cttaatattt
     7801 gatgattcat aaatataatc cacattttga ttttctttta cttgttcaag aatctgttta
     7861 agcggtaaat ctaataatat ctgatttgca acatcaatag ccattcttgt tgaaacattg
     7921 tttagtagtc cgaatttttt ttgagcgtct agttccaaat ttagataaat tttctccagt
     7981 gaacccatat caacaagtaa aataatttct tcatatccgg tacactcttg taagtatcta
     8041 ttaattttgt ctgcaatctc actacttgaa gtcattagtg gcatatcaat ggcgtcgtat
     8101 atatatctct caacgatcct attagcagta cttgctatac aggttgccgt tagatctcca
     8161 tgagccaaaa tcagtgctaa acgtttttgc tgaaattctt tactacacat taacttaaat
     8221 aaaataacca aaacattttt ttgaattttt gttaaataaa tatcccctat ttgaataaaa
     8281 cgattgacta attgaacttc tcgactacac caactattaa tatcattgat gaaggaatat
     8341 aatttatcgt ccgatgttaa ttggatttga taaatccaag aattcaaaaa gatagacgtt
     8401 atttgaagat aataatagtc aaattctatt tgaaaatctc tctctatttc cttaacatac
     8461 tgtctaaatc gaatctcttg ataggtggga tatgttaaag ctgaattatt ttggatatca
     8521 acattctttt gtctaaaata tctatcatat ttctcaaaaa gctgctgctt atcagtgtct
     8581 ttcttccacg tttgataaag atactctata agttcgttga tattaaaaac ttcgtctact
     8641 ttttccaaat catccatttg aatatatttt aattcattct gtcttttcat aaccttcatg
     8701 ccgttgaaat tcacccattg tggtaaatga tacatctgaa tataaagttc ttccaaatca
     8761 tctaagaaat aaaaggcatt ggcacaggtc aattgaatga tatttttcaa attgccaaca
     8821 ttttcactaa agcgatagtt taataaaaaa tctaataatt gttgagatat cagtattttc
     8881 tttgctagtc tttcttcttc tgatttaaaa aatatcttga ttaactgttt tctttcataa
     8941 agagaacgac tgtctaatgt tggaagtgtt agctttacag gtattcttct caacaaagtt
     9001 gataatagtt tatcctcagg tggttctgat gttgcaaata taatccagca acttgatgtg
     9061 taccagtttt cattatcacc catccgatga aatttcctcg tatccataaa ctgaaaaagt
     9121 ttctcctgac attcattgct caatgcatga atttcatcta aaaataagac tccattatta
     9181 gctaattctg ctaaaccctt tcttccatct tcggctcctg tatatgcacc ttttacatgc
     9241 ccaaaaaaat tggacaagaa aagttctgga ttattggcat attcactaca attaactgaa
     9301 atgaaagatg ccttctcttc tatataatta ttggccaaca aatccttata cacataattt
     9361 gctaaatagc tttttccagt tccagtctcg ccatgaagta aaatgggtaa gccatttggc
     9421 ggatagtaga ttgctgcttt aatttgagca attacatttc gcagacttcc ttgacttccg
     9481 ataacccttt ctattccaac cctaaaagag ctatcatacc atttttccgc ttcctctgaa
     9541 gagctaaaaa tttgttgatt tggaactttc tccggtaaag aaaagaagat tactggacga
     9601 gtattgattt ttccaaattc tccatctttt acgaattcat tcaaatattg agagacaata
     9661 ttacgactaa catttaattt ttcagatatt ttctgtgctg tattgttccc ccatttattt
     9721 ttaatctcag agttctctat gacataattg acaatgcgtt cttttaattc ttccatcaca
     9781 gcacctcctc gacactattc gaattttgcc gacagtattt ttccataaat atgacttgct
     9841 aaaaaggctt tgtttagatc attcaattgg aacgttgctt gttttgcttg atccgctaag
     9901 acgttgaaaa gatactctgg cgaaatcgca taccccaaaa tatcaacgat tgttgcaatc
     9961 agatcttctt ttgattcttc atctgaaagt aattcacgat acaacatcgt ttgtttgctt
    10021 actgtgtcat attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaaacgg
    10081 tcggataaat atttatagaa aatcagcccc aataaataat ttttatattc tgacgcatcc
    10141 attttactac ggagattatc tgccgcacta aataacttct gatttaattc tgcacccaaa
    10201 aagatacact cctatctctt atttaaagtt gctatatacc ctcttatttt agcatactca
    10261 gttttagaaa aagcaaaaaa ataaagaaac ttattcttga taacaagcta cgtgacgtat
    10321 atccctaaca caaaaatagc catatccttt ggtttggata cggctatttg atattactca
    10381 ttcaattatc aaatcacagt aggtgtgaat ctcatcggga tcggcaatat ctacttctga
    10441 ttaggatcaa aggtgatttt ctcaataaag gtgtgataca aagctttaac ttgcttcttc
    10501 tcactctgga taagaaagca atccaaacta gtcaatatct gttggacatc tttgacttga
    10561 atcggttccc cttgttgttg aaagatccct aagatttcat tctctcgaat ttgtaactgt
    10621 cttcgttttt cagtcaattc atttaaacga tcttttaaca tcggaaacaa ttcgggacta
    10681 tcttccaaag cagcttcctg tttttgctct aatagttaga ttttgcgtac cattttcttc
    10741 ttttattttc cttcgattgc tgattttaat atagtctaaa ggaaatttat atttattgta
    10801 ttctttataa cttcaagaga acttcgtttg agtattactg tattttttta attccataag
    10861 aaaattagtt attacctgcc acctaatcag caaatctgaa cctgagtcaa tataattaat
    10921 attattttcc atctccaaca ttgtaagtac tgttggtgtt aatataggga ctttgtacaa
    10981 ttgtattttt ttgattttat catctgcaca aaggagattt tttaaatcta atccttcttt
    11041 tatttcaaaa gttgaatttt ttaaatctat aagagtaaaa ccaattcctt catactgaat
    11101 ttctgaaaat cgaatttttc tcccagttga tagatcaagg ggcagaaaac cttttattac
    11161 attgtgagtg tcaccatcat ttacaatgtc attaggaatt ttgattttag aattctgtgg
    11221 agcacctatt ggaagataat aattcattat aattttgtag tcttcatgag gaaataaagt
    11281 acttttagga ttgctaagat attctcgtac cgaatctaag aatggcttat ccattgaatc
    11341 ttcatcccca tttaaactaa aaaacattcc tacaattgct tttgcaactc taagtgaatt
    11401 cattttcttt attgaatgtg ttaaatcaga cttaccattc tttaaacttg tattgttata
    11461 aaggaaattt ttattgtctt ctgcaaatct aatatattcc tcaacatact cactaccaaa
    11521 aaaactatta catttactac ataacgtatt ggaatggcaa cagttttttt gacaaatttt
    11581 ataaggtgca gaacttcttt ccgtatgcta ttccgattgt ccttgacaat gagcctcctc
    11641 ggatgtgacg atcttcggca ggagctaaca gttaaagtta gactgcctcg ctagcgttag
    11701 cacatccgag ctcattatca aggattcgct gcgccaat
//
LOCUS       DACCVH010000087        11615 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.087, whole genome shotgun sequence.
ACCESSION   DACCVH010000087 DACCVH010000000
VERSION     DACCVH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.087"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            6..305
                     /locus_tag="IVV98_002394"
     CDS             6..305
                     /locus_tag="IVV98_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7807992.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IVV98_002395"
     CDS             378..1739
                     /locus_tag="IVV98_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP7807993.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IVV98_002396"
     CDS             1761..2021
                     /locus_tag="IVV98_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7807994.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IVV98_002397"
     CDS             2035..2787
                     /locus_tag="IVV98_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP7807995.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IVV98_002398"
     CDS             complement(2881..3486)
                     /locus_tag="IVV98_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7807996.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IVV98_002399"
     CDS             complement(3539..4513)
                     /locus_tag="IVV98_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP7807997.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IVV98_002400"
     CDS             complement(4891..5670)
                     /locus_tag="IVV98_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7807998.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVV98_002401"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVV98_002401"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP7807999.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IVV98_002402"
     CDS             7161..8558
                     /locus_tag="IVV98_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7808000.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IVV98_002403"
     CDS             8639..9079
                     /locus_tag="IVV98_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7808001.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IVV98_002404"
     CDS             9227..9553
                     /locus_tag="IVV98_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7808002.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IVV98_002405"
     CDS             9554..10303
                     /locus_tag="IVV98_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808003.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IVV98_002406"
     CDS             complement(10383..10838)
                     /locus_tag="IVV98_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP7808004.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IVV98_002407"
     CDS             complement(11265..11540)
                     /locus_tag="IVV98_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808005.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT         3667 a         2015 c         2361 g         3572 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactg
//
LOCUS       DACCVH010000088        11542 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.088, whole genome shotgun sequence.
ACCESSION   DACCVH010000088 DACCVH010000000
VERSION     DACCVH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.088"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            346..552
                     /locus_tag="IVV98_002408"
     CDS             346..552
                     /locus_tag="IVV98_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAP7808006.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(754..1755)
                     /locus_tag="IVV98_002409"
     CDS             complement(754..1755)
                     /locus_tag="IVV98_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7808007.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1760..3673)
                     /locus_tag="IVV98_002410"
     CDS             complement(1760..3673)
                     /locus_tag="IVV98_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP7808008.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3841..4347)
                     /locus_tag="IVV98_002411"
     CDS             complement(3841..4347)
                     /locus_tag="IVV98_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7808009.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4507..4947
                     /locus_tag="IVV98_002412"
     CDS             4507..4947
                     /locus_tag="IVV98_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP7808010.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4973..6130)
                     /locus_tag="IVV98_002413"
     CDS             complement(4973..6130)
                     /locus_tag="IVV98_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808011.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6133..6489)
                     /locus_tag="IVV98_002414"
     CDS             complement(6133..6489)
                     /locus_tag="IVV98_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808012.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6787..7761)
                     /gene="sgrA"
                     /locus_tag="IVV98_002415"
     CDS             complement(6787..7761)
                     /gene="sgrA"
                     /locus_tag="IVV98_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAP7808013.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7957..8796)
                     /locus_tag="IVV98_002416"
     CDS             complement(7957..8796)
                     /locus_tag="IVV98_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7808014.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8981..9868
                     /locus_tag="IVV98_002417"
     CDS             8981..9868
                     /locus_tag="IVV98_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP7808015.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10462..11156)
                     /locus_tag="IVV98_002418"
                     /pseudo
     CDS             complement(10462..11156)
                     /locus_tag="IVV98_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(11140..11538)
                     /locus_tag="IVV98_002419"
     CDS             complement(11140..11538)
                     /locus_tag="IVV98_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP7808016.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3438 a         2300 c         1730 g         4074 t
ORIGIN      
        1 actggctttt ggcctcattt taggttatca tttgtaattt tatttcacag ttgatatgat
       61 tgttatgtaa aataaaaaag tttaggatac atcgaatttt tggggaaatt cttttggggg
      121 tatcctaaat cttttctatt atattcccat attttctatt attggtctag acgtatgatg
      181 gtaaactttg tacctatctg attgctgaat cattaattgc ttatcattag ccatctttgt
      241 ttcaagttcg ctagatgatc attttattca catcctaaca aacttgtcac atttatagat
      301 tcttaatcta tttatcatac aattataaaa aaggaggtgc tgcttatgaa agctatccat
      361 atttctttgc tttttttcgc tagtgcattg attttatttg ctattcatct ttgttcccag
      421 ccttatatca ataacaacgg aatattagtg gaaccagcat tcttttgctt accactcggc
      481 tttttgtccc ttcttgcctc cgcaggcttc ggatttgttg ctttttttaa acgatcaaaa
      541 caacaaatct gacttataaa atttacgtaa aagagatcgt gacaataatc gtgtgatatt
      601 cccaaatttc gaataaaagg tgccccttgc catctctaac tcctcagtca caagttacaa
      661 tattcataaa ccatgaaaag cttgtttatt gaaattgctc cttgtgactt ggagctaagt
      721 gacagattac aacctctttt gcatcataag actttactcc ttgaaaaaca ttactaactt
      781 ttgatatgtt tcttgcgctt gtttattgct gaaatcaaac tgatattcat ggttcaaaac
      841 agcatttttc tccgcataat ctacttttgt gactttcacc cccgctttct caaatacaga
      901 agttacttct tccatttgtt tcgtaaacgt atttgtattt ccatccgtta agaatgtgtt
      961 ttgcgtccaa cgatccgcat gtctgaccaa ggctaaactt ttgaccttct ctgattgttc
     1021 aaagtcctta ttatcaaagt aagcccatcc acatttttca taaagaaagc tagagatttt
     1081 atcacttact tgagtaagtg cagaaggatc caacagacca gacaaagaaa taaacttcgt
     1141 aatctgcttg ttctccaaag tcggatcaag atgatcagct tttttaattt cttcattttg
     1201 aagtgctaac aaatattctc cactaatttg tgcacctgcc gaatttccac caatcgaaat
     1261 attcgaccaa tctgcttgat cttttatctc ttttttagct gcttgaatgg cttcgttcaa
     1321 ttggataact ggtgtaggat gttttgcttc cggtgatcgt tcataatcta tatttacgat
     1381 gatttgctgc gtgtctgaac atagatattc caaataatca cgacaatcat ttttatcccc
     1441 tcctacatat gcgcctccat gcatccagaa aagaatcggt aattttttct tttccacttt
     1501 cggtgtgtag atatccatat tattattttt gtactttgaa ggataggata tttctttttt
     1561 tatatcgatt tgttcgattt tttgctggaa atcatctggt cgggcatata cttgttcttt
     1621 ttcacttgtg tcaaattgtt ttctaacaag caagctaatc ggctttggtg tgatttgatt
     1681 aatcaaaaat acagtgacta aaataactac gatgataact ggtactgcaa tcactattcg
     1741 cttgaaccat ttcattcatt taccctctct ttcttcgcca aatccatgtg ataatcgtgc
     1801 taacagataa aaatccacct gaataaatga gaagcgaatg tttcttttct ccagttttcg
     1861 gcaacattct tttttttgca tctgtctttt tttgtacttt cactgtcatc tgaatcggtt
     1921 gcgtatcatc acttgattga tcctctcgag gttcattctt tcccttattg tctgcattct
     1981 ctgtcggatc ttgctttttt ggtggagcta ctgggatttt tttgtaatag aaaataatag
     2041 ttggtatcgt ctcattaaaa atcccttcag tcggtccttc aacatttgct aattcgtatc
     2101 cttcgaatgt cttttgctct gtcatataat tttctccata agctccgtaa agctggattt
     2161 cgtcctggtc tttgagtaga cttttattgt tttcatccac atactttacg tttatctgat
     2221 catggaacac tactttcaaa aagtccgtta catgtttcgt gtaggcagca tggtcaactt
     2281 cctgtgcctt tccatgccct gctccttcta ctaataaaag atctttatac cctcctgata
     2341 actcatataa tttttgcgcg ttagacacag gtactacatc atctgctgtt ccatggataa
     2401 tcaatttagg caatgaatct gacattccaa tcgtaggtag agcagctttt gtatccaaat
     2461 gcatctcctg atcaaaatag tattgtttca aaaggcccat aaataaatct tcatgctctt
     2521 gatccccaat gatgtctaac tgatttttta tggcatccgg tagtgcgggg gctactgtct
     2581 ggctgtacgt aaaacgtagt tgttcatcaa ttgatgcaaa tccgcaattt tcaataattc
     2641 ctttgacatt gacaggaata tctttcgcta atacagacat catcgtagct gctcccatcg
     2701 aaccaccata aagtaaaatc ttttgagatg gccgctctcg aacttcttga tttatccagt
     2761 aaaggacgtc atctgactca tattgtccat aggtcacata atcgcctccg ctattaccag
     2821 tcgctctgga atcaacaaat aataaattat acccggcctt ataaaaatca ttgtattctt
     2881 ctgtaacgat cccgttattc caattccctc gaaatccgcc atggatcatg actgttttat
     2941 ctgaaccttg atcgacataa tatgcatata catccatcat tttgccatct tgtttgttta
     3001 gtacagtttg atgaagttgt tttgtatttg gatagaagcc tgtgttttct gtaggcgttg
     3061 tcccatcatc tgtacctcca agcatcgaca tcaacacact gttttttgca aaagcgatat
     3121 cgtacaatag ataagtagca atcagatgtt tgataatctc tttatctaca ccataatcat
     3181 taacagcaag ctcagtgact aataactcta ttaattttga cttgatgtct tctgttggtc
     3241 cattaagtat ttctgtcatc tgtttaccga agtaattcaa atattcttta ccattgaaat
     3301 tttcaccttt accgatatca tcattttctg tcccattctc tttgtcactt actttagcag
     3361 aagaggattc gtcgtttgac atttttgtag ctgttgcttc ttctgtttgt tggttatctg
     3421 tggtagcggt cgtttcttga tctgtgctag taacagatgt ctcaaccgtt gtttcagtat
     3481 ttgtttctgt ttgtgaagta ctcgatttcg tttcatttcc agcatcagta gtttctgtgg
     3541 tttctacctc ccgagattcc gattcggaag aaatgctctc tccatatact gtccattgcg
     3601 ggacgcttgt acttacagca aataagatga ccaacgctcc ctttaatact tgttttgttc
     3661 tcaagctatt cactcctttt tatgtttcta ggagaattat atgtaaacgc aaacattttt
     3721 tatacaaaaa ataaatggtt tatcccataa aaatagaaca ggattatttt ctcattttac
     3781 gtaataaagc agaatggata aaccagtatc cattctgctt tttttaaacg aagaaacaac
     3841 ttattgctcc aaaaatgtca gaaatcgttt atcccaaatt ttctcgtaaa aagcgattgt
     3901 ttcctttgct ttcataaaag gattatcata agttgtcgtt gctcctctac acatcataag
     3961 ctggtatcct aatccatgag caaacttcac agtcgtatct atacaatact ctgcttgtgc
     4021 cccacataat tcgatcgaat gacagtccaa ttcagttaat aaaacactca aattagtctt
     4081 ataaaatgaa ttcgcatggg tttttctcac aaaataactg tgctcaggaa tagataattc
     4141 cgacaatagc tcccatggtt ttgtttgtgg cactaattga gcatcttcgt gttgaacgaa
     4201 aataactggt ttcccaatcg tttcgtatgt tttgattctt ttattcacta atgctgtcac
     4261 tgtttctaat tcgtgtatcg gcgaagaatc aaaacatacc cctttttgta aatcgatcac
     4321 tactattgcg tcggctgtgt ttgacatact tgtgccttct ttcttttttc ttgatttaat
     4381 agtatttctt atctagctag ttccattata cgtgacaaca ttttcttatt ttacacctct
     4441 aaatggcact tttcgactat ttcttcatgt tattatttca taaatactta gctattggag
     4501 gaatgtatga tgattaaatt gtatacaggt tctggctgct cgtcttcaag acgcgcaaaa
     4561 cgttggctta tcgtccatga tataccgttt atcgaacaga acttaattcg tcaaccacta
     4621 accaaaaatg aatttatcca cttactaaaa ttgacaaaca acggcgtgac cgaaatgctc
     4681 tctactcatt ctattagtta taaaaatctt gttcacagaa tagatgaact cagtttgagt
     4741 gaactatata ttgagattcg tacatcccct tctttattga aaaaaccgat tatctacgac
     4801 caatctgcaa aacttttgac tggatttagc gaagataaaa tcaggatgtt cctttctaaa
     4861 actaaaagaa agcaagagct caacgaactc ttgctttctg gtcatcttgt cgattttaaa
     4921 gaaaataatc tttttgcaat gtcttaattt tggcataaac aatctgcttt tcttaattaa
     4981 cgaaatccaa tttttccaat atggatctat ttttctcatt cctgattttt atgatttcag
     5041 ctttcagacg cgcccaatca ttttttgtag gttgtccatt ccagtaaaat atctgtgtat
     5101 tcgtttgatc atatgccttt ttgtcgatag gataatcgct aatgacaata tcaggtaact
     5161 gatcagcgga tgcactatat tttattgggc gttcagtcat agataatatc cttttctttg
     5221 cccataattc ctgtgtttta ccatactttg attgaatata gaatatgaca ggttgttcgt
     5281 gttttataaa aatatccctg actaacatac agtattgaaa aatcaaccgt ctgttctttt
     5341 cataataagt attaagctct ggaattctgc gagctacccc actaaaaaac tgttgcatga
     5401 ttggatacat cactggaaat atatgctgaa aatctctgtc ttctgctgat tttccaaaag
     5461 catccacctt cttttttgtc ccaaaaaccc ttgaatacaa atggatcatt gccaaattga
     5521 catatagata atttttttct gaagttgtaa aacaaatctt gaagtttttt tcaaaatttt
     5581 ctacaataga cgattcaatc cagccccaac tttcttgtac tttatctgga gtatccaaca
     5641 aatcttcttc caaataggtg ttcattacac caaacataaa ataaaggtaa gcttgctctg
     5701 ttggagtgat gtgattcatc gaccagaagt ttgcttcaaa aaaaggctct agtatgtaat
     5761 gcgtaaactc ttcttttgtt atcaatggat gcacaaattt gttcatctct tctgggacat
     5821 acgtaatcga gtggccttgt ttcattcgtt gcaacgaaat tcttagtagg ctgatccatt
     5881 tctttctatc tatactacgc gtatatggcg catgtttcgc aaatttttct aatagttgac
     5941 gtttattttt tatacttgat aatatatcag aatgattttc gtcgaatgac tgccaataca
     6001 tcaagtgaaa aaagtatcgg atacggtatt cttctccttc tatcggatta ccttttttca
     6061 agctgcaaga taaatgatag tttttcaaaa tagtattaag ttctcttaat tttctttgaa
     6121 tcgtacgcaa acttatataa ttttttgact aagattttct aaggattgat aagtaccttt
     6181 gtaaagtgaa tccagtaaaa tataaccaat cgttccctct aaaagtatag aataaacttt
     6241 actcagtaaa aactgagaag aaaactcgac ttttatcatc ttgttttctg aaagaaaaga
     6301 taatttatat tctggatacc tttcgcaaaa cgattctgct tgttgaatca ccgaattcat
     6361 cttagccagg gtgtagttta gatctaaagc gatatccttc accacatata atttctcgtc
     6421 tctttcataa caatagttca aaaattgata tacttgcctt tcattgatat caataaattc
     6481 ttcaaacaaa gtacatactc ctttttatct attatttaga cttattccga cagctacatg
     6541 aataacgtac aaatagattc gttactgatt tttcagagat actaccatgc gcagtgtgca
     6601 ttgtcaatta ttcttgctct tattttccat ttgtgttcct gttatttcct gtttctcaaa
     6661 tatgttagta aacaaaaata gatctggcaa agctacaact tcgccaggca atacagcact
     6721 ctcgaatgaa atattcactc aaaaatctat cgttttattc aattttagat ctgttgcttt
     6781 tattctttat ttcactcgat ggaagagaga acgaaaatag cttgctccta caatcaaaat
     6841 gagtaacaca cccatccatg taattagctt gttcaaggtt ctactaccag tttctggtaa
     6901 atcgcttttt ctattatctg tttctttcgc tttttcttga tgatcaattc cacgagaaac
     6961 aaaatcaggc tgttttagca cactttttag gttgctccct gcatttctct tttgttcctt
     7021 agttggtatg ataggtacca aatcaagttc attatttact tttcctgtgc tgctttcgct
     7081 gctcgtgctt cctgtgctac tctcactact catgcttcct gtgctacttt cactactcgt
     7141 actctccgta ctgctttcgc tgctcgtgct tcctgtgcta ctttcactac tcgtactctc
     7201 cgtactgctt tcgctgctcg tgttttctgt gctaatttca ctgctcgtac tctctgtact
     7261 gctttcaccg ctcgtgtttt ctgtactgct ttcactactt gtgctatccg tactgcttgg
     7321 cggtccaaca actgtccaac tgcttggttt caaattctcc gtgatcgtca tctgtccatc
     7381 ataaaaaaca atcaaatcaa ctttatcttt actcttgatc tcatcaatcg atagttctgc
     7441 agaaatcatt attgtatact caataccagc ggtccattgt acgtctttta aataaacttc
     7501 cccaataact ttttctgaac ttccattacc atcccaacca tatgttagaa cagcatgtac
     7561 atcactagca ttcacgcttt tgtttggttt gactggaata gtaatgactt gttgtgtcat
     7621 gtcataaaca atccgatcag ttttcacagt aaatgaaaga ttctcatttg cccgttcatt
     7681 tgcagaagta ctgattccaa tcattgctgc aattatactc agcccaagaa taacaaataa
     7741 tacggtcgct gttttcttca tttctatcac tctccatata attaccttct atttgataaa
     7801 ggaattatat aaaatgaaaa tgatgagaac acgacagtca gttgtgaaaa tctaacaaaa
     7861 gatgtcgtgt attcgcttga atttgtttac tttttcgttt aatcaatgac agacttaaaa
     7921 aagcaagacc gatatcagcc ttgctttctt catcttttat tgataaacag cagtgtattt
     7981 cttcatccgc tttgttttat atgcatagag taacaaacca acaatcaaga ctaacaagaa
     8041 taatgtagtt gatatagatg cttcagcccc aaagtttccc ccagtaatta ttgtattttg
     8101 cgattggatc agagtggaga aaaaaccttg ttcttgcgtt ccgctgactg gtatacccaa
     8161 aatagctcct tgtgtccaat tccaagtaat atgagcacca atagccgtaa ataaacttcc
     8221 tgtactgtag ataagtgcgc tgaaaaagca acctgctaaa aagatattga aaactgccag
     8281 aaatgtcatg ttaggattca atccgtgcaa aagagcaaat aatgcagcag atccaatcat
     8341 tgctattaac ggaccaaatc taagcatctg atgctgaaaa aagccacgga ataaaagctc
     8401 ttctgatgcc cccactgcaa taaataaaat aaaactcgtt atcagcggca caatgtttgc
     8461 gtttcctgaa tctaaccgat acgcccccgt caaatataat ggactagtaa taagcagaaa
     8521 cactccaatt ccaacaacga gacctcccgc taaatacccc cagtcttttc ctcgaacaga
     8581 aacaccataa tcttctattc tttttccttc gaccttacta gcaagaaata aagctagtaa
     8641 aaaaacagct aaatgtccga ccgtaccggc aattgctcca atccattcac tatttccaat
     8701 aaacatatcc gcaagtgcat tattgacaag aattcctaaa acaaaaccaa caaagactat
     8761 taaaacagat ccaatcaacc gaataatcct gatcatcttt catccctcct ttatattaag
     8821 tttaacaacc cttttctttc ttgtctcgtg aaaactatgt aaatgttctc catcatagag
     8881 agaatagatt tttacgaact aagaatatct acagcaacct tacgaaaatg aaagactgtc
     8941 tccctaattc ttctgttaga ctgtttttaa taaggaaagg atgggaaatt ttttgaaaaa
     9001 acaactacta attatgtgcc tttcagcatg tgcaatttta ctattctcag gttgtagcaa
     9061 gtccaatgaa acgattgcaa cgtttaaagg tggaacactt acagttcagg atttttatga
     9121 taacccaaaa gttaaatcaa ataatcaaac actattaaaa aaaatgattg tcttcaaagc
     9181 atttgatgat gtatacggaa aagagatttc ttcaaaggaa gtaacaaaag aatataatga
     9241 acaaatcaaa aaactcggtc caaactacaa ggaacaatta aaagcagttg gccaaacaga
     9301 agagacatat aagaaactct ttaaacagat gctggctttc caatacggtt tgaaagccaa
     9361 tgtaaaatta acagataaag atctagacac tgcttggaaa gaattctatc cagaagttag
     9421 tacacagatc attctatttt cgactaaaga agaagcagat aaagcaaaaa aagaagcaaa
     9481 tgaaggagaa aatttctcca agcttgttca agcttatgga aaaaataaaa cattaaagga
     9541 aactgatgga aaaatgaatt ttgattcaac caatccagag attcctactg aagtaaaaaa
     9601 agcagcattt aaactaaaaa acggggaagt ttctgatatc attcctgtaa cagatccaac
     9661 gacttatcag caaagctatt atctagtaaa aatggtaaaa aaacaggata aaggttctaa
     9721 taaagacaaa tacaaatctg agctagaaaa aattgctacc gaagcaaaaa ctcttgatac
     9781 ggaattcatg gataaaacaa tccgtaaagt gatgaaaaaa gacaatgtaa ctattaaaga
     9841 tccttatgta aaaaatatat tcaaataaac aaatttgacc caattgggga tgtggcaaaa
     9901 tttgagaagt gatttttgga aattccttct tatttttgag gcaaaccact tttgccacaa
     9961 cttcatcggg gccttttttt atttgtacca aaacaaatca ctggatttgt tacaatcatg
    10021 aggatataat ttaaaaaagt tttttatttc tatcacatga atcaatgcgc cattaagtag
    10081 attctttcat gcttccctat tttttcactt gccgtatcgc ttcaaaaaca actatcataa
    10141 actcaaactc gactgaaaag ttattttaaa aaagactaaa aatatccctt ctggacttgt
    10201 tcttcttatt ctgttatact agagaaacac gaaagatatt tttatgcgac acttttcatt
    10261 tgtttttatg aaatttattc aaaactggcg taacttcaga gttacaagga tgtattagag
    10321 gttagggaat acatcgttta aatgagaaat aagtaatagt tagtaatagt cacccaaact
    10381 ttaaattaat gaatattgaa tcgtcagata gcctcctcga gttttcgaga aggctatcgt
    10441 ttattttatg gagaaattga ttcagaagta atcagcgacc ttttttagtt caccaatcgt
    10501 ttctgcttgg aaagtttgca cccaatcttc ttggaagccc ctcactgctt tatcaatcga
    10561 gggcatctct aatacttgat ctagtagctc tttacctaac gttatcgctg agctccagat
    10621 cgaatggctg tagtgacttg ttcacaattt ttgaaactag ctgctaatat ttttgttggt
    10681 ctttgcgtac gttcgatctc agtccgcaac gaatcaatca ctttcatagc atcaatgcct
    10741 tgattttgca tcctgttata ataaggtgca atataatctg ctccattatt aatagctaaa
    10801 tacccttgta attctgtgta aatagctgta ccggtaatca aataaccttc ttttttcaac
    10861 tttttgatcg cttgaaggcc tgcttgattc accggcacct tgataaacgt atcttttccc
    10921 agttcttcta tgataactcg agcatcctct atcatttctt cttccgttct tcctattgtc
    10981 tgaatatgga taggaatctg tccgattatt tttttgattt ctttcatatg cgagaagaag
    11041 tttgacgctc cttctttttt cagaattgta ggatttgttg ttacgcctgt taaattcaaa
    11101 aactgttgac aagaataaat actttttgta tttgctgtat caagcatgat ttccatatag
    11161 ctttccccca ttctgatcct cttgatcgat tttaatgatt gtcccctttc ttaaatgcgg
    11221 catttcctta tcttctacat acattgttcc tggaagttcc ggctcatgag atccatcaaa
    11281 ttttatcgtg atatgtccta attcattcaa attagtttgg acaacatctc ctactgctgt
    11341 gattacatac atttgtttat caaaacagag cttcatatca caagttattt cttttcttac
    11401 ctgattcaat tcaatcttat aacaataatc tgttaatgtt tccggtgctt catctccaaa
    11461 taaaatcatt attttttctt tcctgaatac ttctgcttct ataccaacat ctgttacaac
    11521 cgtttcaaag atcgtcatct ct
//
LOCUS       DACCVH010000089        11319 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.089, whole genome shotgun sequence.
ACCESSION   DACCVH010000089 DACCVH010000000
VERSION     DACCVH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.089"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(68..730)
                     /locus_tag="IVV98_002420"
     CDS             complement(68..730)
                     /locus_tag="IVV98_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808017.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(743..2245)
                     /locus_tag="IVV98_002421"
     CDS             complement(743..2245)
                     /locus_tag="IVV98_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808018.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            2793..4472
                     /locus_tag="IVV98_002422"
     CDS             2793..4472
                     /locus_tag="IVV98_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP7808019.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            4599..5078
                     /locus_tag="IVV98_002423"
     CDS             4599..5078
                     /locus_tag="IVV98_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP7808020.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            5297..5977
                     /locus_tag="IVV98_002424"
     CDS             5297..5977
                     /locus_tag="IVV98_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP7808021.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            5985..7316
                     /locus_tag="IVV98_002425"
     CDS             5985..7316
                     /locus_tag="IVV98_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7808022.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            7331..8293
                     /locus_tag="IVV98_002426"
     CDS             7331..8293
                     /locus_tag="IVV98_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP7808023.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            8404..8742
                     /locus_tag="IVV98_002427"
     CDS             8404..8742
                     /locus_tag="IVV98_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP7808024.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            8821..9528
                     /locus_tag="IVV98_002428"
     CDS             8821..9528
                     /locus_tag="IVV98_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP7808025.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(9631..11112)
                     /locus_tag="IVV98_002429"
     CDS             complement(9631..11112)
                     /locus_tag="IVV98_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7808026.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3581 a         1962 c         2360 g         3416 t
ORIGIN      
        1 aaaaatccga accatatctg cgagacagat atggttcgga ttttttattt gatcattatc
       61 ctgtttttta aacttcgatt ttttgaaatt ttttattttt tagttcaaag acttcatcac
      121 agctttttgc tacttcaatc tcatgagtca cgatgataat acagcgattt tgttcatggg
      181 cgatttcttg gaaaagtttg acgatatctt gtgaagttgt ttcatctaga tttccagtag
      241 gctcatccgc tacgattagt tgatgttcac agcagatagc acgaacgata gcgactcgct
      301 gctgctgacc tcccgaaagt ttggtcacct gtttttttgc taatatttca tcaattccta
      361 cacgagccag tcgatctaaa gcaacttgtc gataattctc ttgcttggtc ttagtgattt
      421 ccattgctgc tatgacgttg tctagagccg ataaataagg aagcaagttg taagcttgga
      481 aaataatcga gacatcattt ttacgataac ttcttaaccc gattttgttc agtgaacgat
      541 cttgatagta tacctttcct tcttttggtg catctagtcc agaaataagc gaaagaaaag
      601 tcgtttttcc agaaccactt gctcctaaaa tagcgtacat ttttccagct tcgaaattca
      661 gttctacatc tttataaagc gcatcttgcg gatcttgata ccaaaatccc aattgttctg
      721 tccgtaacat caaattcctc ctttagttta ataggatttt tcttgggttt aatcttaata
      781 tccctataga agctaaaaag acagaaaaca gactgattcc aaatgctact ccggctaata
      841 gtcccaattg tgcaggtttg acattgattt ccaattcgct gacttgatca gaaacagcaa
      901 atggattatt cgtggttcct tgttgaccat cgcgttgacc gccttgttct tgtctgttac
      961 ctggcatttg tccaccgcca ggagcttgct ggttttgtgt cgtggtttct gtctgttggt
     1021 caagtagctg ctgtcccacg gcattcgcga cgacgtttcc gctaagcgaa gcaactccta
     1081 atgcaagaat catacaaata gccacttcgg taaacaattg gagaatgatt ttacttctgg
     1141 attctcctaa agatagcaag acgcctaact catgccgacg ctcccgaatg gtaatcataa
     1201 tgatcagagt aagtatgata ataccggcta cagccactag taaaacaaca tttttagaaa
     1261 aacttgccac gttgtttaaa ggttccaaca ttgactgata catggaatca tttgattgta
     1321 agctaaatgt atctgtgtcg atcagcttct cagcttcttt gagaaactca tccattttat
     1381 ctggatcaga tagagtgtaa atagcagaat ctatcgtgtt atcgtcagat gtcccattta
     1441 gttcatttgc aaaagtgtaa gaagtgtaaa gtgtattcga cggattcatg aagttgaatt
     1501 tcatacccat actgccgctt gtttcgctgg attcataaat tcctttgatc gtcatttcat
     1561 aagtggtatc ttcatcttca gtactcgtga ttgtgaaagt atctccgact gccaggtcat
     1621 ttgtttctgc tagagtagaa tcaatgacta cattgtttgt gcctttgtcg ctgtcatcta
     1681 ttccttcacc atccgtgatt tttgctgttc catcagaaaa attactattt tgtgcagttg
     1741 ctgacacacc actgatttga aagtctgctt gagtcatttg cggattcccg cccattcctc
     1801 cagcaggttc accgcctgca tcagtagttt ctgaactgtc ttcacttgaa tcagaactag
     1861 tgatggcagt tattccatct tttgccatag ctgaggcgga actttcaaag gaataactct
     1921 ttacattatc taattcagct attttttccg cgtccgttaa ggaaactggt gtaagagaaa
     1981 aactgcctgg atctggacgt tcttcagtgg tagaaccgct tgaagaagtt tgttcctgtt
     2041 ttttaaatga agcttctcga ttggcactta aagtcactgt tgctccaact tctttttgtg
     2101 cttgattcgc tgcttcttct gcagcgcttc gaatcgtgag gccagctagc acaaaaataa
     2161 gaatggctgt gaacacggca aacaataaca atgaacgtcc ccattttact tttgtacttt
     2221 tccatgcacg tttcataaaa ttcatatttt gcatccctcc tagtagatgc atttgataat
     2281 agacaaccta tcttaaagct agcttaaatc ttatgctgtt tgcacaccat caacatgagg
     2341 ttctgtatat ataaaaagtc actatagtta ttgcaaaaaa tgtggtaaaa tgaaaaaagt
     2401 atgtttcaaa ccgacgaaga agaaatgaaa gaggaatagc aaaagaaatc ctagatgcta
     2461 cagagggatt tttacgtgca tagttgttct aacaattgct gatactagcg atttagttta
     2521 tttgttgtat aataatgggg aacagctgaa tacttatata agtattctgg ctatagcgtt
     2581 tcgcaaaaga tccattttgt taatgaagta tatccaaaat aaaatgccca tccaactgtc
     2641 agaacgcgga tgtgctggta attttcctgc tgattctcca taagttgaga aatagtgatt
     2701 ttgcatatgc ttcattggaa tggctcatat atttagataa agaagaaaat cgacatcttt
     2761 aaacttggat gtcataagaa gaggtgaagt ttgtgagtac cattaaaatt atcccattag
     2821 gcggcgttcg tgaaaatgga aaaaacatgt atgtcgcaga agtgggcgag gatattttta
     2881 ttttagattg tgggctaaaa tatcctgaaa atgagttgtt ggggatcgac gtcgtaatcc
     2941 ctgattttac gtatttagaa gaaaacattg atcgtgtagc tggtgtcttt ttaacacatg
     3001 gacatgcaga tgcgatcggg gcacttcctt acttgttgtc aaaaatttct gtaccagtat
     3061 tcgggacaga gttgacgatc gagttagcaa aattgaatgt cagtcgtaat gaagcagcca
     3121 aaggatttaa ggatttccat gtggtagatg agcatacaga aatagacttt ggtgaaacag
     3181 tagtgagctt tttccgtacc actcatacga taccagattc agtggggatc aatctgaaaa
     3241 caaaagaagg tagtatcgtt tatacgggag attttaaatt tgaccaaacg gctatcccaa
     3301 tgtatcaaac agattatgca cgattggcgg aaatcggcaa agaaggagtc ttagccttac
     3361 taagtgaatc ggcaaatgca gaaaatcctc agcctgtagc ttctgaagcc caaatagcag
     3421 atgaagtatt tgatacgatc aaatattggg aagggcgtat catcgtcgct tgtgtagcaa
     3481 gtaatttgca acgagtgcaa caagtattgg atgcagcaga aaaagcacaa cgaaaagttg
     3541 tcttgactgg tcaagatttc gaacgaatta ttcgcacagc gatgcgttta gaaaaacttc
     3601 aattaccaag tgaagatctg cttgttacgt tgaaagacat gaaaaactat gatccagaag
     3661 aactgatcat tttagaaact ggccgaatgg gtgaacccat caagtctctg caaaaaatgg
     3721 caaacggtac acaccgtaat gtcaagattg aagaaggaga tttggtttat atcactacta
     3781 cgccaagcat cgcgatggaa accatcgtgg cgaaaacgga agatatcatt tatcgagctg
     3841 gtggaacagt gaagttgatc tctgagaata tgcgcgtttc tggccatgcc aatcctaatg
     3901 acttgcaatt aatgatcaat ttgatgaaac caacatattt tgtgccagtt caaggagagt
     3961 atcgtgaatt agctgctcat gcagatttgg ctcatgcagt agggatgcca tacaaaaata
     4021 tctatattac tggacgcgga gacgtgctgg aatataagaa caagcgtatg agtgttgcag
     4081 gaactacaag tgcagaaaat gtaatgattg atggattagg cataggtgat atcggaaaca
     4141 ttgttttacg tgatcgaaaa atcttgtcag aagacgggat tttcgtagcg gttgtcacta
     4201 tcagtcggcg agaaaagaaa atcatttcaa aacctcaaat tacttcacgg ggattcgttt
     4261 acgtaaaagc tagccgtgat ctgatgaaag aaagcagcaa tatgattgaa acaatcgttg
     4321 agaaacattt agaaagcaat gattttgagt ggagcaaatt aaagcaagac atccgagatc
     4381 aattaggccg ttacttattt gaacaaacaa aacgccgccc agtgatcttg ccagtcatta
     4441 tggaagctac tcaacgtcga aataaaaaat aaacaaaaag agtaagatga acctctctat
     4501 agagtgctcg tcttgctctt tttttgcgaa aaacaaataa tttttgaata cagcatccct
     4561 cgctttataa taaacgatag aataaaggga gtgaatcaat gatgagtcaa acaaaagtcg
     4621 aacgttattt agaagaacaa aagatcagct atcaaccact tgattttagt catgtggtag
     4681 aagaatcttt cacagaagaa ctacaaaaaa gagggattga tccagctttg atatgtaaaa
     4741 ctctcgtagt gaaaggaaac aaaactgggg tgatcatcgc attgattcct ttgaacgatc
     4801 acttagatta caaaaaaacg agacaagtga cgaaagatcg taaagttggt tttcctggaa
     4861 tggattttgt attaatgcat acaggatatc cccacggagc aaacacccct attggaataa
     4921 aactcgcaca tcctgattat tgttttttag cagacagttc tttaaaagaa aaagaagaag
     4981 taattgtgtc aagcggtgaa atcgggagaa gccttcggat aaaagtagcc gatttagaaa
     5041 agatcgtcca tcctatttac gctgatttaa ttagttaagg gacgagaaga gaagctaagc
     5101 agagcagaga cctcaaactt gagattatat ctgcttggta cttggtgcat cctgtattat
     5161 ctgttacaat tgctttgtac atactgtact atcaatccaa tgaaaatata tttagcagct
     5221 atattttttc attgatgtgc aagtgatgaa atcgttttta ataaaaaaga tacagagaaa
     5281 acgcgaggtg taaaatatga aaattacgta tcatggacat tcctgtttaa caattgaaat
     5341 ggaaaatggc caacgcgtga tgattgaccc gtttattaca ggaaatccat tgacagactt
     5401 aactgcagaa gaagtaaaga cagattggtt gctgattact catggtcata gtgaccacat
     5461 aggagatatg attcctattg caaaagaaaa tcaagccaca attatcagta ttgttgagat
     5521 tgctgattat gcgaacagca gaggagtaga ttcattcggt atgaatatcg gtggaaaaca
     5581 tgcgtttcca ttcggcgtgg taaaattcgt acatgcacag catagttcaa gctatgaagt
     5641 agacggtatc gttcagtata tgggcgagcc tagcggaatt attattcaag cagaaggaaa
     5701 aacgatttat catgcagggg atactgctta tttcagtgat ctaggattgc ttgcagaaga
     5761 attcgatatt gatgtcgctt tcttgccgat tggcgataac tatacgatgg ggccagaaga
     5821 tgcagcaaag gctgcgcaaa caattcgtgc caagaaagta gttccaatcc attacaatac
     5881 tttccctgtc attgaacaag atcccgaatc ttttgtagag ttactggaag atagtgaagg
     5941 aaaaataatg agcgtctcgg aaacgctgga agtgtaggca gaaaatggcg acaaaacatg
     6001 atttgatttt agaatatatt gaaagtttac ctgttggcaa tcgaatttct gtaagaagca
     6061 tcgcaaaaga attgaatgtc agtgaaggaa cagcgtaccg tgcaatcaaa gatgcagaaa
     6121 atgtcggact agtttcaaca attcaacgag tagggaccat ccgtatcgaa cgcaaattaa
     6181 aaaaacatat tgaacgtttg acatttggcg aggtcgtcag gatcattgaa ggggacgttt
     6241 taggcggggc ggcaggatta gacaaggtct tgaataaatt cgtcatcggc gcgatgacta
     6301 aacatgccat ggaacgctat attacgccag gatcactaat gatcgtcggc aaccgggcgg
     6361 aagtccaaaa attagcattg gaagatggcg ccgcagtatt gatcacagga ggattcaata
     6421 cgactgctga gattgcaaag ctagctgatg atcttgaaat gccgatctta cgcacctctt
     6481 atgatacatt tacagtcgca accatgatca accgagcgtt aagcgaccaa ttgatcaaaa
     6541 aagatatcat gcttgtcagt gatatctata tgccagctga aaagactcat tatttgcagc
     6601 agacagatac gatttctgat tatcagcgtt tgtcagaaga aacgcagcat tcgcgttttc
     6661 cagtcgtcaa ccgccatcat cgtttgatgg ggattgttac ggcaaaagat gttttaggga
     6721 aatcgccaaa ccagatcatc gatcgggtga tgacgaaaga accaatcagt gtaaagaaaa
     6781 caatgagtat tgcctctgtt agccatcaaa tgatctggga tgggctagaa gtcatgccgg
     6841 tcgtttccga tgacttgaca ttggaaggct tgattacccg gcaagatgta atgaaagcga
     6901 tgcagcttgt ccagcgacaa ccgcagattg cagatacgat ttcggatcag atatctggaa
     6961 atatccatac gattgatact gaccgtgaag gaaatcgttt ggaaaaccct aagttcaaat
     7021 tcgtagtagc accacaaatg gtcaatggcg ttggaaccat ttcttttggc gtacttagcg
     7081 aaatcatttc tgatgtcgca caaaaaacaa tggtgatgaa ccaaaaacga aatatcttga
     7141 ttgaacaagt gaacctacat tatttgcggc tgatccaatt ggaaagcgaa ttagacattc
     7201 gtccacgtgt attggaaatc ggcagacgtt ccgctaaact ggatatcgaa gtgtttattg
     7261 aaaacaccat cgtttccaaa gcaatcgttg tttgtcaagt aatggaacgt tcttagaaag
     7321 caggagtgaa atgacagtac agcaagaaat agtagataca ataaaaaaat acgataaaat
     7381 cattatccac aggcatttgc gccctgatcc tgatgcatta ggatcacaag taggattagc
     7441 cgaactatta cgggaaagtt tcccagaaaa agaaatacgt caagtaggtg aaacgattga
     7501 agggcttcgc tttttagcag aaatgcaaga agttgaagat gtcttctacc aaggagcgct
     7561 agtcatcgtg actgatacag ctaattcacc cagaatcagt gatcaaagat atcagttggc
     7621 agaaaaactg atcaaaatcg accatcatcc caatgatgac ccttatggag atcttgtgtg
     7681 ggtaaataca aaagcaagta gctgtagtga gatgattgca gaatttgctt tgatgtttcc
     7741 tgaatcttta aagatgaacg ttaaggctgc acggttactt tatgcaggaa tcgtcggaga
     7801 tacagggcgc tttttgtatc cctccacgac gtcccgtaca ttagagattg cttcgatatt
     7861 gagaaattat ccatttgatg caagtgcttt gaacagagag attgaacaaa tgccgatgaa
     7921 agtcgctaaa ctttccggtt atctttatca aaatatccag gtggatgaaa atggtgcagg
     7981 aagaataatc cttccgcaag aaattcttga taaatatgga atcgatgatt cagagacagc
     8041 ttcgatcgtt tcacttcctg gagtgattga cgaagtgctg gcttggggga tttttgttca
     8101 gcagccttca gggtattacc gcgtacgttt acgttctaag gggccgatca tcaatgaatt
     8161 ggctaaacgc catcatggag gaggccatcc attagcaagt ggtgcgaatg caaaagattt
     8221 agcagaagta gaggaaatct ataaagagat ccaagatata tgccaatcgt ataagagcag
     8281 aaaaacagaa tgatacttcg ttcgaaaacg tgccttttgt agtaaaaatc acaaatgtat
     8341 cttttcaaga tcttcttttt ccgttacaat agtgctcact aaagatttta aaggagaaag
     8401 aagatgacat taccaaattg cccagaatgt ggctcagagt acacatatga agatcgaggc
     8461 ttgttgattt gcccagaatg cgggaacgaa tggaacaaag aagaacaaga aactgtcata
     8521 gaagacggat tagtggtatt agatgcaaat ggaaaccgtc tgttagaggg cgatagcgtg
     8581 acagtgatta aagacttgaa agtaaaaggt gcgtcaggtg ccattaaaca aggaacaaaa
     8641 gtcaagaaca tccgtttagt agaaggcgat cataatatcg attgcaaggt agaaggattt
     8701 ggaccgatga aactgaaatc ggaatttgtg aaaaagaatt aaagaatatt caaggtcttt
     8761 tcacattctt ttcctactac taatgataaa ataaagtaaa cgaaaaggag tgaaacgaaa
     8821 atgtatggtt atggaatgta tggtttttta gatccgacat ttcttttggt cattcttgga
     8881 ttagttattt ccggaattgc gtcagcgtac gtcaatagta ctttccgaaa atacgatcaa
     8941 gtgagaagca aaaacaatgt gactggtaca caagcagcac aatatatatt acaaagtcaa
     9001 cagataaata atgtcggtgt tcaacaaatt gccggagatc tcacagataa ctacaattca
     9061 ggtaataaga tgttgagttt gtctcaagca actgcacagt ctacttcagt tgctgcgata
     9121 ggtgtagcag ctcatgaatg cggacatgcg gtacaagatg cttcgggtta tgtcccattg
     9181 aagattcgtg cagcacttgt tccagcagct aactttggtt cgatgatttc gttccccttg
     9241 attatggtag gtgtattgct tagctggaac tctacgttaa tcaatatcgg gattttcgct
     9301 ttttctttag cattactttt ccaattggtg acattaccag tcgaatttaa cgcgtctcgg
     9361 cgagcaatcc aaattttgag tgaaggcgga ctactgacgg aagaagaagt accgatggca
     9421 agacacgtat tatttgcagc agcactgact tatgttgcag cagcgctttc gacattcctg
     9481 cagctgttgc gcttgatctt attgttcggc ggcaaccgaa gagattaaaa taaagaagtt
     9541 gtgaaatcag cgctttgatc tgagctaata ccgagagtta gctgattgaa taccatttat
     9601 ttggaataag aggatgtgac aagaattttg tcacatcctc tttgttttgt tctcataacc
     9661 ttttttcata tacagttcat gaaccgcttt tattaacttg ccaaataaca ctgtattgtg
     9721 cgttgtatcc agatagaaag tctccgtttc atctgaaatt ttctcatgct gatctgtaat
     9781 gatcaaatca gcatgttctg aatatgcggt aattttaaca gcatctttgc gaaataactg
     9841 ctgcaaatgg ctttgaagat gataatttcc tgtaaactgt ttggttatct gcaaatggat
     9901 gagtaactgc tctttcgttt ctgtttgtag taagtgttgg atcaattgac taaggtattg
     9961 actgatttgg tttctttccc cattttttga aaaaattgta tcgatttttt ctcttaattt
    10021 cttttcctgt ataaaagaac tagaatgatt ggacgtggct tctggaaagc aaagtgtaga
    10081 aaaactactg ctggattcac ccaacagttc gaaaaaaaca actgccaaca caagaaaata
    10141 aaaataaatt ggtattttat tttctaaatg gttgagagga aactgttgag ttaagtaagt
    10201 catcaattga ccgacttgtc gacaaataag gtttttgctt gtggaaaata aaaaaccaat
    10261 ctcctgtttt tgtcgaaaag agatttgatt tggaaaaaaa caatagaaaa aataattaaa
    10321 gtaggctctc tctgtttctg tctcttcaca agggcgactc actgaaaaag aagtaaagta
    10381 ttctgaataa tcatgtgtat gctgcaataa gtccatcaat tcagtgattt cagaagaagt
    10441 ttttggaaaa tatgcctgtt gtttgtttcg taatatgaat aaagttaaca gcaagtagat
    10501 atttttttct tgttttgaaa ttttttctat ttgctcatct gtactgttca tttttagtgc
    10561 atttaattca agtgaggaaa atggccaatc gttacctcca aatgtatctg aaagaaaaaa
    10621 gtaaagatag agacggatag ataactcatt tccttcaaga gtacagcaat tttttacaga
    10681 taggatccgt aaatggaatt ttattaagga atgattgagc tgttttgtca gtttttcgag
    10741 ataggagggc gatatataaa gttgttcaag taaatatttt tttggtacag cagtttgtgg
    10801 ataattgatt agtaacatca aatagttaaa acgattggat tcttttaggt agcataattt
    10861 taacttagaa aaaacagcta actttttagt ttgatcggtt tctttggttt ggatctctcc
    10921 tttatgatta gaataaataa attcatcaat caataaaaat tgcttgagtg atacatttat
    10981 ttttcggatc agttctttga ttgtccgttt tggaatatgt aagtcattgg ataattcttg
    11041 taaagaacaa ttattttttt gaatgaccat ttgtagaaca agtaactctt tttttcttgc
    11101 ttcaattagc ataaatacct cctttttatt ctgtttttgt atatagttag acaaaaactg
    11161 tgagtggaaa gtcatttcag tctgtgttat tctcacagag tgtcgccttc ttttttatat
    11221 aacgttattt aatttttttg ttaccttgtt tattctattg tttatttcct agggtatttt
    11281 gtcaagatat tcttgttttt aaggcggaaa aattgattt
//
LOCUS       DACCVH010000090        11087 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.090, whole genome shotgun sequence.
ACCESSION   DACCVH010000090 DACCVH010000000
VERSION     DACCVH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.090"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            158..973
                     /gene="thiD"
                     /locus_tag="IVV98_002430"
     CDS             158..973
                     /gene="thiD"
                     /locus_tag="IVV98_002430"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP7808027.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1302..2753)
                     /gene="cls"
                     /locus_tag="IVV98_002431"
     CDS             complement(1302..2753)
                     /gene="cls"
                     /locus_tag="IVV98_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP7808028.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3094..5760
                     /locus_tag="IVV98_002432"
     CDS             3094..5760
                     /locus_tag="IVV98_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7808029.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6124..6876
                     /locus_tag="IVV98_002433"
     CDS             6124..6876
                     /locus_tag="IVV98_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7808030.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(6898..8052)
                     /locus_tag="IVV98_002434"
     CDS             complement(6898..8052)
                     /locus_tag="IVV98_002434"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP7808031.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8237..10678
                     /locus_tag="IVV98_002435"
     CDS             8237..10678
                     /locus_tag="IVV98_002435"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP7808032.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(10835..>11087)
                     /locus_tag="IVV98_002436"
     CDS             complement(10835..>11087)
                     /locus_tag="IVV98_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808033.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3593 a         1975 c         2382 g         3137 t
ORIGIN      
        1 cactattttc tgatttattg caaatgtttt ttcaaataaa tttgattacc aagaaaaggt
       61 agtggtatat ttactgaggg atactttgaa aaacatatga tagaaacagt aacagtatta
      121 tgaaaaatct ttttataaaa atggaggaat cgatttgatg gaagatcagt atgtacaagc
      181 aatgacgatc gcaggatcag atagcgatgg aagcgcaggg atgcaagcag atatgcatac
      241 attctttaca agaaatgttt acggtgtttc tgtcatgacc gcatgtgttg caggtaattc
      301 ttacggaatc ggagcaagtg tgacattgcc aacagatttt atcgacaaag aatttgaact
      361 gattgcgaag gactttcaaa tacgtgcagc taaaacaggt atgctagcag attcaaagtt
      421 gattgagaca gttgtaaaaa attaccaaaa atatgatttt ggaccattag tcgtggatcc
      481 cgtaatcgta acgaaacatg gaaatctttt actagaagaa tctgctttgc aaagcttgaa
      541 agaaaagctt gtccctttgg ccgaagtact gacacctaat ttttatgaag cagaaaagct
      601 gactggacgg acattagcag ctgaagaaga ttttgtgcaa gcagcaaaag aactgcaaga
      661 tatgggtgca aaaaacgtta tgatcaaagg acatcatgct aaaaatgcgc agcaagaaac
      721 agtcaatgac tacgtattgt tcgaatcagg aaaatcattt tggttaaatg caccatttta
      781 tcctaccgac cggatcaacg gaactggcga ttcgctatct gcatgtattg cagctgagtt
      841 agcgaaagga aaaacagttg aacaagcgat ccgattggca aaagactatg taaaccgtgc
      901 aattcgtgaa gaaataaatg tagggcacaa atatggcccc atcaatcatt gggcagctgg
      961 tgaattagag taaaagaaag aagttgtgaa aaagttgccc tgcatcaagt aataagaaca
     1021 gccaagtaaa aacagcttct tatgttttta acttggttgg acttattacc gcagatgcaa
     1081 gcttttgaac accgtttaag aaagaggtcg tgagcctgcc gtccagctcc gagtcacaag
     1141 gaacaagttc aaaaaacagc ttctcatgtt tgttgaatat tgtgacttgt gaccgaggag
     1201 ttggcaggag aacaccgttt gttcggaaga agggactgtg acaagatttt tgtcacagtc
     1261 cctttaatct tagtatattt ttctctactt gaataaaaaa attataggat tggagaaaat
     1321 aatcgagaaa tttgttgctt gaataatagc cagttagaca tttccttgac tgtttcagtt
     1381 gtcatggatg aacaatgtgt ctcatcttct ttgaactgag tagcaagttc ttctaaaaac
     1441 tcaggatcgt aaatgacagc acttgtttca aaattcaatc ggtagctacg aatatcttga
     1501 tttgctgaac ctaccatgca gatttcatca tccattatca atgtttttgc atggaggaag
     1561 ccgttctcat agacaaggat ttgtacattt tccttgatca gctgccgagc ataatattgt
     1621 gttgctcgat aaataaaagg atgatccggt ttgttgggaa tcatgatttt cacatctaca
     1681 ccagaggcag ttgcgatttt taaagcagca atgacacttt catcaggaac aaggtaaggt
     1741 gtctgtatcc aaacacgttt tttagcagaa gtaatcaatt tgataaatga aagcttgatt
     1801 tgttcccttt cgttattcgg tccgcttgaa acaagctgga tggatgtatc agcaagctta
     1861 gattcatctc gatctgcttt tttaaagaaa taattcaaat gatagccgac ctttttttct
     1921 tcaggtaccg agacgttcca gtctgttaag aagcgaagct ggagcaaaga agaagcggca
     1981 ccgaaaatcc gtatatgcgt atcgcgccaa tagccgaatt tttttgttgt atttacatat
     2041 tgattggcaa tattgaaacc accggtataa ctaatctttc catcgatcac aacgattttt
     2101 cggtgatcat ggtaattcaa tcggaaacga agtaatgccc tttgtgaggt aacaaatgta
     2161 tggacatgtc caccattttt gattagacga ttgaaatctt ttgcttttgt gccatgagag
     2221 ccaaatgcat catataatat tcgaacttcc acgccttctg cggctttttc ttctaaaaca
     2281 tgtaagactt gctggccgat attatctgtc acaaatgcgt aatattcgat atggatcgaa
     2341 tgtttggctt tttttagatc ttgaagcagt gaatccaatt tctcttgtcc gtctgtgaga
     2401 agagtgacag aattcattct tgtcagcggc atacgattta atgaagagaa gaagtcaaca
     2461 aattgctgtt tgtctttatc gcccatgtca ggatcgtaat gttcaatggt atctcctcta
     2521 aaagactgaa agttttctaa ttctttcaag tcactttgtc ggagatagaa ttttttctta
     2581 tccgttaatc cacgtccgaa aaataaatat aatacaaagc ccaccccagg aagggcaaac
     2641 aatactaaga gccatgccca aatggctgct acatctcggg gtttgatcaa aatagccacc
     2701 aaagcaataa gtgcatttaa tagataaagg gcggttataa tactagatac cacaaaaatg
     2761 ttcctcctta catacaataa cattagtata gcatgataga agaaagaagc ctaccaaggt
     2821 gaatatactt ttcactcctt tcatgaaaat gtaggtaaat cgggctaaag tagttgcttt
     2881 ttgtaggtta ataaggtagg atattagtac agttgaatat ctccttaggg gagtaaccgg
     2941 caacgtttgt tgcgataata tcaacagtaa gttaaccaaa tggttttctg gtattgtatg
     3001 aaatggtgag acctaagaca aatgcgtatt tgtcttaggt ctcttttttt tcagacagga
     3061 ctagggccaa gatcaaaaaa tgggggatga aatttggaaa acaaggaaca agcacaacaa
     3121 gcggtctata aagaaacgat cgactcgttg atgcagcaaa cgcagagctc aaccgatgga
     3181 ttgagcacca cgcaagcgaa ggaaaaatta gaaagagatg gcttgaacca gctaaaagaa
     3241 aagccgaaga agccaacttg gaaattgttc ttagaaactt tcaaagatgc aatggttatc
     3301 gtattgctga ttgtcgcact gattcagatg gtcatgggtg actacatcga attcttagtt
     3361 atttttgcag tattgatgtt gaattctata atcagtgttg tccaaacaaa aaaagcagaa
     3421 ggttctttag aagcgttgaa aaacctttca gcgcccgatg ctcgagtgat tcgtgatggt
     3481 aaggaaaaaa cgattccggc aaacgaactt gtggtaggag atatcgtgtt gttagacgca
     3541 ggcgattatg tacctgctga tggacgttta ctagatgcgg gatcattaaa agtagatgaa
     3601 ggtatgctga caggagagtc gacttctgca gaaaaagaag taacggatat cacaagtacg
     3661 gtaccaatcg gagatcgtac aaatatggta ttcagtggaa cgatcgtaac ttacggacgc
     3721 ggtaaattct tagtgacttc aactgggaat aatacggaga tcggacaagt tgctggcctt
     3781 ttggaatcaa caactgagca agtcactccg ttacaacgag gtctggataa attcagtaaa
     3841 aaactaagtt tggctatttt ggcattgtct ttattgattt taggtatcca actgtttcgt
     3901 atttatcttg gagaaggtac aggagatatg actgcagata tcgtcagcgc agtgatgttt
     3961 gccgtagccg tagccgtagc tgctattcca gaagcattac agtctatcgt aacaatcgtg
     4021 ttatctttgg gaacgaataa aatggcaaaa cgtcatgcca ttattcggaa gcttccagca
     4081 gttgaaacac ttggttcgac aagtatcatc tgtacagata agactggtac attgacacaa
     4141 aacaaaatga cagttgttga ctacttttta ggtaatggcg atactgggga tttcacaaat
     4201 gacccttcaa aatggacagc tgacgaacgt cgcttgatcg aaatcagtgt tttagcgaat
     4261 gatgcatcga tcagtgaaga cggtactaaa ttgggcgacc ctacggaagt agcgtttatc
     4321 gactttagtg aaaaattaaa ccagccttat caggaaatcc gaaacaacta cccaagacaa
     4381 gcagaacttc cttttgactc agatcgaaaa ttaatgtcta ctggacacac aattgataac
     4441 aaaaattact tgtttgttaa aggcggacca gatatcgtct tccaacgcag taaaaaagta
     4501 ttgctaaatg gtgaagtcgt tccgatgacg gatgaattga tgaaaaaatt ccaagagcaa
     4561 aatgaagctt tttcaacacg cgcattacgt gtactagctt ttgcttaccg tccacttgat
     4621 aattttgatt tatcatttga agatgaagac gatttgatcc ttgttggttt gcttgctatg
     4681 atcgatcctc cacgtgctga agtgactcag gcggtaacag aagcaagaag tgcaggaatc
     4741 aaaacaatca tgattactgg tgaccacaaa acaacagctg ttgctatcgc aaaacaaatc
     4801 gggatttttg aagaaggaaa cctggctttg accgggacgg aactagatga attgacagaa
     4861 gatcaactaa acgaagtttt agaaaaagtc actgtttatg cacgtgtttc acctgagaat
     4921 aaaattcgta tcgttcgtgc ttggcaaaat aaaggtcata tctcagctat gacaggtgat
     4981 ggtgtaaatg acgcaccagc attgaaacaa gcagacatcg gaattgctat gggaacgggt
     5041 acagatgtgg caaaagatgc agcagcgatg gtattgacgg atgataactt tgcttctatt
     5101 gtcagcgcag tagaagtagg acgtaatgtg tttgataata tcaagaaagc tatttcttat
     5161 ctatttgcag gaaatttagg tgcgatcatt gcgatcatct ttgccttagt tgctgactgg
     5221 tccaatccat ttacagcatt acaactgttg ttcatcaatt tagtcaatga ttcactgcca
     5281 gcaattgcat taggtacaga aaaagctgaa cctgctacga tgaaccgccc gccaagagat
     5341 ccaaattcag gaatctttac ggacaaaaca ttgatttctg taacgtatcg tggtgtgctg
     5401 attgggattg ctgttatctt tgctcaatgg cttggcatgc agcattcacc tgaattcggt
     5461 gtagccatgt cattttcaac attgatttgg tgtcggacat tgcaaacatt cccagcacgt
     5521 tcaaacacac aaacagctat ccaagcaggg ttcttctcta acagaagtgt cttactagct
     5581 gtagttgtat gtagcgcgct ttactgctta acaatgatcc caggactgaa agaagtcttc
     5641 tctatcccat cagcatttgg attgacagaa gtctttacat gtatgggaat cgcacttgtg
     5701 acaattgttt tgatggaaat cactaaattg atcattgtac gagtacaagg aaataaataa
     5761 aacgaatcaa cgaggttgtg agcctgccgt ttaattctga gtcacaaggt gcaatttcaa
     5821 caaacagctt ctcatgtttg ttgaatattg tgacttgtga ccgaagagtt ggcaggagaa
     5881 caccgtttaa ggaagaagtt gtaaaatcag cattttgagc taatactgag ggtcatctga
     5941 ttggacactg tttattcgga aagagggact ttgacacgac tttggtcaca gtcccttttt
     6001 ttatttatga tagacggaaa gccaatcatt ttattattca tcaaaagaga tagaatagat
     6061 aaaagaggag aatgatttat tccgaaaagt gaaaacatat aacaaaaaat tagaggaaat
     6121 caaatgaatg aaaaagaatg ggatgaattt gctgaagaat attatgaaat ccagcaagaa
     6181 tcgcaagtaa ctattgctga agatgtaaaa aattatctga aaacggagaa agtcctgcct
     6241 gctgaaacag cagcagacgt tgctggagga tctggcagat ttctttcctt agcaaaagaa
     6301 attaatcgct atgatttgat cgatttttct tcaggaatgc tagaaaatgc aaaaaaagaa
     6361 gcagaaaaaa atgagttgcc aaatgtttcc tttatcaaac agtcgttaga agaatttatc
     6421 caatcaaatg agacatatga aatggttttt acagcagcaa atccagcatt ggtacatctt
     6481 attcaattag aaaaattgat gaaaaagtca agcaaatggt gcgtgataat cagagtagtg
     6541 gaatcaatcg atgatgtttt ttatcctatc gaaaagcaac taggaatgat agaagaagat
     6601 cctaatacat cgccagttgt aatggatcaa tttgaaacat acttaattga tgaaggattc
     6661 aaagtgaaga aaaaagattt tacttatttt acacaggaat caattactga agaattgatg
     6721 aagctatact atgacgcgta cgcaaaagat cctgttgtga ccaggtacat tcgcaaacta
     6781 ttcagtgaaa aacgagaaat ccttagtacg actaagctga cctatagact gctcctttgg
     6841 tccgcagata aaaaaagaac ctttcacgac tcgtgaaggg ttctttttat gattttatta
     6901 tattttgtag taacgaatat cattttcgat ctttgtaatc gaaaaaggta catctgaagt
     6961 atattctgca cattctccgt gttcaggaag cgtctcactg aaaatcgttt catattcgtc
     7021 aacagtgatc cgtgttcgag aatctagcat ctcttgatga gattgtgcga agagatattc
     7081 ttgatagttt tcttccagat aacctgtaaa aaattcactt actgcaccag aaccgtagct
     7141 gaatagaccg atgcgatctc ctggctgtag tgatttcgaa ttttccagta gagaagttag
     7201 ccccaggtat aatgaaccag tgtaaagatt accgattcgt cggctgtaac ggatgctttc
     7261 ttcatagcga gccataagac gttcctgatt ttcttcgtct gtttggtcta atacgctttg
     7321 caatgccttt tttcccatct tagtatacgg aatatggaaa gcaatcgcct gataatcttc
     7381 gagtcctcga cccgacaatt ctttatgtcg attccaaact ttttggaatg attcgatata
     7441 cgtagaatta gataaaggac catcaacaac aggaaattcg ctataatctg gacgccagaa
     7501 atcatagata tcttctgtca gaaatacgct gtcgtcttca atcgataaaa tacgcgggtt
     7561 ttgagtgatc atcatcgcaa cagcaccgac accttgcgtc acttcaccac cgcttgccaa
     7621 gctgtaacga gcaatatcac ttgctatgac tagtactttt cgttctggat gatttttgac
     7681 atattctttc gccatgtgca aagctgcggt gccaccgtag caagcctctt ttacttcaaa
     7741 agaacgagca aaagattgga ttttcagtaa atggtggata attaccgcac tcgcttttga
     7801 atgatcaatc ccggattctg ttccgacgat gaccatgtcg attagctcac ggtctttttc
     7861 tgttacgatt ttgctggcag catttgctcc tagtgtaatg atgtcttcat ttgcacgatt
     7921 gactgccatt tggtcttgac caatccctat atggtatttt gcaggatcat ccccacggct
     7981 ttctgccaac tctgtcatat ctaaatataa attaggaata aaaaaggaaa gacgatcaat
     8041 ccctattttc atttcaacac ctctttactt atgataaaaa acttacttta ctaaggtatc
     8101 ataaaaagat taaaagaaat ataaaaaaga gaatatttaa ggattgttaa aatttaatct
     8161 tagaaaaaaa taactggaac aagagctatt tgtttttaca gcaaagaatg gtatattttt
     8221 gtaggaggtg gcttacttga aagaagtcgt tatgatagat gctgcaagaa cgccgatagg
     8281 aaagtatcgc ggaagtttaa gtccatttac tgcagttgaa ttaggcacac ttgtgactaa
     8341 aggattatta gataaaacaa aactgaaaaa agataaaatc gatcaagtaa tatttggaaa
     8401 tgtcctgcaa gctggtaatg gtcaaaatgt tgccagacag attgctttga acagcggtct
     8461 ccctgtagat gtcccagcaa tgacgatcaa tgaagtttgc ggatctggta tgaaagcagt
     8521 gatcttagca cgccagctga tccaattagg tgaagcagaa cttgtgatag ccggcggaac
     8581 agagagtatg tctcaagcac ctatgctgaa acagtatcag tcagaaacaa atgaatatgg
     8641 tgaaccaatt tccagtatgg tcaacgacgg attgactgac gcattttcaa atgcacatat
     8701 gggattaacc gcagagaatg ttgcaacaca attttctgtg agcagagaag agcaggatcg
     8761 ctatgccttg tcgtcccagt tgaaagcagc acatgctgtc gaagccggtg tattttctga
     8821 ggagatcatc ccagtcaaga tttctgatga agacgtgtta tctgaggatg aagcagttcg
     8881 tggaaatagt acattggaaa aactgggcac gttacgtaca gtattctcag aagaaggaac
     8941 tgtaacagca ggaaatgctt ccccgttgaa tgacggtgcc tctgtggtga tccttgcatc
     9001 caaagaatac gcagaaaata ataatctgcc ttatttagca accatcaaag aagtagcgga
     9061 ggtcggtatt gacccaagta tcatgggaat cgctccaatc aaagccattc aaaaattgac
     9121 agatagatca ggaatgaatt tatcaacaat cgatcttttt gagatcaatg aagcatttgc
     9181 agcttcttct atcgtagtta gccaagaact gcagttagat gaagaaaagg tcaatatata
     9241 tggaggagca atcgcattag gccatccaat tggtgcaagc ggtgcacgta tcttgactac
     9301 attagcttac ggattgcttc gtgaacagaa gagatacggt attgcttcat tatgtattgg
     9361 tggaggttta ggcttggcag tcttgttaga agcgaatatg gagcaaacac ataaggatgt
     9421 gcaaaaaaaa aagttttatc agcttacgcc atctgaacgg cgcagtcaat taatagaaaa
     9481 aaatgtattg acacaagaaa ctgcgttgat ttttcaggaa caaacacttt ctgaagagct
     9541 ctccgatcac atgatcgaaa accaagtgag tgaagtggaa atcccaatgg ggatcgcgca
     9601 gaattttcaa atcaatggca agaaaaaatg gattccgatg gcaacagagg aaccatctgt
     9661 cattgcagct gcaagtaatg gtgcaaaaat ctgtggaaat atctgcgcag aaacacctca
     9721 gcggctgatg cgagggcaaa tcgttctatc aggaaaatcg gagtatcaag cagtgatcaa
     9781 tgcagttaat catcgaaaag aagagctgat tctttgtgca aatgaaagtt atccttcaat
     9841 cgtgaaacgc gggggcggtg ttcaagatat ctctactcgg gaattcatgg ggagtttcca
     9901 tgcatactta tctattgatt ttttagtgga tgtaaaagat gcaatgggcg ctaacatgat
     9961 caactcgatt cttgagagtg tggcaaacaa gttacgggag tggttccctg aagaagagat
    10021 tctattcagt attttaagta attttgctac agaatcattg gcttctgcct gttgtgaaat
    10081 cccattcgaa cgcttaggga gaaacaaaga aatcggtgaa caaattgcca aaaaaatcca
    10141 acaggcaggg gaatatgcga agcttgaccc ttaccgtgca gcaacgcaca acaaagggat
    10201 catgaatggt atagaagctg tagtggcagc tacaggaaat gatacacgtg cggttagcgc
    10261 ttcgatccac gcctacgcgg caagaaatgg attataccaa ggattaacag actggcagat
    10321 caaaggggat aaactagttg gaaaactaac ggtgcctttg gctgttgcca cagtaggcgg
    10381 agcttccaat atcctgccaa aagcaaaagc atctttagct atgttagata ttgattcagc
    10441 caaggaacta gcacaagtaa ttgctgcagt agggttagct caaaacctgg ctgctttgcg
    10501 tgcattagtt acagaaggaa tccaaaaagg ccacatggga cttcaagctc gttcattagc
    10561 gatctcaatt ggggctattg gtgaggaaat cgagcaagtt gcgaaaaaat tacgtgaagc
    10621 agaaaagatg aaccagcaga cagctataca aatattggaa aaaatccggg aaaaataaaa
    10681 aagcaatatc tttagaagaa taaagcaaga tttacagtta ttttatttac tgcagatctt
    10741 gcttttttgg ctcttcgtca aattgtgttg gcgaagacaa atttgaataa aacttagtcc
    10801 gatatgcggc gcgttctgtg cgccgcatat ttttttagtt ttcaaagatc agaccttgtt
    10861 gtaaatagat ccgtgcccga aagttataaa agttgcgata accaaacgca attcgtttaa
    10921 tcagcttgat cttgttattc agcccctcag tgacgccgtt tgagtggggc accttaaagg
    10981 catttgaaat acccgattgg tagcgatgga agatcgtgaa tttcttttta aacgactgag
    11041 gtaacgtaga tgaaattgtt ttaagggttt cttgaaagcc ttccgta
//
LOCUS       DACCVH010000091        10999 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.091, whole genome shotgun sequence.
ACCESSION   DACCVH010000091 DACCVH010000000
VERSION     DACCVH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.091"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            835..1308
                     /locus_tag="IVV98_002437"
     CDS             835..1308
                     /locus_tag="IVV98_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP7808034.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1317..1544
                     /locus_tag="IVV98_002438"
     CDS             1317..1544
                     /locus_tag="IVV98_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7808035.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2180..2551
                     /locus_tag="IVV98_002439"
     CDS             2180..2551
                     /locus_tag="IVV98_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808036.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2807..3049)
                     /locus_tag="IVV98_002440"
     CDS             complement(2807..3049)
                     /locus_tag="IVV98_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7808037.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3081..3983)
                     /locus_tag="IVV98_002441"
     CDS             complement(3081..3983)
                     /locus_tag="IVV98_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7808038.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3996..4184)
                     /locus_tag="IVV98_002442"
     CDS             complement(3996..4184)
                     /locus_tag="IVV98_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP7808039.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4198..4761)
                     /gene="amaP"
                     /locus_tag="IVV98_002443"
     CDS             complement(4198..4761)
                     /gene="amaP"
                     /locus_tag="IVV98_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP7808040.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4799..5692)
                     /locus_tag="IVV98_002444"
     CDS             complement(4799..5692)
                     /locus_tag="IVV98_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7808041.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5770..6707)
                     /locus_tag="IVV98_002445"
                     /pseudo
     CDS             complement(5770..6707)
                     /locus_tag="IVV98_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            complement(6741..7091)
                     /locus_tag="IVV98_002446"
     CDS             complement(6741..7091)
                     /locus_tag="IVV98_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7808042.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7124..8026)
                     /locus_tag="IVV98_002447"
     CDS             complement(7124..8026)
                     /locus_tag="IVV98_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP7808043.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8019..8876)
                     /locus_tag="IVV98_002448"
     CDS             complement(8019..8876)
                     /locus_tag="IVV98_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP7808044.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9210..10019
                     /locus_tag="IVV98_002449"
     CDS             9210..10019
                     /locus_tag="IVV98_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7808045.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10059..10556
                     /locus_tag="IVV98_002450"
     CDS             10059..10556
                     /locus_tag="IVV98_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7808046.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
BASE COUNT         3215 a         2067 c         1861 g         3856 t
ORIGIN      
        1 aataaaaatg aggtatgtcc tatgatgaaa agattgtact attcattgat cataacgatt
       61 ggctatttga ttgtatcaaa tctaggaaat atggtatttg gtatcagtaa agaattcagt
      121 tggactacta cattatggga atctctattc tttttcatct tcgtattttt gttacaaaat
      181 tatcgaaaaa aataaacatg tgccatctat ctgttggcac atgttttagg atttatggta
      241 ctttttattc ggcaatccat tttatttttc tacttcttct taatacctct aacacttttg
      301 atttataaac taatccaatg catctacttg cgcttattaa gctatttcag ctagatagta
      361 ccaccccatg cgtcaatgct tgattttcct tttgtataac attgtataag caataaagga
      421 caaataagtg gtgattacac caaaccattg aataagaaaa attctgatac gtaaataaac
      481 atgaacttga aaaaattaat gaatcggtta gctactacgt agttgtcttt tttctcatac
      541 agttctgtta acttacactt ctcttcgcta gataataaaa aatcctccaa ctgtattgtc
      601 caatataatc ccaggcatct aaactagcat tatagaagag acacacatag aatctaaaat
      661 aactggtttt aaatgtttct tacaatcaaa aaaagctgtt aaatgcactc cacaccttca
      721 tactctatca ttttttataa acgatatatt tttattgttt ttcgataaaa aatagttgtt
      781 ttacaataat tattctgcta tattttagct atcaaagata aaagagggat aaaaatgaaa
      841 tttaaaacat tgctattaaa atttgtcgtt ttaggtataa gtgccgtatt tattttgttc
      901 ggcgtacttt tttatactca gatcgctaca agcgaaaaag gattcaattt tgattggcag
      961 accacattat ttgtttctgt catttacttt gcccttctcc tagggatcgt tattgcttat
     1021 ttcttattga aactattgaa aaaaatcgaa gataaccaag ctttttccac tcaaagctta
     1081 aacatactaa aaaaaatcga acgaaccatt ttgtttattg gtttcgcctt ttttggctta
     1141 cttcctaaat ttatgaaagt agcggattta gacgatgctc caggtttgat gttggtagga
     1201 atcgctgtcg tattcattcc ttttgcagta tacacattaa caagcgtgct ggaaaaactg
     1261 cttgaacatg cgattttact taagacagat catgatttga cagtgtgagg tgcgacatgg
     1321 caattatcgt taatttagat gtagtattag ctcaaaaaaa aatgagtgtg actgaattga
     1381 gtgagaaagt gggcattacg atggcaaaca tctctattct aaaaaatgga aaagcaaaag
     1441 ccatccgttt ttccactctc gaaaaaatct gccaagtttt ggagtgtcaa ccaggtgatt
     1501 tgttgaccta taaaaatgac tcgaatacta taccagaaga ataaaataaa gtagaacaaa
     1561 cagtaaataa aaaataatct gaatgataga tgtgtgagac ttttagaagt tatttacgtc
     1621 tattattcag attttttatt tcgattgaat accgttttat ctataaataa gatatgtact
     1681 gactcataca aagggggcct tttcttctcc atgtactatc acttttcctg atacaactgg
     1741 tttcctgtta cgttgtagtt ggatctgctt ttagtataat actttattca ttccaccaga
     1801 ctgatagcag tttgagcagt ctaaataatc atgtagtatt acaggccatt ctgtttcata
     1861 ccttgaagtg cttaaaactt cagctaatgg cccattgtgt taactcttac tccattcttt
     1921 tttagtaagc tcccatatat actgtaaagc cttctatata ttatgtcatg ttgcttttta
     1981 acatttacta tgtagttttg ataaaatgat ttgaataaca gtgatggaca attctttttt
     2041 atttttaaca ttattttgat aataatgatt atttatttaa aaatacatta gataacattt
     2101 gttacgacac gaaaaagctt cacaaacaaa tatcgttatt ttaaaatgag ggcgaactca
     2161 cacaattagg aggaatagta tgccatttat tgtttacttt tttctttcat tactcgtgat
     2221 ctatattcca ttaccaacat ttttcctgct cgtcaatcgt ctagcagagc aacatgatac
     2281 gattgctgct cttacgaaac tttgtttact tctatttgtt tgtctagatt actttacgag
     2341 ctattattgg ctaaaacaga caagagtaaa aaagagatat tatttcttcc ttgtcttttt
     2401 caatctcttt gagtttctga tccattgctt tttacttcat cagtatcata cgatccattt
     2461 gtggatcatc tgggttttca aagtggtcgt attattttgt atgttcacct ttcctatctc
     2521 aagaaaattt agggaggcat tgttttatta aagaagcttc tctgtatcaa taaagacaca
     2581 tttaaggaaa aacttttaaa aatctaattg ggaatttgcc cgcataaata agaggctgtg
     2641 acaaaagtct tgtcacagcc tcttattccg tataaacagt gttcaaaagc ttgcatcttc
     2701 gataatatgc ccaaccaaat gaaaaatatg agaagctatt tttgtttggc tgttcttatt
     2761 acttgatgaa gaacagcttt ttcacgacct ctttttaaaa gtctttttac agttttcgag
     2821 caaagaatga tacgattagt actaaaatga tggcaccaat caatgatggc acgattgcca
     2881 ttcctgcaat acttggtccc caagaaccta ataatgcttg accaagtgct gatccaacta
     2941 aacctgctac gacatttgca ataatcccca tcgaagaacc tttattcgtg attgctcctg
     3001 caattgctcc gataattcct ccgacgataa gtgaccaaat aaatcccatg tttcgttcct
     3061 cctaatgttt tacttcctta ttactgaacc cgtggttctg tattttcttt tactttttgt
     3121 gcgccgcttc cagctgctga ttttacttta tctgtttgat tcgaagcaaa ttcaccggtt
     3181 tttttcgctg cgtcagttac tttgtcttgc accgtttctt gatctttttc aaattcttct
     3241 tttgttttga tgtccactac gttagcgttg acttcgatca cttctaaatg tgtcatattt
     3301 tttacttctt tgccgattac ttcttgcatt tcttcaaaga ttttttcgat atctttgcca
     3361 tattccacaa tgacatccat atcaactgct acttgttttt taccgacttc tgtttcgatc
     3421 ccagccgtta cattatctgt attcacaagt tttcctgcca cattagagaa gaaaccaccg
     3481 tttgcagata ataaaccgtc tacttgttca attgcgattc cgatgatttt ttgcacaact
     3541 ttatcttcat aattcagctc accgcgcatt gaatcttcct gttcagaatc atgctttcct
     3601 tggttatttg tatgatcaga accaagtttt ccttgtccgt ttgtgtggtc agaactaagt
     3661 ttttcttgtg ctttcgcatg gtcagaagga tgtttttgct cttccacagg tttagaagga
     3721 tcgattgcat catgttgttc tggaacttta gattctggag ttcctggatg atgaggtgca
     3781 tgcttttctg catcatgttt cttctcttct actccttgtt gaacgttagg gactactgga
     3841 tctggatgtg cagatactgg tgctgttttg ttcttttcat cgttcacacc atttgattgg
     3901 tttggtgtcg ttgggtctgg atgtgcagac actggttttt ggttgttcat tttattgtta
     3961 ttatttttgt tattgttatt catggatgtt tcctcctaag atttaaaata gtgatctaag
     4021 attttcgttt gtttcagata aaaaccgata gcgacgccga tcgctgccat gatcaagatc
     4081 aataaggtct tgaaaaagcc cacggtgatc cataaaacgg ctaatatcaa tccaagtacc
     4141 ccaaagatga tagggagctt gtatgtcgaa aatagttctt tcatttttgg tcccccccta
     4201 ttctactcgt ttgcggtcat tgcttcgttt agctggttct tcaaagcctg tgtatttcac
     4261 cgatactttc actggctctt ttgttcccaa tatgtgttgt acttcatttt cgatttcttt
     4321 catcaatgtt cctgttttac caatgagtgc tgaagttcgt ttcaactccc cttttacatt
     4381 gacggcgatc ttgtttttcg ttgctttgac atttactttt ggtgaatgga tgaattcatc
     4441 ttcatgcaag tgagaacgaa ccattccttc aattgctttt ttatccaacg tcaactcccc
     4501 atcaccatgt ttcagtagaa agtttccgat tgtttttgga taaaacagga aaacaagtaa
     4561 cgtgataatt gtcaaaatag caaatgcaac ggcaagccaa aatacatatt gttgcacgta
     4621 tgaattagtg atggaaaaga atcgaaactt ctctagctga aaaggcaatg gataggttgc
     4681 acttaatagt atcgcaaaca aaagcacaga tagcaaaagt aatgttccga tcactccgat
     4741 cgtttttaca cctttattca ttttcgcacc tcctcatagg ggtgaaacga tcaacttctt
     4801 ataagttgat cgcttctcca ccagttactc cgtaaatttg ggctgtaaca taacttgctt
     4861 tattcgatgc taagaaaaca taaactggtg ctaattctcc tggctgacct gcacgttcta
     4921 gtaaactttg ctgaccaaat tcagggatcg aatcagaagg ttgtccttcg tctagttgta
     4981 atggtgtcca gattggacca ggtgctacac catttacacg gattccttta ggtgcaagct
     5041 gttttgctaa accgatcgta aagttagcga ttgaagcttt tgttgctgcg taatctaata
     5101 aatgttcgct tggattgaat gcttgaacag aagttgttgt tacgattgct cctcctgctg
     5161 ggatatgcgg aacagcttct ttcactaaag caaacatagc gatgatgttt atcataaatg
     5221 tgtctttgac ttgctcaagt ggtaactcag caatagactg acaagaaatt tgctgtcctg
     5281 cgtttagtac catcgtatct agcccgccaa gttcactcac ggctttatct atgatttctt
     5341 taggtgcttg ttcgtcacga agatcaaaag gtagtaagac aatcttacgt cctgcatctt
     5401 tcacgtattt tgctacttcc tctgcatctt tttcttctcc tgggaagaat tgaagagcga
     5461 tatctgcccc ttctctagca aatgcaatcg ctgctgcacg accgatccct gaatctccac
     5521 cagtgattag tacacggcgg ttttctagtt gattattgcc ttcataggat tcttctccac
     5581 aatcaggaac aggaatcata ttctgctgta aagctggtgt atcctgatct tgtttaggaa
     5641 atttctccgt atggtacaag tttcgcgggt cgattaattt tggttctgtc attgctgtat
     5701 tcctcctagt ttttaaattg tattgccaaa acaaatttct ttgtttgata cctgttttaa
     5761 atagattctt taatttgtat aatctttccg gtataaatgg taacctaaaa ctactgctgc
     5821 tatcaaagag ccaaagacta cgagtataaa gcctagagca gaacttttac ccggtaatcc
     5881 tcctgtattc attccccaaa tccctgcgaa caacgccgga acggaaatga ttaatgcagc
     5941 tgaatctaga tatttcatga tatgatttag attattgtcc atcatcccgt tgaatagatc
     6001 accaatactc tctaataaat ctcgatagat ctcgatcatt ttttctgttt gtcgctgtct
     6061 caaatggaca tcatagagta gctgttcatc gtctaaacgt ttgatgaaag tttcagaatt
     6121 ccataattga tccattgttt cccgttgatc tcttaaggta tgatcgatat atacgatgtc
     6181 tctttcaaga tctgcctgtt tatacagttc ttcattttcc gttgttttac gagctgcttt
     6241 atccaaagcg tcaattcgct ttttcatctc tcttagttct ttcacgtaat gggtgtaaat
     6301 atctaataat gtatacgtga tgatcttttc aaacgagttt aaatgatttc catgctttgt
     6361 cagcagccga tccacaaatt cggtttttct atcgatacaa gtaatcaaga gattatcgga
     6421 aagtacaaaa gatattggcg ttaatttttt tcgatacgat tatctgactg atctagatta
     6481 atcactacca aagaaaatgg atgctctagt ttcgtctcat aaaggcgctc catccgagaa
     6541 acttcttccg gatattcggt tcctacgaaa atatcatcag gaagctcgaa ttcttcgatt
     6601 gcttgctcaa tctcttcggg ctttgcacta tcaagtacga gccaattata ttttttttca
     6661 tctgtttcta ttacattctt ttcttcatcc acaaagtagt atctcaatgt atacctcctt
     6721 tttggacttt ctcgaaacta ttagctgaag aagcagttct ttaatttgat attataatcg
     6781 agtactgcga tttcattttc taatgaaaag ctgtcaagct gtttgttgaa gtccatgttc
     6841 aatcgtttac cgaaataatt ttgctctaat ttagatgtat agatgtccaa taatggatgc
     6901 tcgattttag tcgcatattc tccaaattcc gaaacaaaag gaatgatttg aaaaaagctg
     6961 ccttttgcaa aagcaccttt gtcccttaga aatggatcgg aatcattgat aagcgcgagt
     7021 gcgatttttg tattttcccc aaccttttca attaacgtct ctactgcatt tttagacatt
     7081 gtaatttcca ttcctactcc ccctcttcag ttgtggtctt ctattattta acaactacat
     7141 ctgtttttgg ttgaactttt gcatattttg gatatttagg gaatttagct acacaacgga
     7201 aagccgtcat ccctgcatat ttttcgtaat atttcttcgt tggcccttca aaatccttgc
     7261 tccacggttt cacatgtcct gaaaaatgga taatgtaagg attgttgcga gtttcttcgt
     7321 attcacgttc acctgctgct gttggatgtt tttttgcttt tgccatgata tagccttgtg
     7381 cattccaacg cggatgaagt ggtaaccaac ggtcatgtaa gatagcattt aatgcatctt
     7441 ggtcatggaa tcgtaatttt tctggattat gttcgatgaa atctaatact ttttgcgtaa
     7501 tattttcatc taaccatttt ttcacattga tcagcatcaa acctgagttg aaataacgca
     7561 ttgatttagc tgaaattttc attttttcca gtcgttgatg gaacccagcg tcttcaacag
     7621 ctgctacgat tgaatcaccg aagtcaagac gccataattt agagatatct tgtaaagcga
     7681 tcatgtcgca atccatatat aagatacgtt caacttctgt gccgcggaac aattccggaa
     7741 tcgcaatacg ataataagct gtttctggaa tacgatcgct gattaccaca tttgtaaaga
     7801 attctttatt gattttcaag aattccacat ctgagttcat tcgtgcgttt ttcactgaga
     7861 agcgtaaaag ctgtttactt tcaaaatcga tatcatcgtc aatcacatag aaccgaacaa
     7921 atttagacgg gttgcaatta tctaatactg agacaaataa tgcagctaaa tgtggtacga
     7981 attttgtgtt acaacttgcg actactgcta tttctttttt attcattgat ctcgcctact
     8041 ttcgttagag tactgtgtgc taattttttt aagtataaat tggtatacgg atgatctttc
     8101 aacgtattcc aaggtttatc atgtcctgta aagtgaacga tcgaaggttt ttcatttcct
     8161 tctttatact gacgttcata tttttcattt ggtgctggat gacgttcaaa aatcagcgaa
     8221 gtctgcatgt tccattttgg atgaagttgt tcccaatctt cataaagtac agcattcaaa
     8281 gcatcttggt cgtgatagat gattcgatcg ccattttcac tgaggtaatg gatagttttt
     8341 tctgtaattt cttttttatt ccattgatca atgtcaatca ccatcactcc tgaattgaag
     8401 tacaagtcat cggaatcgat tcctaatctt tccaaagctt tcacttggcc tggatcgata
     8461 atagcgccga ttgtttttcc atttaacggc tcatcatata gttttacgat atcgtctagt
     8521 actaacacat ctgaatctaa gtaaaggact ttcttataat cctctttagc taataagttt
     8581 ggtaaagaaa ttcttaagta agcggtagtt gtgatatggt cactgactag gaagtcttcg
     8641 tagatatctt tttccactgt caggaattgg atacttgcat tacttgaata tttatttacc
     8701 gtttcttcca atccttcttt actatattct gatagaccat cgtcaatcac ataaaatttt
     8761 atgcgtcttg ttttattgca attttctaat gcagttgcga tcatcacgct caagtaagga
     8821 gcataatttt cgtctgaagc agttaccaca ggaactacgc cgtatctctt ctccatcaaa
     8881 atcactcctt tttctaatct ttttctaacc tgttctacat ctagaatatt cctcatttgg
     8941 ttttaaagca aaatatatgc tttgttttca ttgaatattt taaaattttt ttatcacaaa
     9001 acgcatcggt aagcgctaac tattcgtttt tcatggcttt ttattcaaag gtattgacca
     9061 aaaactacta tatatagcca cctttttctt aagaatgttt tttgaaaaaa ttcataatga
     9121 caaagcaagt tagtttcatt tttttaaatt ctcatttaat cttaaggtaa caggaaaata
     9181 gatatgtaaa aagaaagtag gaagataaaa tgaaactagc agcgattgat ttagacggta
     9241 ccttgcttga tcgaaatgga aagataccag aagaaaatat ccaagcactt cggaaatttg
     9301 atgaaaatgg cggaatcgta accgtcgcta ccggaaggaa cagcatttct gctaaagata
     9361 ttttttccga attaggaatc ggtggctatt tgatttcttc caatggttca ctgattgctg
     9421 aaatgaagga tggaaaaatg gcgaaagttc tcagacgttc aaaaatagat agcgatacac
     9481 tgagaaaagc cttcttctat gctcaagaag cgaaaatatc catcattgct agccgagaaa
     9541 cccaagatga tcagctgaca ttcgatgaat caaatctagt caaagatgac ccttattatg
     9601 aacatttcaa tttacagaac cattcttttg atcaaatttt aaatatgttg gaagatcctt
     9661 ctcttagcta tcttaaatta gcattaacag ataagagtga agaaaaacta cagaagctac
     9721 aaagagatct gcaagcagat ggtatccaat cagtattctc tgatccgcat ttcttagaaa
     9781 tcacgcctac aggtatcact aaagctcatt cacttgtttt tctggcggat taccttggaa
     9841 tcgaatcgag tgacatcatg gcttttggcg atcaagaaaa cgacattgct atgttgaatt
     9901 acagcgggtt gagtattgcg atggggaatg cacagcgaca agtaaaagaa attgcaaacc
     9961 aagtaacact gacgaatgaa gaagctggtg ttgcttatat tttaaaaaac ttctattaaa
    10021 aagaataaaa tgacgatatg aatgtaggag gaaagaaaat gttagttatt attgatatgc
    10081 aaaatcatat tcttgatcca aacagcgaat tttatattcc agagtcagat caattggcag
    10141 aacgtattgc tcaaagatta gctaaagcac gccaaaataa tgaatatatt ctcttcacac
    10201 gggatatacc agttgaactg aaggacaaag aagaagaacg agaagatttg caattgatcc
    10261 ctcttctttc tccacaagaa aatgaacgag tgattaaaaa gtattacttt acgattccac
    10321 ctgaaacttt agctgaaatc caggaaactt tatttgaaag caaagaagaa caaaaagaga
    10381 tcgaagtagt cgggattgaa acaaacttgt gtgtactctc taatctgata ggcctgcaga
    10441 gtgcttttcc tgaagcagac ttttttgttg atccaatgtt agtctccagt agaaaacacg
    10501 gagaatccgc tttagagctg ttgaaagatt tcaacgtctc tatcgtcgaa tcataaaaat
    10561 atctatcttc atttacgata tttaacacac aataaaaaaa gcacgcagaa ctgttttagt
    10621 cctacgtgct ttttctatca aagtagattg gcttttttat gacacagagt gaaacggcag
    10681 gctcacgacc tctttcttaa atggtgttca atcagctgac cctcggtatt agcttaacaa
    10741 acggcaaaat atgaggaact atttttccgt ttgttaagct aatactcagg tcaaaacgct
    10801 gatttcacaa cctcttcctt aaacggtatt caaaagcttg catctgcagt aataagaaca
    10861 gccaagtaaa aacataagaa gctgttttta cttggctgtt cttattactt gatgcagggc
    10921 agctttttca caacctctta tgtaccttgt aggactcgaa cctacgaccg gacggttatg
    10981 agccgtctgc tctaaccaa
//
LOCUS       DACCVH010000092        10650 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.092, whole genome shotgun sequence.
ACCESSION   DACCVH010000092 DACCVH010000000
VERSION     DACCVH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.092"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            23..646
                     /locus_tag="IVV98_002451"
     CDS             23..646
                     /locus_tag="IVV98_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808047.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="IVV98_002452"
     CDS             1096..2145
                     /locus_tag="IVV98_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7808048.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="IVV98_002453"
     CDS             2142..3023
                     /locus_tag="IVV98_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808049.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="IVV98_002454"
     CDS             3026..3796
                     /locus_tag="IVV98_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808050.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="IVV98_002455"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="IVV98_002455"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP7808051.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="IVV98_002456"
     CDS             5107..6270
                     /locus_tag="IVV98_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP7808052.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="IVV98_002457"
     CDS             6387..6797
                     /locus_tag="IVV98_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7808053.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="IVV98_002458"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="IVV98_002458"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7808054.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9337..9654
                     /locus_tag="IVV98_002459"
     CDS             9337..9654
                     /locus_tag="IVV98_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808055.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9814..10050
                     /locus_tag="IVV98_002460"
     CDS             9814..10050
                     /locus_tag="IVV98_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7808056.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="IVV98_002461"
     CDS             10047..10445
                     /locus_tag="IVV98_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP7808057.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3717 a         1773 c         2253 g         2907 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat
//
LOCUS       DACCVH010000093         9949 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.093, whole genome shotgun sequence.
ACCESSION   DACCVH010000093 DACCVH010000000
VERSION     DACCVH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.093"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            194..1066
                     /locus_tag="IVV98_002462"
     CDS             194..1066
                     /locus_tag="IVV98_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7808058.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            1063..3021
                     /locus_tag="IVV98_002463"
     CDS             1063..3021
                     /locus_tag="IVV98_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7808059.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3353..4204)
                     /locus_tag="IVV98_002464"
     CDS             complement(3353..4204)
                     /locus_tag="IVV98_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7808060.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            4327..4794
                     /locus_tag="IVV98_002465"
     CDS             4327..4794
                     /locus_tag="IVV98_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP7808061.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(5057..5539)
                     /locus_tag="IVV98_002466"
     CDS             complement(5057..5539)
                     /locus_tag="IVV98_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7808062.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(5639..6502)
                     /locus_tag="IVV98_002467"
     CDS             complement(5639..6502)
                     /locus_tag="IVV98_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7808063.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            7100..7975
                     /locus_tag="IVV98_002468"
     CDS             7100..7975
                     /locus_tag="IVV98_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808064.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(8120..8272)
                     /locus_tag="IVV98_002469"
                     /pseudo
     CDS             complement(8120..8272)
                     /locus_tag="IVV98_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(8540..9871)
                     /locus_tag="IVV98_002470"
     CDS             complement(8540..9871)
                     /locus_tag="IVV98_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7808065.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
BASE COUNT         3141 a         1975 c         1721 g         3112 t
ORIGIN      
        1 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
       61 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
      121 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
      181 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
      241 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
      301 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
      361 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
      421 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
      481 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
      541 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
      601 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
      661 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
      721 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
      781 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
      841 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
      901 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
      961 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
     1021 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
     1081 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
     1141 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
     1201 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
     1261 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
     1321 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
     1381 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
     1441 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
     1501 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
     1561 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
     1621 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
     1681 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
     1741 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
     1801 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
     1861 gaaaacaaag caaaaacagc ttccttgatg ttagcagcag cttttgcttc attctttact
     1921 ggtgtaacag aaccacttga attctcattt atgttcgttg cttggccatt atatgtcttg
     1981 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
     2041 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
     2101 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
     2161 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
     2221 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
     2281 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
     2341 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
     2401 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
     2461 ttcgttgcag atgagatggc aaaactacat ggtggtgctg caacacgacc tgcacaaaca
     2521 aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga tcgaacaaga tatttacgct
     2581 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
     2641 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
     2701 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
     2761 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
     2821 ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
     2881 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
     2941 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
     3001 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
     3061 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
     3121 gccaactccg cggtaataag tccagccaaa cgtaacatat gaagagctat tttttatttg
     3181 actcttctta ttacttgatg cagaacagct tttttacaac ctctgataaa cggtgttcaa
     3241 aaaccagttt atcggtatga agtcaaattt atgcaaaaat gtggaaagcc attttcacaa
     3301 aatttttctt catactcaaa actaatcggc tttttcacaa cctctttata cattattcct
     3361 gatccaatat ttcttttaat gctgcttcaa gagaagttaa tggttttccc aatacttttt
     3421 ctaaatcatc agaggaaata gctaactgat cctttttaat atcatgttgg atcgctaaaa
     3481 acatgtcagc tgcttcttga gggaatccgg cttcttttag attttcgaca aacgctgcat
     3541 cacttgcttc aataatttct aactttttac ctgtcgcacg ctctaatgcc ttggctaatt
     3601 cttcatagtc agttagattg ccggataatt ctaagatttc tggagagtca ctttctacta
     3661 gtacttttgc tgcagcttct gcatattcac gtttcaatgc ccaacctgtt tttccatttc
     3721 ctgcagcata aacgaattga ccagttttta aagcctgccc aatgataggt aattcattct
     3781 ctacatacca attattccgt aaaaatgtat gggaaatacc tgaatcctta atcatttttt
     3841 cagtgaattg gtgatctggc gctaatacac tgatcgagtg atcggcatct gcaaaacttg
     3901 tataagcgat ataagatacc ccagctgctt gtgctgcctt cactacattc ttatgttcgg
     3961 cttgacgatt tcctggaacg ccagagacaa aaagcaatcg atctattcct ttcaacgctt
     4021 ctttcattga gtctaaatca tcataatcac caatacgtat attaaatcca gcttctttca
     4081 gtgcttctcc tttttcttca ctacgtacta gtacatagat ttcattttgt ggaaccatct
     4141 tttttaagaa ttccagcgca taaccaccaa aacctccagt tgctcctgtt actaaataat
     4201 gcatatttgc cactccctat tctttttatt tgttaagatt tacagctgta catttataaa
     4261 ttacaccttt atcataaaga gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga
     4321 caactgatga agtattctct gcaatttagt gatgcaatcc atgtacttgc ctatattgaa
     4381 atgtttcaag atacccgatc actttctagt gagatgattg ccagtagtat cgaaacaaat
     4441 gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa
     4501 accggaaaac cgcagccttc ccttgccaaa agtccagatc agatttcttt actagatgtc
     4561 tatcgcagca tcgaaggtaa tacacagctt atccaagtcg atccaaaaac aaatccaaat
     4621 tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa
     4681 aaggcagaag aagaaatggc taagatcaca cttgatagtc tgatacataa aatagccgtt
     4741 ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag agagattttt ataattctct
     4801 ctactgtgcc tgcatttttc tgatcggaat cgtctacata aattctttta ttctccgggg
     4861 gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct caggtcaaag cgctgaagtc
     4921 atgacgtctt gataaacggt gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc
     4981 aaaatatgga aagctatttc ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt
     5041 cacgacctct atattatcat ggtttattga ctaccggtat ccagatttct cccatatatt
     5101 tcccgttggt aactcccatt tcgactacag catttggacc cccaacatag gcgtaatctt
     5161 ctacttctct taaaacatgc ccaaaggccg tattcgtcaa atcatttctt aattcttcag
     5221 gcgattctgc taaagcgatt acaacaagat acgttccttt tgggaatggg atgattcggg
     5281 tagtgtttgg aacatcctga ctcgtttgaa caccgacata gtacatcatt ttcccgttat
     5341 agggttcgtt gactgtaaag aaataatgat tttcagcagc ttgtttcaat gcatctattg
     5401 ttccattacc gataactttt tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat
     5461 ccgtattgct actcttcaat tccacaccaa tacccgtcac cgtaaaatct ggtttttctt
     5521 cgatcctata ctttgccatt tctcccaccc tttctattat attaagttca tcttacataa
     5581 aattaaaggg aaatgacacg attacgctct tttttctagg gatattttta ttttttaact
     5641 atttttttgc tttcactgca atccaaatct cactgtaaac attactgaaa tcctctcccc
     5701 attttgtaaa agagatctcg ggagcttcga ctaactcata atctgaagaa ggaagccatt
     5761 ctgcatagat tttcccccaa gtatcttgta aagtttgggg aaatggccct ttattaggaa
     5821 aaatggccca agtgtgttct tctatagcaa gcatttctaa atcagcgtac ggattttctt
     5881 ttgtcgtagc aaagccaatc atgtgcatca aactgccctt ttcttccaag cgggctccat
     5941 caaatccata agaaacgttg attacttgat ttggatataa atctcctaac ttatgcatct
     6001 cttccctttg agtctccgtg atcgtctgcg ctaacttttg tatttcttga ttgactcctt
     6061 caaatttgac aggaactttt ttcgccacac ctgccacata aaactgttct ttcttttcga
     6121 tacgaaattc catcgatttt cctcctctga catcaataaa aaatgtcaag cgtggaaaag
     6181 atttttgtat gccgtatctg ctgatttctg aaggcagata tcctgaccaa tcacgaaaag
     6241 ctcttgaaaa accttcgact gtttcatatc catatctaaa cgccgtttct gtcactcttg
     6301 atccatctag gagatcgcga ttagccaaag ccaatctacg gtttttgata tagtccatta
     6361 gcgacatccc tgcaataaac gtaaagatgc gttttaattg atattcagag attcctgtat
     6421 tttcggctat tattttatag gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca
     6481 attggttcag atctttaagc atatttatct tcctccttgc ttgccttttt atcatattat
     6541 caaagaaagt caattacttg atgaatcagg aaccaattta gtcagatgta gaaaatgttg
     6601 tatggatcta aagaaaattc tcaagcagcg tttcgtaacg gataattggt attatctgcc
     6661 tatctatgtt ttacctttag aaaaataaat tttggggaag acacattcta agtaaacaaa
     6721 gcggtaaaaa tatcttttat tcccttagtt aatccgctta ctacctactg tacaaagcaa
     6781 attgttgttc aaactgctga tcagaacgct gcttggattt ttctttgcga tacatcatac
     6841 ctcttttatc aattggaaca attatttatt tctaacaaaa tcacttcatt tttgtcagat
     6901 aaataaaaaa caaaaaaagt tccatcttta aaacacgcta ttcttttact ttttctcaca
     6961 ttctctaaga aaagaaaagg agaatgaatt tttgacaatt cgagcaaaag tgattatcaa
     7021 atatgtaaaa tcagctactt ttttcttaaa cgtttcttta tactaaatat aaataagtgt
     7081 ttcatgaaag gagaactaga tgaataattg gcttgagtat tttcctgaaa acgttttgga
     7141 acgcggttac agctatcatc tgcacggttt tgtccgtcat ttgaactata caagcaagta
     7201 cttgtccgca acagtttctg gcacggaaga ttataaggta gtgatcactt gggatgaaaa
     7261 gaccaacatg acttgtgatt gtctatatgc catagaagga aaaaaatgca aacacatggc
     7321 tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa tccaactact cactttccga
     7381 actctcgtcc cttgtttcct ccgctagttc ctctcttgta cgggagcttt taacagagat
     7441 tcttatagaa catccgcaat ttatcgaacg cttcaaagtt aagatgccat ttcatgcaat
     7501 aaattattca gataaattaa caactatcat ccataaatac gatcatatta tcaagaaaaa
     7561 caaaaacagg aaaacagcga agttcatcat ggagatgcga aagttcatcc aagaagcagt
     7621 tgaatcgctc attcagcaaa atgcctatct tcccgcattc gaattgatca atgaagtgat
     7681 tgctactctc gaaacattct attgggagcc tgaggatgaa cgaacccttc ttctgataga
     7741 ggactgttat tatttatgga aagaattatt agcagaagca cctcatgcag aaaaaaggca
     7801 aatgttctct tggttcgtct gccaagtcga tcatactgac gcctcttatt caaaacgcta
     7861 ctccataaaa atcctgaaag aagactttcg ggaaaaagaa ttttctaacc aaaagaaaaa
     7921 aatagataaa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
     7981 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
     8041 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
     8101 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct gggtagattt
     8161 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccactg
     8221 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac cactctaatc
     8281 tttaaagata aatattaaaa taacgattaa taatattaac agtctttatt tttcaccacc
     8341 aaaaacctat ctttgcatat actaaataga cgtatataca cagataggtt tgtcttgtga
     8401 aaaataatga ttatccttac caaaaaatgt ttgtttttct acatgttcgt acttatcaaa
     8461 aaatatgatc cttattgaaa ttactggcta tttatattcc aacgacttct tgtgttaatt
     8521 tttgttatct catagtaaat tatgtttcat tttcacttaa tttagttgtc acgtgttcgt
     8581 caattcgtaa aaacggtaaa tatataaaca cacttgcggc tataattaat atttgtaaaa
     8641 cagctgctcg ccagtctccg gctgttgcta aaaatcccga tataactggt ggcgtagtcc
     8701 aaggaatttg cactactaca tgattaatta atcccacagc agttgcaaaa tatgctactg
     8761 tcaaagaaaa aatcggtgca agcacaaagg gaataatcag actgatatta aatacaatag
     8821 gcaatccaaa aataataggt tcgcttatat tgaatatagc gggagttacc gataatttag
     8881 caaagtcctt ataatctttt ctacgactga agataaatat tgcaatcaat aaagcaatcg
     8941 tatttcccga tccacccatt accgcaaagg tatctttaaa ggccatattg ataatatgtg
     9001 gaatttgctc tttgtttgca taagctgcca tattttcttg catattctga atcaaaaacg
     9061 gatctaacaa tgaacctgat attactgctt gatggatacc aaatccaaaa aatagattag
     9121 caatagatgt aattaacaaa aatcctggta aaccagttgt aattttactt aatggctctg
     9181 taactatcgt ggtaattagc ttatttatat ccatattaaa caattgaatg attataaatg
     9241 acaataaagc aaacgaggta atcgtaataa tgattgggat taatacatta aaagacttta
     9301 aaacagcggg aggaatattt ccggatagct gaatctgtag tttcttatta ttagaaagtt
     9361 taataaataa ttctgtagcc gctaatccaa caaatatacc tacaaacatt cctgaagctc
     9421 ctgtatagga tataggtatc acacccgtca cttcaacagc tttatccgca ttttcaggag
     9481 taaacatcat ctgcataggt gttaatacaa caaatgtcga aatagcaact aataccgctg
     9541 caatatgatt tgtataattt ctgcttgcac acatatgata agatactgct gctacaacta
     9601 ataatgtagt tatgcttaat gtaccattgg caattgaagt accaatttgt tgtaacgtgg
     9661 tcaatgtact agtatcgaca atttccccca tgaatcctgt tggttctaag atcactgaat
     9721 taataagtgt cacaaatcct gctaacatca taaatggcat aaatgtagca aacgcatctc
     9781 gcaaagttct taaatggatc tgattcccca acttagtcgc aactatacca aatttttcaa
     9841 atacaatgtc cttcctgcta cttttgccca tattttttct cctttatgct tattgtaatc
     9901 gattactttt tccacccaaa taatacatca cttatcaaaa aaagtaaat
//
LOCUS       DACCVH010000094         9945 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.094, whole genome shotgun sequence.
ACCESSION   DACCVH010000094 DACCVH010000000
VERSION     DACCVH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.094"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            32..388
                     /locus_tag="IVV98_002471"
     CDS             32..388
                     /locus_tag="IVV98_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808066.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="IVV98_002472"
     CDS             404..754
                     /locus_tag="IVV98_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HAP7808067.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="IVV98_002473"
     CDS             783..1562
                     /locus_tag="IVV98_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HAP7808068.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="IVV98_002474"
     CDS             1573..2235
                     /locus_tag="IVV98_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HAP7808069.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="IVV98_002475"
     CDS             2254..3360
                     /locus_tag="IVV98_002475"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HAP7808070.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="IVV98_002476"
     CDS             3350..4441
                     /locus_tag="IVV98_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HAP7808071.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..5194
                     /locus_tag="IVV98_002477"
     CDS             4454..5194
                     /locus_tag="IVV98_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HAP7808072.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            5482..7422
                     /locus_tag="IVV98_002478"
     CDS             5482..7422
                     /locus_tag="IVV98_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP7808073.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            7509..9431
                     /locus_tag="IVV98_002479"
     CDS             7509..9431
                     /locus_tag="IVV98_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAP7808074.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(9711..>9945)
                     /locus_tag="IVV98_002480"
     CDS             complement(9711..>9945)
                     /locus_tag="IVV98_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP7808075.1"
                     /translation="DLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPAQ
                     AVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         3248 a         1651 c         2207 g         2839 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atggtaaaaa aaattattca ctaactcatt agaaaataag aagcttattc
     5221 cagaatgaaa ttaaatggaa taagcttttt ataattaatt acggaaattg ttaatgtaga
     5281 taataattta gatgtacgta agcagaagta cagaaatgta agattttcca atattatttt
     5341 attcaacata ataaatcgta tatcaatttt tttagcgaaa tttctattta ttccaagaat
     5401 ttcagttatt acggaatcat tttgtgctta ataaaaagaa accgttttta tatactataa
     5461 atgtagaaag gcggtaggaa aatgaaaaaa attattgcaa tcacatcctg tccagttggt
     5521 attgcccata catacatggc agcagaaaac ttagagaaag cggggaaagc agttggcgcc
     5581 gaggtaaaag tcgaaacaca tggttccatc ggtattgaaa atgaattgac tgcaagagat
     5641 atcgaagaag cagctggtgt aatcatcgca gcagatacta aaatagataa atcacgattc
     5701 ggcggtaaac ctttgataac cgtaggtgtg caagaaggaa tccaccatgc agatgagttg
     5761 gtgagagata ttttagcagg aaaagcgcca gtctataaaa gtacggaggc aattatttct
     5821 tccgaaaata aaagtgaatc agaaaattta ggtaaaaaaa tctataagag tttgatgaat
     5881 ggcgtttcgt acatggtacc tttcgtagtt acaggagggt tattgatcgc gatttcttta
     5941 acattaggag gaacagctac acctgaaggg atcaagatac cagaaggaac gatttgggca
     6001 acgatgaata gtatcggaag tatcgctatg gggttgatgg ttccaattct atctgcattt
     6061 attgcgcaaa gtattgcaga tcgtccagga cttgttcctg gatttgttgg tgggatgtta
     6121 gcggcaaacg gagcattata tggtagtgat gcgaatgcgg gattcttagg cgggatcatc
     6181 actggatttt tagcaggatt cattgcttta ggaatcaaga aagtgcgagt accgaaagct
     6241 ttacaatcga tcatgccaat tattgttatc ccaattttag gatcattggc agttggtttt
     6301 gtgtttatct atgttattgg agaaccagta gctcttctat ttagttcatt gactcacttt
     6361 ttagcaggga tgcaaggagg aagtgaaatt gttctagcta tgatcttagg agcgatgatt
     6421 gcttttgata tgggggggcc gttcaataaa gtagcctttt tgttcggatc tggcttgatt
     6481 gcagaaggca attattccat tatggggcca attgctgtag ctatctgtat ccctccatta
     6541 gcattggggc tggcatcatt gattttaaaa accaaattta cgaaaacaga acgagaagct
     6601 ggtaaggcgt ccttagcaat gggactgttt gggattacag aaggcgctat tccgtttgct
     6661 tcaacagatc cactacgggt gattccaagc attgtaatcg gggcaatgac aggaagtgtg
     6721 atcgcgatgc tttcaggagt gacagatcat gtagctcatg gcggtccgat cgtagcggtt
     6781 ttaggagcag tggatcacgt agccatgttt tttgtagcag tgattgctgg tattgctgta
     6841 accgtgctaa tgttaagaat ccttaaaccg acattacaac aaactgcggt tgctgcagca
     6901 aatggtgtga cagtagcaga tctatcagag actgaaacaa gtgatgttta tacgaaaact
     6961 gaaacttttg attctatcac ggatattatg tcagatgaag caatcgtttt aggtgaaaca
     7021 gcaacaacaa aagacggagt aatcgaagat ttagtccaac gtttagaaaa aacagcggcg
     7081 atcacagata aaaccagatt taaagaagtc atctatgata gagaacatga aagtacaacg
     7141 ggaatcggta tggggattgc tattccacat ggaaaatcag cttatgttct taaaccaaca
     7201 gtggcatttg ccagaagtca atctggggta gattggcatt ctttagatgg aaaacctgca
     7261 catatgatct ttatgattgc tgtacctgaa aacagccaag gtgatatgca cttgaaaata
     7321 ctgcaacgtc tatcacgtaa attgatggat gatgacttcc gtcaagcact gatggaagcg
     7381 ccagataaaa caacagttca ccaattatta agcgaaatgt aacataagat gaaaaatcga
     7441 ccgtgatgag acataataga tgtgttatca tgatcgattt tttatttaga agggagtttc
     7501 tgcacattat gaatcagcgt cagcaatctt tgatctatca attaagtgag aacaataatt
     7561 atataacaac aaaaaagcta gcagagcatt tccatgtgtc agaaagaacg attcatagcg
     7621 atttgaatac cattgaaact tggttgagag acaaacatct gcctttaatg tttgaaagaa
     7681 aaaaaggtac aggtatcttg ttgaatggtc tgcctcacga aagggaacaa ctgaaacgag
     7741 cgcttaatga agagactcaa acagaaatgg ataaaaaaca gcttcgtcag ttattgattt
     7801 tccatctgct agtagcaaaa gacggattta gtcttgaaga actttcagaa aaactatatg
     7861 ttggaaaacg tacgattcgt aaagaattga cagagttgca aagctttttt gagtatcacc
     7921 atttacagct agtatccaaa acaaaactag gaacttttct taaaggcgat gaacaagaaa
     7981 aaagacagtt gcttgttaag acattacgaa atatgcagaa agaagatcca caaagtccgt
     8041 cgttgaaaga attcttcgct aaagatacat taaaagttat ccaacataca ttacaagatg
     8101 ttttttatga aaaccattta gaacagccga atggactggc tagtgtggag attcacatct
     8161 actttatgct cgagcgaatg aaacagtacc agaaagtgaa attaagtaaa gacgaaaacg
     8221 aagtcgtgga acacacccaa gcacaaaagt taagtagtca aatattagca aaactagcca
     8281 ccatctatcc aattgaattt tctcctgatg aaatcaatta tctggctttg cgtatcgcca
     8341 atctttttac aaattcacaa gcagccacac gttttcaaaa ggaatctagc gcacttgctg
     8401 atcatttgat cgaacaagtg gaacagtttc taggctattc attaaaagaa gatcagctac
     8461 taaaacaaaa tttaaggtct catttatctt caacttattt tcgactccat tatggtttgc
     8521 agatttctaa tccattgacg aaaaatgtgt ttagtacgta cacacaactt ttcttagttt
     8581 tacagttaat tttagaagat tattttgaaa aggaaaattt ttatgttcca caagaggaga
     8641 cagcttattt aacgatccat ttccaagcag cgatcgagcg acacaaacat cagaaaagta
     8701 gaagatatca aacggtttta gttagtgaat attcaaaagc tatggctact tttctcgaag
     8761 cacggctgaa cagagaactt ccagaattaa cgattatgga tctagttgaa tataagccag
     8821 aattaaagag acaagatttt ccctctgttg attttatctt ggctacgtta ccatttaaac
     8881 atataagcat tccagtaatc gagatctcac caatgatcac agaaactgat ctagcctatt
     8941 tgacaaaata tatgctggag catgtgccta tcaagaagaa aaaaacattt gatctagcaa
     9001 gctttactca tccatttctg atctttcctc aacttgaacg gacagaccca gccgatattt
     9061 taaactttat gggaaacgtc ttagtggaac atcattatgt ggagccggaa ttcatcgatt
     9121 ctgtcttgga aagagacagt cactccagta ctagagtagc accatttgta acaatccctc
     9181 acggtaatcc gctgtatgtg aagcattcga tgatttctat tgctacaatg aaagaaccag
     9241 tcctatggca cggggaacag atacgtatcg tactgctatt agcaataaag aaaaatgatt
     9301 tgaaacatgc agagttcaaa aaaatatttt ctgttattca ctatctagaa aagcagccag
     9361 aacaaatggc tcagttgatg caatccaatc atccgctaga aatcttaacg ttgttatcta
     9421 gttatgaata agtagcgatt aaaaaactgc ctttatattt ataataattc tatctattta
     9481 tttggaagta gaaaactaaa tacaaaaaaa gaggatgtgg ccaaagttgt ggcacatcct
     9541 tttattttga gtttcttata attttttata gttgcttacg atgtcttgac tactggtaaa
     9601 cggtgttcaa gagacaattt gtcggcaata aggcacaatt ttgtaaaata tggaaagcta
     9661 tttttttaac attgtttctt agtgcttgaa aaatcatttt gaatacttct ttatacgatc
     9721 gatgtacgtt gatttaagtc taaaactttt cttttgattc cttctctgac ttttctgaat
     9781 tccgttaata tttcttcttc gctcccgaca gcttgtgcag gatcttttag gtcccagtga
     9841 aggtgttcgt gattgtttgg aacggcaggg cacttgtctt tggcatcacc acaaagtgta
     9901 atgatcaagt ctgcctgagt aaagtaatct ctatcaatca aatca
//
LOCUS       DACCVH010000095         9888 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.095, whole genome shotgun sequence.
ACCESSION   DACCVH010000095 DACCVH010000000
VERSION     DACCVH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.095"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(109..2229)
                     /locus_tag="IVV98_002481"
     CDS             complement(109..2229)
                     /locus_tag="IVV98_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7808076.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="IVV98_002482"
     CDS             2459..3637
                     /locus_tag="IVV98_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP7808077.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="IVV98_002483"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="IVV98_002483"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP7808078.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="IVV98_002484"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="IVV98_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP7808079.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="IVV98_002485"
     CDS             complement(4990..6243)
                     /locus_tag="IVV98_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7808080.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="IVV98_002486"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="IVV98_002486"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP7808081.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="IVV98_002487"
     CDS             7821..9167
                     /locus_tag="IVV98_002487"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP7808082.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="IVV98_002488"
     CDS             complement(9475..9861)
                     /locus_tag="IVV98_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7808083.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3150 a         1800 c         2024 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DACCVH010000096         9688 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.096, whole genome shotgun sequence.
ACCESSION   DACCVH010000096 DACCVH010000000
VERSION     DACCVH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.096"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            34..771
                     /locus_tag="IVV98_002489"
     CDS             34..771
                     /locus_tag="IVV98_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7808084.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            785..1600
                     /locus_tag="IVV98_002490"
     CDS             785..1600
                     /locus_tag="IVV98_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP7808085.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1613..2260
                     /locus_tag="IVV98_002491"
     CDS             1613..2260
                     /locus_tag="IVV98_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7808086.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2276..2932
                     /locus_tag="IVV98_002492"
     CDS             2276..2932
                     /locus_tag="IVV98_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7808087.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3094..3915
                     /gene="racE"
                     /locus_tag="IVV98_002493"
     CDS             3094..3915
                     /gene="racE"
                     /locus_tag="IVV98_002493"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP7808088.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3918..5273
                     /gene="rph"
                     /locus_tag="IVV98_002494"
     CDS             3918..5273
                     /gene="rph"
                     /locus_tag="IVV98_002494"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP7808089.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5274..5792
                     /locus_tag="IVV98_002495"
     CDS             5274..5792
                     /locus_tag="IVV98_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP7808090.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5899..6399
                     /locus_tag="IVV98_002496"
     CDS             5899..6399
                     /locus_tag="IVV98_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7808091.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6679..7599)
                     /locus_tag="IVV98_002497"
     CDS             complement(6679..7599)
                     /locus_tag="IVV98_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP7808092.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7764..8777
                     /locus_tag="IVV98_002498"
     CDS             7764..8777
                     /locus_tag="IVV98_002498"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP7808093.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(8887..9642)
                     /gene="fabI"
                     /locus_tag="IVV98_002499"
     CDS             complement(8887..9642)
                     /gene="fabI"
                     /locus_tag="IVV98_002499"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP7808094.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         3136 a         1701 c         2082 g         2769 t
ORIGIN      
        1 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
       61 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
      121 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
      181 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
      241 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
      301 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
      361 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
      421 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
      481 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
      541 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
      601 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
      661 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
      721 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
      781 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
      841 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
      901 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
      961 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
     1021 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
     1081 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
     1141 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
     1201 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
     1261 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
     1321 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
     1381 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
     1441 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
     1501 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
     1561 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
     1621 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
     1681 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
     1741 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
     1801 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
     1861 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
     1921 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
     1981 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
     2041 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
     2101 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
     2161 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
     2221 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
     2281 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
     2341 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
     2401 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
     2461 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
     2521 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
     2581 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
     2641 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
     2701 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
     2761 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
     2821 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
     2881 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
     2941 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
     3001 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
     3061 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
     3121 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
     3181 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
     3241 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
     3301 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
     3361 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
     3421 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
     3481 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
     3541 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
     3601 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
     3661 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
     3721 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
     3781 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
     3841 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
     3901 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
     3961 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
     4021 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
     4081 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
     4141 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
     4201 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
     4261 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
     4321 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
     4381 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
     4441 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
     4501 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
     4561 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
     4621 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
     4681 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
     4741 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
     4801 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
     4861 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
     4921 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
     4981 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
     5041 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
     5101 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
     5161 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
     5221 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
     5281 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
     5341 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
     5401 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
     5461 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
     5521 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
     5581 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
     5641 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
     5701 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
     5761 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
     5821 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
     5881 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
     5941 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
     6001 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
     6061 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
     6121 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
     6181 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
     6241 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
     6301 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
     6361 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
     6421 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
     6481 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
     6541 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
     6601 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
     6661 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
     6721 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
     6781 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
     6841 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
     6901 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
     6961 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
     7021 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
     7081 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
     7141 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
     7201 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
     7261 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
     7321 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
     7381 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
     7441 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
     7501 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
     7561 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
     7621 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
     7681 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
     7741 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
     7801 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
     7861 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
     7921 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
     7981 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
     8041 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
     8101 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
     8161 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
     8221 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
     8281 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
     8341 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
     8401 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
     8461 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
     8521 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
     8581 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
     8641 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
     8701 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
     8761 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
     8821 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
     8881 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
     8941 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
     9001 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
     9061 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
     9121 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
     9181 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
     9241 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
     9301 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
     9361 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
     9421 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
     9481 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
     9541 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
     9601 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
     9661 ctgataaaaa tttgatagtc gtaaaaaa
//
LOCUS       DACCVH010000097         9533 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.097, whole genome shotgun sequence.
ACCESSION   DACCVH010000097 DACCVH010000000
VERSION     DACCVH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.097"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(130..777)
                     /locus_tag="IVV98_002500"
     CDS             complement(130..777)
                     /locus_tag="IVV98_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAP7808095.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="IVV98_002501"
     CDS             complement(1056..1559)
                     /locus_tag="IVV98_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7808096.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="IVV98_002502"
     CDS             complement(1682..2446)
                     /locus_tag="IVV98_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP7808097.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="IVV98_002503"
     CDS             2553..2828
                     /locus_tag="IVV98_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP7808098.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="IVV98_002504"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="IVV98_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP7808099.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="IVV98_002505"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="IVV98_002505"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP7808100.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="IVV98_002506"
     CDS             complement(5605..6063)
                     /locus_tag="IVV98_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP7808101.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="IVV98_002507"
     CDS             complement(6060..7523)
                     /locus_tag="IVV98_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7808102.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="IVV98_002508"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="IVV98_002508"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP7808103.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="IVV98_002509"
     CDS             8598..9347
                     /locus_tag="IVV98_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7808104.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2856 a         2007 c         1643 g         3027 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat ctataaagtt actttaaata acaaaaaaat
     9481 aattgaaaat acttaaaatc aaaaaatatc tttttaatca ataaaaaaat tga
//
LOCUS       DACCVH010000098         9321 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.098, whole genome shotgun sequence.
ACCESSION   DACCVH010000098 DACCVH010000000
VERSION     DACCVH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.098"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..107
                     /locus_tag="IVV98_002510"
     CDS             <1..107
                     /locus_tag="IVV98_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HAP7808105.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="IVV98_002511"
     CDS             complement(176..904)
                     /locus_tag="IVV98_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7808106.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="IVV98_002512"
     CDS             complement(917..2197)
                     /locus_tag="IVV98_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7808107.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="IVV98_002513"
     CDS             complement(2338..2940)
                     /locus_tag="IVV98_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP7808108.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="IVV98_002514"
     CDS             3185..3391
                     /locus_tag="IVV98_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808109.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="IVV98_002515"
     CDS             3703..4422
                     /locus_tag="IVV98_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7808110.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="IVV98_002516"
     CDS             complement(4503..5186)
                     /locus_tag="IVV98_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP7808111.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5404..7590
                     /locus_tag="IVV98_002517"
     CDS             5404..7590
                     /locus_tag="IVV98_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP7808112.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7936..8346
                     /locus_tag="IVV98_002518"
     CDS             7936..8346
                     /locus_tag="IVV98_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP7808113.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            8360..8716
                     /locus_tag="IVV98_002519"
     CDS             8360..8716
                     /locus_tag="IVV98_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP7808114.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3362 a         1526 c         1745 g         2688 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa ggaaaaattt tcagaaaact aaaatcatat
     5281 cgcttcccat tttcattttt agaaaggtct gttagtataa agaaaaaata gacaacgaaa
     5341 ctttaaataa ccaacttgaa ataaacaaat tcaaagaaga aagatgggaa ggaaatcaat
     5401 cagttgaatg aaaaagaaat tctccgatta caaaaagaat tgaaacgctg ggagaacaag
     5461 tataaaaagc ttcaacaagt ctttcggcta caagaagaaa tcattgctac ctatgaagcg
     5521 gcttatggcg aagcacccgg acttattgag gaagaagtac aagtaaaaga aagtgaagga
     5581 aacagctctt tctttaaaat gatggagaaa cgttcctata atcgcttcaa tcaagaacaa
     5641 aaagcagcta tcacatatga tatgaagaaa catcttcgaa tcatagcagg agctgggagc
     5701 ggcaaaacgc aaacaatctg tgcaaaagct gtttatctga tgacgcaaaa acaagtagac
     5761 gaagaacgca tactaatgat cacttttaca aggaacgctg caaatgaact aaaaaaacga
     5821 gtagataatt tcagccagag aaaaaccgct gtccatatcg gaacattcca tagtatcttt
     5881 tttaggatat acaatgaaat ttgtcgaaaa tttcctgaag tagcaatgca aggaatacaa
     5941 ggagactttt caaaggatac tgcacaaaaa gtgaatgctg ttttgcaaca gctgatacgt
     6001 aaatataatc tttatatatt tgatcaatat ggagaaaaaa cgattgcttc tcggttagac
     6061 tattggcaga atatgaacct ttcagtagaa gaaatggttc agttagttaa agaaaaatat
     6121 gattccattg ataagaatgc acgacagccg atatcagaac gactgtatgg attgctcacg
     6181 gaactccaag aacaaaaaag aagccagcaa ttgctagagt tcaatgatgt actccaaaat
     6241 ctgaaaagcg ctttggagaa tgaggagatc cagcattata tcggccaaaa atatgattat
     6301 ctattcattg atgaatttca agatactaat ccacttcaat gggaaatcgt gaaacggatg
     6361 acaaaggaaa acaggatcaa gttgattgtt gttggagatg atgatcagag tatctatgga
     6421 ttcagaggat cagagccagc atacatcaag aactttgaaa aagaatatcc taccaaaact
     6481 cttttcttat taactaatta tcgttctcgg gcagctattg tccaaggagc aaatagattg
     6541 atcagctata ataaaaatga tcggatacca aaggcgatga ttccagcaca aaaagaagca
     6601 ggtgttatgg aagcctattt gttttctgat actaaagcag aaagtcagtg gctaatcaaa
     6661 caaattcaga catttattca aaaaaatggg aaatataagg aatcaatcat attataccga
     6721 tcagcttcac aaacgcagca gcttgtccaa tctctgctga aaacgaatat tccttttgta
     6781 ctggaagcag atagtccata tgaaggtatc tttggtatca agtctttcca acatttctat
     6841 caaaaaattg ttcattggca aacagcactg aatctgcaaa agaaaaatca ggcctaccag
     6901 caattgctcc ggcagctgat ggcagactgc tacctgaaaa aaagtgaatg cgatcaatac
     6961 ttttctccta aatatcaaaa tatagccgtt gcagattata ttttgtcgat aagccccaat
     7021 ttaaaatcga aatctgcaga aatccgagag tttgaggaag cgttgcgtaa aacagaccag
     7081 catcaagaaa tctattcgct tgttcaaagc tatcttcatc tgccacgtat agctaaggaa
     7141 atcgaccaga gtgatcaaga atggatacga gaagaagtaa agcagcatgc tactttcaga
     7201 agactccaag ccttatcgca agaaacccaa gcgacagcta aagaattaaa aacccgcttg
     7261 attgcttaca gacaaggaaa acttgatgca ctatgtatcc agagcattca caaaagtaaa
     7321 ggtcttagtt accgaaatgt ctttttgatt ggttgtaacg aaggaagttt gccttataac
     7381 ggagcgacag aaaagaaagt aatcgacttt aatgaaataa aagcagaacc agtaacgacg
     7441 atagaagaag aacgaagact attttatgtt gcgatgacta gagcaagaaa tcgtctgtat
     7501 ctatgtgtac ctcaaatgaa aaattcaaga aaattgaaag tatcgagatt tatcaaagaa
     7561 accgggagtc gtgtgaaaaa aggaaagtga tagaagagag ggtgtgacag aagtggtcag
     7621 tttcaagaaa gaagaaggaa tgtacgaaaa ttgcttctca aatttttgtg aaatttcagc
     7681 ttattttcga agaagctatt tctggaacac agtttattcg gaaaagggag gtgtgacaag
     7741 aattttgtca cacctccctt atttattttg aaaatgagaa tactattatc aaaatagaga
     7801 atatatagaa aaattctcat tattcaaacg taaataatca gttattttga ttttttttat
     7861 attttattag ctaataattg gtattttaaa agaaattact gtagaattgg attataatta
     7921 aaaaggagtg agaaaatgat aaaagtatat acttcgccta gctgtacttc ctgtagaaaa
     7981 gcaagagcat ggttgcaagc gaatcaactt gaatttgaag agaagaatat ttttgccgaa
     8041 ccgttaacag aaagtgagat caaaaagatc ttggcagcga ctgaaggagg agttcaagat
     8101 attatttcca ctcggtcgaa aatttacgaa aagctgggca tagattttaa cgaattaact
     8161 ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat tattgagacg acctattttg
     8221 attgatgaaa aaagaatact aatcggattt aatgaagatg agatccggtc atttgtccct
     8281 cgtgaaattc gatgtgttgc cagaaatctg atctatttac aaaacaataa catcttaaat
     8341 tcatagggag ggagccttcg tggaagtgaa agtctatgga tcagcgcact gtgtaacaag
     8401 tctgaaggcg aaacaatggt tagaacacca tcaattgcct tatcaatttg ttgacttaga
     8461 agaacgcgat ttaagtacag aagaagcaga agaattatgc agttttgaag aagtgcaagc
     8521 agaacagcta tttgcgactt ggtctgaggc ttttcacaac attgcgattg acctttcctg
     8581 tgtaggaaaa aaacaactga tttttttatg cacacaacat accaatctcc tcagacgtcc
     8641 tttgattatt atcgatgaag ttctatttat tggatacaat gagcagttga tggaacagct
     8701 tatcttaaat aaatagactt taactgtttt aatcaagtca ctgagcattt catacagttg
     8761 taacagtcga acacttagca tcaagcgtgt tatgtgttct ttttttgact ttatttttct
     8821 actatagaga catgctcaat ttatgtggtc aaaattcaaa tctaggtggg gatatagagt
     8881 taaaaatata ttgacatgtg taaatttaca tgatatattc atttctgttg ttttaagtag
     8941 caaagcaata aaatagtatt ttaaaaaaca tataaaatag ttgttgacat gttagaaatg
     9001 acatgataag ataactgagt tgttaaaaaa gaaccacttg tgaagcttga ttctatcgaa
     9061 aaaaacttca aaaaagttct tgacaaataa caaatgataa gttatgataa atgagttgct
     9121 gtaagatttc gaaaaacgaa atcaaaaaaa cttttaaaaa agagttgaca attacttgtc
     9181 tctctgatat gatataaaag ttgctacggc agccaaaaac gaatcgggga acactcctga
     9241 tgaagtagac ctttgaaaac tgaacaaagt aagacaaacc aaatgtgtag ggcgtcttga
     9301 ttcaattcaa gacaacaaac a
//
LOCUS       DACCVH010000099         9308 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.099, whole genome shotgun sequence.
ACCESSION   DACCVH010000099 DACCVH010000000
VERSION     DACCVH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.099"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(39..707)
                     /locus_tag="IVV98_002520"
     CDS             complement(39..707)
                     /locus_tag="IVV98_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7808115.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            841..1128
                     /locus_tag="IVV98_002521"
     CDS             841..1128
                     /locus_tag="IVV98_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808116.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1544..3082
                     /locus_tag="IVV98_002522"
     CDS             1544..3082
                     /locus_tag="IVV98_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP7808117.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3079..4044
                     /locus_tag="IVV98_002523"
     CDS             3079..4044
                     /locus_tag="IVV98_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808118.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4031..5353
                     /locus_tag="IVV98_002524"
     CDS             4031..5353
                     /locus_tag="IVV98_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7808119.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5416..5520
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5594..6337
                     /locus_tag="IVV98_002525"
     CDS             5594..6337
                     /locus_tag="IVV98_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808120.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6352..7344
                     /locus_tag="IVV98_002526"
     CDS             6352..7344
                     /locus_tag="IVV98_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7808121.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7356..8093
                     /locus_tag="IVV98_002527"
     CDS             7356..8093
                     /locus_tag="IVV98_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808122.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8083..8805
                     /locus_tag="IVV98_002528"
     CDS             8083..8805
                     /locus_tag="IVV98_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP7808123.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8889..>9308)
                     /locus_tag="IVV98_002529"
     CDS             complement(8889..>9308)
                     /locus_tag="IVV98_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP7808124.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3049 a         1604 c         1966 g         2689 t
ORIGIN      
        1 tatttctgta aattaaataa agtagtgaaa aataagaatc agtgctctaa ctgttcaaga
       61 ggatcaagtg gttcaaatgt ttctgtagtc tgttttgctt ccaattgggg caaaacagat
      121 ccaatttcca gatacttcac tttattcaat gtataagata gaatagaaca gctaagtaat
      181 gtatacagaa aatgtgtgag atccaaataa agcaaggaga caactaaaat accaaaagta
      241 atcaagaaaa gacttttgcc aatcttaata tgaaaatatt tttcaatggc ttgataaatg
      301 atatctgttc cgcctgtgct tccgccgaat cgaaagacga gaccgcaacc aatgccagaa
      361 agaatacctg tcatcaaact attgatcagt agactatcta cagcaaaatg tatatgaagg
      421 ctctcccata aatgtaaaaa gaaaactagc gcaaatgttc cgacgatcgt ccggagaaaa
      481 gcgtgttttc caaaaagaaa caatgagata agcaataaag gtaaattaaa aagcagtgaa
      541 gtgacagaag gagcgaatcc aaaaagatta tgcaaaagca aagcaatacc agtaacccca
      601 ccatctgcca gcttagatgg aatattgatt cctgtcacag ctaatccgta gattcctgcg
      661 cctaaaatga ttccgcacaa ttctgtaaat aaatttaatt ttttcatttc tagcctcttt
      721 tcttttgaaa attttcagca acttctttat tatactgact tatactctta cttcaagagg
      781 aaaatgaaaa aaaattattt ttggctgttt ctttttattt atcaaataag gagtggaaaa
      841 atgcgagcag cagacttatt gacaattctt acaaaatcac ccaaaaaaac agagtatcaa
      901 ggagtttttt tggctcaaga acaaaaactg gtgcctgtga caatggtcca gataaataaa
      961 gcaaatcaat ttatcttttt atttgaacac ggcaaagcac cacttgctat gaaagacatc
     1021 tttctttttt tgatgaagaa ccgtgagaaa gctgtttatt atcagtcaaa agaagaactc
     1081 attcctcttt atggagtgaa agagatagaa aataaagtgg tgatataagt aaaaataaga
     1141 aaacaagacg tttatgatgt caaaacaacc attttttaca tttttggcaa aaaagtgtca
     1201 tgatacagta taatattcgt tgaacaggcc aataaaggtg ttctccccca cgagatttct
     1261 actttattgg ctgtttcttt ttattaaaat aaaagttgtg tgtgtaaaaa agatatagct
     1321 gattccaagt gacaatttcg tatagatttt tatggtattc gtagtgaaaa aacgagaacc
     1381 aaaaagttga tccgactttg ttgcttggat tctttttttg tcagcatatt tagaggtatt
     1441 tttttctttt ttttgttcgt gctgtaaggt taaggcaaga caagttagtt gggaaaaagg
     1501 aaagaaatgt ttatacttaa agaataacag aaaggaaggt cgcatgaata attttataca
     1561 aacattaagt gaaagaaaag gcgagttgct ggaagctgca tttcaacatc tgtccatttc
     1621 tctcatttct ttgctgattg cagcactgat tgctattcct ttagcgattt gggcagccaa
     1681 tcataaaaaa atggcagaag tcttattgca gatcacgggt gtgctccaaa cgattccttc
     1741 acttgcctta ttaggtttac ttatcccatt tgtagggatc ggaactgttc cagcattgat
     1801 tgcacttgtt atttacgctt tgcttccgat tttccaaaac acgtatattg gtctagctga
     1861 aattgacccg tctattgaag aagcagcggt agcatttggt atgtccagaa tgagacgctt
     1921 gctgaaagta gagcttccca tcgcattacc tgtcattatc tcaggtatcc gaactgcctt
     1981 agttttaatc atcggtacgg ctactttggc agcattgatc ggagcaggtg gattagggac
     2041 atttattttg ttaggtattg accgaaatac acctgttttg acattgattg gtgcgatcag
     2101 ttctgccttg cttgcaatta tattcagcgg actgattcgc tggttgcagc ataagaaacc
     2161 tcgatattcc atcattactt tagcagcagt ggtgtgttta tttggcggcg tttctttata
     2221 tcagtctgcc ttgtttaaaa atgaaaccat cacgattgct ggaaaattag gagcggaacc
     2281 tgaaatcctg atccaaatgt ataaagaatt gattgaagac aacacaaaaa cagaagttga
     2341 attaaaaccg aattttggca agacgagttt tttgttcaat gcactggatc aaggtcaaat
     2401 cgatatctat cctgagttca caggtactgt cctagaaagc ttggtgaagg tacctgaagc
     2461 aatgaaaagt gctgatttga caaaagaaaa aacatatgac gaagcagaag aattattgaa
     2521 taagcaattc gatatgacat tattaaaacc aatggcttac caaaatacgt atgccttggc
     2581 agtcaagaga tcttttgcga acgaacatca acttaaaaag atttccgatt tggcagctat
     2641 ctctgatcag atcaaagcgg gattcacact ggaatttatt gatcgttcag atggatataa
     2701 aggaatccaa gaagcatatg gcttgaattt ttcaagtgta caaagcatgg agccaagttt
     2761 gcgttaccaa gcaatcaata atggagatgt caatattgtg gatgcctatt ccacagatag
     2821 ccagctcaag gagtacgatc tagtgactct agaagatgat cgagggttat tcccagctta
     2881 tcaaggcgca ccgctgatga aaaaagattt tgctaaagaa catcctgaaa tcgttaaagc
     2941 actgaataaa ttaagcggaa aaataacaga ggatcaaatg attgatatga attaccaagt
     3001 caatgtcgaa aagaaaaagc cgacagaagt agcacgaatc ttcctgaaaa atgaaggatt
     3061 agtaaaggag gaagatcagt gactaaatta atcgagttca aacatgtgca aaaaaagtat
     3121 gatggaaagt atgtcatcga tgacctaaat ctggcaatca aaaaaggaga aatctttgtt
     3181 ttggttggtc cttccggtag tggaaaaaca actactttga aaatgatcaa tggattatct
     3241 aaaccatcag caggagacat ctacttcaaa ggaaaatcgt taaatgaata taatctgcag
     3301 aaaatgcggt ggaatatggg atatgtgctg cagcaaatcg ctttgttccc gaccatgaca
     3361 gtcaagcaaa atattgaagt catccctgaa atgttaggtt gggaaaagca gaaaagagca
     3421 gaccgtgtag atgaacttct tcaaaaagtt ggcttatctc ctgatattta tcgagatcgt
     3481 atgcctagag agttgtctgg aggagaacag caacggatcg ggatcatccg agctattgct
     3541 gcaagcccag atgtgatttt gatggacgag ccatttagcg cattagatcc gatttcaaga
     3601 aactcattac aagaattggt tttgtcctta cacgaagaat tgggcacgac catcgttttc
     3661 gttacgcaca atatggaaga agcaatcaag ctaggtgatc gtattgcatt tatgaaggat
     3721 ggagaaatta tccaatgtga cacaccagag cagttattga tgaatcctaa aaacgactac
     3781 gttcggcatt tctttgatga accgaaacag acgaaagagt ggcgagtaga agatttagtc
     3841 gtcaatggat atttcttaaa tgaaatacca gaaaatgctc gtcaacaagt ttgctttgat
     3901 acgcctatga aagaagtata ttcgcttctt tcggtgtatc caagcattgt gatagtagaa
     3961 aagcaaagaa gtattgggtc gctgacaagt aaagaaatct ttgctttttt aagtcgagag
     4021 gaggaaggaa atgaaaacat atgatgcaat catcatcggt tcaggtgtga gcggcttaag
     4081 tgctgcttat ggattgaaag aagcaggtaa aacagtacta gtggtcgaag aagatctatg
     4141 gggcgggact tgtcctaacc gtggatgtga tcctaaaaaa gtcttgttaa gtgcagtaga
     4201 ggcacgtaat cgggtaaaac aattgagtgg aaaaggtttt aacgagatcc caactgccaa
     4261 ctgggaagaa cttcaaaaat tcaaacgaac atttacggat ccagtcccag aaagccgaaa
     4321 aaaacaatta gcagaagctg aaatcgatca tctttcagga accgctcgtt ttttggatga
     4381 ttcatctatt gaagtcaacg aagaagtctt ccatgcggat tacttagttt tggcaaccgg
     4441 gcaaagacct acgatcttac cagtggaggg aaaggaatac ttgaaaacta gtgcagactt
     4501 tttatcattg cctgtactgc ctaaagaaat catttttatc ggtggtggtt atattgcttt
     4561 tgagctagct acgattgcca atgctgcagg gagcaaagta accattgtcc atcataatca
     4621 acggccatta aaagaatttg aggcgtcttt ggtagaggaa gccgtccatc aaatggaagc
     4681 atctggcatt cagtttgctt ttggtgttga aacccaaaag atcatttcag aaggtactcg
     4741 ctatcgttta gtcggaaaag agacggaatt agtagcagat atgatttttt gtgcgactgg
     4801 gagacagccg aatacagaat ctttagcact tgagcaagcg aatatcgtct ttgataaaca
     4861 cggaattgca gtcaatgatt atctgcaaac gagcaatcca aaaatttttg cgtgtggaga
     4921 tattgtttca aggaaaaccc caaaattgac accagtcgcc acttttgaag gaaattatgt
     4981 agctaagcgg ataacggatg caacaagcga acctatcaaa tatccgatta tacctacgat
     5041 cgtctacgcc agtcctaaac ttgctgaagt aggagttaca aaaagtcacg cctcttcgtc
     5101 agatcaagtg gtagagatgg atcttaccag ttggttcacc tatcatcgtg tcaatgaacc
     5161 agttgctaag gctgaattga cctttgacca gcaaaattat ttgattggtg ctgcagtgat
     5221 tagcgagcaa gcagacgaat tgatcgatga tttgacactc gtcatcaatc aaaaattgac
     5281 taaaaaagag ttggatagct atatcatggg gtatccgaca ttggcaagtg atctctccta
     5341 tttattgaaa taatcagcat gataactaaa gcgcttgttg ctttttcctt cttgtgctac
     5401 actttaaaaa atgaatacct gtttctgggg atgtcgtaga cgacatgaga gtaagttgtg
     5461 aacttagacc cattgaacct gtcagttaat actggtgaag ggagaaacat agcagacgct
     5521 tgaagcgggt tactatgtcg tgcccatttc aagcgttttt tgttattcat attagaagaa
     5581 aggaggtaac aaaatgaaga aaaatcttta tccagcagtc agtatggcat tcattttaat
     5641 tatttggcag attgttgtca tagtttggaa aatacctgcc tttattttac ccggacctgc
     5701 tgctgtattt tctgcattag cggcagatgc acaagtatta ctttcccatt ctgtcacgac
     5761 attaaatgaa gcagtgcttg gtttggtaat agctagcgtt ctttctttta ttactgcctt
     5821 ggcaatggat tattggaagt ttttagaaat gtctttttat ccgttactag tgatttcaca
     5881 aatgttgcca atcatggtgt tagggccatt acttacccta tggtttggtt tcggtatgct
     5941 tccaaaagtg atccttgttg tcttgataag ctattttccg atcgtagttt ctttttcgga
     6001 tacattgagg aaagtatcaa aagagcaaat catctttttg aaaacgatgg gggcagatac
     6061 agggaagatt tatcgaatat ataaaatacc agcgggttta tccggcttct tttccggttt
     6121 aaaagtggct gctacttatt gtgtcagcgg agcagtcgtt ggagaatggc taagcgctca
     6181 agcaggctta gggtattaca tgatacgcgt aaaaaacagc taccagatcg ataaagtttt
     6241 tgctgcgatc atttgtgtca ttctattgag tttattgctg aatggcgctt gttcattatt
     6301 gaaaaaaggg tattatcgta tgctttatat tttttaagag aaggggatca aatgaaaaaa
     6361 ttatggcttt tattaccgct actgttgctt ttatccgctt gtggcactgc aaaagaaaca
     6421 agtagcaaac aagaaataaa ggatttgaaa aaagtgacac ttgttttgga ttatgtaccg
     6481 aatactaatc atactggcat ctacctagca aaagaaaaag gctattataa agaggctggt
     6541 ttaaatgtcc aaatcatcga accaggagat aattcgacaa gtattggtct agtaggtgcg
     6601 gacaaagcac aatttggtgt aagttatcaa gaagatgtca cttatgctca cgcagatgga
     6661 cagaatatac cagtcaaagc aattgctaca gtgatcaaac ataatacttc tggattcgcc
     6721 accctatcag acagtaacat ccattcacca aaagattttg aaggaaaaac atatgcaggt
     6781 tggcaaagtc caagtgaaga agctgtctta aaagctgtga tggaaaaaga cggcggggac
     6841 ttttcaaaac tgacaatggt aggaagcaat ggagaagggc cagaaagctt aggaaaatcc
     6901 tcagatatcc aatggtactt tgaaggttgg gatatgatca aagcaaaaga agcgggtatt
     6961 gaactaaact atatcccatt gaaagaatta gatgaacggt tagattacta tactccggta
     7021 attattacga atgatcaact gatcaaaagt gatccagaat tggtacagtc ttttatggat
     7081 gccacgaaaa aaggctatca ggaagctatt aaggatccaa atgacagtgc taaactgttg
     7141 caaaaatatg caaaagaaaa tgatcggacg tttttagaag aatcacaagc attcttgtca
     7201 aaaaattata cggatgatcc tgagaattgg ggattgatgg aagaaaaagt ttggcgcaat
     7261 tatacagctt ttatgcagga aaacggattg atcaagcaag atgtaccttc gcaagaacta
     7321 ttcactaatc agtttataaa ataggagtga tagatatgtc aatccaaatc agccacttga
     7381 atgtagtcat tgaaaacctg aaaatattag aagacatcca tttcactatc cctaaagata
     7441 cctttacatc gattgtcgcg ccaagcggag ccggtaagtc aacattgctg aaaactttaa
     7501 caggagtcca gcctatgact tctggaacga tcaaagtaga cgatcaaaaa gtaactggtc
     7561 tccatacagc atttagttat atgccgcaag aagatatgtt acttccttgg ctgagcgtct
     7621 atcaaaacgt tacgttatat caaaaaatca atcatctaac aatcaatgaa gaacaagtaa
     7681 gggattatct ggatatcttt gggttaaacg gctatgaaca ttttttgccg gaacaattat
     7741 ctggcgggat gaagcagcga acggccttgt tacgaacaat catgaatcct tcttcttact
     7801 tgcttcttga tgaaccattt ggagcgttag atgctatgac cagagggcag atgcaagact
     7861 ggatgttgaa gctgcctaaa aaagcaaagc ggactacttt acttgtgacg catgatatcg
     7921 aagaagcaat ttatttatca gacaggattc ttgtgctttc cgcccgtccg gcacatgtga
     7981 ttgctgagat tcaagtgcct gaaaaacgac ggtcacgtga atggctactg cagcaatcag
     8041 agttgaagca aacgatttat cagttattgg caggtgaatt agatgttaag tgatgctcat
     8101 tgtcatttag atgggagtca gagtttagca ctccttcagc aggaacacac gattttgacg
     8161 atcatcaatt gtgattcgcc agaagaatgg aaggaaaaca gacagcttgc agcaagtaag
     8221 actcaagcct taagttacgg tatccatcct tggaaagcag atagctatac gtttgaacaa
     8281 gttgagcctt ttttgaaaaa agcaaggatc atcggtgaaa tagggttaga taatatttgg
     8341 acgaatgtac cgatgactac acaaaaaaaa gtatttgagc gacagcttgc ttttgcagcc
     8401 ataaatgaga aacctgttgt actgcacaca aaaggatgcg aaaaagagat cttaaattat
     8461 atccaagctt accctaatca ctatttgatc cattggtatt cttctttgga ctatcaacaa
     8521 gactatattg atttaggctg ttatttcagc attggtcttg atttgaaaaa gaatccagca
     8581 gtctggcaac tagctaaagc agtcccaatc gaccacttac ttattgaaac ggatggacta
     8641 catgcagcag agtgggcttt aggggggatt ttttcagaaa aagattatgt ctcactgctt
     8701 gaagaacagt taaagacaat cgctgagatc aaagagctat cagttgaaga agttaaaaaa
     8761 aatacttatc aaaacttgga acgtttcatt agattaggta aataaaaaag agatgtgaca
     8821 caactagtgt cgcacctctt tttggctttc tttgtataaa agtaaactgt ttgattaata
     8881 aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca
     8941 taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga gtagtcacca
     9001 tttaagtaag aagaatctaa ttggtaacgt ccgatgtaac gtccgttcgt tgctgtgtaa
     9061 gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtgct tgctggagta
     9121 gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc tgcttgtttt
     9181 tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt ggactggtgc ttcttgaacg
     9241 gctgcttgag gttcagcagc tgcttgtgca gagccttctg ttgggattgt taattgttgt
     9301 cctgagta
//
LOCUS       DACCVH010000100         9284 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.100, whole genome shotgun sequence.
ACCESSION   DACCVH010000100 DACCVH010000000
VERSION     DACCVH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.100"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            113..805
                     /locus_tag="IVV98_002530"
     CDS             113..805
                     /locus_tag="IVV98_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP7808125.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            1233..1625
                     /locus_tag="IVV98_002531"
     CDS             1233..1625
                     /locus_tag="IVV98_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808126.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(1798..1980)
                     /locus_tag="IVV98_002532"
                     /pseudo
     CDS             complement(1798..1980)
                     /locus_tag="IVV98_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1967..2164
                     /locus_tag="IVV98_002533"
     CDS             1967..2164
                     /locus_tag="IVV98_002533"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808127.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(2207..2782)
                     /locus_tag="IVV98_002534"
     CDS             complement(2207..2782)
                     /locus_tag="IVV98_002534"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP7808128.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(2937..3463)
                     /locus_tag="IVV98_002535"
                     /pseudo
     CDS             complement(2937..3463)
                     /locus_tag="IVV98_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3920..5431
                     /gene="gadC"
                     /locus_tag="IVV98_002536"
     CDS             3920..5431
                     /gene="gadC"
                     /locus_tag="IVV98_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HAP7808129.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            5444..6844
                     /locus_tag="IVV98_002537"
     CDS             5444..6844
                     /locus_tag="IVV98_002537"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003134257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAP7808130.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(7009..8444)
                     /locus_tag="IVV98_002538"
                     /pseudo
     CDS             complement(7009..8444)
                     /locus_tag="IVV98_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            8837..>9284
                     /locus_tag="IVV98_002539"
     CDS             8837..>9284
                     /locus_tag="IVV98_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HAP7808131.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         3103 a         1464 c         1630 g         3087 t
ORIGIN      
        1 cctttttaaa taatttttta gacaaaaaac agaaagtgtc taaagaaagc ttgacgaaga
       61 aaataatttt taataactta tttaaggaaa ttttttgaag gagaagataa aagtgagaaa
      121 aaagattatt attaatgctg gagtaattat aggattgatg ttagtaattt tctccggaaa
      181 gcaatatgct gataatattt tattatgggg aggggaagat aatattgaaa agatcaacaa
      241 caatttaact atattagaca cagctctaga aaataaagag caaaaaatta gtattttaaa
      301 ttcacaattg tcttcaaaca accaaactct tgaacaacta agaactaata ttgaagtttc
      361 caaacaaaaa gtggcatctt tagaaaacga caagaatcaa ttagtatcag agaaaactaa
      421 tttagaaaat caattgtcag caaaagactc tgaattgcaa ggaaaacaaa atgaaattaa
      481 tgcgaaaata gacgaaatta accaaaaagt agctgaaata aatcgattaa atagcgattg
      541 gaataatcgt ttacaaaatg aaaagaacaa atttaatgaa gaacaatcta ctattaatag
      601 tttaaaccag caaattaatc aaatgttgag tgaaaaaaat aacattcaaa atcaactgca
      661 agctactcag caaaagctag aagaagaaaa gtcaaaaaat agtagtttga ataattacat
      721 tgaaaagctt caaaaagcta aaaatgatgt agaggatacc gcaaataaag cacaacaaat
      781 tgtaaatgaa catacaatcc aatagatata gttttaattt aacaaatggt atgtttggag
      841 ataatgagat agaatataaa tgtcataata ttatacaatc taaacaccgt ttccttttct
      901 atttttgatg acatcagtat atagctactc gaaagagtag tctttttatt attctcgctt
      961 attattgata tgaaaatttc gatttgacaa aaggtaccga ataattttgt aatatgaatt
     1021 attatcaaga agtaattatg atgataacat atggaaacta gttagtaata ataacaggtg
     1081 attaaacttt tgaacgactt gtaattctat attttttctt ttaagtaaaa aatataggtg
     1141 attttttttg acttcatatt tataataaag acacgtaaat caattatttt tcattttact
     1201 ttaactaata atgtttattt ggagggatta ttatgttaga tgatagattg acgtgttcta
     1261 attgtggtac attattttac tatgaggaag ttagaaatat tgtaaaacat agaaaaaaag
     1321 aaatgcctat acgttgtcca aattgcaatg aagttattaa gcgaaagttg tctcatggtt
     1381 attttgtcag ctacgaacta tatgaagaaa gtaaaataaa tctgaaaaaa aaaccaaaat
     1441 actataaaaa tttgaaaact ggagctatta taactgaaaa agaatttaaa aatttagtga
     1501 ctgaagaaga aagcaggttt tataatttgt ctggtaatat ttgccctgga tttatggatc
     1561 agattattga aaatgagtca attgaatcaa ttgaaaacta tgttcctgtt gacttaccaa
     1621 aatagaaaaa ataatcctgt ttttacagtg aattatttta attttgattt tcaataaaaa
     1681 tatattacaa taataatcgt aatagctaat gaaacaattt ctcaatcttt ttaccactcc
     1741 aaacagggag cgtcaataat tttgtgtaaa taactcgtcc ttctgcaaaa taatgggtta
     1801 ctcagtaaac attgaagcta atgtatccgt cacttgttgg aagcctttat ggcttctatt
     1861 taagaatttt tgattgtatg tatcaaagat ggatactagg aaacgctcta gtgattcttc
     1921 attttgaaac tgctcttttc tgcggctgta tttcttgatt tgtttattga aagattcgat
     1981 tgtagaacca gaaggaatgg agaacacttt tgaactttac aacaaaacta ctgttgataa
     2041 attaattcca attttagttc caactgattt aaatggtcat gatgttttac ttcgttttaa
     2101 cggattttta ggtgaggatt atagatacct aaaaatttct gatcctcaac ctttaacaga
     2161 ataataaaaa acgtgtaatc aattatttga ttacacgttt tttatttcaa tcttcgttgt
     2221 agtagtggtt gcgacatacc gaaaggtaat cttcattacc tcctactaca atctgttcac
     2281 ctgaataaac tggaatacca tcaacaatac gagcattcat tacagccttt ttattgcaaa
     2341 aatggcaaat agttttaatt tcctcaattt tatcagcaaa tgtcaataat gcttcggatc
     2401 ccttgaagag attattttga aaatcattct tcaatccata gcaaattact ggtacttcct
     2461 cattcattac gataagtgat agatcaataa tattctctct acttaaaaat tgagactcat
     2521 cgaccaaaat acaatcaact tttccgtact gatcaataat ctccactaat tctccgtaca
     2581 catccatttc agaagtaatt gcaatagctg gtttcgaaac acctatacga ctctcaactt
     2641 ttccaaatcc tgatcgagta tctattgcgc ttgtcattat gataactctc ttcccttgtt
     2701 cttcataatt atgagccact ttcagtagct caatactctt tccactattc attgttccat
     2761 atctgtaaaa taattgtgcc attaaattta ttcccttctt ttacaattca attattcctt
     2821 aattccatct gcttttatgc agctgctcgt ttattccttg atatgtctat aacatctact
     2881 atccctaaaa ccaatttata agccattaga gatggtattc ctgaacatct ctcatattgt
     2941 tttttgagtg gtatatcatc tgaaaaactg aaggaatcat gaaaatagcg acatacttat
     3001 catttagagt tctaacttta aatgcattta cttcttcagt cagcacttta gtcatgttgg
     3061 acatggtttg gggcgtgtag tgatgcccat acattttctc aatcaagtct gcgatttccg
     3121 acatggtaat accttttcgg aagaggtgaa tgacggtctc ctctaatgtg tcattcgtcc
     3181 gtctataagc aggaacagtc tgttgcttga actcgccatt gcggtcgcgc ggaatctgga
     3241 gatgaagttc cccatactcg gtcttgaccg tacggtcata ggagccgtta cgagaattac
     3301 ccgtgttaaa accaatgcga tcgtactttt cgtaatcgag gaaagccgtt aactccgttt
     3361 tgagaagcgt attgacagct ttttccaaat ggacacggaa taatccattc aaatcgcctt
     3421 tgttcgctag agtctttagg atttctgtag taaaatcgtt catatggaag tcctcttttc
     3481 tgtgaatgtg ttgtggtaac tctattctac agaagggact tccttttttc tatttacaca
     3541 aaatatttta cactctcaac aaaagtatct tcgattaata cttgctcaag ttatgtgcag
     3601 ctacgaaaaa gtaggtaccg aggtactttc tttttcgcag ctttttttgg acttatgaga
     3661 agtacattcg ctggaagaat acgatataaa acgagctttt tcactaaaga tattaataga
     3721 gtgaaagaaa caagcttttg ttgtcagttt tttcactttt ctaaaaatga aaataaaaaa
     3781 ttctggaagt ggagaagaat tttgcttgct atactttgtc ttgtagaaaa gaggtagaca
     3841 aaataatgca agctcaaata agcgattttc cataaccttg gtaggaatga caaattaaat
     3901 aggaaaggga agtaataata tgaataaaaa aaagttatct ctattcggtt tttttgccct
     3961 gacagcttcc atggttttga ctgtttatga gtatccgacc tttgcaacat cacaattaca
     4021 tttggttttc tttcttcttt tgggaggtat tttatggttt ctaccagttg ctttatgtgc
     4081 tgcagaaatg gcaacagttg aaggatggaa agatggtggg attttcagtt gggttagtca
     4141 aactttagga gaacgttttg gttttgcagc tatttttttc caatggtttc aaattacagt
     4201 aggttttatt acaatgatct acttcatact aggagcgctg tcgtatgtaa ttaattttcc
     4261 agagcttaat acagatccat ttatcaagtt tattggtgta ttagtcattt tctgggtact
     4321 gactttttca cagttgggcg ggaccaatcg taccgctaaa attgctaaag caggatttgt
     4381 cattggaatt gttattcctt cgatcattct ctttggttta gcagcagcct actttatcgg
     4441 cggtaatccg attcaaatgg ctattaatgc gaaagctttt attcctgact tttctcagct
     4501 ttcaacttta gtagtatttg tatcttttat attggcttat atgggcgtag aagcttcagc
     4561 atcacatatt aatgagctgg aaaatcccca aagaaactac ccattggcaa tgtttttact
     4621 agtgattttg gccatcgcct tagatgcaat cggcggtttc tcagtagcag cggttattcc
     4681 acaacatgac ttgtctctca gtgctggtgt aatccaaaca tttgaaacgc ttattttaca
     4741 ttttaacagt catttacatt ggttggtaaa agtgattgct ctcatgattg cctgtggcgt
     4801 tatgggtgaa gttagttctt gggtagttgg tccatcacga gggatgtttg cagctgctca
     4861 gcgaggtctg ttaccagttt tcttccggaa aactaataaa caagacgttc cagttccgtt
     4921 gattatgata caaggaatta tcgttactat ttgggcagca gtcttaactt ttggtggagg
     4981 aggcaacaat ttatcattct tagtagcaat ctccttaact gttgtcattt atctcgtagg
     5041 atatttacta tttttcctag gttactttgt attagttttt aagaaaaaag acttaaaacg
     5101 aacttacaat gtaccaggaa aaactgttgg caaaacgatt atcggtggaa ttggttttat
     5161 tttatcagtg ttcgcattgc ttatctcttt tgtaccacca gcttcaattg cagctagtga
     5221 gcaccgaaca taccaaatca tactacttat tagctttgta gtgactgttc ttttaccttt
     5281 tatcatttat gaagtacatg ataaaagtgc tcacacaact attgaggaac ctactcacgt
     5341 gaaagctgaa gacgttaatc ccgctgttta tccagctgct agaggagagc accacgttac
     5401 aaaaaatgat gaacatattt taaaacatta ggaggaattc attatgttat acggaaaaga
     5461 taatcaagaa gaaaaaaact atttggaacc aatttttggc tctgcaagtg aggatgttga
     5521 cttgcctaaa tataagttaa acaaagaatc cattgaacca cgaattgctt atcaattagt
     5581 acaagacgag atgttggatg aaggaaatgc gcgattaaac ttagctactt tttgtcaaac
     5641 gtatatggaa cctgaagcag tgaaattgat gacccaaacg ttagaaaaaa atgcaattga
     5701 taaatcagaa tacccacgaa caacggaaat tgaaaaccgc tgtgtaaata tgattgctga
     5761 tttatggcat gctccaaata atgaaaaatt catgggaact tcaacgatcg gctcttcaga
     5821 agcctgcatg ctgggtggta tggccatgaa atttgcttgg cgtaaacgtg ctgaaaaatt
     5881 aggtcttgat attcaagcaa aaaaacctaa cctggtgatc tcttctggtt accaagtttg
     5941 ttgggaaaaa ttctgtgtat attgggatgt ggaactgaga gaagtcccaa tggatgaaaa
     6001 acatatgtca attaatctag atactgtcat ggattatgtg gatgagtaca caattggtat
     6061 tgtaggtatt atgggtatta cttacactgg tcgttatgat gatatcaagg gtctgaatga
     6121 tttagttgaa gctcacaata aacaaactga ctataaagta tacattcatg ttgacgctgc
     6181 atcgggtggc ttttatgcac catttactga acctgatcta gtttgggatt ttcaattgaa
     6241 aaatgttatc tcaattaatt cttcaggtca caaatatggt ttggtatatc caggtgtggg
     6301 ttgggtctta tggcgtgacc aacaatactt accagaagaa ttagtattta aagttagtta
     6361 cttaggtgga gaaatgccaa ctatggctat caacttctct catagtgcag cacaactaat
     6421 tgggcaatac tacaactttg tacgctatgg ctttgatggt tatcgtgata ttcaccaaag
     6481 aactcatgat gttgctgttt atttagccaa agagatcgaa aaaactggta tttttgaaat
     6541 cattaatgat ggatcagaat tgccagttgt gtgctataag ctgaaagaag atcccaatcg
     6601 cgaatggaca ctatatgatt tatctgatcg tctgttaatg aagggatggc aagtcccagc
     6661 ctacccatta cctaaagact tggatcaatt aattattcaa cgcttagttg ttcgagcaga
     6721 ctttggaatg aacatggctg gtgattatgt acaagatatg aaccaagcaa ttgaagagtt
     6781 gaataaagct catattgttt atcataaaaa acaggatgtg aaaacgtacg gctttactca
     6841 ctaaaattct tcagagaaat ataaaagaag ttaattaact aataaaagga gttgtgatta
     6901 ccacacagct ccttaaatct atttgaataa atatatgata ttcatttgtt acactctcaa
     6961 tcttagctgt tgttctattc atcattactc ttattgtaag tagttcagtc aaatttgctt
     7021 gttcaattga tcgataacag tatgaattgt ttgaaaagta atcggatata taattgtttt
     7081 ctcactacct aagccttctt ggtataaaga actatcgcaa agtataatcc gctgagtaca
     7141 aaagaaagtg tcgtctacta tttctctaag ttgtttacaa atgatattac taatagaaaa
     7201 gtgttctccc aaaatgtctt ctaactgttg tcgatagtat aaatacctaa agtctgacgg
     7261 agctactatg aacacttcaa ttggagattt ccgtttatgc tcatttaaaa gacttaaact
     7321 aatggttagt ttacgaatag aattctcatt ccaacgcaga aataaattgt tttgttttcg
     7381 ccattgttca agaatttcat gaacttctaa gtacaaagcg cgttgctctt catttaacaa
     7441 gtaagtctta tcaggttgaa atatctgaat atcagcccaa agtgagcgga taaacgggag
     7501 aagtgcttta tcaaaaagta tctgattttc ttcagatata ttcagagata agataagttt
     7561 ttgactgagc tcaatcacca aagggttatc tgctacatgg ttttgataaa caacgttcaa
     7621 gtctttttgt aacaattcaa agttatcgca tagataattt ctagagttga atagaaagta
     7681 gatataaagg cattcatctt cgtcatgaca taaagagaaa gaaagttgct ctaatccttt
     7741 ctgtattagc tgaaacaagg gagtatgtcg ggcaactctt ttttcttcct gactaaaata
     7801 tattgggtta gtcttagatc tctgcaaacc gatagcgata cctaataaaa taaattgttt
     7861 ttcaactgta gggtaacttc ttgaaaaaaa tgtttttcta cataatcaat caattgttga
     7921 ccgctttgaa taattgattt atttagctgg atcaactctg tccgatttgt ctcatagatt
     7981 atcgttagta acaaacttcg ataatccttt tcaggaattt caaaatggcc atcagcattt
     8041 aagtactgca tttgtttaaa aaaattaatc aactcatttc gtaagttgta aactttgctt
     8101 aacgaaatga aggtagtatc agctatatta ctccaattgt gttcccctga taaataatgt
     8161 cctagtacat tgaaaaagtc agagcgctga tagatgagtt gagtgagtgc caacctcgaa
     8221 aacgaagagt cgaatgcgac tgtaaagcta cttctagatt tctccactga aataatttgc
     8281 tgatggagta tgtcggtaat gcattccaag tcgttagtga cagtgagtgg gcaaacgttc
     8341 aattgatctg ctatttcgcg aatctgaatg gtcccttttt cgtgtaattg ctcacaaatg
     8401 taaacttgac gaaaaatact tttctccaga taggtttcca acatagtact cctcctagtc
     8461 attttataca taactattat aactctacca atcggaatag tcctgtaata tattgaatca
     8521 aaaatataaa ttataaaata attagatggg gtatttggtt taagtatccc ttatatagta
     8581 ataaatttat aggtgtgatt ctcgaattaa tacccgaaaa tgtgagagaa tttttatgga
     8641 ttttttagga tacaaattaa ttatttttgc ttttatcctg attaccagtc cagtactgtc
     8701 ggtatcccat tttgcagcaa aatcatgttg ataaagtgac aagaagactg atgagatata
     8761 ttatccaaat tgagaagata attaatcgga ttcttgagta taccctactt tttaagaaag
     8821 tagggtatac aagcgtatga ataaagacat aactttccct gtgatggacg ttcggcttgt
     8881 tccaattacc aaaatacagg cgaacgatta taatcccaat cgagtagcgt ctccggaaat
     8941 gaacttattg gagctttcta tcattgaaga tggctttact caaccattag tttgttatta
     9001 caaggaaaaa gaagagaagt atatcttggt tgatgtgctt cataggtatc gtgttgctaa
     9061 ggaaagactc aacttaaaag ttgtaccggt aacagttatt gataaaccca tagaagaacg
     9121 tatggcttca acaattcgac acaatcgtgc aagagggacc catgaaataa gaggaatgga
     9181 aattgtcatc caaagattag taaaaaatgg atggtcagac aagagaatat ccaaagaatt
     9241 aggcatggac attgaagaaa tttttcgctt taagcaagtg tctg
//
LOCUS       DACCVH010000101         9089 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.102, whole genome shotgun sequence.
ACCESSION   DACCVH010000101 DACCVH010000000
VERSION     DACCVH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.102"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            126..1547
                     /gene="arcD"
                     /locus_tag="IVV98_002540"
     CDS             126..1547
                     /gene="arcD"
                     /locus_tag="IVV98_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP7808132.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            1561..2679
                     /locus_tag="IVV98_002541"
     CDS             1561..2679
                     /locus_tag="IVV98_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP7808133.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(2739..4031)
                     /locus_tag="IVV98_002542"
     CDS             complement(2739..4031)
                     /locus_tag="IVV98_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7808134.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            4181..4741
                     /locus_tag="IVV98_002543"
     CDS             4181..4741
                     /locus_tag="IVV98_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7808135.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            4870..5247
                     /locus_tag="IVV98_002544"
     CDS             4870..5247
                     /locus_tag="IVV98_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP7808136.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            5180..7252
                     /locus_tag="IVV98_002545"
     CDS             5180..7252
                     /locus_tag="IVV98_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7808137.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(7463..8410)
                     /locus_tag="IVV98_002546"
     CDS             complement(7463..8410)
                     /locus_tag="IVV98_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7808138.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            8656..>9089
                     /locus_tag="IVV98_002547"
     CDS             8656..>9089
                     /locus_tag="IVV98_002547"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP7808139.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
BASE COUNT         3016 a         1685 c         1916 g         2472 t
ORIGIN      
        1 tgtaaaaagt tcataatatc caataatatg aataaagttg ctttttgtta agcaagagca
       61 gttgcaaaat agaagggaat cttttgcaag tgatttgttc aattttataa gtgagggtga
      121 tggaaatgga aaagaaatcg acgggtatta gcaaatgggg actggttgct ctggttgtca
      181 gttcgtcaat cggaagcggt gtgtttggga tcacaagtga tctggctagt tctgcagctc
      241 cagggccagc gatcctttca tggataatcg ttgggattgg tattttagct ttggtattat
      301 cgctgaatca tttaggagaa aagcgtccag atctagatgg tggtattttc ggttacgcgg
      361 aagcttcatt tggtaaatta ggtggcttca tcagtggttg gggttactgg ttgtctgcgt
      421 ggctgggaaa tgttgctttt gcaacgatgc tgatgagcgc catgggagaa tttttcccga
      481 tattcaaagg tggacaaaat gttccttcta ttttatttgc aagtattttt atttggggtc
      541 tgactttatt agtaaacaat ggagttgaag gagcgagcgt catcaataca atcgtgacga
      601 tctgtaaatt agtgccatta ttcctatttt taatatttgt atttatcgca tttaaagtga
      661 atatattcac tgctgatttt tggggtaacg tatctgataa tctagtgaat ggaacagggc
      721 agcaaggaac gatctggttg cagattaaag gttgtttgat ggttatgatg tgggtctttg
      781 tagggatcga aggcgcaagt gttttagcca accgcgcgaa gaaacgttca gaagcccagc
      841 aagcatcgat cattggtctg ctttgtttat tgtttatcta tatccttgct tcgatcttgc
      901 catacggcgt cttatctcaa gaagagttag caactatttc acaacctgct atggcaaata
      961 ttttaaaagg aatcgtggga aattggggag cagcgctgat caatatcggc ttgattattt
     1021 cgatcattgg ttcttggttg tcttggacga tgctcccagc agaaacaacg atgttgatgg
     1081 ctcgagacgg tctgttgccg aaaggttggg gaaaaacgaa taaaaaaaat gccccaactt
     1141 attcgttagt tgttactgca atcttgacta atctattctt attgactttc ttagttactg
     1201 attatgccta tcaatttgcc tattctttat gtacagcggc aattttgatt tgttatctac
     1261 ttgtcgggat ctatcaagtc cagttttctt taaaagaagg aatcaaaaaa caagtagtga
     1321 tcggtgggat tgctgtagtt tttgaattga tgggcatcat tttagcagga ttttcttatg
     1381 tccttttatg tagtattgcc tatcttcctg gtttttgctt ctactggatc gcttgtcgtg
     1441 aaaccaaaca tcaaattacg ggaaaagaaa aagtaatgat tgggctgatt tgtgtggccg
     1501 cactgctttc aatcgggttg cttgctgtag gctggatcaa gatataaggg ggaaagaaac
     1561 atgaaaatcg caaatttcgg tgtagaagaa tggctaaata aatgggaaaa gaaagcggta
     1621 tatgatattg cacaaagctc gatcgaagca ttgacattag acgaactcgt tggcttagat
     1681 gggactagcg taagtaaatt tttcgaaaaa cgcaaaaacg aaccattgga ctatggctgg
     1741 atcgaaggat cagatgtttt caaacaagaa gtcgcttctc tttatcaaac cgtcgatccg
     1801 gaaaacatct tacaaacgaa tggagcgact ggtgctaatc ttttagctct atacgcgtta
     1861 gtggaagcag gagaccatgt tgtttcgatg cttcctactt atcagcaatt atatgacatc
     1921 cccaaatctt taggtgccgc tgttgacttt gttcatttga aggaagaaga agattggcag
     1981 tttgatttag aacagctaga agccttagtc aaacctgaaa caaaaatcat ctgtttgaat
     2041 agtgcaaaca atcctacagg cacattgcta gatcggaaaa ctttagaaaa aatcgcagaa
     2101 attgctcgta cagtagatgc atatgtattg atagatgaag tatatgcgcc tttaacggat
     2161 aaaggtgaat tcttgtcgat cgtagatgtc tatgaaaaag gtatagcaac caattcccta
     2221 tccaaaacct actccattcc aggtattcgt attggctgga cagctactgg acctgagttg
     2281 gcagaagttt ttcgaaagta tcgagactac acgatgattt gcggcggagt cctgtcagat
     2341 gatcttgctg tacatgcatt gaagaataaa gaaaaaatat tggcgcgaaa caaaaagatc
     2401 attacagaga accttgtgat tttaaaacaa tgggtagcca atgaaccgaa agttgaactt
     2461 gtcgctccca attacgtctc tacttctttc attaaattag ccatcgaaga agatgaccag
     2521 acattttgta tcaatttatt agaagaaaca ggagtactat tagtaccagg aagtgccttt
     2581 gatttaccga agcatgcccg actaggttac tgttgtaaaa aagaaacctt ggaaaaggga
     2641 ttattcctct tatctgagtt cttgaaaaaa caggcctaaa caaaaacact gcaaggacag
     2701 tctgtgacaa ctgttcaagc agtgtttttc atttacgctt attgtctatg agaaggagag
     2761 tgccctgaag ctatggagac tcctgaagct ttttcttctg cagtttcttg ctgatggatc
     2821 tcttgtgtat tgtgtcgtac aagcaagaag ttgaccaaaa caagaagaga agtcgaaaga
     2881 aagacgccgc gataaccaaa tgcactggaa acactggagc cgatcatagg ccctactacg
     2941 ttaccagttg cttggaaaga ttggttataa ctgaagatcc gtccagcagc ttgatgaggc
     3001 gaatattttg tgatcaatgc ttggacagca gggagcagac aagcatcaga gataccaatc
     3061 aaaaaacgta aggcagctaa ttgccaaaca ttcgtgacga atgccattgg gatataaacc
     3121 agaatcgcaa aacccaaacc aatcgcaagt attctttcac tcccaatctt gtcacctaag
     3181 cgaccaaatc ttggagcggc tatcaaagtg gcaatcccag gtatcgaagc aatgattccg
     3241 ctgatcaacg taacattccc atgtccatgc agcaattggc gaatgtacag actgatgatt
     3301 ggactaatgg aattgttgga tgcttggatg atcatcgttg tgacgaacat accgatgacg
     3361 acgtgtggat atttcaagtc tttgaaaatc tgtttggcag aaaccatgtt ttcttttttc
     3421 actgggacaa atttttcatg gacgaaaaac agactcaaca agaagacgaa aaataagatg
     3481 atccctgtaa tgaaaaaggt agggcgatag ccaaacgctg aagcagagat cccgccaaga
     3541 agcggtccaa gtaatgttcc tgtaacagaa ccagttgcta aggttccaag aacttgacca
     3601 cttttttctt ttggcgtccc agttgcgaca agggcagtgg cattactgat ataaccagaa
     3661 aaaatccctt gaagcagacg caatgcgact aattgataca cactagtcac gcaacccatc
     3721 aaagaaatga cgattgccat tcctaatgaa gcacgcaaca gcatcaattt tcttcctttt
     3781 tggtcggcta attttcccca ccaaggagag ataagcgtag tcaccaagaa agtagatgaa
     3841 aaagtcaatc cgctccaaaa gttcaattgt gacgtactat aattacctaa cgtatctatg
     3901 taaagtgaca taaaaggcat gactaaacta aatccgatac cagccataaa tgttccaaac
     3961 cataagacaa acaagttttg ttcccaagtt tctcttttcc taaataattt ttcctttatt
     4021 cttgcagcca attagactcc ttctttctga aaattttcat ctacagctct ttattataaa
     4081 ctacaatatg tagtttatca atgaaagtct cttttttctc tttctttttc gtggtaaact
     4141 gaaagagtga aggatttatt ttatgagagg aaacatggaa atgaaaaaaa gaaatctgtc
     4201 tcaagagaaa atcatcgact gctttcgaga actagcagaa gagatggatg ttcagcaaat
     4261 aacctttcag catttagcca aacgcttgga tatcaaggct ccctcgctgt ataaccattt
     4321 caaaaatatt cgtgatgtca aaacagcgct aacagcgaaa cttctgcagg aacttaatga
     4381 ccagctgcga cgggctcttg tgggaaaaag tggtcaggaa gcactgcaga tctatgcaga
     4441 aacttatcga tcctttgctt tttcaaatca agcagtgtat gagttactga tcagtgtacc
     4501 gcataccaat gaagctgttt tattagatgg aatccatgaa acgaatcaga tcattttgca
     4561 gatatttgag gcttttcaat taacgaaaga agaaaaagtt catcgaagca gggaacttcg
     4621 tagtatgatc cacggttatc tttccttacg ttttttagga tactttacaa aagaaccaac
     4681 aatcgatcca gaagacagct atttttggat gatcaataac tttatcgcta ctttgcctta
     4741 aacaatcaga ttcatttgta acaattttaa gatgttcatt aaatgaccct tttataagag
     4801 aaaattcttg caactttctt gaaaagtgac taagatgagt ctagaaaagc tgaaagaagg
     4861 agcacgagta tgtatcaagt aattaccatg ttcggggaca atgagccttg gtggtttttt
     4921 gaagactggg aagaagatat tgaagaagaa gaaacattcg agtctttcga agaagcacga
     4981 caagcgtacg aaaaacaatg gaacgaaatc catcaaaatt atgaatatat caatgcaaaa
     5041 agtaactttc tcagcgcctt ttggaatgac ggagatgagc gctggtgtga agagtgtgac
     5101 gatgatttac agcaatacaa gggacttgcg ttgttgaaaa atcatcagcc catcacagta
     5161 gaaagcagaa aggaatttta tgaaacaact aattctagcg gaaaaaccaa gcgttgcgaa
     5221 agacctaagc aaggtgcttg gtgctaatca aaagcacaaa aattattatg aaggacccaa
     5281 ggtgatcgtt acttgggccc ttggtcattt attaggattg aaaatgccgg aagatctgaa
     5341 taaggaatgg cagagctggc aaatggacac gttgccaatg atccctaaaa aactaggaat
     5401 caaaccactt cctaaaacag gacatcaatt aaaagcaatc aagcagctgg ctcagcgaaa
     5461 agatgtctca gaagcagtca ttgcgacaga tgccggaaga gaaggggaac ttgttgctcg
     5521 ctggatctta gagtatgtgc atttcaataa accagtgaag cggttatgga tctcttctca
     5581 aacagataaa gcaatcaaaa ctggattcaa gcaactaaga cctgcgaaag aatatgatgc
     5641 attgtatgaa tctgctcttg cccgggcaaa agcggactgg ctggtaggat tgaatgtgac
     5701 cagagcctta actgtgaagt acgcggataa tttatcagca ggccgtgtgc agacaccgac
     5761 actagcatta gtgagagacc aagaaaagaa aatcgagcag ttccgtccac aaacgtattt
     5821 cacgatcacg ttgcaagctg gaaaagaaca agccaaaatg cttcaaaaaa atcaatttgc
     5881 tttaaaaaca caagaagaag cacaaaaact tgttcaattg atcagtacaa gcaaaggaac
     5941 tgtcacagaa gtccaagaaa aattaaaaac ggaatctgcg ccattgcctt atgatttaac
     6001 agagatccaa agagaagcca atcaacgcta tggctattct gcaaagaaaa cattaagtct
     6061 tgtacaaagt ttgtatgaga cccataagat cgttacttat ccgcgtacag acagcaaata
     6121 tctgacaaat gacatgaaaa gtacgatgaa agaacgattg caagcagtca gcgactttgc
     6181 tcctgaggtc aagcagtatt tgaaaaacgg agccatcgtc caacagacaa aagtattcca
     6241 agacagtaaa gtgaccgatc accatgcact tttgccaact gaaaacagag cacgttatga
     6301 aaaattaagt aatgaagagc gaaaaatcta tcaaatgatt gtctctcgtt ttttaggact
     6361 gtttgctcaa ccccataaag tcagccaaac aaaagttacg gttgaatttg gtaaagaacg
     6421 attcattttt cggcaaaatc gtgtcgtcca agcaggatgg aaaggcgaaa ctgaaactga
     6481 gacggaaaca gtcaaatggg aaaaaggaat gagaatcaat cccgatttcg ccatcaaaaa
     6541 agaactatct gcaccgccta aaccattgtc agaagcaagc ttgcttggtc aaatggaaaa
     6601 atacagtctg ggaaccccag ctacgcgtgc agagattatc gagaaactaa tcaaatctga
     6661 actgatggaa cgtacccctc aaggactgca agtatctcct aaaggtaagc aattattagt
     6721 attggtaaat ccctctttag taacaccaga tttgacagaa agctgggaaa aagaccttga
     6781 agctattgct gcaggaaaga aacaagcagg aaccttcttg aatggaatcg aaaaagaaac
     6841 aaaacgcttg gtgaatgaga tcaaatcaag caaacaagaa tatcaagatt tctcgattac
     6901 ccaaaagaaa tgcccagaat gtggggccaa tctgcgcgag aaaaacacac gtgacggcaa
     6961 aatctatgtc tgcaccaatt cagattgcaa ctaccgcaga agaaaagatc caaaagtctc
     7021 taatcatcga tgcccgcaat gtcaccggaa aatggaaatc atcgaaggta aaaacggtgc
     7081 ttatttccgt tgtaaatacg atggaacgac agaaaaattg cttgataaaa aagagcagaa
     7141 gaagaaaatg accaaacatg aagaacgacg cttgctgaaa aaatatgcac aagcagaaga
     7201 accagaagaa agcccattag cagcagcact aaaagcagca atgaagaagt aataagatat
     7261 gaaagaggtt gtgatagaag tggtcagctt caagaaataa gaaggaattt acgaaaattg
     7321 cttctcaaat ttttgtgaaa tttcggctta tttccgaaga agctacttct ggaacaccat
     7381 ttattcggaa aaaaggactg tgacaagact tttgtcacag tcctttttca tttaaaaaaa
     7441 tgtttacttc atttgacgta tattattggt gaggcttcaa ttcatttggc ttcacttttt
     7501 ctgtttctct tatgatataa acaggacgct gtttcgtttc taagaagatt ttcccaatat
     7561 atttcccgat gattccaaga cataacaatt ggattccacc aatgaacagg aagatcgaga
     7621 ccatggaagg ccatcctgat gtaggatcac caaacaacaa tgcccgcaaa ataatgaaca
     7681 aaattgcaat accagaaccg acacaagaca aagcgccgat aaatgaagca atcgttaacg
     7741 gtgcatccga gaagttcacg ataccatcaa tcgagtagtt gaataatttc cagaaggacc
     7801 aagatgtttc gccagccaca cgttcgcggt tttcataaga aatatattct gttttaaatc
     7861 cgacccagct aaataatcct tttgaaaatc ggttgtattc tgttaattct aggacggcat
     7921 ccaccatttg acgagtcatc aagcggaaat cacgagcgcc atcgaccatt tctgtatcgc
     7981 tgattttatt gatcaactgg tagaattttt tcgcaaagaa actgcgtatc gcaggctcgc
     8041 cttcacgagt cgaacgccgg gtgccgacac aatcgatatc agaagtagtg atccggttga
     8101 tcatctcagg aagcagttcg ggcggatctt gcagatcaac atccatcacg gtcactaaat
     8161 ctcctgtaga agcttgcaat ccagcgtaca gagccgcttc tttcccaaaa tttctggaaa
     8221 atgagacaaa gcggacataa ggataagctg aggctagctt cttgattgct gctaacgtac
     8281 cgtcttttga tccgtcgtca ataaacaaat attcgaactc atgggcacct ttgaattttt
     8341 caacctcatc aaaaaaaaga ggaacagttt tttcttcatt aaaacatggg acaacaattg
     8401 atactttcat cgtttctatc ctttcaatcg tatgtttata tatggtttac attcaaaatt
     8461 taataaacct taaataacac ctttaaaatt tgattttacg taaaagaaca ggtattcttt
     8521 ttgtaaacta acgtatttag tttaccatgt ttcctcggtt tatcaaactt ttaagaacaa
     8581 tttttattag ttggcaagta gttttggata gagaaaaagg aggaagttcc agtctattga
     8641 ctaggagcaa acaaaatgaa aatacacaca cctatcggct ttttatggtt agatgcagat
     8701 gaatccggat tgactgctgt atcttttcag ccaatttcag aaagcgaatc agcgaatcag
     8761 cgaattttaa cgcgcacaca agaacagttt gaagaatatt ttgcgggaaa aagaaaagaa
     8821 tttgatgttc ctttatctat aaagagaggt acgccttttc agcaaaatgt ctggaaagct
     8881 ttgtcgacca ttccttatgg agaaatccga acgtataaag aagtagccgt tgctgttgat
     8941 agtccgaaag ctgtgcgagc gattgggcag gcaaatcgaa ccaatccatt gccaatcgtt
     9001 attccttgtc atcgagtgat cgggcaaaat ggaaaactga caggatatat gggaaacgca
     9061 atagatgggg ttgaaatcaa acgccaatt
//
LOCUS       DACCVH010000102         8888 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.103, whole genome shotgun sequence.
ACCESSION   DACCVH010000102 DACCVH010000000
VERSION     DACCVH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.103"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            87..1148
                     /locus_tag="IVV98_002548"
     CDS             87..1148
                     /locus_tag="IVV98_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7808140.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            1151..2047
                     /gene="murQ"
                     /locus_tag="IVV98_002549"
     CDS             1151..2047
                     /gene="murQ"
                     /locus_tag="IVV98_002549"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP7808141.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            2061..4043
                     /locus_tag="IVV98_002550"
     CDS             2061..4043
                     /locus_tag="IVV98_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7808142.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(4108..4554)
                     /gene="nrdI"
                     /locus_tag="IVV98_002551"
     CDS             complement(4108..4554)
                     /gene="nrdI"
                     /locus_tag="IVV98_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP7808143.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            4765..6189
                     /locus_tag="IVV98_002552"
     CDS             4765..6189
                     /locus_tag="IVV98_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7808144.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(6370..7143)
                     /locus_tag="IVV98_002553"
     CDS             complement(6370..7143)
                     /locus_tag="IVV98_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7808145.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(7140..8045)
                     /locus_tag="IVV98_002554"
     CDS             complement(7140..8045)
                     /locus_tag="IVV98_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808146.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(8199..8519)
                     /locus_tag="IVV98_002555"
     CDS             complement(8199..8519)
                     /locus_tag="IVV98_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP7808147.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         2803 a         1588 c         1884 g         2613 t
ORIGIN      
        1 ttttaataaa agtattgaaa ttttgtttct ttagatatat actctagtca tagaaatgaa
       61 gacggataca gaaaaagagg gataatatgt ttggcttttc aatatttatg aacgattctt
      121 tgtcagaaga gaagaaacag tatatccgcc aaatggcatc caatggcttt gtcggtattt
      181 tcacttccat gcatatacca gaagatgatg tttcggcata tcaaaagcga ttgatcgaac
      241 taggaagcga agcgaaaaag aataaactag aattgatggt cgatatttca ggagaggcat
      301 tggaacgagc gggtttttca ttagaagatc taacgccttt gaaagcaatt ggtgtaacag
      361 gtttaagaat ggattatcat atttccaatc agcagattgc cgactggtca catcaattga
      421 aaatcagttt gaatgctagc acgatcacgc ctaaagatat cgatgaattg aaagaagcag
      481 aagctgattt ctcacagatt gaagcttggc ataattatta tccacgtccc gaaacagggc
      541 tggacaaaga atggtatcag aaaaaaaatc aatggctcaa aattcaaggt ctccttgtcc
      601 aaggttttgt accaggagat acagagttga gaggcccact atatcaagga ttgccaactt
      661 tggaagaaca tcgagggatc catcctcttg caggcgctct agatctatta gcaagtaaca
      721 cggatattgt ttacatcgga gatgcaggtc tgtcagaaaa cgttcaggag caatttgctt
      781 ctttccaaaa agaacagaca gtcttgctcc atacggaacc tgtagatgaa gaattttacg
      841 aatatatatt agggaagcat acgaatcggc aagacgatgc aagagatgtc atacgaagcg
      901 tagatgcacg ttttcgagag attccgccta tcccagcaag aaatacagct acgcgtatga
      961 aagggtctat tactttagat aacgaaaagt atttgcgcta tatgggtgag atccaattaa
     1021 ccaaatatga tttgccagcg gatgaaaaag tgaatgtagt agctaaagtt atcaaagaag
     1081 agctaccatt gatcaaccaa atcaaagctg gtatgaacta tcaatttata agaaaagaag
     1141 gaagataaaa atgagcaaaa tcaatttaga gaacctaaca acggaacgca gaaaccaaga
     1201 aacttttgga ttagatgaga tgagtatttc tcaagccgtt caactaatga acaaagaaga
     1261 tcagaaagtg gccgctgcgg ttgaaaaaga actgacaagt atcgaaccag tgattgctaa
     1321 cacgattgag tcctttaaaa aaggtggacg tctgatttat atgggagccg gaacaagtgg
     1381 aagactaggt gtgttagatg ctgctgaatg cgtaccgaca ttcggtgtag aaccggaaat
     1441 ggtcataggt ctaattgctg gtggagaaga agcaatgact gtagctgtcg aaggggccga
     1501 agattcttat gagctagggc aagaagatct aatcaagctg aatttgacaa aaaatgatat
     1561 agttattggt atcgcagcta gcggtcgtac accatatgtg atcggtggat tagattacgc
     1621 aaaatcgatc ggtgctgtca caggaacgat ttcttgcaat aaacaagccg aaatcagtaa
     1681 acacgcggat ttcccaatcg aagtcgatgc aggtccagaa tttttgacag gctctactcg
     1741 attgaagtca ggaacagcac aaaaacttat cttgaatatg atttctacta tcagtatgat
     1801 tggtataggt aaagtattca ataacttgat ggtcgatgtc aaaccaacaa atgaaaaact
     1861 aatcgaacgc tcaaaacgaa tcatcatgca agcgacagaa gctgattacg aaacagctga
     1921 aaagtacttt gaagaagcag atcaaaatgt taagctggct atcgtcatga ttttgacaaa
     1981 tagtgataaa gaggaagctc aagcaaaatt agctgaagca aacggatttg taaaagggac
     2041 cttatgaggg ggaaaagacc atggcaaaaa acgaactgac tttggaagaa ctggcaaaac
     2101 aaatttataa aggggcaggc ggcatgggca atgtagaaag cattgtccac tgcatgactc
     2161 gtgtgcgtat gaagatcatc aatgatgatc ttgtaaatgt ctctgaatta aaagcgattc
     2221 caggagtgct tggtgtagta gaagatgaac agcttcaagt catcatcgga cctgggaaag
     2281 tgaacaaagt agcacagcaa atggttgatt tggcaggcgt gaaattagga gaaaaacttt
     2341 cttctgtaag tacagctaca gcaaattcat cagcatctgg aaaagaccgt gtaaacgaac
     2401 gggcacaaga aatgaaagcg gcacaaaaat cgaaacaaaa accatctaaa atcaaatcgg
     2461 tattaaaaga catttctaat atctttgtgc caatgattcc tgcatttgtc ggtactggga
     2521 tcgtggcagg gattgccgca gttttagcaa acttagtcac agccggaaca cttgatgcag
     2581 caacatggca acaatatatc gatgtgatga acatcttgaa aaacgggatg tttagctacc
     2641 tagttatcta tacaggtatc aatgctgcac aagtttttgg tgcaacacca actcttggtg
     2701 gagttatcgg ggccgttgtg atgctgacag ggatgaatcc ggaagcacca ctgaaaaact
     2761 tatttactgg tgaagctctt gcagctggac aaggtgggat cctaggtgtc atcttcgctg
     2821 tttggctatt gtcaatcgtt gagaaaaaac tgcataaagt agtacctgat gcggtagata
     2881 tcatcgttac accaactctt tcattgattg ccatcggtct gattgaaatt ttcttcatca
     2941 tgcctttagc aggtttcatt tctgatggca tggtcggtgg gatcaactgg gtacttggcg
     3001 ttggtggagc atttgccggc ttcgttctag gcacattatt cttgccgatg gttatgttcg
     3061 gactgcatca aattttgact ccaatccatg tgcaaatgat tgatgaaact ggtcgtacgc
     3121 tattgcttcc aattcttgcg atggctggtg caggacaagt gggtgcagca ttggcattat
     3181 ggattcgctg caaaaaagat aaagaattaa cagaaatgat caaaggagct ttaccagtcg
     3241 ggatcctagg aatcggcgaa ccattgattt acggagtaac attacctcta ggacgcccat
     3301 ttattactgc ttgtatcggt ggaggtatcg gcggggcagt gatcggaatg atcggaaatg
     3361 tcggggctat cgctattgga ccttcaggag ccgctttgat cccattgatc tctgacggta
     3421 aatggttagg ctacatcctt ggattattgg cagcttatgc tggtggcttc gttgctacat
     3481 tcttcttcgg tattcctaaa gaccgtttag aaaaagaaga attagcgact gaaacagcca
     3541 cagtaaatga agtgcctgaa aaagtagtac ctcaaacttc agctgaaagt gtgactatcc
     3601 tctcatcagt tgctgacgga acagttgttt ctttagataa agcaagtgat ccagtttttg
     3661 cacaaaagat gatgggtgaa ggctactttg tagaaccaga aaacggacat atctattctc
     3721 cagttactgg ggtagtcagc tctgtcttcc caacgaaaca cgctattggg atcacaacgc
     3781 caaatggttt agaaatcttg cttcatatgg gaatcaacac agttgactta ggcggtacgc
     3841 catttgatgt gaaagtaaca gaagggcagc aagtgacacc tgatacgctt gtagcagaag
     3901 ctgacttaga agcgatcaaa gcagcaggca aagaaacatc catgatcgtc ttggtaacca
     3961 atatggatcg tgtaaaaaac tttgtcttgg aaaaaacagg taaagcaaaa gcaaaagcac
     4021 ctgtgatgga tgtcaaagct taatatgata gaaacaatag aaacgaaaga agaaactgaa
     4081 atctattttt cagcttcttc ttttttatta tttattgttt tctgctaaaa tctgataaat
     4141 tcgtgtcaca tcagatggtg ttccccgtaa ttcataatct gccaagaaag gaaagccaaa
     4201 tgtttgtgca tattgtttgg ctgttagaca atactgatta ttgaagtttt tatttccgct
     4261 accgactaca ccaagacaaa gtttatgatt gtcttcatgt tccagatatt cacgcatcgt
     4321 ttcggtcaag atttctgtat caccgttatc taaaccattt ccgccgtcta aataagtagg
     4381 aacgaaagta aaaaatggtt ctgtttcttt cgtaaaatca ctattttcat ggatttcttt
     4441 taaagtaact tcaggattga caggatcttc tgcatgcatt ttttcagcat attctgctag
     4501 atgtttggca aaggcacgcg tatttcctga aatcgatata tataaaatgt tcatggatca
     4561 tcctccaatt ctttcctttt agtatagcat cttttttaag ttttttggtg gtgtaatttg
     4621 gaaagggact aggcgctttg cttgtataat gagaaaaaag ccggtagaat tatatttcta
     4681 ttaaagtttt tattaattaa gtaaaaataa aaaaggtttg ttatactttt tgataaaagc
     4741 ggttttattt tggaggatgc ttacatggat acagagcaac agaaaaaagg aattggttta
     4801 attccacttg ctgccttagt aattggttca gcgattggag gtggcgtatt tggtattatg
     4861 acggacatct ccggatcggc tggcggccca gctattttca gttgggtact cgtaggaaca
     4921 gcaatgttga tgctctcctt gtcgatcaat aatatcaata aaaaacgtcc agatttaaaa
     4981 ggcgggatct ttagttacgc agaagaaggt tttggccgtt tcgctggttt tatcagcggt
     5041 tggggttact ggctcacatg ctggttaggc aacgtagctt ttgcaacatt gttgatgagc
     5101 gcattaggat atttcttccc agtatttgaa ggtgggcaaa atctggcatc gatcgtgatg
     5161 agtacagtct ttttatgggg atatgcatgg ctagtgaatc ggggagtcga aaatgctagt
     5221 ttcgtcaatg ctatcgtcac attctgtaaa ttagtgccat tatttttatt tattgtagta
     5281 gctatcagca cgttttcgat ccaacaattc attgataact tttctagcga cattatattg
     5341 aatgcgaatg gacagccgat cccgttttcc agtcaagtat tgagttgcat catggtgatg
     5401 ctttgggtat ttgttggtat tgaaggagcc tctgtcgtag gttcacgagc aaaaaaacaa
     5461 tcagatgttg ggaaagcaac gattctaggg atattcggct tgattattat ttacgtcttg
     5521 gtttccatgc ttccatatgg gacaatgacg atgaatcagc tgcaaacgat caaggcgcag
     5581 cctgctatgg gctatgtgtt tgaaatgatg gttggtaaat ggggagcagt cgtgatcaac
     5641 ggcggtttga tcatttcttt agttggtgtt tggctctcat ggacgatctt accgattgaa
     5701 acaatgggaa acatggctga agacggactt ttgcctaaag catggggaaa actcaacaaa
     5761 aatggggcac caacttatgc tatcgtattg acgacgttat gtacgaatgt ctttttactt
     5821 tcattattat tcactgacag tgcttataac tttgcttaca cacttggtac agcagctatt
     5881 ttcttcacgt ggcttttctt aggattgtac caaatgaaac tttcttatca gcggaaagaa
     5941 tgggtccaat ttttagtagg gcttttagca agtgcctttc aagtatgggc tatgctagtc
     6001 gtagccttta atgaagtaat gcttgttctt gttcttttct tgccaggcat ttatttttac
     6061 ctcaaagcac gtaaggagca aaacgagcct gtacaacata tccacttaga taagatttta
     6121 cttataggtg tgacgatggt cggagtgatt gcaatggttt tatttgccac tgggatgctt
     6181 cacgtataga agtataaaag aagtataaag agaggttgtg agcctgtcgt ttattcaaaa
     6241 acatactagg aaaggagctg tgacacaaat gttgtcacag ctcctttttc agaataaacg
     6301 gtgtttaaga gacagccaat cggcaataag gctgaacgtc tctttcacag cctctttttt
     6361 gatgagtcat catacatttt ttcgcttaaa tacgagatat cctaatgcta agaacaaaac
     6421 gatgtaagct aaattaccga atagcatttg attagtagaa agatgagtca attgcttcat
     6481 gatctcttcg tttccaattt ggttttgcag attcaacata ctgatcggat tccatttgat
     6541 ccactcccat ttttggatga gtgcaataag gataccagat atgattgacg aagcaaaata
     6601 aaagacgatt cctgctgaga tggatgcgcc ggaactattg ataaagcaag caatcatcaa
     6661 cactaaactt aaaatcagcc ataaaccgat ataactaccc aaagtataag tgaacaagct
     6721 ttggatcagt gtttgaccag tagaaacctt ctccgtgaag gaaatcgaag ggaaaagaat
     6781 cagtttcatc aacacagtga caataatagc taaaaggtat aaataaacag aataaataac
     6841 taatgtgatc catttgctta ctaatatttc tcctcgagaa tactttcgat aaaggagatt
     6901 tttcaatgta ccatattgtg cttccatcga aatgatcgtg cttgcagctg caatcatgat
     6961 aaagacaatc caagatgtgg cactaaaaag ctgagcagtc atttcaactg gatcaatgat
     7021 cgtcgtgtat tttttggcta gaagtgctgt tcctatgagc aaaacaacta atagaacaga
     7081 taaaacagca gttgactttt tcttgatcaa tttaaataat tcttgtttta caagcaatgt
     7141 catttttctt cttccccctt tactgaatcc agaatttcca atagagaaga ttccaaatca
     7201 ttcgtcagat gctggacgtc tgtcacatgg atattttgtg cagacaatag ctggatcacg
     7261 gttcctaata attcttcgtt ttcttttaaa agcttgattt tatcaggatc ttccaaagta
     7321 tatccagctt ctgtcaagat cgttcgagca gctagatcat ttgttgtaga gataacgatg
     7381 aaatcttgcg ctgtttggtt caattcagcc attgtacatt gtttgatgat ctttccttga
     7441 ttgatcagga tcagctcatc gaccattttt tcaagctcgc tgagtaagtg actggagatc
     7501 aagaaagagg tgccctgagt agccaagtcg gtaatgattt ttcgcacatc tcttgttgct
     7561 tgtggatcca aaccgttcat cggctcatct aaaataacga tagacggatg gttcagtaag
     7621 gcaagagcaa ttcccaattt ttgtttcatt cccaacgagt aggatttcgc ttttttgtga
     7681 atgtactttt ccatcttgag ctgattcacg atagtgtcga tagcagatac atcgttggtt
     7741 tcagagaata acttcagatg atcatagcct gttaagaatg gatagatacc cgggtattcg
     7801 atcaatgctc ctacttgttc caacccttta tgactagagg gagaaatctc attttcacca
     7861 atacagattg ttccatctga gtaatggatc agtcctaaaa tagctttcat gatcgttgtt
     7921 tttccagcgc cattaggacc tactaatcca acgattttgc caggggataa gctaaaactg
     7981 acatcgctga gggcttgttt gtgaccaaag ttcttggata attcttggac cgaaagactt
     8041 ttcaaaaata ttcactcctt ttctatagat agtacaagca tacacctgat gagtggagaa
     8101 gtcgctaggt cattggactt atttcttatt ttttcataaa aaaattgaat attaaataaa
     8161 aaggcttatt ttttctgatc agtacttatt ccaagtgtct agtggccgct agtaatcttg
     8221 atgccaatga tactgatgag tagcatcccc acaaagaacc aagtggaaag attcagctta
     8281 tcatgaaaca agaccacacc aattatgacc gaaccaactg cgccaatccc tgtccagata
     8341 ggataagaga gactcatcgg caaacttttg attgcctttg acaaaaagta aaaactagca
     8401 atcatgccaa tcactgtgta aaaagaataa ttgattttag aaaaaccatc actccatttc
     8461 atcatcgttg accagaatac ttccaaaatt cctgctatga ttaattccat ccatgccata
     8521 cttacattcc tccttaacta taaaaaaata cacaaaaaga ggaaaatcat cccttcaaag
     8581 acctaatgga atgatcatcc tctttatcct acccggtggc agattgtata tctttttctg
     8641 tagtatagca cacctatcca gatatcggca atctcatact ttttagtaaa gtgtaccaag
     8701 cactgacgga tatatcgtta gcggaaaaga agatgaatgc tttgcaattt catagaaaga
     8761 agttgttatt tattaatcat ttaaaaaaaa cagtaactag accttatttc tatatattat
     8821 cgggcaataa attaaaaaaa gctttacctt acaataagta agataatttt tgtgataaaa
     8881 aaataacg
//
LOCUS       DACCVH010000103         8851 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.104, whole genome shotgun sequence.
ACCESSION   DACCVH010000103 DACCVH010000000
VERSION     DACCVH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.104"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            63..1277
                     /locus_tag="IVV98_002556"
                     /pseudo
     CDS             63..1277
                     /locus_tag="IVV98_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1456..1791)
                     /locus_tag="IVV98_002557"
     CDS             complement(1456..1791)
                     /locus_tag="IVV98_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7808148.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1775..2047)
                     /locus_tag="IVV98_002558"
     CDS             complement(1775..2047)
                     /locus_tag="IVV98_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP7808149.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2498..3301)
                     /locus_tag="IVV98_002559"
     CDS             complement(2498..3301)
                     /locus_tag="IVV98_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP7808150.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3279..4403)
                     /locus_tag="IVV98_002560"
     CDS             complement(3279..4403)
                     /locus_tag="IVV98_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808151.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4419..5234)
                     /locus_tag="IVV98_002561"
     CDS             complement(4419..5234)
                     /locus_tag="IVV98_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7808152.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5224..6105)
                     /locus_tag="IVV98_002562"
     CDS             complement(5224..6105)
                     /locus_tag="IVV98_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7808153.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6181..7470)
                     /locus_tag="IVV98_002563"
     CDS             complement(6181..7470)
                     /locus_tag="IVV98_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7808154.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7698..8342)
                     /locus_tag="IVV98_002564"
                     /pseudo
     CDS             complement(7698..8342)
                     /locus_tag="IVV98_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2742 a         1883 c         1410 g         2816 t
ORIGIN      
        1 caaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
       61 ccaagaaaaa gacgttggtc gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa
      121 gttgtggttc tactgtggta gatggaaacg ggaaagcaat tatagtgaaa aatgggaaga
      181 aggaaacgat tgtccgtttt gaacaataca atcatatgcc tttggttacg cgcctaaaaa
      241 agcaacgcta tacctgtaaa aactgtcgta cccattggac ggctcaaagt tattttgtcc
      301 gactcagcca ttcaatcgca gatcatgttc gatataaaat tgcttcttta ctgactgaaa
      361 aagtatcttt gtcttttatt gcgaaaagtt gtcaggtatc tttgactacc gttactcgta
      421 cattgaaaga gtttaaaagc tatttaccaa agccttctaa gaagattctc cccagagtat
      481 tgatggttga tgaatttcgt tcgcacgctt ccatagaaga taaaatgagc tttatttgcg
      541 cagatggtga aacaggaaac ttaattgctg tcttgcctac gcgtaaatta cctcgattaa
      601 caagctattt cttaggctgc accaatccag aagaagtaga attcttagtc acagacatga
      661 acgccgctta cttccagctt accaaacgtg ttctgccaaa tgcgaaagta gtgattgatc
      721 ggtttcatat tgtcaaacac atgaatcagg cactcaatga gttgcgtatc cgtgaaatga
      781 atgagcttcg taaagcagga cagaaaagtc aggcagaaaa actgaaaaag aactggcgct
      841 ttctgctaaa aaatcgtgca agcatcaacc attatgagta caaaacatgg aaaagtttcc
      901 gagcaccaaa atacccattt ctcactgaag caatgatgat tgatcgattg cttgagtttt
      961 ctgcgcctct aaaggaggcg tatccctttt ttcatgaatt agtcgaagcc tttcgagaca
     1021 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacggct
     1081 ttcgggagaa gcttcaaaac cttctgacct atgaagaagg tatcaccagc gcaatgatct
     1141 atccttattc caatggaaaa attgaagcga agaataccca cataaagaca atgaaacgag
     1201 tatcctacgg atttaaatca ttcgagaaca tgagaattag aatctttttg atcaatcaat
     1261 taatcaatgt aagataacaa aaaatctgaa ccagaatgtg gttcattctg acccggattt
     1321 gattttgcac aactcatcag tccttattga caaagagcca aaaatctgag ccagaatgag
     1381 gttcattctg acccagattt gattttgtac aacccatcag tccttattga caaagagccc
     1441 ttctttttag tattattata attcttccat gcgttcttcc agtcgctgta aatcgcttgg
     1501 acttaattcc ccaatttttt tccatttgac ctttttgttg tttttgggta attcgtttag
     1561 agttcctacg tcaatccaag attctttttt tagtcctgcc tgtttccaat cccttatttc
     1621 aacgtatttc agctttattt tatcggattt agtatgatat tttgaagtaa ttgacagaaa
     1681 cgaaattgtg tccagtccat tttttagaat atagacaggc cggcgtttac cgccctctgc
     1741 agctgtgaaa gcaacgtaga cggttgctat atcattagta ttcatcttca ttgaaccatt
     1801 cttcaatttt ttcgtcagtg tctagttttt ggacaggcaa tttttccgct aatctttgaa
     1861 tattatggat tcgtttactt ttttccgaca attcaataga aaatgggatt tttccttgct
     1921 caacaatttg cttataaaaa acggtgacgg ctgttttggg gctcatgcct agttcatcaa
     1981 taatgctttc tgcttcattt ttcaattttt cgtccataga aatttgtaac ttagccattt
     2041 tctccacctc tttctgacaa acacattata tcacggaaag agttcaaatg gaattaatac
     2101 aactactttt gaactccttg aaatgcagtg tatttatcta aatataagga aaggatatag
     2161 tgctaaatgg ccttgataga tagaaaagtt tcaaaatccg ccacagcgat aattgaagcg
     2221 aacactcaac gacacacaga acaggaaaag actcctaaaa gaaccaaatt aactaggacg
     2281 tgtctgaaaa ctccacaaag atgtggtatg ctctggtaaa aaacgaatgg cacaaccacg
     2341 aagaccgata tggttcttgg aaaactttct ccaccctttt tgtaattgga gggatagtgg
     2401 tttattgata gcgattttcc aagttcttca agtggaacca gacattgagc accacggcta
     2461 aaaagtgaat gaagtcttta tttttaatca ataattttta atgattacca gtaattggtt
     2521 ttttcatgcg ccctatttct atttgatgtg gagttaaata atgctgataa gtaaaaattt
     2581 ttccgtcaat taaactgcca ctagtgaatc ctgttctatt ggtaaaaaga gaatagtctg
     2641 ggtattcatc tacaccaaat gataaagatt cagccataaa ctgtttttta ccagcaaatt
     2701 cagcactgct accttgatgg atatgtccta caaaaatacc taaaatatca ctttcggcaa
     2761 tcaattcagc aaaaccttcc ggaacttcag ttacaataga tggatcttcc cacgacaatg
     2821 gatgatgaac caataaaatc gttccctttt cagcaggtgt acccaaccac tcttgtaatt
     2881 gaatcatctg tcctatcgat atttttcctt cgtgctgggt atcttgagca gaatccaagg
     2941 aaataattcg taacccattt tgattcgtac aatggatata ctctcccgtt tcattgcttt
     3001 caacactcat tccttcaaag aaaacactgc gacgatcatg attcccacga caaaaatagt
     3061 aaggtgtggt tgggaaatat tgatccaaca ttttccgtaa gacttgataa tcagaaatcc
     3121 ccccttcatg tactaaatca cctgttaata gaataaaatc gtacactgtt aacgagagtt
     3181 cttgtaacaa tttttccaat gccaactgtg gatttttaat tgttggaaat agttcagcag
     3241 taaacaagtt agtttgatag ttttctctaa aatggatatc agagagatgc aaaaagcgca
     3301 tggctattcc ctctttcttc aataaaataa tcaggatatc ctaaattttc ttgcgtctga
     3361 taatcaaaaa aatgcattct ttcaggttct atgcggagat tgactgcatc accaatctgc
     3421 caagtaggtt tttcattaag gacaatcatt tctataccat cgactttaac ggtgtacgca
     3481 taactttgac ctaatagctc acgatacttc acttgaccgt gtaaatcgct tgtttctttt
     3541 gaaaaggtta cgtgttctgg tcttatgcct aaatacaatg agccactaac ctgaagaagt
     3601 tgtttttgcc aagctggatt caatgttaaa aattgactgg ctacctttaa tgttccttga
     3661 tcataagtaa ctggcataat attcatgcct ggcgaaccaa taaaatttgc agtaaaagta
     3721 tttttaggtt tcgtataaac atttttcggc gtatcaatca tctgaattct accttcattc
     3781 aataaaacaa tccggtcagc taacgtcatc gcttcaattt gatcatgagt gacgtagaca
     3841 aaagtttgtt tataacgttg atgaattttt accaattctt ttcgtgcatc caatcgtaaa
     3901 cgcacatcca aatttgataa cggttcatct aataaaaaat aattactccg tttaaccacc
     3961 gcacgagcca atgctacacg ctgccgttgc cctcctgaca aatctttagg aagtcgatct
     4021 tggtatggcg ttaaacctaa catcttcaaa gcttcttcca aacggtgctg aatgtcagct
     4081 gtcttaattt tattcgccct taatgcaaaa ataatattct cctttacagt catgtgagga
     4141 tataaagcat aattttgaaa aaccattgcg atctctcgtt ctccacaagg tagcttattt
     4201 gctagttgtg tacctaaaaa aagctctcca ctcgtaattt tttccaaacc agcaatcatt
     4261 ctcagcaaag tagattttcc tgaaccagat ggtcccagta acacaattcg ttctccagcg
     4321 gccacagcta aatcaatttc ttttaaaatg gtatgttctc catatttttt tccgatattt
     4381 cttaattcaa gcgtttctcc catgatttgt cctccaattt atttaatacc tgcagaaaca
     4441 aaagtcccga taatatattt ttgaaaaatt gcatacaaga ctaacggtac aaacattgta
     4501 attaaactaa tcgccattgc tacggtaaaa tttgtcccac cttcagaact aatataggtc
     4561 tgcatcgcca acggcaaagt ataattatct actgtccgta aaattaatac cggccaaaca
     4621 tactcattcc aagaggtaat aaaaaaccaa ataccggtag aagtaatcgc atgtctagta
     4681 agaggaaaaa caattttact catgacggtt gtttgtttga tgttatccaa tgccgccaca
     4741 tctagaaggc tcactggaat ttcccgcatt gtttgcgtca ataaaaaaat gcccatcgca
     4801 tcagcaaatt gtggtattat cacaccccaa gtagtatcaa ttaaattaag ttttgcaatc
     4861 aacaaataat taggaatcat cgcaacagta aaaggaatga acatcgtacc aatgatgata
     4921 aagtaccaga ttttcttccc tttgattcgg caataagtaa aactatatgc cgcaaaaaaa
     4981 gctacgccta acttaacaac cgttataatt gtagcaataa aaaaagtatt tctcgtaatt
     5041 ttgataattg gaagattttc gaacaaatag caaaaatttt ccaaggtaaa cggctgtggt
     5101 atcaaactag taatcgtctg ataggcatct ttcaatggct taaaagaatt ggccataata
     5161 aacaataatg gatagataat aatgattatg atgaacataa ataagagatg tggcaaccag
     5221 cgtttaattt tcatagtaaa cccccttttc cacaaattta aatattaccc ctaagaaaac
     5281 agcaaatatt aataaagtta aaactgaaat tgctgaagat tctccgactt tatacatttc
     5341 aaaagccttt tgataagcat aatagatcac gtttgcacta ccattattcg gtccaccacg
     5401 agtgatgatc ttaatcggag taaacacata ctgcagacct tgaacaatgg tcatcaccaa
     5461 taaatatagt cctgtcgaac tactcatagg caacacaatt gtaaaaaaaa tgcgccagat
     5521 gggtacacga tccaacttag ctgcttcgat catctcttga tcaattccca caattgctgc
     5581 aaaaatgaca atgaaattat aaccaaaaac tttccaagca gtaatacctg caatcacagc
     5641 aattacccaa ccttgtaaat tcatccacat aggcagtctt aaaccaaaat ttcccaacaa
     5701 gacagcaatt ggtcccgata ccggatttaa tatccatgta aaaaccatcc ccgccactac
     5761 caaagaaatc acagctggaa taaaaaataa tggtttatac aaattctgcc ctttttctat
     5821 aactattcct aataaaaagg atgtaatata tgggaacaca cagctcagca agacaaatag
     5881 aacggtatag gacaaagtat tcttcaacac tttatgaaag actggatcag tcagcacctt
     5941 tacatagttg gcaaagccaa caaattcttt agtgggggcc accatattcc agtcaaaaaa
     6001 actcaaatag atcgtataaa tcaatggata aaaaacaaac acgcccaaca aaataattgc
     6061 tggcgccaga tacaaataac ctacatagcg cttcatttcc gacagcctcc tcatccttat
     6121 gtcaaaagca gacgaccttg tttttccttt cttacaggcg ctgtcgtctg cttgctttgc
     6181 ttatttgagt aactcattaa tttccttttg agtagctttc atcgtttcat tgacggaatt
     6241 acctgataaa attttatccc gcatatccaa caatttttgt tcagcttcta atccagcatc
     6301 tccaggaaat gaactccaac tgaccatctt atccatctga tcaattgctg gtatcatcat
     6361 ctgattttca gctaagaaag cttttaatcc attttgggcg tctgcaacat ctttacgtgg
     6421 tggtaaataa ccagtacctt ctgtccattt agctaaagat tcaacactat aaagatattt
     6481 taagaaatcc caagttgctt cctttttctt atccgtttgt gatgtaacag ctaacattgc
     6541 gccaccagca ggtagtttaa cttttttccc ttcccaactt ggtgactcaa ctgctttagc
     6601 agtaaaagta ctattttttt gaatgttgtc cctttgagca atagtggtat agaccatcgc
     6661 gacgttacca tcaataaagc tttgcacacc ttgttcccac gtagtgtgta atgccgtctg
     6721 gtcttttacc atcctttgat ataattcata agcagcgata ccatctttag aagcaaaggt
     6781 agctttgcca tcttttatta cacttgcccc attactttct aaaattgctt gttgtgccca
     6841 attatcagca ggttcttgaa tatacacgcc atactttcca gttttttctt ttattatctt
     6901 agaaaaagtt tgaacttctt cccaagtttt tggaccattt tcatccaagc ccgctgcttt
     6961 taatatatct tgatttaaat ataaaaccgg attactaatg gagtaaggaa tacccacttg
     7021 tttaccatct ttttcagaca gtgccatgat attgtctaaa aaatgatctt taaaataatc
     7081 agcattatcc ggatccactt cttctactaa agattgagga ttagtatatt tgaaattttc
     7141 tgcaaaataa tctttaaaag cccatcccac ttgtactacg tccggtattt ctttggaggc
     7201 aacagaagct tgtaaatttt gcatcaagcc tttatacata tcaggattat attttgctac
     7261 aaccttcact ttgtcttgag attgattgta tttatctact aattcattca ctgtttttcc
     7321 acctagggta tccgcattaa catgccaata ctctatcgtt acacgaccct ccgatttttt
     7381 tgttgtcttg gtattcccac taccacaagc tgccaaagag atgacactta aaacagacac
     7441 aacccctata acaagatttt tctttaacat aacattaact tcctcctaat ttctttatgg
     7501 ccatttttct aatcaagaaa tattatgaac taccaatgta aatttctagt taattttctg
     7561 taaataattc gaaatttgtg catttcgggg tacagggtca ctggacatat ccatcaagct
     7621 aagaataaag cccccatatg gtcatgtatc ccatctccaa atctcttaac tcctctgttt
     7681 tgattataaa atagtttatt ctgtgctcct ttcttccata aataggccca tgcacaacgt
     7741 gaggttatat tataaacacc acagcgcgca aggtactcaa tcgtttctag ttcattgact
     7801 gtccatacag aaaatgtcaa tcctagctgc tgccccactt cacgggccaa cttagttaac
     7861 catccttcat gaatattgac gatttgaacg ctttgatagg ctaatttctg taaggtatcg
     7921 atcaaatctg cttcggtaat atccccaagt tttttccctt cgaactgatt ttcaatatta
     7981 taaaatatat gctttcccca aatcgcagcc caagataatt gtacatagcc actaagaaca
     8041 atttgtggcc agatttgata ggtttgtgcc agcgaaaaaa cggccatttc caatccctct
     8101 tcttttaaat cacagttaat ggtcatggtt gccttctcat tggccactgc ttgaaacacc
     8161 tgctcaaggg ttaccgaatc tgggacaact tcttacctgt catgggctag tattagcgta
     8221 ccatctgttt gctgacgcac atctacttca aaacaaagct ggcgatccaa acaaaagcga
     8281 agaaatgccc agctattctc ctccgtattg tcactaccag agtgtgcagt gatcatggtc
     8341 attttgaccc ctcctttaat tccgtgattt tctcccacac gtccactata ccgatgaagc
     8401 gttaatttct tgttaatttc ttgtaaattc cctgcgtttt ttcagtaaac tagttgtaaa
     8461 tcttgcatgc tccttcctac gaactcatga atcgtcgatt ttgcccttct agctagtttc
     8521 accaattaag tagttctaca ttccccgctt ttaacctact acaccttttt ttgttttcag
     8581 ctattccttc ttcttgctga aagtccttga ggttctttct tacaggatac catcaaggtg
     8641 ttcaatggct tattcccatt gaatgaccga gacttactat cagatttctg ctcgttgaac
     8701 caagtctttg atacaggatt tcttccgtca tcttctcaca aataccacct tgcgtttctc
     8761 tagcgattgg tcgatgtgca ccctcccagt ggactgtcac tacccctttt tgctatgcct
     8821 agcccacaaa aaaagctgtc ctcacagaca g
//
LOCUS       DACCVH010000104         8822 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.105, whole genome shotgun sequence.
ACCESSION   DACCVH010000104 DACCVH010000000
VERSION     DACCVH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.105"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            21..1361
                     /locus_tag="IVV98_002565"
     CDS             21..1361
                     /locus_tag="IVV98_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7808155.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1579..2022
                     /locus_tag="IVV98_002566"
     CDS             1579..2022
                     /locus_tag="IVV98_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP7808156.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2526..3944)
                     /gene="nhaC"
                     /locus_tag="IVV98_002567"
     CDS             complement(2526..3944)
                     /gene="nhaC"
                     /locus_tag="IVV98_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP7808157.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4347..5570)
                     /locus_tag="IVV98_002568"
     CDS             complement(4347..5570)
                     /locus_tag="IVV98_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP7808158.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5601..6440)
                     /locus_tag="IVV98_002569"
     CDS             complement(5601..6440)
                     /locus_tag="IVV98_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP7808159.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6457..7137)
                     /locus_tag="IVV98_002570"
     CDS             complement(6457..7137)
                     /locus_tag="IVV98_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808160.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7139..8212)
                     /locus_tag="IVV98_002571"
     CDS             complement(7139..8212)
                     /locus_tag="IVV98_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808161.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
BASE COUNT         2524 a         1811 c         1610 g         2877 t
ORIGIN      
        1 ttaaaagaaa gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac
       61 atatcaccat gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg
      121 aagcgattgg gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt
      181 tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg
      241 gattatctgg tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg
      301 tctactggtc tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt
      361 tgcagttgtg gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa
      421 ctacgatcat caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt
      481 ttgctaaaat cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc
      541 aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta
      601 ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg
      661 gttctgaact gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta
      721 aagcaatcaa aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc
      781 ttttgattct ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg
      841 tatttgaaaa aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg
      901 ctttgttctc atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt
      961 tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc
     1021 aacgtgctgt tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg
     1081 tcggtgacaa attatttggc tatctggcag gttccctttc gtatacagta ttattgatct
     1141 ggatcattat cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata
     1201 aaggaatcag cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca
     1261 cgaactccat tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt
     1321 atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat
     1381 tttatttatg tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg
     1441 caactccttt ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc
     1501 tctgtgcaaa ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa
     1561 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca
     1621 acggtagtta tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc
     1681 agtcgtacac gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg
     1741 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt
     1801 cttcttgttt ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca
     1861 gcttggatga aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct
     1921 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
     1981 gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata
     2041 aaaaaagagg atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga
     2101 acgccgtgaa taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
     2161 caaaaatagc ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt
     2221 gaacaccgtt tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa
     2281 atggaaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
     2341 tgaacaccgt ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat
     2401 tttgtgaaat ggctttccac atttttgtat aaatttggct taataccgag aaactggctt
     2461 ttgaataccg tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta
     2521 tgtttttatt gttctaattg cgctgtcttg cttactgctt cttgcggttt cacaaatttt
     2581 tttgagattc cccaacctgt gaaggcactg accatcgaaa acacaggaga aagcaaactg
     2641 aaaaatacga atggcaagta agtgagtgta ggaataccaa atgtacttgc tacgaaactt
     2701 ccggcaattc cccaaggcac taagtagttg attactgttc caccatcttc tagcgttcta
     2761 cctaatacag ttggatcaaa tcctgctttt tcataagttt ctttaaatgc attaccaggc
     2821 agaataacag ataggaattg ttcaccaata aaaatattta ctccgatact tgtcatcaat
     2881 gttgtaaaaa tcaaatttgg tgtgttcgtc atctttcttg atactcgttc catcacggtt
     2941 gagatcaagc caaattcgat caacaatcca cctaatgaca aagttagaat aatcaatgac
     3001 acagtaggca tcatactttc gattcctccg cggctaagca gtgaatcgat ttgttggttt
     3061 ccagtatttg aaacaaaccc tgattcgatg accccagcca acttcgttaa ggaagtttgt
     3121 gggttttgaa taaaaatcat tcctactgct acagcgatat tcaacaaaat cgttaaaatt
     3181 gccggcacct ttttccatgc acacagtaac attaaaaata aaggaatcag tgaccagatt
     3241 gaaatagtaa agtttgcttc tagaacatca gtcacttcac gaatagatga aagacttgcg
     3301 gctttacttg tgtgtcctaa aatcatgaat aaaaagaaag aaacaacaaa tgccgggaca
     3361 gttgaccaca tcatatgctt gatgtgtttg aacaaatcgg catcaacaat agctgctgct
     3421 agatttgttg attcggataa tggagacatc ttatctccaa aaacggcacc tgaaacaata
     3481 gctccaacaa ccagcgctgg atttaagcct agtgttgtcc caataccgaa aaatgcaatc
     3541 ccaatcgttg acataacagt aaaggcactc cctacagcgc tacctacgat tgcacacaca
     3601 acaaatacag aagggacaaa ccactggaca ctgatcaatt tgaacccaat gaccattaga
     3661 gttggaatga tccctgcttg tatccataca gcaatcaatg aaccgactaa aataaaaata
     3721 aagattggga tgattcctgg tttgatgcca ttgatgattc cttcgtgcag ccaatctgtc
     3781 gggtatcttt ttatcactgc atacaacatg accattccga tcgctgctaa gatcgtgata
     3841 ttaggtgaga cctttaatcc gacaacgcca atcgcaatgc ctaaaacaat aaccattaat
     3901 acaagtgttg cttctaaaaa acttggtgtt cctttttttc ccatgataat ctctcctttt
     3961 ttagttgttc ttatgttcta aaaaagttaa gatatcggat tactccgccg caattcatcc
     4021 gcgattcctc ctttataaaa ataaaaagac ctgttttaaa ctaaggacga atgactccgc
     4081 ggtaccacct taattaaaaa cagatctgtt tttcactttc aaacttttat tcaaatgtat
     4141 ggactttcca tgtaattcgt caattaggct tgatcggttc acagcgacca ccgactttct
     4201 gaacaaaaca cctaaccgct actgcgtgaa aagttgactt gtacgaagtt taccttccat
     4261 aagatcattt gtcaatgaaa aagaaaatat tttttcattt ttctgaaaat tatttttata
     4321 actttcacac acaagtttat tttttactag aaagtagcgc cctcttgttt ttttcttgct
     4381 actatttctt gatgttcttg cttgattctt tctaatagct ttggctcttt caacagatca
     4441 agagctgtat tggcgagtag ttctgctgca atcgcaatag aagcaaggcc tttgtcactt
     4501 ttagcagcag ctttgaattc ttctgtgtgt ccggcaatat atgtctcaga gattgctacc
     4561 gtaggctgga ttgttggtat gacttggctg acatttccta catcagaaga accgagactt
     4621 gttctttgtt ccgtttctat ttcttcatct ggaacacctg cttcttttgc atgctggaag
     4681 aataagtcat caaaagaagg agtaacgatg acatcatcaa ctgcattttg gaacaatcca
     4741 aactcaaaag tcgtgcccgt acttatcgca gcacctcgta cgatattttc cactttttca
     4801 tatactttat ctaatgtttg ccgatttcct gcacgtaaat agaaacgtcc agcagcgtaa
     4861 tctggaatga cgttggcagc tactcctccg tctgtaatga tcccatggat attgacatct
     4921 tttggcaatt gcaagcgtag agcgttgatt ccattaaaca cttggatcaa tgcttccaaa
     4981 gcatttactc ctttttcagg tgctgctgct gcatgggaag cgacaccgta aaatttgatg
     5041 tcgactggat cattcgctaa agattctgtc gttttcccat aacgaaaagc tggatggacg
     5101 cataacgcta catcgacatc ctcaaaaaaa ccttctcgaa caaagctgcc tttagctgat
     5161 ccgttctcgc ccccttcttc ccctggggtg ccatatacac ggatttctcc accagtttca
     5221 tcaatgaatt gcttcactat gctggcggct aatacggagt aagtaccaaa caaattatgc
     5281 ccgcatgcat gaccaatacc tggtaaagca tcgaattctg ccaaaaaggc aattgtggga
     5341 ccgggtttat tggaaatata acgtgcatca aaggctgttc ggtgtccagc tacttctttt
     5401 tctacccaaa acctttcttt ttctaattgt ttaatcaacg ctgctgagga ataaaactca
     5461 tagttactta cttcaggatg ttcgtggata tctagagcaa gtgcttgata ttctggtaaa
     5521 cgatattgga ttagatcctt caattggttt gttgagattg ttgttgtcat aaaaaattcc
     5581 tcctatgcta gtcatttttc ttattttctc ccgaatgttt cccatgcagg cacgcttgat
     5641 ccttttgatg ttttctcgat tactttgact gtgtcttctg tttgataagc gtctactatt
     5701 ttttgatacg ttttattgtt ttcatcttct tttcttgcaa cgatgatatt cacataagga
     5761 cgtgcatggt catccactgg ttctaagaag atggcatcag aagcaggatt aaatccagca
     5821 tctacagcta caccgctatt gatcactgaa atgtctacat ctgacaaagc acgtgctgtt
     5881 tgggaagcat ctaattcaga aatgtctaga ttttttctat tctcggtaat atcagaaaca
     5941 gtgggcgctt gtccttttgc cttatccact ttgatcaatc cagcagtttg caataacaga
     6001 agagctctgc cgccatttgt aacatcatta gggattgcta cttttgctcc gtctttgata
     6061 tcagctacat ccttcaaagt gttagaataa attcccagcg gtgcattgac agtatttccg
     6121 atcgatacta aatcagttcc gtgttcttta ttgtaattgt ctaaaaagaa ttgatgttgg
     6181 aaagaattca aatcaatcga tccatctgct aaagccacat ttggttgatt gtaatctgta
     6241 aatttcacgt attccaaatt aatgttctcc tttttcaaac ggtctttcac gttgtcccat
     6301 acatctgtat cttctccaat aatccctagt tttacgatag tttctttttt gtcagttgta
     6361 tctgcttttc cttggctaca ccctgccaac caaataattg ctacaaatgt aatgactaca
     6421 aaacgaataa tttttttcat tttttctcct ccactttcaa tgtgtaattt ttttaatcag
     6481 ttgattactg ataaattgac ttaaaaaaac taagattaga atcaataatg tagccacaat
     6541 cgttacatct gtttggaatc gattataccc tctcgatata gcaagattcc ctaatccgcc
     6601 tgcacctact gctccagcca tggtagtcag tccgatcacg ttgatgatag tcaacgccga
     6661 gacccgaatg ataccaggca aaccttctaa caaatacaca cgtaaaatga taccgattgg
     6721 actggttccc atcgcttctg ccgcttcgat caccccagga tcaacttcta gcagtgcgtt
     6781 ctcgatttga cgagcaaaaa acggaacaac tccaaaaatc aatggcacta aagctgcttt
     6841 cgcaccaatc gtcgttccaa ctaagaaacg agtagtcaat gctaaaagag aaagcaagat
     6901 aatgaaaggg atggaacgaa tgatattgat cagcttatca agtatttcaa atagcagacg
     6961 gttagctagt aatccattag ggcgtgtcac tactaacgtc acacctaaga tgattccaat
     7021 catcccgcca atgaatgctg tccaaaaaga catatatagt gtttgcttcg tcgcttcgac
     7081 aaattcatcc ggaatcaaat aaacattggg caaatatgtt ttaaagaaat cagtcatttt
     7141 atcttcctcc ttcgatcact ttgatacgac tatctaaatc gtttttttgt aaaatattta
     7201 tttttacacc agatttgatc aaataatcca atgctttttt ccgctgtttg gtttctccag
     7261 ctaaagtaac gatcaaactc cctaacggcg tttcttgtaa taactctaca ttgccatata
     7321 aaatattcgc tgttacttga tatttgctgt acagatgagc gattagaggt tcgttcgtct
     7381 gatttccaat ataacttaat tccaccagcc atttattggc gatctgatcg gcaaaagcag
     7441 aatgggcaat gatcgtttct aatgcttggt caagatgagt agctgttcga ataaaatctt
     7501 tggtcaattc ttcttcagga ttgctgaaga tctggatgct gctacctttt tcaacgattc
     7561 ttccatcttc cataaccgct accttgttgc agatttcttt gacaacttgc atctcatgag
     7621 tgatcaggac gattgttaaa cctaactggc gattcaattt ttttaacaat gcaaggatct
     7681 gaagggtcgt tttcggatca agtgcactgg ttgcttcatc acataataat accttaggtt
     7741 cattcgccaa agctcgtgcg attgctactc gttgtttttg tccccccgac agttgtttag
     7801 gataagcaga tgctttttct tccaaaccga caagttccag tagttcattc actttttgac
     7861 gacgttcctg tttcgatttt ccagaatact ttaaagaaaa atcaacgttg tcaaaaatag
     7921 ttcggctttc cattagattg aaatgctgaa agatcatacc gatggccttt ctttcttttc
     7981 gcaattcttt gggagagagc tgactcagat tcgtctgatt gacaatgact tctcctgctg
     8041 ttggtttctg cagcaaattc atcacacgaa ctaacgtact tttccctgca cctgagtaac
     8101 cgacgattcc ataaacatcg cctttttcaa tcgttaaatc tacagaatct actgcctgta
     8161 tctctttttc tttttgtttg aaacatacag aaacatctcg caattcaatc attaaaattc
     8221 ctccttatct aaaaaaagcg tcctcaagaa aatgaaaatg tcattttctt gaggacgctt
     8281 ttttgcgtgt taccacctca tgttcaagct gtgttcacac acaactcctc ttcaagtacg
     8341 atcatactct agcaagatat cggtcgcagc cgtcatcgcc ttacatctat gctcgggatg
     8401 aattgctcga tggccatttt ccaatagtcg ttccttgctt cttctcagct accgaagctc
     8461 tctgtcaaag gttcttctat cgtacttacc atttcaatgc aaataatatt caaaaaaaaa
     8521 gtccttttac taacataaac tatgtcagta aaaggacgac gtatcgcggt accacctttt
     8581 ttcggaagtt tccttccctc aagcccaaca tctcaaaaag agagattggc gttcgtttta
     8641 acggtcgaac agttccgaat ttgcctactt atcgacaaat tattctccaa ggccattttc
     8701 agcttttctt acttgactct tctcaccagc cagagcctct ctgcaaagtt tccaaactta
     8761 ctttcctttt caacgaaatc gatattttgt tgttgggatt aatctacatg aggaaaactg
     8821 aa
//
LOCUS       DACCVH010000105         8657 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.106, whole genome shotgun sequence.
ACCESSION   DACCVH010000105 DACCVH010000000
VERSION     DACCVH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.106"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            17..1024
                     /locus_tag="IVV98_002572"
     CDS             17..1024
                     /locus_tag="IVV98_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7808162.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1036..2040
                     /gene="neuB"
                     /locus_tag="IVV98_002573"
     CDS             1036..2040
                     /gene="neuB"
                     /locus_tag="IVV98_002573"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAP7808163.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2037..3185
                     /gene="neuC"
                     /locus_tag="IVV98_002574"
     CDS             2037..3185
                     /gene="neuC"
                     /locus_tag="IVV98_002574"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP7808164.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3158..3835
                     /locus_tag="IVV98_002575"
     CDS             3158..3835
                     /locus_tag="IVV98_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP7808165.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3825..4967
                     /locus_tag="IVV98_002576"
     CDS             3825..4967
                     /locus_tag="IVV98_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP7808166.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            4980..5957
                     /locus_tag="IVV98_002577"
     CDS             4980..5957
                     /locus_tag="IVV98_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7808167.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            5957..6865
                     /locus_tag="IVV98_002578"
     CDS             5957..6865
                     /locus_tag="IVV98_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP7808168.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            6866..7618
                     /locus_tag="IVV98_002579"
     CDS             6866..7618
                     /locus_tag="IVV98_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP7808169.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            7623..8570
                     /locus_tag="IVV98_002580"
     CDS             7623..8570
                     /locus_tag="IVV98_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP7808170.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         3185 a         1097 c         1664 g         2711 t
ORIGIN      
        1 ataggaggag atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc
       61 cattggaagt gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta
      121 tagtagaggt gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt
      181 gagattttta attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt
      241 ggatattatt tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat
      301 ggaagctgta aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa
      361 taatgtaaaa cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat
      421 gggtgcgaca aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa
      481 aacagaaaca atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt
      541 tattcctctt tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga
      601 tatgacacga tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat
      661 gaattcaaaa tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt
      721 agctcaatca ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat
      781 aaaagttgta ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga
      841 aattgaacgc tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac
      901 tgacgaactg tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac
      961 agaattaatg agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg
     1021 gtaaggagtt ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat
     1081 aatggaagtc tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac
     1141 gcggttaaat ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca
     1201 aaatatcaga aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta
     1261 gaattatctc aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat
     1321 tttttgtcta ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa
     1381 ggatttaaaa ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg
     1441 tatgggttgc cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct
     1501 gtagattgtt tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct
     1561 agttctgaag atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc
     1621 gttgggtact ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt
     1681 gctaaggtaa ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa
     1741 gcttctttag atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata
     1801 tttttaggtg atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca
     1861 agaaaaagcc tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct
     1921 cttacaataa aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc
     1981 aaaaaagtta aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga
     2041 aaaaaatact tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg
     2101 agaatttact acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc
     2161 ataaatatgg atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag
     2221 ttcaaagttt gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga
     2281 taaatggttt cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg
     2341 atagaggaga aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac
     2401 atattcacgg aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga
     2461 aaatagcatc tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg
     2521 gggaagattc ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata
     2581 atagattacc tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa
     2641 aatacgtttt gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa
     2701 ttttagcttt gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta
     2761 atagtgatgc tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata
     2821 ttatttatat tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat
     2881 ttatgatcgg aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa
     2941 taaatttagg aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc
     3001 taaatgaaaa tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa
     3061 gcttgaaaaa tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa
     3121 cattgaatca aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt
     3181 attaaaatat actagtgatc catacattat tattggggct ggcggacacg caaaagtcat
     3241 tattgaaacc ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa
     3301 taaaatgcaa gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag
     3361 caaaaaaaaa atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat
     3421 tataaaaaaa ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat
     3481 agtggcaaaa gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa
     3541 cccagatgct gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga
     3601 ttgtagaatt aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca
     3661 tgtaggtgta ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg
     3721 atcttggtgt atgataggcg cagggagcac tattgttaag gatattccct cacattcctt
     3781 agcttatggc aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt
     3841 tattatcaag tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag
     3901 ataattggat agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat
     3961 atactggttc taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg
     4021 ccttaagact gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta
     4081 tagctacagt aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac
     4141 ctaatacatg gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa
     4201 acaaccaatt acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg
     4261 aacgaatttt agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat
     4321 cgttaggttc tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt
     4381 catttaacgg taataagatc atcacaacct caggtggagg agctctagtg tctagtgata
     4441 aaaaatatgt tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt
     4501 atcaacatag cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac
     4561 gtggacaaat ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat
     4621 ataaggaagc tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg
     4681 tgccaaatcg ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag
     4741 ttaacgtaat aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac
     4801 tacatttgca accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg
     4861 tgtcagaaaa gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata
     4921 gtgaacaaga atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta
     4981 tgaacatagg aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag
     5041 aacactttaa tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag
     5101 ttgaaaagga atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg
     5161 aaataaattc agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg
     5221 ctttaaattt agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg
     5281 aaataatcga agtagctaaa aagaaagata gattacttta tctatcttct acatttttga
     5341 agagaaaaga aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc
     5401 aataccatgt aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt
     5461 ttgtttcaaa caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga
     5521 ttatagatac atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc
     5581 ttgatattga ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg
     5641 gaactttaag tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg
     5701 aaaagatttt aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa
     5761 cttctagtat gacagatatt caattgtacg atgaggttat gcatgataat aattattcac
     5821 atactattat tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa
     5881 agaaaatgga accccaatat acttttgaaa aagataagta tattattaac ttaattaacg
     5941 acattgaggt aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag
     6001 acatctaaaa aatctaataa gctatggaaa aaagaattct attaattttg atataacagc
     6061 ttatagtagc agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga
     6121 tttggataca cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac
     6181 actaaatgta attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga
     6241 gagtattgat cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact
     6301 gaggtataaa aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc
     6361 tgtaagagct atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa
     6421 taattattct gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt
     6481 ggattatatt ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata
     6541 ttcgaatctt gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa
     6601 aattatagaa attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt
     6661 tactttagat gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa
     6721 cattgttaaa gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt
     6781 ctttgaaaac gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt
     6841 attgaaaata gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg
     6901 gtctaagggg tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt
     6961 cgctttagca atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg
     7021 tttgaatacg gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa
     7081 aattgtagaa cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg
     7141 tgattcattc ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga
     7201 tttgacttca cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa
     7261 aaatttagat aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa
     7321 tatggtaaaa agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag
     7381 gcaacagaca cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt
     7441 tctaaaaaaa agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta
     7501 tctaatttta gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa
     7561 atttttagaa gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa
     7621 ggatgagctg ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc
     7681 atttaggaga agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa
     7741 atcttgatat gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga
     7801 tggaagagat catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta
     7861 gtgtggcaga ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat
     7921 taatgatttt agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt
     7981 cttcagcggc tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc
     8041 gcccattgac gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt
     8101 gtcatttata tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc
     8161 aaaatccgaa ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac
     8221 aaatcgtagg agaagcaact tcatttacat tatttggtga tggaagccag tctagagact
     8281 ttgtttatat agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac
     8341 tggggaaaca attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg
     8401 caatcaatga aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg
     8461 atatccatga ctctctagca gatattacta agatccagtc aattggctat caaccgaaat
     8521 atggtatttt aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa
     8581 gataagatta gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa
     8641 tcaaatctgg gatagaa
//
LOCUS       DACCVH010000106         8603 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.107, whole genome shotgun sequence.
ACCESSION   DACCVH010000106 DACCVH010000000
VERSION     DACCVH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.107"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="IVV98_002581"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="IVV98_002581"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP7808171.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="IVV98_002582"
     CDS             complement(1098..2201)
                     /locus_tag="IVV98_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP7808172.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /locus_tag="IVV98_002583"
     CDS             complement(2291..3226)
                     /locus_tag="IVV98_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP7808173.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="IVV98_002584"
     CDS             3528..5462
                     /locus_tag="IVV98_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7808174.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="IVV98_002585"
     CDS             5919..6335
                     /locus_tag="IVV98_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP7808175.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="IVV98_002586"
     CDS             6349..6915
                     /locus_tag="IVV98_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP7808176.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="IVV98_002587"
     CDS             6938..7924
                     /locus_tag="IVV98_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP7808177.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8603)
                     /gene="scm"
                     /locus_tag="IVV98_002588"
     CDS             complement(8079..>8603)
                     /gene="scm"
                     /locus_tag="IVV98_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP7808178.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2527 a         1657 c         1752 g         2667 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt cacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacgagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgttgt ggtagatgta
     8521 tccgtactgt cgcttgaagc tgacgtgtcc gtgctatcac ttgtggtaga ggtagtatct
     8581 gtactgtcac ttgaagctga tgt
//
LOCUS       DACCVH010000107         8575 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.108, whole genome shotgun sequence.
ACCESSION   DACCVH010000107 DACCVH010000000
VERSION     DACCVH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.108"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(173..2554)
                     /locus_tag="IVV98_002589"
     CDS             complement(173..2554)
                     /locus_tag="IVV98_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP7808179.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2544..3191)
                     /gene="recU"
                     /locus_tag="IVV98_002590"
     CDS             complement(2544..3191)
                     /gene="recU"
                     /locus_tag="IVV98_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP7808180.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3255..3794
                     /locus_tag="IVV98_002591"
     CDS             3255..3794
                     /locus_tag="IVV98_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP7808181.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3884..4303
                     /gene="gpsB"
                     /locus_tag="IVV98_002592"
     CDS             3884..4303
                     /gene="gpsB"
                     /locus_tag="IVV98_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP7808182.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4325..4692
                     /gene="rnpB"
                     /locus_tag="IVV98_002593"
     ncRNA           4325..4692
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IVV98_002593"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4901..6067
                     /locus_tag="IVV98_002594"
     CDS             4901..6067
                     /locus_tag="IVV98_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP7808183.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6113..7609
                     /locus_tag="IVV98_002595"
     CDS             6113..7609
                     /locus_tag="IVV98_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP7808184.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7690..8373
                     /locus_tag="IVV98_002596"
     CDS             7690..8373
                     /locus_tag="IVV98_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7808185.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         2686 a         1565 c         1824 g         2500 t
ORIGIN      
        1 aaagaaaaat ggattttcta atttttaagc taaatgttag atcacacatg tatatgctgg
       61 atagtcttat aaaaaatcat gtaatacagc ttggtacatg atttttattt gtagctgttt
      121 tttacataga cacaaaaaag aaaccacgct tgtagacgtg gtttcttttt tactatctgt
      181 ttccagaagc tgaggtgctg ctggatggtg tatggtcatt tgcagcatcc gctccgctag
      241 ttgctggctc actggaagaa gcaggaggag cagatgaaga cggtgtcgag ctttcttcgg
      301 atgaagaaga aggaaccgtt gttgaagacg ctggctcgct tgtttctgct gtcgtgcttt
      361 cttttgagga ctcagcagtt gattcgcttt gactagtaga gctagagctt tgagtcgttg
      421 tctctgttgt tgagcttcca ggagtctgga catagctgga agatggaata gttgttgatg
      481 gtgtaattgc attcgatcta gctgtatatt gatctttgta gtacagttca ccgcccacac
      541 gaattaatcc gcttggcatc tcccagtctg tatttgtcac gttagctgaa acatactgca
      601 taagctcgcg ataaacatca gaggctacgt gtgacgattc tgaagtgaca ggcgtcattt
      661 ttttattgta acctgtccac acggaaatcg aataatttgg cgtatagccc gcaaatagga
      721 tatctggata caccccagaa gaaataccaa gttttgcata ctcgtcatct gtgtaattgg
      781 atgttccggt cttaccggct tgatataacc cagcgatttg cgcattcgta ccagttcctt
      841 cagtgatcgt atcttttaaa atgtctgtga tcatataagc tgtttctgga gacatggctg
      901 tttttccatc tggctcataa gtttcttctg ttccgtcttg gaagacgatt ttattaacat
      961 attgaggttt gtaataagtc cctccattgg cgaaagccgc ataggctgct gccattttta
     1021 aggaagaagc tccgtatttt gtcccatctt gttcttccgt attactagag atcgcattcg
     1081 attgatggat cgtactgtat tcgatcccaa gattttttaa gaaagaagcc actttatctg
     1141 aaccgacttc attgaataat ttgactgctg gaacattacg ggataagtaa agtgcttggc
     1201 gtaaagtaat ggtgcccata tattgattat cccagtttcc tacaggagtc gaagtccctt
     1261 catagttata cggtgcgtca gtaatagttt ttccagtaga atatttcaaa tattcaaaag
     1321 ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa atcacgggaa gtattcactg
     1381 ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg tccgccaatc tgggctttta
     1441 ctttcccggt attggtgtcg ataagggtgg aggcaacttg catctcgtcg tctgggtaag
     1501 agacatactg atccgtgttg acgatatcat atagtttctt ttgggcgtcc agatccaaat
     1561 tcgtataaat ctctaaaccg tctgtgtaga cattcttatc tgttttttct tgtacttcat
     1621 tgatgacttc tttgacataa ttatcgacga tcttagtatt gtcatcggat tgagttagtt
     1681 cttgcagacc atccgttacc ggtacattaa cagcttgatc atattctgtt tgagagattt
     1741 tttcgttttg aagcatcgta tacaaaacag tatctcgtct tttcttcgcc tgatctggat
     1801 aaacataagg atcataggcg gaaggggctt gaggcatccc agcaagcaat gctgtttgcg
     1861 gtaaagaaag ttctgataat ttcttaccaa agtacatctc agaagctgtc tccatcccgt
     1921 acaagccgtt tgacatatac actttattta cgtagtaggt caagatctct tgtttcgatt
     1981 ttttttgttc caatcttaca gccatccacg cttcttgggc cttgcgtttc agagtctgat
     2041 cctcggcact ggtggagaag aaggaaagtt tgatcaattg ctgtgtcaaa gtacttccgc
     2101 cttgcagtcc gccagaggta aagttagaga gggcagaacc gatgatccga atagggtcaa
     2161 ccccgatgtg tttataaaaa cggcgatctt ctaccgacac gatcgcatct tctaatgttt
     2221 tcggtaattc attcgcagaa attttttcac gcttttctgc gcctaaatct tcgaatagtt
     2281 cgccatcttg tgtatatagt ttggaagata cggtagcgtc taatttttta tccgtcaatt
     2341 cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc tgctaaaaag aggatacaga
     2401 aaaatgagag tattcctaaa aggatcttga taaataatcc ttttttatgt gttccagagg
     2461 actttccaga acctttgcca gaattcttct tcacactctt tttaggagta ggctgtttct
     2521 gtcgtctaga gcttctagtt tgttcatttg ccattcttgc tttctccttc aatagataat
     2581 gttgataaat agaagtcaac cgcgtccaaa taaggaatcc gcggagaaat accagttttg
     2641 atctctattc ctagttcttc gatcaaagat aaaggtagtg atttgcgtcc tttttccttt
     2701 tgggcgtccc agtaagcaat caaatgaaca ctattcaaat aaaaacagcg cttcaaagac
     2761 gaaaaccata acaagacaaa gcagacccca ttttgttcga ggcatgcttt catatgttcg
     2821 atttgatggg catggaagtt tttaaaggga aaagatgttt tgttcttggt ttcttttgct
     2881 tcaaagtcca agtaaaagcc tcgatagacg ccattatagt ctgtagttga ggcttgggta
     2941 aagtaggctt ccttgatcac agcagcactt ctcttaggat agtctacttt cacgatttgg
     3001 ataggggtag gctttttatg gataaccgcc aacccgcggg aaagataata tttattactt
     3061 tcattgattg cttcttcaaa gcgcatcccc cgattgccga attcagtgat ctgatttctt
     3121 ttttcttgaa ttttttcgac gggagaggca ttcttataat aaggttggcc atttggatag
     3181 cgcaatacca tctttaatca cactcctagg ccacattata gcaaaaaagc ggatagaaag
     3241 aaaaggaatc tgagatggat aagtcaaaag taatctatgt gtctgggtat cgaagtttcg
     3301 aactcggtgt ttttaaagaa aatgatccta aaatccaagt tgttaaaaat gttttaaaaa
     3361 aagaactcca tcagttagca gaagaagggc tggaatgggt acttgtcagt gggaatttgg
     3421 gcgtcgaact atgggctgtg caaatagtag cggaattgaa agaagaatat ccggaactat
     3481 ctcttggtat tttgtatcct ttttctgatt ttggtaataa ctggaatgaa gggaaccaag
     3541 aaaaaaaaca attagcagaa caattagcag attatgtcga agctgttagc catcaaccct
     3601 accaatcacc tagtcagcta aagaatcaca ctcgttttat acttgagcat acagtgggct
     3661 gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa gtattttttt gaagatgcac
     3721 agaattacca agcagatcat ccctacgaaa ttcggctgat cagtatggac gatcttcaaa
     3781 attttagtga ataatcgata ttgtgtttga tttatcaact tttttcctat acaatgaaaa
     3841 aggtagaaat gttattacgt aaatgaaaac tagaggtgta aatatggcga atttggttta
     3901 tagtcctaaa gacattttac aacaagaatt caaaacaaaa atgcgcggct atgatcccgt
     3961 tgaagttgat gaattcttag acaatatcat caaagattat gaaacttaca gcaaagaact
     4021 ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa gtagctcaat tatctaaaac
     4081 tcaaggagca gctcaaacac gcgtgcaaca aacagaggca ccaaagagcg cagcagtgac
     4141 caattttgat atcttaaaac gcttgtcaaa tcttgaacgt gaagtatttg gtaaaaagct
     4201 tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat ccaaataact acacaaatgc
     4261 agacacaagc ttagatgata atgaaaaaac acgtcaattt taatttttga ttaatgaatt
     4321 tgcggttttc gggtaatcgc ggtctgactt gatcaggctg aggaaagtcc atgctcgcac
     4381 aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat aagctaaggt actctttgga
     4441 gtaacggcag gaaaacaagc taaggcttcg gctatgctta agtatccttg aaagtgccac
     4501 agtgacgaag cggctgggga aacccatccg gtggaacgcg gtaaacccct cgagcgagca
     4561 acccaaacaa tggtaggggc gctttttgtc tggaagaaga acaggacaaa aaggcagtat
     4621 aactgcagat agatggttac cgctttgttt tttctccctg gaaaagcaaa gtacagaaca
     4681 tggcttatag aaaaccgcaa acatcaggga attaggtcgt gacaaaagta atgcgttata
     4741 agaaacaaga aaaacatttg aaagctattt ttcaatactt cagatgaatc gttcttatta
     4801 caaaacaaac ttttgtatca ccggttattc ggaatttgag taaaagtgtg gggtaggact
     4861 gatgtcccac ctcctttttt tataaataag gagattgtgt atggaaaaaa acaggaagtt
     4921 caacctcgtc gcaactgcgg caagcgggct agaagcactg gttggtaaag aattaagaga
     4981 tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt tttgaaggaa caatggaaac
     5041 gatcgctaca gctaatttat ggttacgtac agcagatcga gtaaaaatcg tggttgggga
     5101 attcgatgcg tatacgtttg atgaattgtt tgaaaacgta aaagcattgc cttgggaaga
     5161 ttttcttcca ctagatgcag cttttcctgt agctggaaaa tcgatcaagt cgaaactata
     5221 tagcacacct gattgccaag cgatcacaaa aaaagcaatc gttgaacgtc tccgtaccta
     5281 ttatcaccgt ccagcttctg taccactgac ggaaactggc gcacattttc agttggaagt
     5341 agctttgctg aaagaccatg tgatggtaac tctggatacg acaggaccaa gtttattcaa
     5401 acgtggttat cgcttagaaa aaggtggagc accattgaaa gaaaacatgg cagcagcact
     5461 tattatgttg acaaattggc gaaaagaccg tccattttat gatcctgtat gtggttcagg
     5521 tacgctttgt attgaagcag ccttaatagg ccataatatc gcaccaggat tcaatcgtga
     5581 gtttgcttgc gaatcttggg attggttcag tcaagaaatc atggaaaatg ttcgatcagc
     5641 agccgaagaa aaagcagatt atgatattga attagatatt actggttcag atatcaatgg
     5701 acggatgatt gaaattgcca aagccaatgc agaagaaatc ggattaggct cttcgattac
     5761 ctttaagcaa caagcagtca aagacttcaa aacggataaa gaatacgggg tcatcgtggc
     5821 taatccgcct tacggagaac gtctaggaga agaagaaact gttcggaaat tatataaaga
     5881 aatgggcgat gtattccgtc cattaaaaac atggagtaaa tatatcttga ctagcgactt
     5941 agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa agaaaattgt acaatggtgc
     6001 attgcgtacg gatctattcc agtattgggg aactcgtccg cctagaaaaa aagagaaaga
     6061 cgaataatct tactaattga ttcattcaat tggatgtttg gaggaatagg gaatgaaaga
     6121 aaaagagttt ttacaagaag taaaagaaat caatcttcta caacaagctt taggaatcct
     6181 cgattgggat acacaaacag gtatgcctga aaaagctagt gcataccgaa gtgaagtaga
     6241 cagctatctt tacagcattt atttttcaaa aaaaatcggt ccaaaaatca aagaagccat
     6301 tcgctatttt tctgaacatc cggaagaatt gtcggaagtt ggaactgccg tttttgccaa
     6361 agtaaaagaa gagtatgatt tggaacatcg cgtaccggaa gatcttatga gaaaatatac
     6421 agctgccgtt tcttcagcac acggacaatg gcaaaaagct agagaaacac aacaattttc
     6481 tgattttcaa cacgcattga atcaaaatat tgaattaaca aaacagttga taccttactg
     6541 gagaaaagat gaaaagacga attatgatgt tttgctgaat caatacgaac ccgggatgac
     6601 tgtcgaaatc cttgataagg tatttgatca gcttaaagaa ggaattcttt cgatccgccg
     6661 tacgctccaa gaaaaaggga ctgaacctga aacagacttt ttaaatcgga gaatgacgaa
     6721 aaaacaacag aagagatttg tagtgaaagt aatcgaacaa cttggttatg attttagtcg
     6781 tggtcgttta gatgacactg tccacccatt tatgactgga attaatccga atgatgcacg
     6841 aatcacgaca cgatggaacg aaacagattt caaaatggct gtttttggag tgatccacga
     6901 ggctggtcat ggtatgtatg aacaagacat cgatgataaa tatgcgtata caccggttta
     6961 tgaaggtaca tcaatgggta tccatgaatc acaatcgttg tttaacgaga tcattattgg
     7021 aagtagtcgc agcttctgga aaaagcaata tcctttcttt caagaatgtg cagaaggaac
     7081 attcgatgat attccttttg acaaatttta tcgttcattg aaccatacaa aatcaagttt
     7141 ggttcgtatc gaggcagaca gtttgactta ccctctccat atcatcattc gttatgaaat
     7201 cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa ctacctgaaa tatggaatca
     7261 aaaatatgaa gagtatctgg gaatacgacc aacaaatgat gtggaaggca tcctacaaga
     7321 cgttcattgg tcaggtgcaa gctttggtta ttttccctct tatgcattag ggtacatgta
     7381 tgcggcacaa ttacttcatt ctttgcagca agaaatagat gtggaaaatg ttctagcgtc
     7441 agacgattat tctccaatca aaaactggat gtcagagcat atccatcaat atggtgcatc
     7501 tagaaaacca aatcaattaa tcatggatgc aacacatgaa ccgcttaatc cgcaatacct
     7561 gatcgactat atgaaagacc tgtattttaa tgtatatcag gtaaaataaa atacaattta
     7621 caaagatagc tgaaattcat ctaatctata gatgttttca gctatttact taagaaagaa
     7681 gtggaacgaa tggataaatt acaagtgatc gctgattata gtatggacca attagcgcat
     7741 gatcaaacag gacatgggag cgatcatacc aaaagagttg tcaagttagc tgaaaaaatt
     7801 ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg cagcagctta cctacatgat
     7861 acgattgatg ataaagtcgt taaaaatgag aacgaggcaa agcaacagct tcgtgtattc
     7921 cttcgctctt tgccaatagt agaggaacag atctcgatga ttttttccat tatcgaaaat
     7981 atgtcctttt ctaaaaatct ctctgaagcg gccgaactat ctctggaagg taagatcgtt
     8041 caagacgctg atcgtatcga agcattagga gcaatcggca ttttgcgtac tgcttatttc
     8101 ggcggtggac atgggcaccc gatttttgat cctgaactgt atccgcaaac attcaaggac
     8161 aaagaaaatt accgaaaagg cacgacagtg atcaatcatt tttatgaaaa actgttcttg
     8221 ctgtctgata aaatgaatac tgattacgga tatgaagaag ccaaacgaag agaaaccttc
     8281 atgcgtgaat tcttagaaga attttttctg gaatggtcta ttgacgatga aaattttact
     8341 ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt tgtgacagaa gtggtcagct
     8401 ccaagatatt tcggatcatt ttccgtaaaa gttacttctg gaacactgtt taccaagagg
     8461 tcgtgagcct gccgttcagc tccgagtcac aaggaacaat ttcaaaaaat agcttctcgt
     8521 gtttgatgaa tattgtaact tgtgattcgg aattggcagg agaacaccgt ttatt
//
LOCUS       DACCVH010000108         8494 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.109, whole genome shotgun sequence.
ACCESSION   DACCVH010000108 DACCVH010000000
VERSION     DACCVH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.109"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..173)
                     /locus_tag="IVV98_002597"
     CDS             complement(<1..173)
                     /locus_tag="IVV98_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7808186.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="IVV98_002598"
     CDS             complement(593..1714)
                     /locus_tag="IVV98_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP7808187.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="IVV98_002599"
     CDS             2042..3451
                     /locus_tag="IVV98_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAP7808188.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="IVV98_002600"
     CDS             3448..4176
                     /locus_tag="IVV98_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7808189.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="IVV98_002601"
     CDS             complement(4304..5215)
                     /locus_tag="IVV98_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7808190.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="IVV98_002602"
     CDS             complement(5232..6239)
                     /locus_tag="IVV98_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP7808191.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="IVV98_002603"
     CDS             complement(6236..8365)
                     /locus_tag="IVV98_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7808192.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="IVV98_002604"
     CDS             complement(8370..8477)
                     /locus_tag="IVV98_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808193.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DACCVH010000109         8162 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.110, whole genome shotgun sequence.
ACCESSION   DACCVH010000109 DACCVH010000000
VERSION     DACCVH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.110"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            202..903
                     /locus_tag="IVV98_002605"
     CDS             202..903
                     /locus_tag="IVV98_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7808194.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1512..2528)
                     /gene="tsaD"
                     /locus_tag="IVV98_002606"
     CDS             complement(1512..2528)
                     /gene="tsaD"
                     /locus_tag="IVV98_002606"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP7808195.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2525..2989)
                     /gene="rimI"
                     /locus_tag="IVV98_002607"
     CDS             complement(2525..2989)
                     /gene="rimI"
                     /locus_tag="IVV98_002607"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP7808196.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2996..3538)
                     /gene="rimI"
                     /locus_tag="IVV98_002608"
     CDS             complement(2996..3538)
                     /gene="rimI"
                     /locus_tag="IVV98_002608"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP7808197.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3522..4346)
                     /gene="tsaB"
                     /locus_tag="IVV98_002609"
     CDS             complement(3522..4346)
                     /gene="tsaB"
                     /locus_tag="IVV98_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP7808198.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4435..5415)
                     /locus_tag="IVV98_002610"
     CDS             complement(4435..5415)
                     /locus_tag="IVV98_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7808199.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5439..6923)
                     /gene="galT"
                     /locus_tag="IVV98_002611"
     CDS             complement(5439..6923)
                     /gene="galT"
                     /locus_tag="IVV98_002611"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP7808200.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6935..7924)
                     /gene="galE"
                     /locus_tag="IVV98_002612"
     CDS             complement(6935..7924)
                     /gene="galE"
                     /locus_tag="IVV98_002612"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP7808201.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2320 a         1729 c         1424 g         2689 t
ORIGIN      
        1 atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa ttattcaata
       61 ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa acttgtttct
      121 aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa
      181 caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc
      241 agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat
      301 actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa
      361 cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact
      421 tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga
      481 gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct
      541 gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa
      601 aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc
      661 gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca
      721 aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc
      781 ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta
      841 gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa
      901 taacgcgaac aaaaataagc agtgaccctg ataaatatca gggtcactgc ttattttcct
      961 ccctaaaact tctgaaagat ccggcagttt tagatcactg gacaagactc aaagattttc
     1021 tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgtta gattaactag
     1081 atgaagcgtc ttgtcctcat ccgatctaga ttattcgata ttcctcgaca ataaacgatt
     1141 actcagtgag ggcaatcaga ggaacggata atgataaata agctgtaaaa aatagcaaaa
     1201 taacaataat gattaaaagt atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc
     1261 tatttcgatt aaacggtgtg tacctgtcaa ctcttcggtc acaagtcata atgttcataa
     1321 acatgaggag ctgttttttg aaattgttcc ttgtgaatca gagttaaacg acaggcttac
     1381 gaactcttga ttaaacggcg ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc
     1441 aaaaacatga gaagccgttt ttcctgggct gttcttatta cttgatgcag ggcagctttt
     1501 tcacaacctc tttattcaga taaaaccaag cttggatcag cattcaactg atagctagca
     1561 aaatttcttt tttgcatttc cacatgtgct gctgctccaa tcattgcagc attatctcca
     1621 caaagtcgaa gagggggaat cactagttct acctcaggga gtttagctgc caaagcatcc
     1681 tgcaatcctt cacgcaaccc ttgattggcc gctacacctc cagctataat cagttgcttg
     1741 actggataat tttgacaagc tcgaagtgtt ttagtaatca atacatcgat cacacttgct
     1801 tgaaagctag ctgctaaatc atttttgtct agatcttctc cacgctgttg tgcattatgc
     1861 accaaattga taaatgcact ttttaatccg ctaaaactga aatcataatt atcttcatgg
     1921 atcatcgctc gcggaaaatg gtaattatct tttccctgat gagctagctg atcgatttct
     1981 tttccgcttg ggtaagaaag acctaatact cttccaactt tgtcataagc ttctcctgct
     2041 gcgtcatctc ttgtctcccc aatgatttca tatgatccat cttcttgcat atagactaat
     2101 tctgtatgtc ctccgctaac aagaagtgcc atcaatggaa actggaatgg tttaaccaga
     2161 cgggctgcat agatatgccc tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc
     2221 caagcaaaag ccttagctgc agaaatacca atcagcaacg agccgacaag tcctggtcca
     2281 taagtgacag cgactgccga taaatcttct gccgacacac cagcttctac cagtgcatct
     2341 tccaagcata aggtgatttg ttctacgtga tggcggctag ctacttcagg tactacgcca
     2401 ccaaaacgtt tatgactgtt tatttgagaa gcaacgatgt tagataagat ctctgttcca
     2461 tttctaacga ccgctacact cgtttcatca caacttgatt caatcgccag aatcaattct
     2521 tcattcattt catcgtctcc gtttttaact ttctgctcat aatgatcgca tcttccgtcg
     2581 gattgcgata atatgatttc cgtttaccta atatacgaaa cttttctgat tcataaagtt
     2641 ttcttgctgc ttcattagat agacgtactt ctaaaaaaac atgcagcgaa tcttttattt
     2701 gttccgtaat cagtaattgt aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg
     2761 caacagcaat atttgtgatc tcgacttcat ctattacttt cgagtatcca ataaagccac
     2821 agatctggtt atcttcagct aaaagcagat aatcagagtg aggctgttgg atgtctgcca
     2881 aaaactgcat tttcgtccaa ggtgaaccat gtggataagc attttcgcta atcatccata
     2941 cgcattctgc caagtacgct tcatcaaaat ctttttttct gcaaatcaac taatctcact
     3001 cattttctaa aagttttatc atatccaacg catcttcttt tgtttcagtg taatatcttt
     3061 ttttgatcgt tgttgcttga aaccccaatt tccgataaag tctttgtgca tcttgattac
     3121 tcatacgcac ttctaatgac atcgtctcac agcgattcat tatagcaaag ttctcgattt
     3181 cgtcaataag cagcgaaccg attcgtttac gctgatatgc cggtcgaacg gcaatattcg
     3241 tgatatggca atctaaaccg aacgctcttg aaccgataaa accaatcatt cttccattat
     3301 caaagatacc tagatataga tgaggaagcg gtgacttcaa ttctgatata aaggcacttt
     3361 ttgtccatgg caattcgcca ttatagactt ctcgttcgac atccagcagc tctttgatat
     3421 cttctgtagt caattctctt agtacgtaac gacgatcgat ttgttcgact gttttttctg
     3481 tataaatcat tttatcttga aaaaagcttc tggcatacgc tctaaatttt ttcaacataa
     3541 ctttcgtctc caggtgtgtg cgtctccaac catttttctt ctgcttctac tcgttttaaa
     3601 tagcgaggaa gaaaagcttg tttctctgca actggttcaa ctaaagcacc taattgagcc
     3661 acagttacac cacttggaat atcccatgct ggaactgtat taatcatcgc actaggcaat
     3721 atttccttta tttcagagaa gaatttgtga caatcactcc cgacgaaata aatagcttca
     3781 ttcagctttt gtagttgtgt gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca
     3841 gtttctaatc tattttcttt ccagcggtat gccccagcgt atacattttt tcttcgagca
     3901 tcaaacatgg gcacaataat attatccaca ccgatgcaat tagccgcgat ggttttcaga
     3961 ctagatactc ctactagctc tttatctaat gtataagcaa tcgtttttgc tgtcgttaca
     4021 cctatacgaa gccctgtata agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct
     4081 tttggactta tttgaagatc tgcaaacaat tggtcgattg caggcatcag tgttacactg
     4141 tggttgcgtt tgatatttgt ttgtatttgt ccaagaattt gttcgtcttc taccacaccg
     4201 atcgccaaag tttggtttgc agtatctatt cctaatgtaa tcatatattt gatcctttct
     4261 gctatgacat tctcgccttc cattgtagca tactttttta ttctgaggat gaaaatacca
     4321 aaggcaaaac tagtacaata atacatgatt atctgctggc gggcaaattt tgccccttcc
     4381 tgaaacacaa aaaagctgcg gtatcactcc attttcccac agcttttcca tcttttattt
     4441 cgttgattct cgaataatca actctgtttc cacaataatc tttcttgaaa ccggtgcttt
     4501 ggaattactt aattgaagaa tcgtctccac tgctagctct cccatccatt cggtataaac
     4561 ttttacagta gaaagcgagg gcgttacata tttcgctaca ctgacatcat tgaagcccat
     4621 cacagaaata tcttctggta ccactaaacc tttttcttga atcgctttca gtgcgccaat
     4681 cgctaatgca tcattagctg caaaaagcgc atcaggaaca tgcggattcg tttttaaata
     4741 ttgcttcact gcttgatatc ctgactcgac agaaaaatct gcttcgataa ttggaccttc
     4801 gtcgtagcct ttttctgcca aaacttgttg aaatgccata attctgggat cttttagccg
     4861 ctgatggttt ttcttcgtat attctgttcc agcaagcata gcgatatgtt gcgctttatg
     4921 ggagacaaag tgttcaatga ctttttgaac acttgactta aagtcgacaa ctagagagtc
     4981 gattccttga gaagtgccgt cagaatctac caaaagcaag gcattttggg atcctttcat
     5041 ttctaataac tgagcttcgt cgaattttcc tagtgcgatc gttccatctg ccggaagatc
     5101 actaatggaa tcccacgttt ctttcaataa agtaacgttt gcttcttctg cctttttttc
     5161 gattcctagg cgaatagata aataataaag atcttcaagc tcttccgtat cgtcgtacca
     5221 ctggatcagg cgaagcgttt gcttagtatt tgctgcattt ttacgatgtt tcgtataatt
     5281 taagcgttct gctgcttcaa aaattttttg ctttgtggct aagccaacgg aaagatcagg
     5341 atcatagttg agaactcttg aaacagtagc aggagaaact cctgccaact gcgcaatgtc
     5401 tttaattgtt gccatttgtc tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt
     5461 tcaaacgctg cctgtccttt ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt
     5521 gcaaaaacct gacctacaga tttttgtacg acatcggtga ccgtatcttt cgtcaaatca
     5581 ggatgttctt tttttaattg ttctgcccac ggacgatgat attcagccat ctggttttct
     5641 tctcctaata agaaatgctc tacttctact agttctggtt tcaaacgagg tggtaaaaca
     5701 gcaagcccca ttacttcgat caacccaatg ttctcctttt tgatatgttg gacatcttta
     5761 tgtggatgaa aaatcccatc aggatgttct tctgaaacat tgttgtctcg aaggacaagg
     5821 tccaactcaa agtaattgtc ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta
     5881 ccatctgctg aaaaagctct gatagatact gtttcatccg aatatgcttt ccatttttcc
     5941 aatactgagt tagctgcttc aataagcaag tttttctctg ttgattgcaa acggatcaca
     6001 gacatcggcc atttcacgac tcctgcgatg acttgcggat aatcttctag tttgataagt
     6061 ttttctatcg gtgcttttgc cataggaaat tcatgacgtc ctgcctgata atgatcatga
     6121 gaaagaatcg atcctccaac aattggtaag tcagcattcg aaccaacaaa gtaatgaggc
     6181 aagacttcag taatccgaag cagtctagca aatgtttcct ttgtgatttt catcgggcgg
     6241 tgttgttctg ataaaatgat cgaatgttca ttgtaataag cataagggga atattggaat
     6301 ccccagcttt caccgtctag attcattcga ataatccggt gattggtgcg ggctggatag
     6361 ttcaagcgac ctctatatcc ttcgttttcc atgcaaagca tgcaggtagg atagtctact
     6421 tttaccgcct cgcgttctgc tgcgatttgt tttggatctt tttctggctt agataaattg
     6481 attgtgattt ccagttcacc atactccgac tctgccggaa atttgatgtt ttttgcgatg
     6541 gctcttgttt tgatgtagtc atttttctta cttaaattaa agaaatactc agttgcttcc
     6601 tctgggcttt tcgaatagtg ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg
     6661 agaaaatcca ttaattgcgc ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca
     6721 ccattttctc ttgccttagc gacaagctga tccaataagt ctacagattc ttccttaact
     6781 ggtcttactt caatgctttc tagagcatct tctcctacca tccctaaaag acgattctgt
     6841 aaatataagc ggtccatttc catccatccg ccagcttcga tcgcaagtgt ggcaaaatca
     6901 caaatcgttt gactgattga catatctcat tcccctattc ttcataacca tttggatggc
     6961 tgacatgcca atcccatgct gttttgataa tcgctttgat atctgtgtat tcaggtttcc
     7021 agcccagaat ctctctcgct ttttcacttg aagcgactaa tcggctagga tctccagctc
     7081 ttcttggtgc tatttctgct ggaatttctt ttcctgtcac ttctctagct gcttctagca
     7141 tttccttgac tgagtatcct ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt
     7201 ctttcaagta ttccaaagct aaaatatgtg cagcaatcaa atcttctact tgaacataat
     7261 ctctgataca tgttccatct ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc
     7321 tttgaccaag agctacttgt aaaatgattg ggacaagatg cgtttctggt gtatgatctt
     7381 ctccgataga tgcatctgct tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc
     7441 gcatgccata tgcttggtca caccacttca tcattttttc catcatcaat ttactttcac
     7501 catacggatt tttaggatta gctggtgtat cttctgtgat tggagactct ttcggctctc
     7561 cataagttgc tgcagtagaa gagaatacga ttttattcac gttgaactcg tgcatgactt
     7621 caagtaagat ttgcataccg tatacgttgt tgttgaaata catcaatggt ttttcgacag
     7681 attctcctac taaagagctt gcagcaaaat ggattactcc ttcaatcggt tccttttcaa
     7741 atacggaacg tagaaattct ttatcccgga tgtctccttc ataaaaatga gcatctggat
     7801 gtactgcttg tttgtgacct gtgagcaaat tatctaccac agctacttga tacccctttt
     7861 gaactagctg gtctacagcg tgcgaaccga tataaccggc tccgcctagt actaaaattg
     7921 tcataaaaaa cactcctttg attagtaaaa ttgtgtttgt tgattctata taatttaaaa
     7981 aacgaagttt acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta
     8041 aatttataat aaaacattta gtaaacattt tcaagggttt tttgcaaagg tttacaaaca
     8101 aacgtaaaac tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg
     8161 ag
//
LOCUS       DACCVH010000110         7931 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.112, whole genome shotgun sequence.
ACCESSION   DACCVH010000110 DACCVH010000000
VERSION     DACCVH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.112"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(723..2069)
                     /gene="gor"
                     /locus_tag="IVV98_002613"
     CDS             complement(723..2069)
                     /gene="gor"
                     /locus_tag="IVV98_002613"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP7808202.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2203..3444)
                     /locus_tag="IVV98_002614"
     CDS             complement(2203..3444)
                     /locus_tag="IVV98_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP7808203.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3462..4385)
                     /locus_tag="IVV98_002615"
     CDS             complement(3462..4385)
                     /locus_tag="IVV98_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP7808204.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4606..7098)
                     /locus_tag="IVV98_002616"
     CDS             complement(4606..7098)
                     /locus_tag="IVV98_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP7808205.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(7105..7572)
                     /locus_tag="IVV98_002617"
     CDS             complement(7105..7572)
                     /locus_tag="IVV98_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP7808206.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7708..7781)
                     /locus_tag="IVV98_002618"
     tRNA            complement(7708..7781)
                     /locus_tag="IVV98_002618"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7745..7747),aa:Arg,seq:acg)
     gene            complement(7839..7912)
                     /locus_tag="IVV98_002619"
     tRNA            complement(7839..7912)
                     /locus_tag="IVV98_002619"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7876..7878),aa:Pro,seq:tgg)
BASE COUNT         2213 a         1717 c         1283 g         2718 t
ORIGIN      
        1 ggcttaatac cgagaaactg gcttttgaac accgtttatc agaggttgtg aaaaagtcgc
       61 ttagtttcga gtattaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
      121 tggcttaata ccgagaaact ggcttttgaa caccgtttat cagaggttgt aaaatcagtg
      181 ttttgtcctg agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt
      241 tgagctaata ccgaaggaca gctgattgaa cactatttgt tcggaaaaag tgactaacta
      301 tgacacaatt tttttcacag tccctttttt cacttgattt gattcgtacc agcgaacttg
      361 acgagaactt tcttggtttg gtaactatat ggtattcttt taacatcctc gtttgcttct
      421 tctaatttat ttatacaaag tcacactttt ttaaacatct gttcttcgat acatttctat
      481 ttcttttaaa catcgatacc aatattttga acttaagagt gcataccaaa tggattcatt
      541 tactcttcgt cagttacgaa gataatcaaa atctccaact tccctactta tttcgttttg
      601 agaattatcg aagcaatctt acataaataa ctaaaaaaca aaaaaccaga aaatcagtat
      661 actgattttc tggttttaca tggtttgttc aataaaaagc tgttggaact gttaatatta
      721 aattatcgca tcgttacgaa ttcttccgct cctgttggat ggatggctac tgtattgtca
      781 aagtcttctt tagttgcacc catcttgata gccacggcaa aaccttgcag catctcatcg
      841 acaccaacac caatagcatg taagccgacg attctttctt cttttccgac acagatcaat
      901 ttcatttcgc atttttggcg ataatcattt aatgcaaagt acattggggt aaagcgtgaa
      961 cgataaactt tcaattcatt ttcgccatat ttttccaatg cttcttcttc tgtcaaacca
     1021 attgttgcaa ttggtggatg cgtaaagacg actgtcggaa caagtttata gtcaagataa
     1081 gaatctttct ttccattaaa taaacgttct gataaacgtc taccagctgc gattgcaaca
     1141 ggagtcagat ctaatttacc gatcacatca ccaacagcaa aaatatgttc atccgttgta
     1201 ttttggtatt tatctacttt gataaaccct tttttgtcca attccacatt tgtattttcc
     1261 agacctaatt tttcggtatt cggtacacgt ccaccggcaa aaagtacaca atcaccagtt
     1321 aaggtttcac cattttcaaa tagcaccgta tattcgtcat tgtttttagt aatttcttta
     1381 gcaatatgat gtgcgtaagt ttttattcca gcttcttggt acatttggat caaattgtcc
     1441 gaaagcattt tatcaaacgt tctaagtggt cgttcttttc gatatgccca catgacttca
     1501 ctacctaaac cacgaaatac acctgaaagt tcagccgcaa tgtatccagc acctaaaacg
     1561 attgctctct taggtaactc tgttaattca aaaaatccat ttgaatcaat tgcgtattct
     1621 ccaccaggaa tggtcatttt acttgcacgg cctccagtag cgatcaagat tttaggagca
     1681 cgataggttt caccgtttac ttcgatcgtt tgactatcga taaaagtagc gtaacctttt
     1741 atagcctcga catgattgct atctaatcct ctttgataag caccgtgtag aaaatcaata
     1801 tatttttctc gtctttctac tagaccggcg aaatcaacat tttttaaatc tgcttggata
     1861 ccgtaacttg aggcatctcg ttcaattgtt tccaaaatcg tacttgcttg ccacataact
     1921 tttttaggta cacaaccgac gttgacacat gttccgccca attcattcgc ttcaatcagc
     1981 aaaacttttg cgccatgcat ccctgctctg tttgctgaag caataccgcc agagccgcca
     2041 ccaattacga tgtaatcata tatttgcatt ttgttcctcc ttattgaaga gatcaatcaa
     2101 aacctttatt taacgatcct ttttctacag aaaacaagtg taacactttt cttgaatttt
     2161 gtatgcgaag atgcttaaaa cagggatata tcagcttttt ccttatttac gttttcggat
     2221 catatctcca ggtttcaccg gctgtgcgac tggcatagtt aaaatcatca ttggatttgg
     2281 tgctcggtca atggattcgc cttcttcatt atgcataact tcaacggttt gactgaaatg
     2341 actgaatcct ggaccataaa attcgatttc atctcctaca gaaaacaagt ttctctgacg
     2401 tatcgtagca atctgtgttg cctcatcata agataatact tcaccgacaa atttatatac
     2461 tgggatttta cgacgttcac cgaataattg ttcgttttca gttggtgtat tgtagtaaaa
     2521 acctgtagct aattctcgtt gtgctacttt ccataactcg tcgatccatt cttgcttgca
     2581 gacatagttt tcaggatctt ccatataact gtctacagcc gctttataga catttgacac
     2641 cgtagataca taatggatcg atttcattct tccttcgatc ttgaagctgt ctacgccgtt
     2701 ttcaatcaat tctggaatat gttcgatcat tgacatatcc actgcactca tcgagaattc
     2761 ttcttccact tcgcctgtat cagttaaact gtttcgttct tgaccaaaag gcatatcgaa
     2821 caatccatac ttccagcgac aagattgaga acatccgcca cggtttgcat cccgcatcga
     2881 catatggttg gacaatgtgc atcgaccaga ataagagata cacatggcac catggataaa
     2941 tgcttcgatt tcggtatccg tatttttacg aatctctgcc acttcctcca ttgaaacttc
     3001 acgagctaaa acgacacgtt ccaacccttc ttctttccag aattccaatg tctcaaaatt
     3061 agttgctgaa gcttgagtgg ataaatggat cggcagacct ggggcttctg tcgcacaaat
     3121 ttcgatcaaa gctggatcag aaacaatcac tgcagaaata ccgacatcac gcaaactgcg
     3181 gaaaaattcc cctgctccat cttcatttcc ttcatgggtg accatattag cagcaacgta
     3241 taccttcgca tcatgttctt ttgcaaaagc aactccttca gccatttctt cataagtaaa
     3301 attacctgca cggcttctta aaccatatgc attcccgcca atatatactg catctgctcc
     3361 ataatggatc gcggttttta acttttccag tgttcctgct ggcgctagga tttctggtcg
     3421 tttcaatttt ctttttactg tcatttcttt catcatactc cttatttgat agcagaagga
     3481 tcaatataaa agaatcctgt atctaattca cggttttcag gatgcaattt actgatttcg
     3541 ctagtcattt tttccgcttt ttcttgatcc cagctacctt ctaaaatttg tttttttgct
     3601 tcggcgaata gtcgagtgat gtttacgaat ttttcgcctg gagtaaataa tccgtccaat
     3661 ttccatgtac agtaatgatg ctgataaagt tcattcaatt cattcgagag attcagatca
     3721 ttgctggcaa aaatatgtgt gccatgacta tcttcataaa tagaataatg tgtctcttct
     3781 tttttaggtt ccgagataaa aagacctctt tcacgatctt tttgttcgtc ttgtttcgta
     3841 tagttatagt aattctgtag cagtggacgt ttggattgat ggatgcatgt agcaccatac
     3901 acaagggttt ctacaggaat atcgagtttt tcttccatcg ccttcatctc ttcaaaagga
     3961 acttcacgag caagtactgc tccaactgcg ccttttttcg cccagaaatt gatttgacgt
     4021 gcgctcgtta ctaatgtttc agcatcataa atatacggta tacgcaattc aggatttttt
     4081 ttcatcgtat aaataatacc tgtatcacca actgtgatca catctacgtt tatttctttt
     4141 aaaaaagcca aatattcagg tacatttttc attttttcag gatgaatgat cccatttaca
     4201 gcaatattcg cttttttacc atacttgtgt gctaattcta ccaattgtcg ctgttcttct
     4261 cgtgtaaatg aagcaggcag acgcaatcca aattgctctt caccgaaata tagtgtatct
     4321 gcacctgcag caagcaactg ttctgcttgt tcaatagttt ctactgtggt tatgagttcg
     4381 atcataattt tctcctccta caacttcata atagtagcat agctctaaaa actttccaat
     4441 acttcttcta tttaaagtcg gatttttgaa aattatttca caaaaaatca aaataaagtt
     4501 cgatatattc tgtccaaata taaaaagaga ttgtgacaaa aatcttgtca caacctctta
     4561 atcaagtctt actattataa aaattcagct acacaggcca agtaactata gggaacctac
     4621 tgtttccttt ttaggtccgc gaacattcaa tgtgatctta ccttttgaag cacctactgt
     4681 tacgtggtca cctaaacgaa tttctccgcc aagcaaagcc tcgctcaatc gatcttcaat
     4741 ttctttttga agtgcgcgac ggattggacg tgcaccatat tcaggatcaa atccagcttt
     4801 cccgatcaca tcgattgcag atggtgtgat tttcacttga atatcttgtt ctttcaatcg
     4861 tttgataatc gctttgctca tgatttggac gattgtatgg atttcatctt tactcaatga
     4921 atggaagacg acagtctcat cgattcgatt caagaattca ggtcggaaag ctttctttaa
     4981 ctcttctaag atacgttttt gcatggcttt gtgatcttta gtaacatctt ggacattgaa
     5041 tccgacattt ttttcttctc gaatttgtgt cgctccgata tttgaagtca taatcatgat
     5101 tgtatttcta aagtccactt ttctaccttt agaatctgtt aaatgaccat catccaatac
     5161 ttgcagaagt aaattgaaaa cgtctggatg tgctttctcc acttcatcta agagaatcac
     5221 tgaatatggt ttttgacgaa ttttttctgt caactgtcca ccttcatcat accctacgta
     5281 tcctggagga gacccgatta atcggcttgt actgtatttt tccataaatt ctgacatatc
     5341 aacacggatc agggcatctt cacttccaaa catgacttct gaaagtgctt tggccaattc
     5401 tgtttttccg acaccagttg gtccaaggaa catgaatgaa ccaattggac gatcaggatc
     5461 tttcaatccg cttcgtgcac ggcggatcgc acgtgaaact gctttgacag cctcatcttg
     5521 accaacgaca cgttcatgca gaagtccttc cagttctaac aagcgttcgc tttctttttt
     5581 ctccaactgc tgtagaggga caccagtcca ctccgataca actgtagcaa catcttcttc
     5641 tgttacacga tcagaataac cttgctcctg ttttgcttca attgcagaaa ctttttgcag
     5701 ctttttacgt agtgcttttt cttgtctgcg taattgagca gcattttcaa agtcttgttt
     5761 ttggatcgct gcttcctttt cttgtactag ttcatcgatt tctagtttga tcacagttga
     5821 ttttgttaag tgatcggttt gatccaaacg gactttcgct gctgattcat cgatcaaatc
     5881 aattgcttta tcgggtagtt gacgagaagt gatataacga acagaaagat tgactgctgc
     5941 tcgtacagct tcatctgtga tctccactcc atggtgctct tcatatcttg tacgtaatcc
     6001 ttgaagaatc acttctgctt cttcaggagt tggctcatct acttgaatgc gagcaaaacg
     6061 tcgctctaat gcagaatctt tttcgatata tttttgatat tcatctaggg tcgttgctcc
     6121 gatcgtttgt aattctcctc gagctaacgc cggtttcaag atattcgaag catcaattgc
     6181 tccttctgct ccacctgcac caattaaggt atgcaattca tcaatgaata agattacttg
     6241 accatcatta tagatttcgt cgatgacctt tttcattcga tcttcaaatt caccgcgata
     6301 tttcgtacca gcaaccaaag atcccatatc aagcatcatc aggcgctttt cttgcatgtc
     6361 ttctggcact tcacctaaaa tgattttttg agctaaccct tcagcaatgg ctgttttgcc
     6421 tacaccaggt tcacccacca gtacagggtt attctttgtc cgtcggctaa gaatctggat
     6481 aagccgtttc acttctctcg aacgaccaac aactgggtcc agcttgtttt cttttgctaa
     6541 tttcgtcaaa tcacgtgcta atgaatctag cgtaggtgtt ccttgcggtg tttgccgttt
     6601 atcttgtaca tttacatttc tacgacgatt cattcctttt ccagcagaat caccagctag
     6661 ccccattttt tgtttcagaa cttgacgggc ttttgaaagg ctgataccta agttgatcat
     6721 gattcgagta gccatgatac tttcatcttt taataagctc atcaaaatat gttctgttcc
     6781 aactttttga gaaccagttt tcttcacttc gctgctagct aaagcaaaaa cttgtttcat
     6841 tcttggtgaa tatggaagaa agactccttt agggtaagaa cggataccac cataaccaat
     6901 cagatgttca atttcttcat aaatttccgt ttcattcaaa tccatttcac gtaatacttt
     6961 tccagcaatt ccattttgct cgaccactaa ggctagtaaa acatgttctg aactaactga
     7021 ttgatgtttc aaccgttttg cttcttcttg tgcaatttct aatactgctt gggctctttc
     7081 agtaaaaagt tcttccatct aatctcactt cccatcttca taacttaaac gttccagaaa
     7141 tgctcggaga atccgagcac gtgtatgatc ttcatattca ttgaaattca atgtgttttt
     7201 tgcaattgca ctcaacatca agtttccttc tttttttgta attatttggt cttcataaag
     7261 tttttgaata atagcaaaag catttttctc actgattgta tcatcaaata actgatttat
     7321 ctgctcaagt aattgttttt tatctgaaat ccttactttt gcaattcgta tataaccacc
     7381 accaccacgt ttgctttcta ctagataacc acgttggatg gtaaaacggg tattaatcac
     7441 atagttgatt tgtgaaggaa cacagttaaa gaggtctgcc atttcaatcc ttcgaatctc
     7501 gatcatttca ctattttcca gaattttctt tatatatgat tcaattaaat ccgaggtatt
     7561 ctgatgtgcc atcttattca ttccctttga ctaatattga ccttaattat aacgaatttg
     7621 ataatagaaa gaaagaagaa cgctttttgt taaataaatc ctttagaatc aacaaaaaaa
     7681 aatacggaat atactattcc gtatcgacgc gcccaagagg agtcgaaccc ctaacctttt
     7741 gatccgtagt caaacactct atccagttga gctatgggcg catattcaat ttaaaaaaat
     7801 tataaatcat ttgaaaacaa aaagcaagat aaaaaaaatc gggaagacag gattcgaacc
     7861 tgcgacccct tggtcccaaa ccaagtgctc taccaagctg agctacttcc cgtttaaaaa
     7921 ataaaaaaga c
//
LOCUS       DACCVH010000111         7733 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.113, whole genome shotgun sequence.
ACCESSION   DACCVH010000111 DACCVH010000000
VERSION     DACCVH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.113"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..177
                     /locus_tag="IVV98_002620"
     CDS             <1..177
                     /locus_tag="IVV98_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808207.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="IVV98_002621"
     CDS             190..690
                     /locus_tag="IVV98_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP7808208.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="IVV98_002622"
     CDS             787..2634
                     /locus_tag="IVV98_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAP7808209.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="IVV98_002623"
     CDS             2637..3533
                     /locus_tag="IVV98_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7808210.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="IVV98_002624"
     CDS             3583..3972
                     /locus_tag="IVV98_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7808211.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..6304
                     /locus_tag="IVV98_002625"
     CDS             3959..6304
                     /locus_tag="IVV98_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7808212.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLENGITSI"
     gene            6397..7584
                     /locus_tag="IVV98_002626"
     CDS             6397..7584
                     /locus_tag="IVV98_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP7808213.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT         2576 a         1185 c         1662 g         2310 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacggga ttacgtccat
     6301 ataattgtgt aaaagtgaag catcaaaaaa gccattgatc tcagttagga gtacaatgtt
     6361 ttttgcagaa aacatactcg aataggactg atatcaatga ctcaagtaca ttttactttt
     6421 gaaagcgaag aaattcaagc aattataaac gaaagcggtg cgaatgatac cgcaaaaaca
     6481 cttatgacta tcatgtttaa tcagctgatg gaagaacaac gaaatcaata tattcaggca
     6541 aatgcctatg aacgttcaga agaacggcaa tcacaaagaa atggttacta cgatcgttcg
     6601 tttacaactc gaattggtac gttagaactt catgttccac gaaccagaga cggtaagttt
     6661 agtcctacta tctttgaaag atatcagcga agcgaaaaag ctttgatcgc tgccatgatt
     6721 gaaatggtca tttctggtgt ctccactcgc aaagtaacta aaacagttga actgctaacg
     6781 gatggtgcga ctgtttctaa atcattcgtt tcaaatctga tgaaacagtt ggatccattt
     6841 gtttttgagt ggagaaaccg gagcctagaa ggctcggaat atccattttt catgtgtgat
     6901 gccctgtata tgaaagtaag ggaaaatcat cgtattgtct caaaaggtgt atatattggt
     6961 atcggcattg attctgatgg acgacgtacg attcttggtt ttgatgttca agacggcgaa
     7021 tcggaagata attgggatac cgtttttcaa tcgttcgttc aacgaggttt gttcggtgta
     7081 aaactggtca tttctgatgc acacaaaggg ttagttaagg ctgttcgcaa gaacttttta
     7141 ggtgcgagct ggcaaagatg ccaagcccac tttttgagaa atatttttga taagctgcca
     7201 aagaaagttt cttctgatgt aaaagacgag ttgaagagta tctttaaagc ctctgaactt
     7261 gaattgacac gtgaaagaaa agagcacttc ttggaaaaat atggttgtga ttcaaaatta
     7321 agtgctgctt gcgacatttt agaaaacggc tttgaagatg ctattcaaat tttgtctttt
     7381 cctgaaaata tccgccgaag gattcgtaca accaatgtgt tggaacggtt gaacgaagag
     7441 attcgccgga gagaacgagt gattcggatt tttccaaata tcaattccat cactcggata
     7501 attggaacac ttttgatgga aaaagacact gagtggctgg cttctccacg aaaatattta
     7561 gaatttaatt cgaataacat ttagcaccat gaacctgtgc gagtctcttc tttctgagga
     7621 gagacatcaa gagtcgctgc gctactgctc ctgacctctc tcctcagaaa gaaaggcatg
     7681 gcagttaggt tcacaacgca aaacattgtg cttttgatga ggttgaactt tta
//
LOCUS       DACCVH010000112         7396 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.116, whole genome shotgun sequence.
ACCESSION   DACCVH010000112 DACCVH010000000
VERSION     DACCVH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.116"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="IVV98_002627"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="IVV98_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP7808214.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="IVV98_002628"
     CDS             complement(1804..2697)
                     /locus_tag="IVV98_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808215.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="IVV98_002629"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="IVV98_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP7808216.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="IVV98_002630"
     CDS             complement(join(3472..4509,4511..4573))
                     /gene="prfB"
                     /locus_tag="IVV98_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP7808217.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="IVV98_002631"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="IVV98_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP7808218.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1981 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaa
//
LOCUS       DACCVH010000113         6786 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.118, whole genome shotgun sequence.
ACCESSION   DACCVH010000113 DACCVH010000000
VERSION     DACCVH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.118"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            20..910
                     /locus_tag="IVV98_002632"
     CDS             20..910
                     /locus_tag="IVV98_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP7808219.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(983..1807)
                     /gene="nadE"
                     /locus_tag="IVV98_002633"
     CDS             complement(983..1807)
                     /gene="nadE"
                     /locus_tag="IVV98_002633"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP7808220.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1819..3291)
                     /locus_tag="IVV98_002634"
     CDS             complement(1819..3291)
                     /locus_tag="IVV98_002634"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP7808221.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3928..4290)
                     /locus_tag="IVV98_002635"
     CDS             complement(3928..4290)
                     /locus_tag="IVV98_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP7808222.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4513..5265
                     /locus_tag="IVV98_002636"
     CDS             4513..5265
                     /locus_tag="IVV98_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7808223.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5405..6328)
                     /locus_tag="IVV98_002637"
     CDS             complement(5405..6328)
                     /locus_tag="IVV98_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7808224.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6343..6615)
                     /locus_tag="IVV98_002638"
     CDS             complement(6343..6615)
                     /locus_tag="IVV98_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808225.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2071 a         1351 c         1160 g         2204 t
ORIGIN      
        1 cttttaagag gtgatatata tgcaactaca aataaacgaa gaatccttac cggtatatga
       61 agcattagct agtaaaacaa ggatcaagat catccagcta ctttccaaaa aaaagatgaa
      121 tgtcaaagat ttggcaaaag aacttggagt gagcagtgct atcacgacga tgcacgtgaa
      181 aaagctagag gaagcaaaca tcatcaaaac agaaaaagta ggacaacaaa aaatttcgag
      241 ccttcgtgtc gataaaatcg atatcagttt tccagaaaaa atattcaatg cttttgatac
      301 gaaagaaaca tcgataccta ttggtcacta tacaaattat gcaattgaac caacatgcgg
      361 tttagctacg atccatgatt ttatcgggaa agtggatgaa ccacgctatt ttatggatcc
      421 tcgaaggatg gatgcccgca ttctctggtt taccagcgga tttgtcgagt atcaggcacc
      481 taatttttta aatacagagg atacattgga gatgttggaa gtttctgtgg aaatttcttc
      541 tgaatttcct ttttcaaatg acaattggcc ttcagatatc actttcagcc taaatggtgt
      601 ggagctagga acatggacga gccctggaga ttttgctgat atccgcggta aatatacgcc
      661 tgattggtat ccagataatc ttaatcaata cggcttgctg aagacgatcc gaattaccaa
      721 acacttgacg aatatgaatg gagaaccctt gtcaaacatc acgatcaacg acatccctaa
      781 agagcaagac acttggcatt tgcgaatcga agtgaaagac gatgccaaac atgtgggggg
      841 ctgtacttta tttggtaaag gattcggtaa ttacgatcag gatatcaaat taaaagttta
      901 ctacagctga tatttttctt ttctatttta taaaacaaaa acagccaatc cctatgaagg
      961 gacggctgtt tttgctttat tgttatttcc agaaatcatc caaaacggaa attggcaaat
     1021 gtcgtttatg ttgtgtcttg ttccaccatg cttcgatttt ttcttgtgct tgagcgggaa
     1081 cttcttttcc ttctagataa tcatcaattt cattatatgt gacacctagt gcgacttcat
     1141 ctgcaatcat tggtttccca tcttcaagat ctgcagtcgg aatttttgtg tataattttt
     1201 ccggtgcatt caatgcttga agcaattgtt tcccttgtcg tttgtccaaa cggaataatg
     1261 gcaaaatgtc ggctccacca tcaccaaatt tcgtgaagaa tccagtaatg ttttctgcag
     1321 catgatctgt ccctaatacg gctcctgctc tttctccagc tacggcatat tgcgtaatca
     1381 tacgttgacg tgctttgata tttcctttgt taaaatcgct gattcccaca cctgcttcgc
     1441 ttaatacttg tacttgtgca tcaacagctg gtttgatatt tactcgcaga ctaacatcgg
     1501 gctggataaa gtcaagagca gcttttgcat cttcttcatc tgcttgttca ccataaggaa
     1561 gacgaacagc gataaattga tagttttcat cttttgtttc ttcacgcatt tcttccatcg
     1621 ttagttgcgc caaacggcct gctaaagtag aatcttggcc gccgctgata cctagtacaa
     1681 aagttttaag aaacggatat tttttcaaat atgctttcat aaagtcaata cttttacgta
     1741 tttcttcttt tggatcaatt gttggtttga cacctaattc attgataatt tctgtctgca
     1801 ggctcattta ttctcctcct atgcttctgt atgaagttct gctacgcttt ttttcattcg
     1861 ttccatgata gccattttat ggttccagca ttcagtagac agatcgactg ggtatttttg
     1921 cggattcaag tctcgtttat actcttccca tagtgaatct agattttctt ttgtatattc
     1981 tttgatttcg tttagtgcag gtaattcgta aactcttttt ccttcgataa agatatcttg
     2041 taaaactggg cgagctgtaa agtctcgaac agttttattg ataaacgtat gcactggatg
     2101 gaacatgaag atagcttctt cttctcgagg gtcttcatcc cataatgtca cgtagtctcc
     2161 ttcagatttc ccatcaaaat ttcgagtgat gcgccacact tgttttttcc ctggagtagt
     2221 tactttttct gcattgcttg ataacttgat cgtatccatc atttttcctt catcatcttc
     2281 gatcgatact agcttgaata ctgcaccaag ggctggctga tcataggctg tgatcaattt
     2341 tgtcccaaca ccccatacat caattttagc tttttgcatc tttaaattca aaatcgttgc
     2401 ttcatccaag tcattcgaag catagatttt tgcttccgta aatccggctg catctaattg
     2461 ttcccgaaca cgcttagata tataggccat atctccactg tcgatgcgta cgccttggaa
     2521 gttgattttg tcacctaatt ctttcgccac gcgaatcgca cttggcacac ctgatttcaa
     2581 cgtatcataa gtgtcgacta agaacacgca gtctttatgg gttttagcgt aggccataaa
     2641 tgcttcataa tcatttccat aagattggac taacgaatga gcatgggtcc cgctagctgg
     2701 tatcccaaat atcttcccag cacgtacatt gcttgttgca tctgctccgc cgatatatgc
     2761 cgctctagtt ccccagactg ctgcatccag ttcttgtgcc cgtctagttc caaattccaa
     2821 tagtggatct tctccgatga cagatttgat acgagctgct tttgtcgcga tcaacgtttg
     2881 gaaattgacc atattcaaca gtgctgtttc tactaattgg cagtgcgcta aaggcccttc
     2941 cacttggatt aatggttcat ttgcaaaaac tagttctcct tcacgagcag aacgaactgt
     3001 tgctttaaat tcaaaatttt gtaaatactc caaaaaacct tcaggataga cttctaatcc
     3061 acgcaagtaa gcaatatcgg aatcattgaa cgtcagattc tctaaataat tgactaaccg
     3121 ttccaatcct gcaaaaaccg cgtatccgtg gttaaaaggc atttctcgaa agtaacattc
     3181 aaaaacagca tgtaaatcag ctcgacctaa ttcccagtat gtctgcatca tattgatttg
     3241 atatagatcc gtatgcagcg tcaaactgtc gtctgggtaa gtattattca tcttgtatta
     3301 ctcctcttgg caagttttca tttcctaccc attataacaa aaaaaattaa taggaaaaga
     3361 aatcttccat tttttctgaa aaagcacatg ttttacggat atttcttgct aaaaatgaac
     3421 tccatctgct aaaactatcc tttcttattg gtatttaacc taaacgagaa agaatactta
     3481 ttttattcaa tgtatccgag acacgaagaa attagcgttt tctatttttc ttacttgata
     3541 aaataagtag attttcctac tacaatcgta gccgttaaga taccgatgat tgaacaaata
     3601 taaccaaatg tctctacaac ataatcaatg gcaaaagttt ttgaagcaat aatacgtctt
     3661 tccttttttg cttcttatcc ccaaagaaac ggatataact tattatgtat tgaatttttt
     3721 tggaaaggcg aattatgaca agatatacct tgcgttgaaa aaactcgcgg aaaaaatatc
     3781 acacgttttt aaaaagatac aaagtaagaa agcagctgtc aatagaatgg aaacaaaaat
     3841 ggcgagacat caatcagtct cgccttgttt tttattgtat acattagata tggagcaggt
     3901 taccataaag atgattatta gtcgttatta aatagaatcc ttcgtatttt tttgttctat
     3961 cactacaata tctttatttg gacgtttgaa ttgtattccg gcacgttcta gctcctgttt
     4021 cactcctaca tggactttga catcttctcg tgtcattttt aaaacgtgat gaatcgcata
     4081 gtcgatttct tgccttgtga tttttttctt cgtattgatc atcacgactt gctttttatc
     4141 atatgtgtct accaatagca gttgtgttcg atctaacgaa aataatttgt aataattaat
     4201 agccgtattc ccaaaaaaga attccactac tttaggataa aatgtcttaa tatttaaatt
     4261 actattcaca ggtgtttcga ttagcttcat ctcattcctc ttttctatat agtcgattta
     4321 gatccaatct taagttatgt taccatcttt cctagcatta aggaatcggt tacaattgaa
     4381 cctttaaaga caaaaggatt taccttttat cacttaatag tataacataa tttcgtgaga
     4441 aaaaaataca attttttctt gaccatctcg ttacgtaaag gattatgctt acatttgtca
     4501 ggaggaaaaa taatggagta cacaataaag aaaatgtcag agatatcagg agtcagtccg
     4561 agaaccttgc gcttttatga tgagattgga ctgctaaaac cagctaggat caattcttca
     4621 ggttatcgga tttatggcaa aaaagaagtc gatcgtctgc aacacatctt attttatcga
     4681 acaatggcat tcaagttgga tgatatccaa gaggtcttag acaatccatc ttttgaccac
     4741 cagaaagctt taatcaagca tcagcaaatg ttgctggaaa aacgggcaca aatcgatacc
     4801 ctcttgacaa ctgtccaaca gacacttgat atgtacgaag gaggaagaaa aatgagtgac
     4861 aaagaaaaat ttgaagggtt taaacaacaa aagttgaaag aaaatgaaga atcctatgga
     4921 caagagattc gacaaaaata cggaaaaaaa aaggttacag catccaatga aaaatggatg
     4981 aatatggata aagaaacgta tgaagaaatg caaactgttg aaaagcagat gttatttgat
     5041 ctcactcttt acttaaaaga accagaagat gaaagcttag cagaccgtat cttccaagct
     5101 cataagaagt ggttctctta cagctggcct gaatatcagc caaaagcgca taaaggacta
     5161 ggaatgatgt acgaagccga tgaacggttc actgcatatt atgacgagcg aagtggtcat
     5221 ggtgcagcaa aagctttaaa tgaaattatc caaaaaaagg cgtaatcttt tacatgatcc
     5281 aacaaaaaag tacacgtaaa atgacctaat aacaaaacag cagacaccca agttagattt
     5341 ttatgctaac ttttggtgtc tgctccattc tttcacaagt tttttcatcc tactttaaat
     5401 atattcatcg ttgaataaac gtataaggta ttttcacttt atcctttttt tctgtaagaa
     5461 acaattgaaa tgccatttct ccgcaagctt ccagatggtg gtcgatggtt gggaaaccaa
     5521 gaagctcgct gatcagcaaa ttatcgcgtc caatcaccac tggtgtctta tcttgcagat
     5581 agctttgcaa gatgcctgct gcaaccatat ccgaatttgt aaagacacca tcaactccaa
     5641 gctctttaaa aaagaagcct gcttgttttc ctttctctgc atctatacaa tcccaaaaaa
     5701 caagtgattc atcaaaagat ggaaaaagtt gatgacatag ctgcaaagtg atttttgagt
     5761 tataacttag cctgccactt cgccccaacg tgatgcccaa ttgctttata ccttgctgct
     5821 tcaaataagt aagaccttct gtaattgatt gttctcgatc aataaagaca cagcttgcct
     5881 gttttccctt gatttcttca caaaaaacta gaggtccata tttttgatat gccaataaat
     5941 catctagtgt attggcacga gacgtaatga tcaatccatc gaaagcttta gctgcaaatt
     6001 cttcaagata ccttcgctct ttttctttat gatagcccgt cggtaaaagt gtcactttgt
     6061 aatcataatc aaacgctgct tcaatgatcc cactgatcaa ctgatcaaaa tacggatgat
     6121 tggtataagg cagaatcact ccaatgcttt tcgtttttcc ataacttaac tgtctggcat
     6181 ttgcattagg gatataatcg acttctttca tgaccgcaag tatttctttc cttttttcct
     6241 catctacata tggatgtcca ttgattacac gtgaaatagt agaaactgaa taacctgtga
     6301 gctttgcgat atctcgaatg tttgccactg ctgcttcgcc acctatacaa aaagattttc
     6361 ttgtaaatag tctaccacag ctggaccgca ttcaaaaaac tgatacattt ttccttcatg
     6421 cgaaaaactg atccgctgcc cgccccaata tatatctttt gtcaaatttt cgatttcatt
     6481 cattggtatt tcttttacta tattcctatt caacccttga aaactgtaca acgttaatac
     6541 ggatcccttg aactcgacaa acgcataaaa ataattgttc gttgtgccat ctgttatctc
     6601 tacataagta ttcattgcaa gccctccttt tgatactttg agtatagtgt atgaaacgcg
     6661 tctcatagca aggagtttgt tttgccaaag aaaagtttta ttcctctttc attattacca
     6721 aagtctctta ttttaaattg aatacattat aatgatactg taaatatatc tttattatta
     6781 gtgaat
//
LOCUS       DACCVH010000114         6746 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.119, whole genome shotgun sequence.
ACCESSION   DACCVH010000114 DACCVH010000000
VERSION     DACCVH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.119"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(35..868)
                     /locus_tag="IVV98_002639"
     CDS             complement(35..868)
                     /locus_tag="IVV98_002639"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP7808226.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(1060..1764)
                     /locus_tag="IVV98_002640"
     CDS             complement(1060..1764)
                     /locus_tag="IVV98_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7808227.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(1787..2413)
                     /locus_tag="IVV98_002641"
     CDS             complement(1787..2413)
                     /locus_tag="IVV98_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7808228.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            2739..5114
                     /locus_tag="IVV98_002642"
     CDS             2739..5114
                     /locus_tag="IVV98_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP7808229.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(5138..5629)
                     /locus_tag="IVV98_002643"
     CDS             complement(5138..5629)
                     /locus_tag="IVV98_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP7808230.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            5816..6736
                     /locus_tag="IVV98_002644"
     CDS             5816..6736
                     /locus_tag="IVV98_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7808231.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
BASE COUNT         2167 a         1237 c         1311 g         2031 t
ORIGIN      
        1 catttctcaa ataagagaag tgttctggtt ttttctacat tgcaataaac caataaccaa
       61 tcaaaatgat accaaggata atacgatacc agccaaaagc ggtaaagtcg tttttcttca
      121 aatagcttag taagaatttg atagctaaga cggaaaccac aaaagatacg aatgttccta
      181 caagaagaac aacagtttct tccattttga atgaattccc ttcagctaaa tatttgacga
      241 tcttcaagcc gcttgcgcca aacatgacag gaatccctaa gaaaaatgaa aactctgtag
      301 cgacaaaacg cgaagcacca atcaagatag atcctaggat cgttgcgcca gaacgggatg
      361 ttccgggaac aagtgccaag acttggaata acccaacaag aagagctgct tggtacgtaa
      421 agtcattcag agaagtccaa cgaggtgttt tgtttttgtt gcgtttttcg acaataataa
      481 aggcaatacc gtaaacgatc aaaacaatgg caactggtaa gaacttgtgg aaatttgctt
      541 ctaaccaatc atccaaaggc aaaccaatga tgatggctgg tatgcaagca acgatcactt
      601 taaaccaaag tgtccacgta tctttttttt ctaccgttga tttacttgga gaaaatgggt
      661 ttaacttgtg aaaataaaga acgacgacag ccaagatcgc ccctaattgg ataacgacat
      721 tgaacatcga cataaattgt gaactggcat ccagtttgat gaattcatct gctaggatca
      781 aatgaccagt actactgatg ggcagccatt ccgttattcc ttcaataata ccgagaatca
      841 ctgctttgat aatatttgca aaaaacataa attccttcct tcccaattaa gatacatctt
      901 atagtatacc gttatttttt gagaaaccca atctgttttt taatattaag aaaaacttga
      961 gaaataaagc agataagtac acgaagagaa aaaagaagac aaagccctcg ttcagacttt
     1021 gccttttatg attctctggt aaaaattaaa atatccccat tatagaaacg agtcgcgact
     1081 atgtgttttc ccgttatcga tataagacgt atcattgatg ccgtggatag aaaatcgacc
     1141 gtttgcataa gtgacctttg ttacgctgcc atttaaaagc ccagcacgaa caggctgttt
     1201 aggatcgatc agattaagca aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt
     1261 tccaccacca tttttttcgc agtgatgggc gatatcttca aatcctgtcc atacacggtc
     1321 tcgcaatgtt tcataagttt ccgcccaccc agcggtatct aagttgtata cagcattagc
     1381 aatttgttca aaagaaactt ctgtggtaaa catttcatca tatgttttaa aattcaatac
     1441 acgagggatc acaccccaca tttccatgtc atatccacct tcaagagacc cgaaacacca
     1501 ttctctaatc cttttttcaa taaaataagg aatttctttt cccttagaat gttctcctag
     1561 aataatacgg gcagtttcga ttgcacgacc actgtcacta gaataagcaa atgaaaagtc
     1621 gacatttttt aacccgcgac ctaaataatg aatgccttct tgtccttgct ttgtgagggg
     1681 tgtatcacac cagccttgta ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac
     1741 gatataaagt gtagtttctg tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa
     1801 aaggatttgt ccttttttcc tgttcaatcg tcgttgcatc gccatgtcct ggatagactg
     1861 caaattcatc aggtaataca aacagctggg tccgaatact atgaagtaat tgttctaaat
     1921 tccctgtata cagatcggtt ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga
     1981 caaaatcatc aaaaataaag ctgacgcttc ctatagaatg ccctggggta gggacgacgc
     2041 gaaaagacat gtttcctaaa gtataagttt tcatttcaaa ttcatattct gcaggcgaga
     2101 caataacatc agcaatatca tcatgtctac cgagtccaga aagattcaaa atcggatcac
     2161 ctagccattt ttgctctagt gggctgacat aaactgggat ttgataatac gcgcgtaaag
     2221 gttccactgc accgatatga tcgtagtgag tatgggtaag caaaatcgct accggctgtt
     2281 ggtttgtttt tttgatttct tgtttgattc gttccgcatc ttctccaggg tcaatgatca
     2341 aaagtgcttc ttcgttgtag accaaataac agttttcttc aatcattcct gtttttaatc
     2401 tttcgatatg catgtgcatt cctccttgat agccaaaact tctttcatcc attagtataa
     2461 cgcattcatt gctaggaaac aaaaacaggt acttatttct ctttacttat ctgaattatc
     2521 agactatatg aaaagtattt ggatattcta aagagaagga aagtaagttt tcatagcatt
     2581 ttaatatgtc cttgttacat tagattcatc caaaaatcca aattctatat cctatatccc
     2641 tgcctaatca gcagggtgtt tttttatgtt tggaaagaga gctctttttg ctaaactagg
     2701 ttttttcagg taatcttaga gagaaagagg tggtggaaat gatcaaacag tcaaaaatat
     2761 ctgtgcggca cttagtagaa tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa
     2821 gtaaccatac tgcattagaa ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag
     2881 aaaactatga aaaagaagtc tttttaaaaa caacagttca attagatgaa tattacctga
     2941 tcgttgaagg ccgtgcagac ggtattttca aaagagacgg tatttattat atagatgaaa
     3001 tcaaaacctc cgaaccacga tttgaagatt tagaaccaga acaagtggaa cttttctttc
     3061 atcaagcaag ggtgtatgcc tatatctata gtcaagaaca tgatttacaa gaaataaatc
     3121 tgcaattgac ttacttccag acggcagaag aagtgatcac gagaaaggtt gaacatcaga
     3181 caagagagca gttagaaact ttttttaaaa agctgactga agattataaa gaatggcttg
     3241 tttttcaaga aaactggcgc actgtacgca atgcctcttt gatggctttg aaattccccc
     3301 atgatgagta taggaaaggt cagcgtgaac tagcggtagc tgcttataaa acgatccgta
     3361 cgaaacagaa attgtttgta gaagcaccta ccggaacagg aaaaacaatc tctacgttat
     3421 tccccgcttt gaaagctgta ggggaagaag agggagaaaa gatcttttat ctaacggcta
     3481 aaacaataac tagacaagta gctgaagatg ctatgacagc attaaaagat acaggagctg
     3541 aagtaaaaag tgtcactttg acggcgaaag acaagatctg ctttttagat gagacgacct
     3601 gtaatccaga tcagtgccca tatgccaatg gttattacaa tcggattaat gaaggtttat
     3661 gggatctttt gaatcatgag aatcagatca ctcgtgaagt catcgaaact tatgcaagaa
     3721 agcatacact ttgtcctttc gaactatcat tagatgtcag tatctggtgt gacgtaatca
     3781 ttggggatta caattattta tttgatccaa ctgtttattt aagacgtttt tttgaagatg
     3841 aaaaaaacga ggactatctg tttttgattg acgaagcaca taatttggtg aatcgttccc
     3901 gagagatgta ttcggcagaa ctatcttatg aaaaaacgaa acgaagtaag gaagctatac
     3961 caaaggaatt caaaaaactt catcgccgtt tcaacaaact attaaaagaa tttgattcga
     4021 tccgagaaat agcaaaagaa gatcattggg attatcatca tcaaaaagca ccggctgaat
     4081 ctttagtaaa ggcaggttat caattaagcg aaaaaattaa agaatggctg gcagaatttc
     4141 ctgagcaccc atcacaagaa caattgcttc cttattattt tgatttgctt cattttttga
     4201 aggtcagtga attttatgat gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc
     4261 tgatagtaaa agagttttgt attgatccaa gcttgtttct tgagcagtcg ttggataaag
     4321 gaaaaagcag tattcttttt tctgctagtt tttcaccact ctcttattat caggaaacac
     4381 tggggggaca aaaaagtctg gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc
     4441 aagttttcat cgcaaattac ctagagacga cttatcgaaa aagggaacac agtctggcaa
     4501 aattagtaga gacgattcat gcttttgctg atggaaaggt cgggaattat ttcgttttct
     4561 ttccttctta tcaatattta gatcttgcgg tggaagcatt cagacagcaa tatcccgaca
     4621 gcaatgtgct aatccaagaa acggacatga atgaggaaga acgcgaacga tttttaacaa
     4681 aatttcaaac aaatcccgct gaaacattga ttggattttg cgtacttggc gggatttttt
     4741 cagaaggaat cgatttgaga ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt
     4801 tgccgcagat gaatcatgag caggaactga tcaaatcata ttatgatgag aaggaacacc
     4861 ttggatttgc ttacgcttat cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc
     4921 gagtgattcg tggcatggcg gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta
     4981 gtttttctta tcgacgttta ttcccacaac attggcaaac agcaagagaa gtacgaagtg
     5041 ttggggaatt ggaagaagga atacagcgtt tttggttatc aaaagaagca gtaaatcaaa
     5101 aaaacgagga atgacagacg tcagcctcgt tttttgatta acgatagtta gtgaattgca
     5161 actcgattgg taagtcaagt ttacgtaata aagcaatcac agcttgtaga tcatcacggt
     5221 tcttacctgt cactctaatc tgatcttctt ggatttgtgc ttttactttc agtttttcat
     5281 ttttgatagc tgtagtgatt ttcttcgcgt tttcacgatc gattccgttg accaaatcgg
     5341 cagtttgtcg agctttgcca cctagagcgt gttctgattc ggaaaaatgg atatttttga
     5401 ttggcacatt tcttttgatc agcttaccaa ataatacatc tttgatctgt tcgattttga
     5461 aatcatcatc gctcaataca actagattgc tgttctctaa tttgatttct actgtagaat
     5521 ccttgaagtc aaagcgattg gacaattctt ttgttgtttg ctgaatcgca ttttttactt
     5581 cttctgtatt gacttctgat acaatgtcga agctagcatc ttttgccata ggaaccctcc
     5641 tgatatacat ataaatattt accatacatc tatcttatca taggattagg gcagattctt
     5701 acctgtttgc taaaattctt ctcatttgag ttcgaagtat tttattttaa tagataaact
     5761 gttattctta catttggaat accaaagtag gggagaggtg cttgtgagta aaattatgac
     5821 tgcgtatcat aaaaatgaaa gattaaagaa aatagtggtt attttgataa ccggattgac
     5881 cgctgcggtc gctttaaatt attttttgat tccagccaat gtcttttctg cagggatgaa
     5941 tgggatcgct caaatcattt cctcgctttt atatgaatgg tttcatatca agatagacac
     6001 aggaacattt atttttcttt tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg
     6061 aaaacgagca acgatcctta gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct
     6121 gcttccagtc ggacagatca ctgataatat tttgatgaat gccctagtag gcggtgtttt
     6181 attaggtctt ggcgtaggat tatctttaaa aatgggcttt acaactggtg ggatggatat
     6241 catctctctt gtactttcac aaacaactgg aaaaacagtc ggaaactaca tgctgattct
     6301 aaatggtatc attgtagtca tcgcaggctt cttctttaac tgggaaagtg ccttgtatac
     6361 gattatttcc atttatgcaa tgactcaagt aattgatgcc atccacacga gtcatcaaaa
     6421 agtaacagca atgatcgtta ccgtcaagcc agaagaggta acagaagaac tagcaaaacg
     6481 gatggtacgt ggaatgacat tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa
     6541 catgatcatg atggtcatca cccgctacga aatgtatgat cttgatcaga tcgttcatga
     6601 aatcgacgac gatgcattta tcaatatttt accaactcat tcagtatttg gccggtttgc
     6661 aaatgaaaac gaacaaaaaa tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg
     6721 ttcacaaaaa aaatgaggaa tcaggt
//
LOCUS       DACCVH010000115         6568 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.120, whole genome shotgun sequence.
ACCESSION   DACCVH010000115 DACCVH010000000
VERSION     DACCVH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.120"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            5..400
                     /locus_tag="IVV98_002645"
     CDS             5..400
                     /locus_tag="IVV98_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7808232.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            397..1398
                     /locus_tag="IVV98_002646"
     CDS             397..1398
                     /locus_tag="IVV98_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7808233.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKGISAKFALKNKWVFLIYIYNKLIKR"
     gene            1404..2450
                     /locus_tag="IVV98_002647"
     CDS             1404..2450
                     /locus_tag="IVV98_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7808234.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            2464..3543
                     /locus_tag="IVV98_002648"
     CDS             2464..3543
                     /locus_tag="IVV98_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7808235.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            3586..4986
                     /locus_tag="IVV98_002649"
     CDS             3586..4986
                     /locus_tag="IVV98_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HAP7808236.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            5032..6537
                     /locus_tag="IVV98_002650"
     CDS             5032..6537
                     /locus_tag="IVV98_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase"
                     /protein_id="HAP7808237.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
BASE COUNT         2404 a          761 c         1195 g         2208 t
ORIGIN      
        1 agatatgttt tgcaaagtat gtgatagaaa agagggattc tgtggcttca gaatagatat
       61 caaagaattg gcaaaagttt ctgatatttt tttatttact acattacaag aaggaatgcc
      121 aagatctatg atggaagcta tggcaagtgg attgccatgt atagcaagta aaatccgagg
      181 taatgtagac cttttagtgg aaggaaaagg tggatatctt gttccagcta aagatgcaga
      241 attagtagca gagtgtttga gagaactaat caataataaa tctcttagaa agtatatggg
      301 aaatgagaac ctttccagaa ttaaagaatt cgaggttagt atcgtaaaaa aaagaatcaa
      361 agaaatatat gaagaagtta taggtgagag tgtaaaatga aaaatccaat gttttcaata
      421 atagtaccta tctattgcgt tgaaaaatat ttgaaagatt gcttagattc aataagaaat
      481 cagacattta aaaattttga agcaatacta gttgatgacg gtagtcctga cgaatgccca
      541 gaaatatgtg actattattc ccaaatagat ggacgtttaa aagtaattca taagaaaaac
      601 ggtggaataa tagatgcacg gaaaacagga gtcactagtg ctatgggaga gtatatagtt
      661 tttctagatg gtgatgattg gcttgcaaat acttatttag aaaaatatgc ggaagtaatt
      721 actaagtaca atccagatat aatatgtagt gggtattttg catcacgttc caacaaaatt
      781 agaaaaagag aattgtcttg ctcgtttgga tattatgaca aagataaaat tataaatttg
      841 atttatccta aattaattga ggatgaacat ggagagtatt ttagaccaca attatgggca
      901 aaagctttta gaactactct gtacaaggaa caacaacaag tatctgggca agttagtgtt
      961 ggtgaagatc atgcatgtac aaaaccatgt atttaccatg caaattcgat atatatgatg
     1021 gaaaaatgtt tatattatta cagaataaac gaaaattcta taacaaaaaa accacaacca
     1081 tattattggg aaggaccaaa ggctattgga gagcattttg aaaagcagat tgatatgaat
     1141 aagtatgatt ttcaagatca agtatataga aatgttacac acaatttatt taatgttgct
     1201 gtttcacaat ttaataaaca ggacaaatat ttaaatataa aaaaagatat tatacaaaat
     1261 ctaagtgacg aatactatac tagagctatt tgtaaatgca aatataaaga taattggaaa
     1321 ggaattagtg ctaagtttgc attgaaaaac aaatgggtat ttttaattta tatttataac
     1381 aaattgataa agaggtaata ataatgtcag ttaagattag tgtaattgta ccttgttata
     1441 atgttgaaaa atatattgat gagtgtataa atagtttgat aaatcaaaca ttgaaagata
     1501 ttgagattat tttgttaaac gatggttcaa cagataatac gttggcgata ttaaagaaat
     1561 atgaaaagct tgattctaga ataaaagttt acgaacataa aaatatgggg ttagggccaa
     1621 ctagaaatcg agggatcaaa atagctaatg gagaattttt ggcttttgtg gattctgatg
     1681 attttgtttc caatactatg tttgaaagtt tatataattg tgcaattgca gagaatgcgg
     1741 acattgcaat tggagaagta ggcatttttt ctgatagaga aatagaaaga gtaaaaataa
     1801 gaaaaagtct aacgaactta aaaacaattg aattagcaac atataacaag aaagaatttt
     1861 ttaagcaatt ctatttcaat cgtttatatt cacataatgc ttgggataag atatatagac
     1921 gtagtttagt attagagttt aatttatcat ttggtgataa caaaataatt tttgcagaag
     1981 ataattggtt tcaattacaa gtatttatga caaatacaag aatctgtttc gtagataaat
     2041 tgtgttatta ttatcgccaa caaaataatt ctataatgca taagccaaaa agtaatttgg
     2101 tttttagaca tggaaatatg attgctgatt atgaaaagtt gataaggcaa aatggaaaca
     2161 acataataga taaaaaagct tgtatgttgg ttgcatttga tgtactaatt atggagattt
     2221 ttaatcaaaa aaacgttggt ggaacatgtg aagattataa gaatgcatta gtttctttga
     2281 aacatcataa aatattgaga gaaaatattt caaatatagt tagaatgaaa gcatatgaac
     2341 ttgaacctaa tatgagaaag aagttagccc ttgtgaccat tagtataatg tttaatttta
     2401 aaatgtataa aacagcgtat aatatgctct ggagaatata taatcgataa agaggtagga
     2461 aatatgagga aattgacctt tgtgatagga attatgggaa aaggaggggc agaacgagta
     2521 attgcgaatt tggcaaataa ttttattcaa gataactggg aaattgatat tataactata
     2581 tatgggaatc ggcaagacta tgaactgaat agaaaaatac aggtacatcc aataatatgt
     2641 aaaagttcgt ttcgtgcatt tagacctttg gaacgcttta aggaacttag gaaaaaaata
     2701 agggaaatac agcctgatct ggttatttcg ttccttgctg atgtaaatat ccatgtcatt
     2761 atttcattgt taggagtaaa acaaaaatta attgtttctg aacgaaatga tccacaacgg
     2821 aatccagaag aaccatggat taggaaaatt agagattttc tttataaaaa tgtagatgga
     2881 attgtttttc aaacaccaga cgcaaaaaaa tattttagta agatcaatga taaaaaagta
     2941 aaaacaatta taattcccaa cccaataaag gaaaatttac cttattataa taaaactaca
     3001 agtagtaaaa aatttattac tgcatgtaga ttggataaac aaaaaaattt gcccttaatg
     3061 attgatgcaa taggaaaact tattcatgaa ggatatgagt gtgaactgga tatttatgga
     3121 gaagggggat taaaaaccga gcttgaaagt tatatcaacc ataatggatt aacagaattt
     3181 gttcatctaa aagaatttac aaataaaata catgaaaaga tgcaaaatgc ggcaggattt
     3241 gtaatttctt ctgattatga aggtatatct aattctatgt tagaagcact ggctattgga
     3301 gtgccagtta tcgctacaga ttgtccagta ggtggcgcaa gaatgtattt aggtgataga
     3361 aatgaaatag gtcatcttgt tgaatgtaat aatctagata agttaacaga tgcaatgcgt
     3421 agggtacttt tggatagaga aagtgtggta agaaaagcgc aaaaaggaat taaactaaga
     3481 aaagaactga catctaaaaa tatttcaaat atatggtacg aatatttaaa ccagttcttt
     3541 taaccaaaag gaggatattg tgtgaaagaa aaaataaata tattgatgtt ttcgttaacg
     3601 ttagtcgcgt ttacaatatt ttgcgctttt tcattaaatc agaactattg gctaaattgg
     3661 cttggaatat tgatttactt atatgcaatc tgtacatggc attggagaaa aggagattca
     3721 atattttcat tatacacgat ttttttcact ctttttttat tatttagtta tgggcaatgc
     3781 attatgtggg cattcggtat tggaacagat cgtggaatcg gtacaacagt agtagcttat
     3841 ggtacgggga ttattcctag tgaatcagat atgataatgg taaaatggta ttcttgtatt
     3901 tctatgtttg tatttcacat aggagcactc ttatttacga gaaaaaccac actaagaaaa
     3961 gttagttggt atgaatctgg agatgctgat gccgatagaa agtttttatt taaaataggg
     4021 tgtatcattt ctataatagt agtaccgata gtttttgttt ctaaattact agaggtacgt
     4081 atagcattag tccatggtta taatgcatta tattatggtg attatgctac acaaagtgga
     4141 tatttacaaa ttattctata tctttttttt ccagccttaa tatgtttatt aattggtagc
     4201 aacttttcaa aagtaataac gagatttgtt tttattattt ttgctttata ttctttatta
     4261 ggaattatgt caggagacag aggaagttgg ttgtatagct ctattatact catatgggca
     4321 tacactcaat ataaaggaac ctttaattat aaaaaattaa taaagtggct tattttagct
     4381 gttataggaa tatatattct aaacgtaata acgaaagcac gtgatggtgg aggactaagt
     4441 aaacttactt taaaagattt tacatctgta tttgattcag atgattctcc tttagttgat
     4501 tctttttttg aaatgggggg gactatgagt attataactt ttttcctaat aagtggtaat
     4561 ggaatatatc cctttgctaa tacttatttg acctcactct taggctctat atcaacaaga
     4621 atgctatcaa tgtttggaat aaagtttgtt ttattagctg attggttttc tcaggattat
     4681 ttaggaatca cttgggggac tggattctca atgattgcag aagcctatgt caatggtgga
     4741 tacattgggg gtatagtcta tatttttatt attggtatag tcatcggtaa aatcctttct
     4801 aatagtatag acaaccaaga tattgaaaat catcctatga agatgttttt ggctataact
     4861 acagcaaata ttataatggg ttttcctaga gctgcttcat atttaattgt gaaaaatttt
     4921 gtgtatggtg ttttaattat attgttgata aactttttcc tacagcaatt taataaacgt
     4981 ctttaatatt taagcttaat aaaaagataa aacaagtcag gagttgcaaa aatggaaaga
     5041 actgctcggc tcaaaaaaaa cactatttgg gctctggtgt ttcaaataac ttctattgtc
     5101 tgtggtatga tcttgctacg tttgatatta acaaagtacg gatccgaggt taatggaatg
     5161 attagctcta ttaaccaatt tctacaaatt atttcttttt tacaattagg agtaggcgct
     5221 gtaatgcaat caactctata caaaccacta gcagaaaagg ataatttaat gataagtcaa
     5281 atcttagctt ctggagggaa gttttatcgg caaattgcat atattctact agtatacgtg
     5341 ggtttgttac ttgcagtcta ttatgttctc gttcctaatg aatttgggag atcatataca
     5401 atggcaatga ttgcaacatt aagtattaat tcatttgctc aatattattt tggtattgtt
     5461 aatactttgt tattaagtgc tgaccagaaa atttatatta cgtatattgc acagacaata
     5521 gcatttattt ctaatacagt tgcatgtgct ttattaatta gtctgaacac agagatcctt
     5581 atggtaaaac ttattactgc tataatttat cttgcttgtc caatatatta tagatggtat
     5641 gtggatcgaa actataatat aaagaggaat gtgtcatatg ataaggaacc gatccctcaa
     5701 aaatggaatg gggttgcaca acacgtagct tctgttgtac tagatagtac tgatgttgta
     5761 gtgttatcta tattttctaa cctgatatat gtatctatat ataatgtgta caatttagta
     5821 atatacggag taaaacagct attcatggct atgacaaatg gcgttcaggc cttactaggg
     5881 gaactttggg tcagaaaaga aatagaagtt ctttacaaaa catttgcatg gttcgaatgg
     5941 attgtacata ctttgacagt ttttattttt ggctgtaccg gtatactaat cgttccattt
     6001 attcaagtat atacaagagg agtaacagat gctaattata atcaattatc attcgcagct
     6061 ttacttgtaa ctgctaacgc acttcactgt ctgcgtacac cttatcatgt aatgataaaa
     6121 gcagctggta aatataaaga aactcaaaat agttttataa ttgcttcttt gttaaattta
     6181 ggtttatcat taattttggt taaaccacta gggctagttg gagtagcatt aggatctcta
     6241 atttcaatca catatcatac actttggagt gcaaattata attcaaaata tttgcttaaa
     6301 tggccgatga aaaaattcta taaacagtta tttgtaaaca tcttaactgt agttctttct
     6361 tttggggcga catcacaatt gaaaatgatg tcaatcacat atttggattg gattgttctc
     6421 gcaattaaat gtgcagttat tgtatttata tgtataatcc tagttaatgt tttattttat
     6481 agaagatatg tagtaaaaat aattagtaaa atcatcgtaa aaataaagaa aatttaatac
     6541 acaataaatg ttttaataaa cttaataa
//
LOCUS       DACCVH010000116         6347 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.121, whole genome shotgun sequence.
ACCESSION   DACCVH010000116 DACCVH010000000
VERSION     DACCVH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.121"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            290..1135
                     /locus_tag="IVV98_002651"
     CDS             290..1135
                     /locus_tag="IVV98_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7808238.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="IVV98_002652"
     CDS             1416..2636
                     /locus_tag="IVV98_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP7808239.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="IVV98_002653"
     CDS             2633..5353
                     /locus_tag="IVV98_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7808240.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="IVV98_002654"
     CDS             5337..6281
                     /locus_tag="IVV98_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7808241.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2363 a          983 c         1224 g         1777 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttc
//
LOCUS       DACCVH010000117         6173 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.122, whole genome shotgun sequence.
ACCESSION   DACCVH010000117 DACCVH010000000
VERSION     DACCVH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.122"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            725..811
                     /locus_tag="IVV98_002655"
     CDS             725..811
                     /locus_tag="IVV98_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP7808242.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IVV98_002656"
     CDS             complement(932..1621)
                     /locus_tag="IVV98_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808243.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IVV98_002657"
     CDS             complement(1628..1906)
                     /locus_tag="IVV98_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808244.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IVV98_002658"
     CDS             complement(1866..2780)
                     /locus_tag="IVV98_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP7808245.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IVV98_002659"
     CDS             complement(2762..3142)
                     /locus_tag="IVV98_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP7808246.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="IVV98_002660"
     CDS             complement(3592..3879)
                     /locus_tag="IVV98_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7808247.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="IVV98_002661"
     CDS             complement(3899..4123)
                     /locus_tag="IVV98_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAP7808248.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="IVV98_002662"
     CDS             complement(4763..5296)
                     /locus_tag="IVV98_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP7808249.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="IVV98_002663"
     CDS             complement(5317..6159)
                     /locus_tag="IVV98_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP7808250.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DACCVH010000118         6095 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.123, whole genome shotgun sequence.
ACCESSION   DACCVH010000118 DACCVH010000000
VERSION     DACCVH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.123"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(460..2352)
                     /locus_tag="IVV98_002664"
     CDS             complement(460..2352)
                     /locus_tag="IVV98_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808251.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2349..4076)
                     /locus_tag="IVV98_002665"
     CDS             complement(2349..4076)
                     /locus_tag="IVV98_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808252.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4092..4742)
                     /locus_tag="IVV98_002666"
     CDS             complement(4092..4742)
                     /locus_tag="IVV98_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7808253.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4946..5242
                     /locus_tag="IVV98_002667"
     CDS             4946..5242
                     /locus_tag="IVV98_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7808254.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5434..6054
                     /locus_tag="IVV98_002668"
     CDS             5434..6054
                     /locus_tag="IVV98_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP7808255.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
BASE COUNT         1791 a         1240 c         1121 g         1943 t
ORIGIN      
        1 tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa aagtcgctta gtttcgagta
       61 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
      121 agaaactggc ttttgaacac cgtttaccaa gaggttgtga gcctgccgtt taactccgag
      181 tcacaaggag caatttcaaa aaacagcttc tcaggtttgt tgactattgt gacttgtgac
      241 cgaggagttg gcaggagaac accgtttaag gaagaggttg taaaatcagc ggtttgacct
      301 gagtattaga gatacaaaac ggaaaaatag cttctcatat tttgccgttt tttgagctaa
      361 taccgaagga cagctgattg aacaccgttt attcggaaaa agggactgtg acacgacttt
      421 tgtcacagcc cctaaaaaaa ataataaatt tgtactattc tatgaagctt cttcttcaga
      481 aaactgactg ttataaagat ctgcatagaa tccgtctttt tccatcaatg tatcgtggtt
      541 tcctgtttct acgatcgaac catgattcat cacaataatg ttgtctgcat cgcgtattgt
      601 agacaagcgg tgagcaacaa cgaaacttgt ccggttttcc aataggcggt tcatcgcttt
      661 ttgaatcagt atttctgttc gtgtatctac actagatgtt gcttcatcaa ggatcaggac
      721 atctggattt gctaagaatg cccgcgcaat tgtgattagc tgacgctgcc cttgcgaaat
      781 attgcttgca tcctcgttta atacagtgtt atatccttct ggcaatttac gaacaaaatc
      841 gtctacgtga gcagctttag cagcctcaat gatttgttcg tctgttgcat cgtcgttccc
      901 atatttgata ttgtcataga tacttcctgt aaacagccaa gtatcttgca gtaccattga
      961 aaactgtgcg cgcaattcat cacgtgaaag atcacgggta tctacaccat cgtaacgaat
     1021 actacctcca gaaacatcgt agaaccgttc aagaaggttg atcagtgtcg tcttccctgc
     1081 accagtcgga cctacaatag cgaccatctc accaggtttg acatccaagt taaaatcagt
     1141 cattagcaag ttatctggtg tgtagccgaa ttgaacattt tcaaaacgaa ctttgtatgg
     1201 tgtatctttt tcttctggaa ggccagattt ttcattggac atctcttctt catccaacac
     1261 ttcaaatacc cgttcggctg aagcaactgt tgattggata gtgttcatca aacttgcaag
     1321 ttgagtgatt ggttgagaga actgtgttgt atattgcaag aacgcttgaa catcccctaa
     1381 tgtcatgttc ccatttgcaa cttttactcc gcctagtaca gcgacgaaca catagcctag
     1441 atttttaacg aaattcatca acggcatgat gattgccgaa ataaattgag ctttccaacc
     1501 agcggcatac agattctgat tttctttttc aaatacttcc tggtcttttt cagtatgatt
     1561 gaatgtttta acaatggtat gaccaccata tgtttcttct acttggttat tcaataaacc
     1621 taaacttttt tgctgatctg cgaaaaacac ttgtgatttc ggcgctacga tcatcacgat
     1681 gatcaagctt aaagggatca tcaataacgc gactaacgtc aattgccagc tgattgaaag
     1741 catcatcacg atgaccccaa tcaatgtgac tgcactagtt acaaattgag tcaaattttg
     1801 ctgcagcgtg cttgcgatgt tatccatatc attgattgct cgagacatga tatccccatt
     1861 tgtatgtgta tcataatagg aaatcggtac acgattcatt ttggcttcca aatcatgacg
     1921 taattcataa actgttcgtt gggaaacacg tgtcataata aattgctgta aaaagttgaa
     1981 tacagcagaa atcaaataca tcacgattac tgtcgcaatg atctgcgcga ttttatcaaa
     2041 gtctatcgga aattttgtta cttgttggcc ttgttgcatc tgttgagcgc cagccattac
     2101 acctttgaat atttctgtgg ttgctttccc caagaccttt ggtgtttgga tttggaagat
     2161 cacggctgct attgctagta caaatacagc gatgatcgca accatacgtt tagacatata
     2221 gccaaacaat cggcgtaccg ttccccagaa atttttaggc ttttcacctt ttacaccgag
     2281 atttctgcca ggtccaccat gtcctggacc gcctgctggt ccatgagagg gacgtgtgtt
     2341 tgttttactc atgctaagtc ctcctctctt agttgtgaat gaacgatttc ttgataagtt
     2401 tcgtttgttg ctaatagttc ttcatgtgtt cctttgccaa ccagttttcc ttcatctagc
     2461 acaaggatca tatctgcatc cattactgta cttactcgtt gagcaactaa aacggtgata
     2521 ctttctttca tattcgtttt caatgcttgg cgaagattgg catccgtttt gaaatccaac
     2581 gctgagaagg aatcatcaaa cacatagata tctgctgttt tgactaatgc ccgtgcaatt
     2641 gccagacgct gtctttgtcc accagagaag tttcctcctc cttgttccac atggctatct
     2701 aagccatctt ccatctctga aacaaaatct ttagcttgtg cgatttctaa tgctttccaa
     2761 atcatttcat ctgttgcatc cggcttacca tactgcatat tgtctcggat cgttccagag
     2821 aacagaactg ctttttgagg aacaaagccc attaattctc gcaaattata ttgagtcatg
     2881 tcactaatgt ccgttccatt tatttggatc gaaccagatt cgatgtcata taatcgaggg
     2941 atcaaattga ctaaggtcgt tttacctgaa ccagtccccc ctatgattgc gacgatctcg
     3001 cccgacttgg cttggaaatc aatatcttcc aatgcaagtt tttctgctcc atgatatcga
     3061 taattgacat gattgaaggc caatgttgcg ttttttccag caaaagaaac tgttttagga
     3121 ttttcagggt catggatacc gattttttca tccaacactt cattaatacg gtcagctgaa
     3181 gcttgtgcac gaggcaccat gataaaaata gcggaaagca tcataaagct gatcaagatc
     3241 tgcatcgcat aagtcataaa tgcaatcaga ttaccgactt ccaaagtcat atctgctatg
     3301 tagtgtccac caaaccaagt gattgctacg tttgtaccgc tcatgatcaa tgtcatcatt
     3361 ggcatcatca atgcgacgat cgtattaact ttgattgccg tatttgtata atctttattc
     3421 gctaaatcaa aacgattttc ttcaaagcgt gtcttatcga atgctcgaat cactctgacc
     3481 cctgtcaatc cttctcgaaa taccaggttt aaacggtcag ttttcttttg catacttttg
     3541 aataatggaa cagcaaagta catgattccg ccgatcaaaa taatcattac tgggatgaca
     3601 actaagaaga tttttgtcaa ctgatgatct ttttgataag caagtatgct cgcgccaatc
     3661 aacgtgattg gtgcattgat catcatacgt aaaaacattt gtgtaaccat ttggatttga
     3721 gtcacatcat tggtcgttct tgtgatcaaa gaggccgttc catatttatc aaacgcatct
     3781 tttgtcagac tctctgattt tttatagaca tccgtacgca attgcttacc cagtttctgt
     3841 gattcacgag tagcaaaaaa tgtatttgcg atagcagcta agatactgat caaagaaaag
     3901 ccgatcatca caaaacctgt atgccaaata taatcgacat ctccttgcgc taccccttta
     3961 tcaataatat tggaggtaag tgtcggcaaa tataaatctg ccagtacttg gatcaccatg
     4021 aaaactgcag ctgcaattgc tgaagtcaag gagatccgtt ttacgatttt tagcatctag
     4081 ttcccttctt tctatttata tactccgttt ttcagccaag aaagtttcaa attgaattca
     4141 ctgattgctt gctctactga gtaatcttca gatgttgaaa ataagcgata cgaatgcgca
     4201 attgttgtaa atacagtatt catcactaat tggatcagta attccaattc atgatcattt
     4261 tttactttca gcttcgtccg atcgatcaat tcaagcaact cttttgcatc ttgtttgtgt
     4321 tctttatgtg gatcgtgagg cgttttttgg cgactcgtat gaggagcgac ttttcttgag
     4381 gcacggtaat ccatgttcat aaacaagtta cgataaaaag aagcattctc gccttccaaa
     4441 atctcataaa tcattttaga aaaataggat tcgaatcctt tgaatagatc accatcggat
     4501 tctttcatta gttgtaacat atctttagag ctgtcacgtc tcattgtctc aaagtaataa
     4561 aaataaagat cctctttatc ttcaaaatac tgatagaaac tgcctctagg gatatccgct
     4621 aatttgacga tattagcaat cgaagcttct tttaagggta ctctagaaaa ctcgattctc
     4681 gcagcctcga ttagtctttt ttgtttttct ttaggcaaat ggaaaaatgt ctgtgtcggc
     4741 atatggattc tcctttcttt caagatgaca cattgtcata tgacgctatg tcattataac
     4801 acctcctacc tgttttgcaa gacatttgca tagttttttt cattatcatc cgatacatta
     4861 aaaaagtgat aagaggaatc cttccatttg aattaatgag agttgcccat taaaatagcc
     4921 acatactaaa caaaggatga gataaatggc ccaatcaatt agtgtccaag acttcaataa
     4981 attgcctctc gatgctgaca gcatcgtttt agatacaaga aataccttag attacacaaa
     5041 aaaccactta agccactcgc tttctatccc cgctgctatc ttgccaagac aattaaaaaa
     5101 tctagatcca aagaaacttt attatattct aagctataca ggcaggcgat cagaagcatt
     5161 agccgatcaa cttactgcta atggttttcg tgctgtttat atcattggtg ggatggaagc
     5221 tcttcagtcg agtgttgctt gaatattgct tgttagattc aaaagaggct gtgacaaaaa
     5281 atcgtgtcac agcctctttt ataccctgtc tttttttagt tatttattct tcaaccttat
     5341 caatatgact tgatagcctt ttctttttcg agtaaactga ttttgttagt catagttata
     5401 acaatcatag caataaaagg agaaggtaag catatggcat ctgttttagt agtcaaaggt
     5461 catcccctaa ctgcagaaga atcgcgcaca gttaaggcat tgacgtcttt tttaacaagt
     5521 tataaagaaa atcatccaga tgatgaagtg actgttttgg aactttatcg cgatgatatt
     5581 ccggaaatcg atgaagaatt attatcaggt tgggaagcat tacgtgctgg tgcagaattc
     5641 acttccttat cagaaagtca acaacaaaaa attgctcgtt tcaatgaatt gactgatcag
     5701 ttccttgctg ctgataaaat cgttatcgca aacgccttat ggaatctaaa tatcccaaca
     5761 aaattaaaag cttggttcga taccgtcaat gtagctggaa aaacgttccg ctatacagaa
     5821 aacgggccag aaggattagt gacaggtaaa aaagcactgc acatccaatc taatggcggt
     5881 gtatacaacg gacaagactt tgcctctcaa tatgtaaaag gtattttaaa ctttgtaggc
     5941 atcgatcaag tagatcagct attcatcgaa ggaatcgatt atgaccctga ccgtgcagat
     6001 gagttgatgc aaaatgcatt agataaagct gctgctttag gtaaatcatt ttaaaaattg
     6061 agataaatgc atacaaaaga gacagaggaa aaaat
//
LOCUS       DACCVH010000119         6072 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.124, whole genome shotgun sequence.
ACCESSION   DACCVH010000119 DACCVH010000000
VERSION     DACCVH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.124"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(76..606)
                     /locus_tag="IVV98_002669"
     CDS             complement(76..606)
                     /locus_tag="IVV98_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7808256.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(788..1444)
                     /locus_tag="IVV98_002670"
     CDS             complement(788..1444)
                     /locus_tag="IVV98_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAP7808257.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1571..2044)
                     /gene="dfrF"
                     /locus_tag="IVV98_002671"
     CDS             complement(1571..2044)
                     /gene="dfrF"
                     /locus_tag="IVV98_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAP7808258.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2439..3830)
                     /gene="amt"
                     /locus_tag="IVV98_002672"
     CDS             complement(2439..3830)
                     /gene="amt"
                     /locus_tag="IVV98_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP7808259.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGFLAMTISMVVSLYEYPTFATSGFSLVFFLLLGGLLWFIPVALCAAEMATV
                     KGWEKGVSQTKRY"
     gene            complement(4171..4413)
                     /locus_tag="IVV98_002673"
     CDS             complement(4171..4413)
                     /locus_tag="IVV98_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7808260.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4445..5002)
                     /locus_tag="IVV98_002674"
     CDS             complement(4445..5002)
                     /locus_tag="IVV98_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7808261.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5015..5203)
                     /locus_tag="IVV98_002675"
     CDS             complement(5015..5203)
                     /locus_tag="IVV98_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP7808262.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5216..5782)
                     /gene="amaP"
                     /locus_tag="IVV98_002676"
     CDS             complement(5216..5782)
                     /gene="amaP"
                     /locus_tag="IVV98_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP7808263.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         1828 a         1276 c          892 g         2076 t
ORIGIN      
        1 aaaaatctta aggattttcc cgccaacgtg gtcggatcgc tccgtcggtt taacagcttt
       61 tctgtttctc tctagttatc tacgcatata aatcaaatcg gttattccgt tataagtctg
      121 tgttttacaa agccttaact ttatttccct gtctatgttg cccaaaagac gaaccccatt
      181 tcctaacaga gtaggaataa cagaaatgta atatttatca atcatatttt tgcttaccaa
      241 ctgctgaaca agatttgctc cgccacaaat ccaaatatcc tttcctgctt cttgttttag
      301 ccgttccaat aataaaacag gattttcact tgtaaaatga atttgttggg aagaattgca
      361 ctctttatgt gttaatacat aagttgtaaa tttattatat acccattctt gcggagaaag
      421 ttcagtaaca acctgatgag aagtattcca ccccattaag acagtatcta tatctttggt
      481 aaattctgta taagtgtcga tgttttcatt gtcatttcca tgaccattta gccaagctac
      541 tccaccatta ccgtccgcaa tatatccgtc aaggctcatg gcaataaata aaactacttt
      601 tctcattttt tctcttttat aaatacaaac aggaatttat ttctcttttt tactcataag
      661 ggaacaactg attgctacaa ataaacccat taaaatccat ggaaatgctg ctcttataaa
      721 atcactaacc atactttatt cctccttaaa ttccaatttc cttagttcta caaactgaaa
      781 tttttgccta tgaatgtatc ttgttcttta tacgcaaaca ggcttctgtg tgcataatcc
      841 aatgtcttga aaacggcatt tgaattagtc cacaaatatc tttattacac caataatcaa
      901 tcagccaaat tgctttttca ttgtcgttta ctacattcaa cgattctaag tatccttttc
      961 tttctttcgg tatttttctt ttcaattcat cataagataa ccgttcaagc attttctcag
     1021 tgctttccca tacttcgaaa atatataaat ataattcttc cagattaagc tgttttgaaa
     1081 agtctgcaat ctgctgtttc atgagttcat ttcctgttgt aatgataggt gaattgatac
     1141 gctcttgata attgcctgca aaaaatactt gttcatcttc atttatcact gtatgcacaa
     1201 ctatatcttc aatgcggaaa atatgccaaa tagaataagc aatcgtctta ctatgataac
     1261 catcagcgtt tatgaagggg attgagttaa aatcttctct gcataattct tctttgaaag
     1321 atactaaggt ttgtattaac tgacttcgta aagtaagtaa agtatcaata cccctcttat
     1381 aagtatcttt cttttttatt tgtgcctgca ttgttttatt aagttcagac cattccttat
     1441 tcatattcaa tcctctctca aattctgatt ttatcgcccc atacaaactg gaatttgtct
     1501 tacaacaatt tatatatgca taaaaagcaa tatatttatg aaaacaccct aaatccaaaa
     1561 tttactcaat tcattttttc cttacataaa atgttctcgt atatttcact tcctcaccaa
     1621 gtgtttcccc tatcaaaact tcaaaatcat tgatatcaaa ttctggaaag aatgtatctc
     1681 catcttcaat atttaaatct acttctgtga tatacatttt atctactatt tgcaaagctt
     1741 ccttaaatag tccatatcca ccagatatgt atacatctcg tcctttagcc aataataatg
     1801 catcttctaa tgatttaact gaaactaaat tatctccttg atactctgtt gtggtggaaa
     1861 caacaatatt cattctatta ggcaacggat gaccgatttc ttcataagac tttcgcccca
     1921 taataaccac attacccgtt gttaactctc taaattgctt ttgttctccc tttattttcc
     1981 atggtatatt accattcttg cctataacat tattctttga cctcgcaaca atcaaaccta
     2041 tcatctattt catcctccat aatatgatgt cgtacctgtg attccatcaa gtgcaccaca
     2101 tcttaacaaa ctcaaaatta tctcgaacta accagctcga caaattcctt ttttgtcttc
     2161 atctgcatta tatcatattg ttataagcat tgccatttct tttctgcttt tgaaaagtta
     2221 cttatcagcc tatgttttgt aaagggtgat attcagcatt tctcacgcaa caagcccttg
     2281 acaaaccata gactaataag ttttaaggta atcaagcaga aatgaaatag tctgctgttt
     2341 cacggcaaca aaaaagagat accaacacac ttatgtagta tctcttagtc tagtagcaat
     2401 attcttttgt ttgcaagcag gtaaacatgg gctgtttctt aatatctttt tgtttgggaa
     2461 acaccttttt cccatccttt caccgttgcc atctctgctg cgcacaatgc cacagggata
     2521 aaccatagca aaccgcctaa taacaagaaa aatactaagc tgaagcctga ggtcgcgaat
     2581 gtgggatatt catataatga aacgaccatt gagatggtca tagccaaaaa gccaaagaag
     2641 aaaaagtcca atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc
     2701 gccgatttta aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca
     2761 atcacttgaa tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat
     2821 gcaaagatcc ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca
     2881 tcaagtgcat catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata
     2941 cccgcaatga tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta
     3001 atggctgcca atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct
     3061 tttacttttg caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa
     3121 ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac
     3181 cagccaaacc aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt
     3241 ctttctccta aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat
     3301 ccagctgtcg tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa
     3361 aatccgccac cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata
     3421 acaagtataa tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga
     3481 acggtaatca cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca
     3541 ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt
     3601 ccaataacac cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata
     3661 atcgttgtta tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc
     3721 cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta
     3781 cataaaatca tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc
     3841 tcctttctac gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg
     3901 aattaatact tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct
     3961 ttttcgtttt tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg
     4021 tttattttcg tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc
     4081 atataaaata tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt
     4141 catttcaaca taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac
     4201 taatactaaa atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg
     4261 tccccaagtt cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt
     4321 tgcgatgatc cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat
     4381 accgccgacg attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta
     4441 cttcttattg tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag
     4501 cagattttgc tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg
     4561 ttactttgtc ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg
     4621 caacattcac attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga
     4681 tcaattcttt gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat
     4741 ctagatccac agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat
     4801 ctgtgttgac taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac
     4861 catctacatc tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca
     4921 attcaccatt catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg
     4981 tattcatgtt tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta
     5041 ttcctgactg tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca
     5101 acaatgtctt gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc
     5161 caaagataat agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt
     5221 ccactcgaga gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga
     5281 ctgccacttt gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt
     5341 gcatcaatac acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat
     5401 ggatatggat tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt
     5461 cttcgtgtaa atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc
     5521 catcttcccg tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca
     5581 agatgataat agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt
     5641 agtaattcgt taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg
     5701 cattgatcaa cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga
     5761 ttatttttaa ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata
     5821 actctaccga caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc
     5881 gctaccaaac attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca
     5941 attgcttact tattctctat ttacttttga ttgctggcta tacttaaagg atattattca
     6001 agattaaaaa ttgcaaagat tatgctcagt tattattaca agattctatt tatttattaa
     6061 attttttcgg ag
//
LOCUS       DACCVH010000120         6005 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.125, whole genome shotgun sequence.
ACCESSION   DACCVH010000120 DACCVH010000000
VERSION     DACCVH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.125"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..450)
                     /locus_tag="IVV98_002677"
     CDS             complement(<1..450)
                     /locus_tag="IVV98_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7808264.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="IVV98_002678"
     CDS             674..1465
                     /locus_tag="IVV98_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7808265.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="IVV98_002679"
     CDS             1431..2384
                     /locus_tag="IVV98_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HAP7808266.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="IVV98_002680"
     CDS             complement(2782..3756)
                     /locus_tag="IVV98_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7808267.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="IVV98_002681"
     CDS             3871..4305
                     /locus_tag="IVV98_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7808268.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5416)
                     /locus_tag="IVV98_002682"
     CDS             complement(4430..5416)
                     /locus_tag="IVV98_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HAP7808269.1"
                     /translation="MEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGAFFRVHHFAPQIG
                     SPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQGRVQLGVGRGSPE
                     QVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPMFPQGSGKLRIEP
                     YSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQQANQLRAYKEAW
                     KQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYHRNPTIFGKTFAG
                     EPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIAPELGWR"
     gene            5844..>6005
                     /locus_tag="IVV98_002683"
     CDS             5844..>6005
                     /locus_tag="IVV98_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HAP7808270.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAED"
BASE COUNT         1892 a         1132 c         1035 g         1946 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaaa ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcgag acacatggct tgaatccaag agctataaaa atcatggcag
     6001 aagac
//
LOCUS       DACCVH010000121         5988 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.126, whole genome shotgun sequence.
ACCESSION   DACCVH010000121 DACCVH010000000
VERSION     DACCVH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.126"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            59..415
                     /locus_tag="IVV98_002684"
     CDS             59..415
                     /locus_tag="IVV98_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7808271.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            405..671
                     /locus_tag="IVV98_002685"
     CDS             405..671
                     /locus_tag="IVV98_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7808272.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            830..1831
                     /locus_tag="IVV98_002686"
     CDS             830..1831
                     /locus_tag="IVV98_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP7808273.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2201..2815)
                     /locus_tag="IVV98_002687"
                     /pseudo
     CDS             complement(2201..2815)
                     /locus_tag="IVV98_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3055..3300
                     /locus_tag="IVV98_002688"
     CDS             3055..3300
                     /locus_tag="IVV98_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808274.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            3398..3619
                     /locus_tag="IVV98_002689"
     CDS             3398..3619
                     /locus_tag="IVV98_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808275.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            3941..4621
                     /locus_tag="IVV98_002690"
                     /pseudo
     CDS             3941..4621
                     /locus_tag="IVV98_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            4683..5300
                     /locus_tag="IVV98_002691"
     CDS             4683..5300
                     /locus_tag="IVV98_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808276.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT         2206 a          820 c         1071 g         1891 t
ORIGIN      
        1 aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat aattgggtat
       61 ggaaaaaata tcttttgaaa catttaaaag acctaatggt catgatgaat ttttagaatg
      121 gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag aagaaacaga
      181 aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag acactaattt
      241 gtacgaatta agaagtaagg taggatcaaa catccaaaga gctatctatt tccatgtggt
      301 caatggaagg tatgtcatta cccatggatt tactaaaaaa acggagaaaa caccaataag
      361 tgaacttaaa catgcaaaag aacttagaga ggagtggttc acaaatgatg attaaaaaat
      421 tgattgaaga aaagcaaaaa gacaaagatt ttgcagaagc atatgaccgt gaaggaagaa
      481 aactcgaaac tgcggttgct ctttatcatg cacgggagga agcaggccta actcaagcgg
      541 agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag agaggggata
      601 acgtatcttt cgataaactt gatgatatcg ctagggcatt aggcaaaaag ctggtagtag
      661 aatttgctta aaagcgagtt gaaaatatac ctgtaatagg ctcctaacta atcaattagt
      721 ttagtgggcc tttttgtact aaatagataa aagttgtcct atagtgtaaa agtcaataaa
      781 ttttatacaa aaattacttt aaagagacat aaagagaaag gtacaataaa tgaaaaccat
      841 aaatctaata aaagtattta tagcatcacc aggtgatata gcagcaaaga ggaatgaagt
      901 agaagaaacc atatatagat ggaatataga aaatacagat aatacaaaag taattttgat
      961 gccaattcga tgggaaacga atgcgattcc tacttatata aataatagct ctgggcaaag
     1021 tgttattaat aaacaaattg tagaaaatag tgatatatta ttagcgattt ttggccataa
     1081 gttgggttct ccagttgata attatagatc gggaactata gcagaaattg attactttta
     1141 taaaaatagc aaaggcgagg taggggtttt tttcttagat gaaccagttc cacaagtttt
     1201 ggctgaagag tatatagaag ttaagaagta cagggactct ttagaagata agggttttta
     1261 tggaacatat agcaaagaca atatcagaag gtttctcaca aaaaaagtga attatttaat
     1321 tgagaaagca caaaataatt tagaatcaaa acgctttgat ttagattcta tttcttacaa
     1381 gacaccttca gtaattaaca aaaaagttac cggaactgat aaagattttg atgacaactt
     1441 agatattttt gatccaatag aatttgacaa tgatgaaaga ttgctgctaa tatatgcgtt
     1501 tatggatgaa aattctatct tttcaactga taattcaact tatagaaaag tagttcaatg
     1561 ggaaagtgat aacaatttaa ggagttactt gagtgataga gtatttgatg tactagaaaa
     1621 attaagtaaa tcgggaattt taaaggaaga atacgattct tcttttgatg agtatccatc
     1681 acgctatatt ttgatttcag aggactataa gaaatttaaa aggtattttt taaaaaatga
     1741 aaaaaagata tctgttatta tggagaaata caaagctcca atacaggctg atccattttc
     1801 caatttggat gaatcagatt taccgtttta aattttaaat agataatttc attttttagt
     1861 agcagaggta taaacttttt taatgtttga attgaaaaga aatgctaata ggtcgacttt
     1921 atgtttctct tgtgcaatcg taaatgcggg ggaccataaa attgatctat tatcgagtgt
     1981 gtataaaata aaattcaaat cttattagtt tacataagat acattatact aagttgtcaa
     2041 tgttaaatgc ctttaaataa ggacgattta tgcatcaatt atatttatgt taactaaatt
     2101 ctttttaaca taaatgtaat caacttagct agatgaatct aaaatgattg tctgtattga
     2161 tgacaaagct aattaataat tacgtgattc aaaaaagaaa tcatacaatt agttggtcga
     2221 tttctttttt tattcggtaa attgtttgcc tagtcacatt gtagtctgtt gcaatctttg
     2281 agatagcaac cccattctca agatcctgaa cgatactcct atagacaagg cgacgttgag
     2341 gatctttggt gtctgcactg tataacttag gacgaccttt atagacgccg tttgctttag
     2401 cgattttaat tccttgtgcc tggcgtcgtt tcgattcagt acgttcttgt tcagcaatca
     2461 tggctgagat ttaaatgatt aagtctttga tgaatttatc taggagagga tttccaattg
     2521 cttcagccat gatcggtaaa ctggtgataa taagtcgcac attcttcttc tttagataat
     2581 tcactgaatc gataatctcg tcataattgc gtccaagtcg atcaatggct tctacaataa
     2641 aaatatcttg ctctctgaca aaatctaaag cttcctggaa aatcggccga tgactaatcg
     2701 tcgctccaga ttgtttttcg ataaaaattt tttcagcgcc aaactttttc atttcttcaa
     2761 tttgacgttg ttcattttga tcgatggatg aaactctaat ataagcaatt ttcaaattta
     2821 ttccctactt ttctataacg tttataatac accctaatca tacgttagaa ctctaaattt
     2881 ttcaatgtta tatttttgtc tatttagggt aaactctaaa tagacaaacg gtttttgaat
     2941 tctaaaagtt aaatagttta taatagaaga aaaagaatgg ggtgacgatt tcttagattg
     3001 aaaaggaaag ataaatatta tagattatta cttttgacag ctgaagcagg atggatggat
     3061 tttccagaag ttgtaaaaga agttcaagag ataggtgcaa ctatttctga tagccgctcc
     3121 tctcctatga actatcagga tgcccatgga attaaaataa ttgatcaaga gagaaatgtc
     3181 agaaaataca caacaataaa tgagtgtgta attaatgaaa atctttgtag ggcaccgata
     3241 acgaaacaca ttaagaatag aagcaaagca aaagacggaa gaacttttac taccttctaa
     3301 gtttttttca tatttgtttg ctatacttag atctaaggaa ttagactttc gctgcccatt
     3361 atttaagttt gaggtagcgt cttgcgaggg atcaataatg gaagaagaaa aaatatttga
     3421 aaaacgctgg gaattggctt cagttgaaca aagagcaagg taccataatc taatgtcctc
     3481 ttaccgtaat attgattgga cttacaaaga aaagaagtac ttgctttggt tatgtcagtt
     3541 agatgtaaat acctttgaaa catttgaagt gattctagat aagattaaaa acagcaatga
     3601 aaaaagagct gatctataat ggttcgctct ttttatttta ttaactcttt ggttactata
     3661 tgtaaaatac agcttcatat tacaataaat ttcaggatac aaatttattt aagcatatat
     3721 aaatataatt gaaataggac ataaatatat gagtatgaga aaggtgattc catgtttaat
     3781 aaatgggcaa accacccaat gaactcgaga ggtagagata atttgaagga gacggacaag
     3841 ttctgggaag aagtatatag taaaaacggt tctgttgcaa agttttccaa aaaatctatt
     3901 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
     3961 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
     4021 ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc atactacgat
     4081 ttatcgttgg gtataagagt acagcaaagt cctctattat ctttggaaga agaaaaatag
     4141 acaatccttc tattcatgga aaatggacga aacctatatc aaaattaagg gacgttggca
     4201 ttatctttat cgtgcaattg atgcggacgg cttaacctta gatatctggt tacgaaagaa
     4261 acgggatacg caagcagcct atgctttctt aaaacgactc cataaacagt ttggtgagcc
     4321 gaaagcaatt gtgaccgata aagcaccttc tcttggctcc gcctttagaa agttacagag
     4381 tgtgggttta tatactaaga cagagcaccg aactgtgaag tatcttaaca atttaataga
     4441 acaagaccat cgacctatta aacgacgaaa taaattttat caaagtctcc gtacagcctc
     4501 ttccacgatt aagggcatgg agaccattcg aggaatatat aaaaagaacc gaagaaatgg
     4561 aacgctcttc ggcttttcgg tgtctactga aatcaaggta ttaatgggaa taacagccta
     4621 agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca gaaccgagaa
     4681 ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt ttaaagtgga
     4741 aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt atttttactg
     4801 tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa ggtcgtttag
     4861 ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc ctatatgact
     4921 atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa gtaaaagttg
     4981 gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc tatacagtag
     5041 aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga acagttgtga
     5101 aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct attaaaggta
     5161 cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg attctatctt
     5221 tattaattag ttcaataact tttatattct tatttacacg ttatttaata agatgctgcg
     5281 gtgaaatgaa aatagattag atagatatta taaatatgtt gattctattt tcatagcaat
     5341 ggagaaaata cattagcaat atataaaaga aggtatcaag agtcacagtg aatttattcc
     5401 gaaaagtgaa aagagcaaat ataaaattta atgaaaatat agaactaaat aggaaaacgt
     5461 agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa aattatataa
     5521 actaatttag tgttttgttt gtaattccta attttgctcc acttttagat aatttttagg
     5581 tctatttaac tcatcagaca ttctatgctc atttttctcc aaatttgttt caactctttc
     5641 gtacttaatt ttgcgtattt gaaaattctt cttttagagt acttttatta cgatactagt
     5701 atgatatata tctatagcaa acagttaaaa tcttcctaaa ataagcgaat agcattccta
     5761 aaacctataa aatttttaga tgaagcgaca agtggacaat taataaacta cttgaacatg
     5821 aaattatgga tcacctttca aatttagaaa atggaattct tatacttatt gcgcaacatt
     5881 tattgattgc aaaattatgt gacaaaaaaa actagtagaa gaaagaataa tggcttgata
     5941 ataaagtact acctattaaa ggtagtactt tatttaattt agtataaa
//
LOCUS       DACCVH010000122         5866 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.127, whole genome shotgun sequence.
ACCESSION   DACCVH010000122 DACCVH010000000
VERSION     DACCVH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.127"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            190..1086
                     /locus_tag="IVV98_002692"
     CDS             190..1086
                     /locus_tag="IVV98_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP7808277.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1236..2177)
                     /locus_tag="IVV98_002693"
     CDS             complement(1236..2177)
                     /locus_tag="IVV98_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP7808278.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2303..3424
                     /locus_tag="IVV98_002694"
     CDS             2303..3424
                     /locus_tag="IVV98_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7808279.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3682..5184
                     /locus_tag="IVV98_002695"
     CDS             3682..5184
                     /locus_tag="IVV98_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP7808280.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5251..5778
                     /locus_tag="IVV98_002696"
     CDS             5251..5778
                     /locus_tag="IVV98_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7808281.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1923 a         1035 c         1228 g         1680 t
ORIGIN      
        1 acaaattttc agacaattac aactattcag aaaactttta ggcgaatttt aatagaagaa
       61 tgatttattt catcatattt tcatacaaat gttaaatttt catacaaata taggaaacgt
      121 tttactggct ttttactatt taaacaggct atcataggaa aaagtgacag agaaagtgag
      181 gcggaaaaga tgaacaaaaa tgacgtactg ctagttgcaa aaaataaatc actttatttt
      241 ttgccttcca tccgctcttt agatgtttgg tccggaaaag atttactaca gtcggaattc
      301 attaaatcag ctagacaaca gttggcaaat tatcagctga tcgttttttt agattatgga
      361 tttgatatgg agatggctcg acgcgtgcgc ccatttacca atgcaaaaat tgtgttattt
      421 ttttggaatc acttcaaagc agaacacgag gcgatgctga agcaggcaca agatgaaccg
      481 gcaatcgatg agatttatca ttttgatttt ttggaagcaa aagaacttgg gctgaaacat
      541 aatagttcat tttattcgaa acatatgaat ttttcttcta gcgaaccaaa gacggatcta
      601 ttttttggtg caacgaataa tgggagaaaa gaacgagcag aaagctataa gcaggaattt
      661 ataaaaagag atgttacgac caactatttc attcttccac atcgagggaa tgaacaacct
      721 ggatatctta cttatgaaga gtacctgaaa aaaacagggg aatcgcgcgg gattctggaa
      781 ctgttgcggg agggtcagca aggagtgact ttgcggacat ttgaatccat gtattttcaa
      841 aagaaactag tgacggataa tcaagcgatt gctcattatc atttttatcg tcctgaaaat
      901 atttttttgc ttcgagaacg tgatttagat gaattaccgg aatttctgca tacaccattt
      961 aagccaatcc tatcagagct attggaattt tatgatgcag aaaattgggc aaaacgattt
     1021 atcactaacg attccactat ttatgagcaa tacgaatatg acctctcctc tgttgaaaac
     1081 aaataaaaaa cctacatttt gaagagatta tgtactgaaa caaacaagca caattcttat
     1141 ggcatcatga gagttgtgtt ttctttttga tcttttattg ggcttaaaaa aagagaacca
     1201 gctgctgatt cagctgattc tcatcagaga gccttttatt ctgcgccaag gattccttct
     1261 tttgcatgga ctaattgggt caaaaaggca caatatggtg tagcaatatc atatttttgt
     1321 ccttttcgcc aaatggcacc attgatgtag tcgatttcag tcaaacgatg gtttttgatc
     1381 aggtcttggt acatagatgg gtaatgcaac ccgatgttgt caggatcata agtagaagca
     1441 atatgttggt acacttcttc ttgatctagt atgattcctt cttttgctgc gatagaagca
     1501 aattcagata cgattgttcg aaccatgctc tctgccgctt tttgcgcgcc tagttcagca
     1561 atattacaat ccaaaatcgt gcataaacca ttcaatgttc catttacaca agcttttcgc
     1621 caaatggaat aacgaacgtt atggctatag atcggattta aatttgcttc ttgaaagact
     1681 tctacaactt tttttgtaaa tgcttcgcct tctggttcca agttctctag ttcgatttct
     1741 ccatcaccta acaatgtgac ttttccggga ccagctagac cagctgtcca catcgtgatc
     1801 ccaaataaga tatttttctt tggcacatat ttttccagta catcttcatg acctaatcca
     1861 tttagtaaac acaaaacata agtattgtca gtaataatgg attggatcga acaaaacata
     1921 tcatctaatt gattggcttt tgttaatgct acgatcaagt ccacgtgttc gttgctttcg
     1981 atgatttctt ctggtgaata gattggcagt tttgcgacca cttctttacc gttaaagtca
     2041 gcaatcaacc catttgtacg aatggcttca atgtgagcag gccaacgatc gatcaagagg
     2101 acctcatttc cgctttgatg tagcatcaat ccgattcggc tgcccattgc tccggcccca
     2161 gctattgcga ttttcatgtt ttttctctcc tttattcaat gagttccctt ttagtatata
     2221 gaaaaatgga agaaaatagc attgttttgt ttgaaaaaaa tgaaaaaaag tgtcttactt
     2281 aagaagaaag tgagggatac agatggatat tttggcggca attgattcat ttaaaggaag
     2341 tgcttcttca tttgaactaa atcaggcagt tctaaatggc tgggaagatc gtaaaggaag
     2401 aaaaatcaat gtgccgattg cagatggcgg agaaaatact gcagaagcaa tctattacgc
     2461 gctcagggga acatggcgta ccattgatgg gatggatctc ttattccgtc agcgaaaaat
     2521 cagctattta ttgacaactt ggcaaggaaa aaacaccgca gtcatcgaat ctgcacaagc
     2581 attggggtta gatctacttg ataaaccaac ggatcaaact atccgacttg cttccagtta
     2641 tgccttagga gaacttatta aagatgcact gcttcaagaa gtagaacaaa ttattgtcac
     2701 tttaggagga agcgggtgta gcgatggtgg tctaggatta ctccaatcct tgggtgcttc
     2761 tttagaaggg tacacagaag gaaatccttt attatctact aaaaaacttc attttgatcg
     2821 aagaaacgtt cttgtttcta aagtaaaatt gattatcgct gcagatgtta ccaatccata
     2881 tacaggtcaa caaggagctg cttggcaatt tggaagacaa aaaggaggaa tagatacgac
     2941 gctagctttc ttagataaac aagcaggaaa gattgctcag caaataaaag atttctggga
     3001 ggtggattta gatgatattc caggaagtgg agcagcaggc ggtattggtg gagccctttt
     3061 tttgttggga gcgaagatgg tttctggttt cgatttagtc agccaaatca ctggattgga
     3121 aaaaaagatc gaacaagcag atgtcatcat tacaggagaa gggcggatcg atcagcaaac
     3181 gatccacgga aaagttccat acggtgtagc agtgcttgca aaaaaatatc gaaaaccaat
     3241 aatcgctatt tgcggaagta gagaccaaga gctagaagga ctttctgatt ttctcccaat
     3301 tgtcttaagt attcatttgg gtccaatagg tttagaagaa gcaatggaac acaggcaaac
     3361 attagaaaaa acaaaaatct taggacagac acttagcaga tttttcacca tcctcccgaa
     3421 gtagttgaca aaatcatttt ctttatgcta tcgtaatttc aaatatagga caaagtgagg
     3481 gatccgtgca ttgaaaaatt aagtcgattg atgaaagctg cattcagact gtaccttgtg
     3541 gagacaagga agcagtgtgc agattttcgg gattggcttg gttttttcga tgtatgggtc
     3601 tttttgtgtg tatccaaccc ttgcatcctc tttagccagt tctgaaaata ggactggtct
     3661 ttttttacga ggtgatggaa aatgtctaaa atcgaaataa aaaatctgac attcggctac
     3721 gacagccaag gcacattatt atttgaacaa gcaaatctaa attttgacac acaatggaaa
     3781 ctaggactta tcggacgaaa cggtcgagga aagacaactt tactgaatat tctacaaaac
     3841 aaactacctt atcaagggca agtaatccat cagcaagaat ttgcctattt cccgcaacag
     3901 acaaaagata aagaacgttt aacctattac gtgttaaatg atattacgga ttttgagata
     3961 tgggaaatcg aaagagagct ccaattgatg caaacagatc ctgaaatctt atggagagaa
     4021 ttcagcacac tatcgggggg agagaagaca aaagtcctac tggcactttt atttgtggat
     4081 gacactcatt tcccgttaat cgatgaacca acgaatcatt tggatatctc tggtagaaaa
     4141 caagtagcgg cttatttgaa aaagaaaaaa caaggcttca tcgtggtcag ccatgaccgg
     4201 ggatttatcg atgaagtagt ggaccatgtt ttagcaatcg aaaaaagtca actggaactt
     4261 tatcaaggga atttctctat ctatgaagaa cagaaaaaac ttcgtgatga atttgaaatg
     4321 gctcaaaatg aaaaattgaa aaaagaagtc agtaggctaa agaaaacagc agctgaaaaa
     4381 gccgaatggt ctcgttcccg agaaggagat aaaacaaaga aacaagtcgg attcatcgat
     4441 actgaatcta gacgagtgaa taaaggagca gtgggtgctg atgctgcacg gacgatgaaa
     4501 cgatccaaag caatcgtgaa tcggatggag acccagatca gcgagaaaga aaaactatta
     4561 aaagatatcg aatatatcga ttctttgacg atgaatagcc aagcgtctca ccataagcga
     4621 cttttaagcg tagaagatct tcaattaggg tatgaaaatc tgttattcga gccaattcat
     4681 tttacaatcg agcctcatca gcgggtggcg atttcaggtc ctaacggtgc aggaaagtca
     4741 tccattatcc attatcttct gggggcattc aacggcaagg ttataggaga aaaataccag
     4801 ccaaaacatc tgagcattag ttatgcaagc caaaattatg aagacaatcg aggaacgttg
     4861 gcggaatttg cagagaaaaa ccaagtagac taccaagcat ttttgaacaa cctccgaaag
     4921 cttgggatgg aaagagatgt ttttcataac aagatcgagc agatgagtat gggccaacgg
     4981 aaaaaagtgg aattggctaa atctttatca cagccagctg aactatatac atgggatgaa
     5041 ccattgaatt atttggatgt cttcaatcaa gaacaattag aacaactgat cttgaacgtg
     5101 aaacctgcca tgttactagt ggaacatgat caaaccttcc tggataaagt atctactgag
     5161 attatttctc ttgagagaat ctaacccttg taatctcaag aacaacaagg tatggttaag
     5221 gggaactttg ccaacgaagg agagaatcac atgctttatg taacgagaca cggagaaaca
     5281 acttggaacg cacaaggatt agtttgcgga cgggcagatg tgccgctgac tgaaaaagga
     5341 cagatgcagg cacagaaact agcagaaaag gtagtagatt tgcctgttcc aatcacgaaa
     5401 atcatccatt cccctcttca acgagcaaga gatacagcac aagcagttgc tgatcgtctc
     5461 agcttgccgc tgaccgttga tgaacgattg gtagaaatgg attttgggga ttatgatgga
     5521 ctgccaagca aagatgagaa ctttcaaaaa gcacgtttag cgttcgctgt acgattccca
     5581 aatggggagt cagtcttaga tgtgtatgca cggatcgttc ctttattgaa agaatgcatc
     5641 gaagacgaag aaaatgtcta tctgttagtt tgccataatg ccttgataag agtgatcaat
     5701 gcttattttc atccgatgcc taatgagggg ttctttacat tcatggtaga taatacagaa
     5761 ttggtttctt atgagtaatt atgtttttgt gttatttaaa taaaatattt caaggcactg
     5821 cttttgctta gcagtgcctt ttttaggtta tgacaattct tttgat
//
LOCUS       DACCVH010000123         5779 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.128, whole genome shotgun sequence.
ACCESSION   DACCVH010000123 DACCVH010000000
VERSION     DACCVH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.128"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..813
                     /locus_tag="IVV98_002697"
     CDS             <1..813
                     /locus_tag="IVV98_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP7808282.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="IVV98_002698"
     CDS             807..1229
                     /locus_tag="IVV98_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808283.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="IVV98_002699"
     CDS             2363..3331
                     /locus_tag="IVV98_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7808284.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="IVV98_002700"
     CDS             3341..3829
                     /locus_tag="IVV98_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP7808285.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="IVV98_002701"
     CDS             4125..4406
                     /locus_tag="IVV98_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808286.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="IVV98_002702"
     CDS             4408..4824
                     /locus_tag="IVV98_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808287.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="IVV98_002703"
     CDS             5438..>5779
                     /locus_tag="IVV98_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP7808288.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2154 a          982 c          947 g         1696 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 acaggggcta cttggcatag tcgacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DACCVH010000124         5679 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.129, whole genome shotgun sequence.
ACCESSION   DACCVH010000124 DACCVH010000000
VERSION     DACCVH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.129"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(240..606)
                     /gene="ssrA"
                     /locus_tag="IVV98_002704"
     tmRNA           complement(240..606)
                     /gene="ssrA"
                     /locus_tag="IVV98_002704"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(777..1550)
                     /locus_tag="IVV98_002705"
     CDS             complement(777..1550)
                     /locus_tag="IVV98_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7808289.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1694..2044
                     /locus_tag="IVV98_002706"
     CDS             1694..2044
                     /locus_tag="IVV98_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP7808290.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2025..2741
                     /locus_tag="IVV98_002707"
     CDS             2025..2741
                     /locus_tag="IVV98_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7808291.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2741..4189
                     /locus_tag="IVV98_002708"
     CDS             2741..4189
                     /locus_tag="IVV98_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7808292.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4260..4769)
                     /locus_tag="IVV98_002709"
     CDS             complement(4260..4769)
                     /locus_tag="IVV98_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808293.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4759..5484)
                     /locus_tag="IVV98_002710"
     CDS             complement(4759..5484)
                     /locus_tag="IVV98_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808294.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1936 a          984 c         1120 g         1639 t
ORIGIN      
        1 gtttttcctt ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt
       61 ttgtaaagta ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt
      121 tttgaatgct attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa
      181 atgctcaaac ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac
      241 aatggagacg gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt
      301 catagtcaac tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc
      361 gctagtctga tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa
      421 gttaggaccc ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta
      481 ggcagctaaa gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt
      541 tacgtagacg taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac
      601 gtccccgtta gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat
      661 tgggataaat tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt
      721 tcttaagaaa aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa
      781 atcagatcaa aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata
      841 aaggtagaaa gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa
      901 gcttccaaca aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc
      961 agctgaagtt ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact
     1021 gtatcgatcg agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag
     1081 tattcgtcac ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct
     1141 aaaggatcaa tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg
     1201 ctatgaccgg tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac
     1261 tgtacatgat catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct
     1321 tcgccgtcta ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct
     1381 tccatgatag agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg
     1441 ttttctttta atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct
     1501 agtaatgttc catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact
     1561 ccttttttat tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg
     1621 aagaattcct gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt
     1681 taggagggaa agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct
     1741 ttttcggatt ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc
     1801 cgcaaaaaca gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct
     1861 tatgggctta ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta
     1921 ttttctgatt gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga
     1981 aaagaaatta cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga
     2041 ttgaagataa tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg
     2101 aagcaacttt caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac
     2161 attgggatat gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa
     2221 gagagatccg caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg
     2281 aaagcgatca ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca
     2341 gtcctctgac gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag
     2401 caagagaaga agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga
     2461 tgaatacgaa aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta
     2521 aagagttcga tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc
     2581 agttgcttga attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc
     2641 atatcaagaa attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt
     2701 ggggagtcgg ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca
     2761 actcttagct ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac
     2821 acaactgaca aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga
     2881 atcagttgaa aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca
     2941 ggcgtttcaa aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt
     3001 tatatttatc gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt
     3061 taccttaaca gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc
     3121 gaataaaaat attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt
     3181 gaatcatgaa ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag
     3241 cgttcgtcca attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt
     3301 tattgccagc tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc
     3361 gacgaaagaa gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga
     3421 atttgatgag ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc
     3481 agaaattgaa gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat
     3541 gagaacacct cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc
     3601 tgaaaatcag cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg
     3661 tttggtgaat gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat
     3721 taaaaaattc aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc
     3781 agaagcagca ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga
     3841 ttatgaccga tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga
     3901 aaacggccaa atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga
     3961 agatacggga attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa
     4021 agtagatcct tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt
     4081 gcagcaactt gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg
     4141 aacaaaattc gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg
     4201 tataaaagat catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt
     4261 tagcccgcgg gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta
     4321 aagagtaaga taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct
     4381 tggatctcca atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg
     4441 gaaagcaagg catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc
     4501 gcacaattaa gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt
     4561 ttgatttctt tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac
     4621 atcggccaat ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt
     4681 ttcaagtgct ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt
     4741 tcagcatgaa tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg
     4801 gataaaaaaa gtgaaaggga atagactaag aatgagacag catccactga gcccaataag
     4861 agtttgggca aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt
     4921 aaaaaaagtc tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg
     4981 gatatctggc agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc
     5041 ataaactgac tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg
     5101 aaagaacagc tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg
     5161 ccaattgatc aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag
     5221 gaaggcaaat agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc
     5281 taaagccgga agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac
     5341 ttgattggct aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc
     5401 agaaaagctt gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc
     5461 agtagcatag cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata
     5521 tgaataaagt atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta
     5581 aaaagcaaga ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa
     5641 cactgtttat tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DACCVH010000125         5371 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.130, whole genome shotgun sequence.
ACCESSION   DACCVH010000125 DACCVH010000000
VERSION     DACCVH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.130"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(1273..1938)
                     /locus_tag="IVV98_002711"
     CDS             complement(1273..1938)
                     /locus_tag="IVV98_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7808295.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2064..4100
                     /locus_tag="IVV98_002712"
     CDS             2064..4100
                     /locus_tag="IVV98_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP7808296.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="IVV98_002713"
     CDS             4104..4742
                     /locus_tag="IVV98_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7808297.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="IVV98_002714"
     CDS             4770..5198
                     /locus_tag="IVV98_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808298.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
BASE COUNT         1783 a          815 c          974 g         1799 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag c
//
LOCUS       DACCVH010000126         5311 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.131, whole genome shotgun sequence.
ACCESSION   DACCVH010000126 DACCVH010000000
VERSION     DACCVH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.131"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVV98_002715"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVV98_002715"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP7808299.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="IVV98_002716"
     CDS             complement(1297..2133)
                     /locus_tag="IVV98_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7808300.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="IVV98_002717"
     CDS             complement(2317..3534)
                     /locus_tag="IVV98_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7808301.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="IVV98_002718"
     tRNA            3917..4000
                     /locus_tag="IVV98_002718"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5237)
                     /locus_tag="IVV98_002719"
                     /pseudo
     CDS             complement(4240..5237)
                     /locus_tag="IVV98_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DACCVH010000127         5025 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.132, whole genome shotgun sequence.
ACCESSION   DACCVH010000127 DACCVH010000000
VERSION     DACCVH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.132"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            283..522
                     /locus_tag="IVV98_002720"
     CDS             283..522
                     /locus_tag="IVV98_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808302.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="IVV98_002721"
     CDS             complement(884..1144)
                     /locus_tag="IVV98_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808303.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="IVV98_002722"
     CDS             complement(1329..1826)
                     /locus_tag="IVV98_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP7808304.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="IVV98_002723"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="IVV98_002723"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP7808305.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="IVV98_002724"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="IVV98_002724"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP7808306.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..>5025)
                     /locus_tag="IVV98_002725"
     CDS             complement(4548..>5025)
                     /locus_tag="IVV98_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7808307.1"
                     /translation="CIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIV
                     SVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAF
                     YYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaa
//
LOCUS       DACCVH010000128         5024 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.133, whole genome shotgun sequence.
ACCESSION   DACCVH010000128 DACCVH010000000
VERSION     DACCVH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.133"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..182)
                     /locus_tag="IVV98_002726"
     CDS             complement(<1..182)
                     /locus_tag="IVV98_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7808308.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="IVV98_002727"
     CDS             517..951
                     /locus_tag="IVV98_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7808309.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="IVV98_002728"
     CDS             974..1294
                     /locus_tag="IVV98_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808310.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="IVV98_002729"
     CDS             1435..1626
                     /locus_tag="IVV98_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808311.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="IVV98_002730"
     CDS             complement(1697..1954)
                     /locus_tag="IVV98_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP7808312.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="IVV98_002731"
     CDS             2112..2375
                     /locus_tag="IVV98_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808313.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="IVV98_002732"
     CDS             2399..2587
                     /locus_tag="IVV98_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808314.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="IVV98_002733"
     CDS             complement(2670..2855)
                     /locus_tag="IVV98_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808315.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="IVV98_002734"
     CDS             3070..3441
                     /locus_tag="IVV98_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7808316.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="IVV98_002735"
     tRNA            complement(3591..3663)
                     /locus_tag="IVV98_002735"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="IVV98_002736"
     CDS             complement(3709..4137)
                     /locus_tag="IVV98_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808317.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="IVV98_002737"
     CDS             complement(4197..4955)
                     /locus_tag="IVV98_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAP7808318.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1750 a          784 c          983 g         1507 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tatt
//
LOCUS       DACCVH010000129         4934 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.134, whole genome shotgun sequence.
ACCESSION   DACCVH010000129 DACCVH010000000
VERSION     DACCVH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.134"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            49..861
                     /locus_tag="IVV98_002738"
     CDS             49..861
                     /locus_tag="IVV98_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP7808319.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            858..1658
                     /locus_tag="IVV98_002739"
     CDS             858..1658
                     /locus_tag="IVV98_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP7808320.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1819..3087
                     /gene="rseP"
                     /locus_tag="IVV98_002740"
     CDS             1819..3087
                     /gene="rseP"
                     /locus_tag="IVV98_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP7808321.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3155..4864
                     /locus_tag="IVV98_002741"
     CDS             3155..4864
                     /locus_tag="IVV98_002741"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP7808322.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
BASE COUNT         1605 a          816 c         1102 g         1411 t
ORIGIN      
        1 tataatactt aagatagtgg gaatctttta agtataggag gaaaaagaat gttacgtttt
       61 tttccgcaaa aaaacaaata tattcaagaa aaaagcgaat ttcaatttaa taccgatgga
      121 ccaattcctc agcacattgc catcatcatg gacggcaatg gtcgttgggc gcaaaaccgt
      181 cgtttgccac gagttgctgg ccataaagaa ggcatggaaa cagtaaagaa agtcacaaaa
      241 aaagcatcaa ggcttggagt gaaagtgttg acgctttatg ccttttcgac tgaaaactgg
      301 aagcgaccaa aagatgaagt aagttttctc atgcaactac ctgtcgactt ctttgatacg
      361 ttcgtaccag aattgattaa agaaaatgtc aaagttcatg tcatgggtta tgaaaacgta
      421 ttgccagaac atacgcaaga tgctgtaaga cgtgcaattg agcaaacaaa aaacaatact
      481 ggaatggtat tgaattttgc tttgaattat ggaagcagag cagagatcgt gactgctgtc
      541 caagaaattg ccgaagaagt agcaaaagga gaaatacacg cagaagaaat cgatgatgaa
      601 ttgattgcta agcatttaat gacaggtttc ttgcctaaag agttacaaga tcctgagctg
      661 atgatccgta caagtggaga agagcgaatt agtaattttc tgttatggca gatcgcatat
      721 agtgagctgt attttacaaa agcgctttgg cctgattttg atggtgcgca tcttgaagaa
      781 gcaatcgcct cttatcaaaa tcgagaccgt cgattcggcg gtgtaaaaaa aacagaagat
      841 gagaaagggg atcagtcatg aaacaacgtg tggtcacagc agccgtggcg ctagtcttgt
      901 ttattccgat tatatggatc ggaggcatag cggttgagct tacagcagca atcttagcag
      961 taataggagt ttacgagctg tttcggatga aaggattgac actcttaagt tttgaaggag
     1021 ttttatccgc cgttggtgca gtgttacttg ttttgccaaa agaaagatgg tttttctttc
     1081 ttccagagaa tgtaagtaca tttatgttat tttatcttat agttatgatt cttttaggaa
     1141 catcagttat ttctaaaaat acgtatacga ttgatgaagc aggttttcct gtgcttgtca
     1201 gcttgtatgt gggaataggt ttccagaatt ttgtcaatgc acgaacagaa agcttggctg
     1261 ttttgatatt tggtctattt attgtttggg caactgatat cggagcatat atggttggtc
     1321 gacgttatgg tcagcataag ttaagtcctg atatttcgcc caacaaaacg attgaaggtg
     1381 cgctcggtgg tattggtagt gctgttgtag tcgcatttct ttatttattg ctatacccag
     1441 caaaagaact atttaatcat ggtatgtttg tcatgcttct gatgacgatt attttttcag
     1501 cagtcggaca atttggtgat ttggtcgaat ctgcaatcaa acgtcattat gatgtgaaag
     1561 actcgggaaa tatcttacca ggccatggtg gaatcttaga ccgtttcgac agtttgctgt
     1621 ttgtatttcc tatcatgcat ttatttggca ttatttagta agtatacctg cgtttctttg
     1681 tgaatttcat aaaagacgca ggtttttatt tttcattata ttgatactat tggtgtcttt
     1741 ggtatactat ggtaaaatta tagtgtttta tcgttgtttt ataaaaaaca caaaaaacaa
     1801 gtaaaggaga aaaaagctat gaaaacgatt ctgacattta tcatcgtttt tggtatatta
     1861 gtgattgttc atgagtttgg tcatttcttc tttgcgaaac gatcaggaat cctcgttcgc
     1921 gaatttgcta tcggtatggg tccgaaaatt tatgggcatc aagcaaaaga cgggacaaca
     1981 tatacgcttc gcctattacc tattggcggt tatgttcgaa tggcaggcaa tggggatgat
     2041 gaaacagaaa tggcaccagg aatgcctctt tctcttttac taaattctga cggcatcgta
     2101 gagaagataa atttaagtaa gaaaatccaa ttgacaaatg ctatcccgat ggaattgagc
     2161 cgttatgatt tagaagatga gctgactatc actggttatg tgaatggaga cgaaacagaa
     2221 gtagtaacct accctgttga tcacgatgcg acgattattg aaaacgacgg aacagaaatc
     2281 agaattgcgc caaaagacgt acagttccaa tcggctaaat tgtggcagcg tatgctgacc
     2341 aactttgctg gacccatgaa taactttatt ttggcaatcc tgttattcat cattctggca
     2401 tttatgcaag gtggtgttca agtgacgaac actaatcgcg taggagagat catgcctaat
     2461 ggagctgcgg cagaagcagg cttaaaagaa aatgatgagg tagtcagtgt ggacggaaaa
     2521 gaaatccatt catggaatga tctgacaaca gtcattacga aaaatccgga taaaacatta
     2581 gactttaaga tcgaacgaga aggtcaggtg caatctgtcg acgtgacacc gaaatctgta
     2641 gagtcaaatg gcgaaaaagt tggccaactt ggtataaaag ccccaatgaa tacaggtttt
     2701 atggataaga tcattggagg gacgcgtcaa gctttcagcg gttcattgga aattttcaaa
     2761 gccttaggat cactatttac aggtttcagt ttagataaat taggcggacc tgtcatgatg
     2821 taccaattgt cttcagaagc agcaaatcaa ggtgtaacaa ctgttattag tttgatggcg
     2881 cttctttcaa tgaatctcgg aatcgtcaat ctgcttccga ttcctgcctt agatggcggg
     2941 aaattagtct tgaatatttt tgaagggatt cgcgggaaac cattaagtca agaaaaagaa
     3001 ggaatattga cattagctgg ctttggattt ttaatgttgt tgatggtgct agttacatgg
     3061 aacgatattc aacgattctt tttctagaaa aagttgacaa atagggtata ataacaaacg
     3121 ataactattt tgaggaaata aaggagtata tagaatgaga caatcaaaaa tgttgattcc
     3181 aacattacgc gaagttccaa atgatgcaga agtattaagc catcaaatct tgctaagagc
     3241 tggatatatc cgccaagtat cagcgggtat ttattcatat ctgccattag caaatcgtgt
     3301 attggaaaaa ctgaaacgca ttatgcggga agaatttgaa aaaatcggag cggtagaaat
     3361 gctgatgcct gccatcttgc cagcagaact ttgggaagaa tccgggcgtt acgaaacata
     3421 tggaccaaac ttgtatcgtt tcaaagaccg caatgatcga aaaatgatcc ttggaccaac
     3481 tcacgaagaa acttttactg atttgatgcg taatgaaatc aattcatata agaaattacc
     3541 tttaaatctt tatcaaatcc aacctaaata tcgtgacgaa aaacgacctc gcttcggttt
     3601 gcttcgcgga agagagttta tcatgaaaga tgcgtattct ttccatgcaa cggaagaaag
     3661 tttggacgag acatataaag attacgaaaa agcctacacc gaagtattca agcgttgtgg
     3721 cttagaattt cgctcgatta tcggagacgg tggcgcaatg ggcgggaaag actcaaaaga
     3781 attcatggcg atctcagaaa tcggggagga tacgatctgt tattcgactg aaagtgatta
     3841 tgctgcaaac ttggagatgg ctacaagcta ctatgtatca aaaaaatcgc atgaaacaca
     3901 gcttgaattg gagaaagtag ctacacctaa cgtaaaatca attgacgaag tagcagattt
     3961 cttttctgtt gaacctcaaa aaatcatcaa gtctgtattg ttcattgcgg atgaacaacc
     4021 tgtccttgtt ttggtacgcg gagaccatga agtcaatgac gtaaaactga aaaacttttt
     4081 atctgctgac tttttagaag aagcaacaga agaagaagca caaaaatatc taggtgctga
     4141 gtttggttct gtcggaccag tcggtgtttc agatgacgta aaagtatatg cagaccgtta
     4201 tgtccaagat ttagcgaatg ccattactgg agcgaacgaa acaggattcc actataaaaa
     4261 tgtgaatcca gaacgcgatt tcactgtact ttcttatgaa gatcttcgtt ttgtacaaga
     4321 aggagatcct tcaccagaca acaatggtgt tcttgccttt actcgaggaa tcgaaatcgg
     4381 acatatcttc aaaatcggca ctcgttacag tgaatctatg ggagcaactg tactagacga
     4441 aaatggacga gaaaaatttg tgattatggg ctgttatggt atcggtgtaa gtcgtttatt
     4501 atcagcaatc gtagaacaac attcagatga acaaggaatc aactggccaa aaggaattgc
     4561 gccatttgat ttgcatatcg tccaaatgaa tctaaaagac gaataccaaa caaacctgac
     4621 gaatgaacta gaagaagcga tgacaaaagc tggctatgaa gtactggttg atgacagaaa
     4681 tgaacgcgca ggagtgaaat tcgcggattc tgatttgatt ggctgtccaa tcagaatcac
     4741 tgtcggtaaa aaagcagtgg atggaatcgt agaagtgaaa atcaagaaaa ctggcgaaat
     4801 ggttgaagta cgtaaagaag aattggtgaa tactttacca atcctcttga accaaggcga
     4861 ataataagcg ttaaaacaca gaaaataaaa atagctgaat cagctgtttt tgacaatctg
     4921 atgattcgct ttta
//
LOCUS       DACCVH010000130         4931 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.135, whole genome shotgun sequence.
ACCESSION   DACCVH010000130 DACCVH010000000
VERSION     DACCVH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.135"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            83..970
                     /locus_tag="IVV98_002742"
     CDS             83..970
                     /locus_tag="IVV98_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7808323.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="IVV98_002743"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="IVV98_002743"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP7808324.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="IVV98_002744"
     CDS             2272..2718
                     /locus_tag="IVV98_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7808325.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="IVV98_002745"
     CDS             2991..4343
                     /locus_tag="IVV98_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP7808326.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="IVV98_002746"
     CDS             4514..4801
                     /locus_tag="IVV98_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808327.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1395 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt t
//
LOCUS       DACCVH010000131         4900 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.136, whole genome shotgun sequence.
ACCESSION   DACCVH010000131 DACCVH010000000
VERSION     DACCVH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.136"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            175..975
                     /locus_tag="IVV98_002747"
     CDS             175..975
                     /locus_tag="IVV98_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7808328.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            994..2862
                     /locus_tag="IVV98_002748"
     CDS             994..2862
                     /locus_tag="IVV98_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7808329.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            2855..3346
                     /locus_tag="IVV98_002749"
     CDS             2855..3346
                     /locus_tag="IVV98_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAP7808330.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3334..3888
                     /gene="srlA"
                     /locus_tag="IVV98_002750"
     CDS             3334..3888
                     /gene="srlA"
                     /locus_tag="IVV98_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP7808331.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            3906..>4900
                     /locus_tag="IVV98_002751"
     CDS             3906..>4900
                     /locus_tag="IVV98_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP7808332.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1704 a          767 c         1031 g         1398 t
ORIGIN      
        1 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
       61 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
      121 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
      181 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
      241 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
      301 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
      361 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
      421 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
      481 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
      541 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
      601 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
      661 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
      721 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
      781 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
      841 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
      901 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
      961 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     1021 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     1081 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     1141 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     1201 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     1261 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     1321 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     1381 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     1441 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     1501 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     1561 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     1621 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     1681 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     1741 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     1801 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     1861 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     1921 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     1981 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     2041 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     2101 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     2161 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     2221 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     2281 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     2341 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     2401 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     2461 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     2521 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     2581 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     2641 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     2701 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     2761 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     2821 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     2881 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     2941 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     3001 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     3061 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     3121 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     3181 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     3241 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     3301 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     3361 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     3421 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     3481 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     3541 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     3601 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     3661 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     3721 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     3781 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     3841 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     3901 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     3961 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     4021 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     4081 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     4141 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     4201 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     4261 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     4321 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     4381 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     4441 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     4501 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     4561 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     4621 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     4681 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     4741 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     4801 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     4861 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DACCVH010000132         4808 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.138, whole genome shotgun sequence.
ACCESSION   DACCVH010000132 DACCVH010000000
VERSION     DACCVH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.138"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(207..1169)
                     /locus_tag="IVV98_002752"
     CDS             complement(207..1169)
                     /locus_tag="IVV98_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7808333.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="IVV98_002753"
     CDS             complement(1171..2610)
                     /locus_tag="IVV98_002753"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAP7808334.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="IVV98_002754"
     CDS             2795..4741
                     /locus_tag="IVV98_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAP7808335.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1534 a          822 c          791 g         1661 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatt
//
LOCUS       DACCVH010000133         4808 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.139, whole genome shotgun sequence.
ACCESSION   DACCVH010000133 DACCVH010000000
VERSION     DACCVH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.139"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="IVV98_002755"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="IVV98_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP7808336.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="IVV98_002756"
     CDS             complement(2066..3064)
                     /locus_tag="IVV98_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP7808337.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="IVV98_002757"
     CDS             complement(3290..3943)
                     /locus_tag="IVV98_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP7808338.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="IVV98_002758"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="IVV98_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP7808339.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1415 a         1007 c          745 g         1641 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaa
//
LOCUS       DACCVH010000134         4740 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.140, whole genome shotgun sequence.
ACCESSION   DACCVH010000134 DACCVH010000000
VERSION     DACCVH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.140"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            153..959
                     /locus_tag="IVV98_002759"
     CDS             153..959
                     /locus_tag="IVV98_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HAP7808340.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            977..1804
                     /gene="vanW"
                     /locus_tag="IVV98_002760"
     CDS             977..1804
                     /gene="vanW"
                     /locus_tag="IVV98_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAP7808341.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            1801..2772
                     /locus_tag="IVV98_002761"
     CDS             1801..2772
                     /locus_tag="IVV98_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP7808342.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2765..3793
                     /gene="vanB"
                     /locus_tag="IVV98_002762"
     CDS             2765..3793
                     /gene="vanB"
                     /locus_tag="IVV98_002762"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP7808343.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3799..4407
                     /locus_tag="IVV98_002763"
     CDS             3799..4407
                     /locus_tag="IVV98_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP7808344.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         1332 a         1002 c         1262 g         1144 t
ORIGIN      
        1 attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga aaactacaga
       61 ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca gccacaaatc
      121 gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat cattccaatg
      181 cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt ctatgtgcgt
      241 tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct tccgtattgg
      301 aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact gacgtagtgg
      361 agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa caggaatgga
      421 gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg gagcttgagc
      481 aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa gatttgtttg
      541 atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga acaacagaaa
      601 aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc tacacctctg
      661 cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc gagcatcagc
      721 ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac gaggtttata
      781 gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca ccagacaaga
      841 cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc atcgaagctg
      901 ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca gaaaaatgag
      961 aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
     1021 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
     1081 ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa cggattgcgc
     1141 attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg tgttcaactt
     1201 aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa ccttttcttt
     1261 ctggtggctg gtacgccatg cggacaaaga taccccctat aaagacggcc ttacggtgac
     1321 caatggtaaa ctcaccacca tgtcgggcgg cggtatgtgc cagatgagca atttactatt
     1381 ttggatgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg aagtaaagga
     1441 gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt cagagggctg
     1501 gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg tgaccttaga
     1561 tgatgagaaa atcatcggtc aggtgttcgc cgacaaagag ccccaagcat tatacaaaat
     1621 tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat atgcccaggt
     1681 taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc tgctttatac
     1741 aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg aggagaacca
     1801 atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc aaatgctttc
     1861 cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc gatatcggca
     1921 gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taagccataa gtccgaggtt
     1981 tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc tacccgcagc
     2041 atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc ggttggcacg
     2101 gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct gatggccata
     2161 cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt ggatcgtatc
     2221 cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca tatcgggcaa
     2281 gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga taacagccga
     2341 aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga tattgttacg
     2401 ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca aattggagag
     2461 atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga taccggggcg
     2521 ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt gttggagggc
     2581 gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc ctttttgtcg
     2641 cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta cactgagcgt
     2701 gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga aaggagttta
     2761 cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg aacatgatgt
     2821 gtcggtaaaa gccgcaatag aaattgctgc gaacattgat acggaaaaat tcgatccgca
     2881 ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat gtacggaatg
     2941 ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg ggctgcttgt
     3001 catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg ttttgcatgg
     3061 caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta tcccctatgt
     3121 gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct acattcttac
     3181 aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg acaagccgga
     3241 ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt cgtcctttgg
     3301 cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg caggacaata
     3361 tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt gtgcggtcat
     3421 ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga gccacggtat
     3481 cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga tgattacagt
     3541 tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa agaaagtata
     3601 tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg aggatggcgg
     3661 catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc gctacccacg
     3721 tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga ttacattggc
     3781 gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat gttgcatggc
     3841 gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc ggtggatggg
     3901 tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg cgaggcacaa
     3961 atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg gccaagaact
     4021 gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac aaaagaaaaa
     4081 ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc ctcacaatcc
     4141 agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac aggggaactt
     4201 gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac agcaaaaggg
     4261 ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga aagcagcgga
     4321 tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc ataccccgat
     4381 acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag attttggatt
     4441 tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa agcatctttt
     4501 gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa aaaaaccgct
     4561 gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt tgagaaatca
     4621 aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga tgccgctatg
     4681 ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc cttgcccctc
//
LOCUS       DACCVH010000135         4714 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.141, whole genome shotgun sequence.
ACCESSION   DACCVH010000135 DACCVH010000000
VERSION     DACCVH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.141"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(213..443)
                     /locus_tag="IVV98_002764"
     CDS             complement(213..443)
                     /locus_tag="IVV98_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAP7808345.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(673..1491)
                     /locus_tag="IVV98_002765"
     CDS             complement(673..1491)
                     /locus_tag="IVV98_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7808346.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1652..2341
                     /locus_tag="IVV98_002766"
     CDS             1652..2341
                     /locus_tag="IVV98_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP7808347.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2355..3857
                     /locus_tag="IVV98_002767"
     CDS             2355..3857
                     /locus_tag="IVV98_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7808348.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3870..4346
                     /locus_tag="IVV98_002768"
     CDS             3870..4346
                     /locus_tag="IVV98_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP7808349.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(4443..4553)
                     /locus_tag="IVV98_002769"
                     /pseudo
     CDS             complement(4443..4553)
                     /locus_tag="IVV98_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1590 a          673 c          830 g         1621 t
ORIGIN      
        1 tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat gaactaataa
       61 ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc ataaactttt
      121 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca taacattgaa
      181 gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      241 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      301 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      361 tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      421 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      481 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      541 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      601 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      661 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      721 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
      781 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
      841 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
      901 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
      961 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
     1021 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1081 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1141 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1201 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1261 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1321 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1381 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1441 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1501 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1561 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttgttatcca
     1621 aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt tagatcttat
     1681 ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt acaaagagga
     1741 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     1801 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     1861 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     1921 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     1981 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     2041 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2101 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2161 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2221 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2281 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2341 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2401 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2461 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2521 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2581 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatc
     2641 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     2701 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     2761 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     2821 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     2881 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     2941 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     3001 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3061 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3121 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga ttaccagcag
     3181 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3241 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3301 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3361 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3421 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3481 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3541 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3601 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3661 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     3721 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     3781 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     3841 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     3901 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     3961 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     4021 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4081 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4141 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4201 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     4261 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4321 attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa aataagctaa
     4381 ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt ctgttcattt
     4441 ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt aaagttataa
     4501 aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt caaatataaa
     4561 atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg tttactcaac
     4621 ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga accttagcac
     4681 tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DACCVH010000136         4646 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.142, whole genome shotgun sequence.
ACCESSION   DACCVH010000136 DACCVH010000000
VERSION     DACCVH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.142"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(100..399)
                     /locus_tag="IVV98_002770"
     CDS             complement(100..399)
                     /locus_tag="IVV98_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7808350.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            750..1382
                     /locus_tag="IVV98_002771"
     CDS             750..1382
                     /locus_tag="IVV98_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP7808351.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1505..2143
                     /locus_tag="IVV98_002772"
     CDS             1505..2143
                     /locus_tag="IVV98_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7808352.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(2262..2334)
                     /locus_tag="IVV98_002773"
     tRNA            complement(2262..2334)
                     /locus_tag="IVV98_002773"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2299..2301),aa:Thr,seq:cgt)
     gene            2455..2697
                     /locus_tag="IVV98_002774"
     CDS             2455..2697
                     /locus_tag="IVV98_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808353.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(2836..3465)
                     /gene="upp"
                     /locus_tag="IVV98_002775"
     CDS             complement(2836..3465)
                     /gene="upp"
                     /locus_tag="IVV98_002775"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP7808354.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3599..4546)
                     /locus_tag="IVV98_002776"
     CDS             complement(3599..4546)
                     /locus_tag="IVV98_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7808355.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
BASE COUNT         1439 a          867 c          755 g         1585 t
ORIGIN      
        1 ttagaataaa aaaatacaga ctctgttcaa ataaatgaac ctagcctgca ttatgagatt
       61 gactatactt tttaattcat tgagatgaat aactcgtttt tataaatgcc caaaagtaat
      121 cggtgccgaa gccattcctc gacctaattc tttttcaaat tttcctattg ttgatatctc
      181 catataaaac ggtgatactg gtttagacaa ttctcccctg attgctaacg gacgtaaact
      241 acgttccaaa ttatttatga ctttaggata atactgacct ttttctaagc ctgtctttgc
      301 gtctatcaaa agtatacgtt ccttttcttt gatctctgga tttaaaacga gatcatataa
      361 ttttagtacc atgttttcta tttcttcact tttagacatc acgatttcct cccaaaaata
      421 tatttcttcc cactacattc tataaacaaa gtatacgcta catctagatt tttttaaatc
      481 attactggat tgttaaaacc tttcaataca ctgttatggc aacgattttt attttaaaaa
      541 cattctaaat taaatcagta aaaattttta ttctaagatt tttattagaa ttacgcctaa
      601 tttgtgtctc tcagggcaat tctaagaacg tttcaagaga tagcgacact atcgttatcg
      661 aaaaaggcga aaacctatct cattttctgc taatgtaagt tggtttagct tttgttaata
      721 tgactttatg aaaatggagg taattaaata tgatttttcc taaagttaat gaagcaagct
      781 tgaataaagg atcctttttt catatctatg aaaacgaaga ttttgaactg tataatatcc
      841 tttcacaaaa agaggtcatc gaaaaccaaa taatctgcca tccaattatt tacaaatcta
      901 ttttcaagta tgcatttttt gcttccaatg attttcaaag aatggagatt accgactgta
      961 tattcgaaaa ctgtgatttt tcaggctgta tattgacaaa aagcatgttg catcgcgtga
     1021 aatttgtcaa ttgtaaatta acaggtacta aattgatgga aagttatatt gggaacacgt
     1081 tattcgagaa ttgtaaaatg gactatgtaa atttatctgg ttcaaacata aaagaaagta
     1141 cctttgagca ctctgtctta tcaagcgcag attttgtaga ctgttccctc actaaaataa
     1201 tgttttctac taatgattta gaaaatgcta gcttttttga tactgattta aaaaatatcg
     1261 atttaagtag caactccttt gaaatgattg aagtacgctc ggaacatcta aaaaattgta
     1321 cgcttaatca gttgcaagca cttggttttg ctagaaaatt tttacaaata aaagtagtat
     1381 aatcaaaatg aatatataag ataaattttt agcaatacaa atatccataa aaaaacattg
     1441 cctattttaa ctcttcatgt atactgactc tatcttcaaa aactgaatag taggagttat
     1501 tatcatgaat aacattttag gaaaaaaaat agaacttaaa aaagggatat tgggcactat
     1561 tgtcgttgta ctcggtttgt tagggttgct atttgcgcca tccattatta gcattttttc
     1621 tttaactatc actggattta tagcatttac acttgttttt ggtaaaaaag atacgaaaaa
     1681 aatgttctcg aaacctgtcg ctcctgtcaa aaatatagcc aaatattttt ttatcaatgt
     1741 agtaatcagt gccgcagtct cggtattttt gcaacaaatt ttgaaatggg gtttaacagg
     1801 caatccaata aatgaggctt tcagcccgtt attatttatt attttgccta tcatgatact
     1861 tggagaagaa ttgttctcag tgtattttct cgctattttt tctagtaagt tcagcattcc
     1921 tgtcgctagt ttcttgtcag caatcatctt tggatttatc cattacagta cttatgataa
     1981 tggaaatatt ttacacactg tagcacacat ccttttgata caaggggtgg caagattgtt
     2041 attcaaccaa gctgccatta aaagcaactc gatcattaca agttgggcag ttcatgtgat
     2101 atttgatttc acagctatat tgctagtcgt tttattctcc taaattttta tagaaataat
     2161 acatgctcta ttgctaagaa agcatacttt atttccttta aacaaaaaga cagatgtatc
     2221 aatggattaa aaatccttga tatatctgtc ttctctttta atgccagcta tagggatcga
     2281 acctacgacc tacgcgttac gagtgcgttg ctctaccaac tgagctaagc tggccttatc
     2341 caaaagaaat tatatactct atttggctga ttgtaaagag tccgatggaa aattagttta
     2401 atttcatgat atttttcata aaacgtggta taattgatgt gaaaggcagg ttttatgaaa
     2461 atggcaactt ttggaaaatt tgatacaact atcgtaccat cggaaattgg tgaaaaattc
     2521 aagatcaata ctcacgtaat gttcacaatt cacggcaagt cgcaaactgg aacgatttca
     2581 aagcaattga aaaattccgc tgttgttgag attgatgaaa ctgcagaaaa tgcgaacttg
     2641 atgacgcaaa gtaagggtgt agtaatcgtt aactacaaag aactaaaaaa gatttgaatt
     2701 tgaccatctc tgcatttttg ggatggtttt tttatatgca aacgaaagct gtgaaaaagc
     2761 tgttctgcat caaacgttaa aaatgaccaa aaaaggatgt gacaaaagtt gtgtcacacc
     2821 ctttttcgta tttacttatt ttgtaccaaa caaacggtca cccgcatccc ctagtccagg
     2881 aacgatataa ccatgttcat tcaatttttc atctagagaa gctgtataga tgtcaatatc
     2941 aggatgcgct tcttgcaaag cttttactcc ctcaggtgct gctaccaaac aaacaaattt
     3001 aatgttcgac gcgccacgtt ctttcaatgc atcgattgcc atgattgctg atccgcctgt
     3061 tgccaacatt ggatctacta caaacaactg acgtgcatca atgtcttctg gaagtttgac
     3121 gaaatattca tgtggttcca atgtttcttc atctcgataa agaccgatat gtcccacttt
     3181 agcagctgga atcaattcca agataccgtc aaccattcca atacctgcgc gcaagattgg
     3241 aataatcgct acttttttac cagacaacgt tttttgtgtt gtttcagtga tcggtgtttc
     3301 gatcacgatg tcttccaatg gcatatcccg tgatacttca tatgccatca acatagcgat
     3361 ttcatcgact acttcacgaa aaacctttgt tccgcagttt ttgtcccgaa taatagttag
     3421 tttgtgttga atcaatggat gatcgatcac ttgaaatttg cccatttttt aagctctcct
     3481 ttgttctgtc gtttcttttt aattgtaaaa caaaatcaag tgattgacta gtcaaactcg
     3541 ccatttttcc taagaaaatc cgtttttgaa aagaagtttt cctgcggaca agcaaagctt
     3601 attctttttt cttgatccaa gaagtagata atgccattgc tgcacgcgtt gcctttgtct
     3661 gatccatagc atttaccatg acaaaatcat ggatgattcc ttggaagcgt acttgtgtaa
     3721 caggaacccc tgcatcacga agtttgcgcg cataagcctc accttcatct cttaatacat
     3781 ccgcttctcc cgttaaaatc attgctgaag gaagatcatt tagttcattt atatttgctc
     3841 tcaaaggcga agctgtgatt tcagcacgct cttcttcatt cgtcgtatat tggtcccaaa
     3901 accacatcat tccttctctt gtcaaaaaat agttttctcc gaattcatga taggaatctg
     3961 tatcaaaatc agcgtttgtg actggataat acagcaattg cttggatatt gggaggccct
     4021 ttcgttcttt tgttaagatc gtcatgactg tagccatgtt accacctact gaatctcctg
     4081 caacgattag attctcgaga tccagatttt ttgacttggc taatttattc agctgttgca
     4141 acacagcata attttgttca attgctgttg gatattttgc ttctggtgat cgactatatt
     4201 ctggaaagac aacgacggaa ttcgtacgaa ccgcaagttc tctgatcaat ttatcatggg
     4261 tttgagcact gccaaaaacc cagcctgctc catgaatata aaaaataact ggtaatttat
     4321 ccatattccc ttctggtcgt acgagacgaa tattgagttt tccccattcg ccagtatcca
     4381 ccatcaagtc ttcaatatcg acggaatatt tgttcacagg tgattcttgt acttcttcta
     4441 gtaaaactct tccttcttcc ggtgctagtt catagatacg cggatgaggc gcatttgcat
     4501 cactgaatgc tactgcttcc ttttctaacg agatacgatc agtcatgact tttcctccct
     4561 gagatttagt gtgaagacta aaattacacc tcatatacta gagagcatca ccgatattgt
     4621 caaagaatcc gttttcccaa aaataa
//
LOCUS       DACCVH010000137         4592 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.143, whole genome shotgun sequence.
ACCESSION   DACCVH010000137 DACCVH010000000
VERSION     DACCVH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.143"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            188..2857
                     /locus_tag="IVV98_002777"
     CDS             188..2857
                     /locus_tag="IVV98_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP7808356.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2948..3568)
                     /locus_tag="IVV98_002778"
     CDS             complement(2948..3568)
                     /locus_tag="IVV98_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7808357.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3682..4221
                     /locus_tag="IVV98_002779"
     CDS             3682..4221
                     /locus_tag="IVV98_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808358.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4218..4556
                     /locus_tag="IVV98_002780"
     CDS             4218..4556
                     /locus_tag="IVV98_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAP7808359.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1422 a          790 c          860 g         1520 t
ORIGIN      
        1 aaatttttaa gggtgggact tttgattcct accctttttt tgcgtttatt tttgttatac
       61 gaacaaatta tgaagttatt tattctaaat tttatttttt tgtgaaaatt agactctttt
      121 taagcagaga aaaacaagga tatgataaac tgaatacaac ttcatagaaa tttggtggaa
      181 aataaatatg aaaaaaaatt taaagtcatt ctttagagaa aacggacgct acgcagcagc
      241 tagtttcctg attccgtttt tgattttagc acttgtttat ctaagtatcg ggatctatcc
      301 tggaagcagc agaagtattt tggcaagtga tgccttttca cagttttcta attttcatgc
      361 cagcttccga aatgttcttc ttggaaagca aagtattttt tatacatgga atgcttctct
      421 aggattgaat tatttatctt taatttctta ctatctaggc gggatcttca cgccactggt
      481 gttctttttt ccaaaccaga tgatgccaga tgcactgtat gttctgactt tgcttaaggt
      541 cggctgtgcc ggattggctt tttggtttct tgcacgtacg ttcaagattc ctcgctgggg
      601 gcatgttgca cttagcgtca gttacgcatt gatctcattt atcactgcac attcggagat
      661 catcatgtgg ctggatgcat ttgtttatct tccattagtg attttgggga ttcatcgtgt
      721 tatggatctt aaacggccga aacttttatt tatcagttat ttactcttgt ttttatccag
      781 tttttatatg ggttttatga ttggcgtatt ttctttctta tattttatcg cccgtctatt
      841 gacaaactgg tcagaatata aaaaaacgat tgttccttat ggtatcactt ctttactggc
      901 aggcggcgct tcaatgatca ttgtattgcc agcagtgctg gatcttcggt caaatggcga
      961 ggcactgagt cagatcacta cgttgaaaac agaagcgact tcttatctgg atctaatcat
     1021 gaaaaatatg attggtgttt atgacacgac aaaatacgga tcgattccgt tcgtttacgc
     1081 aggtctgcta ccattagtcc tctgtctgtt ttattttgcc agtcggaaag taccgttgaa
     1141 aaataaattt ttgtacggca gtcttttcgc catacttatc gcaagtttct atcttgttcc
     1201 attgaatttg ttctggcatg gtatgcatgc accgaatatg tttttattcc gttatgccta
     1261 tctgttctct ttcttagtgc tcctgcttgc aggaaaagga tgggaaaaga tagaacaaga
     1321 cgatcgtggg ctgttgttag gaatcatttt ggtcgtagct gctctctttg cggtggcatg
     1381 gggcatcaaa cctgaaggaa gctacaccta tgtgacgatg acttcctttg tattgacagt
     1441 ggttttctta gggatttatg cttttgctgt gggattttat cagcataaaa aactttcatt
     1501 caatcatctg agtatattgt tattattgat catgtctgct gaagcactgg tcaatacgaa
     1561 cagtatgatc catggcattc ttgatgattg gaattatgct tcccgcagtt tatatactga
     1621 tccttatcct gacttgaaag ctcttgtaaa tgaaacaaaa aaagattccg actcgtttta
     1681 ccgcttggaa aatctggatc cagtatctgc aaacgattcg atcaactatg gttacagtgg
     1741 tatcagtttg ttttcttcta taagaaatcg taattcttcc tcttacctgg ataaattagg
     1801 tttccgttca agagggacaa atttgaatat ccgttataac aataatactt tgctaatgga
     1861 tgggtttaca ggaatcaaat ataacatttc taaaaacgaa agcacgttca gtaaatatgg
     1921 cttccgccaa gctggtcaaa gtggcgacta tacactgtat cagaatgtca atgcattgcc
     1981 actagcattt actgcaccgt tgtccgttaa tgatgttgag cagccagtga cagataattt
     2041 gaccagtcag acaaacttga tcaatacatt gtctggttta aatgaacagt attttacatt
     2101 ctatacacct actttgaaga atcagttgaa tacgacgatc acaaagacaa cgactggcgt
     2161 cacttactca gaaacagcag ataaccagcc aaaagagctc acttgggaag tccatgtgcc
     2221 tgcaaataca caagcttact taagtttgtt cccaaccaat tttgcacaat tagaaagttc
     2281 tagtgcgacg atcactgtca atggtacatc gcgaaaaacg caaatcaaca tttctggtca
     2341 atactatgat cttggctatt atcctcaaga gacaacagtg acatttactg caagttttta
     2401 tggaacgaaa gaagtaagtt tcatggagcc taaagtcgtt ggtctagatg ttgtagccta
     2461 tcaagccgca atgaatcaga tcaaagaaaa aggtgtcgaa atggaagcca ctggcagaaa
     2521 agcttctggg actgtaaata ccgctgaaga ttccatgttg gtgacaacta ttccttatga
     2581 caaaggatgg aaagctaaaa ttgatgggaa accagtcaag gtcagcaatt tcaaagacgc
     2641 attcttgatg ataaaagttc cagcaggtaa acatactgtc actttcagtt acttgcctga
     2701 aggatttacg ataggtgcaa tcctttttgt cctatgtatt gcattgttta ttctttatgt
     2761 ctggtacctt gaccgcaatc gcccctttta tggcacgatt gatccagcaa tagaagaaaa
     2821 accgcgaaat acacacagaa gaagacgaag aaaataaaga aacgatggaa tctgtgtcac
     2881 tcttctattt aaatggcaaa aatttcaatc tttaaatgac aaaaaccacc tgatttttgg
     2941 tggtttttta tatacctatg actaaactat ctcttgctgc ttcgacaact tctacagtga
     3001 tcttatccat ttgattgatt cttaaaatcc gatcaatctg cgcaaataaa cgatgaataa
     3061 gcctaaaatt tccttttgtg atcttaatga tagttgtgat agcctcataa tcagaaaaat
     3121 cttctagctt gatatcaatt cctaaatctg cccatttgta ttccaaaata tgatgtgttt
     3181 cgtccttact aaggttatca aattcatgtg caaatcctat gcgagagtaa agctgcggat
     3241 aacgagacaa tcttttttca ataccaggca taccgataag aaccattgcc agatcatttc
     3301 tatcgtaaat atctcttagc tgttctaaat gctgaagctt taaacgatca atttcatcga
     3361 caataattaa gtcaattgct tcataggttt taggcacagg aggatcttct tgattgtatt
     3421 ttagtaccat atgcattgct ttagtcagac ctattctact agttattgtg ttaatatccg
     3481 aactgacacg agacatcttt tcagctggta cagtataaaa aactttattt acacttaata
     3541 tttcatctgt tgcatttatc aagaacaaga aaaagtctga atattcaaaa aaaataacgg
     3601 tgtacatttt taaaaggaga tgtataatcg agatttagaa agcgttttcc tcaaaattta
     3661 atgaattagg aagtgattac tatgaaaaaa ttatttagcg cactttttat tctgttattt
     3721 ggctttattg gtattgggac ttctggaaat atagttaaag ctagcacgat ggttgaacaa
     3781 acaagtgaaa tggcaaaaac ttttagtcaa ttaacaccag aagaacaaag ttacttcaaa
     3841 tccaaaggat ttagtgataa agatactttt tacactcaaa agatagagcc tcaagatccg
     3901 aaaacacgtt tttctgcaaa tgtattgcgg ttaaccgcat ctactaaaaa aattactaat
     3961 acgcaggggc ggacagaata tattataaca agtcccaatt cggcgatgta tcgtatttct
     4021 acacgcttga gtttaggtag tgcaaaatca tatactcaaa cagtaaatct agctaattct
     4081 tatggttatg gtggaggaat gtattttaca tttactggga aaagacaata ttacagtgta
     4141 aaattagcta tgcaagttta taatacattt ggtgtagggt cagtctcttg cactgcggga
     4201 ggattgacaa taggaaaatg ataatttctt actatgtctt aaatagaagt gatgatgaag
     4261 gactcttcgt ttttcaatca ttacatgagg atacgatgct aaaagagttt tataatcgga
     4321 ttaagaataa acagatagaa acaaatttat attttttaag tgactctatc ttgcctttta
     4381 ttagcaaccc taaaattctt aacttgttgc agacaaaaga tttgaaaagt ttaccgatta
     4441 ttgtcattga tgaggaaatt gtaaaatatg gcgcttatct aagcgtagaa gaattagaaa
     4501 aattaactaa cattggaatg agtattcagg aggataatgg ggtacatgga acatagaatg
     4561 aatatgcaca gttgagaacg gaatttgaca tt
//
LOCUS       DACCVH010000138         4565 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.144, whole genome shotgun sequence.
ACCESSION   DACCVH010000138 DACCVH010000000
VERSION     DACCVH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.144"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(1014..1304)
                     /locus_tag="IVV98_002781"
     CDS             complement(1014..1304)
                     /locus_tag="IVV98_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808360.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1646..1942
                     /locus_tag="IVV98_002782"
     CDS             1646..1942
                     /locus_tag="IVV98_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808361.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="IVV98_002783"
     CDS             1949..3901
                     /locus_tag="IVV98_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP7808362.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="IVV98_002784"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="IVV98_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP7808363.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1562 a          803 c          755 g         1445 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaa
//
LOCUS       DACCVH010000139         4431 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.145, whole genome shotgun sequence.
ACCESSION   DACCVH010000139 DACCVH010000000
VERSION     DACCVH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.145"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(543..2048)
                     /locus_tag="IVV98_002785"
     CDS             complement(543..2048)
                     /locus_tag="IVV98_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7808364.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="IVV98_002786"
     CDS             complement(2045..2731)
                     /locus_tag="IVV98_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7808365.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IVV98_002787"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IVV98_002787"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP7808366.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          730 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa agggatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat a
//
LOCUS       DACCVH010000140         4415 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.146, whole genome shotgun sequence.
ACCESSION   DACCVH010000140 DACCVH010000000
VERSION     DACCVH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.146"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            58..912
                     /locus_tag="IVV98_002788"
     CDS             58..912
                     /locus_tag="IVV98_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7808367.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="IVV98_002789"
     CDS             1009..3258
                     /locus_tag="IVV98_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP7808368.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4415
                     /locus_tag="IVV98_002790"
     CDS             3261..>4415
                     /locus_tag="IVV98_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7808369.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          805 g         1429 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DACCVH010000141         4269 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.147, whole genome shotgun sequence.
ACCESSION   DACCVH010000141 DACCVH010000000
VERSION     DACCVH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.147"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            75..503
                     /locus_tag="IVV98_002791"
     CDS             75..503
                     /locus_tag="IVV98_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7808370.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="IVV98_002792"
     CDS             490..732
                     /locus_tag="IVV98_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7808371.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="IVV98_002793"
     CDS             complement(1032..1247)
                     /locus_tag="IVV98_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808372.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="IVV98_002794"
     CDS             1354..1668
                     /locus_tag="IVV98_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7808373.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="IVV98_002795"
     CDS             1772..2950
                     /locus_tag="IVV98_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7808374.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="IVV98_002796"
     CDS             3353..3646
                     /locus_tag="IVV98_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP7808375.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1460 a          644 c          822 g         1343 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatagt agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaattt
     4261 aagcaatac
//
LOCUS       DACCVH010000142         4138 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.149, whole genome shotgun sequence.
ACCESSION   DACCVH010000142 DACCVH010000000
VERSION     DACCVH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.149"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            98..631
                     /locus_tag="IVV98_002797"
     CDS             98..631
                     /locus_tag="IVV98_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808376.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(757..1434)
                     /gene="nth"
                     /locus_tag="IVV98_002798"
     CDS             complement(757..1434)
                     /gene="nth"
                     /locus_tag="IVV98_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP7808377.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1441..2139)
                     /locus_tag="IVV98_002799"
     CDS             complement(1441..2139)
                     /locus_tag="IVV98_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP7808378.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2407..3591
                     /locus_tag="IVV98_002800"
     CDS             2407..3591
                     /locus_tag="IVV98_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP7808379.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3597..4040)
                     /locus_tag="IVV98_002801"
     CDS             complement(3597..4040)
                     /locus_tag="IVV98_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7808380.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT         1098 a          801 c          665 g         1574 t
ORIGIN      
        1 cttgtttata attaaatcgg ctaaatacac actagtcttt tatttagtgc cacttcttaa
       61 taatcccatt gttattatca aataaaaaat acaatatatg gttttgaata attttttgaa
      121 agaaggcttc attttgagtt atctgatagt atgcttaatt atcataattt gtctgcacca
      181 tcttttttta tcgaaaacaa tacctcgtta ttccaagaat aaaaaagctg aaaaattttg
      241 tttattatta aataaattta ctttaattgc tcctatcctt gcatttatta ttttttctgt
      301 acttttaagc actactctta aaggaaaatt tatggaaaga agctctcatg caatgattct
      361 cactttttta tggttgttgt tcaccagaat ctatattttt ctgatgagcc tgaaaccgcc
      421 caaatccatt agtttatgtt tagttataaa tggtattttt ttattatcac ttatcatttt
      481 tattacacct ttagatagat acgtcactta tttatataat cctttggaat actggactta
      541 ttttataggt atattggaag gcattatttt ctacatcggg tattttccca ataaaaataa
      601 caacttttat ttttatcgca ataaattgta ataagttacc atcctagcta ctgagtatgt
      661 acatttactt tttcatgcaa aaaagataaa cgaaacagct tttctccata ataacaagat
      721 aattcataca tttatttgca attaaagaaa ccacgtctac aggcgtggtt tcttttttag
      781 cgccttttct tttagacgca tccgattttt cccatcttga catattgata gcaaaggaca
      841 tacctcgcac ttgggatttc ttgccgtgca atgatatcta ccaaaaaaaa tcagtgtatg
      901 atgtgtcttt acccataatt cttgtggtac tttccgcatc agtgtttctt ctacttccat
      961 gaccgtagca tctagtttgc agatcctcag gcgttttgag acacgttcca cgtgggtatc
     1021 tactgcgatt gctggtatcc cgaatgcatc ccccaatacg acatttgctg tctttctgcc
     1081 tacaccagga agagacatca attcttctct tgacgttggc acttgcccat cgaaacgttc
     1141 aatcagctgc tgtgcacacg ctttgatgtt ttttgcttta tttcgataca aaccaatcgt
     1201 ttttatttta agaatgattt catcgattga agcttctgct aacgcatcgg gtgtcggaaa
     1261 agaggcaaac aaatctggcg ttgctttatt cactgataca tctgtcgcct gggcacttaa
     1321 gatcactgca atcaataact caaatggatt attgtgcttg agttctccat gtgcttcggg
     1381 aaacattcca tacatcgttt ctagagcttc cattgttttt tgtttgctta acatattccg
     1441 ctactcctcc aaccaatttt tcagtgagac tttcggcaat tcttcttgtt gagctgactg
     1501 ttctacttct ctttgaagaa gctgctgttt tcttcgtttt tggtcttctt ccacttgttg
     1561 ttttgtacgt agattttttc tttcccacga tagcaaaatg cggtcaacgt aattaaaact
     1621 ataagcctga tttaatacgg cttcccgcag tgctagcttc aaaatttccg gctgataatg
     1681 gtcttcttct agccattgtc cgatccgctg gaactcgatc gaagaaagcg ggcgtccaaa
     1741 ttcttgttca aataattgat acactgactg gatttctttt tcttgtgttt tttcttcgta
     1801 ttttttttct tgtgttttta aatactcacc taatagatca tagatggggt aaagattata
     1861 tcgatctgct tttttaccgt tgacaatcgt cgtttctatc ttgataaatc catttgttac
     1921 gagacgatcc agtatttgaa aaatctgatc ttgtttgatt cccatatcca tagcaatcat
     1981 ctgcaaatca gggaaagtat ctccttcaag ctgtgccata tgcaactgta gaacaaataa
     2041 aaattcttca gattgtagac cgatcctatg ataattttta agtaaaagat tagatatgac
     2101 tgtttgtcca gcgcttaagt aattttctaa attcaacatg atttctcctc cgctcaatca
     2161 cagtatacgt aaaaaaaaca tgggaagcaa gaacaggttt cttttctatt tacttcactg
     2221 atcggtcaga tttacaatgt cgtctacttg atttttgttt gttcatgttt ttgatgcgta
     2281 tcttcacttt tcggaataaa taaattaagt agatttcgct gttccttaga atgttgacaa
     2341 ggaaacaaaa ttactataca ctatttttgt ttccaagtta acattattgc ataaaggagt
     2401 ttttacatgt acagtttcac aaataaacat tctaaagttt ttggatacgt ctctgtctta
     2461 ttcactggat taggatttac tatcgtcagt cctgtacttc cgtttttaac gctgccttat
     2521 tctcactcca tacatcagca agctttctat atcactttgc tcatgtctgt ttatgctcta
     2581 gctgccttct tatctgcccc cattctcggt agcttaagtg atcattttgg gcgtcatccg
     2641 atccttatta tcagtttatt aggatcaagt atcggatatt tgctttttgg tttaggaaat
     2701 tcgatatgga tgttgttcct tggtcgtatc attgaaggat tgacggcagg agaaatctcc
     2761 accttatatg cttactttgc cgacatcacg gaacctaatg aaagaaccaa agtttttgga
     2821 tggatgggtg ctttagtcgg tataggaaca acgctgggtc ctattatagg gggtctatta
     2881 gctgagttgg ggaattctgt tcctatattt attggagcac tctttacttt cttaaatgcc
     2941 gtttatggct acacatttat gctagaaagc cttccaataa aaaaacgttc agtagattta
     3001 agtttctccc atgtaagacc ttttcaccaa ttacaacaat tattcaagat ttcatccgtt
     3061 attcctttat tgacagcagg ttttgctgtt tggttggcag ctggctctct tcaatctatc
     3121 ttttctcaat tttcgattga cgcctttcag tggaaggctg ggttggttgg tttaagcttc
     3181 tctttgattg gaatcttgga tactgtctcg caattgttca ttatgcctcg attgctcaaa
     3241 aaattttcag aacagcagat cacaagaata gggatgttca gtgaaatcct cgcctatcta
     3301 ttcatcacat tatctggaat tcttctactg ccgattttgt ttttatttgg gattatctgt
     3361 tatggtttcg gtgattctat ttttactcct gtattcaatg gccaactatc caattctgtc
     3421 tcagataacc agcaaggtct tgtaatgggc ggtacccaaa gtatacaatc tctatcgcgc
     3481 gtcatcggcc cgctaatcgc aggacagctt tatgctgcag caccatttct tccgacggta
     3541 ttcggatttt tgcttatgat ttttgcctat tatcactaca ataaaaaata gtagcttcat
     3601 ttgctacttc gtataaattc tctgtatcga ccgataaaac gaaatactgt gtcaaattct
     3661 tcttttgaca tattttcaaa tacagtagca tctcgctgta cccatttttg atggagttgc
     3721 tcgtgtctat tccttatttt ttgtccgatt ggcgtcaatt gaaaatagat ttctttttta
     3781 ttctcttcgc tttgataagt gtttatgatc cctctagcta tcagtttttt tgttagctta
     3841 ctgatggctc ctctagtcat gtaactagca ttcgctaatt ttgtcacgtt aggatcaggg
     3901 attttcccga tatgttcaat cacttctagt tcatttagag taaatcctgc aaattctttt
     3961 tccatttctg gtttattacg atgaataatc tcattagcta aatccagata ttcttctatt
     4021 agcagttgtc ttttatccat ttctacacct tctttttctt tcattatatt gtttttttgt
     4081 ttcctattca acaaagataa aaatattttg taggaaaacc caatctgaaa ccaagaaa
//
LOCUS       DACCVH010000143         4070 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.151, whole genome shotgun sequence.
ACCESSION   DACCVH010000143 DACCVH010000000
VERSION     DACCVH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.151"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            86..1435
                     /locus_tag="IVV98_002802"
     CDS             86..1435
                     /locus_tag="IVV98_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7808381.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="IVV98_002803"
     CDS             complement(1563..2153)
                     /locus_tag="IVV98_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP7808382.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="IVV98_002804"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="IVV98_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP7808383.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DACCVH010000144         3876 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.152, whole genome shotgun sequence.
ACCESSION   DACCVH010000144 DACCVH010000000
VERSION     DACCVH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.152"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(716..3865)
                     /locus_tag="IVV98_002805"
     CDS             complement(716..3865)
                     /locus_tag="IVV98_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP7808384.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DACCVH010000145         3641 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.153, whole genome shotgun sequence.
ACCESSION   DACCVH010000145 DACCVH010000000
VERSION     DACCVH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.153"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..355)
                     /locus_tag="IVV98_002806"
     CDS             complement(<1..355)
                     /locus_tag="IVV98_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808385.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(615..1163)
                     /locus_tag="IVV98_002807"
     CDS             complement(615..1163)
                     /locus_tag="IVV98_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808386.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1164..2021)
                     /locus_tag="IVV98_002808"
     CDS             complement(1164..2021)
                     /locus_tag="IVV98_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7808387.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2307..2593)
                     /locus_tag="IVV98_002809"
                     /pseudo
     CDS             complement(2307..2593)
                     /locus_tag="IVV98_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2583..2912)
                     /locus_tag="IVV98_002810"
     CDS             complement(2583..2912)
                     /locus_tag="IVV98_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7808388.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2989..3261)
                     /locus_tag="IVV98_002811"
     CDS             complement(2989..3261)
                     /locus_tag="IVV98_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP7808389.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3261..3524)
                     /locus_tag="IVV98_002812"
     CDS             complement(3261..3524)
                     /locus_tag="IVV98_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7808390.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1063 a          742 c          460 g         1376 t
ORIGIN      
        1 taaatgttct tactgcctct tccacactaa tttcttcgtt caatttcact aataatactt
       61 gatctcgctt attataatcg ctttcattta tcctaagagt caaatctttt tccaccataa
      121 cttttacacc caataaattt tgcggtttat ttttctctgt tgaaattctt tgtgtagcct
      181 ttaaactgac aattagctca ttgggtacat actctatttg agagtcatct aattggctca
      241 taatcctttc tttttggtta gtatctgcag ttacttgttt agtatgagcc atgaacccaa
      301 acatactcac cccaacaacc aatcctaaat atattttctt tttaaacttt ttcatctaca
      361 tctcctccta atagttttat tttagagtta gctctattac ttatttacta actcaacaac
      421 agattatcat acacttgtta atgaaatcac aatatctcat taaaacacac cctaaaatca
      481 taaccgttcc tatgctcatt ttttggattt tttaatcacg taaccagaaa aataaatccc
      541 ctctatttca cgcaaatcaa agaagaacta agtaactacc gtttaaaggt agttacttag
      601 ttcttctttg attattatct aactttatta ttcattcccc accctttgcg cagtgagtct
      661 tcggtatctt gttttatctg actggtagtt cttattattt ctccacgatc atctaattct
      721 ggaacaattg gatatttttc tctgaacaag tctagttctt tcaccacgtc attaaacaaa
      781 tcttgcttat cttcttgcgt aagattctgt ttaatatact catctaaagc ttttctaagc
      841 aattcatctc ttgtcatatt agtctcatac ttttctacta aaactctgga agtcgcattt
      901 aacaaagtcg acagttttaa aggatgcttg gtggaataaa ccttatcaaa ctttctgatt
      961 ggtgcgccaa ctttttttgt tcttcctcta ctctgtcttt caacattgga ggaagttttt
     1021 atttcttgaa cttggtgcac ttctaattgc ttattttcag atggtgtaat tgcttgctgc
     1081 tttttctttg cttctgcttc tttttttatt ttggcgagtc ctttgttgtt cccaaaaata
     1141 tcaagtcctt tgatgtcagc caattactcc acctccgcat accaattctc gtgttcttcc
     1201 aattctttca aaatactgat aaataattcg tggcttttgc gatcccattg ttttaagaga
     1261 cctttctttg tcttctccat cgtaatacct gatccgtcgt atcgttttaa gcgcgcattt
     1321 ttgagtacaa catttttaat caaatgttcc ccataaatct cttgggcttg tttatacatt
     1381 tcctgatcta ctgcgtcacc gctttccaac atgaaaggaa taacaccagc aacatataaa
     1441 tttgtatcaa attctttcac aaaaaagtcc atatactcaa gatattgcat cgcatttctc
     1501 atcgatttta cttgggtctg taagacgacg attgcccaat ccgcaatgta catcgcggat
     1561 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
     1621 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
     1681 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
     1741 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
     1801 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
     1861 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
     1921 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
     1981 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
     2041 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaag
     2101 atatatatgt actaccttat aattaataag taaaaggtag tacataaata aggaaaagct
     2161 gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt atcgagaagc
     2221 agagaatact cgcgacttta gtcatgtaga cgaatcagat tttcgataaa aaagaagccg
     2281 tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc ataaaagttt
     2341 tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc gtaagctact
     2401 ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa atccccagtt
     2461 ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaatt caaaaatttt
     2521 tctttcaatg gcttctcttt tagcttttta aatacttaat gacatgtttt gaaggaacga
     2581 tttcataagc caatttctgt tgccaactcc tctttagtca ttactttaga attagtaagt
     2641 gtatcttcag caatatctct aaaggaagaa tgcattttgt tttttctatt cttaaattct
     2701 acaagaatct catctttatc gtagccttct gcaattatat cagacaaaat atcttcgcta
     2761 aaatcataaa attctttttg tggttcaaca aattcataaa gaataccatt ctctaccaac
     2821 tttgcttcaa cttcgactcc attaggaaca ttaaaatctt taggtactgt caacatgatt
     2881 gaattgcctt gttttcttgt ttttgtaatc atttaaatcc ctcatttcta acagtatgta
     2941 attacttagt aaatacatta taccacgaga taatgtattt acaagtaatt actgtgactc
     3001 gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca tcttcatcta ccttataaac
     3061 aacccggtgt tgtctattca atcttctaga atacctacct tcatgtgtag gttttaactt
     3121 ctcaaatgat tgggtaggga gatagggatc ttcctttaaa gtctgaataa ccttctcaaa
     3181 ttgaggtttc aaattagact gtttgatttt ctttaaatca gctttagccg agtttttaat
     3241 catcacagaa tagttattca ttataagtta tcccaatcaa tttcatcaac attagtaaat
     3301 ccactatcat ctttttctcg cttacgaaca acacccaaag tgcctatttg ctcaagtaat
     3361 agcgtttctt tgattgcttt ccaatcatcc aaaccaataa gcaccgcatt attttcactg
     3421 cgctcactaa tgatttcaat ttccgtatga ttctcattta catctttcaa caacttataa
     3481 aaatttttcc gtgctgagct aggatttaag actgtttttg ccatatctac tccccctcta
     3541 atttatatct ccattctaac gtacttaatt aagtacgtaa attcgattgt tttgtttaaa
     3601 ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc c
//
LOCUS       DACCVH010000146         3583 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.154, whole genome shotgun sequence.
ACCESSION   DACCVH010000146 DACCVH010000000
VERSION     DACCVH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.154"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            158..1897
                     /gene="yfcC"
                     /locus_tag="IVV98_002813"
     CDS             158..1897
                     /gene="yfcC"
                     /locus_tag="IVV98_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP7808391.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2054..3238
                     /gene="iadA"
                     /locus_tag="IVV98_002814"
     CDS             2054..3238
                     /gene="iadA"
                     /locus_tag="IVV98_002814"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP7808392.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3349..3552
                     /locus_tag="IVV98_002815"
     CDS             3349..3552
                     /locus_tag="IVV98_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP7808393.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
BASE COUNT         1154 a          594 c          826 g         1009 t
ORIGIN      
        1 aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat tttctaataa
       61 attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc attttttatt
      121 catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa attcttcagg
      181 aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca ttatttttgg
      241 tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt tcagcacgca
      301 agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt tacgtcaaga
      361 ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat tagaagaact
      421 gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat tggaaaaagt
      481 cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct ccttgacaga
      541 tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa aattgcataa
      601 aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa attttgtttt
      661 tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg cattgatcct
      721 tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg caggtatcta
      781 tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat tattctttgc
      841 tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat tctcaatggt
      901 gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa ccgtgactta
      961 tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg tagcggtggc
     1021 tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga ttatgtgggt
     1081 agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa tccgtaaaaa
     1141 accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata tcaaaaagac
     1201 atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag agatgttagt
     1261 tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc cagaaatcgc
     1321 ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt tcaaattaga
     1381 tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg atttagctgg
     1441 tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag gatctgatgc
     1501 atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt tgaccggtgt
     1561 tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca acttggttgt
     1621 tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac tggcagattt
     1681 agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag gttttatgga
     1741 cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac ggatcgaatg
     1801 ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt taggaactat
     1861 tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg taaataaaaa
     1921 agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa aatcaaagga
     1981 gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat acttaaagaa
     2041 agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag attacttagg
     2101 aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac agctagaagg
     2161 cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac taaccccggg
     2221 tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt atcaaaatcg
     2281 aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag ttgtcggttg
     2341 tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag cgaaaggtct
     2401 ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc cggtaaaaac
     2461 agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg gaatcggaga
     2521 aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg ctcgtgcagt
     2581 agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca atgtccactt
     2641 aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa cagaaattcc
     2701 gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg aagcttgcgt
     2761 ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc ctgatttttg
     2821 ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga tcgaggaaga
     2881 tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc cttattttga
     2941 tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc tagtagggat
     3001 caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag ctataaccag
     3061 taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg gtgctgatgc
     3121 agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg ctaaaggaga
     3181 aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa gtttttaatc
     3241 aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga
     3301 tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta
     3361 aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc
     3421 aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac
     3481 atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac
     3541 gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaa
//
LOCUS       DACCVH010000147         3405 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.155, whole genome shotgun sequence.
ACCESSION   DACCVH010000147 DACCVH010000000
VERSION     DACCVH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.155"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            154..1194
                     /locus_tag="IVV98_002816"
     CDS             154..1194
                     /locus_tag="IVV98_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP7808394.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2018..2350
                     /locus_tag="IVV98_002817"
     CDS             2018..2350
                     /locus_tag="IVV98_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP7808395.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            2969..3310
                     /locus_tag="IVV98_002818"
     CDS             2969..3310
                     /locus_tag="IVV98_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP7808396.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1265 a          460 c          646 g         1034 t
ORIGIN      
        1 aggtagtaca taattcattt tatttctgat tttaggtagt atttaattaa aaaacagttt
       61 taatgcgttt gcatttttta tttatctttg ctattttcga aaagagtagg taattttaca
      121 taaataaaac aacgtgaaag tagaggatct acaatgactg attttaaatt ttttaaggcg
      181 gatagagttt acaacgaatt attttatcaa tttccaaaag tctttattgt ttctgacgaa
      241 tacaaaaaaa tgaaagattc aactaagatt gcctatatgc ttttaaaagc aagattagag
      301 atcgcaatca gcaaacggca aatcgatgaa gaaggtaatg tttattttac ttatacgaca
      361 aatgaactat gtagagtatt aaactgccaa aaacaaaaag cgatagcaat caaaaaagag
      421 ttggaatcct ttggtttatt attacaaaag cagatgggat ttaacaaaca gttagggaaa
      481 aataatccta atagactata tctagcagaa ttaaaagtct cagaaaatga tatctactta
      541 ctcgaaaaat ttgatagaga gaatagggaa aacgttgata aatcagaggg tatgaaaatc
      601 atacccaccc tcgacgaaaa atcagacgct gaatcccttg gggctcaaga gggtatgaaa
      661 atcataccgt gccaaaacgt tgataaatca gagggtatga aaatcatacc agaacttaat
      721 aataatatat tagacactaa tagacacaat atagacactg aaaaagaccg cctacaagat
      781 caattgttgt tagacaattt tgagacaatt atgacaaacg acagcattgc tacgtttgtc
      841 cctgaacgag tattaaattt gataaaaaca ttttcttcaa gttacagtga agctcaaaaa
      901 accgtccaga ctattcataa tgcaaagaaa aaagctgaaa tagaaagtga tatttcgata
      961 gtttttgaag aactcgatag ttattatgtc aatgcagaac aagaattata cacgacactg
     1021 ttaaaagcct atcaaaaatt aaaaaccgaa aaagtcgaaa atatccagaa cctgattttt
     1081 gtctatgtaa aaaattggtt tatcgaaaaa ccaatagctg ctaaagtatc aagtgaaaaa
     1141 cgtttgaatt atgcaagctc cccaagcact attacgaaag actggttaga gtgaaacttt
     1201 actgacaaag tgattgttgc ttcatggagt aacattaaaa ttaaaaattt tttattattc
     1261 taattatatt acgaatatta caaaataata gctattttaa tagaatttat aagttaaaat
     1321 attatgataa aaatcacaaa cgtagccttt tacgtcataa gtgttaaaag aaataattaa
     1381 tttcaaatat agaaaaggga acgtatgttt gcatactcct tttttttgag ttataataat
     1441 acgcgaagag agataatttc attatttaaa caagctaaaa atcttgatat tacttctttt
     1501 caggcaatac gaatattatt cgcttacatt ttttgtataa atttaattgt ctgctatgct
     1561 tgtgatgaat tgattttcgt tttgcacttt tggatgataa atttggacaa ttgaaaatac
     1621 aaaaaaaaga aaggcggtat gaactcggaa ggctggtaac cttcgtcagc gttcatacac
     1681 ggcattaaga tttggccctt aatgcgttaa cctttcagtg ttacggtatt acccgcaatg
     1741 gatttagtat aacagatatt caaaagtgat accacttttt ttggctgtgt taaggttaaa
     1801 aatacgtgat attacgatga atctatgcct aagcataatg ttataaaaat gtccgtgtgg
     1861 ctctttgccg tatgacgaac gctgaaatta gagggaacgc atgtttggat gcgttccctc
     1921 ttttttgttt gtcatgaacg aaaatcaatt ctctattttt gaaaaataac aagaaaaact
     1981 tgttaaaaat atttaaagaa attgggtggt ttattttatg tcatatacag gaattttgag
     2041 tctcaaagat atttgtcact acggtaaacg gtgtaccgct acagagaaaa tcacgaagaa
     2101 actatcaact ggccaaagta aaaccgttgt gcagtgtaag aaatatataa tccagaaaga
     2161 caaagtctca gaggaaatga tttattacat tgggaaacaa aagcaaataa ttttaaaaga
     2221 tcctatcccc ttaaaagagc tatatccaac aatcaaacat gtttatgacc aaaacggtgt
     2281 actgattggt cgaagaaaaa atggagtctt gcgttgtacc gcaaaaggga tggggcgttt
     2341 gatcggctga attgatcatt ctcataactt gtattttatc gtttttcgct tgcttgaaaa
     2401 tattgtcgag acttctaaag gaacttagag tcactagaaa aataaggagt agacttgatc
     2461 tatcaacaat tcccttcggg gagtgacggg gtaggtttta acgattggta acgtaaaaaa
     2521 ttggtcaatc gagtaaatgc gcttgtttgg atagtggtga aatgaatttg tgtaaataat
     2581 aagcgcagag taaacaagag ggaatttaga agttagacaa gttagaatag cgtctagatt
     2641 aatcatgagc agctactaag ggatctagac tttgacgcaa actcatggaa taaggagtag
     2701 gtcttctcgt aatggggagg acgcacaaga aattgtgtcg tgtgctgcag tacatgtaga
     2761 tacttgcgag gacgttgatt attggatcaa tcgagcattt accgctgtct actagggttt
     2821 ctcgtttcgg acgccataaa cgagtcgaaa ttttttatgt atttttaagt aaacgaaaaa
     2881 cgataaaata tgaacaagtc ctgaataaag tgaaaaaatt gatataaaac atagagaaaa
     2941 tgaaatttac gtaatggagg aatgacaaat gaaaaattat gatccgaata tacgattggg
     3001 cacacatact attaaggttt ctttccaacg ttgggattac aaaggatttg tgacgtttag
     3061 aaggggcgga aattgtaaag gattagatgt tttagcatta gacgaggatg atttatacga
     3121 tcaaacattg actgataatc caattggatt cggcttgcta cctgaagatg atgaaggtaa
     3181 tgaatggttt aaaatgacgc ttatgaatga taatggagac gaattatctg ttgaagatac
     3241 ttggtcatat ttgagtgatt atattgtcag ctttgaaatc attgaatttg tagcggataa
     3301 agaagaataa aaactggagg aataaatttt acagataaag gcttagaagg agtcacgacg
     3361 attaataaaa aggtagtatt accttaggca ttgagtaagg aattt
//
LOCUS       DACCVH010000148         3336 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.156, whole genome shotgun sequence.
ACCESSION   DACCVH010000148 DACCVH010000000
VERSION     DACCVH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.156"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(451..1761)
                     /locus_tag="IVV98_002819"
     CDS             complement(451..1761)
                     /locus_tag="IVV98_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP7808397.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="IVV98_002820"
     CDS             complement(1773..3191)
                     /locus_tag="IVV98_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7808398.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
BASE COUNT         1033 a          676 c          515 g         1112 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataaga
//
LOCUS       DACCVH010000149         3284 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.157, whole genome shotgun sequence.
ACCESSION   DACCVH010000149 DACCVH010000000
VERSION     DACCVH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.157"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(100..1119)
                     /locus_tag="IVV98_002821"
     CDS             complement(100..1119)
                     /locus_tag="IVV98_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7808399.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1116..1340)
                     /locus_tag="IVV98_002822"
     CDS             complement(1116..1340)
                     /locus_tag="IVV98_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP7808400.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1337..1630)
                     /locus_tag="IVV98_002823"
     CDS             complement(1337..1630)
                     /locus_tag="IVV98_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808401.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1667..1804)
                     /locus_tag="IVV98_002824"
     CDS             complement(1667..1804)
                     /locus_tag="IVV98_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP7808402.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1806..2237)
                     /locus_tag="IVV98_002825"
     CDS             complement(1806..2237)
                     /locus_tag="IVV98_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808403.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2251..2745)
                     /locus_tag="IVV98_002826"
     CDS             complement(2251..2745)
                     /locus_tag="IVV98_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808404.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2745..3194)
                     /locus_tag="IVV98_002827"
     CDS             complement(2745..3194)
                     /locus_tag="IVV98_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808405.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT          884 a          688 c          529 g         1183 t
ORIGIN      
        1 tgggtgatag tgaagatatg cgataacatc actattttat cgaatgattt ttatagttgt
       61 caatatagtt atgtaatgct cctcaacgag gagctatttt tatcgtttag gaatatttaa
      121 ataccaacgt ttgtcatgga aatcttgcgc accgccttta gtgtttccct ctggatcatt
      181 cgttgcccgc atcatgacat agactttctt attagggaag ttacgcatgt taaaagatac
      241 atgatagcca acatttccag aagtattata agcttgattt acatctgctc tataaattcc
      301 atcagctctt actcgagcta attctttccc agtattgtaa tccataatga agatatactc
      361 gtatttatag ttagcaatgt gccatccagc tacatgcaaa tttgcatttt cgatttctcc
      421 aaactgatca atgtgggcgt aattcgttcc atctgtcagt gtaggattag ctgcaccagc
      481 tcgtgttgga tcaatgacag gcttgttttc agaagttgtt ggattttcat cggtaaatcc
      541 atgagctaaa tcatatgcta atttttcttt acttacgccc atttcagaaa gataaccgta
      601 aggatctgta tgatcgcccc agatgttttg tgttacccat aaatgcgatt tgattcccgg
      661 ttggttataa ggagtgtcca acgttaatgg aataccatat ttcattgctg aatctctagc
      721 caattcaacg tatgccttgt agtttttctc aaacgttgct ttatcatgtg tgtgttgtaa
      781 ctcaatctgc acaggactgt tggcattagc atacgaacca gcaccgtact gtacataacc
      841 aggttgaccg acttgataaa caattccgcc gtctcccaca atataagcag tataagcgct
      901 agtccatgaa cgttgcatat actgcgcttc attgcgtcct gttgctgttt cattagccgt
      961 ttcatgcagt aaaatatact gattatttgc tacttgtgag ctaccttcat ttgcgcccaa
     1021 attaaattca ttgttgatag tataggcaaa tccgttaatt ggcaataaaa aaagagccgt
     1081 taacaggctc atcgcagtaa tagtaatttt ctttttcatt tgtttcctcc ttcttcgctt
     1141 tcagccgaga acattttgta ggttcgattt gatacaccca acacactccc taaaaacgcg
     1201 ccaaaaccag taatgatgac aacacagata tctgtgtact gccaattgag cgctttacca
     1261 actaacccca cgaaagtagc tagtgcggga ataattacca gtgcgaacca ttttagtact
     1321 tcgaacgttt tattattcat tttcttctct ccctaaacaa agttttgatt tgttgcgtgt
     1381 gttccaccaa tttttctgta tgtgtatcta atctttcatc gtgtttcttt agttcttcat
     1441 gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt agtcagcaaa tctaaattgt
     1501 ggcttacttt tgaaagagtc tcagtaattt tcgagaaaga tgcagcaatc ggtctaatta
     1561 ctaataaaat caaagaaacg atagcggtta ttgatcctgc tatcattccc cattccccta
     1621 aattaatcat gtgacaactc ctttacctta aataaaaacg catcaattaa gatgcgctct
     1681 tatctttatt aatgatttta tctgcttctt cgtctgtaat gcataatgga acgaaaacca
     1741 ttacttgttc gttagtgaaa cagccccagt catacattag tttgatatct tcatatgaat
     1801 acatgttact tcccaccttg taattgtttt ttgatttctt cgatttcctt ggtattttgt
     1861 acagaagcaa gcatcgtttt tgaattcaac tgcgctaaac tttctgactt ttctttcaat
     1921 aagacatttt cttgcttgat tgctacattg tttagcattg ctttagaatt tagctgtttc
     1981 aattcatcat tttctgcctt cagcgtttcg tataatgcct taatattagc caattcatct
     2041 acgctatcaa cagcattccc ttttttctct tcttcagtag ctaactcaac ccactgtttt
     2101 ttatcaaaat caaatcttgg tctccagtta ggaactggtg gtttaatctc tgtacagttt
     2161 tcagggatat tttcttgatt gttcaaaatg atttgctcga atccgtaagg cttgattgat
     2221 ttgtaaacta ctttcattag atttcctccc ttaaattgaa taagtgataa caaatgaata
     2281 agctgatcca taacttgaat ttcttctcca tttaatggct ccgtctgcgc caatagatag
     2341 ttgagcactg ttcaaagtag aacggtctat tgacccaacc agttgttcaa aactaattgg
     2401 tgtccgatag ccttctggaa cagttaaaat aaccgaatca ttcccgccac tactttttcc
     2461 gtttaaagcc acaaaatata tagaaactgt ttttccttca cgataaagct ttgctgtccc
     2521 tgtattaccg ttagtgacaa ccagatttac cacttcatat ctgttatcat cagtcgtcaa
     2581 aacacgttta ttattgattg ttacagaacc tgaaaaattc ttatgtcctg caatggcttg
     2641 gtctccatct gtctgcacca atgcttcttt accatcaata gcttctacat gcgtttttaa
     2701 gtatttagca actccgtctt cttttaattg aacaatatca gccattaaac cgtccccact
     2761 ttctcaaatg taatattcgc taatccatca agtttcactt tatcggttgc tgacattaaa
     2821 cctgctgtcg tagttgtagc attacctgga tttttctgtg ctccagctgc aattccatcc
     2881 aacttagttt tatctgtgga cgacatcaac ccatttgctg tagttgtagc tacagctgta
     2941 gttgtggcat ttattccagg atcaccttta tctccctttg gtaaaacaaa attaaatcta
     3001 gctgcagatg atgttcctac attcgtaaca gaagcggttg aaccactaga aacggttcct
     3061 atggtaattg ttgctgcttg gccaggatcg cctttatctc ccttcaccgt tgttggtttg
     3121 ccttctatag cattccaatg agtttgtgga taaacctgta cattgctttg ttttattttt
     3181 acgatatctg tcattctcta tacctcccca attttttcaa aagtaaaatt tggaattctt
     3241 tcgtttgtgt aattttctgc ttgatttaca gcttcttgga attt
//
LOCUS       DACCVH010000150         3094 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.158, whole genome shotgun sequence.
ACCESSION   DACCVH010000150 DACCVH010000000
VERSION     DACCVH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.158"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(276..455)
                     /locus_tag="IVV98_002828"
     CDS             complement(276..455)
                     /locus_tag="IVV98_002828"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808406.1"
                     /translation="MEKDIYKQLTRQIQKEKEKGLLDHLDELELKADEINKNRMSAKE
                     KGIKLKDSSLQSDKS"
     gene            complement(579..824)
                     /locus_tag="IVV98_002829"
     CDS             complement(579..824)
                     /locus_tag="IVV98_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808407.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLKYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1169..1453
                     /locus_tag="IVV98_002830"
     CDS             1169..1453
                     /locus_tag="IVV98_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808408.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1456..1872
                     /locus_tag="IVV98_002831"
     CDS             1456..1872
                     /locus_tag="IVV98_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808409.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNQPKNHQKGTNKTVTSSNFDPTKFLKR"
     gene            complement(1960..2682)
                     /locus_tag="IVV98_002832"
     CDS             complement(1960..2682)
                     /locus_tag="IVV98_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepB"
                     /protein_id="HAP7808410.1"
                     /translation="MNKNITKARHFGFLLYPESIPENWREQLESLGVSMAVSPLHDMD
                     EKTNKKDWTSSDVIRNGKHYVKPHYHVLYIARNPVTIESVRKKIKRKLGNNSVAHLEI
                     IDHIKGSYEYLTHESKDAKEKNKHVYDKKDILHINDFDIDRYVTLDESQKKELRNQLF
                     DLVNHCGIVNMKELAAFLDWRGQEYGITNQRDVVDVIASNSNLFRMMFDANYQNGFRP
                     QYAKRIDSETGEMIEGVNKHVE"
     gene            complement(2763..2912)
                     /locus_tag="IVV98_002833"
     CDS             complement(2763..2912)
                     /locus_tag="IVV98_002833"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808411.1"
                     /translation="MAESERLVVILPSEIKRKLEEKAKDKSLSMSTYVKLLVTEDLKK
                     SEKGN"
BASE COUNT          943 a          622 c          443 g         1086 t
ORIGIN      
        1 ccccccagat tttccaaatt ccaaattttt tccaaaaatt ttccagcgct atcgctcggc
       61 aaatcaagac cgtacctttt tgaaaaaagg caccccaaaa actttccact cgccgttaag
      121 gcgtcaagaa cgttccctat ggtcaccttc ttgtgtttcc agcttttggg ttttgtttat
      181 agccgtcaac tccttaaagc ctcaaagaga cgctaagagg gcttattagc ctctctaagc
      241 gtctctaatt cgatttaccg ttgaccgcac gttatctagc ttttatcgct ttgcaacgac
      301 gaatctttaa gttttatacc tttttctttt gctgacattc tgtttttatt gatttcatca
      361 gcttttagtt ctaattcatc taaatgatct agtaagcctt tttctttttc cttttgaatt
      421 tgtcgggtca attgtttata aatatctttt tccatccccc atcgcctcct taaaagctat
      481 tattattcga tttaagacgt tttatttagt ttttggtgta tttcattggt ccaagctaaa
      541 aaactcttag aagcgatttt agagccattt aaacccactt aattatattc tccatgaaat
      601 tcgctccatg cgtcaaaagc tgcgtctgaa attccgccgt cttcgttcac tagttgcatt
      661 aatttttcca acgatcgttt tctttcgggc gtcatatttt tatatttcaa caatttttcg
      721 tctgttaaat cgaacttgat tgcttgaatt gcttgctcta atttttctaa gttttgaaaa
      781 tattcgtaag gaaatttttc cattttttct ttctccagtc tcacaatttt tctagaaata
      841 aaatcacttc tttgccgtct atactctcaa aaaaaatgtc gtttgaaaaa ctaaataaat
      901 ttttgatcgt gcatttttaa atttggttat cgatcacacg tgcagcactc ccccccgaat
      961 tttaaagagc ataaggaaac gtggtatcac tttcttacga aaggtgctag ataggctgtg
     1021 cctatcacgt ttctttgaaa aaaatttgat atcacttttt cgccatcgtg gatagcttat
     1081 gtatagtatt ttggcaaaaa acagctatac aaatatagta tttgtatggt atacataaat
     1141 tatacataat tgcaaaagga gattttttat ggacatttta gttcggaata ttgatccaaa
     1201 gtttgttgca acaatagaca aacgttgcca agaactcacg aataaaacag gagaaaaatg
     1261 gagtcgaaat aaatatctaa aagttttaat cgaaagtgat tttgaccgtc aacttacgac
     1321 ttacaaaaaa gaccaattcg atttattgct cgataaattt attgctatcc aaacagaaaa
     1381 tactcaaata ttaagcgagt atgtctacac aaataatcaa atcattgaaa tgcttatcgg
     1441 aggaatgata taaccatgag aaaaacttct gtccaaaaac atgttacttt gtaccctagt
     1501 catgttgacg ttttagattc catcatcgaa aaaaatccag atatcaataa ctactcggaa
     1561 gccattcgct ttttatgtat gagttatgaa cccgatacca acacgaccac taccagcaat
     1621 caggcaaaac taaatgctat gggaaaagaa atttccatca tgactgaaat catcgcagaa
     1681 ttcgctgatt tatatctaaa agatacaggc gttcttatcg gcacaaattc taaagtatat
     1741 caagaagtga aagaaaaaat cgaagctaaa ctaaatccat caaatcgaaa tcaaccaaag
     1801 aatcatcaaa aaggaacaaa caaaacagtc acttctagca atttcgaccc aactaaattt
     1861 ctaaaacgat aaaaaacaga taggagttat tcctatctgt tttttatttc ccaatattct
     1921 attttttcat tccaagcagt taacggaagt tttcgatatt tattcgacgt gtttattcac
     1981 gccttcaatc atttctccag tttcagaatc tatccttttt gcatattgcg gccgaaatcc
     2041 gttctggtaa ttagcatcaa acatcatacg gaaaagattg ctgtttgaag ctatgacatc
     2101 aacaacatct ctttgattag tgattccata ctcttgacct ctccagtcaa gaaatgcagc
     2161 taactctttc atattgacta ttccacaatg attaacaaga tcaaacaatt ggtttctcaa
     2221 ctctttcttt tgactctcgt ccaaagttac ataacgatca atatcaaaat cattaatatg
     2281 caagatatct tttttatcgt atacatgttt attcttttct tttgcatctt ttgattcatg
     2341 cgtaagatac tcatacgagc ctttgatatg gtcaattatt tctaagtgag caaccgaatt
     2401 atttcccaat tttctcttga ttttctttct tacgctctcg attgttacag gattgcgagc
     2461 aatataaagg acatgataat gtggctttac ataatgctta ccgtttctga taacatcact
     2521 actagtccaa tcctttttat ttgttttttc gtccatatcg tgtaacggac taaccgccat
     2581 tgatactcct aagctctcaa gctgttctct ccaattctct ggaatagatt cgggatatag
     2641 taaaaaacca aaatgtctag ctttcgttat attcttattc atgatatact tacctcaatt
     2701 gaacactatc agttaagcgg aaacggtgcg ccaacacata tgtttctgct ctttttttgc
     2761 gctcaatttc ctttctctga ttttttcaag tcttctgtta ctagcaattt aacatatgtc
     2821 gacatactca aacttttgtc ttttgctttt tcctcaagtt ttcgcttaat ttcactcggt
     2881 aaaattacta ccagtctttc tgattccgcc atgcctttca gcccctttag ttaattgtta
     2941 atatcatggt aaacttttga caactgtatt gtcaatattt ttttctattt ttcaaaacgg
     3001 cggtcaaaac ggcggtcaaa tggcggtcga aaaaaaaagg ctctatccat tggtacagta
     3061 aggataaagc actttttggc acaaaaattg gcac
//
LOCUS       DACCVH010000151         2998 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.159, whole genome shotgun sequence.
ACCESSION   DACCVH010000151 DACCVH010000000
VERSION     DACCVH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.159"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1097)
                     /locus_tag="IVV98_002834"
     CDS             complement(<1..1097)
                     /locus_tag="IVV98_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7808412.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2603)
                     /locus_tag="IVV98_002835"
     CDS             complement(1227..2603)
                     /locus_tag="IVV98_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808413.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2603..>2998)
                     /locus_tag="IVV98_002836"
     CDS             complement(2603..>2998)
                     /locus_tag="IVV98_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808414.1"
                     /translation="NYNLIDYLSPIENIRLVNKSADESILFELGLDKKQIKRNVMKLS
                     GGQQQRVAIARALVSDAPIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHS
                     KEVADSADIILELSGKKLKKVNKMNLEVE"
BASE COUNT          915 a          568 c          417 g         1098 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acgtactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt ttaaactttt tctagttaca
     2581 taagcaaatg cattttttat cattattcaa cctccaaatt cattttattt acttttttca
     2641 actttttacc acttagttct aaaatgatat ccgcagaatc tgctacttcc ttactatgtg
     2701 ttacaactat tacacattta tttctatctt tagctaatgt ctttaatata ttaattattt
     2761 ctccagcagt aacactgtct agattaccag taggctcatc agctagtatt attggagcat
     2821 ctgataccaa tgctctagca atagctactc tttgttgctg tccaccagat aatttcataa
     2881 catttctttt tatttgtttt ttatctaaac ctagttcaaa caagatactt tcatctgctg
     2941 atttatttac taatctaata ttttcaattg gtgataaata atctattaaa ttatagtt
//
LOCUS       DACCVH010000152         2874 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.160, whole genome shotgun sequence.
ACCESSION   DACCVH010000152 DACCVH010000000
VERSION     DACCVH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.160"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            44..1522
                     /locus_tag="IVV98_002837"
     CDS             44..1522
                     /locus_tag="IVV98_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAP7808415.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(1590..2681)
                     /locus_tag="IVV98_002838"
     CDS             complement(1590..2681)
                     /locus_tag="IVV98_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP7808416.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         1007 a          516 c          455 g          896 t
ORIGIN      
        1 aaaaattgtt tgttattatt agcaacaaaa aaaggagtgc atcatgaaaa agttatctca
       61 aaaacgttta gctcaaatca ttattgattc tagaaaatct ctgaaaatga cacaacaaca
      121 acttgcagta gctactggta tcaaccgtgc cttaattagt cgattagaat ctctcgattt
      181 tatcccgtca atacaacaat tagaatcatt agcagaagtt ctaaattttg aaccaacaga
      241 tctatttata aatgaatcaa ataaatcaaa cagaacaaaa catcagtcga agaatattgc
      301 tgtagccggt actggttacg taggtctttc cattgctact cttcttgccc agcacaatca
      361 ggtaacagca gtagacattc ttcctgaaaa agtaaaacaa attaacaata agaaatctcc
      421 aatacaagac gattacattg aaaaatatct agctgaaaaa aatcttaatt taattgcaac
      481 gactgatggt gcagccgcct atagagaagc cgattttgtt gtcattgctg ctccaacaaa
      541 ttatgatagt aaacaaaatt attttgatac ttctgctgta gagtcagtaa tcaaattggt
      601 gttagaagtc aatccaaagg caataatggt catcaagtcg acggtacccg taggctatac
      661 cgaaagtatt cgtaaaaaat acaatactaa aaatattcta ttcagcccag aatttctcag
      721 agaatctaag gcattatatg acaatctata tccttcgcga attattgtcg gcacggacca
      781 aactgacaaa actttacgag aagcctctca cacttttgca gatttactcc aagaaggagc
      841 aatcaaaaaa gatatcgaaa ctcttttcat gggattcaca gaagctgaag cagttaaatt
      901 attcgctaat acttaccttg cacttcgagt atcttacttc aatgagctgg atacttatgc
      961 agaaatgaaa ggactaaata cacaagaaat cattcacggg gtttgcttag atccaagaat
     1021 tggcacacat tataataatc catcttttgg atatggaggc tattgtttac cgaaagatac
     1081 aaaacaactt ctcactaact ataacgatgt tcctcagaat atgataagtg caattgtcga
     1141 tagtaatcgt acaagaaaag actttatagc agatcgagtg ttagaacttg ctggcacgta
     1201 tgaggctaac agttcgtgga atgcagaaaa agaaaaagag gtagtcatag gtgtataccg
     1261 tcttacaatg aagagtaatt cagacaactt ccgtcagtca tctattcaag gagttatgaa
     1321 gcgaattaaa gcaaaggggg caactattgt aatttatgaa ccaacacttg aaaataacac
     1381 tacatttttt ggttcaaaag taataaataa tttagatgat tttaaaaata tcagtcacag
     1441 tattattgct aatcgttacg atagtaatct tgatgatgta aaagaaaaag tatataccag
     1501 agatttattt caacgagatt aaaaaataac acctcagatt tgtagtgtct gaggtgtttc
     1561 tataaacttt tataagtaaa aaaatacaat tatacttcat aaaaagactt ataccactgc
     1621 gcaaatttac gaagcccgtc acgcaaactt gtacttggtt taaattcaaa atctcgttct
     1681 aacgcactag tatctgcata agtaactggc acatctcctg gttgcattgg aactagttcg
     1741 gtatgagatt caaagtcgta atcttctggt agcacccctg ctgcaattag ctcttgttgt
     1801 agaatatcta caaaatctag taggttttcc ggcgtattgt taccaatatt ataaatatga
     1861 tatggtggga ttggtagccc atcttcccca tcaattttct ctggagcgca ctgcataacc
     1921 ctctttactc cttcaacaat atcatctata taggtaaagt cacgcttgca attcccataa
     1981 ttgaatattt ggatattatc accagcacga agtttatcag taaaaccaaa ataagccata
     2041 tctggacgcc cagcaggacc atatactgta aagaaacgta accctgtaga cggaatattg
     2101 taaagtttag aatatgcatg tgccattgat tcattacttt tcttagttgc tgcatacaac
     2161 gatacttgat tgtctacttt atcctctgta gaataaggaa ttttcttatt agtaccataa
     2221 acggaagacg atgaggcata cactaaatgt tccacaccag attctccatt atcatatgaa
     2281 tgacgacaag cttcaagaat attatagaat cctattatgt tagattcgat atacatatct
     2341 ggattagtaa ttgaataacg gactcctgcc tgagctgcta aattcaccac gatacttggt
     2401 ttataattat caaagatgaa atcaattgtt gctttatcag caatagaacc tttgataaaa
     2461 ttccaagtag atcctggatg gttctttgcc tccgtttcta tctctgataa tctatagttc
     2521 ttaatagaga catcatagta atcattcata ttgtcaatgc caatgatttt tattgatgac
     2581 tgagtacgta ataactcaag aaccaaattt gatccaataa aaccggctgc gccagttatt
     2641 aatattgttc tatttgataa ggacgtgttt aattccagca ttttttagca ctcactttct
     2701 ttttttctta tgaatacata tttgttatat attaaaaaat cttatttaga cttatctatt
     2761 gtcactttta tcattctaat ctttgcacgt agtagaataa ttatacagat aggaaattgc
     2821 taagcaaccc acttctttct attatctatt aacttattct aaaacgaata gaaa
//
LOCUS       DACCVH010000153         2822 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.161, whole genome shotgun sequence.
ACCESSION   DACCVH010000153 DACCVH010000000
VERSION     DACCVH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.161"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            46..276
                     /locus_tag="IVV98_002839"
     CDS             46..276
                     /locus_tag="IVV98_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808417.1"
                     /translation="MGFRTKRSLSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDV
                     STSNSISIIGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(367..732)
                     /locus_tag="IVV98_002840"
     CDS             complement(367..732)
                     /locus_tag="IVV98_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808418.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            940..1422
                     /locus_tag="IVV98_002841"
     CDS             940..1422
                     /locus_tag="IVV98_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808419.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1619..2509
                     /gene="pstS"
                     /locus_tag="IVV98_002842"
     CDS             1619..2509
                     /gene="pstS"
                     /locus_tag="IVV98_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP7808420.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          961 a          449 c          551 g          861 t
ORIGIN      
        1 ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg ttttagaact
       61 aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt ttatggagga
      121 attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat agatgtttcc
      181 acctcaaatt caatatctat tattggaatc attattgctg caattattac acaactgttt
      241 ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata gttttggtga
      301 tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta catatatggt
      361 ttgtttttat ggatgccgag cttttttata agataaggct accgcccata acgacccaag
      421 gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg gttttaaagg
      481 atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag tgacagtaga
      541 tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat aatatccagc
      601 aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac gaaaatcaag
      661 cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt ttttccagca
      721 agtttttatc atctttcatc accacctaac aagtgttatt attttgttag ttttattgta
      781 aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat gaataaactc
      841 tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat agaaaattgt
      901 atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa agcagtaatc
      961 gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt tacatgggta
     1021 aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg atttgtggtt
     1081 tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg tctcttatta
     1141 ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg cttattagta
     1201 tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg tttgagcgag
     1261 agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa accatggttc
     1321 tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac agaaatcagg
     1381 ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat catcagtaaa
     1441 aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt attatgtaaa
     1501 gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta cagcaaccat
     1561 acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga gcaataaaat
     1621 gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat gcggctcagg
     1681 atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa atgaacaagt
     1741 aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag cacaagaaag
     1801 ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa gcggaactgg
     1861 tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat ttgcagaaga
     1921 aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg tcgggatggc
     1981 accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat tgattgatat
     2041 ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa aaatcaacgt
     2101 cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg gactggatgg
     2161 tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc agctggtaag
     2221 tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt ccacacaagc
     2281 actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca gctggggaat
     2341 ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc aaaaattctt
     2401 agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg gctatttacc
     2461 aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac tagcagataa
     2521 acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc acatatacat
     2581 ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag ctaataccga
     2641 gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag aactgtcgta
     2701 actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata aaacttagac
     2761 cgatatgcgg cgcgttctgt gcgccgcata tttttttagt tttcaaagat cagaccttgt
     2821 tg
//
LOCUS       DACCVH010000154         2732 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.163, whole genome shotgun sequence.
ACCESSION   DACCVH010000154 DACCVH010000000
VERSION     DACCVH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.163"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(77..1876)
                     /locus_tag="IVV98_002843"
     CDS             complement(77..1876)
                     /locus_tag="IVV98_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP7808421.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2000..2596)
                     /locus_tag="IVV98_002844"
     CDS             complement(2000..2596)
                     /locus_tag="IVV98_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7808422.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          965 a          516 c          478 g          773 t
ORIGIN      
        1 aaaaaacgca tatacctgcg gtggcaggtt atgcgttttt tgttgtataa agactttttt
       61 cattaacgat ttttgattag ccgactccca aaacaaaatt tagcagttta tctgaataag
      121 tgatttcttc atctgtttgt ttcacacttt catttagtag tcccatctca tcggttatga
      181 taccatccac accataaaac atcatgcgac tcatagcatc tgaatcgttg attgtccata
      241 catatacttc ttttccgtct tggtgggcag aattaatgaa gttacggttg atcgtactat
      301 attccattgt cagaaaatca gcaggcgtca cagggggccc aacaatattg aaaggtaaga
      361 tgtagcccac ataaaagttt ggttctgctt cttttaaatc tgaaacggtt tggtacgtca
      421 aactttgcaa aatatgatgg ttctctaaga taactttgcg gtatttatgg acaaatcgtt
      481 cgacaaggtc atccgaatct tttttagagg tcttgatctc aataagtaat ttttggttta
      541 gcttatgtgc tttttccaaa taagaatcaa aagaacaaac aggggcttgc actccgtttt
      601 cagtaactgt aagatttgtc aattctttca atgtaagatc ctgtggtgtt ccatttaccc
      661 ctgttaagtg acgaagattt gcatcatgca tcactacgaa atgaccatct tttgtttcct
      721 gaacatccat ctctacataa tcaggatgat agtctctgct tgttttttca agtgcttcta
      781 aagtattttg cgccccattt tgggtactca cacctctgtg agagacagtc actggttttg
      841 tctgaacagc tgaagtcaga taatccatat tgtaaagaca gacgccaata ccgaaaaaaa
      901 ctgcaaaaag agtcaaacca gtgtttttca gcgcagagaa acgcaagttg ggggcttgtg
      961 ggataaacca cttagggatc tcaggcaaga agccttcgtc atccatgaaa tcaacaatga
     1021 tataaaaaat ccctacggta gacatcacga tattgaataa taaaatccct tgtaaaagcg
     1081 tcatagcaaa cacagcgctg atcaatgcat agtctgggaa aaattgttca accatacttt
     1141 gtgccaaaat aacaacgata tatcctaaag aagaaaggag taaaatcgta ccgccaatca
     1201 caataaattg gcccgtgatg gccaaaagac gcgatttggt caatgaccag ctttcccgaa
     1261 tggctgctcg aaaaggacga tctcgtagaa tcatttccgg taaagcaaaa atcagtcgaa
     1321 tcccaatata gccaaggaaa atataaacga gtaaaaagga actgacgatg atccaacgat
     1381 tagcaaaaat aaaatccata atgaaagcgg ggatttttat ttttgacagt agatcagaat
     1441 taaaacttaa tccgctgatc ggtagaatca ataaaaaata agcaaggaaa aacaaaaaag
     1501 taatgggtct cactttcttc agctgaagta tcgtcaagtg taagagttgc ttcaaagaga
     1561 ttggttcttt ctttttaata aaaaaaacac tcatcaaaag aaaagtaaat tcgaaataaa
     1621 ctaacagtaa aatcgtcatc aaaactacga ttaacgagag tagaacccca ggatgttgag
     1681 aaaaaattga aggaatattg tcataagaca aatagtcaat tgcccctcgg tgtaaaataa
     1741 aacgggtcgt actgctcaat aagggtaaac aaataaataa aataaagcca tgcatcagca
     1801 agacatcacg gaaataagct tgtgttcctt ttaaaaagtc ccaagcatta cctaagctac
     1861 gtttcaaata attcatccta tcacctgctc ttcacattgt agcgcaaatc taatgaaaaa
     1921 ggaaagggtg cagtgtgttt tgcagaccct ttcccagatt taacattgtc aatcaatgac
     1981 taattttaca aaataaatat tatccaagaa gaccacttag atattgacct ccataaatca
     2041 aggccatact atataagaaa atcgacagtg gtttagcaat caaaatgatt agtgtatatc
     2101 gtttcactga catgtttgtc aatccagcca tcaaacataa cgcatcgtca ggagcaactg
     2161 gaagaaaaat agctagagca aacagcttct caaaacggtt ttgattatcc agccagccaa
     2221 tatatttgtt atatgtctta tcgctaatca tggaaagtat gaatggcttt ccataacgac
     2281 gccctagcag aaaaatgata atcgaaccaa tgcagattcc aatatagtta tagataaatc
     2341 cagcataagg gccaaatatc aggacaccag ctgcagtact gatccctcca ggaatgattg
     2401 gaataactac ttgcaggatt tggatgaaga caaaaataat cggtcctaaa atgatggaat
     2461 cacctactaa tcctcttaac gcattcaaat ctttgaaaac acctaaatta ataaaataaa
     2521 tcgtcagcgc gattgatagg cctaatccga taatggatat gaaatttatc agttttcgag
     2581 aggcagcaat attcattatt catcaactcc ttagaggttc tttgttaact atactttact
     2641 agaaaagcaa ctaactgcgc cattttttga tatgacagaa aacaaacaat tttgtaagtt
     2701 catcataagt ataaaagatt gatctcaaaa aa
//
LOCUS       DACCVH010000155         2666 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.164, whole genome shotgun sequence.
ACCESSION   DACCVH010000155 DACCVH010000000
VERSION     DACCVH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.164"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(137..427)
                     /locus_tag="IVV98_002845"
     CDS             complement(137..427)
                     /locus_tag="IVV98_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808423.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="IVV98_002846"
     CDS             complement(545..805)
                     /locus_tag="IVV98_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808424.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="IVV98_002847"
     CDS             complement(942..1355)
                     /locus_tag="IVV98_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAP7808425.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="IVV98_002848"
     CDS             complement(1811..2296)
                     /locus_tag="IVV98_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808426.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="IVV98_002849"
     CDS             complement(2435..2650)
                     /locus_tag="IVV98_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAP7808427.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
BASE COUNT          983 a          444 c          409 g          830 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttct
//
LOCUS       DACCVH010000156         2624 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.165, whole genome shotgun sequence.
ACCESSION   DACCVH010000156 DACCVH010000000
VERSION     DACCVH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.165"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            109..1308
                     /locus_tag="IVV98_002850"
     CDS             109..1308
                     /locus_tag="IVV98_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP7808428.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1335..2603)
                     /locus_tag="IVV98_002851"
     CDS             complement(1335..2603)
                     /locus_tag="IVV98_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP7808429.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT          783 a          566 c          471 g          804 t
ORIGIN      
        1 aaaaaagcat ctttccatgt ggaagatgtt tttttgcttt ttctagttta aataacagct
       61 tttttcatct attttcgtta tactgtataa gaaaaaggag ttgaatttat gaatctaacc
      121 agagatctga tttttttggt tctctatctt attggggtat tctccatcgt ttattggcga
      181 aaacagaaaa aggatccttc cttgttcttt tacagcagta catggacgtt tgcggtaatc
      241 ttgacttatt ttgtcgtgtt ggaaattttt tattcgacct tttatttttt gattccctta
      301 gtgtttttca gtatctttgc cttttcctat ttttcagaaa agcgaaggct gttgaatggt
      361 cttttattca atattttcct cattagtttt ggtatctact tgtttgtctt gctatacgaa
      421 acacaaaata tttttcttgg cggactgatt gccttgatca cgatcccgtt actgcttgtc
      481 tttctattcg gcatttatgg attgatcgtt tttctttttt ggaacggtgt cacagtttta
      541 cgtagagagt cgcattcatt agctaatctt ttaacgttga tactagccat ttttcttaca
      601 ttgtttcttg tttttgactt tttcttgtta aaatatttac cacaatggat aaatgctttg
      661 tttttctgca tcccattgat cttgatctat ctatttatcg tattctacaa ctttttgact
      721 gtctcattct tgtatcagtt caaccgccct cgatacaacc aagacttcat cgttgtgtta
      781 ggcgccgggt tgatcaatgg agaaacagtt tctcctcttc ttgccaagcg aatcaataag
      841 gcgattgctt tttattgggc acaaagccgt gcgacattaa atccgcctat cctattaatg
      901 tcgggtggac agggagcaga cgaaaaagta ccagaagcaa tggcgatgaa acaatatgcc
      961 atggaacaag gaattcctga aagagatatt cttgtcgaaa ccaattcgac aaccactttg
     1021 gagaatatgc gctattcaaa ggaaatcatg gatcagcaaa tgaaaggtcc ctatcgcgcg
     1081 atcttcagtt ccaacaatta ccacattttc agagctggtc tctatgcacg acaagcgaaa
     1141 ctgaaggcaa atggcattgg ggcaaaaaca gctttctatt acttgcctaa cgcgttttta
     1201 agagaataca tcgccatctt gatgatgaac aaaaaaagac atatgatcat ttgcggattg
     1261 cttttcgcag gttccgcatt cttatcactg atcactttac ttttctaaaa aaacaaggtg
     1321 tgacaaaaca tatgtcacac cttgtttttt tctttcattc tcttaactat tggcaaaaag
     1381 agtatccctt ttctgaccgc tacttgctga gcagaataaa taccgctgtt gcctgaacac
     1441 ataaagctga tcaagcagat cataaagaag tatactgccg cttgtgaacc gaacaattcg
     1501 atccccatca caaagcaggc aatcggtgta tttgtcgcac cagaaaatac tccgataaag
     1561 cccaatcctg caagaaaagg aacagaaaca tggagcaaag gcgctagtgc tgcaccaagc
     1621 gttgcaccaa tttcaaacaa tggtgtcact tctccccctt gatatcccgc gcctaaagac
     1681 aaaactgtga agaataactt cccaataaaa tcatagacat gtgcctgtcc attaaatgat
     1741 tcctgcagta atggaagact caatccgaga taacgttgtg tttgcaaaat caatgctgcg
     1801 gctacaacta cagccccacc tatcgtattt cgccaaacag gatgaggaat ccattgtgca
     1861 tatcgcgctt ttaaaaagac gatcgaacgg ctgaataccc aaccaatcaa accaaaagca
     1921 atcccagcaa caaaaacttt gaagaacagc aacatactcc attcaggaat cacacccatt
     1981 tggtaatgta gatgagaaac accatagctt tctgtcataa aatttgcaaa cagtgcagca
     2041 aagaagctag ggaagatcgc ttctgttcgg actttcccga ttgccaacac ttctaatcca
     2101 aataatgttc cagctaaagg tgtgccaaat acagaactaa aacccgcact gattccactg
     2161 ataatcaaga tttcccgttc tgatttatcc aatcggaaca aacgtgctgt attatctgct
     2221 aacgctcccc ccatttggac tgctgttcct tcacggccaa cagatcctcc aaataaatgg
     2281 gtagttatgg ttccaaacag tgtaagtgga ataagtcgca acgggatttt ttcttctcca
     2341 ccatttcctt gatcgatcac taagttgttt ccacgactag aaagaccgcc gtgatacgca
     2401 tagagataag caaaaagcgc accactaact ggtagtagat aaaggagcca aggatgtgat
     2461 agtcggatat ctgtcacaac tgtcaggcta tttaagaaaa aagcagataa gctccccatg
     2521 aatataccga gaatcgctgt gatcaccagc cacttcagca tgtacactaa aatgcgtact
     2581 ggactcggta attgtttttc cataaaaaat tcctcctcaa taaa
//
LOCUS       DACCVH010000157         2523 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.166, whole genome shotgun sequence.
ACCESSION   DACCVH010000157 DACCVH010000000
VERSION     DACCVH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.166"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(966..1484)
                     /locus_tag="IVV98_002852"
     CDS             complement(966..1484)
                     /locus_tag="IVV98_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAP7808430.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT          822 a          457 c          361 g          883 t
ORIGIN      
        1 ttttacttgg tatatttatg aataatcgca aatttacccc tatactacta gtttgtaagt
       61 tagattaata aaaatactaa agttatttgt tcttttatta aatacaccta caacttataa
      121 attgatggta tttagataac acgaaagaat aaaaataaca gctgatagta aagtttgttg
      181 acgattgcta ctcaatcgaa agtgagttag tgcgtatgaa cttgcttctg aaaacttatg
      241 aaatgaaaga ccttttacat cttgcagaaa tcgttactgg gattaaacta agcaataaaa
      301 actaatgttc ccctcattct ttgaacttct actatttgat ttatttattc tgataaatga
      361 cgatttcacc ttcaggatct tcaaatcccg tatagaattt atttaagatc tcttcagtat
      421 cagtaatagg ataggcgata ggccacatac cctttgatgg ttagaataaa ctgctcaaaa
      481 tctgtatcgt atgttggctt tagcatatta acaaaggcta tctccaaatt ataaaccata
      541 agcgttgaat cgttcttaac aatttcaatt cttcctaacc caaagtcaga agatataatt
      601 accggacttg ccttaccctt catgtgggtt gttgagattc catatttaaa gggaattgtc
      661 ggtactatcg gcggtctgaa aaacatccca aaaataaaaa aatctttccc ctgctagtct
      721 cctaagtccc tttgtagcgg atatggcacc ataatctcat tttatcgaag tgagtcatgg
      781 tttatctgtt ggccaaccaa aattgataca atctaacgat gcaccctcta cggcattcta
      841 ggggagtgca cttgcattca cccaataaaa accggcagtt agcaaagaac ttatgtagtc
      901 gtatgttctt actgttaaca tacaagaggt ctcctttcca caattgctta gcagtaaacg
      961 ggaatttaca aagctaatct cttccatttt cttatctttg ttctaaaagt cccaaatgga
     1021 gcaactgtat ttacatgaat aaatttatat acttcccata cagccgtttt ggttgcctcg
     1081 tctgcccatt ttcttttgtg tgcagtgaat agatcttcat cactcattga atcaatcatc
     1141 atgttaatat catcaatatt acgattgaga atttcctcta attctttcaa tggtagatgt
     1201 gcataggtat ttgtaaacca cttatataac tctcctaact gattccattt aaattgatca
     1261 gaaggcgttt taacagataa tccatttctt tcatcatttt cccattttag aattaaattc
     1321 gtccaaccaa cttgatatgc taaattttca gcaggtgttc tatccacttc ctcaactctt
     1381 ttatccttca attcttcagg aatagtttca aattctaaaa tatatttagt ataagtccta
     1441 tttatttctt tttttaattc ttctttattt ttatatgttc tcattatatt acctccataa
     1501 attcctaatt gtctccttta attcatctat aatttcatcc acgatatttt aatccgttct
     1561 acaatgcata tctgatatgc attgactgtc taactcatat gtgaatgatt tataaaatat
     1621 cccaacgtct catctaaaga aatgttgatc gtcagcaagg agctaaaaaa tacgaatata
     1681 tttcttttgt agtaaaatcg gactggtttg catatcattt tcttcgtaaa tatcaaaatc
     1741 atgttaacta ctatcaatta ctaataaaaa ctaccacttt aagcgttaag aactgttaag
     1801 tttagttaag tgaggatagt tcacaaaatc cattgttaaa cttcacgaaa gtggtaaaac
     1861 tcaaaatgct ttatatagga ttacagcatc gctctttctt cgattgcgcg ttgggtaaaa
     1921 aatattatga agtaaaaatt gacgatgaca cgttccttac ggctcatcag atgaaacagc
     1981 tacaaaaacg aaatgatcaa ctcgaagaaa atttaattct aaaaaagcga ttgccatatt
     2041 cacgcctcgc tcgacgaact attaaaggtc aagatttacc tgaagatcat cctttttagg
     2101 aaattgaagc tttttatgtt gcacaatgca tttataatac tacaatgatg ttttcaccag
     2161 atattcttct agggtgcggt gtaatgaaac agatacactt gcaaaagaaa attcaccgcg
     2221 aatttactaa aattatgaat aattatgtta atcttccgaa atttttttcc aaaattaagg
     2281 gatcaagctg gtgttataga ttgtttaagg ttggcaaaaa aataacttct ttttaaacaa
     2341 ttatagaaaa ccgatactct gttaagttgg ttgacacggt gtcgattttt atgactttct
     2401 tattctgaaa cttcactaac ggacagtacc taaaaagtct atagtatgga cgtttacgag
     2461 tactatttta tcaaaaatgc tgctcatttc aacttatatg ttttagtgaa ctacccccac
     2521 tta
//
LOCUS       DACCVH010000158         2500 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.167, whole genome shotgun sequence.
ACCESSION   DACCVH010000158 DACCVH010000000
VERSION     DACCVH010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.167"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..435
                     /locus_tag="IVV98_002853"
     CDS             <1..435
                     /locus_tag="IVV98_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP7808431.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="IVV98_002854"
     tRNA            complement(759..842)
                     /locus_tag="IVV98_002854"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="IVV98_002855"
     CDS             1370..1870
                     /locus_tag="IVV98_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7808432.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="IVV98_002856"
     CDS             complement(2060..2404)
                     /locus_tag="IVV98_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP7808433.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT          780 a          478 c          413 g          829 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat
//
LOCUS       DACCVH010000159         2464 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.168, whole genome shotgun sequence.
ACCESSION   DACCVH010000159 DACCVH010000000
VERSION     DACCVH010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.168"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            161..2314
                     /locus_tag="IVV98_002857"
     CDS             161..2314
                     /locus_tag="IVV98_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP7808434.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          842 a          428 c          545 g          649 t
ORIGIN      
        1 aatagttgga tatgtaactt taagtgattg ctgtgaaaca aaaagttgat tttatcttga
       61 aattaggtaa agaatttctt gctccgccca ttttttcttt tttattaaga agtttttggg
      121 tacaatgaag catgaatgta aataggcgga aggataggaa atgatgaaag attttatgaa
      181 aaaaatatta aatacttctt ggttagaaaa aataagaaaa ggtgcacaag aacctaagaa
      241 caaaacgttt cgccggtccc atgttccttt tcgcttaaat tttctttttt tcattatatt
      301 tacgttattt gttgcgttga ttgctagatt gggttatttg cagatcgtga acggcgaaga
      361 gatggaggcg cgagtgaagt ctacttctac gattacggtc caagaaagta ctcctcgcgg
      421 aatgatctac gactccacag gaaaagcttt agttacgaat aaagcgaatc aggccatcac
      481 atatacgaga ggaacacaag ttacggctaa agatttgctt gaaatcgcaa cgaagctgaa
      541 ctcgctgatc gatgttccgg tagatgaaaa tctgacagat agagataaaa aagatttttg
      601 gctggctgat cccaaacatt tgaaagaagc cacaaaaaga ctttcggcaa aagaaaagca
      661 attagggaac agcgaacaat atagtgcgat ggtcaataaa gtcacagctg atgagattaa
      721 tttaaacgag gagcaattaa aaattgctac catctttaaa cggatgaata gtgcatatga
      781 attaaacact gtctatatca aaaactctgg tgttactgat caagagttag ctgttgtggc
      841 agaacgcgct tctgaacttc caggagtttc gactggcaca gactggacac gagaatataa
      901 tgcagcaagt tcactgaaaa gtattcttgg cagtgtgacg actgaaaagc aaggacttcc
      961 agcagatgaa gcagagaaat acctagcaaa aggttattct cggaatgacc gtgtaggaca
     1021 aagttatttg gaaaaacaat atgaagatgt cctgcaagga accaaaaccc aatatgaagt
     1081 ttcccttgat aatgaaggaa atgtttcgaa tcaaaaagaa atcttctctg gggaaaaagg
     1141 ttctaattta atgttatcta tgaatgcaga attccaatca aaagtagaag aaattttgaa
     1201 aaggaattat caaacattga tcaacaacgg caaagcacag tattcgcctg gtgcttatgc
     1261 agtggctatg aatcctcaga caggagaagt gctagcaatg actggtttca gtcatgaaca
     1321 aggttccaaa gaaatcaccg agaatgcttt aggcacgatt actagcgcct ttgatccagg
     1381 gtctgtagtc aaggctggta ctttgacagc aggctgggca agtaacgcga tcagcggaaa
     1441 tcaagttttg attgatgagc cgattcgtct gcaaggtgct tcagaaaaaa gctctgtctt
     1501 taatcgaagc ggacaagttg ctcttgatgc agtcaaagca tcggaattgt cttctaatac
     1561 gtatatgatc aaagtggcgt taaagatgtt aggactagac tatacacctg gaatgggact
     1621 acctagttta gatgaagaag ctaaagctta tcagcaattg agagactctt tcaaagagtt
     1681 tggtcttggt acaacgactg ggatcgattt gccgaatgaa tctcctggga tctcacgttc
     1741 tgttgattat atgaagaagt tcaatgcgga taatggcaaa gaatggtatg ctccaggtaa
     1801 ctttaccgat ttggcatttg gacagtttga cacatataca ccaatccaat tagctcaata
     1861 tgcttcaaca gtcgctaatg gcgggaaacg agtacagccg cacctagtca aagcgatcta
     1921 tggcaatgac gaaaatggaa acttgggtga agtgaagaaa gaaattggca caacagtaga
     1981 aaatacggtc aatatttctg cagaaaatat ggcgatcctc cgtgaaggat tccaccaagt
     2041 tgtccatggt accgatcctt acacaacagc caaaccatta gccagtgcga aaatggacct
     2101 ttccgcaaaa acagggactg cagaaacggt tgcggaaggt catccagata ttgcgacagt
     2161 caatagtaat atcgtggcat acggaccaac agacaatccg gaaattgcca tcagtgttgt
     2221 cttgccgaac ttattagacg aacaagacca cataaacttg acgattgcta aagaaataat
     2281 ggacgcgtat tatgatatgt tcatggcaaa ataaaaaaga ggtcgtgaaa aagccgctta
     2341 gtttcgagta tgaagaaaaa ttttgtgaaa atagcttctc acatttttgc ttaaatttga
     2401 cttcataccg agaaactggc ttttgaacac cgtttactcg gcaaaaaagg ttgtgacaaa
     2461 aatt
//
LOCUS       DACCVH010000160         2398 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.169, whole genome shotgun sequence.
ACCESSION   DACCVH010000160 DACCVH010000000
VERSION     DACCVH010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.169"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            207..2069
                     /locus_tag="IVV98_002858"
     CDS             207..2069
                     /locus_tag="IVV98_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7808435.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="IVV98_002859"
     CDS             2069..>2398
                     /locus_tag="IVV98_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7808436.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DACCVH010000161         2380 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.170, whole genome shotgun sequence.
ACCESSION   DACCVH010000161 DACCVH010000000
VERSION     DACCVH010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.170"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            141..1100
                     /locus_tag="IVV98_002860"
     CDS             141..1100
                     /locus_tag="IVV98_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7808437.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            1964..2176
                     /locus_tag="IVV98_002861"
     CDS             1964..2176
                     /locus_tag="IVV98_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808438.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          860 a          380 c          410 g          730 t
ORIGIN      
        1 acattttcct ctaggaaaaa attaactagc accacgggtt tttattacgc cgattgtaaa
       61 attaagctag acaactaaaa aagtcatttg tgctacactc aaaatagttc cgaccaaaga
      121 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaataa
      181 tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc ttgaatcgtt
      241 caagacaaac gatccataaa gtatatctgt tcttcaagca aggaaaatca gccttagaat
      301 attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt gttttacccg
      361 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      421 ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt atgttcaaaa
      481 aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg aatggacatc
      541 aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa aaggattata
      601 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ctgaaacata
      661 aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca ttgaaaccgt
      721 gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa tctgtaccga
      781 aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      841 tcagtaatgt caatgatatt gccatttatt tcgctgatcc aggaacgccg tctcaaagag
      901 gcctaaacga gaattctaac ggattgttac gtagagatgg tttattgaaa tctatggatt
      961 tcaattcagt agatgaattt tttattcaat ctgccgcatc taaacgaaat aatattccta
     1021 gaaaatcact ggattatcga acacctttgg aagtattttt gagttacgta agtattgatg
     1081 atctgtctaa cttaatttga caattaagat tatattaaat attatacaga taataacgga
     1141 atattatcat cgaaacagct aacaaaattg tcataaaaaa cgagatggtt gatattagaa
     1201 cttgtgtttt tgtttaggtc tagagataaa gagagacaat ttccaaatat atgtaatgaa
     1261 tacaaaaaga cgtttgtcgc ggattaccgt tacaaacgtc ttttattgat tttccgagat
     1321 ctcatcagtc gccatttgga atggttcact ccttatctag attcgtttaa tgctcggact
     1381 gcttgttcga ttgtaatacc aaacgcaacg ttattttcgt tttgtgcatc aatcgccata
     1441 aaacggttag aagttgtatc aaaagctacg cggtattgca tatttgtttt tgtaaacgtc
     1501 ataaaattca tctcctttgt aatgtaattt agttcttgaa agtttccttt aaactttcga
     1561 acttatacca agtttagcat cgtacgtttt ttgatgcaat taaaaagcat ttatcatttt
     1621 ccttatttat tttttcttaa atggtttagc tattttcttt taatccgata agtagcccaa
     1681 tcatcaaggt tacaaatact attgcttgaa tataaatcat atgctcacct ctttataaat
     1741 aacttagcaa tataaagaaa aaaacgcacg aacaacatag gaatataaac aaacgttttt
     1801 gtcacaacgt ctaagatcgt gttaaaaaat agttatctaa aaagcagaaa gatactcaaa
     1861 ataaaaaata aaaaaatgga taaaaacgtt ttcaaataca aggtaatttg ttattataaa
     1921 ataaagaaaa aacaaaataa aaataaagaa aagagggaat gaaatggtaa aagcagaagt
     1981 aggaagatct tatatatgca aaccgatcgg agtatctcat gaactaatcg gctgtattga
     2041 acgtacatat atcaacacgg ctgtcgtgta tgttgaaagt tatgaccaac gagactatca
     2101 acttatcaat gaaagcaagt atcgcatgct cgtaaaattc tgtgatatta gcgcacctgc
     2161 tgaattggtt tcttaaacag tatttttgag aattcgcaag aactccctta taatataaat
     2221 aaagacagaa gggagcgaga agatatgcca aaaagaaaaa gttcagggaa aatgggaatt
     2281 attcttgcag tgatctctgc aattcctgct attttagcta ttgttcgtgc gatgaaggaa
     2341 tcaagagaaa gttaagcaca cattatgagc gtcaaacaaa
//
LOCUS       DACCVH010000162         2293 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.171, whole genome shotgun sequence.
ACCESSION   DACCVH010000162 DACCVH010000000
VERSION     DACCVH010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.171"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(51..1598)
                     /locus_tag="IVV98_002862"
     CDS             complement(51..1598)
                     /locus_tag="IVV98_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP7808439.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="IVV98_002863"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="IVV98_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP7808440.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="IVV98_002864"
     CDS             complement(2043..2237)
                     /locus_tag="IVV98_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808441.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DACCVH010000163         2270 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.172, whole genome shotgun sequence.
ACCESSION   DACCVH010000163 DACCVH010000000
VERSION     DACCVH010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.172"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            191..445
                     /locus_tag="IVV98_002865"
     CDS             191..445
                     /locus_tag="IVV98_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7808442.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="IVV98_002866"
     CDS             446..763
                     /locus_tag="IVV98_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7808443.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="IVV98_002867"
     CDS             1322..2257
                     /locus_tag="IVV98_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808444.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DACCVH010000164         1936 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.173, whole genome shotgun sequence.
ACCESSION   DACCVH010000164 DACCVH010000000
VERSION     DACCVH010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.173"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            84..1550
                     /locus_tag="IVV98_002868"
     CDS             84..1550
                     /locus_tag="IVV98_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7808445.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT          596 a          331 c          397 g          612 t
ORIGIN      
        1 aaataacact gtcttgtaag tttgttaaaa attgaatatg attacatctg gataacaaat
       61 ttttatcata aaggagagaa cgaatgaaca acaaacaatt acgctggttt actgttgcgt
      121 taattgcatt taacatggtt tggggcatgg ggaatgtagt taataactat gctcagcaag
      181 gagtatcagt tgtcacctct tggctattga ttttggccat ttattttatt ccatacgcat
      241 tgatcgttgg acaattagga tcagccttca aggatagtaa aggaggcgtc agttcatggg
      301 tcgaaaatac gacatctaat aaacgactgg catactatgc cgcttggact tactgggtcg
      361 tccatattcc ttatttggca caaaagcctc aagcaattct gattgctggt ggttgggcag
      421 tccaaggaaa tggaaatatc gtaaatacga tgtcagtaca aatggtagca gttatttcac
      481 ttattatatt tcttgccttt ttatatttat caacaaaagg actttctact ttgaaagtga
      541 ttggcggact ggccggaaca gcgatgttcg tcatgtcgat cttatttatt cttttagctg
      601 taacggcacc gttcatcaat ccaacgatgg aatttgccac accacatatg aatcaagtga
      661 aaacatatat tccaacattt gatttcagtt atttcacaac cgtttcgatg ctagtatttg
      721 cagttggagg ggcggaaaaa atatcccctt atgtcaactc tacaagaaat cctgcaaagg
      781 aatttcctaa agggatgatc ttcttagcag caatggtagg gatttgtgct gtattaggct
      841 cagtcgcaat gggtatgctg tttgctagtg ataatattcc taaagacttg atggcaaatg
      901 gggcatacag tgcttttcaa attttaggta attactatgg tatcggtaac tcattgatga
      961 tcatttacgc attgacaaac atgattggac aaatctccgc attagccttt tcaattgatg
     1021 caccactaaa aatcttgtta gcagatgcgg atccagaatt tgtaccaaac tggctacgta
     1081 aacgtaatcg taaaggtaca ttggtgaatg gttatcttct gacaggtata ctagtaggaa
     1141 tcattatttt gttgccgatt tttggtatca aagatatgaa tgaattagta aaatggttga
     1201 cgaacttgaa ctcagttgtc atgccaatgc gttacctatg ggtgttcttg gcatatatga
     1261 tgttgaataa agcttataag aaattcaatt ctgaatataa atttgttaaa aatccaaaaa
     1321 tcggttttat ctttggtgct tggtgctttg ccttcactgc gtttgcatgt atcctaggaa
     1381 tggtgccaaa agtagattat actgctgatc ctaaagcatg gtggttccaa ttatttacga
     1441 atatcatcac accaatcgtc ttgatcttat taggtatgat cttgccagca attgctcgtc
     1501 gagacaaaaa caaagaaatc actgaaccag aaacagtggt tcagccttaa aatagaaata
     1561 cttgttacaa gaggttgtga cagaagtggt cagcttcaag aaataagaag gaatttacga
     1621 aaattgcttc tcaaattttt gtgaagtttc ggcttgtttt tcgaagaagc tacttctgga
     1681 acaccgtgaa tcagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
     1741 caaaaatagc ccctcatatt tttcgtttgg ctgggcttat taccgcagat gcaagctttg
     1801 gaacaccgtt taaggaagag gttgtaaaat cagcgatttg acctgagtat tagagaaaca
     1861 aacggaaaaa tagctcctca tattttgccg ctttttgagc taatgctgaa ggtcagctga
     1921 ttgaacacca tttatt
//
LOCUS       DACCVH010000165         1879 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.174, whole genome shotgun sequence.
ACCESSION   DACCVH010000165 DACCVH010000000
VERSION     DACCVH010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.174"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(30..572)
                     /locus_tag="IVV98_002869"
     CDS             complement(30..572)
                     /locus_tag="IVV98_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP7808446.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            707..1096
                     /locus_tag="IVV98_002870"
     CDS             707..1096
                     /locus_tag="IVV98_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808447.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1100..1864
                     /locus_tag="IVV98_002871"
     CDS             1100..1864
                     /locus_tag="IVV98_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7808448.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
BASE COUNT          583 a          335 c          371 g          590 t
ORIGIN      
        1 agatattaga cagtttttaa gtttgtgagt tattttcctt gtcgttttct cactttttta
       61 gtccagaaac cacctgaaat atattttggc tcataagaaa tgataaaagc acgctcttcg
      121 atttctttga tcaggcgata cagttcacgt tcgctttttc taggagaaag tatttcgaga
      181 actagccgct caccttccag ccccattgca gaagtctgtg tcacaccata accgtgttct
      241 ctcagtatac ccggcaaact tttatcttct gcgctatttg ctggcaaaat cgttgtgacc
      301 atgatgtatc ctaatgccaa tttgtcttca atcaaaattc cgacactgat acctactgcg
      361 taacctaacg catagacaaa taaattcagt ggattatcta aacgatctaa aacaagggat
      421 aagccgacga tataaatcgt gatctcgacc atactgacaa gtggagcaat cagtcgatag
      481 cctttcattg tcaacatgaa acgtaacgtg ttcagagtga tataagcaaa attaatgagg
      541 aagatcatcc ccaacatttt tggatcaatc atttgtaaaa ctcctttcat ttatataaca
      601 acaatatcaa aaaaaatcgt aagtgaagaa aaattgaaac tttatacata caaaaaaatg
      661 ataaaatgat tataatagaa ttataaagat aggttaggtg attaaaatga aaacggtcaa
      721 tcgtgtgttt tgtgccagcc acgtgctaag tctccttctc agtatatact taggtgtcta
      781 ttcgattcaa cagccaattg aggtagagaa cattgttttt cagatgtcgc tgacagatgg
      841 tttaatttta agcgtttttt tctttttgat actgtttatt ggtaatattt tcggtagcgt
      901 tgccagtttt ttgaattttt ctatttatcc actcctttcg ctagcattag gagtggtggg
      961 actttgttct ctgtgcttat ttcccgagcc attcagtcct gcatttatat tatttggtac
     1021 actgaacctg ttccagacaa ctgttggagc atggttgcta tggcgatcag gaaatttaat
     1081 gaaaataggt gagtaacaat tgaatccaat tatattgaaa cgttctgtcc atcatattcc
     1141 agtgttagaa gttgttctga aagaattaag agaggaacgt attcccgttg tcatctatta
     1201 tcacggatgg cagacaagta aggagttagt tttgacgcaa ggaagaaaaa ttgcgcagca
     1261 gggcattcgt gtgatcctgc cagatgcgat gaatcatggg gagcgcaaac agccggtttc
     1321 ttctattcca tcctatacat tttgggatag tatctacgga aatctgtttg aatttgacac
     1381 acttatcaag catttagaaa aaagaggtct tctacatgat cagcttgcag ttggcggggt
     1441 ttcgatgggg ggaatgacaa catgcgcctt gttggctaaa catcctcata tagtagcggg
     1501 cgtgtgtttg atgggttccc ctgcaccttt ggaatatgga aaagaaatcg taaggcgcgc
     1561 atcggaatat aattatgtcg taccaaaaga ctattttgat ttgatttcat gggttaagag
     1621 ctatgatttg tcattgcagc cggaaaagtt agctggacgt cctctgttct tttggcatgg
     1681 acaagctgac gaaaaaatcc cttatataca aacggaacga tttgtagaaa aaaatcggca
     1741 taagtcttac ggaaaagaaa ttgtttttcg ttcctcaaaa acacagcgac atatggtaca
     1801 aatacaacta atggaagaag cttccacttt tttagcaaaa aatttgataa aaaagtataa
     1861 ataattgaaa cggaaaatc
//
LOCUS       DACCVH010000166         1872 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.175, whole genome shotgun sequence.
ACCESSION   DACCVH010000166 DACCVH010000000
VERSION     DACCVH010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.175"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..510
                     /locus_tag="IVV98_002872"
     CDS             <1..510
                     /locus_tag="IVV98_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808449.1"
                     /translation="KNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSI
                     FSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPS
                     MMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAEL
                     RKLVEYGII"
     gene            497..>1872
                     /locus_tag="IVV98_002873"
     CDS             497..>1872
                     /locus_tag="IVV98_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP7808450.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVI"
BASE COUNT          614 a          240 c          286 g          732 t
ORIGIN      
        1 aaaaacatac aatcaatctt tgggatagaa gaagtttttg tcggagataa atgtatcttt
       61 tttgatcaac ctttattatc tgatggttat ggcatagatg aaacagatat tttcgctaaa
      121 gtaaatagta tattttctgg aaaaaaagaa actttaatta agcttcatcc tagagcaagg
      181 acaaatcgtt atggtgaaaa aaacatattg aattccagtt taccgtttga agtcttgcta
      241 cttgaaaatg acttctcttc aacacttttg attagtccta tatctacaat ttctttttca
      301 ccatctatga tgtttgaaaa gacgatcaac tctattatgt tggctaaatt aattttaaat
      361 gaatatacag cattatctga agataaaaaa gaaacattga caaatattgt tcttttctgt
      421 gaacattata accgtctatc agaagaaaaa attttactcc cagaaaactg ggcagaatta
      481 agaaagttgg tagagtatgg gattatttaa cacactttcc aagtcaaaat tagttaagtc
      541 cagtttctgg tatactatag ggaatttttt tattaaggga atttcattca taactattcc
      601 tatttttgta aatattacta ctcaagcaga atatggtttg attaataatt tcacttcatt
      661 tgtatcaatt ttttcgattc ttgttgggct aagcctaaat tcggcaatta ataatgcaag
      721 ttttgactat aaagatgaca taaatgaatt tatgtcatcg gtactttctc tagctacact
      781 ttcgttaatt gtgttcttat taatagggaa catatatttt ttgttttcaa atgctttttt
      841 tgatatgaac caacttgtat ttaatttgat gttattacaa agttttgcta gttttgtaat
      901 tagttatatc cagtcttatt ttacgattaa ctttaaccat tttaaatatt tgattttatc
      961 ttttatatct acttttttga atattgcaat ctctgtagct ttgatgcaga cattatattt
     1021 tgatgataaa tatgttggca gagtagtcgg cggaacactg tcatttgtgt tgataggttt
     1081 agtaatttat ttaagaataa tgataaaggg tgctcatttt tttgataaaa aacagtggag
     1141 atacgcttta aaaatctctt tgccgctaat cccacattcc ttagcaaata tagttttagc
     1201 acaattcgat agaattatga ttaattctta tttaggtcct gctgcggggg gaatatattc
     1261 ctacattagt aacataggta ttattctaag cgtaatatgg atgtctacta ataacgcctg
     1321 ggttccatgg ttctatggtg agatgagtaa aaataatgaa aaaaaagtga agaaagttag
     1381 taactattat ttagtagtct ttactttgat tacgatgatt gtaatggtag tttcgattga
     1441 tttagcaaaa tttatggctc cgaaagacta ttattctggg ttatctttag tggttccgat
     1501 aaccttaggc tatttctttc agtttttata tagtttacca gttaatgctg aattttatga
     1561 gaaaaaaaca tcgtttattg cgattggtac agtagcaagt gctatagtta atatactatt
     1621 aaacatgatt ttcataccta ggttaggaat aattgctgct ggatacacaa ccgtatttac
     1681 gtatttttta ctttttattt ttcattataa tatcgctaaa aaaattacga ataaacaatt
     1741 atttgacaca aaaaaaatat gtatcataat aatttttgta tcaatttttt ctttgatact
     1801 tcatatttta atcaatcaaa tgttgattcg ttacgttttg acatcattat tgataattag
     1861 tttagttata ta
//
LOCUS       DACCVH010000167         1864 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.176, whole genome shotgun sequence.
ACCESSION   DACCVH010000167 DACCVH010000000
VERSION     DACCVH010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.176"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(308..763)
                     /gene="tnpA"
                     /locus_tag="IVV98_002874"
     CDS             complement(308..763)
                     /gene="tnpA"
                     /locus_tag="IVV98_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP7808451.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1006..1864
                     /locus_tag="IVV98_002875"
                     /pseudo
     CDS             1006..1864
                     /locus_tag="IVV98_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          588 a          361 c          353 g          562 t
ORIGIN      
        1 gtgttcgata atccagtgat tttctaggaa gattatttct gcgccagcat tttctaatgt
       61 ttgaatttgt gttttgtaat cttggttgct tgtgctaatt cttgaatagc cgtaaattgc
      121 caaaatttca tcaccctttc tggacataag tttctgacac cagttaaaat caagtctatc
      181 agtaacccat acacccgtga ggacgggtgt atttttaatc cccctagaag gggtcgacac
      241 tcgctgcccc ttaaaagggg atttttaaaa gaccgccaac tgctcatctt cactcactta
      301 cttctcttta ttttttaaat ggttctacgt actctctttt acttataata tatcgaatgc
      361 gatcatcagc ttcttgttca cggatgtatt tttcatttgt cttttgattc aatccgactg
      421 tactcacata gtatctcttc gaccaaaagg atttgtttcc gtatttatat ttgagatttg
      481 cgtgctgctc gtggattagt accgcactac gacctttcag ataccccata aaactggata
      541 tacatatttt tggtggtact cgaacaagca tgtgaatatg atctagcatt gcatgtgctt
      601 ctatgatttc cacatctttc atttcgcaca acttcctaag tatttttcca agatcttttc
      661 gtaattgccc atagattact tttcgttgat attttggtgt aaaaataata tgatacttac
      721 aattccaacg agtatatgct aaacttttat cgtcatttga catgaaaaaa ctcctttcga
      781 tctgatgagc ggttggtagc cactcactag tatatcgaaa ggagttttta tcgctaaaga
      841 tacttcttcc acgcgtagaa acgcgcggtt ttcttgtttc gcacgcttta cgcacaaaac
      901 tgactgaagt cattaagaaa ataaaagggt ctaaaacttt taagttttgt accgaccccc
      961 aaaagttaga ccaaaaaatc taacttttgg aggtcggtat tttttatggc taagtatact
     1021 tttgaactta aattaaagat cgttcatgat tacttggatg gtaaaggcgg aagtgattat
     1081 ctggcaaaga aatattccat taaggctcca tcacaagtga agcgctggat caatgcctat
     1141 caagaatttg gtgaagaggg tctagtaaga aagcgacaaa agaaaaaata ttctgttcaa
     1201 tttaagctgg atgcgataga gttatatcta acaagtgagc tgtcctatcg tgaagttgcc
     1261 aacacactta acatgaacaa ccctaatttg atcgctagtt ggatgcgtca attccgtgag
     1321 ggtgggatcg atggactctc aaaaacgaaa ggatgtccac ctatcttgtc taagaaaaat
     1381 gaacccaaaa ataagaaaaa atctacaact aaagcaacgt ctaaagaacg tgaacgcatc
     1441 gaggagttgg agaaacgagt ccgttccctt caaattgaaa atgccttttt aaaagaattg
     1501 aggaagctgc gaaaacagga agcccaacaa cgacgaatga agcaatcgca cgaatcatcg
     1561 caagcctccg aggaccgttt aaattagttg agcttctaga aactttaaag ttccctaagg
     1621 caatctttat gtactggcaa aaacgattgg accgtaaaaa tccagatcaa gagattgaag
     1681 cggaaatgct taaagttcgg gagaagcaca aggattatgg ctgtttacgg atgaccaatg
     1741 aactaagaaa ccgcggtttc tctatcaata aaaagaaagt tcagcgcctg atcaagaagc
     1801 taggaataaa agtaacgaca tacacacgta aatcacggcg ctacaattct tatcgaggac
     1861 aagt
//
LOCUS       DACCVH010000168         1859 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.177, whole genome shotgun sequence.
ACCESSION   DACCVH010000168 DACCVH010000000
VERSION     DACCVH010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.177"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="IVV98_002876"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="IVV98_002876"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7808452.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DACCVH010000169         1854 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.178, whole genome shotgun sequence.
ACCESSION   DACCVH010000169 DACCVH010000000
VERSION     DACCVH010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.178"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="IVV98_002877"
     CDS             complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="IVV98_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP7808453.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..1709)
                     /locus_tag="IVV98_002878"
     CDS             complement(1305..1709)
                     /locus_tag="IVV98_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAP7808454.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          551 a          329 c          299 g          675 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaaacttt tagaccagaa catttctttc caaagaaatt gtttgactct tggaaagtca
     1441 cgttttatca atcttgagct ggcactttta taggcattga tgaattttgt caattctgtt
     1501 ttaggttgag ctttgaacat aatatgaacg tggtctttat catgattcca ctccactaaa
     1561 gtaatgtgat acgattctga aattctttca aaagtagttt tggcataatc agatatttca
     1621 tcatcaatca cttgtctacg atatttcgtt actaaaacaa ggtggtaata aagaagaaat
     1681 actgaatgat tatttgtatc taattccatg ttatatcaac tcatttcttg tatagactga
     1741 ttgtaacatg gaacaaaata aaaaggcaat acgccttagt tgtcggtctt cgagttacca
     1801 acggtaaccc tcataccgaa cggcattcat cacccaccta tagaggatgg gcga
//
LOCUS       DACCVH010000170         1850 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.179, whole genome shotgun sequence.
ACCESSION   DACCVH010000170 DACCVH010000000
VERSION     DACCVH010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.179"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            288..695
                     /locus_tag="IVV98_002879"
     CDS             288..695
                     /locus_tag="IVV98_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808455.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="IVV98_002880"
     CDS             709..1110
                     /locus_tag="IVV98_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808456.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="IVV98_002881"
     CDS             1112..1483
                     /locus_tag="IVV98_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808457.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1818)
                     /locus_tag="IVV98_002882"
     CDS             complement(1519..1818)
                     /locus_tag="IVV98_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808458.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          689 a          243 c          311 g          607 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca cccttcttca ttctagtttt cgcagcagga attttgaaat agttcttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
     1801 tgtctcatta aaaagcataa ccattactcc gatctgtttt taaaattagt
//
LOCUS       DACCVH010000171         1847 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.180, whole genome shotgun sequence.
ACCESSION   DACCVH010000171 DACCVH010000000
VERSION     DACCVH010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.180"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            700..>1847
                     /gene="ltrA"
                     /locus_tag="IVV98_002883"
     CDS             700..>1847
                     /gene="ltrA"
                     /locus_tag="IVV98_002883"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004853597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7808459.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
BASE COUNT          730 a          281 c          384 g          452 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaaga
//
LOCUS       DACCVH010000172         1819 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.181, whole genome shotgun sequence.
ACCESSION   DACCVH010000172 DACCVH010000000
VERSION     DACCVH010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.181"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            212..808
                     /locus_tag="IVV98_002884"
     CDS             212..808
                     /locus_tag="IVV98_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7808460.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(866..1348)
                     /locus_tag="IVV98_002885"
     CDS             complement(866..1348)
                     /locus_tag="IVV98_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808461.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1454..1651)
                     /locus_tag="IVV98_002886"
     CDS             complement(1454..1651)
                     /locus_tag="IVV98_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808462.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT          614 a          364 c          275 g          566 t
ORIGIN      
        1 tttttcaaat aagcaaaaat tcctaaaaca caacaatgaa agcgataact aagaaaatcc
       61 ttacataacg atttttctta ttaaaattgt tttttgaact tcgcttattt tttgtgagca
      121 tatctgttta cttacttttt gtaaggtgct atacttcatt tcgtaatcaa ttaaaaaaat
      181 gcaaaacgca aatcaaagga gaaattttat tatgacaact tttactgaca ctttgaaaaa
      241 ccgccgttca atctatcatc taggacgtaa tgtttcactt tctaatgaag aattaacaac
      301 tttgatcaaa gaagcaatta aagaaagccc aactgctttc aatgctcaat caacacgcgc
      361 agttatcctt ttcggagatg cacatgaaaa actttgggaa atcactgaag aagcacttcg
      421 cccattgact ccagcagaag ctttcccaaa tacacaaaac aaattagctg gtttcaaaaa
      481 tggttatggt acagtattat tcttcaaaga tactgacgtg gtaaaaggtc tacaagaaca
      541 atttgaatta tatgcagaca acttcccaga ttggtcagaa caatcaaacg gaatcgcaac
      601 agctaatact tgggtagcat tagttgataa aggattgggc gcaaacttgc aacattacaa
      661 cccagttatt gacgaagcag ttgcaaaaga atggaatatc ccttcaaact ggaaactacg
      721 ttcgcaatta gtattcggtt caccagaaac accggctgag gaaaaagaat acatgaacga
      781 tgccgatcgc ttccgcgtat ttggataatt ttatttgaaa taaaaaacag aggttgtgac
      841 aaacatcttg tcgcaacctc tgtttttatt ctggatcaat cataatatca atctctgcct
      901 catcgtttaa gcgttgggac aaaaatggaa ctaattcttc taatgatgca gaaaatttca
      961 gcatcggtcc tcgccatccg tttcggaaaa aattcatttt tacgatttta gaaccttttg
     1021 gctgatataa tacaatttta ttgatctcag aaaaaggaac accttttttg tcaaagctat
     1081 tcaaaacaag tccttcttct gtgattcctc tactgtccaa caaaaaacta ataaaaatca
     1141 ttgctgacaa gatccctttt gccaattcat ctgctgtagg atgactgatg agtgtatacc
     1201 aaatgactag tgacactaag aagggtatca ccaagtagac ccatcgattt cgcacagtcc
     1261 gataaataat ttcttttcga accagccaaa gaaataaaaa catcacaaca acgaataaaa
     1321 acaatagaac cgtaaagaat gttaccatga caactcgcct cgctttttct tctccagaaa
     1381 ataggaaaag aatactgatt taccttctca aagaaattgg acttgcagca cgccgcacgt
     1441 ccaattgttt tctttattca aatgtatcat attttgcaac aaccatgctt gctttttcat
     1501 ctaataattc ttggtcctct gcagcacatt gggcaacttt gaccacggcg cagtttgtca
     1561 tttttgatac aacttcacca atgaccgttt ttgtaaaacc aattggtttg catgcatatt
     1621 gttctcctaa attaatcatt tcttccgtca tcaaaatcct cctaaactgc tggaactttt
     1681 ctccacatta ccactgctat ttctttggag atttaactca ttgattttta tttacagtta
     1741 aaaatcaacc ttacaggcat tatagcgtac tgttttcgtt ttcacaatta aaacagctgt
     1801 tgtatttaga agaattttt
//
LOCUS       DACCVH010000173         1788 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.182, whole genome shotgun sequence.
ACCESSION   DACCVH010000173 DACCVH010000000
VERSION     DACCVH010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.182"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            57..197
                     /locus_tag="IVV98_002887"
     CDS             57..197
                     /locus_tag="IVV98_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7808463.1"
                     /translation="MSDSIEKMTLKKLADELGVSKNTVRNQLVNSGFDLAQYKEKNAV
                     VN"
     gene            complement(534..950)
                     /locus_tag="IVV98_002888"
     CDS             complement(534..950)
                     /locus_tag="IVV98_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808464.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGILIGTNSKVYQETKEKI
                     EKQLNPSKRNQPKNRQKETNQTFTSKNFDPTNFLKR"
     gene            complement(952..1233)
                     /locus_tag="IVV98_002889"
     CDS             complement(952..1233)
                     /locus_tag="IVV98_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808465.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNRYLKVLIEND
                     FDHALMHYKKDQFDLLLEKFIAIQEKNTETLNEYVRTNNQLIETLIGGR"
BASE COUNT          517 a          256 c          354 g          661 t
ORIGIN      
        1 aaacgagaat tagatacatg gcttcaagga cttgatgtga cggaagtagg tgctgaatga
       61 gtgattcgat agaaaaaatg accctaaaaa aacttgctga tgaattgggt gtatcgaaaa
      121 atacggtgcg caatcaactg gtcaattcgg gatttgacct tgctcagtat aaagaaaaaa
      181 atgcagtggt caattgaccg aaatttatgt ctttgggttt tggggtttta aaacgaaaaa
      241 aagggggcga ttttcgcccc ctttgctcta tgtgaaaaat ttgttatact tattttatcc
      301 ttaaaacata ccaatctttt tcttatttag ctgctcgtac gagcagcttt ttttacgatt
      361 atgaattcaa atcatgtatt tataattttt ttgtttttat ctttttttct gttatttctt
      421 ctgaaattcg tttttttcat tcaattggtt actatcttat tgtaaatgtt gctattaaga
      481 tggtgatcct acccaaaaaa taaaccagga atttaaatct cctggtttat tttttatctt
      541 tttagaaaat ttgttgggtc gaaattttta gaagtaaatg tttgattggt ttctttttga
      601 cgattttttg gttgatttcg tttggaggga ttaagttgtt tttcaatttt ttctttcgtt
      661 tcttgataca ctttagaatt tgtgccaata agaatacctg tatcttttag atataaatca
      721 gcaaattctg caatgatttc ggacatgatg gaaatttctt ttcccatagc atttagtttg
      781 gcttggttgc tggtagtcgt agtattggta tcaggttcat aactcataca taaaaaacga
      841 atggcttccg agtaattgtt gatatctgga tttctttcga taatggaatc taaaacgtcc
      901 acgtgactgg gataaagggt aacgtgtttt tgaacagaag tttttctcat gttatcttcc
      961 tccgataagt gtttcaatga gttggttgtt tgtacgaaca tattcattca gcgtttcagt
     1021 atttttttct tgaatagcga taaatttttc gagtaataaa tcgaattgat ctttcttgta
     1081 atgcataagt gcgtggtcaa aatcgttttc gattaggact tttaagtagc gatttcgact
     1141 ccattttttg ccagttttat ttgtgagttc ttggcaacgt ttgtctattt ttgcaataac
     1201 ctttgaatcg atcttccgaa ctaaaatgtc catagaaaaa ctcctttcgc atttgtgtat
     1261 aatttatgta tatcatacga atatagtatt tgtatagctg ttttttgcta aaatactata
     1321 cataagctag ccacgatggc gaaaaagtga tatcaaattt ttttctgaga aacgtgatag
     1381 gcacagccta tctacccact ttttttagaa agtgggtaca cgtttcctta tgctctttat
     1441 aaaatggtga tgtgcgactt ttttctgttc gtaaaaataa aaaaagttta cgaaaatgaa
     1501 actaaactga acgattatga cgggcatgta atcaagatga aatgatttta taagcgcgta
     1561 ttttgcgttc taagacgttt tagcgttcat ttcgtttagt tatcggcaca atcgttaaaa
     1621 cacgtaagag aagcgagaat ggagcctgta aggcgactgg tagcgaaacg gcgtgttaga
     1681 ttgtgcaagc cgagaactga atgaaatgaa gagcggaagc gtgaaataat ttcggcagga
     1741 ggaggctcaa ggggttcggg gaatgaaatt ccctgaggtc tttttatt
//
LOCUS       DACCVH010000174         1664 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.183, whole genome shotgun sequence.
ACCESSION   DACCVH010000174 DACCVH010000000
VERSION     DACCVH010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.183"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            131..505
                     /locus_tag="IVV98_002890"
     CDS             131..505
                     /locus_tag="IVV98_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7808466.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="IVV98_002891"
     CDS             complement(619..1248)
                     /locus_tag="IVV98_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7808467.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="IVV98_002892"
     tRNA            complement(1382..1454)
                     /locus_tag="IVV98_002892"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DACCVH010000175         1659 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.184, whole genome shotgun sequence.
ACCESSION   DACCVH010000175 DACCVH010000000
VERSION     DACCVH010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.184"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            81..1604
                     /locus_tag="IVV98_002893"
     CDS             81..1604
                     /locus_tag="IVV98_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP7808468.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          608 a          269 c          341 g          441 t
ORIGIN      
        1 tagaaacata tgcagagtat tcaccggaac agatcaatcg tatgatcgat caaatggagt
       61 ctgtcaaaaa agaaagttat ttggacccta ctgtttttga agcagaggaa catatccaaa
      121 aagtcattca taaaatgttc cgtccagaca atgcctatac aaaatttgat tttcgaaatg
      181 gccgtccaac gaagtctgcg atcttaacca cgagttccat tgatatggcc aaaaagtatt
      241 atcgggccat caaagagatg acgaaagaat ctgattggtt aataaaagag tttcccaatc
      301 agcctatccg tgaaggacga acgatggagg atcctgattt cccacgaatc gctattacct
      361 attcattaga agaaaatagc cgagattcaa gtgcccaaca agaagaaatg caaaaaatta
      421 ttgaggaata taatcagtat tatgatactg cctggtcact agcagacatt gagcgttata
      481 acggagacat caataatcgt ttggcacgaa aaagagcgga attcaaacaa tttgggaaac
      541 aaatcgattt agtaatcgta gtggatcgtc tattgacagg ttttgacgcc cctacgattc
      601 aaaccctatt tgtggatcgt aatctagagt atgcaggatt gatccaagcc ttttcacgta
      661 cgaaccgtac gtatcctgaa aaaacaaaag gactaattgt tactttccga aagccagcga
      721 caatggagaa gaatgtcgag gatgcgacaa aactgtattc agaagctaaa gaagaatcgg
      781 gtttgattta tccaagttac caagaatcca aaaaaagatt caagcaagca tatggtaagt
      841 taaaagaggt ttcatccatg gaatccattg atgaacatac gccacttgaa atccgtatcg
      901 agtacgtcaa agcatttcaa gaattgaatc gtgcgtatga atcgttagtg acttatgatg
      961 attacaatga tgacatggtg caatcttcaa ctttgaacaa tcaaattcaa cttttggaag
     1021 aacaaattgg cgtgtacgag accgtgaagg gttcattgat ggaggaagaa ccagaaaaag
     1081 agggagaaga tttttcaacg atcgaatttt atagtgaaaa taccactaag ttgtatgata
     1141 ttgattctac ttatattgat caattactag gaacttatgc tgcgaatagt tcagatgcac
     1201 gagaagaaat tgaaaaagct ttggctaaat tgaataaaac agaaggagtc aaagaagttt
     1261 accgacaaat tttaaatgca tttgatgtgg ggactttaga tagtaatgaa gatatctttg
     1321 tcattaaacg tcgctatttt acacaagcaa gtgataattt gattcatgcc ttttccaatg
     1381 agtggtttgt ttctgagaaa gaattacatg cttctaatct gcaatatatg ccaggtgaag
     1441 atccaattcc taatatgaaa gcaattatca acagtaagga ttacgaagga tataaagcca
     1501 aacatccaga agcgaaacca tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa
     1561 tgttagatga tgagttgatt ccacttgaaa atgaattgag gtaaacgaga agagttaaga
     1621 aaattgtacg attcaaagat agtagtaaag tggaagtgt
//
LOCUS       DACCVH010000176         1642 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.185, whole genome shotgun sequence.
ACCESSION   DACCVH010000176 DACCVH010000000
VERSION     DACCVH010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.185"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>1642)
                     /locus_tag="IVV98_002894"
     rRNA            complement(<1..>1642)
                     /locus_tag="IVV98_002894"
                     /product="23S ribosomal RNA"
BASE COUNT          348 a          507 c          350 g          437 t
ORIGIN      
        1 taagtcctcg atcgattagt atcagtccgc tccatacatc actgtacttc cactcctgac
       61 ctatctacct gatcatctct cagggatctt actttcttaa agaaatggga aatctcatct
      121 tgaggtgggc ttcacactta gatgctttca gcgtttatcc cttccctaca tagctaccca
      181 gcaatgccct tggcagaaca actggtacac cagcggtaag tccatcccgg tcctctcgta
      241 ctaaggacag ctcctctcaa atttccaacg cccgcgacgg atagggaccg aactgtctca
      301 cgacgttctg aacccagctc gcgtgccgct ttaatgggcg aacagcccaa cccttgggac
      361 cgactacagc cccaggatgc gacgagccga catcgaggtg ccaaacctcc ccgtcgatgt
      421 ggactcttgg gggagataag cctgttatcc ccagggtagc ttttatccgt tgagcgatgg
      481 cccttccatg cggaaccacc ggatcactaa gcccgacttt cgtccctgct cgacttgttg
      541 gtctcgcagt caagctccct tctgccttta cactcttcga atgatttcca accattctga
      601 gggaaccttt gggcgcctcc gttacctttt aggaggcgac cgccccagtc aaactgccca
      661 tctgacactg tctcccacca cgattagtgg tgcgggttag agtggccata acgcaggggt
      721 agtatcccac cagcgcctcc atcgaaacta gcgttccgat ttctacggct cctacctatc
      781 ctgtacatgc ggtacagaca ctcaatatca aactacagta aagctccatg gggtctttcc
      841 gtcctgtcgc gggtaacctg catcttcaca ggtactaaaa tttcaccgag tctctcgttg
      901 agacagtgcc caaatcgtta cgcctttcgt gcgggtcgga acttacccga caaggaattt
      961 cgctacctta ggaccgttat agttacggcc gccgtttact ggggcttcaa ttcgtacctt
     1021 cgcttgcgct aagcactcct cttaaccttc cagcaccggg caggcgtcag cccctatact
     1081 tcatcttacg attttgcaga gacctgtgtt tttgataaac agtcgcttgg gcctattcac
     1141 tgcggctgat cgtatgatca gcaccccttc tcccgaagtt acggggtcat tttgccgagt
     1201 tccttaacga gagttctctc gctcacctta ggattctctc ctcgactacc tgtgtcggtt
     1261 tgcggtacgg gccgctgttt tctcactaga agcttttctc ggcagtgtga catcaggaac
     1321 ttcggtacta ttatttccct ccccatcaca gcttgtcctt aagaaaagaa gcatttgact
     1381 cctcttcaga cttactgctt ggacagacat ttccgatcgt ctgcattcct tagcctcctg
     1441 cgtccctcca ttgctcaaac aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg
     1501 cctacgcctg tcggcctcgg cttaggtccc gactaaccct gggcggacga gccttcccca
     1561 ggaaacctta gtcattcggt ggacaggatt ctcacctgtc tttcgctact cataccggca
     1621 ttctcacttc taagcgctcc ag
//
LOCUS       DACCVH010000177         1606 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.186, whole genome shotgun sequence.
ACCESSION   DACCVH010000177 DACCVH010000000
VERSION     DACCVH010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.186"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(61..279)
                     /locus_tag="IVV98_002895"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="IVV98_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="IVV98_002896"
     CDS             complement(545..739)
                     /locus_tag="IVV98_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808469.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
BASE COUNT          568 a          242 c          213 g          583 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaata
//
LOCUS       DACCVH010000178         1590 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.187, whole genome shotgun sequence.
ACCESSION   DACCVH010000178 DACCVH010000000
VERSION     DACCVH010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.187"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            76..1542
                     /locus_tag="IVV98_002897"
     CDS             76..1542
                     /locus_tag="IVV98_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAP7808470.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          441 a          291 c          333 g          525 t
ORIGIN      
        1 ataagttttt tagttaaatt tttcggtaaa gatgtataat attttctgaa aatttaaaga
       61 attggggtat agattatgga aaaacagcaa gacaagggct tcttcgggca gccgaaggga
      121 ttgtcaactt tgttcttcac tgagatgtgg gaacgattta gttattacgg tatgcgtgca
      181 ttacttatct attatatgta cgatacagtt gccaacgggg gacttggatt accacgagca
      241 acagcattag ctatcatgtc gatctacgga tctttgatct acatgtctag tatcgtcggc
      301 ggatgggtat ctgaccgagt gttaggagca aaacgcactg tattcttcgg tggagttttc
      361 attatgcttg gccacatcgt cttggcttta ccatttggtg taagtacatt gtttgtttcg
      421 atggcattga ttattatcgg aaccgccttt ttgaaaccaa atgtttctgg catggtcgga
      481 catctttatt caaagactga cttgcgaaga gatgcaggat tttcgatttt ttacatgggt
      541 gtcaacttag gggcattatt agcaccacta atcgttggta caatcggtca agaatataac
      601 tatcatttag ggttctcttt agctgctatt gggatgttct ttggattatt acaatacatc
      661 atccaaggac gcaagacatt agacggagtg ggtacaacac cgccgaatcc tttgacaact
      721 gaagaacgta aaggattcat ccgtaacttg atcatcgcac ttgttgttat cgctgcagta
      781 ttcggcgggg cacaactaac tggtcatctg acaattgact tttttgtcaa tacaatcagt
      841 gtattgggga ttatcttacc gttgtattac tttatcaaaa tgctgacttc aaaagatgta
      901 actgctgaag aaaaaccaag agtatgggct tatatcccat tattccttgc agcaatcatt
      961 ttctggtcat tacaagaaca aggttcatct atcttagctt tatttgctag tgaacgtaca
     1021 caatctacgc tatttggtgt aacgatccaa gcaagctggt atcaatcatt gaatccaatt
     1081 ttcatcttta ttctgacacc agtattcgta acgatgtgga cgaaacttgg tgaacgtcaa
     1141 ccatctacag tagtgaaatt ctctcttgga cttttatttg caggattatc gtacttgcta
     1201 ttgatgttgc cgggtatgct ttatggtaca agtggaaaag taagtccatt gtggttgttg
     1261 ggaagtttct tcatcgtggt tattgctgaa ttgtgtcttt caccagttgg tttgtctgtg
     1321 acaacaaaat tagcaccacg agcatttgaa tcacaaacaa tcgctatttg gttcttagct
     1381 gatgcttctt cacaagcaat caatgcacaa attgcacgct tctacacacc gggaacagaa
     1441 tctgcttact tcggtattat cggtgcagta gcaatcgtcg gtggtatctt gctatttact
     1501 gtgaaagaac caatcaaaaa actaatgggc tctattcatt aatcaatgaa cataaaaaca
     1561 ggaattgctt atttgcagca gttcctgttt
//
LOCUS       DACCVH010000179         1550 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.188, whole genome shotgun sequence.
ACCESSION   DACCVH010000179 DACCVH010000000
VERSION     DACCVH010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.188"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            90..1148
                     /locus_tag="IVV98_002898"
     CDS             90..1148
                     /locus_tag="IVV98_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAP7808471.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
     gene            1150..>1550
                     /locus_tag="IVV98_002899"
     CDS             1150..>1550
                     /locus_tag="IVV98_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808472.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFS"
BASE COUNT          511 a          184 c          254 g          601 t
ORIGIN      
        1 ctatttataa ttttggatat ttgctgatta ctttgatagt aatttttcct gcagactttt
       61 cacaaagtga agaggaaaaa aagaaaaaaa tggtgtattt taataatgtt ttcattatca
      121 taattttttt agctgcgcta atatctatct atcaatttat ttttttgatt tcttatcatg
      181 tcccaacagg aacgccagga ttacttgcaa gacaaggttt tattgaacat cggttatttg
      241 gtgtctatac aagtccaaat gttggagcta tgtttggata tacttctatt attttaagtt
      301 taattagtgt attaatttca aaaataacaa aaacgattcg tgttttttat atgatgaatt
      361 ttatcgtaca aatattttat attacacttt cttcgtctag aggtgcccag gtagtaattt
      421 gttctttttt agtattattt cttttgttgt ttgccaattc aaaatttaga aagagcatta
      481 gagaagtact acctgtaaaa atcaaatgga tggtaagcat attattagtt ctattggtat
      541 atttttcttt tggtactaat tatgctaagg attttttagc aacaattcct gtatcgattg
      601 atagaaaagt agaagttata gagtcaaatg aatcagataa aactccactt ccagaaaaag
      661 aagtaatatt acagcattct agtgataact ccgaaatttc agctggtcgt tttacgattt
      721 ggaaagctgc gcttaaagtt ataagaccaa ctttgttatt tggttatgga gagaccgatt
      781 tctatgggaa tagcgatgca aaatttttga aaaaagtaga tcttgatact acagatgtga
      841 atgaactaaa aagagcacat ggaaacatgc ataatggatt tcttcaagta cttgtatcaa
      901 gtggtataat tgcttttata tgtatctatg ctttctatgt gttaaatatc tttagtttac
      961 tcaaaacatt ttttagaagt aaagtgaatt atgcgtttct tggtattgtt ttaattttta
     1021 tactatctat ttttatagat gaaatggtgg aggctcatgt acttttcaat aagcgcgatg
     1081 tcatttcaat tgttttctgg tattatttgg gaagcatttc ttacttgtat ttaaaaaagg
     1141 agaattaata tgaagacagc tttcattgct tggactcctt tacatttgat taatatatta
     1201 aatgtttatc aaaattttta ccgagaatca aaaggagatt tatttattta ttctgaattt
     1261 gaaaacgcta gaagatatag tgagcgtata aaagaattag ggctatttaa tgatgttgtt
     1321 tttgtgaatc accggaaaat cggttcttcc tttaaacgta aaattaactt gttaactaac
     1381 cataatcaat ttttctcgga tgatttatcc gtttatgatg aaatttttat acagggggaa
     1441 aattatttca caaaaatact tttctccaat gtttacaaaa aaaatccaga tgtaaaacta
     1501 aattatatag aagatggttt gggtacttat ttgaagaaga gtatattttc
//
LOCUS       DACCVH010000180         1487 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.189, whole genome shotgun sequence.
ACCESSION   DACCVH010000180 DACCVH010000000
VERSION     DACCVH010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.189"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            476..727
                     /locus_tag="IVV98_002900"
     CDS             476..727
                     /locus_tag="IVV98_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808473.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            761..1039
                     /locus_tag="IVV98_002901"
     CDS             761..1039
                     /locus_tag="IVV98_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808474.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
BASE COUNT          533 a          198 c          275 g          481 t
ORIGIN      
        1 atacaaataa ttggtttatt ctggcaggcg taatgctttt ttctagtttc tatttattta
       61 gtaatgctct attagcacag cgagggaaat ataagtttaa aatattagat tagatattat
      121 ttttagaggg gataaatata aaatgaaaag aggttattta taatggaaaa agtattacca
      181 attaagagct actgtattcc aaggcttttc atcatagaat ttcaaaagta aagacatgtg
      241 tttcacaaat agtgtctatc ctggctaaat aattcttcca ctatctgctt taatttcagt
      301 agacttttcg gcaagttatt tgctaatgag atgaatagag attacaactc gcctataacc
      361 gcttaaaaca agctttttta aagtatagtt agcaagtcgt attcatatgt tcaaagagga
      421 gggcttatga actttgaatt cattccgtgt gaacagaaca gtagggggaa gtaaaatgaa
      481 agaaaagcct ataaataaat ggtcattgta taaaaattca atgtttggag ttgttatctt
      541 tggtgtttgt gctggattat tccttttcat attattacaa acggtgactc ttttctcttc
      601 taatcctact tatggatgga gagacagtat agccttaggg atgtttgcgg gaggatatgg
      661 attcttattg ttgttctcaa ttctcacact aagtccaatc catggactca ttcaactttg
      721 gaagtaagaa cgagccttaa acttttcgtt ctcggaagaa atggaaaaac acaacataac
      781 aggcagtatg tatgtggatg atcaatggtt tatcagcact gatgaggtaa aaatagctgc
      841 cattaggaga gattacctgc agaaaattca taaaataaaa gatcctaatg ggaaaaaggc
      901 aaggttaatt ataactttga taacatctaa tggtaagaag ttaaaacttg caggatcata
      961 tgataatgtt aaaaagttcg aacattggta tctgcaaaaa gacagcatta gtcttaataa
     1021 acaatttgaa aaaaattaat caaagtcatc ggcaacacga ataatttgac atcttgatat
     1081 tgtgatataa gcaaaaacgg catttctgag accgaacagc ataaaaaatt taaatgttgg
     1141 aatttatata agcaaaaccc aagaagctag atgcgataga gcatttaatt tcttggggtt
     1201 ttgcttggga atcagcatat caattaaaat gatcatctcg gtatttcaaa agtgggtacg
     1261 attacaaata gttggagcaa aatagtgggt aaaattacca ttccagtgtc tgtcttgcct
     1321 ctttttcgtc aatcacaaat agacgagatt cataggaaaa atcgatacag ggtatgattt
     1381 caatgatatt atgaccaatt acaaaataga ttgataaagc attttttgca tttttataat
     1441 agtttattga taataatgta tgagatacag tataatgatt taaaagg
//
LOCUS       DACCVH010000181         1483 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.190, whole genome shotgun sequence.
ACCESSION   DACCVH010000181 DACCVH010000000
VERSION     DACCVH010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.190"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            64..972
                     /locus_tag="IVV98_002902"
     CDS             64..972
                     /locus_tag="IVV98_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAP7808475.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1483
                     /locus_tag="IVV98_002903"
     CDS             972..>1483
                     /locus_tag="IVV98_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808476.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGV"
BASE COUNT          511 a          216 c          345 g          411 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgt
//
LOCUS       DACCVH010000182         1480 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.191, whole genome shotgun sequence.
ACCESSION   DACCVH010000182 DACCVH010000000
VERSION     DACCVH010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.191"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            64..972
                     /locus_tag="IVV98_002904"
     CDS             64..972
                     /locus_tag="IVV98_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAP7808477.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="IVV98_002905"
     CDS             972..>1480
                     /locus_tag="IVV98_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808478.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DACCVH010000183         1466 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.192, whole genome shotgun sequence.
ACCESSION   DACCVH010000183 DACCVH010000000
VERSION     DACCVH010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.192"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..511)
                     /locus_tag="IVV98_002906"
     CDS             complement(<1..511)
                     /locus_tag="IVV98_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7808479.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSL"
     gene            1164..1259
                     /locus_tag="IVV98_002907"
     CDS             1164..1259
                     /locus_tag="IVV98_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP7808480.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
BASE COUNT          483 a          297 c          232 g          454 t
ORIGIN      
        1 ttaagctcct aaactcttca atacgaacta cataataacc agtagaacgg tactgcataa
       61 gcagtcggaa tagagttttt gcatacgtag aacgcaacga cgtgaaagca gataattcaa
      121 atctactaaa ttcagctgtt aaaccattaa taatatattc taggtccgga ttaacactga
      181 cttcaacaaa cttttttgtt ttattgattt caaaaccagt aaacaaaaca aagtagcgaa
      241 tagaatcctc atcttcagta cggtaagtaa gattaagcat atctttatag agcttttcta
      301 aatcaccgac aaaggctttt gtagcagtca tcttataatc acttaactct tttaattcct
      361 cgaaagaaaa tctaactttt ttcaaaccac gatctttcat acgagcgcat aatgcaaaaa
      421 ataaatccat ctgcttagca ttgaaatttt tcagcggtac taaattcaat tcattttgat
      481 atttgactgt taattccgtt ttttcatcca ttcctttctt ccccccttac aaataaataa
      541 taacctttaa caaccaactc gtaaataggt tggttgttat tatacaaaag gatattagta
      601 ctcagataaa aagttgttag tactcagata aaaagttgtt agtactcaga taaaaagttg
      661 ttagtactca gataaaaagt tgttagtacc cttctgtatc cgttgggaga gtaaggctca
      721 actgccccct aaaaagggtt ctaaaaaatc tttaaaaaat aaataaaata aacgcgcgcg
      781 cgcgagcaaa atttcccgcc aaaaaatcac ccacttttta aaataaacag gttcgcgcat
      841 gatattaaac tgccaatcta gctccctatg gtcgctgtaa gaaggagtga tcgctacgct
      901 ctcacatttt acttgcagca gtcgccttta ggctccttcg ccaaaaataa ttcattaggg
      961 actcctttgt ggcgtcctga gagctcgtct aagccgttct aagacaagat tcgataaaaa
     1021 ctatgtcctt cgttctaaag cgccttacag gcggtcaggg caagccctaa caaccccaag
     1081 gcaataaaaa acttaggctt atttttgctt ttttattgta taattgattg tcgcctatcc
     1141 gacagtcttg cgactggaag gaggtgtgtt tcgtgttcac taactttatt tgctcccttc
     1201 ttgttgggct tttaagcgct ttgttcagtt actggttgaa taaccgaaac aagaagtaaa
     1261 acttaattaa ggcgactcag cccacaaaaa aagccccaga gaatccgacc tctctggggc
     1321 tttcgtgtgt ttcgtgttca cttatttgca atcaaattat aacagaaata aatatttatt
     1381 tcaaaaatat cctacaaaag tctaaaatcc gtaattattt cttatatgca acatttacaa
     1441 ataaagtcgc tctgagagct cgtatt
//
LOCUS       DACCVH010000184         1375 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.193, whole genome shotgun sequence.
ACCESSION   DACCVH010000184 DACCVH010000000
VERSION     DACCVH010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.193"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(164..>1375)
                     /gene="cadA"
                     /locus_tag="IVV98_002908"
     CDS             complement(164..>1375)
                     /gene="cadA"
                     /locus_tag="IVV98_002908"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP7808481.1"
                     /translation="LVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVSG
                     AAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTET
                     VVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLPT
                     TNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYLV
                     IADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKVQ
                     RLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPSK
                     IAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLNA
                     MRSLHVKKEDE"
BASE COUNT          399 a          304 c          220 g          452 t
ORIGIN      
        1 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
       61 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
      121 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
      181 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
      241 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
      301 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
      361 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
      421 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
      481 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
      541 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
      601 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
      661 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
      721 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
      781 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
      841 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
      901 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
      961 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     1021 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     1081 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     1141 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     1201 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     1261 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     1321 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaa
//
LOCUS       DACCVH010000185         1366 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.194, whole genome shotgun sequence.
ACCESSION   DACCVH010000185 DACCVH010000000
VERSION     DACCVH010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.194"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            82..>1366
                     /locus_tag="IVV98_002909"
     CDS             82..>1366
                     /locus_tag="IVV98_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP7808482.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          466 a          263 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatca
//
LOCUS       DACCVH010000186         1355 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.195, whole genome shotgun sequence.
ACCESSION   DACCVH010000186 DACCVH010000000
VERSION     DACCVH010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.195"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            127..579
                     /locus_tag="IVV98_002910"
     CDS             127..579
                     /locus_tag="IVV98_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808483.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="IVV98_002911"
     CDS             593..1282
                     /locus_tag="IVV98_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808484.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
BASE COUNT          477 a          181 c          266 g          431 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaat
//
LOCUS       DACCVH010000187         1320 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.196, whole genome shotgun sequence.
ACCESSION   DACCVH010000187 DACCVH010000000
VERSION     DACCVH010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.196"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..347)
                     /locus_tag="IVV98_002912"
     CDS             complement(<1..347)
                     /locus_tag="IVV98_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808485.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAIL"
     gene            635..1288
                     /locus_tag="IVV98_002913"
     CDS             635..1288
                     /locus_tag="IVV98_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7808486.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          494 a          165 c          239 g          422 t
ORIGIN      
        1 atgagaatcg cctgcttcag ttcctttgtt agttgatgat gttcatcaac taagtccgtt
       61 ttcgcagaaa aggtctgccc acaatcatag catagaaaac gggtacgttt taattctaaa
      121 atagtcaact tttctttgac tttcaatatc tgagtacgtg tcgtatagga accgttgcgg
      181 ataatacgaa tcgatccaca gtgttcacaa tgggaaggtg agtcatccaa tctcccttta
      241 ataaactgcg cttgaacgcc tttatattct ttttcaatca gccattcttc atcaaaaaat
      301 aaatgtttat ctgttaatcc gagtaatttt ctagtatgat tatccataga gcgactcctt
      361 tggtagggtg atgttttggt cgactaaatt ttaccaaaag tgagtctctt tttgagttga
      421 aacgaagaaa aagtgttagt agaaaatcgc cttcgatttt ccaacaacac aaaatattat
      481 agaacccttt attctaaagg atttcaaggt gtctgtttgc atttattaga aaaaagaaaa
      541 agtattggca acagaaggtg tcaccaacac tagatattat agagccataa tatgctgtat
      601 aatatctagt gtataggctt aagtggaggt atatatgaaa atattaactg ttgaagatga
      661 taatatgata agagagggaa taagtgaata tctttcagaa tttggatata ctgttattca
      721 agctaaagat ggaagagaag ccttgtcaaa atttaatagc gatataaatt tggttatctt
      781 agacattcag atacctttta taaatggttt agaagtgttg aaagaaatta gaaagaaaag
      841 caatttacca attctaatct tgactgcatt tagtgatgaa gaatataaaa ttgatgcatt
      901 tactaattta gtagacggat atgtagaaaa gccattttca ttgccggtct taaaagctag
      961 aatagattct ttaattaaga agaattatgg acatttagag aagtttgaat ataaggatct
     1021 atcggttaat tttaatagct atacagctaa aataaatggt gaagaaatag atgtaaatgc
     1081 aaaagaacta gaagtattaa aatgtttatt ggataataat ggacaagtgt taacaagaat
     1141 gcaaattatt gattatgtat ggaaagatag cgaagaaact ccttatgatc gagtaataga
     1201 tgtatatata aaagaactta gaaaaaaatt acaattagac tgtataacta ctataagaaa
     1261 tgtaggatat aaattggaga gaaaatgaaa aaattaaaga tatttccaaa aatgttcata
//
LOCUS       DACCVH010000188         1311 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.197, whole genome shotgun sequence.
ACCESSION   DACCVH010000188 DACCVH010000000
VERSION     DACCVH010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.197"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            102..>1311
                     /locus_tag="IVV98_002914"
     CDS             102..>1311
                     /locus_tag="IVV98_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7808487.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          412 a          258 c          252 g          389 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta a
//
LOCUS       DACCVH010000189         1255 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.198, whole genome shotgun sequence.
ACCESSION   DACCVH010000189 DACCVH010000000
VERSION     DACCVH010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.198"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            36..908
                     /locus_tag="IVV98_002915"
     CDS             36..908
                     /locus_tag="IVV98_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7808488.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          377 a          230 c          303 g          345 t
ORIGIN      
        1 agtgatttca ttctaaaata aagggagaaa tgtctatgct atacggtgca attgaagcag
       61 gcggcacaaa atttgtgtgt gccattggcg atgaagaaat gacgatcaag gaaagagtga
      121 gctttccgac aacgacacct gaggaaacaa tgcctttagt cattgacttc ttcaaacaat
      181 accaagcaga tttagcaggg attgggattg gctcatttgg gcctatcgat atccatcgcg
      241 attccgccac ttatgggtac attacctcga ccccgaaatt ggcatggcaa aattttgatt
      301 tcatcggtac catgaaaaaa gaatttccga tcccgatttc ttggacaaca gatgtcaatg
      361 cggctgccta tggtgagtat gtcttcggca gtggcaaagg attgagcagt gtcgtttact
      421 atacgatcgg tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt atcgaagggt
      481 ttagtcatcc agaaatgggg catatgctcg tcgtccctca tccaaaagat gactttgctg
      541 gcagctgtcc atttcatggc aactgtttag aagggatggc cgctggaccc gccatcgaaa
      601 accgcttagg gaaaaaagga caagaggttg cagaagatga tccttattgg gaaatcgaag
      661 cctcctatat tgctcaatgt gcctacaata caaccttgat gttttctcca gatgtgatca
      721 tttttggcgg tggtgtgatg aaacaacgcc atatgctgca aaacgtccac gacgcatttg
      781 caaaattggt caatgggtat gtcgaaacac ctgagttaag caaatatatc gtgaccccag
      841 cattagaaga caacgctgga acgctcggtt gtttggcatt ggctcgagaa gcggtcttac
      901 attcataaac gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga tacaactgaa
      961 aatttagtca taaccagtta ggcagagtgc ttaactggtt tttgttttac ttggaagatc
     1021 aagccttgaa tgagataaat tcttgctcga aagttatgga aatttcgata gccgtaggcc
     1081 acttgtattg tgcaatagtt ttttacaaaa aaaagggggt gcggatattt ttttggacct
     1141 ttttaacaaa taggttctgt tgcaaagttt taaatctact atcagataag gtagaataat
     1201 agaaaaagat agcaggagga atgacgatga gtcattttaa aggaaagcaa tttca
//
LOCUS       DACCVH010000190         1245 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.199, whole genome shotgun sequence.
ACCESSION   DACCVH010000190 DACCVH010000000
VERSION     DACCVH010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.199"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            199..741
                     /locus_tag="IVV98_002916"
     CDS             199..741
                     /locus_tag="IVV98_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808489.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            831..>1245
                     /locus_tag="IVV98_002917"
     CDS             831..>1245
                     /locus_tag="IVV98_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAP7808490.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          513 a          141 c          238 g          353 t
ORIGIN      
        1 ttgatgaagc agatcccaaa gggctgcttc atcaattttt tcgtaagtgt ccgtacactt
       61 actgtgcttg ctcatatatt aatcgatcat atactaatcg tgtaagaaca actttaagca
      121 taatacttat attgttatac catagtttgg aaaaataaaa aattatattt catcaacgtt
      181 tcataaaagg tgtgtagaat gttattgaaa gtagctataa aatgctattg tgtaaaaaat
      241 aaaggaggaa taatttatga aaaaatagta ccaagaggag catgcctatt acttgcatta
      301 tgtttgagct taagcgcagt tgggtgtcaa aaaagtaatg aaaacaataa aataaaagaa
      361 ggacaatcca taagttctga agaggaaggc atgtcaatta atgcaaatgg caaaaatgaa
      421 acttttaagc catcagatta tacattggag gcaaagaaag aatatgttta tgaatattta
      481 gggcttaaat ttaaactctc agacaaattt agaaattata tagctgataa aaagatagcg
      541 atgttagatg atcaaagtcc tatagataaa gaactaaagt atgctatttt gacatttgag
      601 aaaatgacag aagaacaaaa gaatgcagtt atagaaaaga tgggcgatgg atataaaaat
      661 tggcaaaatg agcttgaaag aattgggact attggtatat ttgaaaaaaa tacatcagaa
      721 gaaaaaaatc taaaattata aaatgtgata ctcatactaa aataggagtt tcaagtgatg
      781 gaaaatacga ttgctattta agcacaaata gcggagctga aagtaatctt ctggatgaat
      841 taaaaagaac tgagattcaa attatagata aaaaagaacg tcctaaaaat ggttttgtgc
      901 tatcagaaaa aactgattta gaaaatacag aagcatttaa caaagaatcg gttaaagatt
      961 tacgtaaact accaacaaag gacataaatg gcaaggattt tacaagtaaa gattttgaga
     1021 agtatgatct tactatggta aatgtatttg caacttggtg tacagcttgt gtaaaggaaa
     1081 ttcctgattt ggttgaggtt cagaatgaaa tgaaaagcaa gggtgtaaat atcgttggag
     1141 ttgttacaga tcctgttgat gataacggtg aaaacaagga agcaattgaa aagtcaaagt
     1201 taatacatga aaagacaaag gcttcatatc ctttcttaat gccag
//
LOCUS       DACCVH010000191         1195 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.200, whole genome shotgun sequence.
ACCESSION   DACCVH010000191 DACCVH010000000
VERSION     DACCVH010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.200"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1076
                     /locus_tag="IVV98_002918"
     CDS             <1..1076
                     /locus_tag="IVV98_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7808491.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DACCVH010000192         1167 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.201, whole genome shotgun sequence.
ACCESSION   DACCVH010000192 DACCVH010000000
VERSION     DACCVH010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.201"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            281..973
                     /locus_tag="IVV98_002919"
     CDS             281..973
                     /locus_tag="IVV98_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP7808492.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          501 a          161 c          188 g          317 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tatactaagt agttcagttt tggagtacaa aatgacaaaa tgtacttcaa aatggactac
     1081 ttttttcatt ttaacttaca taccaaatta catacaaaat gatttataaa atgcaattga
     1141 aaatgataat tgaatgaaaa tttgtga
//
LOCUS       DACCVH010000193         1156 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.202, whole genome shotgun sequence.
ACCESSION   DACCVH010000193 DACCVH010000000
VERSION     DACCVH010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.202"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            237..>1156
                     /locus_tag="IVV98_002920"
     CDS             237..>1156
                     /locus_tag="IVV98_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP7808493.1"
                     /translation="MSKRGTIINEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     QEGKGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKVVPKEIDTWWRLELQ
                     LRRGKATDWHAMVHESLDSFASPHYLPEDVKVTDRMMITALITEHSYWGQIHRNSKYK
                     YRELLKQESQNDELTNHLRETFSESADDLKR"
BASE COUNT          397 a          183 c          249 g          327 t
ORIGIN      
        1 aggagtgcta taatcaaaga aaacgagaaa aaagagcaaa ataaaagccg aacggtgttg
       61 gaagcaccct tcggctaatt acggaaacta ctcacctagt tccgtaactc aaattcatta
      121 tacgaatatt tttaggtttc ttcaagctag agatttttgg atatggattt ttagagttac
      181 gtgaactctg gaaattcttt ccaaaaatct cttttttctt tgaggaggaa caaaatttga
      241 gtaaacgtgg cacgatcata aatgagtggg aaaaacttaa ccgcatatct aacaggcggt
      301 taaatgcaca aactatgtgc acccccttaa aaatgcaatg gtcaattgac cgaattacca
      361 ttgttggtac attaagggaa aatatttatt atcacactcc ccatgatgtg ttgattttag
      421 attttgaaca gcttatgcgt ctaaacgaag gtaacggata tttaaaagcg gttggaaata
      481 atggctggca attactagac caacatgagg aaaatatagc ttatattgag attcttaagt
      541 ttcaagaggg aaaagggcgg attgacttta accccaataa aattagccaa tttctggcgg
      601 gctcgatgaa gaactttatc catgatttat ttttagaacc acatttctca cgtgcagata
      661 ttgcttgtga cattattgac gtgccagatg atttcattac ccaatatcgg gtggttgatc
      721 ctgtttcttt caaaccaatt tacggtcggt ctgggaaact ggaaacagca tattggggaa
      781 gtcgtgctag tgaacgacag attcggatgt ataacaaaaa attggaacaa gaaagaaaac
      841 ggaaagttgt tccgaaagaa atcgatactt ggtggcgact agaattgcaa ttgcgaaggg
      901 ggaaagcaac tgattggcat gcaatggttc atgaaagttt agatagcttt gcaagtcctc
      961 actatttgcc agaagatgtg aaagtaactg acagaatgat gattactgct cttataacgg
     1021 aacatagtta ctgggggcaa attcatagaa attcaaaata taaatatcgt gaattgttaa
     1081 agcaagaaag tcaaaatgat gagttgacga atcatttgcg agaaacattt tcggagtcgg
     1141 cagatgattt gaaacg
//
LOCUS       DACCVH010000194         1107 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.203, whole genome shotgun sequence.
ACCESSION   DACCVH010000194 DACCVH010000000
VERSION     DACCVH010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.203"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            5..1087
                     /locus_tag="IVV98_002921"
     CDS             5..1087
                     /locus_tag="IVV98_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7808494.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          403 a          193 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaac
//
LOCUS       DACCVH010000195         1099 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.204, whole genome shotgun sequence.
ACCESSION   DACCVH010000195 DACCVH010000000
VERSION     DACCVH010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.204"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            25..>1099
                     /locus_tag="IVV98_002922"
     CDS             25..>1099
                     /locus_tag="IVV98_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001891778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7808495.1"
                     /translation="MKSSNEIEKALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIE
                     EKIIQYDGLAKLKDAKVVSGEQRINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTI
                     KEGKNIEENDKNSIIVHEEFAKQNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSG
                     KKQETYTGLSSDFSENMVFVDYSTSQEILNNSENNEIANKILMYSGSAESTDLALNKL
                     KELKIDESKYFVEKDSNAFEESLESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRE
                     RIYEIGIFLSIGTSKIQIIMQFIFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDS
                     MISGGSLINNSSFMSNITTLGQSY"
BASE COUNT          461 a           95 c          178 g          365 t
ORIGIN      
        1 tgcttgtatt cttgtttaac aataatgaaa tcaagcaatg aaatagaaaa ggctttatat
       61 gaaagttcta attcttcaat atcaataaca aaaaaagatg gtaaatattt taatgttaat
      121 caatttaaag atattgaaaa attaaaagaa attgaagaaa aaataattca atatgatgga
      181 ttagcaaaac taaaagatgc taaagtagtt agcggagaac aaagaataaa tagagaagat
      241 ttatctgacg aatttaagaa tgttgtttca ctcgaagcta caaataatac taaaagaaat
      301 attttattta gtagtggagt atttacaatt aaagaaggta aaaatataga agaaaatgat
      361 aagaattcaa ttattgttca tgaagaattt gctaaacaaa acaatctaaa attaggtgat
      421 gaagttgatc ttgaattact agatattgaa aaaagtggaa aaataaaaag tcataaattt
      481 aaaattatag ggatcttttc tggtaaaaaa caggaaacat atacaggatt atcttctgat
      541 tttagtgaaa atatggtgtt tgtagattat tcaacaagcc aagagatatt aaataattca
      601 gaaaataatg aaattgcaaa taaaatttta atgtattctg gtagtgcaga atctacagac
      661 ttagccttaa acaaattgaa agagcttaaa attgatgagt caaagtattt tgttgaaaaa
      721 gattctaatg cgtttgaaga gtctttagag tcagtgagtg gaataaaata tataataaaa
      781 gtaatgactt attctattat gttaggtggg atggttgttc tttcattaat cttgattcta
      841 tggttaaggg aaagaattta tgaaataggt atattcttat ctattggaac atctaagata
      901 caaattataa tgcaatttat attcgagtta atattcatat cgataccaag tataatatct
      961 tccttatttt taggaaatgt attactaaaa gtaattgtag atggattcat taactcagag
     1021 gattcaatga tttccggtgg aagtttaata aataatagta gttttatgtc aaatataaca
     1081 acacttggac aaagttatt
//
LOCUS       DACCVH010000196         1098 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.205, whole genome shotgun sequence.
ACCESSION   DACCVH010000196 DACCVH010000000
VERSION     DACCVH010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.205"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            269..>1098
                     /locus_tag="IVV98_002923"
     CDS             269..>1098
                     /locus_tag="IVV98_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7808496.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          387 a          152 c          187 g          372 t
ORIGIN      
        1 gtagtataat ttaaaggtaa taagttattc ttttattact atgtttgggt tttatagcaa
       61 agaaagttta ataagagttt ggacctagca aacaatatta atgaggtcat taaatcttat
      121 tatctttagt gatataacga aatatctaca cagacaaaat gatagcgtaa aatattttgt
      181 gtaaatagat atttagggta gaaaaaaaga aagtccattc tgtaaaatta aagttaccac
      241 aaccgaaatt ttataggagg actttctcat gcccaatttt actacagaaa ttatggaaac
      301 actaatcaat aaaggtgatt tagatgaatt atttcgatgt catttagaat tagctgttaa
      361 ttcattattg caggctgaat taacagcttt tcttgattat gaaaaatatg atcgtgctgg
      421 gttcaattca ggtaattccc gtaatgggaa ttattcacgt tcattcagaa cagagtatgg
      481 agaattaaat ttggtaattc ctagagatag aaatggtaag ttttctcaac aaactttacc
      541 tgcttataaa agaaccaatg actctttaga aaccactatt attcagctat ttcaaaaagg
      601 aattactatg tctgaaatct ctgaattgat tgaaaaaatg tacgggcatc actatacgcc
      661 acaaaccatt tcaaatatga ctaaaatagt ttctgaagat attattgcct ttaaagaaag
      721 gtccttagaa tccagatact ctgtcatttt tatggatgct actcacattc ctttaaaaag
      781 acaaactgtt tcaaaagaag cagtttatat tgtaattggc attcgattag atggaaccaa
      841 agaggttctt gggtttagtc ttgctccaac tgaatctgct tatgtttgga aagagattct
      901 tcaagaccta aaagaccgtg gtttaaaaga ggttttatta gtcgtaactg atggtttaag
      961 tggcattaac gatagtattc atagtgttta tccaaatgct caatttcaac aatgttgtgt
     1021 ccatatatct agaaatatcg ctcataaggt tcgtgttagt gatcgacaag aaatctgtag
     1081 cgatttcaaa ttagttta
//
LOCUS       DACCVH010000197         1069 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.206, whole genome shotgun sequence.
ACCESSION   DACCVH010000197 DACCVH010000000
VERSION     DACCVH010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.206"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..969
                     /locus_tag="IVV98_002924"
     CDS             <1..969
                     /locus_tag="IVV98_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7808497.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DACCVH010000198         1061 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.207, whole genome shotgun sequence.
ACCESSION   DACCVH010000198 DACCVH010000000
VERSION     DACCVH010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.207"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            114..1061
                     /locus_tag="IVV98_002925"
     CDS             114..1061
                     /locus_tag="IVV98_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7808498.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
BASE COUNT          355 a          161 c          241 g          304 t
ORIGIN      
        1 actcatgacg atagaggatt ttccgttttt tattttgggc tataataaac tctgttagga
       61 aaatttggta taattgatag taagaatgac aacatgttag aaaggaagag agcatgccca
      121 ctttagcaga tgttgcaaaa cgtgccaatg tttcaaaaat gacggtctct cgagtcatca
      181 atcatccgga acaggtgact gacgaattga aagagttagt tttctcagca atggctgaac
      241 tggattaccg tccaaatatt gctgcaaaag cacttgtcac gaatcggtcg cagatcatca
      301 aattatttat actggaagaa atcgacacaa ctgagcccta ttacatgaat ttgctgatgg
      361 gaatcgctaa acggatcggt aaagcgcatt attctctcca attagttaca aatgatgcct
      421 tcgacgtcgg ttcttgtgat ggatacatca tcacaggtgt cagaaaaaaa gacttcgatt
      481 ggatcgaccg tttggaaaaa ccagttgtct tgtttgggga aaattctgaa ggatatgatt
      541 atgtagacag cgataatgaa tatggtacag caaaagcaac gcaatatgcc ttagaaagag
      601 attatcaaac gattatttat atcggtatcg aagtggacga gccttttgaa atttcaaggg
      661 aaactggtta tttatctgtg atgaaggaag ttgatcttcc tagtaaaatc ttgcggtttc
      721 caaatcattc gacagaagta gaaagatata tgacagaaaa ctgggcagat tttacagata
      781 aaacttgttt tgtatgtagt tcagatcggc tagcactagg agcagtaaga gggattataa
      841 atgctggagg acacttgccc gaagaatttg gtgtgattgg atttgatggg gtatttttag
      901 accaaatcag ttcacctaaa ttgacaacga tcaagcaaga tattatacgt atgggtgaag
      961 tatgtggaga aatgttgtta aaaaaaatag aagaaaaagg ggcgagtcaa ggttatcgtc
     1021 gtttttttcc tgaactagtt atcagagaga caacgaatta a
//
LOCUS       DACCVH010000199         1060 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.208, whole genome shotgun sequence.
ACCESSION   DACCVH010000199 DACCVH010000000
VERSION     DACCVH010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.208"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(38..994)
                     /locus_tag="IVV98_002926"
     CDS             complement(38..994)
                     /locus_tag="IVV98_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808499.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt
//
LOCUS       DACCVH010000200         1045 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.209, whole genome shotgun sequence.
ACCESSION   DACCVH010000200 DACCVH010000000
VERSION     DACCVH010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.209"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            6..980
                     /locus_tag="IVV98_002927"
     CDS             6..980
                     /locus_tag="IVV98_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP7808500.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DACCVH010000201         1035 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.210, whole genome shotgun sequence.
ACCESSION   DACCVH010000201 DACCVH010000000
VERSION     DACCVH010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.210"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>1035)
                     /locus_tag="IVV98_002928"
     rRNA            complement(<1..>1035)
                     /locus_tag="IVV98_002928"
                     /product="16S ribosomal RNA"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DACCVH010000202         1027 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.211, whole genome shotgun sequence.
ACCESSION   DACCVH010000202 DACCVH010000000
VERSION     DACCVH010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.211"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(71..301)
                     /locus_tag="IVV98_002929"
     CDS             complement(71..301)
                     /locus_tag="IVV98_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808501.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(551..751)
                     /locus_tag="IVV98_002930"
     CDS             complement(551..751)
                     /locus_tag="IVV98_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7808502.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          361 a          163 c          155 g          348 t
ORIGIN      
        1 aaatctttga caaatctatt cgaaggatca aatttaaacc ataattgcgt ctcattaaaa
       61 agcataacca ttactccgat ctatttttaa acttagtctc tacctctaat atatatcgag
      121 tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt tgtttatttt
      181 cggaaaaagc taatatagct aaaattgaaa catccatctg gaatttgtct ttttcgttgc
      241 tttgctcata aaaatctgca tattcatcac taatattttt tctaataaat tcttccatca
      301 taaagatcac ctcgaaaaga gtatacgaac aaacgttctt tttgtaaagg tggaatttat
      361 tatactaaat aaataggtga acaagtactt gtgccaaatt atgtgccaaa aaaaatcgaa
      421 tttaataaaa cacaaacaaa aagaaatcct attatgataa catttcttat aataacaaac
      481 acaacagaag acgtgtaata gttagtcagg aacgtacaaa taacccctgt atcctttgcg
      541 gtacaggggg ttattttgta taagtagaca ttgtagtttc taaactgcta tgtcctaaac
      601 gtttcgatac gctaagtata tttactcctt gataaagtaa aatagatgca tgcgtatgtc
      661 ttagtccatc aataaacagt cgaagagaaa atagggaaaa attgattact aaagaaaaac
      721 ttactaggtc gacggtgtag ttgattttca tacttcaata gattcgaatt aaacgatttc
      781 gattggctta taccagtcct atccaacgaa agatatatcg ttcttaactc tagcggtata
      841 acttgaagct ttacgtaaag ccaatgggaa tgaactggag atgacttttt attattttta
      901 gtaatagctg atgggttaat acttacaact ttccttttca aagtaccata taaaaaaacg
      961 gtggggttgt ttagcgaaat aaaggatcta agccaatagc ttagatcctt tattctatgc
     1021 tttatat
//
LOCUS       DACCVH010000203         1000 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.212, whole genome shotgun sequence.
ACCESSION   DACCVH010000203 DACCVH010000000
VERSION     DACCVH010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.212"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            369..1000
                     /locus_tag="IVV98_002931"
                     /pseudo
     CDS             369..1000
                     /locus_tag="IVV98_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DACCVH010000204          985 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.213, whole genome shotgun sequence.
ACCESSION   DACCVH010000204 DACCVH010000000
VERSION     DACCVH010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.213"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>985
                     /locus_tag="IVV98_002932"
     CDS             <1..>985
                     /locus_tag="IVV98_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP7808503.1"
                     /translation="EPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITDS
                     EYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQLD
                     DTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTGK
                     KNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVGS
                     IAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFYE
                     NFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          262 t
ORIGIN      
        1 tagaaccagg cgattttatc atgagtggcg ctggaacaat tgggagaatt tcaagagtac
       61 caaagcaaat aaaaccgggt gtattcaatc aggctttgat tagacttaga ataaataaag
      121 aaatcacaga ttcagaatat tttattcaat ttattcgtgc agattttatg caaagaaaac
      181 tcacaggagc taatccaggt tcagcaatta caaatctcgt accaatgtca gaagtgaaaa
      241 aatggatagt acaatttcca atattagaag aacaaaagaa aattgggaac ttcttcaaac
      301 aactggacga cactatcgct cttcaacaac gtaagctaga tttattaaag gaaacgaaaa
      361 aaggattctt acaaaaaatg ttccctaaaa acggagcaaa agtgccagaa attcggtttc
      421 ctggatttac ggaagattgg gaacagcgta agttcaaaga gtttagtaag aagactggaa
      481 aaaagaacac gaaagattta gacttccctg cctattcggt aagtaataaa gcaggtttaa
      541 tttctcaaac agaacagttt gatggtagta ggttggatga tttagaaaaa acaaattata
      601 aattcgttga accaaatgaa ttcgcctata atccagcaag agtaaacgta ggatcaattg
      661 catttaacaa tcttggtatg acggtcattg ttagctctct ttatgtagtt gtgaaaatga
      721 gcgaggactt agataatgag ttcatacttc agtttatcaa gtcaccaaca tttatcaaag
      781 aggtcaagcg caacactgaa ggaagcgtac gagaatactt attctatgag aatttcgcta
      841 atatcaagtt tccttttact aggaataaag aggaacaaca aaaaatcggc gctttcttca
      901 aacaactcga cgacacgatc gctcttcatc aacgtaagtt agatttgctg aaggaaacga
      961 aaaaaggctt cttacaaaag atgtt
//
LOCUS       DACCVH010000205          980 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.214, whole genome shotgun sequence.
ACCESSION   DACCVH010000205 DACCVH010000000
VERSION     DACCVH010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.214"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            98..838
                     /locus_tag="IVV98_002933"
     CDS             98..838
                     /locus_tag="IVV98_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808504.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT          355 a          177 c          193 g          255 t
ORIGIN      
        1 atcgctattt tcttaaaata atcagcgcat tgctactgaa aacaatgaat ctgtgctatt
       61 attgagaaaa gttccatttt tgagaaggat ggtttgaatg aaagaaatca gacgaaaaca
      121 tttccgtttt cctgcgtacg atgatgagtt aggcgtaaaa ttaaccaacg acaagaagcg
      181 agtattattt gacggacaag aagatctttt gactgaacag aatcagtccc cgtttgaaca
      241 gatgaaagaa tttcatttca cgaacacgaa caccgagaaa atccgtcgca agcgtcgtgc
      301 aacaaatgga ttgaagtcag ctccgcgtaa ggaaaatttg gaaaagcata aaggaaaatt
      361 accggattat accggccatt accaatcaga aatcacatcg acaggacgaa aaaaactttt
      421 tggtgattcc tctcgttctg tcagacaaag tgaaacaagg acagagtcca agcatactac
      481 acgaaacgca tctgttgaca cgaaggtgcg ggagcgttct tattttgttc ctaaatatgt
      541 acccgcatcg attatcccag accctagaga aagcaaaatt tctgaggatc atttaatcga
      601 atcgatgaaa aaaacggatg actcttatct gttgttcgat acagaaccga cgccgtatca
      661 agaaaaaaga aatggtgagc cgtctgtacg aacattcaat cgaacaaaaa cgttagagga
      721 aacaaagcag tcagaagaaa aaaaatcgaa aaaaagccat ggtatcttag aacgctcatt
      781 acaaggattg atcgatgatc aaggaaactc tttgggagaa aatagctatt ttaaataagt
      841 gatatacaaa tttatattcg gctacagttg gaaaggaaac gctgcggcgt ttccttattt
      901 tatactctat ccgaaagttt atatcgtatc ctcaaatttt tttgagttta agcgaatttt
      961 ttctcccaat aagtaagaaa
//
LOCUS       DACCVH010000206          979 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.215, whole genome shotgun sequence.
ACCESSION   DACCVH010000206 DACCVH010000000
VERSION     DACCVH010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.215"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            2..>979
                     /locus_tag="IVV98_002934"
     rRNA            2..>979
                     /locus_tag="IVV98_002934"
                     /product="23S ribosomal RNA"
BASE COUNT          304 a          194 c          283 g          198 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgc
//
LOCUS       DACCVH010000207          852 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.216, whole genome shotgun sequence.
ACCESSION   DACCVH010000207 DACCVH010000000
VERSION     DACCVH010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.216"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..116
                     /locus_tag="IVV98_002935"
     CDS             <1..116
                     /locus_tag="IVV98_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP7808505.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="IVV98_002936"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="IVV98_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP7808506.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          218 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca ag
//
LOCUS       DACCVH010000208          849 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.217, whole genome shotgun sequence.
ACCESSION   DACCVH010000208 DACCVH010000000
VERSION     DACCVH010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.217"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..720
                     /locus_tag="IVV98_002937"
     CDS             <1..720
                     /locus_tag="IVV98_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP7808507.1"
                     /translation="GKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFT
                     NRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVY
                     LANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITL
                     EEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNK
                     VQLIRLNKYRVLAGNQELNLI"
BASE COUNT          326 a          133 c          167 g          223 t
ORIGIN      
        1 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
       61 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
      121 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
      181 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
      241 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
      301 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
      361 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
      421 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
      481 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
      541 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
      601 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
      661 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
      721 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
      781 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag gaacttacct
      841 atccatata
//
LOCUS       DACCVH010000209          843 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.218, whole genome shotgun sequence.
ACCESSION   DACCVH010000209 DACCVH010000000
VERSION     DACCVH010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.218"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(522..836)
                     /locus_tag="IVV98_002938"
     CDS             complement(522..836)
                     /locus_tag="IVV98_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808508.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          320 a          120 c          124 g          279 t
ORIGIN      
        1 ccagtagaat gcgtggcaac aaacctgtta tcgcatatct tggagtgtga ctatttatga
       61 gtgatagtga agatatgcgt ctccatatat gtatggttga gacagataaa catgtatgaa
      121 aaacgttgtt aaatcaacgt ttttttattt tggtcaagga gagaaaagta gagaaataca
      181 aaattttttg cattgatttt gcattcaaaa aaacattcaa acatttagaa atccccaata
      241 cgtattcagg aaaatctatt ttaaggttta caaaaagaac ttttgttcgt acactctttt
      301 tgaggtgaac ttttatgctg atggaaggaa aaacacaatt atggtttaag catgttcctt
      361 caaataagtt ttttaattat aaactctaga gaaattaatt catcctaaca taaaataatt
      421 gttcactcaa aagtttttct agaacaatta aaacagcagg cttcacattc gctatacatt
      481 tgtaagaagt aataattcct gtactaaaag gcataattgc tttaattatt ttttgacttc
      541 tcttcaaaca caagaagtag ttgtgtaata attgcagaaa taaggattcc aataatagat
      601 ataaaatttg acatggaaac gtctataaca ttaaaagaat aaagtgttga agaaagtaaa
      661 ctgattgaaa taacccctcc gtaaaaaata gtctgtgaat atacccactt tttttcagaa
      721 gacgtacttc gtttggttct aaaacctatc cctgcatttc tactcttatc aaaaaaccaa
      781 atatttagaa gtaataatat tgctattatt aagataaaat tactgtaaaa atccaaaagc
      841 tat
//
LOCUS       DACCVH010000210          842 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.219, whole genome shotgun sequence.
ACCESSION   DACCVH010000210 DACCVH010000000
VERSION     DACCVH010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.219"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>842
                     /locus_tag="IVV98_002939"
     CDS             <1..>842
                     /locus_tag="IVV98_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAP7808509.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLK"
BASE COUNT          367 a          108 c          136 g          231 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 tt
//
LOCUS       DACCVH010000211          766 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.221, whole genome shotgun sequence.
ACCESSION   DACCVH010000211 DACCVH010000000
VERSION     DACCVH010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.221"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..237)
                     /locus_tag="IVV98_002940"
     CDS             complement(<1..237)
                     /locus_tag="IVV98_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HAP7808510.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISF"
     gene            complement(230..>766)
                     /locus_tag="IVV98_002941"
     CDS             complement(230..>766)
                     /locus_tag="IVV98_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7808511.1"
                     /translation="HDYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHG
                     SQWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGP
                     DLPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSD
                     KLLNRIDKEILKVGNIDE"
BASE COUNT          269 a          124 c           89 g          284 t
ORIGIN      
        1 aaaactaatc attgctccaa tcagtagcca agaaaaacgc attttaaaaa aatttttctt
       61 tataaaaacc tcatacaaaa ctataattcc accccaagca aaagctattt tcatcgggat
      121 attagttaca ttaaaagtac taggcataaa ataaagcaga caaatgatta aatttattac
      181 tcgaaacgca tctcgactta ataaactctt ctctaaaaca ggtactattc tattcatcta
      241 tatttccaac tttcaaaatt tctttatcaa ttctatttaa tagtttatca gagtaatccg
      301 atttaacttt tcttacaaat aatttttcac tttcttttat ttgatctata tccctttcat
      361 caaaccattt gttcatggaa ggatcaataa tatgaatatt tgctaatttc gaagtttgta
      421 aagtagtttc ttcaatattt ttcaattcaa gtggtaaatc tggtcctcca ataacatttt
      481 tatttttgaa cgaggaatta aaaaaaagtg tatgaaaaaa tttttcatct ggggcaaaca
      541 tacctatttt aaaattcagg tagtcttgtt gattttgttc atacatttgt attaattctg
      601 ttaggcattc tttcgacaaa gcccaccatt gagaaccatg atacaaatca aatttatggt
      661 gtctaatttt tgggggaagt ttaatcatcc tcagacaacg attaattata gctctaaaaa
      721 ttttaaatgc agttgtgtta ttcctattaa ttctaggata atcatg
//
LOCUS       DACCVH010000212          625 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.222, whole genome shotgun sequence.
ACCESSION   DACCVH010000212 DACCVH010000000
VERSION     DACCVH010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.222"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            1..625
                     /locus_tag="IVV98_002942"
                     /pseudo
     CDS             1..625
                     /locus_tag="IVV98_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DACCVH010000213          573 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.223, whole genome shotgun sequence.
ACCESSION   DACCVH010000213 DACCVH010000000
VERSION     DACCVH010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.223"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            77..>573
                     /locus_tag="IVV98_002943"
     CDS             77..>573
                     /locus_tag="IVV98_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP7808512.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          214 a          106 c           93 g          160 t
ORIGIN      
        1 aatccataca aaaaaggaag tcccttctgt agaataaagt taacgacaac caattcacag
       61 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
      121 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      181 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      241 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      301 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      361 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      421 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      481 caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga
      541 taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DACCVH010000214          554 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.224, whole genome shotgun sequence.
ACCESSION   DACCVH010000214 DACCVH010000000
VERSION     DACCVH010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.224"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            23..>554
                     /locus_tag="IVV98_002944"
     CDS             23..>554
                     /locus_tag="IVV98_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7808513.1"
                     /translation="MEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNI
                     GKYKERDIYINECIEIVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEI
                     LANQKKITVNNYILDENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIE
                     NSYGNNKISNMDKIFDV"
BASE COUNT          248 a           42 c           79 g          185 t
ORIGIN      
        1 tttattaaga acaattgacg atttggaatt taaaaataaa gaaattttaa aattagaaaa
       61 gttaaaatat gactttttta aaggtgcatc ccatgaactt aaaacccctc ttgctagtct
      121 taaaataata ctggaaaaca tgaaatacaa tattggaaaa tataaagaaa gagatattta
      181 tattaatgaa tgtattgaaa tcgttgatag tttaacaaaa aatatttctc aaatattatc
      241 agttcattct atagaaaatt tgaataatga tgaagaatat ttgaaaataa atgatacatt
      301 agaagacata ttaaaaaagt atgaaatatt agcaaatcaa aagaaaataa ctgtcaataa
      361 ttatatatta gacgagaatg tttatatagg aaaaacagct ttaaagatta ttctatctaa
      421 tttgattagt aatgcggtaa aatatactga tgtaaatggg gtaattaata ttgggatagt
      481 taatgattgg ttatatatag agaattcata cggtaacaat aaaatttcga atatggataa
      541 aatatttgat gtta
//
LOCUS       DACCVH010000215          534 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.225, whole genome shotgun sequence.
ACCESSION   DACCVH010000215 DACCVH010000000
VERSION     DACCVH010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.225"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>534
                     /locus_tag="IVV98_002945"
     CDS             <1..>534
                     /locus_tag="IVV98_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP7808514.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DACCVH010000216          487 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.226, whole genome shotgun sequence.
ACCESSION   DACCVH010000216 DACCVH010000000
VERSION     DACCVH010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.226"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>487)
                     /locus_tag="IVV98_002946"
     CDS             complement(<1..>487)
                     /locus_tag="IVV98_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HAP7808515.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DACCVH010000217          484 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.227, whole genome shotgun sequence.
ACCESSION   DACCVH010000217 DACCVH010000000
VERSION     DACCVH010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.227"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(296..>484)
                     /locus_tag="IVV98_002947"
     CDS             complement(296..>484)
                     /locus_tag="IVV98_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808516.1"
                     /translation="ADLYLKDTGVLIGTNSKVYQEVKEKIEAKLNPSNRNRPKNHQKE
                     TSQTVTSRNFDPTNFLKR"
BASE COUNT          163 a           80 c           77 g          164 t
ORIGIN      
        1 aatcctgcat tacgagaact aaaaaaatac ttcaatgatc ttaaagtcac aaaaataaaa
       61 gcaaaaaagg gcaataaaat cgccaaatta gaatttactt tttcaagcct aacgtcagat
      121 ttgccaaaga tttctctgcg taactggtta gaagaataaa taaaaaagaa ctcgcccccc
      181 ttacattaag caagtagaca agtcccttac aaccgactaa gattgctagt acattctagc
      241 atattgtatg gggcttctaa ataaaaaaca gataggaata actcctatct gttttttatc
      301 gttttagaaa atttgttggg tcgaaatttc tagaagtgac tgtttgactg gtttcttttt
      361 gatgattctt tggtcgattt cgatttgatg gatttagttt agcttcgatt ttttctttca
      421 cttcttgata tactttagaa tttgtgccaa taagaacgcc tgtatctttt agatataaat
      481 cagc
//
LOCUS       DACCVH010000218          480 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.228, whole genome shotgun sequence.
ACCESSION   DACCVH010000218 DACCVH010000000
VERSION     DACCVH010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.228"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>480
                     /locus_tag="IVV98_002948"
     CDS             <1..>480
                     /locus_tag="IVV98_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP7808517.1"
                     /translation="VIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLS
                     SNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTK
                     KSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          158 a           87 c           86 g          149 t
ORIGIN      
        1 cagtgattat tgcttgtgtt atatggggca taattaatgg ctatactagc caaagagcca
       61 cgtatagagc ggtttgttcc gtcttatttc ctaatggtga ctttcctagt aggagtcgat
      121 tcactcgctt aagttcaaac ttagcttaca ctatcaagat tattcgatac tttttcatca
      181 agaagctcac caaaggtgaa ctagtcggaa ttatagatag ttttcctagt ccattatgta
      241 aaccagttag aaatagacaa gcaaaactat tgaatcaaat agccaaagtt ggctataact
      301 caacaaaaaa atcttatttt tatggtctta aaattcatat gatcgttact aagactggct
      361 ttccgattac ttactcaatc acgaatccag gtgtccatga cgtgaaagtg ttagagactt
      421 tatcggaaga agcgaatctt cccaatatcc taggggacaa aggatatatt agccataaaa
//
LOCUS       DACCVH010000219          478 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.229, whole genome shotgun sequence.
ACCESSION   DACCVH010000219 DACCVH010000000
VERSION     DACCVH010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.229"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(71..>478)
                     /locus_tag="IVV98_002949"
     CDS             complement(71..>478)
                     /locus_tag="IVV98_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP7808518.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          150 a           96 c           72 g          160 t
ORIGIN      
        1 cacgacctaa agatcgtgtc taattatgac tgtatcagaa aatatgatac caaacggatc
       61 tattcattaa ttaattgaca tagtttatct gttgctcttt tatgactgga taactgacca
      121 attcatgacg atccaagtct tctttattca tatttacagc agtaatttga ctgtcttcat
      181 acgtacgata ataataaatc cctttatcaa cgttacagca agaagaataa atcgtatatt
      241 cgtattttcc ttctccagta tcgcatactc ctttttgttg ctcgactgag cctagtatat
      301 gaaaaaattg actgatactt tcagattctg aatcacctga tgcagcattc attttagtaa
      361 atgtggcttt tacaaatcga gaaacagaag agagatctcc aggtaagccc aatcctccca
      421 tcccacgact ataaacattc aagctgatct ggtttgaaaa atgattttct ggtgttcc
//
LOCUS       DACCVH010000220          478 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.230, whole genome shotgun sequence.
ACCESSION   DACCVH010000220 DACCVH010000000
VERSION     DACCVH010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.230"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          153 a           64 c           67 g          194 t
ORIGIN      
        1 tttttcttga tgtgatatcc ttgtcttttt tgtaatgttt ttaacttatt gcttttgcaa
       61 aatttattta cctgttttct ggatcaacga tagtgtacat tatgctatcc ttgtttggat
      121 tttaggacgt ttaaagaggc acttttttac ataacttaat ccatagacct tttaagcatg
      181 ctgtgagata ataataaaga agagtttaaa gcgcacccca aaccacttcc ccataagtgt
      241 attacgcttt aaactctttt atatttgaat tcactaagaa gcataccata tttttgaaaa
      301 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      361 aggactgata ctatagatta caaatagtat cgtatttcgc aatcttaaaa ttatcttctt
      421 actgtgaata agataataaa atttgtattt gtccttttta ggtaacttat tttaatct
//
LOCUS       DACCVH010000221          475 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.231, whole genome shotgun sequence.
ACCESSION   DACCVH010000221 DACCVH010000000
VERSION     DACCVH010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.231"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..318
                     /locus_tag="IVV98_002950"
     CDS             <1..318
                     /locus_tag="IVV98_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7808519.1"
                     /translation="ANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYS
                     TNLIEGFNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLE
                     SMF"
BASE COUNT          189 a           70 c           63 g          153 t
ORIGIN      
        1 gcaaataatc aaataaggtt tatgatagat aaatggaaaa agcagtatcc acgagtggtt
       61 aaattgctca tgaatcctgc tatattaacc ttttataatt tccctccgtc aatcagaaga
      121 actatttatt caactaattt gattgaaggt tttaacaaac aattaaagaa atataccaaa
      181 agaaaagagc aatttcctaa tgaagaatct ctggagagat ttctagtatc tcaattcaac
      241 aactataatc aaaagtttct atgccgagtt cataaaggtt ttaaagaaat acatgataca
      301 ttagaatcaa tgttttaact tgatcaacag aatgggcttt tccatttaca cataattatt
      361 gacacaacct attctggaaa cttacaaata aaagcttatt cttcagccac cttcgggtgg
      421 ttatttttta taaaaaaatg taaaaaaata ttgatacata aataaattag ttgta
//
LOCUS       DACCVH010000222          462 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.232, whole genome shotgun sequence.
ACCESSION   DACCVH010000222 DACCVH010000000
VERSION     DACCVH010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.232"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..430)
                     /locus_tag="IVV98_002951"
     CDS             complement(<1..430)
                     /locus_tag="IVV98_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7808520.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DACCVH010000223          437 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.233, whole genome shotgun sequence.
ACCESSION   DACCVH010000223 DACCVH010000000
VERSION     DACCVH010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.233"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>437
                     /locus_tag="IVV98_002952"
     CDS             <1..>437
                     /locus_tag="IVV98_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7808521.1"
                     /translation="PIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGLQLSRRRI
                     GRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDLTYVRVGK
                     KWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDV"
BASE COUNT          136 a           82 c          105 g          114 t
ORIGIN      
        1 ccgatcgaaa atgagtccga cttagaagag atcgttcagg aagagtttat tcgaaaccga
       61 aaggcttacg gtacccgaaa attgaagaag tgtttagcaa agcgtgggct tcaactcagt
      121 cggcgccgaa tcggtcgaat catgaaacgc cgcggattga catctaccta tacgatcgct
      181 cattttaaag ggcaacgaac agcttgtaat gaagcgaaaa cagcgaatgt attagatcgg
      241 acctttacac aagaacagcc attggaagcc atcgttacgg atcttactta tgttcgcgtg
      301 gggaaaaagt ggcattatat ctgcttaata cttgatttgt ttaatcgaga aattattggt
      361 tattcctgtg gtgagaagaa agatgcctca ttggtaaaag aagcctttgg acggataccg
      421 tattctttaa cagacgt
//
LOCUS       DACCVH010000224          411 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.234, whole genome shotgun sequence.
ACCESSION   DACCVH010000224 DACCVH010000000
VERSION     DACCVH010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.234"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..390
                     /locus_tag="IVV98_002953"
     CDS             <1..390
                     /locus_tag="IVV98_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7808522.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          159 a           74 c           65 g          113 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga c
//
LOCUS       DACCVH010000225          404 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.235, whole genome shotgun sequence.
ACCESSION   DACCVH010000225 DACCVH010000000
VERSION     DACCVH010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.235"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>404
                     /locus_tag="IVV98_002954"
     CDS             <1..>404
                     /locus_tag="IVV98_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808523.1"
                     /translation="PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDK
                     SDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVV
                     VTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          166 a           60 c           92 g           86 t
ORIGIN      
        1 ccagaagata aacttccagt gttgaaagca aaagatggtt atacagatgc gaaatggcca
       61 gaggaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
      121 ctggatgata aatctgacgc tgacaaatat aatcctgaag gtcaaaaagt gactacagaa
      181 ttgaataagg aaccagacgc atttgaggga attaagaaca aagaagattt accaaaagat
      241 actaagtata cttggaaaga aaaagtagat gttagcgcag ctggaaataa aaaagggact
      301 gttgtagtga catatccaga tggatcatct gatgaagttg aagtagatgt tacagtgaca
      361 gacaatcgtt ctgacgccga taaatatgag ccaacagtag aagg
//
LOCUS       DACCVH010000226          396 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.236, whole genome shotgun sequence.
ACCESSION   DACCVH010000226 DACCVH010000000
VERSION     DACCVH010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.236"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(91..>396)
                     /locus_tag="IVV98_002955"
     CDS             complement(91..>396)
                     /locus_tag="IVV98_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808524.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          107 a           95 c           78 g          116 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggt
//
LOCUS       DACCVH010000227          321 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.237, whole genome shotgun sequence.
ACCESSION   DACCVH010000227 DACCVH010000000
VERSION     DACCVH010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.237"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>321)
                     /locus_tag="IVV98_002956"
     CDS             complement(<1..>321)
                     /locus_tag="IVV98_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808525.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DACCVH010000228          302 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.238, whole genome shotgun sequence.
ACCESSION   DACCVH010000228 DACCVH010000000
VERSION     DACCVH010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.238"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(64..>302)
                     /locus_tag="IVV98_002957"
     CDS             complement(64..>302)
                     /locus_tag="IVV98_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808526.1"
                     /translation="FYKVWDSEVFFLAIEDSLLINLYYSNKNYFKIPATKTRMKKDVY
                     FLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
BASE COUNT           95 a           59 c           45 g          103 t
ORIGIN      
        1 atatcccttt tataagtatg gtgataaaat ccgttccggg ctaccttttt taggtagcct
       61 actttaatct ttataccttt ctggatcaac gaaagtatac ttcaaatagt cataacgccg
      121 atgatcgctc cgtgcgtctg gcacatcagt cacgatatca aacaaaaaat acacatcttt
      181 cttcattctg gtttttgttg ccggaatttt aaagtagttc ttattagagt aatagagatt
      241 gattaataag ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa
      301 at
//
LOCUS       DACCVH010000229          299 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.239, whole genome shotgun sequence.
ACCESSION   DACCVH010000229 DACCVH010000000
VERSION     DACCVH010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.239"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>299
                     /locus_tag="IVV98_002958"
     CDS             <1..>299
                     /locus_tag="IVV98_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7808527.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DACCVH010000230          282 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.240, whole genome shotgun sequence.
ACCESSION   DACCVH010000230 DACCVH010000000
VERSION     DACCVH010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.240"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>282
                     /locus_tag="IVV98_002959"
     CDS             <1..>282
                     /locus_tag="IVV98_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAP7808528.1"
                     /translation="QSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGK
                     KGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNC"
BASE COUNT           84 a           52 c           56 g           90 t
ORIGIN      
        1 aacaatcgaa gagacttttt cctgaaatca attgtgttgt cgctgatgct gggtataaga
       61 cacctaagtt tgttcacttt ttgactcatt tgaaccttcg accttgtttg ccttattcaa
      121 ggcccaaagg gaaaaagggg ctattatcaa aaaatgagtt tctctatgac gagtattttg
      181 attgttatat ttgtccgcaa gatcaaatgc tcgctttttc aacggttact cgagaagggt
      241 accgagaata caaatccaat ccaaaagaat gtgtgaactg tc
//
LOCUS       DACCVH010000231          279 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.241, whole genome shotgun sequence.
ACCESSION   DACCVH010000231 DACCVH010000000
VERSION     DACCVH010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.241"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            1..279
                     /locus_tag="IVV98_002960"
                     /pseudo
     CDS             1..279
                     /locus_tag="IVV98_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          107 a           56 c           55 g           61 t
ORIGIN      
        1 caaatcgtcg atctctatct cgctggtaag cctcgcgcag aaattattcg agagtatgag
       61 cttacgcctt cttctttcga taaatggatg aagcaagcac aatcaacggg ctcattcaaa
      121 gaaagagaca acttaacacc agaacaagca gaattgatcg cactaagaaa gaaaaataag
      181 caactcgaaa tggagaatga tattttaaag caagcggcgc tgatattcgg acgaaaagac
      241 aagtaattga tgccaacaag cataaatatt ccatatcag
//
LOCUS       DACCVH010000232          275 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.242, whole genome shotgun sequence.
ACCESSION   DACCVH010000232 DACCVH010000000
VERSION     DACCVH010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.242"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            72..>275
                     /locus_tag="IVV98_002961"
     CDS             72..>275
                     /locus_tag="IVV98_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808529.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNED"
BASE COUNT          114 a           30 c           48 g           83 t
ORIGIN      
        1 tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt
       61 aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta
      121 aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag
      181 taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac
      241 ctcaaacagg aaaaatattg tttaagaatg aagat
//
LOCUS       DACCVH010000233          267 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.243, whole genome shotgun sequence.
ACCESSION   DACCVH010000233 DACCVH010000000
VERSION     DACCVH010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.243"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(35..>267)
                     /locus_tag="IVV98_002962"
     CDS             complement(35..>267)
                     /locus_tag="IVV98_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808530.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          103 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaata
//
LOCUS       DACCVH010000234          253 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.244, whole genome shotgun sequence.
ACCESSION   DACCVH010000234 DACCVH010000000
VERSION     DACCVH010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.244"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            28..>253
                     /locus_tag="IVV98_002963"
     CDS             28..>253
                     /locus_tag="IVV98_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP7808531.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DACCVH010000235          241 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.245, whole genome shotgun sequence.
ACCESSION   DACCVH010000235 DACCVH010000000
VERSION     DACCVH010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.245"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..220)
                     /locus_tag="IVV98_002964"
     CDS             complement(<1..220)
                     /locus_tag="IVV98_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7808532.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DACCVH010000236          233 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.246, whole genome shotgun sequence.
ACCESSION   DACCVH010000236 DACCVH010000000
VERSION     DACCVH010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.246"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DACCVH010000237          226 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.247, whole genome shotgun sequence.
ACCESSION   DACCVH010000237 DACCVH010000000
VERSION     DACCVH010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.247"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT           67 a           41 c           40 g           78 t
ORIGIN      
        1 aagtatggtg ataaaatccg ttccgggcta cctttttagg tagcctactt taatctttgt
       61 atctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga tcgcttcgag
      121 cgtctagcac atcagtcacg atatcaaaca aaaaatatac gtctttcttc attctagttt
      181 tcgcagcagg gattttaaag tagttcttat tagaatagta gagatt
//
LOCUS       DACCVH010000238          225 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.248, whole genome shotgun sequence.
ACCESSION   DACCVH010000238 DACCVH010000000
VERSION     DACCVH010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.248"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..156
                     /locus_tag="IVV98_002965"
     CDS             <1..156
                     /locus_tag="IVV98_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAP7808533.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT           95 a           16 c           53 g           61 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa cttta
//
LOCUS       DACCVH010000239          220 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.249, whole genome shotgun sequence.
ACCESSION   DACCVH010000239 DACCVH010000000
VERSION     DACCVH010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.249"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..175)
                     /locus_tag="IVV98_002966"
     rRNA            complement(<1..175)
                     /locus_tag="IVV98_002966"
                     /product="16S ribosomal RNA"
BASE COUNT           48 a           60 c           49 g           63 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc
//
LOCUS       DACCVH010000240          218 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.250, whole genome shotgun sequence.
ACCESSION   DACCVH010000240 DACCVH010000000
VERSION     DACCVH010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.250"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>218
                     /locus_tag="IVV98_002967"
     CDS             <1..>218
                     /locus_tag="IVV98_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808534.1"
                     /translation="SFIAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRS
                     HASIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT           66 a           39 c           44 g           69 t
ORIGIN      
        1 tcttttattg cgaaaaattg tcaggtatct ttgaccaccg ttattcgtac gttgaaagag
       61 tttaaaagct acttaccaaa gcaatctaag aggattctcc ccagagtatt gatggttgat
      121 gaatttcgtt cgcacgcttc catagaagat aaaatgagct ttatttgcgc agatggcgaa
      181 acaggacaat taattgatgt cttgcctacg cgtaaatt
//
LOCUS       DACCVH010000241          215 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.251, whole genome shotgun sequence.
ACCESSION   DACCVH010000241 DACCVH010000000
VERSION     DACCVH010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.251"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>215)
                     /locus_tag="IVV98_002968"
     CDS             complement(<1..>215)
                     /locus_tag="IVV98_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808535.1"
                     /translation="KQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFD
                     NAVAESTYKSLKVEFVYQYTFETLQQL"
BASE COUNT           68 a           37 c           35 g           75 t
ORIGIN      
        1 tccaattgtt gtaaggtttc aaatgtgtat tgatagacaa attctacttt caacgactta
       61 taagttgatt cagctacggc attatcaaaa ggacagcctt tatgactcaa tgatcgattg
      121 atgtcaaaag ttgttaataa ttcatcaata gcttggttat caaactcttt tccacgatca
      181 gtatgaaaaa tctcaacctc tgtcagaggt tgttt
//
LOCUS       DACCVH010000242          206 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.252, whole genome shotgun sequence.
ACCESSION   DACCVH010000242 DACCVH010000000
VERSION     DACCVH010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.252"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT           75 a           33 c           37 g           61 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctcc
//
LOCUS       DACCVH010000243          206 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.253, whole genome shotgun sequence.
ACCESSION   DACCVH010000243 DACCVH010000000
VERSION     DACCVH010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.253"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>206)
                     /locus_tag="IVV98_002969"
     CDS             complement(<1..>206)
                     /locus_tag="IVV98_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7808536.1"
                     /translation="IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLL
                     FITDGLKGMKDTIHQIYPKAKYQH"
BASE COUNT           56 a           42 c           37 g           71 t
ORIGIN      
        1 caatgctgat attttgcttt aggataaatt tgatggatag tatctttcat gccttttaag
       61 ccgtccgtaa taaaaagcaa gacttcttga actcctctgg agttaatatc ctgtagcagc
      121 tcattccaaa cgtatgttga ttcagttgga gcaatcgcat aactcagtac ttctttagtg
      181 ccgtcttctc gtataccaat ggcaat
//
LOCUS       DACCVH010000244          205 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.denovo.254, whole genome shotgun sequence.
ACCESSION   DACCVH010000244 DACCVH010000000
VERSION     DACCVH010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.denovo.254"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>205
                     /locus_tag="IVV98_002970"
     CDS             <1..>205
                     /locus_tag="IVV98_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7808537.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKL"
BASE COUNT           62 a           49 c           38 g           56 t
ORIGIN      
        1 ctagtgatgg acatgaatgc cagctattgt cagttgctta aaacagtctt tccaaatgcg
       61 gagatcgtaa ctgaccgctt tcatattgtc caacacatca atcgcagctt caatcaatta
      121 cgtgtccaga tcatgaatcg ttttcgaacc tcacactctg aaaatcagaa gaagtaccgt
      181 cggctcaagc gatattggaa actct
//
LOCUS       DACCVH010000245         9258 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.101, whole genome shotgun sequence.
ACCESSION   DACCVH010000245 DACCVH010000000
VERSION     DACCVH010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.101"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            11..310
                     /locus_tag="IVV98_002971"
     CDS             11..310
                     /locus_tag="IVV98_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7808538.1"
                     /translation="MLYLKLCNRTELYKYQAESERKRIKERQAQGIEIAKKKGKFKGR
                     QPKFKENDPRLQHAFDLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            326..1003
                     /locus_tag="IVV98_002972"
                     /pseudo
     CDS             326..1003
                     /locus_tag="IVV98_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            1515..1811
                     /locus_tag="IVV98_002973"
     CDS             1515..1811
                     /locus_tag="IVV98_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAP7808539.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            1812..2228
                     /locus_tag="IVV98_002974"
     CDS             1812..2228
                     /locus_tag="IVV98_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAP7808540.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            2248..3792
                     /locus_tag="IVV98_002975"
     CDS             2248..3792
                     /locus_tag="IVV98_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7808541.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            3935..4159
                     /locus_tag="IVV98_002976"
     CDS             3935..4159
                     /locus_tag="IVV98_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7808542.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4174..5043
                     /locus_tag="IVV98_002977"
     CDS             4174..5043
                     /locus_tag="IVV98_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAP7808543.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5024..5758
                     /locus_tag="IVV98_002978"
     CDS             5024..5758
                     /locus_tag="IVV98_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7808544.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5791..6699
                     /locus_tag="IVV98_002979"
     CDS             5791..6699
                     /locus_tag="IVV98_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAP7808545.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            6696..7238
                     /gene="sat4"
                     /locus_tag="IVV98_002980"
     CDS             6696..7238
                     /gene="sat4"
                     /locus_tag="IVV98_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAP7808546.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            7331..8125
                     /locus_tag="IVV98_002981"
                     /note="aph(3')-IIIa"
     CDS             7331..8125
                     /locus_tag="IVV98_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAP7808547.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(8233..8421)
                     /locus_tag="IVV98_002982"
                     /pseudo
     CDS             complement(8233..8421)
                     /locus_tag="IVV98_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8401..8973
                     /locus_tag="IVV98_002983"
     CDS             8401..8973
                     /locus_tag="IVV98_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7808548.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         3259 a         1477 c         2014 g         2508 t
ORIGIN      
        1 aagggatttt attctttatt taaaactttg caacagaacc gaattgtata agtaccaagc
       61 ggaatctgaa cgcaaacgaa ttaaagaacg ccaagcccaa ggaattgaaa ttgctaagaa
      121 aaaaggaaaa ttcaaagggc gacaacctaa attcaaagaa aatgatccac gtttacaaca
      181 cgctttcgat ttatttttga atggttgttc cgataaagaa gttgaagaac aaactggaat
      241 taatcgccga acgtttagaa ggtatcgatc aagatacaac gtgacagtag atcaaagaaa
      301 aaaacaatga aaagagggat agttaatgag tacggttatt ttagctgaaa aaccaagcca
      361 ggcattagcc tacgcaagtg ctttaaaaca aagcaccaaa aaagacggtt attttgagat
      421 caaagaccca ctatttacag atgaaacgtt tatcaccttt ggttttgggc atttagtcga
      481 attagcagaa ccaggtcatt ataacgaaaa gtggcagaac tggaaacttg aatctttgcc
      541 gatttttcct gatcgatacg attttgaagt tgcaaaagat aagggaaagc agtttaaaat
      601 tgttgctgaa cttctcaaaa aggcaaatac aattattgtc gcaacagata gcgacagaga
      661 aggtgaaaat atcgcctggt cgattatcca taaagcaaat gccttttcta aagataaaac
      721 gtataaaaga ttatggatca atagcttaga aaaagatgtg atccgaagcg gttttcaaaa
      781 tttgcaacca ggaatgaatt actatccctt ttatcaagaa gcgcaaacac gccaaattgc
      841 cgattggttg atcggcatga acgcaagccc tttatatacc ttgaatttac aacaaaaagg
      901 cgtacaaggt acattttcat taggacgtgt acaaacaccg actttatatc tcatttatca
      961 acgccaggaa gcaatagaaa actttaaaaa agaacctttt ttcctgaata attcatagtt
     1021 ttactaatag tctttcctaa cattgattta atagtcttta aagtattctg cttcatcacc
     1081 cattaggtga tgaaaaaaga acccctttct gatttagcgg acaaatactt tgacctaatc
     1141 tcagaagata taaaagaaaa aataataaaa tatccgattt atactttgta taaagaacta
     1201 aagtagttag caaatcattt acagcaaatc actatgttcc acataccatt ttacatactt
     1261 accttatcca cgacacatgt tgagatagta tcgaagataa agaaagttgc tccatgttgt
     1321 ttttgcgaga tggggaaatc aaagccacat tgacaaccat gatgaataag cttgctttca
     1381 gtcataagct aatcctagaa ccacttttca agtcagttag ccaaatcgat gaagaaagcg
     1441 accgtgaaag aatggacgct attgataagc taatggagca actattggaa gaacgcaata
     1501 cccttattgc actgatgtcc aaaggtttcc tagaacctgc tctttttaat caggaacgaa
     1561 atgttttaga tagtgagatt aaaaatctta ctaccgaaaa aacaaacctg gtaacgaact
     1621 ctgcgagtgg ggttttgcga gcaaacgaga taaaggacct cattaattat gtgtcagcag
     1681 ataattttaa tggtgactac acggaagaac tatttgaaga atttgtagtg aacatcattg
     1741 taaattccag ggatgagctg acattcaatt tgaaatgcgg tctttccctg aaagaaaagg
     1801 tggtgagata aatggcatat attccatatg gatacaaaat tcaagatgga gtggttactg
     1861 tcgatgaaaa ggcagcaggt caagtaaagg tattctttga gaaatacata tcaggactat
     1921 cccttacagt ggctggcgaa caggcaggta ttgaaaagac acattctgtg atggggcgca
     1981 ttttgaaaaa cgtcaactac cttggaaatg atacgtatcc agcaattatt gataaagaga
     2041 tatttgataa agctgaagaa gttagagata aacgtgcaaa ggatttagga cgagtggtag
     2101 agcttgccgc tttcacctct ccccctccca aagaacgatt caaaatgaaa aaggcagata
     2161 ataagatgcc agtggatcct tttgaacgag cagaatactt atacagtctg atagaaagcg
     2221 aggaataaag tgacagagaa aaatataatg gttattcctg ctcgtaaaag agtaggaagt
     2281 acagccgcaa aagaaaagat aaagaaactt cgtgttgctg cctattgccg tgtttctaca
     2341 gaaacagaag aacaaaattc tagctatgag gttcaggtct cacactatac agagtttata
     2401 aagaaaaata atgaatggga gtttgctggc atctttgcag atgatggtat ctctggtacg
     2461 aacactaaaa agcgtgacga atttaatcgc atgattgcag agtgtatgga cggtaacatc
     2521 gacatggtta ttacaaaatc catcagccga tttgcgcgta acaccctaga ctgccttcaa
     2581 tacattagac agctcaagga taagaacata tcagtttatt ttgagaaaga gaacatcaac
     2641 accacggatg ccaaaggtga ggttttgctg actattatgg catctttggc acagcaggaa
     2701 agccagagcc tttcacaaaa cgttaagctt gggctacagt accgatacca acaaggaaag
     2761 gtgcaggtca accataagcg atttatgggc tacacgaaag atgaagatgg aaatttaact
     2821 attgtccccg aagaagctga gattatcaaa cgcatctacc gagaatacct tgagggtcag
     2881 agtctagtgg gcattggtcg agcccttgaa aaggatggta ttttaacagc agcgggaaaa
     2941 ccaagatggc gaccagaatc agttaagaag atacttcaaa acgaaaaata catcggagat
     3001 gcccttctgc aaaagactgt cacagtagat tttctgacca agaaacgagt gaaaaatgaa
     3061 gggcatgttc cccaatatta tgttgaaaat agccatgaag cgattattcc taaagagtta
     3121 tttttgcagg cgcaagaaga aattcatcgg agaagcaata tctacacagg agaaggcaag
     3181 aacaaaagaa tttacagtag caagtacgct ttaagtgcca tcaccttctg tggagattgt
     3241 ggcgatattt atagacgggt ctattggaat atccacggaa gaaaagaatt tgtctggcga
     3301 tgcgtgacta gaatcgagca aggtcctgaa gtttgtaaga accgaaccgt aaaagaagat
     3361 gaactttatg gtgcagtaat gactgcgatt aataagctac ttgcaggtgg gaacaatatg
     3421 ataaagacac tggaagagaa tattcatgct gtgattggcg aaaccacaga ataccaaatt
     3481 tcagagatta acaactcact agaggaaaaa caaaaagaac taatcaagct ggcgaacaag
     3541 ggtcaagact atgaccactt agcagatgag attgatgagc tgagagacaa gcgacagatc
     3601 cttttagtag aagatgcctc cctcagtggc gagaacgagc gaatcaatga gctgattgaa
     3661 tttatccgca agaacaaatt ccgcacctta gaatatgatg ataagcttgt aaggaagata
     3721 atccagagcg ttacagtcta tgaaggccac ttcgtcatag ccttcaaatc tggcatcgaa
     3781 atggaaatat gaaaaccaga agtaaatagc ccatgactct acagtagagt tgtgggtttt
     3841 cttttgcttg ctgattataa taatatttta ataactattg tgtttatcaa ccaaatggtt
     3901 tataatattc ttagcgtaaa cttggaggtg ctgtatgact acggcagaaa tgattaaaga
     3961 actgtgtgag caaatgaata taagtgtttc cgaacttgct agacgtattg gccagactcc
     4021 acagaatttc aataaaaaat tacaacgaga aacagtaacc ttggatgagt tgaaggccat
     4081 tgctgatgtg ctaggtgtca agtttgtgca ggcatttatt ttaccagatg gagaagaaat
     4141 aaaaatatct aacgaataaa ggaggatgtt tatatggtag gtaatgttat tcaaatagta
     4201 acagagaaat tatcatcttt gccttttata gaaggcatcg tattaggggg ctcacgtgca
     4261 agaggcaccc atacagaaaa ttctgatata gatatcggaa tctattacaa ttcagactca
     4321 tttgacctga cagcgattaa tcaaattgct acagagttgg atgatgagaa tagaaacaac
     4381 cttgttgtac ctcccggagc gtggggtgat tgggttaatg gcggtggatg gttagttata
     4441 aacgggtgtc atgttgactt gatattacgt gatataaaac gggtggaaca aataatcaaa
     4501 gatacggagc aaggaattgt tactgccaat tatcagaccg ggcatcccca tggttatata
     4561 agtgctatgt atcgtggaga attagcgatt agtaaaatac tatatgctaa gaacgaaagc
     4621 ttatgcgaat taaaaaagca ggcagaaatt taccctactg ctctaaagaa aagcttgatg
     4681 aactttttta tatttgaagc tgaattctct ttaatgtttg taaaagcaaa tgcgggggca
     4741 gaggataaat attatattgc aggccatgtt tttcgtatta tttcatgctt aaatcaagta
     4801 ctatttgcat gtaataatgc ttattgcatt aacgaaaaga aagctataaa actgcttgaa
     4861 acttttgaat ataaacctga aaaatatgcc gaaagagtta atcatatttt tgaagtactc
     4921 ggtctttctc tttttgaatg ctacgacatg accgagaaac tttataaaga agtgaatgaa
     4981 attgtatcgg agataaataa ctttttaaac gaggagagtt cagatgaaag aaaacaaata
     5041 tgatgataat atattttttc aaaaatacag tcaaatgagt cgctcgcaga aaggactggc
     5101 tggtgcggga gaatgggaga ctttgaaaaa gatgctacct gattttaagg gtaagcgtgt
     5161 gcttgattta ggatgcggct atggatggca ctgtatatat gcgatggaaa acggtgcttc
     5221 ctctgtagta ggtgttgata tttctcataa aatgctcgaa gtagcaaaag gaaaaaccca
     5281 ttttccacag attgaatatg aatgctgtgc catagaagat gtggatttcc cagaggagag
     5341 ctttgatgta atactaagtt cgcttgcgtt tcattatgta gcagactatg agaatttaat
     5401 aaaaaagata tataggatgc tgaaggctgg tggcaattta gtttttacag ttgaacatcc
     5461 tgtttttact gctcatggaa cacaagactg gtattataac gaaaaaggag aaatactgca
     5521 tttcccggtg gacaattatt attatgaggg caaacggaca gctatgtttt tggaagaaaa
     5581 ggttacaaaa tatcatagaa cactgaccac atatctaaat acactgcttt caaatagttt
     5641 tataataaat cagattgtgg agccacagcc gccagagaac atgatggata ttccggggat
     5701 ggcggatgaa atgcgacgcc caatgatgct gattgtatcg gcaaaaaaga agatgtaata
     5761 atatagaaaa aataaacgag gagtatgtaa atgagatcag aaaaagaaat gatggattta
     5821 gtactttctt tagcagaaca ggatgaacgt attcgaattg tgacccttga ggggtcacgc
     5881 gcaaatatta atatacctaa agatgaattt caggattatg atattacata ttttgtaagt
     5941 gatatagaac cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg
     6001 atgcaaaagc cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt
     6061 atgctatttg atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat
     6121 aattacctaa agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa
     6181 agggacatag ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat
     6241 gatgattgct gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt
     6301 aaggaaattt tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga
     6361 atgatatcat ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat
     6421 aagtttattg aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg
     6481 atggattcct atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg
     6541 gtatccggtg aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata
     6601 acaaaatata ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc
     6661 acatatgccg ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc
     6721 acctgaaaga tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga
     6781 ggtatgaaaa cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa
     6841 gctaccaaga cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca
     6901 atactgataa gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac
     6961 tgcgaaaaaa ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca
     7021 gggggcaagg cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa
     7081 acttgcatgg actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc
     7141 ataattgtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
     7201 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
     7261 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
     7321 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
     7381 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
     7441 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
     7501 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
     7561 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
     7621 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
     7681 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
     7741 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
     7801 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
     7861 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
     7921 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
     7981 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
     8041 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
     8101 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
     8161 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
     8221 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
     8281 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
     8341 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
     8401 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
     8461 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
     8521 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
     8581 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
     8641 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
     8701 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
     8761 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
     8821 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa tatcaattca atatcctgca
     8881 tcaggagggc aagaaccgga aagcagaatg atagagccta tatcactggg gttttatgaa
     8941 cagaactggt acttaatcgg ttttgcaggc taagaaatga atataggaat tttcgtgtgg
     9001 atcggattaa aagcatttgc atagaagaag agctctgtca aagccatgat ggctctttgg
     9061 aacaaatatt aaaacaaatg ctttcatata aaaaactata tgccctacaa tgccgttgta
     9121 aaaattgggg aaaagggata tattgatttt atatctttct caaaataaat ataaaagccc
     9181 tttaaagagg gcttttatat attaatcaca aatcacttat cacaaatcac aagtgattaa
     9241 tcacaaatca cttgtgat
//
LOCUS       DACCVH010000246         7943 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.111, whole genome shotgun sequence.
ACCESSION   DACCVH010000246 DACCVH010000000
VERSION     DACCVH010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.111"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            128..1564
                     /locus_tag="IVV98_002984"
     CDS             128..1564
                     /locus_tag="IVV98_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7808549.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4185
                     /locus_tag="IVV98_002985"
     CDS             1753..4185
                     /locus_tag="IVV98_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP7808550.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            4415..5482
                     /gene="rlmN"
                     /locus_tag="IVV98_002986"
     CDS             4415..5482
                     /gene="rlmN"
                     /locus_tag="IVV98_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP7808551.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5675..6778)
                     /locus_tag="IVV98_002987"
     CDS             complement(5675..6778)
                     /locus_tag="IVV98_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7808552.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7330..7878
                     /gene="aac(6')"
                     /locus_tag="IVV98_002988"
     CDS             7330..7878
                     /gene="aac(6')"
                     /locus_tag="IVV98_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP7808553.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2658 a         1357 c         1724 g         2204 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaagttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaata tgagaagaaa aaagcggtga gccagcaaag ggaaaatact
     2521 gctgatgaat ggcaggaacc agaaaataca gagccggagc agctaagttt tgttccaatc
     2581 gacagttttc aagaaaatat ccatcctgcg aatctagaga aaccagtacc agatacacca
     2641 aaacagacca atacagcaga aggtttttca gatgagttgc cagaggatga cggtacctca
     2701 ttagaatttg agattgaagc agaacaggaa aatcaagact atgaattacc gacagttgat
     2761 ttgcttgatt ctataccaac tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat
     2821 atcggcgtat tagaacaaac tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc
     2881 agcttaggac catccgtcac aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt
     2941 aaaattgtga acttaacaga tgatatcgcg cttgctttag cggcgaaaga tgtccggatg
     3001 gaagcaccga ttccaggtaa atcactgatt ggtattgaag taccaaatgg aaagatcagt
     3061 atggtttcct ttagagaaat catcgaagca caaccaaacc acccagataa attactagaa
     3121 gtacctttag gacgtgatgt ttctggacgg gtacaaacgg ctgatctttc gaagatgcct
     3181 cacttactcg tggctggttc gactggtagt gggaagtcag tagcaattaa tgggattatc
     3241 acaagtatat taatgcgtgc taagccccat gaagtaaaac tgatgatgat cgatccgaaa
     3301 atggttgaat tgaatatgta caacggcata cctcatctgt tgacgccggt cgtgacgaac
     3361 cctagaaaag cagcgcaagc cttacaaaaa gtagtacaag aaatggaaga acgatatgaa
     3421 aaattcgcgg caaccggagt aagaaatatt tctggttaca atgaatttgt tcaacagaaa
     3481 aacttggaaa acggaacgaa acatccaacc ttaccattca tcgtagtgat cgtagatgaa
     3541 ttagctgatt tgatgatggt agccagcaat gaagttgaag atgcgattat tcgtttagcg
     3601 caaatggctc gggcagcggg gattcatatg atcctagcta ctcaacgtcc aagtgtggat
     3661 gttatcacag gaatcatcaa agcaaatgta ccttccagaa tggcatttgc ggtatcaagc
     3721 ggtacagatt ctcggacgat cattgattct aatggggcag aaaagctctt agggcgagga
     3781 gatatgctat tcttgccaat gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt
     3841 tctgaccacg aagtagaacg ggtcgttcaa tttgttacag atcagcaaga agctcattat
     3901 gaagagaaaa tgatgccgac agatgaagtt gaaacgacag gtgctccaga acagccacaa
     3961 gatgagctgt ttgaagaagc aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc
     4021 cttctccaaa gaagatttcg gatcggttac aaccgagcag cacgtttagt agatgaactg
     4081 gaagctcatg gagttgttgg cccgtcagaa ggaagcaagc ctcggaaagt attcattgag
     4141 caggaagaaa catcagaaac gttgccggac gataatgaca tgtaaaactt gtgtgatgaa
     4201 gggttgaaaa acgaataacc aataaaaaga caaggcatga tgataccaaa agaaaaaatg
     4261 gtttttttcc atcttttcta atacggtatg atgtcttgtc tttttagttt ttgtgagatt
     4321 aaagttctat tcgatttatt tgtgaagtat tgcattaagg aaatgaatca tgtatagtat
     4381 gtagcgaaac tttgagaaaa agagggaaaa tactttggaa aaacagtcca tttatggctt
     4441 gacgaatgaa gaattaatca attggtttat agaaaacggc gagaaaaaat tccgagctgc
     4501 ccaagtttgg gaatggttgt atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct
     4561 atcgaaacaa ttgatcgaaa aattatcgga gcattttatc atcaatcctc taaaacagat
     4621 ggtcgtccaa gaagcttcgg atggtacagt aaaatatttg tttgaactcc ctgataaaaa
     4681 catgattgag actgtactga tgagacaaga atatggcttg tcagtttgtg tgacgacaca
     4741 agtaggatgt aatatcggct gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga
     4801 tctgactgct ggagaaattg ttgcacagat catgatggtc caacattatt ttgatgagcg
     4861 caatcttggc gaacgcgttt cacatgtcgt tgtaatgggg atcggtgagc catttgataa
     4921 ttacgacaat gtaatggact ttttgcatat catcaatgat gccaaaggat tggcaattgg
     4981 tgctcggcac attacagttt ccactagtgg attagcacac aaaatcaagg aattcgctaa
     5041 taacggcttg caagtcaatc tggctatttc cttgcacgcg ccgaataatg aggtgcgaac
     5101 atcgatcatg cggatcaacc gaagtttccc aattgagaaa ttgatggaag ctgtggatga
     5161 gtatttagag aaaacaaacc gtcgaatcac gtttgaatat atcatgttga atcaagtaaa
     5221 tgatagacca gagcatgcgc aacaattagc agatctatta aaagataaga aaaaattagc
     5281 atatgtcaac ttgattccat ataatccagt cagtgaacat gatcaatatt ctcgcagtcc
     5341 aaaagctgat gtattgagat tttatgatgt attgaagaaa aacggcgtaa actgtgtgat
     5401 acgtaaagaa catggtacag atattgatgc agcttgcgga caattgcgaa gcaagcaaat
     5461 gaaaaaaaca gttgccaaat aatcgtatcc tactcgtttt ttcaattacc ataaaaggag
     5521 cagttttctt aattaaggaa ctgttcaact taaataagag aaaagattct atagcgaaag
     5581 ctataaagct ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga
     5641 tgacagcctg cttgatgggg gttttagcaa ttatttaact gattttctta tatccttgct
     5701 ggctttcttg tgtagcatga taagtttcta cgtcaagaat ggcctgttta aatttttctc
     5761 gggtgatttc ataaggcaca tgtttaatat catttgttgc catggcttta tctaagattg
     5821 cttctaaatc ggtcgtgaca ttgagattca tgtcggttaa cgatactgga agttggttct
     5881 ttttcataaa cacatagatt ttatcaaaca aatcgaactg ctgatccatc atcaataagg
     5941 tcagtacacc ataactgaca gatgctccgt gaaggtatcc ctccattttt tctagaacag
     6001 tcgtaccgta atagaatgag tgtgccatag cagaattata gttattgtta actaaaacag
     6061 aaaccaatcc ggtagtaaca atgatatccg aaacgacttg ttcaattgca tatgagggac
     6121 gatcgtcggc actatctttc aatgcttgcg taccataagt caagagacga tcaatgcaca
     6181 tttttccgat ttggattcct aatctatccg tgtagcctag atcatcgcca cgagcagaaa
     6241 aagtagattc gacttctttg gataaagcat cgccaatacc tgcccataag tatttatcag
     6301 gtgcttcggc aataattgct gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga
     6361 agagtccgtc cattacgcct tcttcgttat agatgacaca taccgcagtg acgggcgaac
     6421 agttcgaacc aatagtggga aaggtgaaga ctggtttagc tagtttttca ccaatgactt
     6481 ttacagtatc gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct ttttggacac
     6541 tttcatgctg gatcaactgt tcaatatttc cataagttga attacccccg taccagagac
     6601 tggcgacaac ctctatttcc tgtgtcaaag ctacttttat tttgttttct gcctttgaaa
     6661 gtgcagtctt ccctccaatc agcactactt ttgtcccata ttctttgacg attccatttg
     6721 ctttttcata cgcatctgtt ccaatggtat aatttggtaa gaaaacactt tgactcatat
     6781 tcatttcctt ctttcttcgt tgaaacgggt taaaatttta aagagtgatc gatctgactg
     6841 cggctgtaga tggagtagag gtgaacctaa gacaggataa gtgatgaata aggtggcatg
     6901 aacaccttga aatcatcaat aagtatccta aaaacgaaca agtacaaaaa cattgaaaac
     6961 gacaataatg aatttttgtt cctcttagta tttctaccga ttccctttgc ttttttgtaa
     7021 ttatctaaaa attctaaaaa ttaagattat tatatgaaaa caggttttat ttgtcaattc
     7081 ataattggtt ttttttaaag caaaagataa tctatatcat gatgaacaaa cagagttttt
     7141 tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt ctgtataatt
     7201 ttttatttta taagtaagat aaataatgaa agaatagaga tactgattgg tagctaaaga
     7261 tttttgagcg agaacatttc gttttttcaa aaggactgtt agaataagca agaacaaggg
     7321 ggaagacgta tgataatcag tgaatttgac cgtaataatc cagtattgaa agatcagctt
     7381 tctgatttac tgagactgac ttggccggaa gaatatggag acagctcggc agaagaagta
     7441 gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga tgagttagta
     7501 ggatttattg gtgcaatccc tcaatacggt atcacaggtt gggaattgca tccattagtt
     7561 gtagaaagct cccgacgaaa gaaccaaata ggtactcgat tagtcaatta cttagaaaaa
     7621 gaagtagctt ccagaggagg aatcacgatt tatttaggta cggatgattt agaccatgga
     7681 acaacgttaa gtcaaacgga cctgtatgag catacatttg ataaagtggc ttccatccag
     7741 aaccttcgtg aacatccgta tgaattctat gaaaaattag gttataaaat cgtaggtgtc
     7801 ttaccaaatg caaatggctg ggacaaaccg gatatttgga tggcaaaaac gattattcct
     7861 cgaccaaatt ctcaataata aaaagaggtt gtgacagaag taatcagctt caagaaataa
     7921 gaaggaattt acgaaaatta ctt
//
LOCUS       DACCVH010000247         7706 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.114, whole genome shotgun sequence.
ACCESSION   DACCVH010000247 DACCVH010000000
VERSION     DACCVH010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.114"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            39..1160
                     /locus_tag="IVV98_002989"
     CDS             39..1160
                     /locus_tag="IVV98_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7808554.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1418..2920
                     /locus_tag="IVV98_002990"
     CDS             1418..2920
                     /locus_tag="IVV98_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP7808555.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2987..3514
                     /locus_tag="IVV98_002991"
     CDS             2987..3514
                     /locus_tag="IVV98_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7808556.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3725..4786
                     /locus_tag="IVV98_002992"
     CDS             3725..4786
                     /locus_tag="IVV98_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7808557.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4789..5685
                     /gene="murQ"
                     /locus_tag="IVV98_002993"
     CDS             4789..5685
                     /gene="murQ"
                     /locus_tag="IVV98_002993"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP7808558.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            5699..7681
                     /locus_tag="IVV98_002994"
     CDS             5699..7681
                     /locus_tag="IVV98_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7808559.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
BASE COUNT         2583 a         1348 c         1758 g         2017 t
ORIGIN      
        1 aaaaagtgtc ttacttaaga agaaagtgag ggatacagat ggatattttg gcggcaattg
       61 attcatttaa aggaagtgct tcttcatttg aactaaatca ggcagttcta aatggctggg
      121 aagatcgtaa aggaagaaaa atcaatgtgc cgattgcaga tggcggagaa aatactgcag
      181 aagcaatcta ttacgcgctc aggggaacat ggcgtaccat tgatgggatg gatctcttat
      241 tccgtcagcg aaaaatcagc tatttattga caacttggca aggaaaaaac accgcagtca
      301 tcgaatctgc acaagcattg gggttagatc tacttgataa accaacggat caaactatcc
      361 gacttgcttc cagttatgcc ttaggagaac ttattaaaga tgcactgctt caagaagtag
      421 aacaaattat tgtcacttta ggaggaagcg ggtgtagcga tggtggtcta ggattactcc
      481 aatccttggg tgcttcttta gaagggtaca cagaaggaaa tcctttatta tctactaaaa
      541 aacttcattt tgatcgaaga aacgttcttg tttctaaagt aaaattgatt atcgctgcag
      601 atgttaccaa tccatataca ggtcaacaag gagctgcttg gcaatttgga agacaaaaag
      661 gaggaataga tacgacgcta gctttcttag ataaacaagc aggaaagatt gctcagcaaa
      721 taaaagattt ctgggaggtg gatttagatg atattccagg aagtggagca gcaggcggta
      781 ttggtggagc cctttttttg ttgggagcga agatggtttc tggtttcgat ttagtcagcc
      841 aaatcactgg attggaaaaa aagatcgaac aagcagatgt catcattaca ggagaagggc
      901 ggatcgatca gcaaacgatc cacggaaaag ttccatacgg tgtagcagtg cttgcaaaaa
      961 aatatcgaaa accaataatc gctatttgcg gaagtagaga ccaagagcta gaaggacttt
     1021 ctgattttct cccaattgtc ttaagtattc atttgggtcc aataggttta gaagaagcaa
     1081 tggaacacag gcaaacatta gaaaaaacaa aaatcttagg acagacactt agcagatttt
     1141 tcaccatcct cccgaagtag ttgacaaaat cattttcttt atgctatcgt aatttcaaat
     1201 ataggacaaa gtgagggatc cgtgcattga aaaattaagt cgattgatga aagctgcatt
     1261 cagactgtac cttgtggaga caaggaagca gtgtgcagat tttcgggatt ggcttggttt
     1321 tttcgatgta tgggtctttt tgtgtgtatc caacccttgc atcctcttta gccagttctg
     1381 aaaataggac tggtcttttt ttacgaggtg atggaaaatg tctaaaatcg aaataaaaaa
     1441 tctgacattc ggctacgaca gccaaggcac attattattt gaacaagcaa atctaaattt
     1501 tgacacacaa tggaaactag gacttatcgg acgaaacggt cgaggaaaga caactttact
     1561 gaatattcta caaaacaaac taccttatca agggcaagta atccatcagc aagaatttgc
     1621 ctatttcccg caacagacaa aagataaaga acgtttaacc tattacgtgt taaatgatat
     1681 tacggatttt gagatatggg aaatcgaaag agagctccaa ttgatgcaaa cagatcctga
     1741 aatcttatgg agagaattca gcacactatc ggggggagag aagacaaaag tcctactggc
     1801 acttttattt gtggatgaca ctcatttccc gttaatcgat gaaccaacga atcatttgga
     1861 tatctctggt agaaaacaag tagcggctta tttgaaaaag aaaaaacaag gcttcatcgt
     1921 ggtcagccat gaccggggat ttatcgatga agtagtggac catgttttag caatcgaaaa
     1981 aagtcaactg gaactttatc aagggaattt ctctatctat gaagaacaga aaaaacttcg
     2041 tgatgaattt gaaatggctc aaaatgaaaa attgaaaaaa gaagtcagta ggctaaagaa
     2101 aacagcagct gaaaaagccg aatggtctcg ttcccgagaa ggagataaaa caaagaaaca
     2161 agtcggattc atcgatactg aatctagacg agtgaataaa ggagcagtgg gtgctgatgc
     2221 tgcacggacg atgaaacgat ccaaagcaat cgtgaatcgg atggagaccc agatcagcga
     2281 gaaagaaaaa ctattaaaag atatcgaata tatcgattct ttgacgatga atagccaagc
     2341 gtctcaccat aagcgacttt taagcgtaga agatcttcaa ttagggtatg aaaatctgtt
     2401 attcgagcca attcatttta caatcgagcc tcatcagcgg gtggcgattt caggtcctaa
     2461 cggtgcagga aagtcatcca ttatccatta tcttctgggg gcattcaacg gcaaggttat
     2521 aggagaaaaa taccagccaa aacatctgag cattagttat gcaagccaaa attatgaaga
     2581 caatcgagga acgttggcgg aatttgcaga gaaaaaccaa gtagactacc aagcattttt
     2641 gaacaacctc cgaaagcttg ggatggaaag agatgttttt cataacaaga tcgagcagat
     2701 gagtatgggc caacggaaaa aagtggaatt ggctaaatct ttatcacagc cagctgaact
     2761 atatacatgg gatgaaccat tgaattattt ggatgtcttc aatcaagaac aattagaaca
     2821 actgatcttg aacgtgaaac ctgccatgtt actagtggaa catgatcaaa ccttcctgga
     2881 taaagtatct actgagatta tttctcttga gagaatctaa cccttgtaat ctcaagaaca
     2941 acaaggtatg gttaagggga actttgccaa cgaaggagag aatcacatgc tttatgtaac
     3001 gagacacgga gaaacaactt ggaacgcaca aggattagtt tgcggacggg cagatgtgcc
     3061 gctgactgaa aaaggacaga tgcaggcaca gaaactagca gaaaaggtag tagatttgcc
     3121 tgttccaatc acgaaaatca tccattcccc tcttcaacga gcaagagata cagcacaagc
     3181 agttgctgat cgtctcagct tgccgctgac cgttgatgaa cgattggtag aaatggattt
     3241 tggggattat gatggactgc caagcaaaga tgagaacttt caaaaagcac gtttagcgtt
     3301 cgctgtacga ttcccaaatg gggagtcagt cttagatgtg tatgcacgga tcgttccttt
     3361 attgaaagaa tgcatcgaag acgaagaaaa tgtctatctg ttagtttgcc ataatgcctt
     3421 gataagagtg atcaatgctt attttcatcc gatgcctaat gaggggttct ttacattcat
     3481 ggtagataat acagaattgg tttcttatga gtaattatgt ttttgtgtta tttaaataaa
     3541 atatttcaag gcactgcttt tgcttagcag tgcctttttt aggttatgac aattcttttg
     3601 ataatataaa ctcaaccttt agaaatgaaa tttaattatt ttaataaaag tattgaaatt
     3661 ttgtttcttt agatatatac tctagtcata gaaatgaaga cggatacaga aaaagaggga
     3721 taatatgttt ggcttttcaa tatttatgaa cgattctttg tcagaagaga agaaacagta
     3781 tatccgccaa atggcatcca atggctttgt cggtattttc acttccatgc atataccaga
     3841 agatgatgtt tcggcatatc aaaagcgatt gatcgaacta ggaagcgaag cgaaaaagaa
     3901 taaactagaa ttgatggtcg atatttcagg agaggcattg gaacgagcgg gtttttcatt
     3961 agaagatcta acgcctttga aagcaattgg tgtaacaggt ttaagaatgg attatcatat
     4021 ttccaatcag cagattgccg actggtcaca tcaattgaaa atcagtttga atgctagcac
     4081 gatcacgcct aaagatatcg atgaattgaa agaagcagaa gctgatttct cacagattga
     4141 agcttggcat aattattatc cacgtcccga aacagggctg gacaaagaat ggtatcagaa
     4201 aaaaaatcaa tggctcaaaa ttcaaggtct ccttgtccaa ggttttgtac caggagatac
     4261 agagttgaga ggcccactat atcaaggatt gccaactttg gaagaacatc gagggatcca
     4321 tcctcttgca ggcgctctag atctattagc aagtaacacg gatattgttt acatcggaga
     4381 tgcaggtctg tcagaaaacg ttcaggagca atttgcttct ttccaaaaag aacagacagt
     4441 cttgctccat acggaacctg tagatgaaga attttacgaa tatatattag ggaagcatac
     4501 gaatcggcaa gacgatgcaa gagatgtcat acgaagcgta gatgcacgtt ttcgagagat
     4561 tccgcctatc ccagcaagaa atacagctac gcgtatgaaa gggtctatta ctttagataa
     4621 cgaaaagtat ttgcgctata tgggtgagat ccaattaacc aaatatgatt tgccagcgga
     4681 tgaaaaagtg aatgtagtag ctaaagttat caaagaagag ctaccattga tcaaccaaat
     4741 caaagctggt atgaactatc aatttataag aaaagaagga agataaaaat gagcaaaatc
     4801 aatttagaga acctaacaac ggaacgcaga aaccaagaaa cttttggatt agatgagatg
     4861 agtatttctc aagccgttca actaatgaac aaagaagatc agaaagtggc cgctgcggtt
     4921 gaaaaagaac tgacaagtat cgaaccagtg attgctaaca cgattgagtc ctttaaaaaa
     4981 ggtggacgtc tgatttatat gggagccgga acaagtggaa gactaggtgt gttagatgct
     5041 gctgaatgcg taccgacatt cggtgtagaa ccggaaatgg tcataggtct aattgctggt
     5101 ggagaagaag caatgactgt agctgtcgaa ggggccgaag attcttatga gctagggcaa
     5161 gaagatctaa tcaagctgaa tttgacaaaa aatgatatag ttattggtat cgcagctagc
     5221 ggtcgtacac catatgtgat cggtggatta gattacgcaa aatcgatcgg tgctgtcaca
     5281 ggaacgattt cttgcaataa acaagccgaa atcagtaaac acgcggattt cccaatcgaa
     5341 gtcgatgcag gtccagaatt tttgacaggc tctactcgat tgaagtcagg aacagcacaa
     5401 aaacttatct tgaatatgat ttctactatc agtatgattg gtataggtaa agtattcaat
     5461 aacttgatgg tcgatgtcaa accaacaaat gaaaaactaa tcgaacgctc aaaacgaatc
     5521 atcatgcaag cgacagaagc tgattacgaa acagctgaaa agtactttga agaagcagat
     5581 caaaatgtta agctggctat cgtcatgatt ttgacaaata gtgataaaga ggaagctcaa
     5641 gcaaaattag ctgaagcaaa cggatttgta aaagggacct tatgaggggg aaaagaccat
     5701 ggcaaaaaac gaactgactt tggaagaact ggcaaaacaa atttataaag gggcaggcgg
     5761 catgggcaat gtagaaagca ttgtccactg catgactcgt gtgcgtatga agatcatcaa
     5821 tgatgatctt gtaaatgtct ctgaattaaa agcgattcca ggagtgcttg gtgtagtaga
     5881 agatgaacag cttcaagtca tcatcggacc tgggaaagtg aacaaagtag cacagcaaat
     5941 ggttgatttg gcaggcgtga aattaggaga aaaactttct tctgtaagta cagctacagc
     6001 aaattcatca gcatctggaa aagaccgtgt aaacgaacgg gcacaagaaa tgaaagcggc
     6061 acaaaaatcg aaacaaaaac catctaaaat caaatcggta ttaaaagaca tttctaatat
     6121 ctttgtgcca atgattcctg catttgtcgg tactgggatc gtggcaggga ttgccgcagt
     6181 tttagcaaac ttagtcacag ccggaacact tgatgcagca acatggcaac aatatatcga
     6241 tgtgatgaac atcttgaaaa acgggatgtt tagctaccta gttatctata caggtatcaa
     6301 tgctgcacaa gtttttggtg caacaccaac tcttggtgga gttatcgggg ccgttgtgat
     6361 gctgacaggg atgaatccgg aagcaccact gaaaaactta tttactggtg aagctcttgc
     6421 agctggacaa ggtgggatcc taggtgtcat cttcgctgtt tggctattgt caatcgttga
     6481 gaaaaaactg cataaagtag tacctgatgc ggtagatatc atcgttacac caactctttc
     6541 attgattgcc atcggtctga ttgaaatttt cttcatcatg cctttagcag gtttcatttc
     6601 tgatggcatg gtcggtggga tcaactgggt acttggcgtt ggtggagcat ttgccggctt
     6661 cgttctaggc acattattct tgccgatggt tatgttcgga ctgcatcaaa ttttgactcc
     6721 aatccatgtg caaatgattg atgaaactgg tcgtacgcta ttgcttccaa ttcttgcgat
     6781 ggctggtgca ggacaagtgg gtgcagcatt ggcattatgg attcgctgca aaaaagataa
     6841 agaattaaca gaaatgatca aaggagcttt accagtcggg atcctaggaa tcggcgaacc
     6901 attgatttac ggagtaacat tacctctagg acgcccattt attactgctt gtatcggtgg
     6961 aggtatcggc ggggcagtga tcggaatgat cggaaatgtc ggggctatcg ctattggacc
     7021 ttcaggagcc gctttgatcc cattgatctc tgacggtaaa tggttaggct acatccttgg
     7081 attattggca gcttatgctg gtggcttcgt tgctacattc ttcttcggta ttcctaaaga
     7141 ccgtttagaa aaagaagaat tagcgactga aacagccaca gtaaatgaag tgcctgaaaa
     7201 agtagtacct caaacttcag ctgaaagtgt gactatcctc tcatcagttg ctgacggaac
     7261 agttgtttct ttagataaag caagtgatcc agtttttgca caaaagatga tgggtgaagg
     7321 ctactttgta gaaccagaaa acggacatat ctattctcca gttactgggg tagtcagctc
     7381 tgtcttccca acgaaacacg ctattgggat cacaacgcca aatggtttag aaatcttgct
     7441 tcatatggga atcaacacag ttgacttagg cggtacgcca tttgatgtga aagtaacaga
     7501 agggcagcaa gtgacacctg atacgcttgt agcagaagct gacttagaag cgatcaaagc
     7561 agcaggcaaa gaaacatcca tgatcgtctt ggtaaccaat atggatcgtg taaaaaactt
     7621 tgtcttggaa aaaacaggta aagcaaaagc aaaagcacct gtgatggatg tcaaagctta
     7681 atatgataga aacaatagaa acgaaa
//
LOCUS       DACCVH010000248         7441 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.115, whole genome shotgun sequence.
ACCESSION   DACCVH010000248 DACCVH010000000
VERSION     DACCVH010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.115"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            205..1473
                     /locus_tag="IVV98_002995"
     CDS             205..1473
                     /locus_tag="IVV98_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP7808560.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            1960..2424
                     /locus_tag="IVV98_002996"
     CDS             1960..2424
                     /locus_tag="IVV98_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7808561.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            2408..3037
                     /locus_tag="IVV98_002997"
     CDS             2408..3037
                     /locus_tag="IVV98_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7808562.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            3391..4869
                     /gene="msr"
                     /locus_tag="IVV98_002998"
     CDS             3391..4869
                     /gene="msr"
                     /locus_tag="IVV98_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP7808563.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            4916..5362
                     /locus_tag="IVV98_002999"
     CDS             4916..5362
                     /locus_tag="IVV98_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP7808564.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(5561..6076)
                     /locus_tag="IVV98_003000"
     CDS             complement(5561..6076)
                     /locus_tag="IVV98_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7808565.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            6193..7395
                     /locus_tag="IVV98_003001"
     CDS             6193..7395
                     /locus_tag="IVV98_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7808566.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         2361 a         1274 c         1538 g         2268 t
ORIGIN      
        1 attacttgtt aaatagttat tcaaacgacc atcaatttaa ggcgtgaatg gagaagaata
       61 ttcttcattt acgtcttttt atgcagaaaa agcaaattta ttaaaaagaa acaaatgtta
      121 tttaaatatg gacattgact tgcttttact tttttagtta cactgttatt taggaaaagt
      181 ttcataattc aaaggagaaa aaagatgaaa gcaaagaatt tattatttag cgttattctt
      241 ttaggaaatc tagcagttgc caacacaaca gtgctagctg aagaatcgac agaaactgtc
      301 gcaactcaga catcgagttc ttcagaaaca ggaattgaaa acgatacaga aagtactttg
      361 cagtcagcta ctgtctcaga aaatacaatt tcaaccgaag aaccaacaac tgaaacaaca
      421 gaacaaacac aaaccgaaga cagtacatca gcagaagctc agaacaatcc agagaatgca
      481 gaagaaatca cgaaccaatt gacagatggg caaacattga cacataccca tcaagcagat
      541 ttgtctgaat tcgaaaacta tactggctat gctttttatg ctcgctcatc tgctaattct
      601 caacaagcgt tcattgatag tattgcctca actgcacaaa gtttggcaag tgccaatgac
      661 ttatatgcat cagtcatgat tgctcaagcc atcgttgaaa gtggctgggg gaacagtact
      721 ttggcttctg cccctaatta caatctattt gggattaaag gaagctataa tggccaatct
      781 gttacgatgc ctacttcgga atatgtgaat gggcaatgga ttacggtgaa tgccgctttt
      841 agaaaatatc cttcgtacaa agaatcattg caagataacg taacggtatt gaagacgact
      901 tcttttcagc caggcgttta ctactattcc ggtgcatgga aaagcaatac gaactcttac
      961 aaagatgcta cggcttggct aacaggtcgt tatgccactg cgcctaatta tggttctaca
     1021 ttgaacaatg taatcgaaac ctataatctg acacagtatg atacagcacc aacttcaact
     1081 tctccgatgt atcgtctgta taaccgtcat acaggagaac atttatatac attgaatgcc
     1141 ggagaaaaaa attatctgcc aactgtaggc tgggaatatg aagggattgc ttggcaagca
     1201 ccaaacagcg gacaacctgt ctaccgttta tacaatcctt acagtggaga ccatcattac
     1261 acaatggcac aatctgagat caactcttta acaaaaatcg gttggcgtta tgaaggtcta
     1321 agtttttatt ctggtggttc caagccaatt tatcgactat ttaatccaaa tgaaaaaact
     1381 ggtacccatc actatacctt gagtgctaag gaaagagatt ggctaacacc gatgggctgg
     1441 agatatgaag gaataggatt ttatggttat taaaaagagg tagtgaaaaa gctgccctgc
     1501 atcaagtagt aagaacagcc aaacaaaaac agattttcat gttttttgtt tggttgaact
     1561 tattaccgca gatgcaagtt tttgaacacc gtttactcaa aaaaggttgt gacaacatct
     1621 tgtcataact tttttattac tgtttaagca tactgatcca atttctaata ttcgacggga
     1681 ttcttgcaaa aggcgatttc ggaaattttt ggcggtgtaa aattatctac tgcagaagag
     1741 ctatcttcta tagtttgata agaatcaata atcttggttt tagcgttgtg ctttctttat
     1801 cattttttcc gttcattcta caaaaaattt cttttctcta tacttttcta ttgagagcgt
     1861 tttttttatt acacagctga ttctttgact tttttctttt tttattctat tattgacaag
     1921 tcaatcgttg acgagtcaat tattagaaag gaggaaatta tgtctttaga agagattagt
     1981 caccttttat atcaaatcaa attagccgat caaaaaatcg tccagatctt tgaagaaaat
     2041 atcggtataa gtcttactag atacgagatc atgatgagac tgaaagaaga aaatccattg
     2101 ctacaaagca gtttgcaaga aaagttgcag attgatcaag gagcagttac tcgtcatctg
     2161 aaggtattgg aagcaaatgg ctatgtttcg cgtcagagaa atcctcagaa caaccgggaa
     2221 gtgtatgtag cgctaacaga aaaagcccag aagaaaatca agcattgtga aatggaccat
     2281 aaagatacag gttccgtgct atccccggct ttcagcgatg tagaaatgaa acaatttcta
     2341 acacttttag ataaattgaa tacccaactt tgcaatataa caacagaaac gaaagaggtt
     2401 aataataatg gaacaaaaaa atgatttttc aacaattatg actggtagaa gatccgttcg
     2461 cgtatatgat gaaacataca aaatcccaca cgaagaaatg ctggaaatga tcaaagaagc
     2521 gacgactgca ccttcttctg tcaatatgaa accatggcgc tttgtggtcg ctgaaagcga
     2581 ggaagcaaaa gaaatcttgc gtcctttgat ccgtttcaat acgagacaaa atgatacttc
     2641 ttctgcaatg gtcatgattt ttggcgatat gcaatgttac gaatatggcg aagaaatcta
     2701 caaccaagct tacgaatcag ggaagatgcc aaaagaagtc agagatcaac aattagctgc
     2761 gatcattcct tattacaaga gtttttcaag agaagaaatg aacgatgtag tcaaagtcga
     2821 ttctagctta gcggctatgc aattcatgtt agttgcgcgt gatcatggct atgaaacaaa
     2881 tccaattggt ggattcgaag cagatcagtt ggcagaggca tttggtttgg ataaagaccg
     2941 ttatgttcca gttattattt tatcaatagg aaaagcggta gaagaaggtt acgagtctgt
     3001 tcgtttagca ccagaaaaga tcactatgtt cgaataaaag gttttcagtt actattcagt
     3061 agctattgct ttttttgaat cgtgtgtggt aacctaataa aaaaggaggt cggaaaaatg
     3121 actgcatcga tgaaattacg tttcgaactt ttgaataaca actaaataaa ttcaaaagac
     3181 atgtataaac aacaatttca tggatggagt atgtccattt tttcgaacga cagtagaata
     3241 ggtgaaagct atgacagatt tggtgattta gtcatagtta tttcgttcag agtaggaaaa
     3301 gatgtgatgc agtttttttg caaacagatt tttctgctct tttttagtat cgataattgt
     3361 tgttttacat gaaataggag tgtaaaacat atggaaaatt tagcagtaaa tataacaaat
     3421 ctacaagtca gctttggcaa ccagctagaa ctatctattg attctcttcg tgtctatcag
     3481 caagatcgta tagggatcat aggagaaaat ggtgtcggta aatcgacttt gctcaaacta
     3541 atagccggtg aactttttcc cgatcatggg aaaatccaaa cagagatcac cttcaactac
     3601 ctgcctcaat taacctatct cgctgaagca aaggacctaa atttggaatt agccagtcat
     3661 ttccagttaa gactggaaga aacttcagag cggaaatgga gcggagggga agaacgaaag
     3721 atcgagttga tacgtcttct ttcttcttat gaacaaggga tgcttctaga cgagccaaca
     3781 acccatctag atagaaaaag tattgatcga ctgattgaag agcttcgtta ttattatggt
     3841 acgctggttt ttgttagtca tgatcgctat tttctagatg agctagcatc gaaaatctgg
     3901 gaagtaaaag acggagaaat ccgagagttt tcggggaatt atagtgccta tctcactcaa
     3961 aaggaattgg agaaaaagac tcagctacga gaagcagagt cgatcatgaa agagaaaaaa
     4021 cgattggaaa aatcgatcca agaaaagaaa aaacaagcgg aaaagttgga aaaagtgtcc
     4081 agtaaaaaga aaaagcaaca aatcagactg gatcggttgt cttcctctaa acaaaaagac
     4141 agtgtacaaa aagccatcca aaagaatgcg aaaacattag agagaagact ccaaaaaata
     4201 ggagaaacaa ccaagccgca gcagatgaaa caaatccgtt ttccagtacc aaaatctctt
     4261 gaactccaca gccgctatcc catcatggga caaaatgtcc aattggaaag aagtgggaga
     4321 acattactgg taaatggtga ttttcagttt tctttaggta aaaaaatcgc gattgtcggt
     4381 gaaaatggtt caggtaagac aaccttatta gaacatatcc gcaaacaagg agaaggaatc
     4441 cttctctctc cgaaagtaag ctttcaagta tatcagcaaa agggttatca aatgacatct
     4501 gaagaatcca tcattcgttt tgtcatgaga caaacagagt tttcagaatc gcttgtccgt
     4561 agtttgctga atcacttagg gtttgctcag gaaactttga cgaaaccgtt atgtacatta
     4621 agtgggggag aagcgacccg tctgacgatt gctttgcttt ttactaagcc aagtaatgtg
     4681 ttgctgttag atgaaccgac taattttatt gatatggcaa cgatcgaagc tttagagaag
     4741 ctaatgcaaa tatatccggg aacgattttg tttacttctc atgattctta ctttgtcgag
     4801 cgtacggctg atgaagttta tgaaataaaa gggcagaaaa taaaaaaagt acttacgaga
     4861 aatttttaaa tgtgctacga tgattttcgt gacaaattta aaggagtggt acagattgcc
     4921 tacaaataaa aaagaaggaa taatttttac aacaatgatg tgttttttga tggtcttggg
     4981 gatgagcgcg tataatttat ggctgcatca agatcttcat ttatcaagtt tgttgattgg
     5041 tctagtgcct ggattcgtgg tggctttcat tttggatgtc ttcatcatcg gtgtgctggc
     5101 gaaaaaaatt gcctttaaac taccagtaaa tccagaaagc aaggtccaaa tgatcttaac
     5161 tatttcatgc ttgatggttt taggaatggt gacatgtatg tctttattcg gtgtgatcat
     5221 ggaacaagga atacctgatc aattattctc tgcttatatg aatgcttgga aaatgaatgt
     5281 gattgccgct ttaccgttgc agttgatcat cgttggcccg ctttcaagaa gtgtgctaaa
     5341 agcaattcaa agtaatgaat gatggaacac tgttatttga aaaaaggcct tggcatgctt
     5401 tttgtcatag tctcttgaat gcagttctag aaaaatagtg atccgaacga taggttttgg
     5461 cctgtcgttc ggatcgcttt ttcttttcca actgtattgc tcttttattg aagataattt
     5521 gctcttcaat agatatttct agaaaggttc tgtttatccc ttactcaaaa aactgctgca
     5581 tttgttctct tacttgctga caccattgga gttcctgctg acaaagcata attctgcgct
     5641 ggatcacaac ataacgtcca aattcttgtt tcttgtctag cgagaggtca ttcaattttt
     5701 tttgattttt ttgcatgatt ttgttcagct gttgttctct agtgaatagc agtccagtag
     5761 ctgttgtttt atcgagcgtc gaaaaagcat agatttttgc tagaaattca tctttttgcg
     5821 taggagcggg agtttcctct ttgatccatt cctctacaag agcacgtcct tcatcagtca
     5881 agtggtagat ctttttttga gagtgctcgt ctttgtccaa aacggtcaca taaccctgct
     5941 ggtctaactt ggcaagcgtt gtatagatct gactgtgatg ggcttcccaa aaaattgtga
     6001 tcagctgctt caattcatac ccagaacgtg gtttggataa aagcacgcat aataatatat
     6061 aggctaaagt attcataaaa atcctacctc tcgtcttatt ttctttatta tatcacagta
     6121 aagtttccac gttttacatg tgcatattga catgtaaaat aaatcatgta tgatgctaat
     6181 agagagaaag ggatggaaat attggagaat caaatagata tacaagaaca aacaaatgaa
     6241 gaaacaaagg ggaaaagttc agcgctagtt gtagcagcta cctgtatgat cgcttttatg
     6301 ggagtgggtc tagtagaccc aatcttaaaa acgattgctg cacagttaaa cgctacgcca
     6361 gctgaaacga ccctgttatt tactagttac atgttagtca ctggtgtggt gatgctattt
     6421 acaggtttct tatctagtcg gatcggtttg aaaaaaacat tgatgacagg attgtttatc
     6481 atcgttgtat tcgctggtct tggcggatta tctgggaata tcggaatgct gattgggtta
     6541 cgtgccggct ggggtgtcgg gaatgcttta tttgtctcta ctgctttagc aacgatcgtc
     6601 agtattttag ttggtaacac agaaaaagca atcatgatgt atgaagcagc acttggctgc
     6661 ggaatggctg ttggccctct agtcggtggg gtcttgggca gtggttcatg gcgttatcca
     6721 ttttttgggg tagcattttt gatgttttgc ggttttatag ccctagcggt acttttacct
     6781 gaaactgaga aaccaaagag aaaagtaggc ctttgggaag gtgtcaaagc gttaagcaat
     6841 cataaacttc gttcagttgg actaatcgca ttgttatata atttcggatt ctttacttta
     6901 cttgcgtatg cgccattttt attgattggc tattctgaat tagaagtcgg ttttgtattt
     6961 tttggctggg gtgtgcttct ggctattgct tcgattttcg ttgcaccggc tcttgagcgg
     7021 aagtttacga cttatcggac aattttagca gcatttgtct tattcattat ttgtttgctg
     7081 ttattaggag ctggaacttc tatgccagtc cttgtaccga tcagcattgt gttagcagga
     7141 tttttccaag gaattatcaa tacactgttg acgacgattg ctatggaaat accaggtctg
     7201 caacgaaacg ttgcttcgtc cagctatagt tttgtccgct ttttcggtgg agctttagca
     7261 ccatttattg caggtgtgat tggtgaacat attggtgaaa gctatgcgtt ttattttgca
     7321 ggtgccattg ttcttatcag tgtatgttgt atcatttatc accgtaatta ttttgctaca
     7381 aatgaagaag aataagaaat cagaggttgt gaaaaagctg tcctgcatca agtcataaga
     7441 a
//
LOCUS       DACCVH010000249         7330 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.117, whole genome shotgun sequence.
ACCESSION   DACCVH010000249 DACCVH010000000
VERSION     DACCVH010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.117"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..448
                     /locus_tag="IVV98_003002"
     CDS             <1..448
                     /locus_tag="IVV98_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808567.1"
                     /translation="PAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVD
                     SLKDLSAPNSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYA
                     VINRDERRDVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            452..655
                     /locus_tag="IVV98_003003"
     CDS             452..655
                     /locus_tag="IVV98_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808568.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(955..1191)
                     /locus_tag="IVV98_003004"
     CDS             complement(955..1191)
                     /locus_tag="IVV98_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7808569.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(1374..1745)
                     /locus_tag="IVV98_003005"
     CDS             complement(1374..1745)
                     /locus_tag="IVV98_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7808570.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(1742..3070)
                     /locus_tag="IVV98_003006"
     CDS             complement(1742..3070)
                     /locus_tag="IVV98_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP7808571.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(3031..3360)
                     /locus_tag="IVV98_003007"
     CDS             complement(3031..3360)
                     /locus_tag="IVV98_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP7808572.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(3618..3988)
                     /locus_tag="IVV98_003008"
                     /pseudo
     CDS             complement(3618..3988)
                     /locus_tag="IVV98_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            4133..4318
                     /locus_tag="IVV98_003009"
     CDS             4133..4318
                     /locus_tag="IVV98_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7808573.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            5261..5920
                     /locus_tag="IVV98_003010"
     CDS             5261..5920
                     /locus_tag="IVV98_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAP7808574.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            5923..7266
                     /gene="vanS"
                     /locus_tag="IVV98_003011"
     CDS             5923..7266
                     /gene="vanS"
                     /locus_tag="IVV98_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP7808575.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRMFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
BASE COUNT         1817 a         1765 c         1857 g         1891 t
ORIGIN      
        1 cccggctgtg ctgcaggagg cgctacggac ggagcagcac agccgggggc gggccgtccc
       61 cggcgatttc aaagtccacg tcaccgcttt gcatgacagc cggattgaaa ccgaggcccg
      121 gcgtattgtg gacagcctga aagatctgtc cgcgcctaac agccccaata aaacgcattt
      181 catggtggag atctccccgc actttgcggc gattgcttcc accaaggata atgaccggct
      241 ctttgccatg ctgccctata aatccctgtg ttttaccggg atgaaaggca ggcatggcgt
      301 gtatgccgtg attaaccggg acgagcgccg ggatgtgagt attcgcaggc cccggccctc
      361 tatccgcaag cagctatccg acagcaaaca ggccgccagc ccaaaaaagg cggcggccag
      421 aaccaaaaag aatgaattgg aggtataagg aatgatgcac tttaccgtgg aggaagaaaa
      481 cctgatctgt atgtaccaca atgcagaccg gcgcagaacg ataaacaggc tcaccgccgt
      541 catgccggtt atggatgggg atatgcgggc gcaggcccag cagacccttt ccaagctgga
      601 acgcatgacg gatgccgact atgacggcca gaagttccac ttcacagacg aataacgaac
      661 agcagacgcc gggcgcggcg gccatgtggt cgcttgcgtc cggcgtcttt tctttttgcc
      721 tattcctacg catttagaac ccggtattgt cggggatagg atgaagtatt cgcttgcccc
      781 tgcaaacatg cgggagaagc cttgcagcgg gcggttttca atcccttaaa tgcgtaggtt
      841 gcagctataa ttagacccct gaaacagata tagccgcgca gcgggtgtat ctgtttcagg
      901 ggtgtgcagg tgatagccgc aaagcggcgt aagagggtgc agccctcttg ccgtctatct
      961 ctgttccagc gggaagctcg gcaatgcttc cagcagtttc agggaaatgc gctgccgtat
     1021 atcttcgtca atgactttct tctttttgcc gtttgcctgt ctgatctcca ccgtggaaag
     1081 ctcgttgatg tagtcagcat aatgggccaa cactttttcc gtggcccacc tctcaccggc
     1141 aacggcggct ttgatcgttt catagtccag cagcttttct tgtccgtcca tcctgatacc
     1201 cccgtcagac tgattttttc tatgatacca tattcggaag catggaacca gagaaaacgg
     1261 cgcttttctg ctggtaaatt ctacgcattt agaacagcac ttcggcgggg ataggataaa
     1321 acacccacat accccgctga ccatgccgga aaagccttga aatataaggg cttttacagc
     1381 tctaagtgcg taggtttcca gtatcttttc cgctggcgct cggcctcttt gcggcggcgc
     1441 atccgtttgg agcaggccgc gcagtatttg gcccggttag acttcggcgt gaacgtggcc
     1501 ccgcactcac agcagcgttt cacttcgtcc cggtctttgg tgatctcggc atacagggcc
     1561 gcatccagcg ggaggacagc ggccttaaac cagcggcaca gaagcgaata ggaaatgctc
     1621 tgtacgcaaa tacattcttc gccgtcgtcc agcaacaggc agttgccgtc acaatagttg
     1681 cagcactcat gcgtcagctt ccgggccttg cgatattgag ggtaattcat tcgtggaata
     1741 ctcatagctc ttgcgtccat tcctttcccg gcgtcatacg caaaatgccg tccacattct
     1801 gcttgatgat gccgtattcc tgcatctgct ttttcgcttc gccgtacttc tcatacagcc
     1861 gttccttttc ctcggccaat cgcttgtact cggctttcag ggcgtacaga tcggggagct
     1921 ttttcacacc ctgtcccttt agggcctttg ccgcagcttc atacaaaatc aacgtgcttt
     1981 catgctcacg ccggaatttt gccttatccg ctgcattgcg gtattccata gccacgggcc
     2041 agagctgctt gtaggtagaa atattcttta tcagcaccgc catatccgca agccggtgtt
     2101 ccatagcttt gagggtagcg gcggcctcgt cgctggcggc ggtgatctcg gccactttgc
     2161 tttccaaatc cgggtaggtg tctatcccat gttcagtcag gaaattcaaa gtctttgcgg
     2221 cctgcttcaa attgtggagc ttcgcccacc tctcatagcc tgccgactgc tgggccttaa
     2281 tgttgttttc cagatcaatc cgcaaagaaa tccccttgcg ctctttgggc gctctggtga
     2341 taacgcggcc tttgatacgc tctttgatgg cttcctcggt gtaggcttcc cccaatgtct
     2401 tgcagcgggt aaagcgttcc tgtccgggag cgcggaaaga aataaacttt cccggcttga
     2461 tctcatagcc ctgcgcctgc atgagccgca ggaaatcatc aaaatctttt gcctgcggga
     2521 tagcggcgtc aatggctgct ttgagcttcg ctttccagct cgtccctttc cgctgggcgt
     2581 cccactcggc atagctcttg cccttactct ggccgggctt caccacggac aatccgtttt
     2641 ccttgcacag cctgtcgctg gtgcgccgga tataggcata gctctgtttg ttggaaatgt
     2701 acttgcgctg atttaccata tccacggcac agaaaataat gtgattgtgg acgtggccct
     2761 tatcaatatg ggtagtcagc acatagggat atttcccttg cagcacttcc tcggcaagct
     2821 gcttcccgat ctcatgggcc tgttccggcg tggcttcgcc gggggcaaag gattgtatca
     2881 ggtggtggcc cagattattg cccttttggt atgcctgcgc cagcagcatt tcaaattcaa
     2941 tgtccgctgt ttcataagag caggcaaagg aggccaccag cagcttgccg tcagttttgt
     3001 ccgggttctc gatgtagtca agggcttttt tcagcgttga cttgatagga tgtatctttg
     3061 taactgccat atctgcgcca gcgccccctt tatatcctcg atgtcctgtg cgtacaccgg
     3121 ccccataccg ttcagcctct ttgcaatctg attgacgttg acgccgatct tctgtatctc
     3181 ggcggtctgc gcccggatgt cgctggtgtc catgttgacg atatagccgt caatgagcat
     3241 cttccgggcg taggctgaaa agttcttcgt atgcagcagc gccattttct gttcaatcat
     3301 agcccgttcc tccggcgtca cagggacgcg cagcacgatt tttcgctttc tgtttgccat
     3361 gcttcaccgt cctttccatt caggggtttg gggatttccc caacaagcaa aacggacgcg
     3421 gcccggcagg gacggggcag gccgtttttc cgggagtggc tacactccct atgcttgcta
     3481 cgttactgtt tctccactaa caagacgttt ccaaagcccc aaactacccg caaaatagcc
     3541 ctctggaaag aaaaaagtgc aaaaaaatag aagctacgct gtgcagctcc cgctaaaagt
     3601 aaaacagagg atgccagtta cacatcctcc gtttcattct tcttcggctt ttcaattagt
     3661 atggcgctgt caatcgcgcc ctcgatgatc ggcaggtatt cttcggggca gagtttcagc
     3721 ttgtggctga ccctttgccg cagttcgctt tcctcccgca tgatctccgg gttaaagtag
     3781 cgttccacag gaagcccgca ggctttaata agctgtatga caaccggcag actgggaatg
     3841 gcccgtcgtt ttcgatgttg gcaagatagc gccagtcaat atttattttc tctgccattg
     3901 ctttgcgcga aacgcgcttt gcttgccggg ccgctttcac atccgcgccg aaagtttcaa
     3961 agccgggaca atcttcaata ttcgccatat cgcacctccc acttacattg tatatttcat
     4021 actctgcccg tggaatgttg gtatatgcac ctttcttaaa gtttatattt cacattttgt
     4081 ttcttttatt cttcgagcaa aagaattata atgtaccctg tggaggtgta ctatggacta
     4141 catgacgttg aaagaggcag gcgagaaatg gggtgtgccc ccacgatgga taaactacta
     4201 ttgtgctgcg ggacgcatcc ccggcgctgt aaagatggcg acgatctggc tcattcccaa
     4261 aactgcggaa aagccgattg acaggcgtac aaagaaagga aaggcggtta ctgaatagta
     4321 taatgaaacc ggcgcatttt ggatatggtt ttgaagagag agaaagcatg gtattttgtc
     4381 acggaaaaac tataagatga tagatggcag gctgctccag accgataaaa agtattctca
     4441 tctgaaacag aaagaaaaga tttacacatg gatgtatgaa gaagcgaaac tttatcatga
     4501 cagaaatgga aaatgcccga aacaaagacg aggaagctgc tgctgtatca gccgtatatg
     4561 gtagaattga aaaggccggc atctggattc tttatggtga agtctccaga cattggataa
     4621 ctgctggtct aatgcgcctt tgagtatggg gtgattgatt ttaataccgg ggaggtacgg
     4681 ctttttgagg aaaatattct gggatttaca tttggcgatt attacatttc ctgtaactgc
     4741 aaggacacgg atgatgaaga tatgaggaat atagacttgc tgattttcta ctgtcttgaa
     4801 cggtattagg actgaatctg ctgcgcggag tgcggcaaga gcgaccggag ggagtacaca
     4861 caggccctgc ctgtgtgaaa agccataccg caaggtgcat tcgcaaaaaa gaggccgcgc
     4921 attttgctga ggcttggggt gtccccaaca agcaaaacga gaacgccgca ggcgggcaag
     4981 tggtggatca gaatatccgt aaaggatatt ctgatccatt gcttgccagt attatcggga
     5041 tgttttgaca accgctgtaa tcgaaacatc ccaaacatta agaaggtgtt aattattatt
     5101 atcttgattt aattcgttta aaccaataat atagatacat acaccatgaa aagaagcgag
     5161 tatcccaatg acggatgatt aaaatccgaa aagaaatcgc tttgaaacta cagggaaact
     5221 acagactgtt atgttatctt cttaaaatgg agggattttt atgtcgatac gaattctact
     5281 tgtcgaggat gatgatcata tctgtaatac agtaagggcg tttctggctg aggcaggata
     5341 tcaggtggat gcctgcacag atggaaatga ggcatacacc aagttttacg aaaacactta
     5401 tcaactggtt attcttgata ttatgctgcc cggtatgaac gggcatgaac ttttgcgtga
     5461 atttcgtgcg aaaaatgata ctcccattct gatgatgaca gccctgtcgg atgacgaaaa
     5521 ccaaatccgg gcgtttgatg cagaggcaga cgactatgta acaaagccat tcaagatgca
     5581 gattttacta aagcgggtgg aagccctgct gcggcgcagc ggtgcgctgg caaaggaaat
     5641 ccgtgtcggc aggctgacac ttctgccgga ggatttcacg gtactttgtg acggtacaga
     5701 gctgcccctg acacgaaaag aatttgaaat ccttttgctg ctggtgcaga acaaaggcag
     5761 aaccttaacg catgaaatca ttttgtcacg tatatgggga tatgactttg agggtgatgg
     5821 cagcacagtc cacactcata tcaaaaattt gcgggccaag ctgccggaaa atatcatcaa
     5881 aaccattcgc ggtgtaggat accgattgga ggaatcataa taatggaaag aaaagggatt
     5941 ttcattaagg ttttttccta tacgatcatt gtcctgctac tgcttgtcgg tgtaacagca
     6001 acactgtttg cacagcaatt tgtgtcttat ttcagagtga tggaattaca gcaaacagta
     6061 aaatcctatc agccattggt ggaactgatt cagaatagcg ataggcttga tattcaagag
     6121 gtggcagggc tgtttcacta caataaccaa tcctttgagt tttatattga agataaagag
     6181 ggaagcgtac tctatgccac accaaatgcc aatacatcaa atagttttag acccaacttt
     6241 ctttatgtgg tacatagaga tgataatatt tcgattgttg ctcaaagcaa ggcaggtgtg
     6301 ggattgcttt atcaagggct gacaattcgg ggaattgtta tgattgcgat aatggttgta
     6361 ttcagccttt tatgcgcgta tatctttgcg cggcaaatga caacgccgat caaagcctta
     6421 gcggacagtg cgaataaaat ggcaaacctg aaagatgtac cgccgccgct ggagcgaaag
     6481 gatgagcttg gcgcactggc tcatgatatg cattccatgt atgtcaggct gaaagaaacc
     6541 atcgcaaggc tggaggatga aatcgcaagg gaacatgagt tggaggaaac acagcgatat
     6601 ttctttgcgg cagcttctca tgagctaaaa acgcccatcg cggctacaag cgttctgttg
     6661 gagggaatgc ttgaaaatat cggtgactac aaagatcatt ctaagtatct gcgcgaatgc
     6721 atcaaaatga tggataggca gggcaaaatc atttccgaaa tactggagct tgtcagcctg
     6781 aatgatggga gaatcgtacc catagctgaa ccgttggaca tagggcgcac ggttgccgag
     6841 ttgctgcccg attttcaaac cttggcagag gcaaacaacc agcggttcgt cacagatatt
     6901 ccagccgggc aaattgtcct gtccgatccg aggctgctcc aaaaggcact atccaatgtc
     6961 atattgaatg cagttcagaa cacgccgcag ggaggcgagg tacggatatg gagtgagcct
     7021 ggtgctgaaa aatgccgcct ttttgttttg aacatgggcg ttcacattga tgatactgcg
     7081 cttccaagga tgttcacccc attctatcgc attgatcagg cgcgaagcag aaaaagtggg
     7141 cgaagcggtt taggacttgc catcgtacaa aaaacgctgg atgccatgag cctccagtat
     7201 gcgctggaaa acacctcgga tggcgttttg ttctggctgg atttaccgct cacatcaaca
     7261 ttgtaaatat ttaaaactta aatgattttg ggctctttgt caaataggac tgatagagtg
     7321 agataagaac
//
LOCUS       DACCVH010000250         4822 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.137, whole genome shotgun sequence.
ACCESSION   DACCVH010000250 DACCVH010000000
VERSION     DACCVH010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.137"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            194..1000
                     /locus_tag="IVV98_003012"
     CDS             194..1000
                     /locus_tag="IVV98_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HAP7808576.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1845
                     /gene="vanW"
                     /locus_tag="IVV98_003013"
     CDS             1018..1845
                     /gene="vanW"
                     /locus_tag="IVV98_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAP7808577.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVFADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            1842..2813
                     /locus_tag="IVV98_003014"
     CDS             1842..2813
                     /locus_tag="IVV98_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAP7808578.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2806..3834
                     /gene="vanB"
                     /locus_tag="IVV98_003015"
     CDS             2806..3834
                     /gene="vanB"
                     /locus_tag="IVV98_003015"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAP7808579.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3840..4448
                     /locus_tag="IVV98_003016"
     CDS             3840..4448
                     /locus_tag="IVV98_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAP7808580.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         1361 a         1016 c         1277 g         1168 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaaaatcgc tttcccattt gctctttgaa acggattgcg cattatacaa ccacaatacc
     1201 ggatttgaca tgatatacca ggaaaacaag gtgttcaact taaagctggc agcaaagacc
     1261 ttaaacggct tattgataag accgggggaa accttttctt tctggtggct ggtacgccat
     1321 gcggacaaag atacccccta taaagacggc cttacggtga ccaatggtaa actcaccacc
     1381 atgtcgggcg gcggtatgtg ccagatgagc aatttactat tttggatgtt cctgcatacg
     1441 ccattgacaa ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt
     1501 gacgagatta aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga
     1561 aacgataccg actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt
     1621 caggtgttcg ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag
     1681 tatgtccgtg aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc
     1741 ttaggtaccg gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt
     1801 tatcccctcc cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca
     1861 ttactgtttt tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt
     1921 ttcatattat ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg
     1981 ctggcaatca atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg
     2041 cgctgagaaa ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg
     2101 atacgactgc cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca
     2161 gcgttgcgga ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca
     2221 tgcacgccgt ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg
     2281 atatgactgt gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc
     2341 ggggatttgg atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg
     2401 tccagcttga tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg
     2461 cggatacccg ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt
     2521 taatcaacac cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa
     2581 gcggaaagct gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata
     2641 ccgattgctc gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga
     2701 atgtgatcat cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag
     2761 aaaaaacaat caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa
     2821 gtcgcaatca tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata
     2881 gaaattgctg cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa
     2941 aacggtgtat ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc
     3001 gccatactct ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac
     3061 gaaacacggc gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt
     3121 gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc
     3181 tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc
     3241 gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac
     3301 cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt
     3361 acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt
     3421 gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg
     3481 attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa
     3541 aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc
     3601 gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga
     3661 gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc
     3721 aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga
     3781 atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta
     3841 tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt
     3901 acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca
     3961 tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg
     4021 gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc
     4081 gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc
     4141 gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg
     4201 caattgatct tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact
     4261 tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac
     4321 aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg
     4381 aatggtggca ctataagttg attgatgagc cataccccga tacctatttt aattttgccg
     4441 tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt
     4501 catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat
     4561 agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca
     4621 cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg
     4681 gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg
     4741 ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg aaccccaaaa
     4801 gttgaactat ttaatggact gt
//
LOCUS       DACCVH010000251         4220 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.148, whole genome shotgun sequence.
ACCESSION   DACCVH010000251 DACCVH010000000
VERSION     DACCVH010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.148"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            350..1741
                     /gene="amt"
                     /locus_tag="IVV98_003017"
     CDS             350..1741
                     /gene="amt"
                     /locus_tag="IVV98_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP7808581.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGFLAMTISMVVSLYEYPTFATSGFSLVFFLLLGGLLWFIPVALCAAEMATV
                     KGWEKGVSQTKRY"
     gene            2136..2609
                     /gene="dfrF"
                     /locus_tag="IVV98_003018"
     CDS             2136..2609
                     /gene="dfrF"
                     /locus_tag="IVV98_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAP7808582.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2736..3392
                     /locus_tag="IVV98_003019"
     CDS             2736..3392
                     /locus_tag="IVV98_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAP7808583.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3574..4104
                     /locus_tag="IVV98_003020"
     CDS             3574..4104
                     /locus_tag="IVV98_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7808584.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1398 a          601 c          897 g         1324 t
ORIGIN      
        1 aaattataag caaattgaag aaaaacttat gttgaaatga agaacaaatt tgagaaccgt
       61 agcgacactc gctgcggttc ttttttatat attttatatg aagtattctt tattccttat
      121 gaaaaaatat ctttaaaaat aaaaaaagac gaaaataaac ggttttctat aaaaagaaga
      181 ccgtttattt tttgtcttta tttgtgtgaa aaacgaaaaa gagcacaaca catcaagctt
      241 ttattaattg tctgtctttt ataaatgcaa gtattaattc aaaaaaacag aagaaaaaaa
      301 caactacacc ttcttttata ctcgtaatcg tagaaaggag gcgaaaaaaa tgaatacatt
      361 acctatcaat acaggagata cagcattcat gattttatgt acagcaatgg tttgcctgat
      421 gactcctggt ctagcttttt tttacggcgg attagcacgg aagaataata tactaacgat
      481 catgtctcaa tcttttctct ccgttgggat aacaacgatt atgtgggtat ttggtggatt
      541 cggattggcc tttggacggg atatcggcgg tgttattgga aacccggcag atttcttttt
      601 gatgagacat gttacaagct tccccaacat gtttcatggt gcaacgattc catttttaat
      661 gttctttctt taccaactga tgtttatcgt gattaccgtt cctttgatga caggagcttt
      721 tgcagggaga ttgaatttaa aaggctatat tatacttgtt attttttgga atctgctgat
      781 ttatttccct gtttgccact ggatatgggg tggcggattt ttggatcaga tgggatttag
      841 agatttcgct ggtggagcag tcatccacac gacagctgga ttcggctctt tagcatgtat
      901 cctcacactt ggtcaaagaa agattccttt aggagaaaga agtcagcata gcagtcttat
      961 ggcagctgct atcggtacag gactgctttg gtttggctgg ttcggtttta attccggtgg
     1021 tgcacttcga gcagatgaac aagcagtcaa tgcatttggt tcaacattca tcgctcttgc
     1081 atttgcgatg attacttggc tgatcattgc aaaagtaaaa ggaaatggct ttgattttgt
     1141 cgacgtacta acaggatccg ttgctggatt ggcagccatt acgccttgtg ccggttatgt
     1201 agaagcaaaa agtgccatgc tgattgggat cattgcgggt atcgtctgtc atgctgctgt
     1261 tgattttcgt aaaaagaaac aatgggatga tgcacttgat gtgtggggtg ttcatggcat
     1321 gggcggattc acaggtacga ttctgatagg gatctttgca tctaacagcc atttactaac
     1381 gaatccaagc agctggtact tcttagggat tcaagtgatt ggtgtcatca ttactgccgt
     1441 gtatgcctat gtgctgacaa cagtgatttt aaaatcggcg atgcacttta caacgatcac
     1501 tactacaaaa gaagaacaag aagaaggatt ggactttttc ttctttggct ttttggctat
     1561 gaccatctca atggtcgttt cattatatga atatcccaca ttcgcgacct caggcttcag
     1621 cttagtattt ttcttgttat taggcggttt gctatggttt atccctgtgg cattgtgcgc
     1681 agcagagatg gcaacggtga aaggatggga aaaaggtgtt tcccaaacaa aaagatatta
     1741 agaaacagcc catgtttacc tgcttgcaaa caaaagaata ttgctactag actaagagat
     1801 actacataag tgtgttggta tctctttttt gttgccgtga aacagcagac tatttcattt
     1861 ctgcttgatt accttaaaac ttattagtct atggtttgtc aagggcttgt tgcgtgagaa
     1921 atgctgaata tcacccttta caaaacatag gctgataagt aacttttcaa aagcagaaaa
     1981 gaaatggcaa tgcttataac aatatgatat aatgcagatg aagacaaaaa aggaatttgt
     2041 cgagctggtt agttcgagat aattttgagt ttgttaagat gtggtgcact tgatggaatc
     2101 acaggtacga catcatatta tggaggatga aatagatgat aggtttgatt gttgcgaggt
     2161 caaagaataa tgttataggc aagaatggta atataccatg gaaaataaag ggagaacaaa
     2221 agcaatttag agagttaaca acgggtaatg tggttattat ggggcgaaag tcttatgaag
     2281 aaatcggtca tccgttgcct aatagaatga atattgttgt ttccaccaca acagagtatc
     2341 aaggagataa tttagtttca gttaaatcat tagaagatgc attattattg gctaaaggac
     2401 gagatgtata catatctggt ggatatggac tatttaagga agctttgcaa atagtagata
     2461 aaatgtatat cacagaagta gatttaaata ttgaagatgg agatacattc tttccagaat
     2521 ttgatatcaa tgattttgaa gttttgatag gggaaacact tggtgaggaa gtgaaatata
     2581 cgagaacatt ttatgtaagg aaaaaatgaa ttgagtaaat tttggattta gggtgttttc
     2641 ataaatatat tgctttttat gcatatataa attgttgtaa gacaaattcc agtttgtatg
     2701 gggcgataaa atcagaattt gagagaggat tgaatatgaa taaggaatgg tctgaactta
     2761 ataaaacaat gcaggcacaa ataaaaaaga aagatactta taagaggggt attgatactt
     2821 tacttacttt acgaagtcag ttaatacaaa ccttagtatc tttcaaagaa gaattatgca
     2881 gagaagattt taactcaatc cccttcataa acgctgatgg ttatcatagt aagacgattg
     2941 cttattctat ttggcatatt ttccgcattg aagatatagt tgtgcataca gtgataaatg
     3001 aagatgaaca agtatttttt gcaggcaatt atcaagagcg tatcaattca cctatcatta
     3061 caacaggaaa tgaactcatg aaacagcaga ttgcagactt ttcaaaacag cttaatctgg
     3121 aagaattata tttatatatt ttcgaagtat gggaaagcac tgagaaaatg cttgaacggt
     3181 tatcttatga tgaattgaaa agaaaaatac cgaaagaaag aaaaggatac ttagaatcgt
     3241 tgaatgtagt aaacgacaat gaaaaagcaa tttggctgat tgattattgg tgtaataaag
     3301 atatttgtgg actaattcaa atgccgtttt caagacattg gattatgcac acagaagcct
     3361 gtttgcgtat aaagaacaag atacattcat aggcaaaaat ttcagtttgt agaactaagg
     3421 aaattggaat ttaaggagga ataaagtatg gttagtgatt ttataagagc agcatttcca
     3481 tggattttaa tgggtttatt tgtagcaatc agttgttccc ttatgagtaa aaaagagaaa
     3541 taaattcctg tttgtattta taaaagagaa aaaatgagaa aagtagtttt atttattgcc
     3601 atgagccttg acggatatat tgcggacggt aatggtggag tagcttggct aaatggtcat
     3661 ggaaatgaca atgaaaacat cgacacttat acagaattta ccaaagatat agatactgtc
     3721 ttaatggggt ggaatacttc tcatcaggtt gttactgaac tttctccgca agaatgggta
     3781 tataataaat ttacaactta tgtattaaca cataaagagt gcaattcttc ccaacaaatt
     3841 cattttacaa gtgaaaatcc tgttttatta ttggaacggc taaaacaaga agcaggaaag
     3901 gatatttgga tttgtggcgg agcaaatctt gttcagcagt tggtaagcaa aaatatgatt
     3961 gataaatatt acatttctgt tattcctact ctgttaggaa atggggttcg tcttttgggc
     4021 aacatagaca gggaaataaa gttaaggctt tgtaaaacac agacttataa cggaataacc
     4081 gatttgattt atatgcgtag ataactagag agaaacagaa aagctgttaa accgacggag
     4141 cgatccgacc acgttggcgg gaaaatcctt aagatttttc ggctctttgt caaatgatgt
     4201 tggtaaagag aaatcttaga
//
LOCUS       DACCVH010000252         4094 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.150, whole genome shotgun sequence.
ACCESSION   DACCVH010000252 DACCVH010000000
VERSION     DACCVH010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.150"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..601
                     /locus_tag="IVV98_003021"
     CDS             <1..601
                     /locus_tag="IVV98_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7808585.1"
                     /translation="RFLFPRFMHGTLIGKLSGGEKRRLFLLKLLIQQPNVLLLDEPTN
                     DLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVADKLLVFQGNGKQELYYGNMSSYL
                     LKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEWETIEDEIAELEEKISLLQEEMN
                     HQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEWVED"
     gene            613..1560
                     /locus_tag="IVV98_003022"
     CDS             613..1560
                     /locus_tag="IVV98_003022"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP7808586.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            1580..2107
                     /locus_tag="IVV98_003023"
     CDS             1580..2107
                     /locus_tag="IVV98_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7808587.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(2170..2823)
                     /locus_tag="IVV98_003024"
     CDS             complement(2170..2823)
                     /locus_tag="IVV98_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP7808588.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            2955..3797
                     /locus_tag="IVV98_003025"
     CDS             2955..3797
                     /locus_tag="IVV98_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7808589.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            3955..>4094
                     /locus_tag="IVV98_003026"
     CDS             3955..>4094
                     /locus_tag="IVV98_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HAP7808590.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DP"
BASE COUNT         1455 a          723 c          842 g         1074 t
ORIGIN      
        1 acgattttta tttccaagat ttatgcatgg gacactgata ggcaaacttt caggcggaga
       61 aaaacgccgg ttatttttgt tgaaactgct gattcagcaa cctaatgttt tattattgga
      121 tgaaccgacc aatgatttgg acatagcaac attgacgatt ttggaagatt attttagaag
      181 ttttccaggt gctgtgatca ctgtttccca tgaccgttat ttcttggaca aggtagcaga
      241 taagttatta gtattccaag gaaacggaaa acaagaactt tattacggaa acatgtccag
      301 ttatttactg aagcaaaaag agacccagca gcctgctgaa aaagcgaaac caaaaataca
      361 gagcaaggaa cctgctgaaa agaagaaatt atcttacatg gaacaaaaag aatgggaaac
      421 gattgaagat gagattgcag aacttgaaga aaaaatctca ttgctccaag aagagatgaa
      481 tcatcaagga gataatttca ctcgattaca agaattgcaa aacgacgtat ctgaaacaga
      541 agcacaactt gaagaaaaaa tggcacggtg ggaatacttg agtgaatggg tagaagatta
      601 ggaggaaaaa ggatggaaca agcgtatctt gacttaggaa gaaaattgtt ggaagaaggg
      661 catcgtaaag aagacagaac aggcacaggc acattaagct tattcggata ccaaatgcgg
      721 tttgatctgc aaaaagggtt tcctttgtta acaacgaaac gagtaccttt tggattgatc
      781 aaaagcgaat tgctttggtt tttaaaagga gatacgaata tccgctatct attacaaaat
      841 aaaaaccata tttgggatga atgggcattt gaacgctaca tcaaaagtcc agactataat
      901 ggaccagata tgactgattt tggccataga tgtttgacag atcctgaatt caatgaagaa
      961 tataaaaagc agagcaagct tttttgcgag aagatcctaa ccgatgattc ctttgctgaa
     1021 acatacggcg atcttggaca catctacggc tatcaatggc gtcactggga aacaaaagac
     1081 ggtggcttta tcgatcaaat caaacaagtg atcgaagcaa tcaaaaagac tcctgattct
     1141 agaagattga tcgtttctgc atggaatccg gaagatgttc ctagcatggc tttgcctcct
     1201 tgtcatacga tgtttcaatt ttatgttcaa gagggacggc taagctgcca attgtatcaa
     1261 cgcagtgggg atgtgtttct aggcgttccg ttcaacattg caagttatgc gttgctgact
     1321 cacctaattg cacatgaaac aggtttagcg gttggcgaat ttgttcacac attaggagat
     1381 gctcatcttt atatcaatca tatcgaacaa atgaaagaac aattgagccg agaaatacgc
     1441 gcatttccga ctttagtttt gaatcaggaa aagcagtcag tatttgattt tgagatggaa
     1501 gatatccaat tagaaggata tgacccacat ccggcgatca aagctcctat cgctgtttag
     1561 aatcagaaag gatgagaaaa tgttagctgc aatttgggca caggatgaaa acggattgat
     1621 tggaaaagaa gaccgtcttc cttggcgttt gccaaatgat ctgaaattct tcaaacaaat
     1681 gacagaagca aatacactag tgatgggacg aaaaacattc gaagggatgg gtagccgtcc
     1741 gttgccgaat cgtcagacga ttgttttgac gagagattct tcctataaag cagaaggcgt
     1801 gcatgtcatg catagtgtgg aagacgtgct tgctctggaa aaagaaacag acggtatctt
     1861 tttcatcgct ggagggtcag ctgtttatca agaatttctg ccattttgta cgatattata
     1921 ccgtacagtc atccatcatg tattcgatgg agatgcttat tttccacctg ttgactggtc
     1981 tgattggtca ctgatcaata ctagtcaagg agaaatggat gaaaaaaatc gttatccgca
     2041 tcaatttgaa acgtatcagc gtaatgagaa tcctgtaaaa agcgggacag gcgaattgac
     2101 gatataaaaa agctatggat agactagctg ttatttagag ctgtcccatc catagcttta
     2161 ttttttttat taagtaaaga ataaaacaga gaagtacata aaacctgcac ctaacataac
     2221 aaacaaatgc caaacaacat gcatatagcg gatagaattc aagctataaa agaatgcgcc
     2281 tatcgtgtaa gaaagcccgc ctgctaccat caaaataaca ccagtcattc caagagagtg
     2341 ataaagagga acagcagcca cgacacagag ccaccccata aaaatataga tgatcgtaga
     2401 tacttttgat actctctccc gtttatgcaa cgtcaacgct ttatatataa tgccaagaat
     2461 cgcaaacaac cagattaata caaataaagt ccaacctagc catcctcgga tactcagcaa
     2521 acaaaaagga gtataacttc ctgcaatcaa aagaaaaatc gaactatgat cgaatacttg
     2581 gaacaccttt tttgcttttg taaaaatcaa tgaatgaaac aaagtagacg ttaaaaataa
     2641 aagaatcatc atcgatccat agatagcata agagacaata tggagggagg aatgcaagtg
     2701 ggcacctttt actaaaagaa ccactagtcc cgcgatactc aatccagtcc caattccatg
     2761 ggtgactgca ttaaacactt catttaatat ttcatacgtt cgattaaatt tcgttttttc
     2821 catgaaaacg gctcctttac taggtgtaat taatgaaaaa tcattatttg tctgttatac
     2881 taaaaataga aattgtctta catgtagttt aacatgaata aggcatcttg ttaaagaaag
     2941 agagagagaa aataatgaca aatgtaaaaa tcgtaacaga ttcttcatgt acgatggaaa
     3001 aaaatgtacg cgatgcttta ggcattcgtg tcatgccgct atccatcatg atcgacggaa
     3061 cagtatatcc cgatgatgac caactagacg gcgaaagatt tatggaaatg atggcgaaag
     3121 caaaaaatct gcccaaaaca agccaaccac caattggaga attcatctcg atgtatgatg
     3181 agctaggaga agacggcagt gaagtgattt cgatccatat gacaaaaggc ttgagtggaa
     3241 cagtagaagc agcaagacaa gccagtaatc taacaaaaac gaaagtaacg gttatcgaca
     3301 gtgataccac tgaccaagga ttatcttttc aggtaattcg agcagctgaa ttagcaaaag
     3361 aaggtaaaac agtagagaaa atccttgaag aagtcaaaaa agtacaagac aatacaaaat
     3421 tatacatcgg aatatccaca ctagataact tggtaaaagg tggaagaatc agccgaacaa
     3481 ctggtttgct gtctagtgtt ttgaacatac gcgtggtgat gaatttcgcc cattctgaat
     3541 taatccctgt aactaagggg cgaggaaaga aaacgttcga taaatggttt aataatttga
     3601 aaaatgaact gaaagaattg ccaaatgtgc gacaaatcgg tatttcacat gcggatgcaa
     3661 aagaattggc gcaagaattc aaagagggtt tgcaagaatt attcccggac atgcatatcc
     3721 ctgtactgca tacgaatccg gttatcgcta cgcatactgg taaagacgcg tttgcaatca
     3781 tgtattatgt agattagtcg aaaagaggat aagccctcag cctgaaaggc ttgcagctta
     3841 ttctcttttt ctttataaaa ttaggaaaat aattgttttc ttttttcata aagactacct
     3901 ttttgataaa atttttgata acattagaac caatcgaata caagaggtga aaaaatgaaa
     3961 ttaacgaaac gacatttgat cctcgttttg ttcccattat taattgcgat catcatctat
     4021 gcaggtttag ctgcttctat accgaaagct ggcccactaa tgaaaccagt aactactgtg
     4081 agagaagatc caaa
//
LOCUS       DACCVH010000253         2771 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.162, whole genome shotgun sequence.
ACCESSION   DACCVH010000253 DACCVH010000000
VERSION     DACCVH010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.162"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            110..193
                     /locus_tag="IVV98_003027"
     CDS             110..193
                     /locus_tag="IVV98_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP7808591.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="IVV98_003028"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="IVV98_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP7808592.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="IVV98_003029"
     CDS             complement(1318..2181)
                     /locus_tag="IVV98_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAP7808593.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="IVV98_003030"
     CDS             complement(2183..2455)
                     /locus_tag="IVV98_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP7808594.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="IVV98_003031"
     CDS             complement(2472..2681)
                     /locus_tag="IVV98_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP7808595.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DACCVH010000254          784 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16209
            SAMN14604034-rid9903103.guided.220, whole genome shotgun sequence.
ACCESSION   DACCVH010000254 DACCVH010000000
VERSION     DACCVH010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604034
            Sequence Read Archive: SRR11551443
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744179.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744179.1
            Genome Coverage       :: 170x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:47:41
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,968
            Genes (coding)                    :: 2,904
            CDSs (with protein)               :: 2,904
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 32 of 64
            Pseudo Genes (incomplete)         :: 26 of 64
            Pseudo Genes (internal stop)      :: 15 of 64
            Pseudo Genes (multiple problems)  :: 7 of 64
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604034-rid9903103.guided.220"
                     /isolate="UW16209"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Baden-Wuerttemberg"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            140..637
                     /gene="dfrG"
                     /locus_tag="IVV98_003032"
     CDS             140..637
                     /gene="dfrG"
                     /locus_tag="IVV98_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP7808596.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT          291 a           87 c          159 g          247 t
ORIGIN      
        1 tttgtgattt tgtggtatta tgataatata acttatagaa aaaattgctt attcaactaa
       61 cgggcaggat aatgagaaaa ggttttttga tagaaataag aaattagatg gtaaattagt
      121 taaaaaggct gtgttataaa tgaaagtttc tttgattgct gcgatggata agaatagagt
      181 gattggcaaa gagaatgaca ttccttggag gattcccaag gactgggaat atgttaaaaa
      241 tactacaaag ggacatccga taatattagg taggaagaac cttgaatcaa tcggaagagc
      301 cttacctgac agaagaaata ttattctgac gagagataag gggtttacct ttaatggttg
      361 tgaaattgtt cattcaatag aagatgtttt tgagttatgt aaaaacgaag aagaaatttt
      421 tattttcgga ggagaacaga tttataattt gtttttccct tatgttgaga aaatgtacat
      481 cacaaaaata catcatgaat tcgaaggaga tacttttttt ccagaagtga attatgagga
      541 atggaatgag gtatttgccc aaaaagggat aaagaatgat aaaaatccgt ataactacta
      601 ttttcatgta tatgaaagaa aaaacttatt gagttaacgg gtgcgttaat tgaagaagaa
      661 cagtaaagat aaagcacaag agcttgggat tactccaagc tctttttgtc atttgaaata
      721 aattatatct ttccaatcaa attgtttatc tgtaatccct aatctttgag caggtgtcaa
      781 aacc
//
